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Refractory Hypercalcemia In Sarcoidosis: Exacerbation By Thiazide Diuretics, Differentiation From Primary Hyperparathyroidism, And Possible Role Of Prolactin, A. M. Parfitt

Henry Ford Hospital Medical Journal

Hypercalcemia in a patient with sarcoidosis was made worse by a thiazide diuretic initially given to control hypercalciuria alone. The hypercalcemia was unusually resistant to corticosteroid treatment during the summer even after the thiazide diuretic had been discontinued. Lack of response to corticosteroid together with decreased tubular reabsorption of phosphate and increased tubular reabsorption of calcium suggested associated primary hyperparathyroidism, but PTH was undetectable by immunoassay, and nephrogenous cyclic AMP excretion was zero. Amenorrhea, galactorrhea and hyperprolactinemia were found to be due to a pituitary tumor which was removed. The experience with this patient suggests that: 1) exacerbation of hypercalcemia …

Effect Of Glucagon And Methylprednisolone On Pancreatectomized Recipients Of Whole Pancreas Allografts, Luis H. Toledo-Pereyra, Michael Zammit, Krishna D. Valjee

Henry Ford Hospital Medical Journal

Glucagon alone or in combination with methylprednisolone was an adequate therapeutic adjuvant for pancreatectomized recipients of whole pancreas allografts. All recipients were minimally immunosuppressed with azathioprine, 5.0 mg/K/day for three days, then 2.5 mg/K/day. The morphological, functional, and survival response after whole pancreas transplantation indicated a trend of improvement in the treated groups. Only the groups of dogs receiving glucagon alone or in combination with methylprednisolone survived more than two weeks after transplantation. This therapy has proven to be effective for whole pancreas transplantation.

Letters To The Editor

Henry Ford Hospital Medical Journal

No abstract provided.

1977 Publications Of The Staff Of Henry Ford Hospital

Henry Ford Hospital Medical Journal

No abstract provided.

Back Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Vital Signs, June, 1978,, Boonshoft School Of Medicine

Vital Signs

An eight page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, a research spotlight, alumni notes, and more.

Vital Signs, May, 1978, Boonshoft School Of Medicine

Vital Signs

An eight page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, a research spotlight, alumni notes, and more.

Vital Signs, April, 1978, Boonshoft School Of Medicine

Vital Signs

An eight page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, a research spotlight, alumni notes, and more.

Studies On Uveitis Part Ii: Hypotheses With Case Reports, Philip C. Hessburg

Henry Ford Hospital Medical Journal

A number of patients with and without uveitis are used to show that this study of aqueous microbiology suggests the following hypotheses: 1. Routine techniques currently used in most microbiology laboratories overlook classical and variant bacteria which might be isolated from clinical specimens with improved microbiological techniques. 2. Bacterial forms may be present in other ocular tissue when not present in the aqueous. 3. Polymicrobial infections probably occur rather frequently, especially in chronic or subacute inflammatory states. 4. Alterations in various host factors may subject some persons to a greater incidence of inflammatory episodes including uveitis. 5. Antibiotics used in …

Front Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Effect Of Perfusate Osmolarity On Hearts Preserved Under Hypothermic Pulsatile Perfusion For 24 Hours, Luis H. Toledo-Pereya, Manuel Chee, Richard C. Lillehei

Henry Ford Hospital Medical Journal

Canine hearts preserved under hypothermic pulsatile perfusion (24 hours) with an osmolarity of 340 mOsm/L had better preservation and transplantation response than hearts perfused at an osmolarity of 310 and 270 mOsm/L. The hearts perfused at 340 mOsm /L survived an average of 22.6 days after transplantation. This survival was significantly (p>0.05) better than that observed after fresh transplantation (13.4 days average). Hearts perfused at 270 mOsm /L had a significantly (p>0.05) lower survival after transplantation (5.8 days average) than the fresh allografts or the hearts perfused at 310 or 340 mOsm / L. Similar survival times were …

Retroperitoneal Ganglioneuroma: A Case Report And Review Of Literature, Mohammed R. Ansari, Vellore Ramakrishnan, K. S. Rajan

Henry Ford Hospital Medical Journal

Ganglioneuroma, a tumor of neural crest origin, is a rare neoplasm; to encounter it in an adult over 50 years of age is very rare. This report describes the case of a 56-year-old man who was seen at Henry Ford Hospital with an abdominal mass confirmed as ganglioneuroma on histopathology. Experience at Henry Ford Hospital and the available literature on the subject are reviewed.

The Quantitative Determination Of 3-Oxo-Bile Acids, W. T. Beher, G. J. Lin, J. Sanfield, S. Stradnieks

Henry Ford Hospital Medical Journal

A new method for the rapid quantification of 3-oxo-bile acids has been developed. From 5 to 120 μg of oxo-acid in aqueous or ethanolic media are reduced with sodium borohydride. The resulting 3α- and 3β-hydroxy acids are then oxidized in a reaction catalyzed by 3-hydroxysteroid dehydrogenase, during which nicotinamide adenine dinucleotide (NAD) is reduced to NADH. The absorbance of the reaction mixture is determined at 340 nm and is directly proportional to the amount of 3-oxo-acid in the original sample. The method is fully compatible with that used in determining 3α-hydroxy-bile acids.

Chondrosarcoma: A Report Of 65 Cases, Kent K. Wu, Edwin R. Guise, Harold M. Frost, C. Leslie Mitchell

Henry Ford Hospital Medical Journal

A statistical analysis is presented of 65 cases of chondrosarcoma treated at Henry Ford Hospital from 1916 to 1976, with adequate follow-up data.

Back Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Vital Signs, March, 1978, Boonshoft School Of Medicine

Vital Signs

An eight page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, a research spotlight, alumni notes, and more.

Vital Signs, February, 1978, Boonshoft School Of Medicine

Vital Signs

An eight page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, a research spotlight, alumni notes, and more.

Treatment Of Chlordecone (Kepone) Toxicity With Cholestyramine — Results Of A Controlled Clinical Trial, William J. Cohn , M.D., James J. Boylan , M.D., Robert V. Blanke , Ph.D., Marc W. Fariss , B.S., John R. Howell , M.S., Philip S. Guzelian , M.D.

Pathology Publications

Abstract

Industrial workers exposed to the organochlorine pesticide, chlordecone (Kepone), had signs of toxicity in several organs. The extent of toxicity was proportional to the levels of this chemical in the tissues. In 22 patients, chlordecone was eliminated slowly from blood (half time of 165±27 days — mean ± S.E.M.) and fat (half time of 125 days, with a range of 97 to 177), chiefly in the stool. Output of chlordecone in bile was 10 to 20 times greater than in stool, suggesting that chlordecone is reabsorbed in the intestine. Cholestyramine, an anion-exchange resin that binds chlordecone, increased its fecal …

Solid Tumors In Children, Harold M. Maurer , M.D.

Pediatrics Publications

No abstract provided.

Vital Signs, January, 1978, Boonshoft School Of Medicine

Vital Signs

A six page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, a research spotlight, alumni notes, and more.

The Influence Of Isotonic And Isokinetic Weight Training On Vertical Jumping Proficiency, Jeffrey Thomas Spielman

Electronic Theses and Dissertations

The purpose of this study was to determine the influence of isotonic and isokinetic weight training on vertical jumping proficiency as measured by a modified vertical jump. The subjects were college students enrolled in the Fitness and Lifetime Activities Program at South Dakota State University in Brookings, South Dakota. Isotonic and isokinetic training were assigned to the two experimental groups with the third group serving as controls. Training for the experimental groups consisted of isotonic circuit training on a Universal weight machine and isokinetic training on a Leaper machine. Data analysis included a reliability and reproducibility assessment, and a one-way …

Front Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Colonoscopic Polypectomy In A Preschool-Age Child, Carlos A. Ricotti, Bernard M. Schuman

Henry Ford Hospital Medical Journal

Colonoscopy Is a procedure used worldwide in the adult population. Here we report the case of a colonoscopic polypectomy in a preschool-age child, and we show once more that the procedure Is a safe one to perform In children if the appropriate precautions are taken.

Studies On Uveitis Part I: Aqueous Studies, Philip C. Hessburg

Henry Ford Hospital Medical Journal

Aqueous microbiological and cytological studies were performed on 134 anterior chamber taps done on 118 patients both with and without uveitis. Cell wall defective bacterial forms (CWDF) were recovered from about 40% of these aqueous specimens and classical bacteria were recovered from 12%. A statistically significant difference could not be found between the incidence of bacterial cell wall defective forms in the various anatomical types of uveitis. There were hints from this work that the presence of CWDF In the aqueous was more frequent in younger patients with uveitis, early in the uveitis attack, if there were multiple foci of …

Effect Of Steroids On Patients With Postoperative Bowel Anastomotic Dysfunction, Luis H. Toledo-Pereya, Ignacio Guzman, Earl G. Yonehiro

Henry Ford Hospital Medical Journal

Ten patients who developed anastomotic edema following large or small intestinal anastomosis had a rapid recovery after treatment with dexamethasone. The clinical and radiologic picture of adynamic ileus disappeared rapidly. There were no Immediate or long-term (more than two years) complications or side effects associated with the use of dexamethasone. This preliminary report indicates that dexamethasone may be a beneficial agent In the control of anastomotic edema.

Legionnaires' Disease: Description Of A Sporadic Case, Louis D. Saravolatz, Gene Tilchen

Henry Ford Hospital Medical Journal

This first case of Legionnaires' disease seen at Henry Ford Hospital is described. A previously healthy 72-year-old man developed progressive pneumonia in September, 1977; it was unresponsive to treatment with cephalothin. However, he rapidly recovered when the treatment was changed to oral erythromycin. Diagnosis was established by serologic studies done at the Center for Disease Control. This pneumonia occurred in a sporadic form with no evidence of secondary cases.

Long-Term Survival After Onset Of Blast Crisis In Chronic Granulocytic Leukemia: Case Report And Therapeutic Considerations, Ellis J. Van Slyck, Ahmad Samhouri

Henry Ford Hospital Medical Journal

Current analysis indicates a median survival of 3.6 months in 356 cases of chronic granulocytic leukemia after onset of blast transformation. Thirty-five (10.0%) complete remissions (CR), all of short duration, were observed. Closer scrutiny of the reported clinical experience offers clues for improving this poor outlook. A 76% CR rate can be extracted from this total experience by identifying cases treated with cytoslne arabinoside combined with one or more other agents. In isolated reports, weekly vincristine and prednisone have yielded good remission rates. Two general morphologic types of blasts can be distinguished by cytochemical stains and other features: lymphoid and …

Primary Hepatic Tumors In Women On Oral Contraceptives, V. Maciel, H. Allen, C. Grodsinsky

Henry Ford Hospital Medical Journal

Liver cell adenoma and focal nodular hyperplasia have been recognized as rare benign tumors. Their relationship with the use of oral contraceptives has been suggested since 1973. At Henry Ford Hospital, we have had four patients, ages 19, 23, 25,and 30, on oral contraceptives who presented with different clinical pictures suggesting acute abdomen. A hepatic tumor was suspected preoperatively in one patient, was found at laparotomy for biliary tract disease in two other cases, while the fourth patient presented with acute intra-abdominal hemorrhage. Hepatic resection was performed successfully in all with no mortality. The clinical presentation and diagnostic and surgical …

Vital Signs, December, 1977, Boonshoft School Of Medicine

Vital Signs

A six page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, a research spotlight, alumni notes, and more.

Vital Signs, November, 1977, Boonshoft School Of Medicine

Vital Signs

An eight page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, a research spotlight, alumni notes, and more.