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Oncolog, Volume 33, Number 01, January-March 1988, Michael J. Wargovich Phd

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• Portable Pumps and Controlled Drug Toxicity Keep More Patients Ambulatory and at Home
• Clarifications of Tumor Cell Diversification Bring New Ideas for Stopping the Process
• Chemoprevention of Colorectal Cancer

Oncolog, Volume 33, Number 03, July-September 1988, C. Stratton Hill, Jr. Md

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• Narcotics and Cancer Pain Control
• For Non-small Cell Lung Cancer, Combinations of Surgery, Chemotherapy, and Radiotherapy
• Shared Research Resources Provide Expertise and Cost Savings

Oncolog, Volume 33, Number 04, October-December 1988, Oncolog Staff

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• Neodymium: YAG Laser Therapy for Palliative Treatment of Penile Kaposi's Sarcoma
• Knowing How Normal Cells Differentiate Will Add Rationality to Stopping Cancer Cells
• New Range of Fungal Infections Seen in Cancer Patients

Oncolog, Volume 33, Number 02, April-June 1988, David M. Gershenson Md, Saroj Vadhan-Raj Md, Kathryn F. Kennedy, Wayne L. Dorris Phd

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• Epithelial Ovarian Cancer: Treatment Has Improved, But Not Enough
• The Psychosocial Impact of Cancer and the Role of Social Work
• Hematopoiesis in Myelodysplastic Syndromes Improves with Granulocyte-Macrophage Colony-Stimulating Factor

Pcom Digest Article (Winter 1988) Featuring Dr. Koch, Philadelphia College Of Osteopathic Medicine

Koch Collection, Papers of Richard S Koch, DO

PCOM Digest Article (Winter 1988) Featuring Dr. Koch, the 1988 PCOM Founder's day laureate.

Biography, Philadelphia College Of Osteopathic Medicine

Koch Collection, Papers of Richard S Koch, DO

A brief biography of Richard S. Koch, DO, FAAO, featured in PCOM's 1988 Founder's Day Program.

Richard S Koch, Do, Selected Curriculum Vitae, Philadelphia College Of Osteopathic Medicine

Koch Collection, Papers of Richard S Koch, DO

Dr. Koch's Selected Curriculum Vitae excerpted from the 1988 Founders Day Program.

Digest Of The Philadelphia College Of Osteopathic Medicine (Winter 1988), Philadelphia College Of Osteopathic Medicine

Digest

The Winter 1988 issue of the Digest of the Philadelphia College of Osteopathic Medicine includes the following articles:

• 1988 O. J. Snyder Medalist
• DOs in the Arts
• Signing Up for More Visibility
• "PCOM Couldn't Have Done it Any Better"
• Alumni Notes
• On Campus
• Class Acts
• In Memoriam
• Calendar

Clinical Use Of A Standard Kit-Preparation Of Radiolabeled Monoclonal Antibody 96.5 In The Diagnostic Imaging Of Metastatic Melanoma., Mansoor Saleh, D M. Miller, L Peterson, C D. Russell, M W. Unger

Haematology and Oncology, East Africa

We studied the efficiency of a standard-kit preparation using 1 mg 111In-labeled 96.5 monoclonal antibody in combination with 19 mg of unlabeled antibody in the diagnostic imaging of 27 patients with documented metastatic melanoma. Twenty-three of 26 patients (88%) demonstrated immunoscintigraphic localization of tumor. Of 104 metastatic sites previously documented by conventional studies, 62 (60%) were identified by immunoscintigraphy. A total of 77 sites demonstrated localization of radiolabeled antibody. Fifty-four (70%) corresponded to known sites of disease; eight sites (10%) were "discovered" by immunoscintigraphy and subsequently confirmed by conventional studies; 15 imaged sites (20%) could not be confirmed by conventional …

An Overview Of Magnetic Resonance Imaging Of The Appendicular Musculoskeletal System, Sharon C. Siegel, Allan M. Haggar, Jerry W. Froelich, Burton I. Ellis

Henry Ford Hospital Medical Journal

No abstract provided.

Pituitary Metastasis: Lung Cancer Presenting As Bitemporal Hemianopsia With Diabetes Insipidus And Anterior Pituitary Deficiency, A. Keith Cryar, Jay Morgan, Jack P. Rock, Max Wisgerhof

Henry Ford Hospital Medical Journal

Symptoms and signs of pituitary disease are rarely the first manifestations of malignancy originating in another organ. We present a case which exemplifies the key points that suggest a diagnosis of metastatic pituitary disease. Our patient's diagnosis was adenocarcinoma of the lung with a metastasis to the intrasellar and suprasellar regions, which caused diabetes insipidus, anterior pituitary deficiency, and visual field defects. The metastasis had a dumbbell appearance and extended from the sella turcica into the suprasellar region. Diabetes insipidus was the initial clinical manifestation of lung cancer in this patient. A metastasis to the pituitary should be suspected if …

Neurobehavioral Symptoms In Mild Primary Hyperparathyroidism: Related To Hypercalcemia But Not Improved By Parathyroidectomy, Gregory G. Brown, Richard C. Preisman, Michael Kleerekoper

Henry Ford Hospital Medical Journal

The neurobehavioral symptomatology of severe primary hyperparathyroidism (PHPT) has been thoroughly described. Less is known about more mild cases. We evaluated 34 patients with mild PHPT and followed 19 for an average of six months. Of those cases followed, ten had parathyroidectomy (PTX). Patients with no neurobehavioral abnormalities had the lowest serum calcium levels (10.9 ± 0.88 mg/dL), patients with signs of affective disorder had intermediate levels (11.25 ± 0.66 mg/dL), and patients with signs of cerebral dysfunction had the highest levels (12.17 ± 1.17 mg/dL). Serum calcium significantly correlated with motor speed, psychomotor speed, fluid intelligence, and short term …

Prolonged Remission Of Cushing's Disease Following Bromocriptine Therapy, Malachi J. Mckenna, Marc Linares, Raymond C. Mellinger

Henry Ford Hospital Medical Journal

A 33-year-old woman developed hypercorticism of fulminant onset following delivery of a full-term, normal child. An ectopic hormone-producing neoplasm was excluded by extensive studies. Pituitary dependent hypercorticism of intermediate lobe origin was suggested on the basis of onset following pregnancy, failure of Cortisol suppression by high-dose dexamethasone, hyperresponsiveness of prolactin to thyrotropin-releasing hormone stimulation, and reduction in adrenocorticotropin titers following oral administration of bromocriptine. Initial remission of disease achieved with bromocriptine was followed by recurrence on discontinuation of the agent. However, complete remission which occurred following a prolonged course of bromocriptine has persisted for a total of 22 months.

Report Of The Commissioner's Task Force On Self-Destructive Behaviors And Teen Suicide, Department Of Mental Health And Mental Retardation

Maine Collection

Report of the Commissioner's Task Force on Self-Destructive Behaviors and Teen Suicide.

Susan B. Parker, Commissioner - Department of Mental Health and Mental Retardation, Augusta, Maine (December 1987).

Contents: Foreward / Task Force Members / Introduction / Characteristics of Self-Destructive Teens / Factors Contributing to Self-Destructive Behaviors / Findings and Recommendations / References

Neuropsychological And Socioemotional Subtypes Of Childhood Externalizing Disorders: Cluster And Validation Analyses, Grant Jackson Butterbaugh

Dissertations

The purpose of this exploratory and confirmatory contrasted-group classification study was to determine if specifically predicted (Hypothesis 1) and externally valid (Hypotheses 3 and 4) subtypes of childhood externalizing disorders could be identified, using previously obtained neuropsychological (NP), socio-emotional (SE), and historical variables. Cross-classification validity was evaluated to determine if subjects NP and SE subtype memberships could be predicted using either their SE and NP subtype memberships or their SE and NP variable scores, respectively (Hypothesis 2). Subjects (n = 117) were 6-to-14-year-old boys and girls with normal intelligence, elevated scores on the Delinquency and/or Hyperactivity scales of the Personality …

Hypothalamic Hypogonadotropic Hypogonadism In An Adolescent Male: A Rare Manifestation Of Aqueductal Stenosis, Robert J. Wilson, Max Wisgerhof

Henry Ford Hospital Medical Journal

No abstract provided.

Effects Of Weight Reduction, Exercise, And Diet Modification On Lipids And Apolipoproteins A-L And B In Severely Obese Persons, J. David Fachnie, Craig C. Foreback

Henry Ford Hospital Medical Journal

We assessed the lipid and apolipoprotein effects of hypocaloric dieting, increased physical activity, and dietary modification in severely overweight adults (body mass index [BMI] 43.05 kg/m-). The 34 women and four men enrolled in the ambulatory weight control program donated blood before, during, and after hypocaloric dieting (420 kcal/day). Mean values before dieting included cholesterol of 223 mg/dL, high-density lipoprotein (HDL) cholesterol of 43 mg/dL, and cholesterol/HDL cholesterol of 5.90. This placed our subjects at high risk for coronary artery disease. Other values included triglycerides of 138 mg/dL, apolipoprotein A-l of 152 mg/dL. and apolipoprotein B/apolipoprotein A-l of 0.64. Significant …

Management Of Extramedullary Plasmacytomas, James A. Bonner, Jadranka Dragovic, Michael P. Abrash

Henry Ford Hospital Medical Journal

From 1965 through 1982. 12 patients with solitary, biopsy-proven extramedullary plasmacytomas (EMPs) were treated at our institution with surgery alone or biopsy followed by radiation therapy. The median age of the patients was 67 years, and the median-follow-up was 58 months. Of the seven patients who were treated by primary surgery, three developed recurrent or distant disease. Five patients underwent biopsy followed by radiation therapy, and none of their tumors progressed. Our series and a review of the literature show that occasionally EMPs will incompletely regress even after high doses of radiation (greater than 65 Gy); however, we recommend that …

Unusual Lymphomas Developing In Chronic Lymphocytic Leukemia, Sundara B. K. Raman, Sheikh M. Saeed, Joseph P. Abraham

Henry Ford Hospital Medical Journal

We report three patients with chronic lymphocytic leukemia (CLL) who developed malignant lymphomas of unusual character and modes of presentation. Two of the patients had received low doses of chlorambucil for several years before they developed malignant lymphoma, diffuse, large cell type (LCL). In one of these patients LCL manifested as a grossly evident osteolytic lesion. In the second patient LCL developed initially as a localized lesion in the iliac bone. Both patients died within a few weeks after LCL was diagnosed. The third patient, who was found to have CLL during a routine examination, did not receive any therapy …

T-Cell Lymphoma In Renal Transplant Recipient, Koichi Maeda, Leslie Bricker, Chan K. Ma, Michael J. Deegan

Henry Ford Hospital Medical Journal

A 35-year-old woman, who had a renal transplant flve years ago, developed malignant lymphoma of the mediastinum. The lymphoma was of lymphoblastic type and had T-cell immunophenotype. Most transplant-related lymphomas are of B-cell type. T-cell lymphoma in this setting is extremely rare, and the mechanism of development may be different from that of B-cell lymphomas.

Obstructing Giant Pseudopolyposis Of The Colon In Ulcerative Colitis, Roberta E. Sonnino, Farouck N. Obeid

Henry Ford Hospital Medical Journal

Pseudopolyposis of the colon is a well-recognized local complication of ulcerative colitis. Giant pseudopolyposis is uncommon, and its presentation as a complete obstruction of the colon is a rare occurrence. We report such a case, where retrograde flow of barium on double-contrast barium enema was completely obstructed at midtransverse colon. After resection by total abdominal colectomy, pathology examination ofthe specimen confirmed massive pseudopolyposis without malignancy. A brief review of the pathology and current literature is presented.

Vital Signs, December 1987, Boonshoft School Of Medicine

Vital Signs

A twelve page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, alumni profiles, class notes, and more.

Digest Of The Philadelphia College Of Osteopathic Medicine (Fall 1987), Philadelphia College Of Osteopathic Medicine

Digest

The Fall 1987 issue of the Digest of the Philadelphia College of Osteopathic Medicine includes the following articles:

• 60^th Anniversary Issue
• O. J. Snyder Medal Laureates
• PCOM Presidents
• PCOM Deans
• 1898-1913: Founders & Foundations
• 1914-1926: The Spring Garden Era
• 1927-1936: Development & Depression
• 1937-1946: The War Years
• 1947-1956: The Post-War Era
• 1957-1966: The Grandest Expansion
• 1967-1976: Progress & Exhilaration
• 1977-1987: Arrivals & New Departures
• On Campus: Faculty in Focus
• Class Acts
• Sun Coast Hospital Celebrates Its Founder & 30^th Anniversary
• In Memoriam
• Calendar

Thyroid C-Cell Hyperplasia And Micronodules In Close Relatives Of Men-2 A Patients: Pitfalls In Early Diagnosis And Reevaluation Of Criteria For Surgery, Cees J. M. Lips, John R. Leo, Marianne J. H. Berends, Werner H. Minder, A. P. Roeland Blok, Rolf A. Geerdink, Wil H. L. Hackeng, Jan M. M. Roelofs, Hans F. A. Vasen, Jan K. Vette

Henry Ford Hospital Medical Journal

In a large family with multiple endocrine neoplasia rype 2 A (MEN-2 A), 20 patients were identified by the diagnosis of medullary thyroid carcinoma (MTC) and/or pheochromocytomas. Another five subjects had neck surgery on the basis of slightly increased results of a C-cell provocative test. Retrospectively, however, although the immunohistochemical diagnosis of C-cell hyperplasia was confirmed, the diagnosis of MEN-2 was doubtful in these five subjects, and the C-cell hyperplasia observed was probably within the limits of normal variation. The occurrence of C-cell hyperplasia in a normal population was investigated by a C-cell provocative test, as well as in random …

Vital Signs, Summer 1987, Boonshoft School Of Medicine

Vital Signs

A thirty five page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, alumni profiles, class notes, and more.

Department Of Radiology-Annual Report-July 1, 1986 To June 30, 1987, David C. Levin

Department of Radiology Administrative Documents and Reports

Department of Radiology Annual Report, July 1, 1986 to June 30, 1987. Thomas Jefferson University Hospital, Philadelphia,Pennsylvania, United States. 106 pages.

One Large Kindred Excludes A Locus For Multiple Endocrine Neoplasia Type 2a From About 25% Of The Human Autosomal Genetic Map, Andrew J. Pakstis, Judith R. Kidd, Carmela M. Castiglione, Beth A. Pletcher, Patricia D. Murphy, Lindsay A. Farrer, Myron Genel, Kenneth K. Kidd

Henry Ford Hospital Medical Journal

This report presents pairwise linkage results from our search for the locus of the gene (MEN2A) for the multiple endocrine neoplasia type 2A (MEN-2A) syndrome in one large kindred (the N kindred), clearly segregating for an autosomal dominant form. About 25% of the autosomal genome is excluded when these new results are combined with those we have published previously. The genetic markers employed are distributed across at least 19 of the 22 autosomes. Seven genetic markers whose chromosomal locations are not yet established have also been studied.

Screening For Early Asymptomatic Pheochromocytoma In Men-2, Margareta Telenius-Berg, Bertel Berg, Bertil Hamberger, Sten Tibblin

Henry Ford Hospital Medical Journal

Pheochromocytoma is a major cause of morbidity in multiple endocrine neoplasia type 2. We recommend a similar diagnostic screening approach for early asymptomatic pheochromocytoma as is generally accepted for asymptomatic medullary thyroid carcinoma. We present a new provocative test for early asymptomatic pheochromocytoma. Plasma epinephrine levels and epinephrine/dopamine ratios after physical exercise seem to have higher sensitivity than basal plasma catecholamine levels. Specificity is high especially for discrimination from neurovegetative lability, which is the clinically most important differential diagnosis.

Digest Of The Philadelphia College Of Osteopathic Medicine (Summer 1987), Philadelphia College Of Osteopathic Medicine

Digest

The Summer 1987 issue of the Digest of the Philadelphia College of Osteopathic Medicine includes the following articles:

• George Hylander, DO
• The Classy '87s
• Hospital Ins & Outs
• On Campus
• Joann Cozza, DO
• Neurology Fellowship Abroad
• Class Acts
• In Memoriam
• Calendar

Digest Of The Philadelphia College Of Osteopathic Medicine (Spring 1987), Philadelphia College Of Osteopathic Medicine

Digest

The Spring 1987 issue of the Digest of the Philadelphia College of Osteopathic Medicine includes the following articles:

• Imperatives for Success
• Osteopathic's Surgicenter
• Tage N. Kvist, Ph.D.
• Research at OMCP
• The Changing Challenge of Student Recruitment
• On Campus
• PCOM's Rugby Triumph
• Class Acts
• In Memoriam
• Calendar