Digital Commons Network^™

Umbilical Cord Separation Time In Infants, Helen Bailey

Theses : Honours

Umbilical cord separation vary throughout the world. This variation makes it difficult to advise parents when the umbilical cord will separate. The purpose of this study was to determine the length of time until umbilical cord separation for a sample of babies born in Perth. A descriptive study was conducted at two hospitals using two different cord care methods. Data were collected on a convenience sample of 228 babies by a structures telephone interview. Mothers were contacted at home after cord separation and asked questions about the study variables. Influencing variables included type and frequency of cord care, sex, mode …

The Role Of Small Peptides In Cancer Physiology And Chemotherapy, Bao-Ling Tsay

Theses and Dissertations in Biomedical Sciences

The targeting of proven anticancer drugs specifically to cancer cells would provide a unique opportunity to restrict neoplasms without damaging the cancer patient. The present research utilizes the phenomenon of illicit transport, i.e. the coupling of normally impermeant metabolites to permeant metabolites, in targeting the drug melphalan to mouse Ehrlich ascites tumor cells. The dipeptide beta-alanyl-melphalan was synthesized and tested in vitro for toxicity towards mouse Ehrlich ascites tumor cells, mouse liver cells, and mouse 3T3 embryonic cells. The parent compound, melphalan, was used as a control treatment. In addition, both melphalan and beta-alanyl-melphalan were utilized in in vivo chemotherapeutic …

Obesity: A Biobehavioral Point Of View, M. Katahn, Mark R. Mcminn

Faculty Publications - Doctor of Psychology (PsyD) Program

Excerpt: "If you ask an overweight person, “Why are you fat?’, you will, almost invariably, get the answer, “Because 1 eat too much.” You will get this answer in spite of the fact that of thirteen studies, six find no significant differences in the caloric intake of obese versus nonobese subjects, five report that the obese eat significantly less than the nonobese, and only two report that they eat significantly more."

Cancer In Louisiana: 1988, Volume 5, Louisiana Tumor Registry, Joel L. Nitzkin, Frank D. Groves, Jean Fike Craig, Pelayo Correa, Vivien W. Chen, Elizabeth T.H. Fontham, Diego E. Zavala

Policy & Position Papers

Mission To collect and report complete, high-quality, and timely population-based cancer data in Louisiana to support cancer research, control, and prevention. Vision To reduce suffering and death from cancer using information collected by the Louisiana Tumor Registry. History Cancer registration in Louisiana began in 1947 at the Charity Hospital Tumor Registry in New Orleans. In 1974, as part of its Surveillance, Epidemiology and End Results (SEER) Program, the National Cancer Institute provided funds for a population-based cancer incidence and survival registry covering Jefferson, Orleans, and St. Bernard parishes. Five years later, the Louisiana Tumor Registry (LTR) was transferred to the …

Continuous Passive Motion After Knee Arthroscopy, Lisa Bauman

Masters Theses

The purpose of the study was to investigate the effect of continuous passive motion (CPM) after arthroscopy. A CPM machine was used one hour following knee surgery. Statistical analysis was performed to determine differences in knee range of motion (ROM), strength and circumference, at time intervals preoperatively, one, seven, and twenty-eight days following surgery. The analysis of variance revealed no significant difference between the CPM and control groups for any parameter. A significant interaction effect between treatment and time was demonstrated one day after surgery for extension, joint line circumference, and midthigh circumference; and 28 days after surgery for the …

Update - December 1989, Loma Linda University Center For Christian Bioethics

Update

In this issue:

-- Australia's Herbert Clifford will lecture at Loma Linda on February 24
-- Claremont Conference endorses "The Right to Choose Death"
-- Michael and Helen Pearson arrive from England
-- Contributors receive monthly audio cassettes

[ Nancy Cruzan and the Courts ]
-- The Persistent Vegetative State
-- Nancy Cruzan is Already Dead
-- Nancy Cruzan is Not a Vegetable
-- My Family's Anguish

-- The Right to Choose Death

An Investigation Of Pitch Perturbation And Vocal Intensity Characteristics Of Stutterers And Nonstutterers, Carmen M. Bamberg

Masters Theses

Pitch and amplitude perturbation values were compared for nine adult stutterers and nine adult nonstutterers. Each subject produced ten sustained phonations of the vowels /a/ and /i/. An automatic pitch-synchronous autocorrelation fundamental frequency tracker was used to extract period and amplitude measures.

Findings revealed that: (a) stutterers had significantly more vocal shimmer than nonstutterers (p = .01), (b) F-ratios for percent jitter between groups approached (p = .07) but did not reach significance, and (c) the vowel /a/ was produced with higher levels of jitter and shimmer than the vowel /i/. Results support the notion that instability of the …

The Use Of Flumequine For Treatment Of Bacterial Infection In Babanana Tiger Prawn (Penaeus Monodon) And Seabass (Lates Calcarifer), Jirasak Tangtrongpiros, Weena Koeypudsa

The Thai Journal of Veterinary Medicine

The efficacy of flumequine was studied both in vitro and in vivo. The MIC was 0.5 ug/ml to 17 strains of A. hydrophila and 23 strains of V. anguillarum isolated from affected fishes and shrimps in Thailand. Sodium chloride (Nacl) has no effect on flumequine in inhibiting the growth of these bacterias. The mortality of shrimp (P. monodon) and seabass (L. calcarifer) was reduced at the dosage of 5 ppm, 10 ppm and 20 ppm when flumequine was administered every day or every 2 day. This drug should be one of the drug of choice in treatment of bacterial infection …

Health Effects Of Air Pollutants (Sulfur Dioxide, Ozone, And Carbon Monoxide), Robert A. Bethel

Air Quality Protection in the West (November 27-28)

19 pages (includes illustrations).

Contains references.

What's Happening: November 22, 1989, Maine Medical Center

What's Happening

No abstract provided.

Significance Of Premature Stop Codons In Env Of Simian Immunodeficiency Virus, Toshiaki Kodama, Dawn P. Wooley, Yathirajulu M. Naidu, Harry W. Kestler Iii, Muthiah D. Daniel, Yen Li, Ronald C. Desrosiers

Neuroscience, Cell Biology & Physiology Faculty Publications

The location of the translational termination codon for the transmembrane protein (TMP) varies in three infectious molecular clones of simian immunodeficiency virus from macaques (SIV_mac). The SIV_mac251 and SIV_mac142 infectious clones have premature stop signals that differ in location by one codon; transfection of these DNAs into human HUT-78 cells yielded virus with a truncated TMP (28 to 30 kilodaltons [kDa]). The SIV_mac239 infectious clone does not have a premature stop codon in its TMP-coding region. Transfection of HUT-78 cells with this clone initially yielded virus with a full-length TMP (41 kDa). …

Humanae Vitae, Natural Law, And Catholic Moral Thought, William E. May

The Linacre Quarterly

No abstract provided.

Update - November 1989, Loma Linda University Center For Christian Bioethics

Update

In this issue:

-- Character, Virtue, and Self-Interest in the Ethics of the Professions (Excerpts from the Second Annual Jack W. Provonsha Lecture)
-- Minnesota Bioethics Retreat and Conference

Occupational Therapy In Early Intervention: A Family-Centered Approach., Roseann C. Schaaf, L L. Mulrooney

Department of Occupational Therapy Faculty Papers

This article describes a framework for occupational therapy service provision in early intervention settings and presents pilot data aimed at examining the framework's effectiveness. The Family-Centered Framework for Early Intervention is a synthesis of concepts from the Model of Human Occupation (Kielhofner & Burke, 1980) and from the literature on play. It encompasses a systematic, holistic approach that considers the child and the family within the context of their life environments. In this framework, play is used both as an evaluative tool and as an intervention modality that addresses the volition, habituation, and performance of the child and family as …

Qualitative Metabolism Assessment Using High Performance Thin Layer Chromatography, Shih-Ling Chang

Veterinary Science Faculty Patents

A method for the qualitative assessment of oxidative drug metabolism deficiencies, preferably for the qualitative assessment of dextromethorphan metabolism, in a subject comprises analyzing a sample fluid from the subject, for example urine, which contains metabolites of a probe drug using high performance thin layer chromatography.

Radio Transmitter Attachment For Chukars, Bartel T. Slaugh, Jerran T. Flinders, Jay A. Roberson, M. Ray Olson, N. Paul Johnston

Great Basin Naturalist

Thirty-seven Chukars (Alectoris chukar), fitted with conventional poncho-type radio transmitters, were released on Antelope Island in Utah's Great Salt Lake. Twenty-seven removed their radios, averaging three days after release. The remaining 10 died from predation (average 15 days). Twenty-two Chukars with pleated and six with harness ponchos were then released. Five of the pleated ponchos were removed (average four days), and 17 resulted in mortality (average two days). All six harness poncho-equipped birds were dead the following day. A consequential laboratory study comparing various attachment methods (conventional, pleated, harness, and "irreversible" flange poncho vs. bellystrap and wingstrap backpack) …

Ua12/2/1 College Heights Herald, Vol. 65, No. 19, Wku Student Affairs

WKU Administration Documents

WKU campus newspaper reporting campus, athletic and Bowling Green, Kentucky news. This issue contains articles:

• Hernes, Thomas. Officials Seek Gift for Recreation Center – Preston Health & Activities Center
• Lawson, Jamie. Graduate Ron Jerrell Tells 400 His Story of AIDS
• Summers, Kaye & Allison Tutt. Hilltopper Athletic Foundation Raises Support, $660,000
• Summers, Kaye & Allison Tutt. Students, School Lend Services to Athletics
• Eugene Evans to Outline Goals at Open Forum
• Potter Lot Closed Until Tomorrow
• University Logo to be Unveiled Today
• Kinslow, Gina. Central Women Get Tucked In – Minton Hall, Barnes-Campbell Hall
• Green, Travis. Associated Student Government Wants AIDS …

Anencephalic Newborns As Organ Donors: An Assessment Of "Death" And Legislative Policy, Kathleen L. Paliokas

William & Mary Law Review

No abstract provided.

Embryonic Chicken Fibroblast Collagen Binding Proteins: Distribution, Role In Substratum Adhesion, And Relationship To Integrins, Roy C. Ogle, A. Jeannette Potts, Marchall Yacoe, Charles D. Little

School of Medical Diagnostics & Translational Sciences Publications

Collagen binding proteins (CBP) are hydrophobic, cell surface polypeptides, isolated by collagen affinity chromatography. Antibodies to CBPs inhibit the attachment of embryonic chicken heart fibroblasts to native type I collagen fibrils in a dose-dependent manner. The CBP antibodies also induce rounding and detachment of cells adherent to a planar substratum. This process of antibody-mediated substratum detachment resulted in a clustering of CBP and cell-associated extracellular matrix at the cell surface, and the rearrangement of filamentous actin. Other functional studies showed that cells grown within a three-dimensional gel of type I collagen cannot be immunostained at the cell surface with CBP …

The Chironian Vol. 106, New York Medical College

The Chironian

No abstract provided.

Regulation Of Queuine Insertion Into Transfer Rna: Effects Of Tumor Promoters, Bonnie Jean Brooks

Chemistry & Biochemistry Theses & Dissertations

The purpose of this study was to treat normal human fibroblasts with known tumor promoters and observe queuine modification of tRNA. The queuine insertion enzyme, tRNAguanine ribosyltransferase, was studied in vivo and in vitro. Tumor promoter-treated human fibroblast cultures exhibited variable queuine-insertion rates with a transient inhibition that correlated with variable levels of queuine modified tRNA over time in culture from passages 3 — 8. In contrast the in vitro studies showed that phorbol cetera and saccharin actually increased insertion with strong evidence indicating phosphorylation as a positive modulating force of the enzyme activity. It is proposed that chronic stimulation …

The Determination Of Tamoxifen Citrate In Human Blood Serum And Semen, Karimdad Tahmoresi

Chemistry & Biochemistry Theses & Dissertations

High performance liquid chromatography (HPLC)methodologies for the determination of tamoxifen and its metabolites 4-hydroxytamoxifen and n-desmethyltamoxifen, and using cis-tamoxifen as an internal standard have been developed.

Clinical analyses of tamoxifen and its metabolites in human serum and semen, were performed as follows: The analytes were extracted from serum and semen with hexane, the hexane evaporated, the dried extract then reconstituted with methanol, followed by reverse phase high performance liquid chromatography.

Between-run coefficients of variation (CV'S) for tamoxifen and n-desmethyltamoxifen for serum sample analyses, (n = 15) were, 4% and 13% at mean (SD) concentration of 140.2 (6.2) and 71.8 (9.8) …

What's Happening: September 13, 1989, Maine Medical Center

What's Happening

No abstract provided.

Adrenal Cortex Transplantation After Bilateral Total Adrenalectomy In The Rat, Georg F. W. Scheumann, Wolfgang F. A. Hiller, Soren Schroeder, T. Schurmeyer, Jurgen Klempnauer, Henning Dralle

Henry Ford Hospital Medical Journal

An experimental animal model with adrenal cortex transplantation was developed to study adrenal cortex replacement therapy in patients with multiple endocrine neoplasia type 2 who have had bilateral adrenalectomy for pheochromocytomas. Adrenal cortex of syngenetic rats was isolated from the medulla by collagenase digestion and a defined sedimentation. The cell suspension of the cortical cells was implanted under the kidney capsule of untreated syngenetic rats. After two weeks the recipients were bilaterally adrenalectomized. Serum corticosterone levels were measured as an estimate of function of the grafts. All recipients were healthy throughout the observation period, whereas all adrenalectomized controls died within …

A Novel Parathyroid Hormone-Related Gene Product, T. J. Martin, J. A. Danks

Henry Ford Hospital Medical Journal

A parathyroid hormone-related protein (PTHrP) has been invoked as being responsible for the humoral hypercalcemia of malignancy. Eight of the first 13 amino acids of PTHrP are identical with those in PTH, but there is no other significant homology. The PTHrP gene is located on chromosome 12, whereas that for PTH is on chromosome 11, and the two genes are probably related by a duplication process. Antisera against PTHrP(1-34), which cross-read poorly or not at all with PTH, and antisera against other parts of PTHrP not homologous to PTH were used in immunocytochemistry, using a peroxidase-antiperoxidase method, to identify PTHrP …

Evolutionary Pathways Of The Calcitonin (Calc) Genes, Cornelis J. M. Lips, Rolf A. Geerdink, Maria G. Nieuwenhuis, Jaap Van Der Sluys Veer

Henry Ford Hospital Medical Journal

Recombinant DNA techniques have made it possible to establish the structure of various genes encoding polypeptide hormones. Comparison of nucleotide sequences of the calcitonin (CALC) genes in man has revealed surprising similarities and variations. These findings and the homologies among the sequences in different species offered an opportunity for speculation about relationships between these genes and about their evolutionary origin. The first gene (CALC-I) directing the synthesis of calcitonin (CT) or CT gene-related peptide (CGRP) comprises six exons and gives rise to two mRNAs by an alternative RNA-processing mechanism. The homology between CGRP and CT reflects their common origin. The …

Localization Of Metastases From Medullary Thyroid Carcinoma Using Different Methods, Rosa C. Cabezas, Luis Berna, Montserrat Estorch, Ignacio Carrio, Angeles Garcia-Ameijeiras

Henry Ford Hospital Medical Journal

We analyzed the efficiency of three different noninvasive methods in the localization of recurrent medullary thyroid carcinoma (MTC). Nine patients (six females and three males) with biochemical evidence of disease after primary surgery were subjected to anti-carcinoembryonic antigen (anti-CEA) antibody, meta-iodo-benzylguanidine (MIBG), and computed tomography. Another female patient, in biochemical remission for six years after initial surgery, was also studied using the same methods. Three of the ten patients had negative results with all three methods (including the patient in remission). The other seven patients showed abnormal uptake of labeled anti-CEA antibody in various localizations: only two of these patients …

Vital Signs, September 1989, Boonshoft School Of Medicine

Vital Signs

A twelve page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, alumni profiles, class notes, and more.

Bulletin 4133 - Fungal Diseases Of Pasture Legumes In Western Australia, M. J. Barbetti

Bulletins 4000 -

Subterranean clover (Trifolium subterraneum L.) is the most important annual pasture legume in Western Australia, forming the basis of some 6.5 million ha of annual pastures. The success of subterranean clover may be attributed to its ability to increase soil fertility as a consequence of nitrogen fixed, to withstand heavy grazing, to control soil erosion and, with some cultivars, to tolerate waterlogging. Fungal diseases have been a major limitation to the productivity of subterranean clover, affecting both the amount of plant matter and the quantity of seed produced.

Annual medic (Medicago spp., in particular M. polymorpha L.) is also an …

What's Happening: August 30, 1989, Maine Medical Center

What's Happening

No abstract provided.