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Genetic Variation And Gene Expression Across Multiple Tissues And Developmental Stages In A Non-Human Primate, Anna J. Jasinska, Ivette Zelaya, Susan K. Service, Christine B. Peterson, Rita M. Cantor, Oi-Wa Choi, Joseph Deyoung, Eleazar Eskin, Lynn A. Fairbanks, John Blangero, Thomas D. Dyer Dec 2017

Genetic Variation And Gene Expression Across Multiple Tissues And Developmental Stages In A Non-Human Primate, Anna J. Jasinska, Ivette Zelaya, Susan K. Service, Christine B. Peterson, Rita M. Cantor, Oi-Wa Choi, Joseph Deyoung, Eleazar Eskin, Lynn A. Fairbanks, John Blangero, Thomas D. Dyer

School of Medicine Publications

By analyzing multitissue gene expression and genome-wide genetic variation data in samples from a vervet monkey pedigree, we generated a transcriptome resource and produced the first catalog of expression quantitative trait loci (eQTLs) in a nonhuman primate model. This catalog contains more genome-wide significant eQTLs per sample than comparable human resources and identifies sex- and age-related expression patterns. Findings include a master regulatory locus that likely has a role in immune function and a locus regulating hippocampal long noncoding RNAs (lncRNAs), whose expression correlates with hippocampal volume. This resource will facilitate genetic investigation of quantitative traits, including brain and behavioral …


Differences In Mental Health Education Across Baby Boomers, Generation X, And Millennials, Ashlyn M. Avera Nov 2017

Differences In Mental Health Education Across Baby Boomers, Generation X, And Millennials, Ashlyn M. Avera

Honors College Theses

There is no denying that mental illness has gained a strong prevalence in the United States. According to the National Alliance on Mental Illness, approximately one in five adults in the United States experiences a mental illness in any given year. Although mental health stigmas have played a role in the past, it does not mean they must continue to play the same role in the future. Research is now looking toward ways to decrease mental health stigma through increasing mental health knowledge. This study examines the starting point for which a society becomes literate in mental health. Using a …


Genetic Signatures For Helicobacter Pylori Strains Of West African Origin, Kennady K. Bullock, Carrie L. Shaffer, Andrew W. Brooks, Ousman Secka, Mark H. Forsyth, Mark S. Mcclain, Timothy L. Cover Nov 2017

Genetic Signatures For Helicobacter Pylori Strains Of West African Origin, Kennady K. Bullock, Carrie L. Shaffer, Andrew W. Brooks, Ousman Secka, Mark H. Forsyth, Mark S. Mcclain, Timothy L. Cover

Veterinary Science Faculty Publications

Helicobacter pylori is a genetically diverse bacterial species that colonizes the stomach in about half of the human population. Most persons colonized by H. pylori remain asymptomatic, but the presence of this organism is a risk factor for gastric cancer. Multiple populations and subpopulations of H. pylori with distinct geographic distributions are recognized. Genetic differences among these populations might be a factor underlying geographic variation in gastric cancer incidence. Relatively little is known about the genomic features of African H. pylori strains compared to other populations of strains. In this study, we first analyzed the genomes of …


In Place: November 27, 2017, Place Nov 2017

In Place: November 27, 2017, Place

PLACE Historical Documents

In PLACE is a newsletter designed to keep the Linfield College community apprised of information related to PLACE activities, as well as ways to bring the program into classes. Included in this issue:

  • Spotlight On: "What's the Big Idea"
  • Upcoming Events
  • PLACE in the News


Teaching For Epidemiological Literacy: Description, Prescription, And Critical Thinking, Peter J. Taylor Nov 2017

Teaching For Epidemiological Literacy: Description, Prescription, And Critical Thinking, Peter J. Taylor

Working Papers on Science in a Changing World

This working paper describes contrasting ideas for a sequence of topics as presented to students in a graduate course on epidemiological literacy. The premise of the pedagogical approach is that researchers develop their epidemiological thinking and practice over time through interactions with other researchers who have a variety of in-practice commitments, such as to kinds of cases and methods of analysis, and not simply to a philosophical framework for explanation. In descriptively teasing out what epidemiologists do in practice through a topic-by-topic presentation, I am prescriptively encouraging discussants to draw purposefully from across the range of topics and contrasting …


Grace Peterson Research Colloquium, Emma Pfeiffer Nov 2017

Grace Peterson Research Colloquium, Emma Pfeiffer

Grace Peterson Nursing Research Colloquium

Mental illness is commonly under-diagnosed, misdiagnosed, or untreated, particularly in the elderly population. An expected population increase for those 65 years and older, increased in health care expenses coupled with the moral and ethical obligation of health care providers to promote quality of life at all ages makes investigation to alternative treatments in this population is worth investigating. The purpose of this literature review is to synthesize existing studies to clarify the following questions: What are the effects of pet therapy on those experiencing signs and symptoms of depression and anxiety? Why is pet therapy still lagging in validated studies, …


Building Academic/Practitioner Teams For Human Rights Projects: Examples, Lessons Learned, And Pitfalls To Avoid, Theresa Harris Nov 2017

Building Academic/Practitioner Teams For Human Rights Projects: Examples, Lessons Learned, And Pitfalls To Avoid, Theresa Harris

Biennial Conference: The Social Practice of Human Rights

Academics are increasingly interested in getting out of their classrooms and labs to contribute their knowledge, expertise, and resources to help communities develop evidence-based policies. In addition to post-election initiatives such as the March for Science and 314 Action, many academics are joining “without borders”-type programs and organizations that connect academics with opportunities to volunteer their time and talents for “social good.”

One of the longest-running of these is On-call Scientists, an initiative of the American Association for the Advancement of Science (AAAS) that connects human rights organizations with pro bono scientists across all fields — life, physical, behavioral, and …


Adverse Childhood Experiences And Its Association With Cognitive Impairment In Non- Patient Older Population, Mohini D. Dutt Nov 2017

Adverse Childhood Experiences And Its Association With Cognitive Impairment In Non- Patient Older Population, Mohini D. Dutt

USF Tampa Graduate Theses and Dissertations

This study explores cognitive impairment and its correlation to early- life adverse experiences in non-patient population between the ages of 50 to 65. This developmental approach and observational study design explores cognition in pre-clinical Alzheimer’s disease (AD). Using a standardized neuropsychological instrument, the Montreal Cognitive Assessment (MoCA) and clinically administered questionnaire, the ACE (Adverse Childhood Experiences), I hypothesized that participants with high ACE scores will inversely have low MoCA scores.

My goal was to use a multiple linear regression model with 3 covariates and 1 predictor of interest (ACEs). At 80% power, a sample size of 40 was calculated as …


I’M Going To Tell You A Little About Myself: Illness Centrality, Self-Image And Identity In Cystic Fibrosis, Susan Horky Lcsw, Laura Sherman Licsw, Julie K. Polvinen Ba, Medhavi Saxena Md, Michael Rich Md Nov 2017

I’M Going To Tell You A Little About Myself: Illness Centrality, Self-Image And Identity In Cystic Fibrosis, Susan Horky Lcsw, Laura Sherman Licsw, Julie K. Polvinen Ba, Medhavi Saxena Md, Michael Rich Md

Patient Experience Journal

This study assessed the illness centrality of adolescents with CF and the specific ways that CF may affect adolescents’ identities, through the qualitative analysis of video narratives. Adolescents with CF were loaned video cameras and asked to “show us your life outside the hospital” and to “teach your healthcare team about your CF.” Four major themes were identified related to illness centrality: CF is Central, CF is Compartmentalized, CF is Integrated into Self Image, CF is Denied. Integration and compartmentalization often co-existed. Four themes emerged related to the role of CF in self-image and identity: (1) Valence (positive or negative); …


The Santa Clara, 2017-11-02, Santa Clara University Nov 2017

The Santa Clara, 2017-11-02, Santa Clara University

The Santa Clara

No abstract provided.


Diagnostic Divisions Of Eating Disorders: A Critical Analysis, Channah A. Leff Nov 2017

Diagnostic Divisions Of Eating Disorders: A Critical Analysis, Channah A. Leff

USF Tampa Graduate Theses and Dissertations

The objective of this thesis is to critically examine the diagnostic divisions of eating disorders as proposed within the Diagnostic and Statistical Manual of Mental Disorders (DSM-5). I focus on Anorexia Nervosa, Bulimia Nervosa, Binge Eating Disorder, and Other Specified Feeding or Eating Disorder (OSFED), although there were several new categories issued in 2013. Using person-centered ethnographic interviews, focus groups, participant observation, and autoethnography, I collected qualitative data to highlight how disordered eaters perceive themselves and their behaviors in relation to their diagnoses. I recruited participants in Boston, MA from Eating Disorders Anonymous (EDA), a decentralized network of support groups …


Retinitis Pigmentosa Genes Implicated In South Asian Populations: A Systematic Review, Sidra Zafar, Khabir Ahmed, Azam Ali, Rashid Baig Nov 2017

Retinitis Pigmentosa Genes Implicated In South Asian Populations: A Systematic Review, Sidra Zafar, Khabir Ahmed, Azam Ali, Rashid Baig

Section of Ophthalmology

Retinitis pigmentosa is one of the most prevalent causes of inherited retinal dystrophies worldwide. The widespread custom of consanguineous marriages in South Asian countries puts the population at risk for autosomal recessive disorders including retinitis pigmentosa. This systematic review was done between May and December 2015.A comprehensive literature search was carried out using MEDLINE and CINAHL databases and all relevant articles on causative mutations for non-syndromic Retinitis pigmentosa from 1999 till 2015 were included. Overall, 41 articles were identified involving 66 families; 28(68%)from Pakistan, 12(29%) from India and 1(2.4%) from Bangladesh. No data was available from the rest of countries …


2017 Program, Office Of Academic Affairs Oct 2017

2017 Program, Office Of Academic Affairs

Programs

Scholarship, creativity, innovation, and the many forms of collaborative engagement that shape faculty life and student learning are central to the mission of Eastern Illinois University. For that reason, our faculty, department chairs, college deans, the Provost, and the entire campus community celebrate the achievements and outstanding contributions of our colleagues and students to their disciplines and professions every year. And, as the following pages illustrate, faculty engaged in continuing scholarly and creative activities that have provided outstanding mentoring experiences for our undergraduate and graduate students.

In addition to recognizing faculty performances, shows, publications, grants and other professional efforts, the …


Dawson, Jim (Fa 1102), Manuscripts & Folklife Archives Oct 2017

Dawson, Jim (Fa 1102), Manuscripts & Folklife Archives

Folklife Archives Finding Aids

Finding aid only for Folklife Archives Project 1102. Paper titled “Ed Diddle Stories” in which Jim Dawson collects tales relating to former WKU Hilltopper basketball coach Edgar Allen Diddle. Paper is based on interviews with members of WKU faculty, all of whom played basketball under Coach Diddle.


Preliminary Findings Of A Technology-Delivered Sexual Health Promotion Program For Black Men Who Have Sex With Men: Quasi-Experimental Outcome Study, Charles H. Klein, Tamara Kuhn, Danielle Huxley, Jamie Kennel, Elizabeth Withers, Carmela Lomonaco Oct 2017

Preliminary Findings Of A Technology-Delivered Sexual Health Promotion Program For Black Men Who Have Sex With Men: Quasi-Experimental Outcome Study, Charles H. Klein, Tamara Kuhn, Danielle Huxley, Jamie Kennel, Elizabeth Withers, Carmela Lomonaco

Anthropology Faculty Publications and Presentations

Background: Human immunodeficiency virus (HIV) disproportionately affects black men who have sex with men (MSM), yet there are few evidence-based interventions specifically designed for black MSM communities. In response, the authors created Real Talk, a technology-delivered, sexual health program for black MSM.

Objective: The objective of our study was to determine whether Real Talk positively affected risk reduction intentions, disclosure practices, condom use, and overall risk reduction sexual practices.

Methods: The study used a quasi-experimental, 2-arm methodology. During the first session, participants completed a baseline assessment, used Real Talk (intervention condition) or reviewed 4 sexual health brochures (the standard of …


Teaching Students To Be Spiritually Sensitive: Learning From A Spirituality Course Evaluation, Ann M. Callahan, Kalea Benner Oct 2017

Teaching Students To Be Spiritually Sensitive: Learning From A Spirituality Course Evaluation, Ann M. Callahan, Kalea Benner

EKU Faculty and Staff Scholarship

Rationale

The way educators address spirituality can create a sense of community or social isolation. This necessitates a spiritually sensitive approach that enables students to build spiritual competence. Spiritual competence reflects an understanding of how spirituality shapes human behavior, how spiritual diversity manifests and can lead to risk for discrimination, and how to communicate spiritual sensitivity in professional relationships (NASW, 2008, 2007). Research shows that educators have helped students explore themselves and others spiritually (Barker & Floersch, 2010; Johnston, Mamier, Bahjri, Anton, & Petersen; 2008), but more research is needed on how self-reflection informs spiritual competence (Hodge & Derezotes, 2008). …


Student Pharmacists And Street Children: A Mutually Beneficial Relationship, Mario A. Hoyos, Monica L. Miller, Ellen M. Schellhase, C. Ryan Tomlin, Sonak Pastakia, Samuel Kimani, Tim Mercer Oct 2017

Student Pharmacists And Street Children: A Mutually Beneficial Relationship, Mario A. Hoyos, Monica L. Miller, Ellen M. Schellhase, C. Ryan Tomlin, Sonak Pastakia, Samuel Kimani, Tim Mercer

Purdue Journal of Service-Learning and International Engagement

The Tumaini Children’s Drop-In Center is a daytime drop-in center for the street children of Eldoret, Kenya. It is part of a partnership between the Purdue University College of Pharmacy, the Academic Model Providing Access to Healthcare program, Eldoret community members, and numerous individuals in both Kenya and the US. Through the efforts of local staff and Purdue student pharmacists, who work at the local hospital on an eight-week clinical rotation, the center has helped a population of nearly 400 local street children by providing a safe haven from life on the streets. Purdue student pharmacists aid the center by …


Water Supply In Developing Countries: Student Experiences In The Dominican Republic, Albert Alwang, Margaret Busse, Audrey Caprio, Marieke Fenton, Jason Hawes, Andrew Kanach, Autumn Mcelfresh-Sutton Oct 2017

Water Supply In Developing Countries: Student Experiences In The Dominican Republic, Albert Alwang, Margaret Busse, Audrey Caprio, Marieke Fenton, Jason Hawes, Andrew Kanach, Autumn Mcelfresh-Sutton

Purdue Journal of Service-Learning and International Engagement

In 2010, the United Nations established access to safe drinking water as a basic human right; however, many areas around the globe still lack access. The interdisciplinary service-learning course “Water Supply in Developing Countries” was established at Purdue in 2012 to address the complex issue of water insecurity around the world. Over the past five years, the course has produced teams involving students from nursing, engineering, agricultural economics, biology, and food science working together to develop sustainable, community-scale drinking water treatment systems. In partnership with Aqua Clara International, the student team in 2017 established a drinking water treatment system at …


Factors Associated To Acceptable Treatment Adherence Among Children With Chronic Kidney Disease In Guatemala, Brooke Ramay, Alejandro Cerón, Luis Pablo Méndez-Alburez, Randall Lou-Meda Oct 2017

Factors Associated To Acceptable Treatment Adherence Among Children With Chronic Kidney Disease In Guatemala, Brooke Ramay, Alejandro Cerón, Luis Pablo Méndez-Alburez, Randall Lou-Meda

Anthropology: Faculty Scholarship

Pediatric patients with Chronic Kidney Disease face several barriers to medication adherence that, if addressed, may improve clinical care outcomes. A cross sectional questionnaire was administered in the Foundation for Children with Kidney Disease (FUNDANIER, Guatemala City) from September of 2015 to April of 2016 to identify the predisposing factors, enabling factors and need factors related to medication adherence. Sample size was calculated using simple random sampling with a confidence level of 95%, confidence interval of 0.05 and a proportion of 87%. A total of 103 participants responded to the questionnaire (calculated sample size was 96). Independent variables were defined …


Evangelii Gaudium: A European Perspective, Salvatore Moccia Oct 2017

Evangelii Gaudium: A European Perspective, Salvatore Moccia

Journal of Vincentian Social Action

In order to understand the Apostolic Exhortation Evangelii Gaudium, we have to analyze the strategic roots of this Pope, a shepherd who lived his life with the smell of the sheep. Only if we recognize the “great enemy” we can fully understand all the Papal “No’s” of the Encyclical: no to an economy of exclusion, no to the new idolatry of money, no to a financial system which rules rather than serves, and no to the inequality which spawns violence. We believe that Pope Francis, with his Apostolic Exhortation Evangelii Gaudium, has updated most of the Franciscan reflections on the …


Delaware Health Sciences Alliance Global Health Symposium: Refugee And Immigrant Access To Care Locally And Globally Oct 2017

Delaware Health Sciences Alliance Global Health Symposium: Refugee And Immigrant Access To Care Locally And Globally

Global Health Events

Welcome to the 6th annual Global Health Symposium! As always, we are pleased to highlight the latest in our growing Global Health interests across the DHSA. The Delaware Health Sciences Alliance is a partnership of:

  • Christiana Care Health System
  • Jefferson Philadelphia University & Thomas Jefferson University
  • Nemours / Alfred I. duPont Institute for Children
  • University of Delaware


Auditory Object Perception: A Neurobiological Model And Prospective Review, Julie A. Brefczynski-Lewis, James W. Lewis Oct 2017

Auditory Object Perception: A Neurobiological Model And Prospective Review, Julie A. Brefczynski-Lewis, James W. Lewis

Clinical and Translational Science Institute

Interaction with the world is a multisensory experience, but most of what is known about the neural correlates of perception comes from studying vision. Auditory inputs enter cortex with its own set of unique qualities, and leads to use in oral communication, speech, music, and the understanding of emotional and intentional states of others, all of which are central to the human experience. To better understand how the auditory system develops, recovers after injury, and how it may have transitioned in its functions over the course of hominin evolution, advances are needed in models of how the human brain is …


Graduate Studies Newsletter, Graduate Studies Office Oct 2017

Graduate Studies Newsletter, Graduate Studies Office

Newsletters

Pg. 2 & 3 - Faculty Spotlight: Dr. Marisol Cortes Rincon

Pg. 5 - Important Dates and Deadlines

Pg. 6 - Graduate Student Orientation Recap

Pg. 7 - Thesis & Project Submission Process Guide

Pg. 8 - Graduate Student & Alumni Profiles


When The Books Hit Back: Perceived Stress In University Students, Henry Stoddard Oct 2017

When The Books Hit Back: Perceived Stress In University Students, Henry Stoddard

Independent Study Project (ISP) Collection

University students are a particularly high-risk population for mental illness due to high-stress levels. The university students of KwaZulu Natal, South Africa are no exception to that trend. This study surveyed and interviewed university students, and interviewed various mental health professionals from the Durban region of South Africa. The data was analyzed and used to better understand the current status of South African university students’ perceived stress, as well as the causes of their stress levels. Results showed no significant differences among demographic groups and perceived stress levels, but further research is needed to draw more reliable conclusions. In the …


The Latex Journey: A Narrative Approach To Exploring Condom Use, Stigma, And Education From The Perspective Of Women In Masxha, Kylie Yocum Oct 2017

The Latex Journey: A Narrative Approach To Exploring Condom Use, Stigma, And Education From The Perspective Of Women In Masxha, Kylie Yocum

Independent Study Project (ISP) Collection

Although the South African National Department of Health (NDOH) is spending increasing amounts of money on improving their HIV programs (including the rollout of new, scented condoms for their condom distribution program), the rates of condom use at last sexual encounter are declining. This inquiry focused on young women in the neighborhood of Masxha, Cato Manor, and their opinions surrounding how condoms are being used or misused, as well as the gender norms that perpetrate this (mis)use. This inquiry demonstrated the narratives of these young women on factors such as condom acquisition, gendered stigma, and condom education, including the Life …


Understanding Sanitation Preferences: An Exploratory Study In The Sirohi District Of Rajasthan, Karen Mac Oct 2017

Understanding Sanitation Preferences: An Exploratory Study In The Sirohi District Of Rajasthan, Karen Mac

Independent Study Project (ISP) Collection

Of all the countries in the world, India has the highest number of people practicing open defecation, causing adverse health outcomes from the unconfined spread of faecal matter. The Government of India is ambitiously aiming to end this practice through the construction of 12 million toilets by 2019, but historically, many toilets across India have gone unused. This study focused on understanding: (1) the reasons why people continue to openly defecate despite having toilets and (2) the requirements of a toilet that rural households would be willing to use. Along with 36 observations of household toilets, semi-structured group (n=8) and …


Women Of Leh Town, Ladakh: An Overview Of Perceptions Of Health, Health-Seeking Behaviors, And Access To Health Care, Sophia Marion Oct 2017

Women Of Leh Town, Ladakh: An Overview Of Perceptions Of Health, Health-Seeking Behaviors, And Access To Health Care, Sophia Marion

Independent Study Project (ISP) Collection

The following study seeks to investigate access to health care services and perceptions of health care among women residing in traditional farming communities around the Ladakh region, and to analyze perspectives on health, health-seeking behavior, and access to health care. This project was prompted by the fact that health care in this region is understudied. This study also focuses on marginalized communities including local women and immigrant women. Methods used for the collection of data were qualitative interviews conducted with 24 women, as well as an amchi worker, doctors, and informal and formal conversations with people from different nongovernmental Organizations …


When Knowledge Flows: A Case Study Of Village Health Workers’ Motivations In Jamkhed, Selaem Hadera Oct 2017

When Knowledge Flows: A Case Study Of Village Health Workers’ Motivations In Jamkhed, Selaem Hadera

Independent Study Project (ISP) Collection

Across the field of global health, there have been many attempts to cater to the health needs of the most marginalized populations. Community health workers (CHWs) are individuals that live in the communities they serve and are typically low-­‐income women with little to no formal education. After a period of training by their program, they enter their communities equipped as a bridge between the community and the health system. Although CHWs do play a substantial role in health delivery and education, the structure of CHW programs varies widely, but a common characteristic of these programs is that the CHWs are …


The Shifting Roles Of Dai Maas: An Intersection Of Healthcare And Female Empowerment In Rural Udaipur, Julie Morel Oct 2017

The Shifting Roles Of Dai Maas: An Intersection Of Healthcare And Female Empowerment In Rural Udaipur, Julie Morel

Independent Study Project (ISP) Collection

Traditional Birth Attendants (TBAs), known as dais in an Indian context, have historically served as women’s primary caregivers throughout their pregnancies and during childbirth in rural regions where access to formal healthcare institutions is nearly impossible. With a heavy reliance on traditional knowledge passed down through generations, dais have aided with home deliveries for millennia. Approximately 15 years ago, however, groups such as WHO, UNICEF, World Bank, and the UN began addressing India’s high maternal mortality rate (MMR), thereby instigating the discouragement of home deliveries in favor of the encouragement of institutional deliveries. Infrastructural changes were established to improve accessibility …


Managing Health In All The Helpers: A Survey Of Mental Health Services For Humanitarian Aid Workers, Erin Mercado Oct 2017

Managing Health In All The Helpers: A Survey Of Mental Health Services For Humanitarian Aid Workers, Erin Mercado

Independent Study Project (ISP) Collection

Humanitarianism has been a long-standing principle of helping those in need. However, the work of providing such assistance is not an easy feat. Humanitarian work is mentally taxing because of the high daily demands of the job as well as the potential for exposure to direct and secondary traumatization. These mental health risks can manifest into the mental health disorders if the stressors of the job are not well managed by individual aid workers and by the humanitarian organizations. The most common mental health disorders experienced by aid workers are depression, anxiety, burnout, and PTSD. Research into mental health and …