Digital Commons Network^™

Refractory Hypercalcemia In Sarcoidosis: Exacerbation By Thiazide Diuretics, Differentiation From Primary Hyperparathyroidism, And Possible Role Of Prolactin, A. M. Parfitt

Henry Ford Hospital Medical Journal

Hypercalcemia in a patient with sarcoidosis was made worse by a thiazide diuretic initially given to control hypercalciuria alone. The hypercalcemia was unusually resistant to corticosteroid treatment during the summer even after the thiazide diuretic had been discontinued. Lack of response to corticosteroid together with decreased tubular reabsorption of phosphate and increased tubular reabsorption of calcium suggested associated primary hyperparathyroidism, but PTH was undetectable by immunoassay, and nephrogenous cyclic AMP excretion was zero. Amenorrhea, galactorrhea and hyperprolactinemia were found to be due to a pituitary tumor which was removed. The experience with this patient suggests that: 1) exacerbation of hypercalcemia …

Effect Of Glucagon And Methylprednisolone On Pancreatectomized Recipients Of Whole Pancreas Allografts, Luis H. Toledo-Pereyra, Michael Zammit, Krishna D. Valjee

Henry Ford Hospital Medical Journal

Glucagon alone or in combination with methylprednisolone was an adequate therapeutic adjuvant for pancreatectomized recipients of whole pancreas allografts. All recipients were minimally immunosuppressed with azathioprine, 5.0 mg/K/day for three days, then 2.5 mg/K/day. The morphological, functional, and survival response after whole pancreas transplantation indicated a trend of improvement in the treated groups. Only the groups of dogs receiving glucagon alone or in combination with methylprednisolone survived more than two weeks after transplantation. This therapy has proven to be effective for whole pancreas transplantation.

Vital Signs, June, 1978,, Boonshoft School Of Medicine

Vital Signs

An eight page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, a research spotlight, alumni notes, and more.

Administrating A Residential Program For Persons With Developmental Needs, Jean W. Powers

Theses

The thesis, Administrating a Residential Program for Persons with Developmental Needs by Jean W. Powers, explores the principles and challenges of managing a residential facility for individuals with developmental disabilities. The author draws on her experience as the administrator of “The Ridge,” a residential program serving 60 individuals requiring out-of-home care and training due to developmental challenges. The paper emphasizes humanistic and participatory administration, guided by principles such as normalization, the developmental model, least restrictive alternatives, individual program plans, and resident rights.

The principle of normalization advocates treating residents as normally as possible by fostering independence, promoting age-appropriate behaviors, and …

Influence Of Denervation And Hemithyroidectomy On The Age Related Increase In The Number Of Calcitonin-Containing Cells In Mouse Thyroid, Nualnoi Wechbanjong

Loma Linda University Electronic Theses, Dissertations & Projects

It has been concluded from this study that nerve fibers in the superior laryngeal nerves have an influence on the development of C-cells in the mouse thyroid. This conclusion is based on the results of two types of investigation. The first is an analysis of the effect of age on the number of C-cells and the second is an investigation of the influence of denervation and hemithyroid-parathyroidectomy on the age related changes in C-cells numbers.

I. The distribution and c011centraticn of C-cells in mouse thyroid at various ages.

Serial 6 µm sections of thyroid glands from Swjss Webster mice at …

Effects Of Trypanosoma Musculi Kendall, 1906 Immune Serum On The Reproduction Of Trichinella Spiralis (Owen, 1835) Railliet, 1896 In Mice, Samuel L. Chafin

Loma Linda University Electronic Theses, Dissertations & Projects

The possible effects of ablastin, a reproduction-inhibiting antibody which is produced during the infection of the blood parasite, Trypanosoma musculi in the mouse, were investigated by fractionating the parasite into a supernatant fraction (designated as Group A test mice) and a pellet fraction (Group B test mice). These groups A and B mice were injected with the respective fractions, plus Freund’s Complete Adjuvant (FCA). Control mice were injected with FCA only. Sera from these three groups of mice were removed after the Group A and Group B mice were shown to be negative to T. musculi challenge, and Group A …

Comparison Of Root Surfaces In Endodontic Lesions, Periodontic Lesions And Normal Human Teeth, Robert W. Hanson

Loma Linda University Electronic Theses, Dissertations & Projects

The healing potential of an endodontic lesion is usually greater than a periodontic lesion (Simon et al. 1972; Hiatt 1977). Periodontal regeneration places particular emphasis on the soft tissue-tooth interface (Stahl 1977). This interface was examined in fifteen extracted human teeth.

The teeth were divided into three groups: (1) periapical lesions, (2) periodontal lesions, and (3) healthy periodontal tissue. Criteria were established for each group. Freshly extracted human teeth meeting the criteria were fixed in gluteraldehyde or paraformaldehyde. The teeth were then selected for surface observation or cracked for cross sectional examination. The teeth were post fixed, dehydrated, and coated …

Front Matter, Vol. 20 No. 5

Brigham Young University Science Bulletin, Biological Series

No abstract provided.

Noradrenergic Neurons Of The Rat Locus Coeruleus : Anatomical, Physiological And Pharmacological Studies, Jesse Michael Cedarbaum

Yale Medicine Thesis Digital Library

n/a

Neutron Diffraction Analysis Of The Structure Of Rod Photoreceptor Membranes In Intact Retinas, Mark Jay Yeager

Yale Medicine Thesis Digital Library

No abstract provided.

Responsiveness In Newborn Infants Of Normal Weight And Overweight Parents, Robert Michael Milstein

Yale Medicine Thesis Digital Library

No abstract provided.

Effect Of Time And Diet On The Immune Status Of Mice Challenged With Herpes-Transformed Cells, Daila S. Gridley

Loma Linda University Electronic Theses, Dissertations & Projects

Human Herpes simplex virus type 2 (HSV 2)-transformed Balb/c mouse cells (H238 cells) are malignant in Balb/c mice. The immune stratus of mice bearing H238 cell-induced tumors was studied and changes in immune response with time and with altered diet of the mice were measured.

In the experiments dealing with the status of immunity with time after tumor cell injection, mice were fed Purina Laboratory Chow (P.L.C.), injected with H238 cells, and sacrificed three to eight weeks post-injection. In the diet experiments, groups of mice were fed either P.L.C. or one of six equicaloric diets, consisting of low or high …

The Effect Of Perceptual Set On Listener Judgments Of Voice Quality Deviations, Patricia M. Hansen

Loma Linda University Electronic Theses, Dissertations & Projects

The purpose of this study was to test the possible influence of perceptual set on listeners' judgments of voice quality deviations. Perceptual set was created by instructions given to an experimental group which limited their choices, thus encouraging a particular response. The effect of set on the overall performance of the group, on backward versus forward voice samples and on the level of experience of the listener were all investigated.

The sample for this study was comprised of 24 students of speech pathology and audiology. The subjects were divided into matched experimental and control groups and asked to listen to …

The Effect Of The Warm Water Bath On Axillary Temperature In Normal Newborns, Ann J. Morton

Loma Linda University Electronic Theses, Dissertations & Projects

The purpose of this study was to compare the effects of the warm water bath and the radiant heater on the axillary temperatures of normal newborns. The sample group consisted of thirty newborns--15 babies placed into the water bath in Group I, and 15 babies placed under the radiant heater in Group II. Birth weights were between 6.25 and 8.75 pounds, gestational ages between 37 and 41 weeks, and 5-minute Apgar scores were 8 or more. The maternal temperatures, taken within two hours before birth, ranged between 97 and 99 degrees. All infants were born by spontaneous or low-forceps vertex …

The Development And Characterization Of Markers For The Variable Regions Of Mouse Dnp Binding Antibodies, Jerome Bernard Zeldis

Yale Medicine Thesis Digital Library

No abstract provided.

The Effect Of High Protein, Low Pyridoxine Diet On Calcium Retention In Rats, Julia S. Bottom

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The effect of increasing the dietary protein and pyridoxine level on calcium balance and bone strength was studied in growing and adult rats. The loss of calcium due to urinary excretion of o-phosphoryl-ethanolamine on a high protein diet was also examined.

Three studies were conducted. In the first adult male rats were fed 40% protein diets with high or low pyridoxine or a low protein, low pyridoxine diet. Calcium balance and femur bending stress were determined. In the second study male weanling rats were given either 10 or 63% protein with 0.40 or 0.73% pyridoxine. Calcium and phosphorous balances were …

The Stability Of Expanded Mandibular Canines, Premolars, And Molars Concomitant With Rapid Midpalatal Expansion, Ralph S. Kurti

Loma Linda University Electronic Theses, Dissertations & Projects

The view of not expanding mandibular canines to accommodate incisor crowding because of the fear of relapse of of the incisors has been generally accepted in orthodontics for many years. Most studies that have investigated expanded mandibular canine stability have concluded that they could not be permanently expanded to any degree. By adding another variable (rapid midpalatal expansion) to canine expansion it was thought that this might possibly increase canine expansion stability.

The purpose of this research was to determine if the stability of the expanded canines through 1st permanent molars was enhanced by concomitant rapid expansion of the midpalatal …

Glutamine Transport, Metabolism, And Ammoniagenesis In Rat Kidney, Jose Punnakudyil George

Biomedical Sciences ETDs

Thie purpose of these studies was to clarify the functional significance of glutamine penetration and metabolism in postnatal increas1e in renal a1T111onia production using rat kidney slices .

Glutamine uptake, metabolism and ammoniagenesis were studied in kidney slices isolated from mature, gonadectomized males and females, and newborn rats in the presence of varying concentrations of glutamine. Slices isolated from mature intact females showed significantly higher conversion of ¹⁴C-glutamine into ¹⁴co₂ and NH₃ without any change in total uptake compared to all other experimental groups. Ovariectomy reduced CO₂ and NH₃ production without any effect on …

Monitoring Of Cortical Mitochondrial Respiration During Microanastomosis, George Austin, Britton Chance, William Hill, Clyde Barlow

The Dr. George M. Austin Neurology Research Collection

Monitoring of Cortical Mitochondrial Respiration During Microanastomosis. George Austin, M.D., Britton Chance, Ph.D., William Hill, M.D., Clyde Barlow, Ph.D.

Section of Neurological surgery, Loma Linda University School of medicine, Loma Linda, California, and Johnson foundation for Biophysics and Biochemistry, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania

April 1978. 2 pg. Conference presentation

Ariel - Volume 8 Number 5, R. S. Moberg, George Greasy, Neeraj Kanwal, Nicholas Tepe, Patrick Sokas, Jim Spigel, Jim Sechler, Martin Trichtinger, Shahab Minassian, Doug Jenkins

Ariel

Executive Editor

James W. Lockard. Jr.

Business Manager

Neeraj K. Kanwal

University News

Martin Trichtinger

World News

Doug Hiller

Opinions

Elizabeth A. McGuire

Features

Patrick P. Sokas

Sports Desk

Shahab S. Minassian

Managing Editor

Edward H. Jasper

Managing Associate

Brenda Peterson

Photography Editor

Robert D. Lehman, Jr.

Graphics

Christine M. Kuhnle

The Effects Of Body Size, Hair And Brown Adipose Tissue Upon Fever In The Rabbit, Reginald L. Dean

Masters Theses

No abstract provided.

Jefferson Alumni Bulletin – Volume Xxvii, Number 3 Spring 1978

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume XXVII, Number 3 Spring 1978

Mutter Museum, Page 2

Hemophilia: The Disease of Royal History, Page 9

Students Take Parents to School, Page 15

Jefferson Scene, Page 18

Class Notes, Page 24

Obituaries, Page 38

Front Matter, Vol. 2

Great Basin Naturalist Memoirs

No abstract provided.

Effect Of Perfusate Osmolarity On Hearts Preserved Under Hypothermic Pulsatile Perfusion For 24 Hours, Luis H. Toledo-Pereya, Manuel Chee, Richard C. Lillehei

Henry Ford Hospital Medical Journal

Canine hearts preserved under hypothermic pulsatile perfusion (24 hours) with an osmolarity of 340 mOsm/L had better preservation and transplantation response than hearts perfused at an osmolarity of 310 and 270 mOsm/L. The hearts perfused at 340 mOsm /L survived an average of 22.6 days after transplantation. This survival was significantly (p>0.05) better than that observed after fresh transplantation (13.4 days average). Hearts perfused at 270 mOsm /L had a significantly (p>0.05) lower survival after transplantation (5.8 days average) than the fresh allografts or the hearts perfused at 310 or 340 mOsm / L. Similar survival times were …

Full Issue, Vol. 2

Great Basin Naturalist Memoirs

No abstract provided.

End Matter, Vol. 2, Index

Great Basin Naturalist Memoirs

No abstract provided.

The Quantitative Determination Of 3-Oxo-Bile Acids, W. T. Beher, G. J. Lin, J. Sanfield, S. Stradnieks

Henry Ford Hospital Medical Journal

A new method for the rapid quantification of 3-oxo-bile acids has been developed. From 5 to 120 μg of oxo-acid in aqueous or ethanolic media are reduced with sodium borohydride. The resulting 3α- and 3β-hydroxy acids are then oxidized in a reaction catalyzed by 3-hydroxysteroid dehydrogenase, during which nicotinamide adenine dinucleotide (NAD) is reduced to NADH. The absorbance of the reaction mixture is determined at 340 nm and is directly proportional to the amount of 3-oxo-acid in the original sample. The method is fully compatible with that used in determining 3α-hydroxy-bile acids.

End Matter, Vol. 2

Great Basin Naturalist Memoirs

No abstract provided.

Newsletter, Volume 23, Number 02, March - April 1978, Louise C. Strong Md, William Au Phd, Sen Pathak Phd, Cheryl Collie Bs

Newsletter: A Report to Physicians of Texas Archives

• NIH Chimpanzee Grant
• National Large bowel cancer Project Renewed
• Manual for Staging of Cancer Published
• Reproductive Considerations for Young Cancer Patients, Louise C. Strong, MD
• Genetic Marker for Breast Cancer
• Ernst W. Bertner Memorial Award
• Cytogenetic Toxicity of Gentian Violet and Crystal Violet, William Au, PhD, Sen Pathak, PhD, Cheryl Collie, BS, T.C. Hus, PhD
• AHH Enzyme Activity Related to Lung Cancer
• MDAH Establishes Nutrition Classes

Phytate Extraction And Stimulation Of Phytase By Zn & Mg In Seeds, Sandra Gin-San Chow

Loma Linda University Electronic Theses, Dissertations & Projects

Almonds, peanuts, mung beans and soy beans were soaked in distilled water for 0, 2, 6, 18 and 24 hours, and the phytate in the seeds and in the soak water was quantitatively analyzed. A comparison of phytate content was made after the seeds were soaked in 0.01 N HCl or in saturated NaHco 3. The seeds soaked in distilled water served as controls. The effects of zinc and magnesium on stimulation of phytase in seeds were determined by comparing the quantity of substrate (phytate) with that of the control group.

The method for analyzing the phytate content was based …