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Articles 1 - 30 of 187
Full-Text Articles in Entire DC Network
Digging Deeper: Quality Of Patient-Provider Communication Across Hispanic Subgroups, Lorraine S. Wallace, Jennifer E. Devoe, Edwin S. Rogers, Joanne Protheroe, Gillian Rowlands, George E. Fryer
Digging Deeper: Quality Of Patient-Provider Communication Across Hispanic Subgroups, Lorraine S. Wallace, Jennifer E. Devoe, Edwin S. Rogers, Joanne Protheroe, Gillian Rowlands, George E. Fryer
Faculty Publications and Other Works -- UT Graduate School of Medicine
Background
Recent research suggests that ethnic subgroup designation plays an important role in health-related disparities among Hispanics. Our objective was to examine the influence of Hispanics' self-reported ethnic subgroup designation on perceptions of their health care providers' communication behaviors.
Methods
Cross-sectional analysis of the 2005 Medical Expenditure Panel Survey (MEPS). Participants included non-institutionalized Hispanics (n = 5197; US population estimate = 27,070,906), aged ≥18 years, reporting visiting a health care provider within the past 12 months. Six (n = 6) items were used to capture respondents' perceptions of their health care providers' communication behaviors.
Results
After controlling for socio-demographic covariates, …
Ada News - 12/14/2009, American Dental Association, Publishing Division
Ada News - 12/14/2009, American Dental Association, Publishing Division
ADA News
Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.
No Free Lunch? Current Challenges Facing The National School Lunch And School Breakfast Programs, Eileen Salinsky
No Free Lunch? Current Challenges Facing The National School Lunch And School Breakfast Programs, Eileen Salinsky
National Health Policy Forum
This background paper describes important characteristics of the National School Lunch Program and the School Breakfast Program, reviews U.S. Department of Agriculture rules regarding the nutritional content of school meals, and examines compliance with current nutrition standards. It also considers the dietary status and obesity risk of meal program participants, discusses proposed improvements to nutritional standards and meal requirements, and highlights key legislative issues.
Collagenous Myofibroblastic Tumor Of The Mandible: Case Report Of A Unique Locally Aggressive Neoplasm Journal Head And Neck Pathology, Jason W. Nash, Amy C. Hessel, Nadarajah Vigneswaran, Adel K. El-Naggar
Collagenous Myofibroblastic Tumor Of The Mandible: Case Report Of A Unique Locally Aggressive Neoplasm Journal Head And Neck Pathology, Jason W. Nash, Amy C. Hessel, Nadarajah Vigneswaran, Adel K. El-Naggar
Journal Articles
We report a locally aggressive collagenous myofibroblastic neoplasm of the mandible in an 18-year-old male. Clinically, the lesion presented with rapid growth and irregular mandibular bone destruction. Grossly, the tumor was 10 cm in greatest dimension, light-tan, firm, and involving the posterior one-thirds of the body and inferior half of the left mandibular ramus. Histologically, the lesion was composed of a loose spindle cell proliferation interspersed with periodic dense bands of collagen. The spindle cells reacted positively to smooth muscle actin, calponin, and focally to desmin and were negative for S-100, pan-cytokeratin, CD99, CD34 and caldesmon, supporting myofibroblastic derivation. At …
Priming Deficiency In Male Subjects At Risk For Alcoholism: The N4 During A Lexical Decision Task, Lance O. Bauer
Priming Deficiency In Male Subjects At Risk For Alcoholism: The N4 During A Lexical Decision Task, Lance O. Bauer
UCHC Articles - Research
Abstract
Background
While there is extensive literature on the relationship between the P3 component of event-related potentials (ERPs) and risk for alcoholism, there are few published studies regarding other potentially important ERP components. One important candidate is the N4(00) component in the context of semantic processing, as abnormalities in this component have been reported for adult alcoholics.
Method
A semantic priming task was administered to non-alcohol dependent male offspring (18 to 25 years) of alcoholic fathers [high risk (HR) n=23] and non-alcoholic fathers [low risk (LR) n=28], to study whether the two groups differ in terms of the N4 component. …
Pulp Polyp Associated With A Natal Tooth: Case Report, Brian D. Hodgson, Rodney Vergotine, Lance Lambert
Pulp Polyp Associated With A Natal Tooth: Case Report, Brian D. Hodgson, Rodney Vergotine, Lance Lambert
School of Dentistry Faculty Research and Publications
Natal teeth are an infrequent occurrence at birth. Often these teeth are extracted because they are very mobile and pose a risk of aspiration. This is a rare case in which a natal tooth was extracted by the pediatrician with his fingers. A root fragment remained and out of this developed a large pulp polyp. This relationship has not been previously reported.
Dental Treatment Under General Anesthesia In Healthy And Medically Compromised/Developmentally Disabled Children: A Comparative Study, Juan Pablo Loyola-Rodriguez, Veronica Zavala-Alonso, Cinthya L. Gonzalez-Alvarez, Lilia A. Juarez-Lopez, Nuria Patiño-Marin, Cesar D. Gonzalez
Dental Treatment Under General Anesthesia In Healthy And Medically Compromised/Developmentally Disabled Children: A Comparative Study, Juan Pablo Loyola-Rodriguez, Veronica Zavala-Alonso, Cinthya L. Gonzalez-Alvarez, Lilia A. Juarez-Lopez, Nuria Patiño-Marin, Cesar D. Gonzalez
School of Dentistry Faculty Research and Publications
Aim: To compare the type, number of procedures and working time of dental treatment provided under dental general anesthesia (DGA) in healthy and medically compromised/developmentally disabled children (MCDD children). Design: This cross-sectional prospective study involved 80 children divided into two groups of 40 children each. Group 1 consisted of healthy and Group 2 consisted of MCDD children. Results: Healthy children needed more working time than MCDD children, the means being 161±7.9 and 84±5.7 minutes, respectively (P= 0.0001). Operative dentistry and endodontic treatments showed a significant statistical difference (P= 0.0001). The means of procedures were 17±5.0 for healthy children and 11±4.8 …
The Vaginal Microflora In Relation To Gingivitis, Rutger Persson, Jane Hitti, Rita Verhelst, Mario Vaneechoutte, Rigmor Persson, Regula Hirschi, Marianne Weibel, Marilynn Rothen, Marleen Temmerman, Kathleen Paul
The Vaginal Microflora In Relation To Gingivitis, Rutger Persson, Jane Hitti, Rita Verhelst, Mario Vaneechoutte, Rigmor Persson, Regula Hirschi, Marianne Weibel, Marilynn Rothen, Marleen Temmerman, Kathleen Paul
Obstetrics and Gynaecology, East Africa
Background: Gingivitis has been linked to adverse pregnancy outcome (APO). Bacterial vaginosis (BV) has been associated with APO. We assessed if bacterial counts in BV is associated with gingivitis suggesting a systemic infectious susceptibilty.
Methods: Vaginal samples were collected from 180 women (mean age 29.4 years, SD ± 6.8, range: 18 to 46), and at least six months after delivery, and assessed by semi-quantitative DNA-DNA checkerboard hybridization assay (74 bacterial species). BV was defined by Gram stain (Nugent criteria). Gingivitis was defined as bleeding on probing at ≥ 20% of tooth sites.
Results: A Nugent score of 0–3 (normal vaginal …
Chronic Subjective Dizziness (Csd) Vs. Conversion Disorder: Discussion Of Clinical Findings And Rehabilitation., Julie A. Honaker, Jane M. Gilbert, Jeffrey P. Staab
Chronic Subjective Dizziness (Csd) Vs. Conversion Disorder: Discussion Of Clinical Findings And Rehabilitation., Julie A. Honaker, Jane M. Gilbert, Jeffrey P. Staab
Department of Special Education and Communication Disorders: Faculty Publications
PURPOSE: Audiologists frequently encounter patients who complain of chronic dizziness or imbalance, in the absence of active vestibular or neurological deficits. Knowledge about conditions that cause this clinical presentation will allow audiologists to make important contributions to accurate diagnosis and effective management of these patients. This article reviews two such conditions, chronic subjective dizziness (CSD) and conversion disorder. METHOD: A case of CSD and another of conversion disorder are presented with a literature review of their clinical presentations, key diagnostic features, and treatment strategies. The role of the audiologist in assessing patients with these conditions and facilitating appropriate treatment referrals …
Comparison Of Cephalometric Norms Of Esthetically Pleasing Faces, Attiya Jawaid Shaikh, Arif R Alvi
Comparison Of Cephalometric Norms Of Esthetically Pleasing Faces, Attiya Jawaid Shaikh, Arif R Alvi
Section of Dental-Oral Maxillofacial Surgery
OBJECTIVE: To establish cephalometric norms of a sample of aesthetically pleasing Pakistani faces and to analyze differences and similarities with accepted standards for Caucasians.
STUDY DESIGN: Analytical cross sectional study.
PLACE AND DURATION OF STUDY: Carried out at Alvi Dental Hospital, Karachi, from August 2007 to February 2008.
METHODOLOGY: Cephalometric tracings were analyzed on a sample of 40 (20 males and 20 females) Pakistani young adults, aged 18-25 years, with full complement of permanent teeth, no previous orthodontic treatment and pleasing profile. To check the reliability of the measurements, 20 randomly selected cephalograms were retraced. None of the measurements showed …
Parental Perceptions Of Body Mass Index Referrals And Overweight School-Age Children, Misty Schwartz
Parental Perceptions Of Body Mass Index Referrals And Overweight School-Age Children, Misty Schwartz
Department of Educational Administration: Dissertations, Theses, and Student Research
It is well documented that there is a worldwide epidemic of obesity in children. To address obesity in children, emphasis must be on factors within family, school, and community environments. Although most parents and school officials are aware of the problem of overweight children, there is little data available to guide decision making about the acceptability of school-based Body Mass Index (BMI) screening and referral programs. As states mandate BMI screening and referral, parental insight is essential to determine the efficiency and effectiveness of BMI notification.
The purpose of this multiple case study was to explore the perceptions of parents …
Food For Thought: The Importance Of Nutrition For Cognitive And Physical Well-Being, Keeley M. Caviness
Food For Thought: The Importance Of Nutrition For Cognitive And Physical Well-Being, Keeley M. Caviness
Senior Honors Theses
The purpose of this paper is to examine the effects of nutrition upon the physical development and health of an individual. The main focus is on proving through the examination of various literature and the effects of specific nutrients that nutrition has a great impact on mental and physical well-being. The reasons which people give for not having proper nutrition are taken into consideration as well, and an overall conclusion can be made that nutrition is very important and should be taught to all consumers.
Prospective Associations Between Objective Measures Of Physical Activity And Fat Mass In 12-14 Year Old Children: The Avon Longitudinal Study Of Parents And Children (Alspac), Chris J. Riddoch, Sam D. Leary, Andy R. Ness, Steven N. Blair, Kevin Deere, Calum Mattocks, Alex Griffiths, George Davey Smith, Kate Tilling
Prospective Associations Between Objective Measures Of Physical Activity And Fat Mass In 12-14 Year Old Children: The Avon Longitudinal Study Of Parents And Children (Alspac), Chris J. Riddoch, Sam D. Leary, Andy R. Ness, Steven N. Blair, Kevin Deere, Calum Mattocks, Alex Griffiths, George Davey Smith, Kate Tilling
Faculty Publications
Objective: To investigate associations between physical activity at age 12 and subsequent adiposity at age 14.
Design: Prospective birth cohort study with data collected between 2003 and 2007.
Setting: Original recruitment in 1991-2 of 14,541 pregnant women living in the former County of Avon (United Kingdom).
Participants: At age 12, 11,952 children were invited to attend the research clinic. Of these, 7159 attended, and 4150 (1964 boys, 2186 girls) provided sufficient data on exposure, outcome, and confounding variables.
Main outcome measure: Fat mass at age 14, measured by dual emission x ray absorptiometry, associated with physical activity at age 12, …
School Of Medicine Academic Plan, 2009-2014
School Of Medicine Academic Plan, 2009-2014
Annual Reports - Education
The University of Connecticut School of Medicine is the only public medical school in the state and one of only three public medical schools in the New England. Consequently, it plays a pivotal role in education, research, and healthcare delivery in both the state and the region. The primary mission of the School of Medicine is education at the undergraduate, graduate, and professional levels for practitioners, teachers, and researchers, conducted in an environment of exemplary patient care, research, and public service.
Ada News - 11/16/2009, American Dental Association, Publishing Division
Ada News - 11/16/2009, American Dental Association, Publishing Division
ADA News
Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.
Environmental Health Service Learning And Water Quality In Gales Point, Belize, Ritchie D. Taylor, Shabbar Ranapurwala, Matthew Hill
Environmental Health Service Learning And Water Quality In Gales Point, Belize, Ritchie D. Taylor, Shabbar Ranapurwala, Matthew Hill
Impact Belize
Belize is a country in Central America, formerly British Honduras, located south of Mexico and east of Guatemala on the Yucatan Peninsula. As part of the WKU International Health and Human Service Learning Program, an assessment of the local water supply in Gales Point, Belize was conducted. Gales Point is a small rural village located on the Caribbean Sea coast of Belize. Belize is a developing country thus access to safe drinking water can be problematic, as was observed on the local scale. The lack of technical, managerial and financial capacity coupled with the rural location of the village, create …
Ada News - 11/02/2009, American Dental Association, Publishing Division
Ada News - 11/02/2009, American Dental Association, Publishing Division
ADA News
Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.
Μ-Opioid Receptor Agonist Injections Into The Presumed Pre-Bötzinger Complex And The Surrounding Region Of Awake Goats Do Not Alter Eupneic Breathing, K. L. Krause, Suzanne E. Neumueller, B. D. Marshall, T. Kiner, Joshua M. Bonis, Lawrence Pan, B. Qian, Hubert V. Forster
Μ-Opioid Receptor Agonist Injections Into The Presumed Pre-Bötzinger Complex And The Surrounding Region Of Awake Goats Do Not Alter Eupneic Breathing, K. L. Krause, Suzanne E. Neumueller, B. D. Marshall, T. Kiner, Joshua M. Bonis, Lawrence Pan, B. Qian, Hubert V. Forster
Physical Therapy Faculty Research and Publications
Opioids are clinically important in the alleviation of pain. An undesirable side effect of opioids is depression of breathing. Data from isolated preparations suggest this effect is due to attenuation of discharge activity of neurons in the pre-Bötzinger complex (preBötzC), a medullary area with respiratory rhythmogenic properties. The purpose of this study was to examine how [d-Ala(2),N-Me-Phe(4),Gly(5)-ol]-enkephalin (DAMGO), a μ-opioid receptor agonist, affected breathing after injection into the presumed preBötzC of the adult awake goat. We hypothesized that DAMGO would cause breathing to decrease and become irregular when injected into the presumed preBötzC and the surrounding region of the conscious …
Adding Dental Therapists To The Health Care Team To Improve Access To Oral Health Care For Children, David A. Nash
Adding Dental Therapists To The Health Care Team To Improve Access To Oral Health Care For Children, David A. Nash
Oral Health Science Faculty Publications
Oral Health in America: A Report of the Surgeon General, and the subsequent National Call to Action to Promote Oral Health, contributed significantly to raising awareness regarding the lack of access to oral health care by many Americans, especially minority and low-income populations, with resulting disparities in oral health. The problem is particularly acute among children. The current dental workforce in the United States is inadequate to meet the oral health care needs of children. It is inadequate in terms of numbers of dentists, as well as their geographic distribution, ethnicity, education, and practice orientation. Dental therapists, paraprofessionals …
Quantification Of The Individual Characteristics Of The Human Dentition, L Thomas Johnson, Thomas W. Radmer, Thomas S. Wirtz, Nicholas M. Pajewski, David E. Cadle, James Brozek, Daniel D. Blinka
Quantification Of The Individual Characteristics Of The Human Dentition, L Thomas Johnson, Thomas W. Radmer, Thomas S. Wirtz, Nicholas M. Pajewski, David E. Cadle, James Brozek, Daniel D. Blinka
School of Dentistry Faculty Research and Publications
The considerations for admissibility suggested by the Daubert trilogy challenge forensic experts to provide scientific support for opinion testimony. The defense bar has questioned the reliability of bitemark analysis. Under an award from the U. S. Department of Justice, via the Midwest Forensic Resource Center, a two-year feasibility study was undertaken to quantify six dental characteristics. Using two computer programs, the exemplars of 419 volunteers were digitally scanned, characteristics were measured, and frequency was calculated. The study demonstrates that there were outliers or rare dental characteristics in measurements. An analysis of the intra-observer and inter-observer consistency demonstrated a high degree …
Teaching Casual Random Blood Glucose Screening To Second-Year Dental Students, Thomas W. Radmer, Moawi M. Kassab, Denis P. Lynch, Martin Walsh
Teaching Casual Random Blood Glucose Screening To Second-Year Dental Students, Thomas W. Radmer, Moawi M. Kassab, Denis P. Lynch, Martin Walsh
School of Dentistry Faculty Research and Publications
In our project, archived casual random blood glucose levels of second-year dental students who were taught the mechanics of self-testing were retrieved. Material data were analyzed by calculating means, medians, standard deviations, and ranges for 161 dental students screened by this casual and random self-monitoring of blood glucose levels as described by the American Diabetes Association’s 2008 Standards of Medical Care in Diabetes. Three types of data were assessed in this study. The first was the casual blood glucose levels of second-year dental students. The second was the data retrieved from student questionnaires regarding the value of teaching casual random …
A Review Of The National Physical Activity Plans Of Six Countries, Daniel B. Bornstein, Russell R. Pate, Michael Pratt
A Review Of The National Physical Activity Plans Of Six Countries, Daniel B. Bornstein, Russell R. Pate, Michael Pratt
Faculty Publications
Background: Architects of the United States national physical activity plan can benefit from a thorough understanding of national physical activity plans from other nations. The purpose of this paper was to search for and analyze comprehensive national physical activity plan documents that can best inform the development of the U.S. plan. Methods: Electronic databases were searched for national physical activity plan documents, yielding 252 documents from 56 countries. After eliminating documents that were not written in English, did not address physical activity primarily, and did not meet our definition of a national physical activity plan, we were left with physical …
A Critical Appraisal Of Guidelines For Antenatal Care: Components Of Care And Priorities In Prenatal Education, Lisa Hanson, Leona Vandevusse, Joyce Roberts, Amanda Forristal
A Critical Appraisal Of Guidelines For Antenatal Care: Components Of Care And Priorities In Prenatal Education, Lisa Hanson, Leona Vandevusse, Joyce Roberts, Amanda Forristal
College of Nursing Faculty Research and Publications
There are a variety of published prenatal care (PNC) guidelines that claim a scientific basis for the information included. Four sets of PNC guidelines published between 2005 and 2009 were examined and critiqued. The recommendations for assessment procedures, laboratory testing, and education/counseling topics were analyzed within and between these guidelines. The PNC components were synthesized to provide an organized, comprehensive appendix that can guide providers of antepartum care. The appendix may be used to locate which guidelines addressed which topics to assist practitioners to identify evidence sources. The suggested timing for introducing and reinforcing specific topics is also presented in …
The Effects Of Field-Of-View And Patient Size On Ct Numbers From Cone-Beam Computed Tomography., Katrina Y T Seet, Arvand Barghi, Slav Yartsev, Jacob Van Dyk
The Effects Of Field-Of-View And Patient Size On Ct Numbers From Cone-Beam Computed Tomography., Katrina Y T Seet, Arvand Barghi, Slav Yartsev, Jacob Van Dyk
Oncology Publications
Cone-beam computed tomography (CBCT) is used for patient alignment before treatment and is ideal for use in adaptive radiotherapy to account for tumor shrinkage, organ deformation and weight loss. However, CBCT images are prone to artifacts such as streaking and cupping effects, reducing image quality and CT number accuracy. Our goal was to determine the optimum combination of cone-beam imaging options to increase the accuracy of image CT numbers. Several phantoms with and without inserts of known relative electron densities were imaged using the Varian on-board imaging system. It was found that CT numbers are most influenced by the selection …
Ada News - 10/19/2009, American Dental Association, Publishing Division
Ada News - 10/19/2009, American Dental Association, Publishing Division
ADA News
Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.
Peer-Led, School-Based Nutrition Education For Young Adolescents: Feasibility And Process Evaluation Of The Teens Study, Mary Story, Leslie A. Lytle, Amanda Birnbaum, Cheryl L. Perry
Peer-Led, School-Based Nutrition Education For Young Adolescents: Feasibility And Process Evaluation Of The Teens Study, Mary Story, Leslie A. Lytle, Amanda Birnbaum, Cheryl L. Perry
Department of Public Health Scholarship and Creative Works
Peer education has become a popular strategy for health promotion interventions with adolescents, but it has not been used widely in school‐based nutrition education. This paper describes and reports on the feasibility of the peer leader component of school‐based nutrition intervention for young adolescents designed to increase fruit and vegetable intakes and lower-fat foods. About 1,000 seventh‐grade students in eight schools received the nutrition intervention. Of these, 272 were trained as peer leaders to assist the teacher in implementing the activities. Results from a multicomponent process evaluation based on peer leader and classroom student feedback, direct classroom observation, and teacher …
Ada News - 10/05/2009, American Dental Association, Publishing Division
Ada News - 10/05/2009, American Dental Association, Publishing Division
ADA News
Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.
Primary Language Spoken At Home And Children's Dental Service Utilization In The United States, Matthew Noyce, Aniko Szabo, Nicholas M. Pajewski, Scott Jackson, T. Gerard Bradley, Christopher Okunseri
Primary Language Spoken At Home And Children's Dental Service Utilization In The United States, Matthew Noyce, Aniko Szabo, Nicholas M. Pajewski, Scott Jackson, T. Gerard Bradley, Christopher Okunseri
School of Dentistry Faculty Research and Publications
Objective: Language barriers have been well documented as a contributing factor to disparities in the receipt of medical services, especially for Hispanic children. However, there is a paucity of information on the effect of language barriers on children's dental service utilization. We examined the association of primary language spoken at home with the receipt of preventive and routine dental care for children in the United States. Methods: We analyzed data from the Medical Expenditure Panel Survey (2002-2004), which contains data on 21,049 children weighted to represent 75.8 million children nationally. Results: Among children aged 1-18 years, 13 percent spoke a …
Somnoforme: A Century After The Introduction Of The "Ideal" Anesthetic Gas, James W. Heitz, Md
Somnoforme: A Century After The Introduction Of The "Ideal" Anesthetic Gas, James W. Heitz, Md
Department of Anesthesiology Faculty Papers
Since the introduction of ether as a general anesthetic, there has been a continuous quest to develop the ideal anesthetic gas. The attributes of the ideal anesthetic gas have evolved over time. At the beginning of the 20th century, the search for the ideal anesthetic was focused upon finding an anesthetic gas with rapid inhalation induction and rapid emergence that could be delivered without cumbersome apparatus and would have limited potential for toxicity. Somnoforme was a mixture of ethyl chloride, methyl chloride, and ethyl bromide designed to provide powerful efficacy with low potential for side effects by blending of several …
Sour Ageusia In Two Individuals Implicates Ion Channels Of The Asic And Pkd Families In Human Sour Taste Perception At The Anterior Tongue., Taufiqul Huque, Beverly J Cowart, Luba Dankulich-Nagrudny, Edmund A Pribitkin, Douglas L Bayley, Andrew I Spielman, Roy S Feldman, Scott A Mackler, Joseph G Brand
Sour Ageusia In Two Individuals Implicates Ion Channels Of The Asic And Pkd Families In Human Sour Taste Perception At The Anterior Tongue., Taufiqul Huque, Beverly J Cowart, Luba Dankulich-Nagrudny, Edmund A Pribitkin, Douglas L Bayley, Andrew I Spielman, Roy S Feldman, Scott A Mackler, Joseph G Brand
Department of Otolaryngology - Head and Neck Surgery Faculty Papers
BACKGROUND: The perception of sour taste in humans is incompletely understood at the receptor cell level. We report here on two patients with an acquired sour ageusia. Each patient was unresponsive to sour stimuli, but both showed normal responses to bitter, sweet, and salty stimuli.
METHODS AND FINDINGS: Lingual fungiform papillae, containing taste cells, were obtained by biopsy from the two patients, and from three sour-normal individuals, and analyzed by RT-PCR. The following transcripts were undetectable in the patients, even after 50 cycles of amplification, but readily detectable in the sour-normal subjects: acid sensing ion channels (ASICs) 1a, 1beta, 2a, …