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Winter 1981, Southwestern Oklahoma State University

The Sig

The Sig Newsletter from the Southwestern Oklahoma State University College of Pharmacy - Winter 1981

Colonial Cultivation And Concoctions, Sara Jones Gomberg

MCV/Q, Medical College of Virginia Quarterly

Have you ever wondered how to increase the value of your property? One way would be to include a well-cultivated herb garden, that is if you were a seventeenth-century colonist. Not only were the herbs much sought after for their culinary uses but also for their medicinal properties. Today’s medical library may not include a collection of botany books, yet botanical knowledge was a large part of early medical training and the mainstay of the “cavalier concoctions” used by colonists for medical treatment.

1981 Apothecary, Southwestern Oklahoma State University

Apothecary

THE APOTHECARY would like to congratulate the Seniors on the completion of five years of hard work. We have learned much about our profession and accept the challenges of a professional pharmacist - to be leaders in the advancement of our profession.

External Versus Internal Locus Of Control In Longterm Drug Abusers, Heidi Knipe

Theses Digitization Project

No abstract provided.

Outlook Magazine, Summer 1981

Outlook Magazine

No abstract provided.

Outlook Magazine, Winter 1981

Outlook Magazine

No abstract provided.

Outlook Magazine, Autumn 1981

Outlook Magazine

No abstract provided.

Outlook Magazine, Spring 1981

Outlook Magazine

No abstract provided.

Injuries To Birds Of Prey Caught In Leghold Traps, Katherine Durham

International Journal for the Study of Animal Problems

One hundred and seventy-three raptors, including 32 Bald Eagles, have been treated for trapping injuries at the University of Minnesota Raptor Research and Rehabilitation Program since 1972. These birds were primarily caught in "open" bait leghold sets incidental to furbearer trapping in the Minnesota region. The differential outcome of the injuries concerning crippling or mortality is presented for large versus small raptors, toe versus leg injuries, and leg fracture versus soft tissue damage only. There is only limited potential for mitigating the effects of trapping injuries.

The Psychology Of Euthanizing Animals: The Emotional Components, Charles E. Owens, Ricky Davis, Bill Hurt Smith

Human and Animal Bonding Collection

The emotional effects of euthanizing unwanted animals on professional animal control personnel are examined using written statements of and discussions among twenty-six euthanasia technicians at a workshop during a national session of the Animal Control Academy (Tuscaloosa, AL]. Emotional conflicts arise .in significant part from the dilemma that the same public which is responsible for the problem of unwanted animals also has a markedly negative perception of euthanasia, and by extension, of those who perform euthanasia. During discussions, the euthanasia technicians revealed a variety of strategies for coping with feelings of isolation, alienation and sorrow. These included intellectualization, avoidance of …

Ethical Concerns In Primate Use And Husbandry, Ardith A. Eudey

Experimentation Collection

Subsequent to World War II, a dramatic increase occurred in the utilization of nonhuman primates in biomedical and psychological research and industry. At the same time field studies on the ecological and social behavior of natural populations of primates also increased, making possible more realistic assessments of both the behavioral potentiality of primate populations and their conservation status. In spite of the growing body of information indicating the endangered or threatened status of most species, many laboratory workers and planning agencies continue to regard primates as renewable resources, even seeking to bypass protective legislation in habitat countries to obtain them. …

Biomedical Research And Animal Welfare: Traditional Viewpoints And Future Directions, Franklin M. Loew

Experimentation Collection

It has been twenty years since C.P. Snow first presented the concept of "The Two Cultures"; referring to the "culture" of scientists and the "culture" of literary intellectuals (mainly writers), Snow said (1969):

... constantly I felt I was moving among two groups- comparable in intelligence, identical in race, not grossly different in social origin, earning about the same incomes, who had almost ceased to communicate at all, who in intellectual, moral and psychological climate had so little in common ...

In some ways, "Two Cultures" goes far to characterize the current state of affairs surrounding those whose scientific endeavors …

Conversation With Henry Spira: Draize Test Activist, Lynne Harriton

Interviews

No abstract provided.

Mcv/Q, Medical College Of Virginia Quarterly, Vol. 15 No. 3

MCV/Q, Medical College of Virginia Quarterly

No abstract provided.

Medicine In Retrospect

MCV/Q, Medical College of Virginia Quarterly

The following is a transcript of an informal talk by Drs. Kinloch Nelson and Charles M. Caravati, presented in 1974 to the School of Medicine of the Medical College of Virginia, Health Sciences Division of Virginia Commonwealth University, Richmond, Virginia.

Recent Advances In Cancer Chemotherapy, Robert B. Diasio

MCV/Q, Medical College of Virginia Quarterly

The present state of cancer chemotherapy can be reviewed in light of selected basic principles with an acknowledgement of the role of established chemotherapeutic agents. Four chemotherapeutic agents recently approved for clinical use and their impact when used in combination regimens should be examined. Several important concepts influencing chemotherapy in the 1980s include the use of chemotherapy in the adjuvant setting, the use of hormonal receptor data in planning therapy, and the use of in vitro tests on tumor specimens to predict tumor sensitivity to cancer chemotherapy drugs (prior to administration of these potentially toxic drugs to a particular patient). …

Tapping The Tube, Sara Kaltreider

MCV/Q, Medical College of Virginia Quarterly

Before percussion and mediate auscultation were discovered, methods of physical examination – in particular chest examination – were limited. Only observation was used with any regularity. From the time of Hippocrates, palpation and direct auscultation had been used sporadically to detect heartbeats but had not proved to be of practical value because clinicopathological correlation had not yet been established. At last, when a new method called percussion was conceived by Auenbrugger in 1761, it was ignored for almost forty years. Not until the French School evolved did percussion become established, largely through Corvisart, Napoleon’s private physician. Coincident with the revival …

Namru-3 Translations Of Parasite Literature From Russian, French, Japanese, Etc. Into English (1921-1981) T1401-T1500, United States Naval Medical Research Unit Number Three, Cairo, Medical Zoology Department

United States Naval Medical Research Unit 3: Publications

T1401. TRANSLATION FROM RUSSIAN. L'VOV, D. K., GROMASHEVSKY, V. L., SIDOROVA, G. A., TSIRKIN, Yu. M. CHERVONSKY, V. L. GOSTINSHCHIKOVA, G. V. and ARISTOVA, V. A. (1971). Isolation of a new arbovirus Baku of Kemerovo group from argasid ticks Ornithodoros coniceps. in Azerbaijan. Vop. Virus., 16(4):434-437.

T1402. TRANSLATION FROM RUSSIAN. ALEKSANDROV, Yu. V., KORYAGIN, V. L. and YOVAL'CHUK, Zh. T. (1970). Observations on ecological biological properties of Hyalomma plumbeum ticks in eastern Crimea. Tezisy Dokl. 2. Akarol. Soveshch., (1):22-24.

T1403. TRANSLATION FROM RUSSIAN. MATEVOSYAN, K. Sh., KARASEVA, P. S. and SEMENOV, B. F. (1974). Study of potential arbovirus foci in …

Kronos [1981], State University Of New York At Stony Brook, School Of Medicine

Kronos (School of Medicine)

This edition of Kronos, published in 1981, is the official yearbook of the State University of New York at Stony Brook, School of Medicine. Hard-bound.

Role Of The Arachidonic Acid Metabolites, Thromboxane A2 And Prostacyclin, In Shock Induced By Intraabdominal Sepsis, Robert Raymond Butler

MUSC Theses and Dissertations

A rat fecal peritonitis model of acute intraabdominal sepsis was investigated in order to evaluate the potential role of arachidonic acid metabolites in septic shock. Immunoreactive (i) Thromboxane (Tx) B2, the stable metabolite of TXA2' and i6-keto-PGF1α, the stable metabolite of prostacyclin, were measured by radioimmuonassay. plasma levels of iTXB2 rapidly increased from non-detectable (ND< 200 pg/ml) to 1,066 -/+ 194 pg/ml (N=14) 1 hour after feces injection. iTxB2 then increased to 1,695 -/+ 218 pg/ml (N=16) at 4 hours and remained unchanged through 6 hours. Plasma i6-keto-PGF1α increased from ND to 3,777 -/+ 414 pg/ml (N=16) at 1 hour. Four hours after feces, i6-keto-PGF1α levels rose to 6,945 -/+ 732 pg/ml (N=16) then continued to rise to 9,465 -/+ 792 pg/ml (N=7) at 6 hours. Either essential fatty acid deficiency (arachidonic acid depletion) or indomethacin pretreatment (cyclooxygenase inhibition) significantly decreased (P< 0.01) the elevations of plasma iTxB2 and i6-keto-PGF1α associated with fecal peritonitis. Thrombocytopenia occurred within 6 hours after injection of feces and was significantly improved (P< 0.05) by indomethacin. Elevated fibrin degradation products at 6 hours (18 -/+ 3 µg/ml) were significantly reduced in essential fatty acid deficient (7 -/+ 2 µg/ml; P< 0.05) and indomethacin treated (4 -/+ 0.7 µg/ml; P< 0.01) rats. Survival time (8.6 -/+ 0.2 hours) was significantly enhanced by essential fatty acid deficiency (10.2 -/+ 0.4 hrs; P< 0.01) or indomethacin pretreatment (13.3 -/+ 0.6 hrs; P< 0.01). These studies show that fecal peritonitis is associated with increased synthesis of thromboxane A2 and prostacyclin and suggest that these arachidonic acid metabolites may play a role in the pathophysiology of septic shock. To evaluate the pathogenic role of thromboxane (Tx) and prostacyclin (PGI2) in septic shock, the protective efficacy of the Tx synthetase inhibitor, 7(l-imidazolyl) heptanoic acid (7-IHA) and the cyclooxygenase inhibitor, ibuprofen, were assessed during fecal peritonitis in the rat. 7-IHA (60 mg/kg) administered ip 30 minutes prior to feces significantly reduced the plasma level of iTxB2 to ND (P< 0.01) at 1 hour and to 508 -/+ 56 pg/ml (P< 0.01) at 4 hours after injection of feces. In contrast, the levels of i6-keto-PGF1α, the stable metabolite of PGI2 were significantly elevated by 7-IHA pretreatment from septic control levels to 5,185 -/+ 467 pg/ml (P< 0.05) at 1 hour. Plasma i6-keto-PGF1α at 4 hours in 7-IHA treated rats (5,503 -/+ 665 pg/ml) was not different from untreated controls. Ibuprofen (5 mg/kg) administered ip 30 minutes prior to feces significantly decreased both iTxB2 and i6-keto-PGF1α plasma levels to 729 -/+ 99 pg/ml and 1,327 -/+ 251 pg/ml, respectively (P< 0.05) at 4 hours. Survival associated with fecal peritonitis was not altered by 7-IGA pretreatment, but was significantly improved (P< 0.05) in ibuprofen treated rates. Fibrin degradation products were also significantly decreased (P< 0.05) by 7-IHA pretreatment. These results suggest that TxA2 may contribute to the coagulopathies seen in septic shock and that PGI2 may be associated with terminal pathophysiologic events. The final phase of this project investigated the possible synergistic benefit between an antibiotic, gentamicin (GENT), and reduction of arachidonic acid metabolism by pre-administration of indomethacin (INDO) or essential fatty acid (EFA) deficiency. GENT significantly increased mean survival time to 23.8 -/+ 2.6 hours (N=16; P< 0.01). GENT + INDO or GENT + EFA deficiency further improved mean survival time and produced long term survivals (>48 hrs) of 35% (N=17) and 30% (N=7) respectively (P< 0.01 compared to GENT). GENT pretreatment did not significantly alter plasma iTxB2 levels, however, it selectively decreased i6-keto-PGF1α. For example, i6-keto-PGF1α decreased from 9,465 -/+ 792 pg/ml (N=7) to 2,096 -/+ 1174 pg/ml (N=5; P< 0.01) at 6 hours after induction of fecal peritonitis. GENT + INDO pretreatment significantly decreased both iTxB2 and i6-keto-PGF1α to ND (P< 0.01). Pretreatment with GENT alone did not reduce fibrin degradation products. These findings are consistent with the concept that TxA2 may play a role in consumptive coagulopathies and PGI2 may be associated with the terminal hypotension seen during septic shock. The effect of GENT on TxA2 and PGI2 production was investigated further. GENT had no observable effect on in vitro endotoxin stimulated production of these arachidonic acid metabolites by cultured rat peritoneal macrophages. GENT significantly reduced the plasma levels of iTxB2 and i6-keto-PGF1α during endotoxin induced shock in rats. These observations support a complex interaction of bacteria, endotoxin, host tissues, and gentamicin with the possible involvement of undescribed mediated factors.

A Third Variable In Obesity: The Effects Of Brown Adipose Tissue On Thermogenesis, Mark R. Mcminn

Faculty Publications - Doctor of Psychology (PsyD) Program

Approaches to weight management which consider only energy intake and/or expenditure do not consistently lead to favorable outcomes. A third variable, thermogenesis, must also be considered in a comprehensive understanding of obesity· Three types of thermogenesis have been outlined-shivering thermogenesis, nonshivering thermogenesis (NST), and diet-induced thermogenesis (DIT). The latter two types of thermogenesis, NST and DIT, may share a common biochemical mechanism which leads to heat production in brown adipose tissue (BAT) which is unchecked by energy needs. Four categories of studies are reviewed which implicate BAT as an important factor in DIT and point to commonalities in NST and …

An In Vivo Study Of Rabbit Oviductal Motility As Recorded Utilizing A Microminiature Extraluminal Force Transducer, William R. Anderson

MUSC Theses and Dissertations

A microminiature force transducer has been developed and used to record both acutely and chronically the motility of the rabbit reproductive tract. This device, which is comprised of two matched piezoresistive silicon sensors bonded to a titanium beam strip, is durable, physically stable, and highly sensitive to bending forces (gage factor, 140). The reproductive function of 26 rabbits in which two such devices were chronically implanted on the right isthmus was examined in detail. The animals in which these devices were implanted healed quickly with no evidence of infection or other pathological change. No alterations were noted between right (implanted) …

Drugs And The Performance Horse, Thomas Tobin

Veterinary Science Books

This book presents an unprecedented account of the actions, effects and consequences of drug use in performance horses. Written for horsemen by a veterinarian and world authority on equine drugs, it deals with all classes, types, and uses of drugs. Professor Tobin describes how the drugs act, how they influence performance, and the problems they may cause. He explains the drug testing process and presents the best information available on the clearance times for drugs in horses. The text is written in plain language and with a touch of humor.

The Effect Of Chronic Ethanol Administration On Organelles Involved In Rna/Protein Synthesis In Mature And Immature Hamster Neurons, Carole R. Dunmire-Graff

Dissertations

No abstract provided.

The Relationship Between Type A Coronary-Prone Behavior Pattern, Achievement, And Life Satisfaction, Larraine A. Felland

Theses and Dissertations

This study examined the relationship between Type A coronary-prone behavior pattern, academic achievement and life satisfaction. The subjects were 87 undergraduates selected for their extreme scores on the Jenkins Activity Survey, Form T. There were 41 Type As and 46 Type Bs. Along with the Jenkins Activity Survey, Form T the participants were administered a life satisfaction survey similar to Soper's (1979) and their official academic gradepoint average was obtained from the Academic Records office. A point-biserial correlation indicated that there was a significant (p

The various relationships and their possible explanations and indications were discussed in depth. Significance of …

Cenobium 1981, Louisiana State University And Agricultural And Mechanical College, School Of Veterinary Medicine, Joanne Maki

Cenobium Yearbook

Cenobium began publication in 1977 and continued through 1990. Produced by students, the yearbooks are a chronicle of the daily life and the special events experienced by veterinary students at the LSU School of Veterinary Medicine.

A Strain Gauge Comparison Of Torquing Forces Generated By Orthodontic Archwires, William R. Caryl Jr.

Master's Theses

No abstract provided.

1981 Annual Reports And Resolutions, American Dental Association

ADA Transactions

This item is part of the Annual Reports and Resolutions subtitle of the ADA Transactions, a serial publication of the annual activities of the ADA House of Delegates (HOD)/Board of Trustees (BOT) made up of three separate subtitles: Annual Reports and Resolutions, Supplements, and Transactions. Generally, the ADA Transactions are published in multiple volumes throughout the year. Older versions include reports from all departments as subsections, while more recent versions include only those of councils, commissions, and committees.

Mobbing Calls Of The Phainopepla, Daniel W. Leger, Laura F. Carroll

Department of Psychology: Faculty Publications

When mobbing potential predators, male Phainopeplas (Phainopepla nitens) utter smoothly upswept vocalizations, unlike the harsh, staccato mobbing calls of other birds and mammals. A Phainopepla repeats this call as it approaches the bottom of its diving arc over the predator. We suggest that these calls do not serve to attract additional mobbers to the scene. Rather, they appear to emphasize the diving attacks directed toward the predator.

Isolation Of ��₂-Microglobulin From Miniature Swine Area, Barbara A. Roach

Yale Medicine Thesis Digital Library

No abstract provided.