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What's Happening: June 10, 1987, Maine Medical Center

What's Happening

No abstract provided.

Localization Of A Radiolabeled Monoclonal Antibody To Calcitonin In Rat Medullary Thyroid Carcinoma Allografts, Naguib A. Samaan, Kuo-Pao Yang

Henry Ford Hospital Medical Journal

A radiolabeled anticalcitonin monoclonal antibody (MoAb) was testedfor tumor-localizing capability in WAG/Rij rats allografted with cultured medullary thyroid carcinoma cells (line 44-2). 131I-labeled anticalcitonin IgG was taken up by the tumors in a time-dependent and dose-dependent manner. Tumor tissue uptake of the injected MoAb was 0.7 to 1.3%/g of tumor tissue when tested with a dose range of 40 lo 250 μg/kg of body weight. Distribution ratios of the radiolabeled MoAb were 1.2:1 for tumor-to-blood and 2-20:1 for tumor-to-organs. In rats injected with control IgG, disiribution ratios of radioactivity were 0.4:1 for tumor-to-blood, and 0.6-2:1 for tumor-to-organs. These results suggested …

Serial Casting: Clinical Applications For The Adult Head-Injured Patient, Cynthia Zablotny, Maureen Forte Andric, Charlotte Gowland

Faculty Publications - College of Physical Therapy

Serial casting has been used for over a decade to manage soft tissue contractures in patients with traumatic head injuries. Its use has also extended to the prevention of contractures in extremities exhibiting potentially deforming spasticity. This article will review the causes of soft tissue contractures and discuss how serial casting can manage such deformities. It will also identify how a serial casting program can be modified and integrated with other therapeutic efforts as the head-injured patient progresses physically and cognitively. Finally, it will address the timing and priority of casting in the patient's overall program.

A Non-Human Primate Model For Studying Corticotomy-Facilitated Orthodontic Tooth Movement, R. David Rynearson

Loma Linda University Electronic Theses, Dissertations & Projects

This study was undertaken to test the hypothesis that a corticotomised tooth moves as a tooth-bone unit when under orthodontic force. A non-human primate model was designed to test the hypothesis. The non-human primate selected was Macaca fasicularis. Three adult males with erupted third molars were chosen so that extrapolation could be made to the adult human. The methods employed included the following: 1) Each animal had one treatment quadrant and one control quadrant per arch; 2) Pre-op and post-op study models were made; 3) All 2nd premolars, 2nd molars, and 3rd molars were banded; 4) A full-thickness flap …

Magnetic Forces For Intrusion Of Buccal Segments In Dolichofacial Individuals With Anterior Open Bite : A Report Of Six Cases, Rosa Maria I. Reimann-Blaseio

Loma Linda University Electronic Theses, Dissertations & Projects

The correction of anterior open bite in dolichofacial individuals with magnetic forces has been studied. The attempt was made to intrude buccal segments by using interarch magnets set in repulsion in order to correct the anterior open bite of six dolichofacial patients. It was expected to intrude the posterior sections with these magnetic forces, to autorotate the mandible and to close the anterior open bite by decreasing the lower facial height and rotating the facial axis closed. The magnets were placed in each arch only on those teeth that needed intrusion, mainly second premolars and existing molars, for a period …

A Study Of The Relationship Between Incisor Intrusion And Root Resorption, W. Michael Mcfadden

Loma Linda University Electronic Theses, Dissertations & Projects

This study examined the relationship between maxillary and mandibular incisor intrusion and root resorption. Age, sex, facial type, treatment time, extraction versus non-extraction therapy, width of the symphysis, and the angle of the incisors to skeletal reference planes were also studied for their relationship to intrusion and root resorption. Thirty-eight cases treated with utility arches for intrusion were selected. Root shortening was found to average 1.84 mm for maxillary incisors and 0.61 mm for mandibular incisors. Intrusion of incisors in a population that exhibited growth was found to be one of "holding against growth". No relationship was found to exist …

Case-Control Study Of Vitamin A Intake And Colorectal Cancer In Seventh-Day Adventists, John William Morgan

Loma Linda University Electronic Theses, Dissertations & Projects

Colorectal cancer is the second most common cause of cancer deaths in Americans; producing approximately 60,000 deaths in Americans each year. Studies of high and low risk populations have suggested a dietary etiology for colorectal cancer, although investigations of specific dietary factors have produced inconsistent results.

Population based studies of California Seventh-day Adventists demonstrate dietary variety regarding factors suspected as important in the etiology of colorectal cancer. These studies document a substantially reduced mortality and incidence from colorectal cancer in Seventh-day Adventists when compared to other California Populations. Although specific reasons for this difference remain obscure, the 'Unique lifestyle and …

An Ethical Analysis Of Alternatives In Childbirth, William K. Faber

Loma Linda University Electronic Theses, Dissertations & Projects

This discussion concerns the ethical aspects of decisions regarding the various options of place, attendant and method for the actual delivery of infants. It focuses on the moral claims of childbearing women and fetuses and the roles of health care providers and society at large during the brief, but significant, transitional period between the state of pregnancy and the state of separate parent-child relations. The author's thesis is divided into two major components. The first component is that certain alternatives to what has become the typical U.S. childbirth experience are, under appropriate circumstances, safe and provide benefits which justify their …

Identification Of Actinobacillus Spp Cell-Surface Antigens Using Monoclonal Antibodies, Kall S. Symons

Undergraduate Honors Capstone Projects

Though a senior project is required for graduation from U.S.U. with the Honors Program, there are no written guidelines describing the requirements of a U.S.U. Honors Senior Project. This proposal seeks to show how the present research project from the College of Agriculture should meet the intended project requirements of the Honors Director.

Treatment Of Periodontal Furcation Defects, Bernard Gantes

Loma Linda University Electronic Theses, Dissertations & Projects

This report provides an abbreviated review of the literature on treatment and prognosis of periodontal furcation lesions. In addition, it describes a surgical technique designed to accomplish bone regeneration in class II furcation defects, together with the rationale for the development of this procedure. Results of treatment of 30 defects with this technique are presented in a subsequent report (Gantes et al. 1987).

What's Happening: May 20, 1987, Maine Medical Center

What's Happening

No abstract provided.

What's Happening: May 13, 1987, Maine Medical Center

What's Happening

No abstract provided.

Compositions And Method Of Treatment For Sickle Cell Anemia, Donald F. Diedrich, Christopher L. Maynard

Pharmacology and Nutritional Sciences Faculty Patents

The invention provides a new composition and method for the treatment of sickle cell anemia. . . .

To see the remainder of this abstract, please download this patent.

Update - May 1987, Loma Linda University Center For Christian Bioethics

Update

In this issue:

-- Yoder addresses ethicists at LLU
-- Fletcher and Conolly debate active euthanasia
-- Theological Reflections Regarding AIDS

[ "No Code" Orders: Are They Moral? ]
-- Nurses and 'No Code' Orders
-- Let's Replace "Do Not Resuscitate" With "Care for the Dying"
-- What is a 'No Code' Order?

-- The Pandora's Box of Human Life - Society's Issue: Is Biology or Personality the Essential Ingredient? (Reprint)
-- Cowart, Campbell, Provonsha assess "Ethics at Life's End"

Affect, Cognition And Attention In The Chronic Alcohol Abuser: A Hemispheric Laterality Perspective, Edward P. Kehrwald

Theses and Dissertations

The present study investigated the performance of chronic alcohol abusers and controls on attention, memory, cognition, and emotion from a hemispheric laterality perspective. The purpose of this study was to explore the relationship between these variables and their role in processing of experiences. Measures which are believed to be predominantly a function of the right hemisphere were explored in some depth.

The subjects in the experimental group were chronic alcohol abusers recently admitted to an inpatient addiction facility. The subjects in the control group were volunteers from the community who d1d not have any significant alcohol problem. Only right-handed males …

Histologic Host Response To Polyoxymethylene Prosthesis As A Temporomandibular Joint Condylar Replacement, Frederick R. Mathews

Loma Linda University Electronic Theses, Dissertations & Projects

Polyoxyinethylene (Delrin) is a polyacetyl homopolymer which has been used successfully in many orthopedic joint replacements. To determine histologic host response to Delrin as a temporomandibular joint condylar replacement condyles were removed from ten fully mature macaca fasicularis monkeys. The condyles were replaced with a total prosthetic Delrin condyle attached to a titanium mesh. Specimens obtained at one, two, and six months indicated total acceptance of the Delrin, remodeling of the glenoid fossa and formation of bone between the middle cranial fossa and the roof of the glenoid fossa. These findings would indicate Delrin is a viable option for condylar …

Quantitation Of Teratogenic Effects Of 5-Fluorouracil Administered To Mice In Vivo Or In Submerged Limb Culture, Theresa A. Sanders

Electronic Theses and Dissertations

This study demonstrates the use of submerged limb culture in teratologic testing. Pregnant mice were treated on day 11 of gestation (E11, plug date = E0) with 10, 20 or 40 mg of 5-fluorouracil (FU) per kg body weight. On E17, treated and untreated fetuses were examined for gross malformations and were fixed in 95% ethanol. Reduction of limb size and digital defects, including ectrodactyly (ED), syndactyly (SD), microdactyly and polydactyly were dose-dependent. In parallel studies, pregnant mice were treated on the morning of E11 and embryos were removed either 7h (E11) or 24h (E12) later for submerged limb culture. …

Adaptation Of Striped Bass To Sea Water Following Direct Transfer From Freshwater: Morphological, Biochemical, And Physiological Parameters, Judy A. King

Electronic Theses and Dissertations

There has been heightened interest in the biology of striped bass (Morone saxatilis) because of increased pollution in their native spawning grounds and because of their extensive use in landlocked sport fisheries. Their euryhalinity makes them an excellent species for osmoregulation studies. The objective of this research was to study the rate of adaptation of striped bass gills to sea water (3% salt) after direct transfer from freshwater using biochemical (ion transport enzyme levels), physiological (chloride efflux), and ultrastructural methods. Striped bass have specialized osmoregulatory cells located on the interlamellar and afferent surfaces of their gill filaments as shown by …

Comparative Study Of Elongated Chromosomes In Sheep And Goats And A Proposed Standard, Stephen H. Mensher

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

A cell synchronization technique was used that consistently yielded numerous elongated chromosomes, which are necessary for producing high-resolution G-banding. The prometaphase stage of contraction was determined to have the greatest utility for detailed comparative analysis and, therefore, was used in the preparation of the proposed standard high-resolution karyotypes and idiogram.

A proposed standard high-resolution G-band karyotype of the domestic sheep and goat is presented, along with a high-resolution G-band idiogram of the goat. The karyotypes presented contain considerably more bands than contemporary karyotypes and provide much greater resolution for linear differentiation. The X chromosome of the sheep is acrocentric, rather …

Nutritional Intake And Physical Activity Of An Adult Population With Diabetes Mellitus Using The Continuous Subcutaneous Insulin Infusion Pump, Teresa Jean Matheny

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

This study described three days of dietary intake, physical activity, and glycemic control in 14 female and eight male adult diabetics using Continuous Subcutaneous Insulin Infusion (CSII). Changes in weight after initiation of CSII were also described.

Dietary intakes were analyzed using the NUTREDFO computer program then compared to established standards. Both sexes had mean intakes of zinc, folate, vitamin B₆, and magnesium below the Recommended Dietary Allowances (RDA, 1980) for age and sex. Female consumption of iron and total calories consumed were also below recommendations. When dietary intakes were analyzed on a nutrient per 1,000 kcal basis …

Digest Of The Philadelphia College Of Osteopathic Medicine (Spring 1987), Philadelphia College Of Osteopathic Medicine

Digest

The Spring 1987 issue of the Digest of the Philadelphia College of Osteopathic Medicine includes the following articles:

• Imperatives for Success
• Osteopathic's Surgicenter
• Tage N. Kvist, Ph.D.
• Research at OMCP
• The Changing Challenge of Student Recruitment
• On Campus
• PCOM's Rugby Triumph
• Class Acts
• In Memoriam
• Calendar

An Otopathological Assessment Of Dogs Exposed To Excessive Dietary Fluoride And/Or Suspected Water Borne Toxins, Barbara Ann Hannah

Masters Theses

In 1970, a once very productive Allegan, Michigan dog kennel began experiencing a rash o£ unexplained perinatal deaths and reproductive anomalies in Shetland pups. Anomalies including cleft palate and lip, kinked tails, twisted feet and convulsions immediately before death plagued the neonates. The adult dogs were reported to have tooth mottling, exostoses and auditory and vestibular problems.

Because the dogs had been on high fluoride diets and because the kennel well water was suspected of harboring toxins, a group of 20 Shetland dogs was used to try to find if there was any correlation between the reproductive problems and the …

Noncariogenic Sweeteners: Sugar Substitutes For Caries Control, Curt S. Ayers, Richard A. Abrams

School of Dentistry Faculty Research and Publications

The evidence is clear that the incidence of dental caries is related to the frequency of eating sugar. The use of sugar substitutes is a suggested way of reducing sugar intake. A variety of noncariogenic sweeteners exists, but most have no practical value for caries control because of their technical or safety problems, taste, or cost. Urinary bladder tumorigenic effects have been reported in experimental animals treated with saccharin and cyclamates. Because of concerns for human safety, cyclamates were banned in the U.S., and saccharin use was permitted only by special legislation. The polyalcohols sorbitol and xylitol are important sugar …

1987 Spring No. 13, School Of Medicine Office Of Alumni Affairs

Medicinews

LSU Medicinews Number 13 Spring 1987 was edited by Russell C. Klein, and published by the LSU School of Medicine Office of Alumni and Continuing Education Services.

This issue consists of 24 pages.

Jefferson Alumni Bulletin – Volume Xxxvi, Number 3, Spring 1987

The Bulletin (formerly the Jefferson Medical College Alumni Bulletin)

Jefferson Alumni Bulletin – Volume XXXVI, Number 3, Spring 1987

A call for reform, Page 2

An alumni potpourri, Page 7

Jefferson scene, Page 16

Class notes, Page 24

Maternal And Nutritional Contributions To Infant Rats’Activational Responses To Ingestion, Brian H. Bornstein, Leslie M. Terry, Joseph A. Browde Jr.

Department of Psychology: Faculty Publications

Infant rats deprived of food, maternal care, and the opportunity to suckle display a dramatic behavioral activation and vigorously ingest when provided milk through oral cannulas. These experiments assessed which components of deprivation are important in producing these responses to milk. Nutritional deprivation alone, with or without the presence of an active maternal female, appears to be sufficient to produce ingestion. Behavioral activation, on the other hand, appears to require both nutritional deprivation and deprivation from a maternal female. The effect of maternal stimulation on later behavioral reactivity was not a function of the pups’ opportunity to suckle. However, active …

The Clinicians' Guide To Creutzfeldt-Jakob Disease, Thomas H. Swanson

Henry Ford Hospital Medical Journal

Creutzfeldt-Jakob disease, a transmissible, rapidly progressive dementia of unknown etiology, mimics Alzheimer's disease, presents in middle life, and affects many central nervous system structures. The disease progresses in three distinct stages, culminating in death. Its occurrence is sporadic and its distribution worldwide. Pathological changes are varied, but spongy degeneration of the neuropil is classic. Research on scrapie, the animal model of Creutzfeldt-Jakob disease, has demonstrated that this unconventional, slow disease is transmitted via a small (less than 50,000 mW) particle, which is composed principally of protein. How this infectious particle, variably named prion, virino, or slow virus, invokes disease or …

Aids Update, Evelyn J. Fisher

Henry Ford Hospital Medical Journal

No abstract provided.

Primary Neurologic Complications Of The Acquired Immunodeficiency Syndrome, Stuart N. Kieran

Henry Ford Hospital Medical Journal

No abstract provided.

Back Matter

Henry Ford Hospital Medical Journal

No abstract provided.