Digital Commons Network^™

Moraxella (Branhamella) Catarrhalis: A Molecular Epidemiology Study, Lyndell R. Gill

Electronic Theses and Dissertations

Moraxella (Branhamella) catarrhalis is the third-most-frequently isolated microorganism associated with acute exacerbations of chronic bronchitis in patients during their stay at the Mountain Home VA Medical Center (MHVAMC). In order to develop a practical, epidemiologically-meaningful typing method for M. (B.) catarrhalis, we tested two methods based on analysis of chromosomal DNA for typeability, reproducibility, and ability to differentiate between unrelated strains (discriminatory power, D). M. (B.) catarrhalis isolants from MHVAMC from 7/1/87-6/30/88 were grown overnight in broth and embedded in agarose. DNA was isolated by standard methods. The DNA was subjected to: (1) restriction endonuclease digestion (with either Bgl II …

Vital Signs, Spring 1995, Boonshoft School Of Medicine

Vital Signs

A twenty four page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, alumni profiles, class notes, and more.

Digest Of The Philadelphia College Of Osteopathic Medicine (Spring 1995), Philadelphia College Of Osteopathic Medicine

Digest

The Spring 1995 issue of the Digest of the includes the following articles:

• President's Perspective
• PCOM Leads the Way in GME
• Campaign Passes $3 Million Mark
• Memorial Service Honors Daniel L. Wisely, DO
• PCOM Profile
• Student Achievements
• PCOM Students Awarded Scholarships
• Robert S. Maurer, DO, '62: Caring for the Future
• PCOM: Never UnConventional in the Springl
• POMA Elects Officers
• PCOM Welcomes Five Board Members
• Campus Update
• Class Acts
• In Memoriam
• Coming Events
• Last Chance to Support Golf Classic Ad Book!

Mathematical Models Of Chemotherapy, John Carl Panetta

Mathematics & Statistics Theses & Dissertations

Several mathematical models are developed to describe the effects of chemotherapy on both cancerous and normal tissue. Each model is defined by either a single homogeneous equation or a system of heterogeneous equations which describe the states of the normal and/or cancer cells. Periodic terms are added to model the effects of the chemotherapy. What we obtain are regions, in parameter space (dose and period), of acceptable drug regimens.

The models take into account various aspects of chemotherapy. These include, interactions between the cancer and normal tissue, cell specific chemotherapeutic drug, the use of non-constant parameters to aid in modeling …

Ms211: Working Notes From First Trip To Kazakhstan, Armin Weinberg

Works on Radiation Effects: 1990-2020

Includes great material & notes eg, "ADW and CL returned to Semipalatinsk with BT’s car and driver. Unfortunately while returning they hit a patch of ice and ended up in a snowy ditch. Fortunately this occurred near one of the few villages along the way and a passing truck was able to pull them out. The good reflexes and driving skills of the driver kept them from overturning. ML and MR hired a car and driver from Kuchartov and returned later after completing the hospital survey" I (ADW) gave the drive $100 for pulling us out it was below zero …

Thrombolytic Therapy In Acute Myocardial Infarction In Pakistan., M. Asad Karim, Ata Ata-Ur- Rehman Qureshi, Syed Faisal Mahmood, J. Akhter

Department of Medicine

To characterize features of acute myocardial infarction (AMI) in a Pakistani population, and assess the role of thrombolysis in our country, we studied 194 consecutive admitted patients with enzyme positive AMI. Males were affected three times more frequently; women, although affected less, had a higher incidence of complications than men. Premature coronary artery disease (CAD) was present in 50% patients presenting with AMI. An unusually high incidence of anterior wall myocardial infarction (39%) was seen. Complications were frequent with a predominance of LV failure symptoms. Cardiogenic shock was associated with a very high mortality, in excess of 93%. Streptokinase (SK) …

Sustained Release Drug Delivery Devices, Thomas J. Smith, Paul Ashton, Paul A. Pearson

Ophthalmology and Visual Science Faculty Patents

A method and device for treating a mammalian organism to obtain a desired local or systemic physiological or pharmacological effect is provided. The method includes administering a sustained release drug delivery system to a mammalian organism in need of such treatment at an area wherein release of an effective agent is desired and allowing the effective agent to pass through the device in a controlled manner. The device includes an inner core or reservoir comprising the effective agent; a first coating layer, which is essentially impermeable to the passage of the effective agent; and a second coating layer, which is …

Health Professions Division Catalog 1995-1996, Nova Southeastern University

Health Professions Divisions Course Catalogs and Course Descriptions

No abstract provided.

Feasability Of Preventing Encrustation Of Urinary Catheters, J. M. Bibby, A. J. Cox, D. W. L. Hukins

Cells and Materials

Colonization of urinary catheters by bacteria which produce urease leads to an increase in urine pH, followed by deposition of the minerals struvite and hydroxyapatite. Adhesion of these encrusting deposits can be reduced, but not prevented, by using catheters with a smooth surface finish. Chemical methods for preventing encrustation are not completely satisfactory. A better way of preventing encrustation would be to prevent colonization of the catheter by bacteria. This might be achieved by controlled release of antimicrobial agents directly into the urine from the catheter itself. Preliminary experiments have demonstrated the feasibility of controlled release from solid silicone. However, …

Optical Bone Chambers As Tools For Studying The Bone-Implant Interface: A Review, Howard Winet

Cells and Materials

Bone chamber intravital microscopy combines the control volume of in vitro models and the chemical complexity of in vivo models to optimize the study of bone physiology in situ. As an optical tool it provides a window to dynamic events at the tissue level of magnification. In particular, it allows measures of microvascular events: (1) in space by magnifying local perfused vasculature and microcirculation at any instant, and (2) in time by providing the same volume of tissue for weekly viewing of an evolving process such as bone healing. This quartz-bearing titanium screw has revealed a consistent order for …

Bone Absorptiometry In Metabolic Bone Disease: Baseline Values And Long-Term Treatment With Calcitriol (Post-Menopausal Osteoporosis Versus Osteomalacia), A. Caniggia, B. Frediani

Cells and Materials

Total body bone absorptiometry reveals low mineral density in both postmenopausal osteoporosis and osteomalacia patients. The method was used to investigate the effect of calcitriol administration on patients suffering from one of these conditions. In osteomalacia, the administration of calcitriol resulted in a dramatic improvement in bone mineral density (sometimes up to 50% in 12 months), indicating the rapid mineralization of previously uncalcified bone tissue as a result of the normalization of the Ca x P product. In osteoporosis a similar treatment was seen to halt the progressive decrease in bone mineral levels and sometimes resulted in minor increases in …

Some Observations On The Structure Of Encrusting Biofilms Of Proteus Mirabilis On Urethral Catheters, C. Winters, D. J. Stickler, N. S. Howe, T. J. Williams, N. Wilkinson, C. J. Buckley

Cells and Materials

A physical model of the bladder has been used to study the process of urinary catheter encrustation. Techniques have been devised for the preparation of sections through these encrustations in situ on the luminal surfaces of catheters and for mapping the distribution of calcium and magnesium in the biofilms. Transmission electron microscopy on these sections showed struvite-like crystals lying in the matrix and in direct contact with the catheter surface. Calcium phosphate ("bioapatite") was distributed throughout the film and many of these amorphous particles appear to have cells at their cores. Freeze-substituted sections of biofilms also showed electron dense materials …

The Relationship Between Diet, Activity, And Other Factors, And Postpartum Weight Change By Race, Debra J. Boardley, Roger G. Sargent, Ann L. Coker, James R. Hussey, Patricia A. Sharpe

CRVAW Faculty Journal Articles

Objective: To identify the impact of dietary intake and activity level on postpartum weight change.

Methods: White (n = 121) and black (n = 224) women, 7-12 months postpartum, participating in the Special Supplemental Feeding Program for Women, Infants, and Children were assessed for dietary intake, activity level, body weight, and other maternal characteristics.

Results: For both black and white women, the most important variables in predicting postpartum weight loss were pre-pregnancy weight, gestational weight gain, parity, and prenatal exercise. After these factors were controlled, race predicted that black women retained 6.4 lb more than white women. These results may …

Ms211: News Clipping From 1994 Relevant To Our Interest In Chernobyl, Armin Weinberg

Works on Radiation Effects: 1990-2020

News coverage that could inform our work in Chernobyl and USA... eg, "CLINTON WEIGHS NEXT STEP ON RADIATION TESTSRTw 1/1/94 9:42 AM HILTON HEAD, SC, Jan 1 (Reuter) - President Clinton said Saturday he supports Energy Secretary Hazel O'Leary's release of documents disclosing secret Cold War radiation tests on people and said the next step is to decide what to do with the information. " See more at Armin Weinberg, PhD Papers and its finding aid.

Oncolog, Volume 40, Number 03, July-September 1995, Kathryn L. Hale, Vickie` J. Williams, Sunita Patterson

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• M. D. Anderson leads the fight against bone pain from metastatic cancer
• New computer program enhances the surgeon-patient consultation
• Bladder cancer: molecular markers may guide treatment

Oncolog, Volume 40, Number 04, October-December 1995, Kathryn L. Hale, Vickie J. Williams

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• Psychiatry at M. D. Anderson: Helping patients learn to live with cancer
• Technology and cooperation powerful tools in locating genes
• Second opinion clinic helps patients get the best treatment

Unchanged Maladies: Current Perspectives On Old Testament Diseases, Catherine A. Marco

Emergency Medicine Faculty Publications

As a physician reading the Old Testament this year, I often find myself speculating about some of the medical conditions referred to in the Old Testament. Although many disease entities have surely changed significantly over the past several thousand years, the human anatomy remains basically unchanged, thus rendering man susceptible to the same categories of disease in any day and age.

Low Income Women's Perception Of Preparedness For Self Care And Infant Care Following Discharge From A Less Than Forty-Eight Hour Hospitalization For Birth, Patricia M. Ritola

Masters Theses

The purpose of this study was to describe perceptions of preparation for self care and infant care of new mothers of low income following a short hospitalization for childbirth. Orem's nursing model was used as the conceptual framework for the study. A descriptive correlational, cross sectional design was used to examine preparedness for self care and infant care. The sample (N = 50) consisted of women who were served by Michigan Medicaid, 18 years or older and were hospitalized less than 48 hours. A telephone interview was conducted seven days after discharge.; Data were analyzed using descriptive statistics. Findings identified …

Long Term Restoration Of Peak Torque, Endurance And Muscle Activation Post Anterior Cruciate Ligament Reconstruction, Darryl Alan Turner

Theses : Honours

In recent years, Accelerated Rehabilitation (A.R.) protocols have been used following Anterior Cruciate Ligament (A.C.L.) reconstructions, the longer term effects of these programs are seldom analysed. This study examined musculoskeletal mechanisms that might affect long term functional restoration, the control subjects (n = 19) of mixed age and gender, had no previous knee deficiencies and were recreationally fit. The experimental subjects (n = 17) had undergone intra-articular A.C.L reconstruction, using bone patellar-tendon bone grafts performed by the same surgeon and had also participated in the A.R. protocol, similar to that described by Shelbourne and Nitz (1990). The experimental group attended …

Cerebral Vascular Accidents And Therapeutic Treatments, Allison L. Hartman

Presidential Scholars Theses (1990 – 2006)

A cerebral vascular accident (CVA) is commonly referred to as a stroke. Stroke is the third leading cause of death and the number one cause of serious disability in the United States. Approximately 550,000 people suffer a stroke each year; 150,000 of these result in death. Each stroke is unique. After a stroke, some victims will suffer severe deficits and/or permanent disability for the remainder of their lives. Yet other victims may suffer only mild, temporary deficits and may recover completely. Currently over three million Americans are living with the effects of stroke . Most of these individuals have been …

Loss Of The Tumor Suppressor Genes P53 And Brca1 In Prophylactic Mastectomy Cancer Patients, Garrett Griffith Losh

Presidential Scholars Theses (1990 – 2006)

More importantly, this study has shown that prophylactic mastectomy surgery is a viable and worthwhile treatment to prevent breast cancer recurrence. It is hoped that this information will increase the knowledge of breast cancer. For the same reason, this paper has attempted to explain what cancer is while describing how the genetics of a person cause or contribute to its development. Most of all, it is hoped that this paper will emphasize the severity of this disease in the United States today and tomorrow .

Patellofemoral Pain In Female Ballet Dancers: Correlation With Iliotibial Band Tightness And Tibial External Rotation, John Winslow, Evangeline Yoder

Rehabilitation Sciences Faculty Publications

Review of the literature reveals that ballet dancers have a high incidence of idiopathic patellofemoral pain. Twenty-four female ballet dancers were subjects in a study of the relationship between: 1) iliotibial band (ITB) tightness and patellofemoral pain, and 2) ITB tightness and degrees of tibial external rotation used in the dance demi-plie. Dancers were initially assessed by questionnaire to determine if any had knee pain. Twelve subjects mel the study criteria for patellofemoral pain, and 12 dancers without knee pain served as controls for the study. Iliotibial band tightness was measured (Ober test), and degrees of tibial external rotation used …

Perceptions Of Control And Satisfaction With Hospital Birth Experiences For First-Time Mothers, Clelia Tedeschi

Theses : Honours

Satisfaction with childbirth is associated with women's future emotional wellbeing. This study examined whether first- time mother's antenatal expectations, postnatal evaluations of control during labour and delivery, and the discrepancy between expectations and evaluations were significant predictors of women's satisfaction with their childbirth experiences. The effect of medical interventions (e.g., obstetrical interventions and pain relief medication) on women's perceptions of control and satisfaction was also examined. The purposive sample of eighty first-time mothers, mean age 26 years (excluding women who had caesareans) delivered at the public hospital where they attended antenatal classes. During their fourth antenatal class women completed a …

A Logistic Model Of Periodic Chemotherapy, J. C. Panetta

Mathematics & Statistics Faculty Publications

A logistic differential equation with a time-varying periodic parameter is used to model the growth of cells, in particular cancer cells, in the presences of chemotherapeutic drugs. The chemotherapeutic effects are modeled by a periodic parameter that modifies the growth rate of the cell tissue. A negative growth rate represents the detrimental effects of the drugs. A simple criterion is obtained for the behavior of the chemotherapy.

A Phenomenological Study Of Infertility : The Couple's Perspective, M. Imeson

Theses: Doctorates and Masters

The purpose of this phenomenological study was to describe and interpret the experience of infertility from the perspective of infertile couples, in order to gain an in-depth understanding of how it affects their lives. Ten to twenty per cent of the global population share the experience of infertility, however, little is known of their experiences and perceptions related to infertility. Literature to date mainly focuses on the physiological effects of infertility and does not take into account the context in which the experience takes place, or the meanings that people assign to this experience. To be effective, health carers need …

Development Of A Mammographic Image Processing Environment Using Matlab, John L. Kelley

Theses and Dissertations

Breast cancer is a disease that accounts for a disturbingly large number of deaths in females each year. Its prevalence is a topic of concern to all of us since it can affect our families, friends, and coworkers. Although mammographic screening is the most effective method currently available for the early detection of breast cancer, it is far from being an infallible procedure. Mammographic reading is error prone, partly because of the complexity of the task and partly because of the variability in human performance. Computers offer high reproducibility, and when used as an adjunct by the radiologist, may improve …

Digest Of The Philadelphia College Of Osteopathic Medicine (Fall 1994), Philadelphia College Of Osteopathic Medicine

Digest

The Fall 1994 issue of the Digest of the Philadelphia College of Osteopathic Medicine includes the following articles:

• ABC’s of Medical Education
• New Curriculum: Making Students Better Doctors
• First OMM Fellowship Recipients Named
• Herbert Lotman: Chairman of the Board
• PCOM Profile: Alexander E. Rodi, DO
• PCOM Annual Report 1994: Building for the Future
• Academic Update
• The PCOM Mission
• Master Facilities Plan
• PCOM Financial Review
• Officers of the College
• PCOM Board of Trustees
• PCOM Alumni Recognized at ACOS Convention
• PCOM Celebrates National Primary Care Day
• PCOM Golf Classic
• PCOM Appoints Senior Vice President
• Evening of Art Raises Funds for PCOM Health …

Vital Signs, Fall 1994, Boonshoft School Of Medicine

Vital Signs

A twenty page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, alumni profiles, class notes, and more.

Psychosocial Determinants Of Age-Appropriate Immunizations Of Infants In Norfolk, Virginia, Hoda Youssef Atta

Health Services Research Dissertations

This study represents an investigation of psychosocial factors affecting age-appropriate immunizations of infants in Norfolk, Virginia. A household survey was conducted in Norfolk, Virginia, from 4/93-8/93, to assess immunization coverage of children 12-30 months of age. This survey included a total of 389 children in the target age range. A subset of 201 mothers were randomly selected and reinterviewed to assess their knowledge and attitudes and the relationships of these factors to age-appropriate immunizations at 12 months of age. Sixty-two percent of children were not age-appropriately immunized at 12 months of age. Almost all mothers (99%) considered vaccines to be …

Symptoms Six Weeks After Covid-19 Are Reduced Among Us Health Care Personnel Receiving Additional Vaccine Doses During The Omicron Period, December 2021-April 2022., Nicholas M. Mohr, Ian D. Plumb, Eliezer Santos León, Malea Pinckney, Karisa K. Harland, Anusha Krishnadasan, Karin F. Hoth, Fernand Rwamwejo, John P. Haran, Melissa Briggs-Hagen, Eric Kontowicz, David A. Talan

Jefferson Hospital Staff Papers and Presentations

BACKGROUND: The objective of this study was to test the hypothesis that subsequent doses of the coronavirus disease 2019 (COVID-19) vaccine are associated with lower incidence of COVID-19-like symptoms at 6 weeks after infection.

METHODS: This study was a case-control analysis of health care personnel in an ongoing multicenter COVID-19 vaccine effectiveness study. We enrolled participants at the time of COVID-19-like symptoms between December 19, 2021, and April 27, 2022, which corresponded to the early Omicron-predominant period after original monovalent severe acute respiratory syndrome coronavirus 2 additional vaccination doses became available. Our outcome was self-reported symptoms completed 6 weeks after …