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Evaluation Of Peutz-Jeghers Syndrome In A Family, Kayhan Ozkan

Henry Ford Hospital Medical Journal

Five cases of Peutz-Jeghers syndrome in one family have been studied, and a review of the history and features of the syndrome are presented. This syndrome was detected in four of six siblings and in the father. Three family members underwent surgery after small-bowel obstruction was diagnosed. A gastric polyp was removed from a fourth family member. Rectal bleeding dominated the clinical picture in two patients. Colonic polyps were also found in the three patients who had small-bowel polyps. One of the four affected siblings had mucocutaneous pigmentation, but no evidence of intestinal polyps was detected. The five affected family …

Orbital Metastasis With Enophthalmos: A Review Of The Literature, David M. Reifler

Henry Ford Hospital Medical Journal

Orbital metastasis is associated with enophthalmos in up to one third of all cases. After analyzing the clinical and pathologic features In 25 reported cases of enophthalmic orbital metastasis, the condition was found to almost exclusively affect females, usually in the 60 to 70 age group. The right orbit was the most commonly affected. The primary lesion was located in the breast in 19 (76%) cases and in the abdomen in 6 (24%) cases. In one third of the cases, the manifestations of the orbital metastasis were recognized before diagnosing the primary lesion. The most common presenting features were diplopia …

Childhood Lead Poisoning, Raj P. Warrier, Jan Waisanen, Sam R. Kottamasu, Sayeed Sultana, K. Ratnakar Kini, William L. Kestenberg, John Strauthers, Craig Foreback

Henry Ford Hospital Medical Journal

Although lead encephalopathy is rare, lead intoxication continues to be a significant problem in Detroit. Neuropsychological effects may occur even at low levels of lead. Since treatment of lead poisoning consists of a painful series of injections, it is imperative that more attention be given to the prevention of this disease. To confirm the magnitude of the problems, our experience with lead poisoning during a three-year period at Henry Ford Hospital's Pediatric Department is reviewed.

Primary Hyperparathyroidism: Changing Patterns In Presentation And Treatment Decisions In The Eighties, D. Sudhaker Rao

Henry Ford Hospital Medical Journal

No abstract provided.

Vital Signs, Fall 1985, Boonshoft School Of Medicine

Vital Signs

A twenty eight page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, alumni profiles, class notes, and more.

The Effectiveness Of Stimulation Therapy For The Cognitively Impaired Elderly, Sylvia H. Old

Community & Environmental Health Theses & Dissertations

The effectiveness of stimulation therapy for the cognitively impaired elderly living in an institution was assessed. Residents with varying degrees of cognitive impairment were treated with twenty, thirty-minute daily periods of reality orientation, reminiscence, resocialization, remotivation, and other stimulating therapies and were compared with a control group_ receiving no intervention. Treatment effects were assessed with a variety of instruments reflecting functioning across several domains. Included were ability to perform both basic self-care functions and activities of daily living, cognitive performance, affect, and satisfaction with the care received and the living environment in the nursing home. The experimental group was divided …

Middle Cerebral Artery Aneurysm: A Computer Model, G. Austin, R. Gaskell

The Dr. George M. Austin Neurology Research Collection

Middle Cerebral Artery Aneurysm: A Computer Model, Program Abstract, 8th Int. Congress of Neurological Surgery - Toronto, Canada, July 7-11, 1985

Mammography: Still The Imaging Standard, Cathrine E. Keller, A. Christine Watt

Henry Ford Hospital Medical Journal

Breast carcinoma is the leading cause of cancer death in women in the United States. Recent technological advances have resulted in multiple imaging methods designed to improve the detection of breast cancer. These imaging methods are discussed. Mammography remains the most accurate imaging method used to evaluate the breast. Automated waterpath whole-breast ultrasound is the most useful adjunctive examination to mammography at the present time.

Computed Tomographic And Sonographic Characterizations Of Central Nervous System Masses, Beatrice L. Madrazo, William P. Sanders, Bharat Mehta, Manuel Dujovny, Michael A. Sandler, David P. Chason, Jacob L. Chason, James I. Ausman

Henry Ford Hospital Medical Journal

We present our experience with 15 central nervous system masses evaluated preoperatively with computed tomography and by intraoperative sonography. Cysts were seen as sharply circumscribed, thin-walled masses, near water density by computed tomography, and echo-free by sonography. Inflammatory masses were well demarcated by tomography with areas of edema and ring enhancement but were poorly marginated and variable in appearance by sonography. Primary brain tumors presented as round, solid or complex masses best evaluated by intraoperative sonography in those cases where poor contrast enhancement resulted in limited characterization of the mass by computed tomography. Our experience suggests a very high degree …

Current Concepts Of Metabolic Functional Imaging With Positron Emitters, John W. Keyes Jr.

Henry Ford Hospital Medical Journal

Positron emitting radionuclides have unique properties that make them nearly ideal as radioactive tracers for in vivo metabolic studies. Using positron emission tomographic (PET) scanning and positron-labeled radiopharmaceuticals, one can study local glucose metabolism in tissues, blood flow, oxygen utilization, protein synthesis, and many other functions noninvasively in normal subjects and patients who have various diseases. A review of some of these techniques and the relative advantages and problems associated with the PET approach is presented.

The Incidence Of Calculi In Focal Nonshadowing Echogenicity In The Gallbladder, Michael A. Sandler, Eileen M. Biunno, Martin L. Gross, Beatrice L. Madrazo

Henry Ford Hospital Medical Journal

Sonography is valuable in the accurate diagnosis of gallstones. All but the smallest stones attenuate sound, a phenomenon known as acoustic shadowing. However, when small focal nonshadowing opacities are present, the diagnostic question is whether they represent small calculi. In a four-year review of sonographic studies performed at Henry Ford Hospital, 12 patients in whom this sonographic finding was present underwent cholecystectomies, and seven had calculi (58%). If the presence of gallstones is the factor that will determine whether surgery will be performed, we recommend a repeat examination to confirm the presence of the focal opacities and to elicit acoustic …

Applications Of Magnetic Resonance Imaging In Clinical Urology, Barbara A. Demas, Hedvig Hricak

Henry Ford Hospital Medical Journal

During the past two years, the value of magnetic resonance imaging (MRI) in the diagnosis and staging of a variety of urologic neoplasms has been demonstrated, and the ability of MRI to determine sites of renal obstruction and causes of posttransplant renal failure have been reported. Its excellent soft-tissue contrast resolution has allowed accurate delineation of regional anatomy in the kidney, prostate gland, urinary bladder, urethra, uterus, and vagina. The importance of MRI in the urologic diagnosis is expected to increase as clinical imaging systems become widely available.

Nuclear Magnetic Resonance: Current And Future Clinical Applications, Jerry W. Froelich, David O. Hearshen, Robert D. Halpert, Suresh Patel

Henry Ford Hospital Medical Journal

Nuclear magnetic resonance has evolved from a laboratory analytical tool to become a rapidly developing discipline in clinical medicine. We present a brief historical overview, an introduction to the basic principles of the phenomenon, and a statement of the current status of clinical imaging. We have elected to use the traditional terminology nuclear magnetic resonance to refer to the imaging component of the field rather than the American College of Radiology (ACR) modification magnetic resonance. We do this out of respect for the founders of the field.

Predictive Value Of Radiographic Analysis Of Menton, Hyoid Bone, And The Third Cervical Vertebra Angle, Kalfred G.S. Chun

Loma Linda University Electronic Theses, Dissertations & Projects

The purpose of this study is to determine if the hyoid bone could be used as a reliable and stable reference landmark. Previous researchers have used cranial landmarks to determine the hyoid bone position. The results of these studies have shown a large variability in hyoid position. To determine the hyoid bone position, an analysis called the hyoid triangle was used. The hyoid triangle is formed by joining the cephalometric points retrognathion (the most inferior posterior point on the mandibular symphysis), hyoidale (the most superior anterior point on the body of the hyoid bone), and C3 (the most anterior inferior …

The Effects Of Blood Glucose Self-Monitoring On Self-Esteem And The Ability To Apply Knowledge About Diabetes Mellitus, Nancy-Lu F. Moul

Ellmer School of Nursing Theses & Dissertations

This study explored the effect of blood glucose self-monitoring on two dependent variables: (a) the diabetic client's self-esteem, and (b) the diabetic client's ability to apply knowledge about diabetes mellitus. The sample consisted of two groups of adult Type I diabetic clients. Group I consisted of ten clients who had been performing blood glucose self-monitoring for at least one year, and group II consisted of ten clients who had been performing urine testing for at least one year. A questionnaire was utilized which included: (a) a demographic data sheet, (b) a diabetic knowledge tool, and (c) a self-esteem tool. The …

Digest Of The Philadelphia College Of Osteopathic Medicine (Spring 1985), Philadelphia College Of Osteopathic Medicine

Digest

The Spring 1985 issue of the Digest of the Philadelphia College of Osteopathic Medicine includes the following articles:

• The President's Page
• The 94th Commencement
• Commencement Photos
• Master of Science Degrees Conferred
• Commencement Award Winners
• Families
• The Class of 1985 and Internship Hospitals
• Faculty Notes
• New Appointments
• News from the OMCP
• From the Alumni Office
• Alumni News Briefs
• Nurses Alumnae Biennial Banquet
• In Memoriam
• Coming Events

Vital Signs, Spring 1985, Boonshoft School Of Medicine

Vital Signs

A twenty eight page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, alumni profiles, class notes, and more.

Dr Frank J. Sladen: The Osler Connection, Richmond W. Smith Jr.

Henry Ford Hospital Medical Journal

No abstract provided.

A Graphical Aid To Medical Decision Making, William A. Benish

Henry Ford Hospital Medical Journal

Given knowledge of a test's sensitivity and specificity, physicians may use Bayes' theorem to appropriately modify their initial assessment of the likelihood of disease subsequent to obtaining a positive or negative test result. A graphical representation of Bayes' theorem was constructed in order to provide a simple tool to aid in the selection and interpretation of diagnostic tests.

Metastatic Bronchogenic Carcinoma Simulating Osteoarthritis, David Wendt, Paul Kvale

Henry Ford Hospital Medical Journal

No abstract provided.

Unprovoked Seizures And Myoclonus In Patients With Alzheimer's Disease, Marcia L. Morris

Journal of the Minnesota Academy of Science

Although anecdotal references commonly presume that seizures eventually occur in patients affected with dementia of the Alzheimer type (DAT), no previous American study has documented the rate of new onset, unprovoked seizures in DAT patients. There are few documented cases of the occurrence of myoclonus in autopsy-proven DAT. In a series of 83 autopsy-proven DAT cases, medical records were scrutinized for the presence of any seizure or myoclonic activity. Final evaluations were made by a neurologist. Of the 83 cases, 8 had experienced one or more unprovoked seizures after the onset of DAT. Based on age-specific incidence rates from a …

Oncolog, Volume 30, Number 04, October-December 1985, Oncolog Staff

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• Endocrine Therapy for Prostatic Cancer Can Replace Orchiectomy and Estrogens

Oncolog, Volume 30, Number 02, April-June 1985, Karel A. Dicke Md, Phd

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• Ultraviolet Radiation Perturbs Immune System, Makes Mice More Susceptible to Tumor Growth
• Bone Marrow Transplantation Makes High-Dose Cytoreductive Regimens, Remissions Possible
• Psychological and Social Cures Next for Children Who Recover from Cancer

Vital Signs, Winter 1985, Boonshoft School Of Medicine

Vital Signs

A twenty seven page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, alumni profiles, class notes, and more.

The Effects Of Needle Play On Pre-School Children's Anxiety Concerning Injections, Michelle Anne Belyea

Theses and Dissertations

The purpose of this study was to determine the effects of needle play in reducing pre-school children's anxiety concerning injections. The Pre-school Observational Scale of Anxiety was used to measure the degree of anxiety experienced by the children. The hypothesis stated that there would be a significant decrease in anxiety of pre-school children who participated in needle play as compared with the anxiety scores of pre-school children who did not participate in needle play.The sample consisted of 20 pre-school children who were receiving routine health care and injections for immunizations or PPDs (purified protein derivative) at a county health department …

Triage: Endgame Realities, George P. Smith Ii

Scholarly Articles

No abstract provided.

Impact Of Screening On Prognosis In The Multiple Endocrine Neoplasia Type 2 Syndromes: Natural History And Treatment Results In 105 Patients, Margareta Telenius-Berg, Bertel Berg, Bertil Hamberger, Sten Tibblin, Lars-Erik Tisell, Lars Ysander, Gunnar Welander

Henry Ford Hospital Medical Journal

We evaluated the effects of screening for multiple endocrine neoplasia type 2A (MEN-2A) in 12 families. Genealogical studies going back to 1730 show a common ancestry for seven Swedish families and one American family. The total number of patients included 105 individuals, 68 of whom were diagnosed by our screening program. Our screening methods for medullary carcinoma of the thyroid (MTC) had an optimal sensitivity and specificity. The frequency of gene carriers detected in MEN-2A families was 55%. Screening will lead to early diagnosis and early therapy, which in turn, will significantly decrease morbidity, incidence of surgical complications, and mortality …

Screening For Hereditary Medullary Cancer In Denmark, Kristian Emmertsen

Henry Ford Hospital Medical Journal

Screening of first-degree relatives of patients with medullary thyroid cancer (MTC) gave normal values of pentagastrin-stimulated serum calcitonin and 24-hour urinary catecholamine levels in the relatives of 18 of 22 patients. This result is considered to be valid evidence for sporadic MTC. Absence of C-cell hyperplasia maybe another indication of sporadic MTC. Four hereditary MTCs were represented by one fully expressed MEN-2B patient without affected relatives, one fully expressed MEN-2A case in one family, and two first cousins with MTC as the only MEN-2A lesion in another family. Fourteen relatives of the MEN-2A patients had elevated serum calcitonin levels, and …

Genetic Studies Of Multiple Endocrine Neoplasia Type 2 Syndromes: A Workshop Commentary, Nancy E. Simpson

Henry Ford Hospital Medical Journal

No abstract provided.

Digest Of The Philadelphia College Of Osteopathic Medicine (Winter 1984-1985), Philadelphia College Of Osteopathic Medicine

Digest

The Winter 1984-1985 issue of the Digest of the Philadelphia College of Osteopathic Medicine includes the following articles:

• Founders Day/ Alumni Weekend
• Portrait of a President
• Highlights of Founders Day/Alumni Weekend
• Galen S. Young, Sr., DO
• Reunions and Reminiscences
• Sherman Leis, DO
• News from the OMCP
• News from the Alumni Office
• Faculty Notes
• Alumni News Briefs
• In Memoriam
• Coming Events