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Incidence Of Allergic Reactions To Cefazolin In Patients With Penicillin Allergy Undergoing Operative Repair Of Pelvis Or Extremity Fracture, Hans Drawbert, Laclan Anderson, Marisa Fat, John Riehl Jan 2025

Incidence Of Allergic Reactions To Cefazolin In Patients With Penicillin Allergy Undergoing Operative Repair Of Pelvis Or Extremity Fracture, Hans Drawbert, Laclan Anderson, Marisa Fat, John Riehl

North Texas Research Forum 2025

Introduction Surgical site infections (SSI) account for 20% of all healthcare associated infections with an estimated yearly cost of $3.3 billion in the US alone (1). Cefazolin (Ancef) is a commonly used prophylactic antibiotic in orthopaedic surgery and has been shown to reduce SSI compared to other antibiotics, but potential cross-reactivity in patients with a penicillin allergy (PA) leads to concerns regarding the safety of cefazolin administration. This study evaluates the incidence of allergic reactions to cefazolin in patients undergoing orthopaedic surgery with a PA. Methods A retrospective cross-sectional database review study was conducted. Patients aged 18 or over who …


The Utilization Of Podcasts And Test Enhanced Learning In Paramedic And Resident Education, Vincente Loera Jan 2025

The Utilization Of Podcasts And Test Enhanced Learning In Paramedic And Resident Education, Vincente Loera

Gulf Coast Division GME Research Day 2025

No abstract provided.


Painfully Obvious: Expanding Inpatient Buprenorphine For Opioid Use Disorder, Aline Levy-Sitnoveter, Mark Delic, Jonathan Aires Pinheiro, Eleana Estrella, Sankalp Goberdhan, Lauren Hundley, Richard Henriquez, Shamol Williams Jan 2025

Painfully Obvious: Expanding Inpatient Buprenorphine For Opioid Use Disorder, Aline Levy-Sitnoveter, Mark Delic, Jonathan Aires Pinheiro, Eleana Estrella, Sankalp Goberdhan, Lauren Hundley, Richard Henriquez, Shamol Williams

North Florida Division GME Research Day 2025

No abstract provided.


Complete Gastric Transection After Blunt Force Trauma, Sydney Parker, Sophia Jimenez, Riley Blanton, Samprit Karra, Alejandro Garcia Jan 2025

Complete Gastric Transection After Blunt Force Trauma, Sydney Parker, Sophia Jimenez, Riley Blanton, Samprit Karra, Alejandro Garcia

Central & West Texas and San Antonio GME Research Day 2025

No abstract provided.


Albuterol: An Often-Forgotten Cause Of Lactic Acidosis, Sania Moonnumackel, Sameera Muqueet, Machaiah Madhrira Jan 2025

Albuterol: An Often-Forgotten Cause Of Lactic Acidosis, Sania Moonnumackel, Sameera Muqueet, Machaiah Madhrira

North Texas Research Forum 2025

Introduction Lactic acid (LA) is a commonly used biomarker and is often indicative of severity of disease in critically ill patients. Lactic acidosis which is defined as LA > 4.0 can be divided into two categories: Type A which is the more common type is caused by systemic tissue hypoperfusion most likely due to shock and Type B which is caused by impairment of cellular metabolism and or decreased clearance of LA. An important cause of Type B lactic acidosis is medications including acetaminophen, anti-retroviral drugs, antibiotics and beta-adrenergic agonists including albuterol. Often patients with severe lactic acidosis are given fluid …


Polymyalgia Rheumatica Secondary To Pembrolizumab, Farigol Hakem Zadeh, Nikita Shah, Miguel E. Rodriguez Jan 2025

Polymyalgia Rheumatica Secondary To Pembrolizumab, Farigol Hakem Zadeh, Nikita Shah, Miguel E. Rodriguez

North Florida Division GME Research Day 2025

No abstract provided.


Comparative Outcomes Of Peroral Endoscopic Myotomy Vs. Heller Myotomy In Achalasia Patients, Mohammad Abuassi, Carson Creamer, Harsimran Kalsi, Kobina Essilfie-Quaye, Tony S. Brar, Yaseen Perbtani Jan 2025

Comparative Outcomes Of Peroral Endoscopic Myotomy Vs. Heller Myotomy In Achalasia Patients, Mohammad Abuassi, Carson Creamer, Harsimran Kalsi, Kobina Essilfie-Quaye, Tony S. Brar, Yaseen Perbtani

North Florida Division GME Research Day 2025

No abstract provided.


Probiotics For The Primary Prevention Of Inpatient, Antibiotic-Associated Clostridioides Difficile Infection: A Multi-Center, Retrospective Study, Cooper Josephs, Taylor Templeton-Jager, Julie Worthington Jan 2025

Probiotics For The Primary Prevention Of Inpatient, Antibiotic-Associated Clostridioides Difficile Infection: A Multi-Center, Retrospective Study, Cooper Josephs, Taylor Templeton-Jager, Julie Worthington

South Atlantic Division GME Research Day 2025

No abstract provided.


What Newly Updated Variables Are Correlated With Colon Cancer Incidence And Death Rates In Florida?, Cody Steed, Julia Fashner Jan 2025

What Newly Updated Variables Are Correlated With Colon Cancer Incidence And Death Rates In Florida?, Cody Steed, Julia Fashner

East Florida Division GME Research Day 2025

No abstract provided.


Delayed Diagnosis Of Severe Hypercalcemia Due To Parathyroid Adenoma In A 59-Year-Old Woman Without Primary Care, Adeola Togun Jan 2025

Delayed Diagnosis Of Severe Hypercalcemia Due To Parathyroid Adenoma In A 59-Year-Old Woman Without Primary Care, Adeola Togun

East Florida Division GME Research Day 2025

No abstract provided.


Mcl Or Dlbcl - Make Right Choice!, Mohammed Shafeay, Mirza Baig, Astrid Sacasa, Ram Madasu, Delbert Benzenhafer, Alexey Glazyrin Jan 2025

Mcl Or Dlbcl - Make Right Choice!, Mohammed Shafeay, Mirza Baig, Astrid Sacasa, Ram Madasu, Delbert Benzenhafer, Alexey Glazyrin

East Florida Division GME Research Day 2025

No abstract provided.


Primary Cardiac Lymphoma: A Rare Diagnosis, Astrid Sacasa, Betty Kirimi, Mohtashim Naeem, Susana Ferra Jan 2025

Primary Cardiac Lymphoma: A Rare Diagnosis, Astrid Sacasa, Betty Kirimi, Mohtashim Naeem, Susana Ferra

East Florida Division GME Research Day 2025

No abstract provided.


Splenic Laceration And Hematoma In The Setting Of Acute Pancreatitis And Decompensated Cirrhosis, Rasmeet Kaur, Eric Romero, Oscar Garcia Jan 2025

Splenic Laceration And Hematoma In The Setting Of Acute Pancreatitis And Decompensated Cirrhosis, Rasmeet Kaur, Eric Romero, Oscar Garcia

Central & West Texas and San Antonio GME Research Day 2025

No abstract provided.


Thyrotoxic Periodic Paralysis And Pesticide Exposure, Vinh Ngo, Huy Vuong, Oscar Garcia Jan 2025

Thyrotoxic Periodic Paralysis And Pesticide Exposure, Vinh Ngo, Huy Vuong, Oscar Garcia

Central & West Texas and San Antonio GME Research Day 2025

No abstract provided.


Acute Respiratory Compromise Secondary To Superior Vena Cava Syndrome In A Sickle Cell Patient. Vaso-Occlusion Triggered By Steroids?, Ashley Diaz, Priya Mohan, Abhishek Sharma, David Zarabanda, Raiko Diaz Jan 2025

Acute Respiratory Compromise Secondary To Superior Vena Cava Syndrome In A Sickle Cell Patient. Vaso-Occlusion Triggered By Steroids?, Ashley Diaz, Priya Mohan, Abhishek Sharma, David Zarabanda, Raiko Diaz

East Florida Division GME Research Day 2025

No abstract provided.


Myxoid Variant: An Unusual Presentation Of Low-Grade Epithelioid Mesothelioma, Racquel Fournet, Robert Bender, Rohit Jaishankar, Alexey Glazyrin Jan 2025

Myxoid Variant: An Unusual Presentation Of Low-Grade Epithelioid Mesothelioma, Racquel Fournet, Robert Bender, Rohit Jaishankar, Alexey Glazyrin

East Florida Division GME Research Day 2025

No abstract provided.


Single-Agent And Short-Course Antibiotic Result In Optimal Outcomes For The Nonoperative Management Of Perforated Peptic Ulcer, Dimitri Sagwo Tchienga, Ramon Gil, Robyn Meadows, Shaikh Hai Jan 2025

Single-Agent And Short-Course Antibiotic Result In Optimal Outcomes For The Nonoperative Management Of Perforated Peptic Ulcer, Dimitri Sagwo Tchienga, Ramon Gil, Robyn Meadows, Shaikh Hai

East Florida Division GME Research Day 2025

No abstract provided.


​Comparison Of Diagnostic Accuracy Of Ct And Spect-Ct In Pseudarthrosis Detection: A Systematic Review And Meta-Analysis​, Nicholas Schiller, Miguel Cartagena-Reyes, Elyette Lugo, Diego Lopes De Lima, Brett Schlifka, Milad Alam Jan 2025

​Comparison Of Diagnostic Accuracy Of Ct And Spect-Ct In Pseudarthrosis Detection: A Systematic Review And Meta-Analysis​, Nicholas Schiller, Miguel Cartagena-Reyes, Elyette Lugo, Diego Lopes De Lima, Brett Schlifka, Milad Alam

East Florida Division GME Research Day 2025

No abstract provided.


Performance In Grading Of Well Differentiated Pancreatic Neuroendocrine Tumors (Wdpannet) Using The 2019 World Health Organization (Who) Classification Of Tumors Of The Digestive System. Experience Of A Community Teaching Hospital., Astrid Sacasa, Gul Emek Wymer, Susana Ferra Jan 2025

Performance In Grading Of Well Differentiated Pancreatic Neuroendocrine Tumors (Wdpannet) Using The 2019 World Health Organization (Who) Classification Of Tumors Of The Digestive System. Experience Of A Community Teaching Hospital., Astrid Sacasa, Gul Emek Wymer, Susana Ferra

East Florida Division GME Research Day 2025

CONTEXT: The WHO Classification of Tumors of the Digestive System (2019) categorizes WDPanNETs as grade 1 (G1), grade 2 (G2) or grade 3 (G3) by mitotic count and proliferative index (KI67). We examined the performance of pathologists and pathology trainees in grading WDPanNET according to the 2019 WHO Classification.

DESIGN: One H&E and KI-67 slides of eleven WDPanNET cases from our 2023 archives (7 G1, 1 G2 and 3 G3) were blindly evaluated by 2 junior residents (PGY-1), 2 senior residents (PGY-3), 2 pathologists without formal gastrointestinal training (NOGIP) and 2 pathologists with formal gastrointestinal training (GIP), provided with the …


Post-Operative Afib After Cabg: A Retrospective Analysis, Leonardo A. Almaguer Gongora, Myrna E. Reinhardt, Manuel Jimenez, Luis E. Remedios Carbonell, Daniel Padron, Priya Mohan, Juliette Camejo, Bernardo Reyes Jan 2025

Post-Operative Afib After Cabg: A Retrospective Analysis, Leonardo A. Almaguer Gongora, Myrna E. Reinhardt, Manuel Jimenez, Luis E. Remedios Carbonell, Daniel Padron, Priya Mohan, Juliette Camejo, Bernardo Reyes

East Florida Division GME Research Day 2025

No abstract provided.


The Face-Off Between Two Mimics: Lupus And Tuberculosis, Fnu Swatisikta, Nang Kham, Ali Chaudhry Jan 2025

The Face-Off Between Two Mimics: Lupus And Tuberculosis, Fnu Swatisikta, Nang Kham, Ali Chaudhry

East Florida Division GME Research Day 2025

INTRODUCTION Both lupus and Mycobacterium tuberculosis can affect any organ and can present with non-specific multi-organ involvement. In a patient with lupus, it may be difficult to distinguish between a lupus flare and a mycobacterial infection.

CASE A 28-year-old female with a history of systemic lupus erythematosus (SLE), (anti-Smith and ds-DNA positive), presented with knee swelling, chest and abdominal pain. She had elevated inflammatory markers, hyperkalemia with AKI. CT chest showed bilateral lung micronodules and patchy opacity. The patient had been on long-term steroids, mycophenolate, and hydroxychloroquine. Belimumab and voclosporin were initiated after a recent kidney biopsy revealed class 4 …


Working With Foster Families: What Providers Should Know, The Rees-Jones Center For Foster Care Excellence Jan 2025

Working With Foster Families: What Providers Should Know, The Rees-Jones Center For Foster Care Excellence

White Papers and Policy Briefs

Foster parents play a vital, yet often challenging role in the lives of children who have experienced trauma and instability. Navigating the healthcare system for children in foster care can be particularly complex and overwhelming, requiring understanding, collaboration, and a unique approach from healthcare professionals. This page offers insights and practical ideas for healthcare professionals to effectively support foster parents, ultimately contributing to the well-being of the children in their care.

For questions about this publication or others, please email [email protected]

childrens.com/fostercare


Ensuring The Health And Well-Being Of Children After Adoption, The Rees-Jones Center For Foster Care Excellence Jan 2025

Ensuring The Health And Well-Being Of Children After Adoption, The Rees-Jones Center For Foster Care Excellence

White Papers and Policy Briefs

Children in foster care have higher rates of health concerns and healthcare utilization than their peers who have not experienced foster care. For example, one study found that children in foster care had 2.5- and 2.3-times higher odds of having a mental health diagnosis and developmental disability diagnosis, respectively. Data on our patient population supports these findings, revealing that 70.4% of our patients had chronic or complex chronic health conditions.

For questions about this publication or others, please email [email protected]

childrens.com/fostercare


Association Between Neighborhood-Level Social Vulnerability And Hypertension Outcomes, John E. Brush Jr., Chungsoo Kim, Yuntian Liu, Xin Xin, Chenxi Huang, Iris J. Lundy, Jordan R. Asher, Mitsuaki Sawano, Patrick Young, Jacob Mcpadden, Mark Anderson, John S. Burrows, Harlan M. Krumholz, Yuan Lu Jan 2025

Association Between Neighborhood-Level Social Vulnerability And Hypertension Outcomes, John E. Brush Jr., Chungsoo Kim, Yuntian Liu, Xin Xin, Chenxi Huang, Iris J. Lundy, Jordan R. Asher, Mitsuaki Sawano, Patrick Young, Jacob Mcpadden, Mark Anderson, John S. Burrows, Harlan M. Krumholz, Yuan Lu

Department of Medicine Faculty Publications

Background

Neighborhood-level social vulnerability is associated with hypertension prevalence and severity and with cardiovascular complications in conditions other than hypertension, but its association with cardiovascular complications in patients with hypertension is understudied.

Objectives

The aim of the study was to examine how the neighborhood-level social vulnerability index (SVI) influences cardiovascular outcomes in a large, diverse cohort of patients with hypertension.

Methods

We used electronic health data to examine the association between census tract-level rankings for the SVI with a composite endpoint of incident myocardial infarction, congestive heart failure, or stroke.

Results

In a longitudinal cohort of 330,972 patients with hypertension …


Do Patients Who Receive Dexmedetomidine As An Adjunct To Spinal Anesthesia For Cesarean Delivery Achieve Longer Block Duration Compared To Those Who Receive Spinal Anesthesia With Local Anesthetic Alone?, Liana S. Garrison Jan 2025

Do Patients Who Receive Dexmedetomidine As An Adjunct To Spinal Anesthesia For Cesarean Delivery Achieve Longer Block Duration Compared To Those Who Receive Spinal Anesthesia With Local Anesthetic Alone?, Liana S. Garrison

Theses, Dissertations and Capstones

Problem Statement: Cesarean delivery is associated with significant postoperative pain, typically managed with spinal anesthesia using a local anesthetic. While opioids are often added as adjuncts, the addition of dexmedetomidine, an alpha-2 agonist, has emerged as a potential alternative that may enhance the efficacy of the spinal block in terms of pain management, potentially improving block duration and quality compared to local anesthetic alone.

Methodology: A literature review was conducted on the use of dexmedetomidine as an adjunct to spinal anesthesia for patients undergoing cesarean sections. Databases used for the search included PubMed, CINAHL Complete, and MEDLINE. The keywords used …


Practice Patterns In Pediatric And Adult Dysphagia: Implications For Clinical Training, Jane Grothaus, Kaitlyn Hill, Marlee Nebesniak, Anastasia Raymer Jan 2025

Practice Patterns In Pediatric And Adult Dysphagia: Implications For Clinical Training, Jane Grothaus, Kaitlyn Hill, Marlee Nebesniak, Anastasia Raymer

Speech-Language Pathology Faculty Publications

Objective: Most speech language pathologists (SLPs) receive training to work with patients with swallowing disorders in graduate school, focusing primarily on adult dysphagia. Although SLPs share common foundational knowledge and skills for adult and pediatric dysphagia populations, there are considerable differences in these two specialized areas of practice. We aimed to query SLPs’ practice patterns for dysphagia assessment and management for adults and pediatric populations to consider differences and guide training efforts.

Methods: We distributed two comprehensive anonymous surveys to explore practice patterns of SLPs who provide assessment and management of dysphagia for adult or pediatric populations. The 118 respondents, …


An Observational Study Of Discourse Tasks And Running Speech Sampling In The Assessment Of Paediatric Voice Quality, Victoria Reynolds, Kristin Scavo-Smith, Kate Oteng-Bediako, Sophie Scanlon Jan 2025

An Observational Study Of Discourse Tasks And Running Speech Sampling In The Assessment Of Paediatric Voice Quality, Victoria Reynolds, Kristin Scavo-Smith, Kate Oteng-Bediako, Sophie Scanlon

Speech-Language Pathology Faculty Publications

Introduction

Running speech sampling is an essential component of a paediatric voice evaluation, in that it should provide the examiner with a representative vocal sample of the child's everyday voice use outside of the clinic setting. Current speech sampling practices, consisting of reading tasks, informal conversation sampling and the voice question ('Tell me about your voice problem'), may not elicit consistent samples or samples of sufficient length to allow the examiner to make a reliable and valid judgement about vocal quality. The aim of this study is to compare the voice quality of children produced in response to existing running …


Exploring The Clinical Profiles And Management Of Juvenile Dermatomyositis In Africa: A Survey Of African Rheumatology Care Providers, Jessica Perfetto, Laura B. Lewandowski, Dawn M. Wahezi, Vanessa Ogega, Joan Ahimbisibwe, Kate Webb, Christiaan Scott, Angela Migowa Jan 2025

Exploring The Clinical Profiles And Management Of Juvenile Dermatomyositis In Africa: A Survey Of African Rheumatology Care Providers, Jessica Perfetto, Laura B. Lewandowski, Dawn M. Wahezi, Vanessa Ogega, Joan Ahimbisibwe, Kate Webb, Christiaan Scott, Angela Migowa

Paediatrics and Child Health, East Africa

Background: There are limited studies of juvenile dermatomyositis (JDM) in low and middle-income countries (LMIC). Many demonstrate delays to care, high prevalence of severe manifestations, and high mortality. Given the disease-associated damage with JDM, understanding JDM in Africa further is critical. Our objectives are to understand the burden of JDM in Africa and provider access to diagnostic tools and therapy through survey methodology.

Methods: A survey (available in English and French) was distributed via WhatsApp to 363 total members of the African League of Associations for Rheumatology (AFLAR; n = 233) and Paediatric Society of the African League Against Rheumatism …


Staphylococcus Aureus Encodes Four Differentially Regulated Pyruvate Transporters, Jennifer L. Endres, Cleofes Sarmiento, William Xiao, Marat R. Sadykov, Kenneth W. Bayles, Mckenzie K. Lehman Jan 2025

Staphylococcus Aureus Encodes Four Differentially Regulated Pyruvate Transporters, Jennifer L. Endres, Cleofes Sarmiento, William Xiao, Marat R. Sadykov, Kenneth W. Bayles, Mckenzie K. Lehman

Journal Articles: Pathology and Microbiology

The success of Staphylococcus aureus as a pathogen is attributable, in part, to its ability to exploit the diverse nutrient sources available during infection. Critical to this success are the pathways involving pyruvate that serve as a nexus for energy production, oxidative metabolism, and biosynthetic processes. When available, bacteria acquire pyruvate from the environment to fuel growth. Recently, LrgAB was identified as a pyruvate transporter under microaerobic conditions, leading us to speculate that S. aureus encodes other pyruvate transporters that are active during aerobic growth. In this study, we used the toxic pyruvate analog, 3-fluoropyruvic acid (3-FP), to isolate mutants …


Comprehensive Characterization Of Chronic Midazolam Exposure On Neonates And Long-Term Neurodevelopment, Nghi M. Nguyen, Pranavi Athota, Adrian Flores, Andrew Trease, Daniel Meyer, Vamsi K. Singu, Chandan Krishnamoorthy, Victoria L. Schaal, Reeyan Bhakat, Kunal Sualy, Sathish Kumar Natarajan, Kelly L. Stauch, Sowmya V. Yelamanchili, Gurudutt Pendyala Jan 2025

Comprehensive Characterization Of Chronic Midazolam Exposure On Neonates And Long-Term Neurodevelopment, Nghi M. Nguyen, Pranavi Athota, Adrian Flores, Andrew Trease, Daniel Meyer, Vamsi K. Singu, Chandan Krishnamoorthy, Victoria L. Schaal, Reeyan Bhakat, Kunal Sualy, Sathish Kumar Natarajan, Kelly L. Stauch, Sowmya V. Yelamanchili, Gurudutt Pendyala

Journal Articles: Anesthesiology

Approximately 1 in 10 U.S. newborns are born preterm (< 37 weeks of gestation), facing risks of low birth weight, respiratory and birth deficits often requiring surgery, mechanical ventilation, and prolonged sedation. Such long-term exposure to sedatives in these babies can potentially pose neurodevelopmental risks and can further impact changes later in life. The present study focused on midazolam (MDZ), a benzodiazepine class drug commonly used as sedative in the neonatal intensive care unit (NICU). Using a robust preclinical rodent model mimicking chronic MDZ exposure, we did a comprehensive characterization on the phenotypic, molecular, biochemical, and behavioral outcomes in these exposed neonates across key developmental milestones. Our findings indicate that long-term MDZ exposure during the neonatal period negatively affects physical attributes in early childhood. While adult bodyweights between control and MDZ-exposed rats remain comparable, the MDZ rats exhibit accelerated and robust weight gain, potentially indicating a predisposition for binge eating behavior. Additionally, dopamine release in MDZ-exposed rats is markedly reduced in adulthood. Elevated levels of pro-inflammatory cytokines and growth factors in the brain during adulthood suggest a shift in development due to early MDZ exposure. Further, trends of heightened anxiety-like behavior and reduced social interaction during early adolescence compared to other stages were observed. Collectively, our study provides a comprehensive assessment of how long-term MDZ exposure during neonatal stages impacts outcomes throughout life, laying the foundation for understanding mechanisms that contribute to neurodevelopmental complications associated with long-term MDZ use in neonates.