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Front Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Efficacy Of Betaprone With Ultraviolet Irradiation On Hepatitis B Antigen In Human Plasma Pools (A Retrospective Study), Gerald A. Logrippo, Hajime Hayashi

Henry Ford Hospital Medical Journal

In a retrospective study, hepatitis B antigen (HB Ag) was found in 14 lots of human plasma pools (16-20 liters each) that had been treated by the combined Betaprone (BPL) with ultraviolet (UV) irradiation procedure. No evidence of clinical hepatitis was found during a six-month follow-up after 185.2 liters of HB Ag positive plasma were Infused into 257 patients. Since HB Ag positive blood products treated by BPL with UV produced no clinical hepatitis, it is evident that our treatment is efficacious against hepatitis virus agents.

Surgical Treatment Of Liver Trauma: Technical Considerations And Case Reports, C. Grodsinsky, T. A. Fox Jr., B. E. Brush

Henry Ford Hospital Medical Journal

The incidence of abdominal trauma, and thus that of liver trauma, has been increasing in the past few years. Improvements in the understanding of the anatomy of the liver and improvements in diagnostic techniques have resulted in shorter and better operations with less delay between injury and surgery. Improvements in transportation to adequate hospital facilities and vigorous resuscitative measures have also contributed to lowering the mortality rate for this type of injury. Suggestions are made for the surgical management of liver injuries, together with illustrative case reports.

Near Basal Blood Pressure: A Method Applicable To Clinical Practice, John R. Caldwell

Henry Ford Hospital Medical Journal

A method is described for determining near basal blood pressure (NBBP) measurements that is applicable to outpatient clinic or office use in daily practice. In our clinic, patients' mean casual pressure was significantly higher than the NBBP, the difference being 40 mm Hg systolic (p < .001) and 18 mm Hg diastolic (p < .001). In hospitalized patients the casual blood pressure was higher than the fourth to sixth day hospital average, and the hospital average was higher than NBBP. The difference between the last two was 15 mm Hg systolic (p <. 005) and 9 mm Hg diastolic (p < .005). In patients recording blood pressure readings at home the average weekly home-recorded blood pressure was not significantly different from NBBP during the same week, -1 mm Hg systolic (p > .80) and 4 mm Hg diastolic (p > .10). NBBP by this method offers a practical way to estimate the average daily blood pressure.

Back Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Newsletter, Volume 18, Number 05, December 1973

Newsletter: A Report to Physicians of Texas Archives

• 25th Year of Publication For The Cancer Bulletin
• Third Edition of The Book of Health Now Off Press
• New Staff
• Part of National Cancer Program Plan Presented To President Nixon
• George Elected President
• Clinical Abstracts
• Dial Access To Include 16 States, D.C.

Depression In Elderly Men Following Transurethral Prostatectom, Brenda Leach Allocco

Loma Linda University Electronic Theses, Dissertations & Projects

This study was concerned with the problem of depression among elderly patients following surgery. The purpose of the study was to find out if older men following transurethral prostatectomy experienced a higher level of depression than normal elderly people in the general population. An attempt was made in the study to suggest factors in the patients' illness or environment which may have influenced the amount of depression they experienced.

Thirty patients, sixty-five years or older, were included in the study sample. Depression was measured by a self-rating depression scale (Zung) three weeks following their operations. Other facts about the patients …

Marginal And Non-Marginal Persons In The Professions: A Comparative Study Of Recruitment In Law, Medicine, And Social Work*, Pranab Chatterjee

The Journal of Sociology & Social Welfare

A sample of students from the Schools of Law, Medicine, and Social Work of a Midwestern University (N=1,319), which consisted of all students enrolled in these schools for over a given number of years, suggests that there are at least three discernible types of marginality which are related to the status of the given professions. Such marginality may depend on one or more of the following: class origin, academic performance, and sex roles. The students of social work are high in both class- and role- marginality, but are favorably comparable to law students in performance-marginality. The study suggests that prestige …

Localization Of Deep Abscesses With Radioactive Isotopes: An Experimental Study, H. M. Allen, R. Berguer, L. A. Dusault, M. A. Block

Henry Ford Hospital Medical Journal

Life-endangering effects of deep abscesses make early and precise identification and localization important to permit adequate surgical drainage. An experiment was undertaken to study the feasibility of detecting abscesses by using leucocytes tagged with radioactive isotopes. For the labeling, 51chromium appeared preferable to 131iodine or 99technetium. Leucocytes so labelled will concentrate sufficiently in abscesses to permit identification of abscesses by scintillation scanning. For clinical application, techniques require further simplification and refinement to eliminate interference by collection of radioactive isotopes in the liver and spleen.

Statistics For Clinical Research, W. R. Mccrum

Henry Ford Hospital Medical Journal

The purpose of this paper is to make understandable the use of statistics in the field of medicine, and to introduce to the clinician some new methods of statistics for drawing some reasonable conclusions based on the meager data usually available. There is, after all, only one valid use of statistics: to enable oneself to make a personal decision based on the information available.

Publications Of The Staff Of The Henry Ford Hospital And The Edsel B. Ford Institute For Medical Research

Henry Ford Hospital Medical Journal

No abstract provided.

Front Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Primary Biliary Cirrhosis With Systemic Sclerosis, Pedro A. Diaz, Bernard M. Schuman

Henry Ford Hospital Medical Journal

Two patients with combinedbilian/ cirrhosis and scleroderma are described. Both patients also presented features of the CRST syndrome, namely Raynaud's phenomenon, and telangiectasiae. Nine previously reported cases are reviewed and the clinical data suggest that a common underlying immunologic basis may account for both clinical conditions.

A Clinical Trial Of Tobramycin With Pharmacological And Microbiological Studies, Keith Burch, Richard D. Nichols, Edward L. Quinn, Frank Cox, Evelyn J. Fisher, T. Madhavan, Donald Pohlod

Henry Ford Hospital Medical Journal

Tobramycin, a new aminoglycoside antibiotic, was shown to be effective in vitroagainst Pseudomonas, Klebsiella, Staphylococcus aureus, Enterobacter, Proteus mirabilis, indole-positive Proteus, and Eshcherichia coli. It was shown to produce serum and urine concentrations similar to gentamicin when administered intramuscularly. Preliminary animal studies showed this agent to have nephrotoxic and ototoxic effects similar to gentamicin. In our studies, tobramycin was well tolerated and produced only two transient elevations in serum creatinine and no abnormalities in audiograms and vestibular function tests. It was effective in 10 of 12 susceptible infections, including 2 of 4 with Pseudomonas endocarditis. Tobramycin compared favorably with gentamicin …

Haversian And Endosteal Bone Formation Rates In Rib Biopsies Of 50 Patients With Senile And Postmenopausal Osteoporosis, Kent K. Wu

Henry Ford Hospital Medical Journal

Eleventh rib biopsies of 50 patients with senile and postmenopausal osteoporosis, studied by means of tetracycline bone labeling, revealed significant and similar although modest decreases In bone formation on the cortical-endosteal and haversian surfaces of the biopsies.

Frank J. Sladen 1882-1973, Enisse Chimes

Henry Ford Hospital Medical Journal

No abstract provided.

Newsletter, Volume 18, Number 03, August 1973

Newsletter: A Report to Physicians of Texas Archives

• Shivers Dedicates Rehab Annex
• Immunological Aspects of Neoplasia Spotlighted at 26th Annual Symposium
• Summer Science Students Report Research
• Dr. Derrick Receives Award
• Blumenschein Named Assistant Director
• Anderson breaks Ground for Hospital
• 18th Clinical Conference Set for November 8-10 – Diagnosis Emphasized
• New Staff

Oral History Interview: Dr. Don V. Hatton And Jane Hatton, Don V. Hatton, Jane Hatton

0064: Marshall University Oral History Collection

Dr. Don V. Hatton was a physician and public health specialist in both West Virginia and Kentucky beginning in the 1930s. During his interview, Dr. Hatton discusses Appalachia and focuses on the definition of the region and what it means to be Appalachian. He also discusses his transition from being a public health specialist focused on preventative medicine to a practicing internal medicine physician. In the audio clip provided, he compares and contrasts his public health work in West Virginia and Kentucky through a focus on physical environment, education, and socioeconomic status. Throughout this interview, Dr. Hatton’s wife, Jane Hatton, …

Back Matter

Henry Ford Hospital Medical Journal

No abstract provided.

Complications Of Treated Cushing's Syndrome, Lewis B. Morrow, Raymond C. Mellinger, M. Saeed Zafar, Richmond W. Smith Jr.

Henry Ford Hospital Medical Journal

Fifty-two patients with Cushing's syndrome are reported with emphasis on post treatment complications. Seven patients, cured of their disease following appropriate therapy, had a recurrence of adrenal hypersecretion from one to ten years later. This occurred after all modalities of treatment, but was more common after sub-total adrenalectomy. Pituitary adenomas were found in two cases. Pseudotumor cerebri, psychiatnc complications, hyperthyroidism and hyperpigmentation were observed. One patient developed progressive hyperplgmentation despite pituitary radiation. Thirteen of fifty-two patients had malignant disease including three endometrial carcinomas, one rectal carcinoma and one adenocarcinoma of the mandible. Despite the remarkable improvement In the prognosis for …

Toxic Megacolon In Granulomatous Colitis, K. Anselm, S. A. Rosenblum, V. De Marco

Henry Ford Hospital Medical Journal

Acute, toxic dilatation of the colon in granulomatous colitis occurs more frequently than heretofore reported, and is a more serious complication than its counterpart in ulcerative colitis. Twenty-six patients who had toxic megacolon were seen at the Henry Ford Hospital between 1961 and 1971. Fourteen of these had ulcerative colitis and 12 had granulomatous colitis. Coricosteroids were relatively ineffective in these 12 patients and all but two needed surgical intervention. Postoperative complications occurred in two cases, with two deaths. Although the initial clinical picture between the two conditions is identical, the clinical course In those with granulomatous colitis is more …

The Scanning Electron Microscope: Applications At The Edsel B. Ford Institute For Medical Research, John H. L. Watson

Henry Ford Hospital Medical Journal

The Henry Ford Hospital with its research partner, The Edsel B. Ford Institute for Medical Research, was the first private medical center in the State of Michigan to purchase a scanning electron microscope and to begin to apply it, a year ago, to the study of medical and biological problems in both the animal and the human. This article briefly describes how the instrument works and shows some samples of micrographs produced.

Front Matter

Henry Ford Hospital Medical Journal

No abstract provided.

The Involvement Of Urinary Kallikrein In The Renal Escape From The Sodium Retaining Effect Of Mineralocorticoids, M. Marin-Grez, N. B. Oza, Oscar A. Carretero

Henry Ford Hospital Medical Journal

It is well known that the normal kidney "escapes" the sodium retaining effect of mineralocorticoids. However, the mechanism that mediates this "escape" is not understood. The possible role of kallikrein in this "escape" phenomenon was investigated by placing seven dogs in metabolic cages and giving them a constant sodium diet. After they had been on this diet three days, urine was collected for two 24-hour periods. DOCA (25 mg/day) was then given intramuscularly for five days. Urine was collected daily during this DOCA period and for two additional 24- hour periods. Urine volume, sodium, potassium, protein, and kallikrein excretion were …

Experience With Cleft Lip And Palate At The Henry Ford Hospital, W. Peter Mccabe

Henry Ford Hospital Medical Journal

A detailed analysis is presented of 321 patients with clefts of the lip and/or palate treated at Henry Ford Hospital. Comments are made on past and future trends in the management of these complex entities.

Publications Of The Staff Of The Henry Ford Hospital And The Edsel B. Ford Institute For Medical Research

Henry Ford Hospital Medical Journal

No abstract provided.

Digest Of The Philadelphia College Of Osteopathic Medicine (Summer 1973), Philadelphia College Of Osteopathic Medicine

Digest

The Summer 1973 issue of the Digest of the Philadelphia College of Osteopathic Medicine includes the following articles:

• Commencement
• Dedication, Evans Hall
• Reunion Festivities
• Reunion Photos
• Professional Programs
• Alumni Association Meeting
• Commencement Dinner
• Student Awards
• College News
• People
• Progress Briefs
• News from the Hospital and Clinics
• Faculty Notes
• Faculty Promotions
• Alumni News Briefs
• Class of 1973
• In Memoriam

Cephalometrics For The Oral Surgeon In The Diagnosis Of Facial Deformities, Frederick J. Mantz

Loma Linda University Electronic Theses, Dissertations & Projects

Surgical orthodontics presents a challenge to the oral surgeon. By the nature of the oral surgeon's training and discipline he should be the one best qualified to treat the surgical aspect of the surgical orthodontic case. The establishment of a proper diagnosis and means of communication between the oral surgeon and orthodontist are essential in achieving a good final result for the surgically treated case. Fortunately, a scientific method of diagnosis is available that can provide both specialties with a common language. Computerized cephalometric analysis can provide the diagnosis and link of communication for the discussion of goals and treatment. …

A Method Of Analyzing Mandibular Movement, Richard B. Mccoy

Loma Linda University Electronic Theses, Dissertations & Projects

Mandibular movement is considered to be a fundamental factor in the study, analysis, and treatment of occlusion. For many years, dentists have realized that dental health depends upon the compatibility of mandibular movements and occlusion. This realization has led to the development of new methods and techniques for recording accurately and scientifically the movements of the mandible. In order for this data to be of scientific value, it must be stored in a usable form which is easily available for analysis.

The purpose of this research project was to develop a procedure for storing and recalling mandibular-movement information. Before such …

Role Of Membrane-Associated Components Of Mycoplasma Arthritidis On The Biosynthesis Of Humoral Antibodies And Arthritogenic Properties In Experimental Animals, Lois M. Bergquist

Loma Linda University Electronic Theses, Dissertations & Projects

The virulence of animal-passaged Mycoplasma arthritidis (158) was demonstrated to be enhanced in rats by growth in oleic acid-enriched broth. The virulence of a laboratory-maintained culture of the same strain was unaffected by similar growth conditions. No differences either in the immune response as measured by complement-fixing (CF) antibodies or in the histogenesis of the disease were detected when rats were injected with animal-passaged M. arthritidis grown either in the presence or in the absence of oleic acid. All tests for metabolism-inhibiting (MI) antibodies in the rat were negative.

A Mycoplasma-associated immunosuppression of the primary and of the secondary hemagglutinin …