Digital Commons Network^™

Dietary And Hormonal Evaluation Of Men At Risk For Prostate Cancer, Donald J. Pusateri

Loma Linda University Electronic Theses, Dissertations & Projects

Relationships between dietary nutrients and plasma and fecal estrone, estradiol-17β, testosterone, and plasma prolactin levels were studied in young Seventh-day Adventist men: 18 nonvegetarians (NV), 20 lacto-ovovegetarians (LOV), and 15 vegans (V). Blood samples and 3 d dietary records were obtained. Contemporaneously collected diet composites and stool samples were analyzed for fiber. The vegetarians consumed significantly more fiber than the omnivores, while NVs and LOVs consumed more saturated fat than the Vs. Although plasma steroid hormone status did not differ, the Vs had significantly higher fecal estrogen levels than the NVs or LOVs. Plasma prolactin levels were significantly higher in …

Short Communication The Use Of Oesophageal - Pharyngeal Samples In The Diagnosis Of Food And Mouth Disease, H.A. Westbury, W.J. Doughty, Pornchai Chamnanpood, Suchinta Tangchaitrong, A.J. Forman

The Thai Journal of Veterinary Medicine

We examined the use of oesphageal-pharyngeal (0/P) samples for the isolation of Foot and Mouth Disease (FMD) virus in animals from which it was difficult to obtain a conventional epithelial tissue specimen. The virus was detected in 42 (28%) of 150 samples, and only 5 (12%) of the 42 cases had positive results when the samples were tested directly with ELISA. The preferred technique for examination of 0/P samples was thus by culturing representative cell samples. The 150 samples came from 22 cases of the disease, with the virus being detected in 16 cases. In 4 of these 16 cases …

Pentylenetetrazol-Induced Seizures In Pigeons And The Effects Of Ethosuximide Thereon, James J. Jakubow

Masters Theses

Previous research has shown that ethosuximide in high enough doses will disrupt operant responding in pigeons. Whether or not these same doses will protect against seizure activity in this species has not been previously tested.

To test this question a system for scoring pentylenetetrazol-induced seizures in pigeons was developed and the effects of ethosuximide on such seizures were evaluated. In Experiment 1 pentylenetetrazol at 15, 27 and 47 mg/kg reliably induced seizures. In Experiment 2 non-behaviorally active and behaviorally active doses of ethosuximide were tested for their seizure controlling effectiveness.

Doses of 20, 40, 80, 160 and 320 mg/kg ethosuximide …

What's Happening: November 16, 1988, Maine Medical Center

What's Happening

No abstract provided.

Current Literature, Catholic Physicians' Guild

The Linacre Quarterly

Material appearing below is thought to be of particular interest to Linacre Quarterly readers because of its moral, religious, or philosophic content. The medical literature constitutes the primary but not the sole source of such material. In general, abstracts' are intended to reflect the substance of the original article. Contributions and comments from readers are invited. (E. C. Laforet, M.D. , 2000 Washington St., Newton Lower Falls, MA. 02162.)

Physical Linkage Of The Genes For Platelet Membrane Glycoproteins Iib And Iiia., Paul F. Bray, Greg Barsh, Jean-Philippe Rosa, Xue Ya Luo, Ellen Magenis, Marc A. Shuman

Cardeza Foundation for Hematologic Research

The fibrinogen receptor on human platelets is a prototypic member of the integrin family and is composed of subunit glycoproteins IIb (gpIIb) and IIIa (gpIIIa) in a 1:1 stoichiometric ratio. We have isolated cDNA clones for gpIIb and gpIIIa and localized both genes to chromosome 17. In the current study, several approaches were used to localize and map the genes for gpIIb and gpIIIa. A preliminary evaluation of subchromosomal localization was performed by using a panel of mouse-human somatic cell hybrids that contain different amounts of the long arm of human chromosome 17. Southern hybridization to the DNA of these …

Biomedical Ethics In The Soviet Union, Richard T. De George

Center for the Study of Ethics in Society Papers

*This is an abbreviated version of a paper presented first at a joint MIT-Harvard Faculty Seminar on the humanistic dimensions of Soviet Science on November 20, 1987, and then at the Western Michigan University Ethics Center on February 10, 1988. An expanded, fully documented version, under the title "Soviet Biomedical Ethics" will appear in a volume edited by Loren Graham, and tentatively entitled The Human Side of Soviet Science, Harvard University Press, 1989.

Population Amalgamation And Genetic Variation: Observations On Artificially Agglomerated Tribal Populations Of Central And South America, R Chakraborty, P E Smouse, J V Neel

Faculty, Staff and Student Publications

The interpretation of data on genetic variation with regard to the relative roles of different evolutionary factors that produce and maintain genetic variation depends critically on our assumptions concerning effective population size and the level of migration between neighboring populations. In humans, recent population growth and movements of specific ethnic groups across wide geographic areas mean that any theory based on assumptions of constant population size and absence of substructure is generally untenable. We examine the effects of population subdivision on the pattern of protein genetic variation in a total sample drawn from an artificial agglomerate of 12 tribal populations …

What's Happening: October 19, 1988, Maine Medical Center

What's Happening

No abstract provided.

Nurses Alumni Association Bulletin, Fall 1988, Alice C. Boehret, Thelma Showers Morris, Vivian I. Moyer, Frances Baker-Anderson-Crossan, Judith A. Robins, Nancy Powell, Betty Piersol, Mabel C. Prevost, Carole Rosle, Nancy Scott, Doris E. Bowman, Margaret Summers, Katherin Flickinger Aagaard

Nursing Alumni Bulletins

Alumni Meeting Calendar

Officers and Committee Chairmen

The President's Message

The Jefferson Hospital School Of Nursing Roll Of Honor

Treasurer's Report

Glimpses From An Earlier Time

Accentuate The Positive

"I Have Noticed"

Reaching A Cherished Goal

Special Achievement Award

Archives And The Nursing Experience

Happy Birthday

Fiftieth Anniversary

CAHS Alumni Directory.

Resume Of Minutes Of Alumni Association Meetings

Alumni Office News

Committee Reports

Relief Fund

Satellite

Scholarship

Social

Bulletin

Finance

Do Something

Volunteers Needed

Bequests

Have We Changed?

The Original Coal Miners Daughter Remembers

Congratulations From The Alumni Association

Luncheon Photos

The Butterfly And The Caterpillar

Forty Three Attend Fortieth …

Full Issue, Vol. 12

Great Basin Naturalist Memoirs

No abstract provided.

Santa Clara Magazine, Volume 31 Number 1, Fall 1988, Santa Clara University

Santa Clara Magazine

12 - MY CHINA YEAR Cathy Morrissey '85 guides us through her year in China, teaching English as a second language in Handan.

19 - IT PAYS TO LET YOUR KID RUN WILD The story of a remarkable relationship between a Japanese firm and Michael Franz '75.

21 - THE REWAK YEARS Alumna-journalist Jeanne Huber describes the way Santa Clara grew during the Rewak administration.

26 - THE DEGNAN WAY How a respected English professor turns undergraduates into professional writers.

End Matter, Vol. 12

Great Basin Naturalist Memoirs

No abstract provided.

The Synthesis And Evaluation Of 5-Phenyloxazolidines As Potential Cardiovascular Drugs, Tammy C. Wang

Chemistry & Biochemistry Theses & Dissertations

Drugs such as adrenoceptor antagonists and certain centrally acting agents are known to lower blood pressure and thus serve as clinically useful antihypertensive agents. Norepinephrine 4, a natural ∝-adrenoceptor agonist, is the major agent associated with increased blood pressure in the periphery. Based on a careful structure-activity comparison, a series of substituted oxazolidines, 20, 21, 22 and 23, have been designed as possible antihypertensive candidates. Specifically, 22 and 23 have been synthesized to serve as potential norepinephrine antagonists.

Preliminary evaluation of these compounds indicated that they were not antihypertensive in nature. The more active compound, 23, …

End Matter, Vol. 12, Index

Great Basin Naturalist Memoirs

No abstract provided.

Front Matter, Vol. 12

Great Basin Naturalist Memoirs

No abstract provided.

Newer Therapies In Hypercalcemia And Metabolic Bone Disease, Hunter Heath Iii

Henry Ford Hospital Medical Journal

No abstract provided.

The Inhibition Of Bone Formation Occurring Under Weightlessness : The Effect Of Skeletal Unloading On Serum Levels Of A Bone-Derived Growth Factor, Jean D. Sibonga

Loma Linda University Electronic Theses, Dissertations & Projects

A deleterious effect of spaceflight on human health is the loss of bone associated with the prolonged lack of gravitational stress on the skeleton. A potential for bone loss is indicated by the hypercalciuria and decreased heel bone density determined in Skylab astronauts. Histological studies of juvenile laboratory rats in actual spaceflight and in simulation models document a suppression of bone formation with little alteration of bone resorption. The mechanism for net bone loss needs to be defined in order to develop measures for its prevention or correction.

Skeletal growth factors, which may mediate coupling and locally regulate bone volume …

Age-Related Changes In Meissner Corpuscles Of Diabetic Mice As Observed By Electron Microscopy, Vicky R. Ras

Loma Linda University Electronic Theses, Dissertations & Projects

Light touch and low-frequency vibration sense are often impaired in diabetic patients. Meissner corpuscles are distally located mechanoreceptors that respond to these stimuli. Peripheral sensory neuropathy in diabetes progresses from distal to proximal, therefore, Meissner corpuscles are ideally suited to study diabetic neuropathy in the C57BL/Ks (db/db) mouse.

Corpuscles from the forepaw digital pads of 9 diabetic and 9 nondiabetic littermates were studied by electron microscopy. These were divided into 3 age groups; 2.5 months, 10 months, and 17 months old.

Ultrastructural changes observed within various receptor components were myelin figures, multivesicular bodies, vacuoles, basal lamina duplication, abnormal and enlarged …

Campylobacter Jejuni/Coli In Diarrhoeic And Healthy Animals, Suvanee Supave, Viroj Kitikoon, Thaiyooth Chintana, Indhira Kramomtong

The Thai Journal of Veterinary Medicine

Faecal materials from 132 diarrhoeic and 19 healthy household dogs were cultured for Campylobacter jejuni/coli and other enteric organisms. Twenty-four (18.2% C. jejuni/coli were isolated from diarrhoeic dogs and 3 15.8% from healthy dogs. Non-cholera Vibrio 14.6% and Salmonella spp. (1.5%) were also detected from diarrhoeic dogs but none from the healthy group. Shigella and V. cholerae-01 were not recovered from the two groups of animal. Three chickens and six swines with history of diarrhoea were also cultured for C. jejuni/coli but the number of the two animals studies was too small to draw any conclusion.

Serological Montitoring Of Cattle Immunised With Foot-And-Mouth Disease Virus Tppe O Vaccine, H.A. Westbury, Pornchai Chamnanpood

The Thai Journal of Veterinary Medicine

Thirteen groups of cattle in five provinces of Thailand were tested serologically for their response to Foot-and-mouth disease virus type ◊ vaccine. The animals were tested before and after immunisation by the ELISA procedure. The proportion of animal with significant titers of antibody before immunisation was 64 percent (range 19 - 95 percent}, while proportion with antibody after immunisation was 86 percent (range 42 - 100 percent). Prevaccination antibody had an effect on the response of the animal to immunisation, while some cattle apparently fully susceptible animals failed to respond to the vaccine. Further study on ways to overcome the …

A [6-14c] Glucose Autoradiographic Study Of The Rat Brainstem Under Hypercapnic And Hypocapnic Conditions: Identification Of Respiratory-Related Regions, Tobey M. Leung

Loma Linda University Electronic Theses, Dissertations & Projects

The effects of systemic hypercapnia on brainstem metabolism were studied with the [6-¹⁴C] glucose autoradiography method. Neuronal pools which are metabolically active take up more [6-¹⁴C] glucose and maybe revealed pictorially as darker areas on autoradiograms. Since a high concentration of carbon dioxide stimulates central chemoreceptors and hence enhances respiratory drive, the darker regions on the autoradiograms may represent regions concentrated with respiratory-related neurons. Two discrete regions in the ventrolateral medulla (a column near nucleus ambiguus and a column in the lateral reticular nucleus) appeared dark and were analyzed with an image processing system, which converted …

Computer Analysis Of Cross Sections Of Leaves Of Chrysothamnus Taxa And Their Relation To Environmental Conditions, J. Huang, W. M. Hess, D. J. Weber, E. D. Mcarthur, S. E. Meyer, R. Seegmiller

Great Basin Naturalist

Thirty-eight accessions of 20 taxa (species and subspecies) of Chrysothamnus from a range of environments were grown in a uniform garden. During mid-June, terminal and lateral leaves were removed, fixed, and processed for light-microscopy studies. Area and perimeter measurements of ink tracings of midleaf vein cross sections were measured using computer-scan techniques. Leaf area and perimeter were compared with vein perimeter and area measurements. Area and perimeter of these Chrysothamnus leaves varied in response to the environment at the collection location. Plants native to hot, dry conditions had small, thick leaves, whereas plants native to cooler, more mesic conditions had …

Phloretin And Phlorizin Derivative Containing Compounds, Donald F. Diedrich, Susanne L. Diedrich

Pharmacology and Nutritional Sciences Faculty Patents

Compounds including phloretin and/or phlorizin derivatives coupled to an undigestible and non-absorbable matrix are provided. The compounds have pharmacological efficacies. They inhibit sugar uptake from the intestine and may be used in composition form in methods for treating diabetes and for promoting weight loss. A method for the manufacture of these compounds and a novel intermediate phlorizin derivative for making these compounds are also disclosed.

K+ Efflux In Nih Mouse 3t3 Cells And Transformed Derivatives: Dependence On Extracellular Ca2+ And Phorbol Esters., Martin Lubin

Dartmouth Scholarship

In culture medium deficient in Ca2+, NIH mouse 3T3 cells lose K+, gain Na+, and stop growing. A marked increase in the rate of K+ efflux accounts for this loss; Na+, K+-ATPase pump activity increases but does not fully compensate for enhanced K+ efflux. Phorbol esters and cycloheximide inhibit K+ loss in Ca2+-deficient medium. Phorbol esters inhibit K+ efflux from human fibroblasts as well, even at physiological levels of Ca2+. Two cell lines derived from NIH-3T3, one transformed by a simian virus 40 deletion mutant, the other by the polyoma virus oncogene encoding the middle-sized tumor antigen, retain K+ and …

Osteoporosis As A Community Health Problem: Lessons Learned From Studying Hypertension, Michael Kleerekoper, Dorothy A. Nelson

Henry Ford Hospital Medical Journal

Campaigns to increase the medical and lay communities' awareness and understanding of the problems of unrecognized and untreated hypertension have led to a progressive decline in morbidity and mortality from hypertension-related diseases. While osteoporosis is also a community health problem, educational and awareness campaigns are still in their infancy and decades may pass before these result in a declining morbidity and mortality from osteoporosis. We identify areas where concepts learned from years of hypertension research might be applicable lo the study of osteoporosis as a community health problem and thereby lessen the time needed to effect a declining morbidity and …

Biophysical Methods For Estimating In Vivo Body Composition: The Determination Of The Adipose Compartment, Luther E. Preuss, Frank P. Bolin

Henry Ford Hospital Medical Journal

The status of the human body's major components (adipose mass, lean mass, body water, etc) and their change with time are of clinical importance. Deviation of these body components from a stable condition may be imposed by nutrition or disease, and a return to the normal body state may be brought about by appropriate medical care. Thus accurate quantitation of these components is an important goal. This field of study can be traced to the early 1800s, with a major thrust starting in the 1940s and continuing lo the present. The last four decades have shown an accelerated development of …

Occurrence Of Alzheimer Disease In Michigan: An Epidemiologic Review Of Rates And Risk Factors, Christine Cole Johnson

Henry Ford Hospital Medical Journal

Alzheimer disease is a progressive degenerative neurological disorder of insidious onset characterized by the deterioration of cognitive functioning. Little is known about the etiology and epidemiology of this condition. The only risk factor consistently associated with Alzheimer disease is advancing age. As the population of the elderly continues to grow, many public agencies, including those in Michigan, are concerned about social, personal, and financial implications and seek estimates of the number of people with dementia. To date, mortality rates based on vital statistics have been noninformative because Alzheimer disease is difficult lo diagnose clinically and has been considered to be …

The Effects Of Spouse-Based Cognitive-Behavior Therapy On The Treatment Of Agoraphobia, Joan Woods

Dissertations

The purpose of this clinical research was to determine whether spouse-supported treatment of agoraphobia would result in greater improvement on measures of exposure and avoidance than would individual treatment or no treatment. It was hypothesized that Couples Treatment subjects would demonstrate a significantly greater change from pretest to posttest than would Individual Treatment subjects or No-Treatment Control subjects. The study further predicted that significant improvements would be demonstrated for both treated groups on the same outcome measures, pretest to posttest and from pretest to follow-up.

Total N was 10 subjects, all were agoraphobic, married, and female, with 4 in Couples …

Commencement Program 1988, Loma Linda University

Commencement Programs

CONTENTS

2 | 1988 Events of Commencement

3 | Academic Procession

4 | The Speakers

8 | The Honorees

12 | The Zapara Awards

Order of Programs

• School of Medicine, 14
• School of Dentistry, 20
• Graduate School, 26
• School of Nursing, 31
• School of Public Health, 35
• College of Arts and Sciences, School of Business and Management, and School of Education, 41
• School of Allied Health Professions, 52