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Oncolog, Volume 44, Number 12, December 1999, Margaret E. Goode, Dawn Chalaire, John Mendelsohn Md

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• Collaboration Between Scientists, Clinicians Moves Apoptosis Studies Forward
• Answering the Who, What, and How of Medical Physics
• USHERING IN NEW TECHNOLOGIES: Medical Physicists Focus on IMRT, Ultrasound-Guided Brachytherapy
• DiaLog: Building Better Patient Care on the Foundation of Scientific Research, by John Mendelsohn, MD, President, Professor of Clinical Investigation
• House Call: Make Cancer Prevention Part of Your New Year's Resolutions

Self-Reported Feeding Advice By Physicians For Common Childhood Illnesses, S Q. Nizami, Z A. Bhutta

Department of Paediatrics and Child Health

Background: A nutritious diet is important for recovery during illnesses. Dietary advice by physicians and consumption of food by the patients are often based upon their hot and cold concepts and beliefs about various foods rather than on scientific basis.
Objectives: To look at the food-advising behaviour of physicians during illnesses and to know the maternal concepts about various foods being hot or cold.
Methods: A questionnaire was served to the physicians participating in a continuous medical education session held at the Aga Khan University and Hospital, asking them to write the foods they advise or restrict during different illnesses …

Oncolog, Volume 44, Number 11, November 1999, Beth Notzon, Dawn Chalaire, Rhonda L. Moore Phd

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• Overcoming Side Effects: Department of Internal Medicine Specialties Finds Ways to Continue Critical Treatments
• Partners in Knowledge, News in Cancer: P.I.K.N.I.C. Program Brings Physicians, Patients Together
• House Call: CIS: Answering the Call for Help
• Advances in Control of Nausea, Vomiting Aim to Reduce 'Misery Quotient'
• DiaLog: Finding Meaning in Stories of Pain and Suffering, by Rhonda L. Moore, PhD, Postdoctoral Fellow, Department of Epidemiology
• Protocols: Side Effects of Cancer and Cancer Treatments Are the Subject of Clinical Investigations

Oncolog, Volume 44, Number 10, October 1999, Dawn Chalaire, Alison Ruffin, Vickie J. Williams

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• Stereotadic Unit Expands Treatment Options for Patients with Brain Tumors
• New Center Teams With Community Physicians to Treat Patients With Advanced Cancer
• IRS Deduction Gives Smokers One More Reason to Quit
• Accuracy Essential in Stereotactic Radiosurgery
• House Call: Vitamins and Cancer Risk: Why You Should Eat Your (Fruits and) Vegetables
• Protocols: Brain Tumor Protocols Include Stereotactic Treatments, Surgery, and Radiation Therapy

Postprandial Glucose Response To Mango, Banana And Sapota, Z Contractor, F Hussain, A Jabbar

Section of Pulmonary & Critical Care

Objective: Mango and Sapota are two fruits indigenous to Indian subcontinent. The objective of this study was to evaluate postprandial blood glucose response to mango and sapota in comparison to banana in patients with diabetes mellitus Type 2.METHOD: The plasma glucose response to mango, sapota and banana were determined in ten diabetic patients. Blood was tested at 0, 30, 60, 120 and 180 minutes following the ingestion of test meal.Results: The results showed that the blood glucose response to these three fruits was not different in terms of area under the curve and postprandial change in blood glucose from baseline.CONCLUSION: …

Oncolog, Volume 44, Number 09, September 1999, Dawn Chalaire, Alison Ruffin, Vickie J. Williams, Aman Buzdar Md

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• Cautious Approach to Soft Tissue Sarcoma Yields More Favorable Outcomes
• What's to Eat? Encouraging children to eat well for a healthier future
• Orthopaedic Surgeons Save Limbs, Restore Function for Patients with Bone Tumors
• DiaLog: High-Dose Chemotherapy Deserves More Study, by Aman Buzdar, MD, Professor, Department of Breast Medical Oncology
• House Call: Breast Cancer: Understanding the Risks
• Protocols: Sarcoma/Osteosarcoma Clinical Trials

Spectrum Of Hodgkin's Disease In Children And Adults: Impact Of Combined Morphologic And Phenotypic Approach For Exclusion Of Look-Alikes, Tanya Siddiqui, Shahid Pervez

Department of Pathology and Laboratory Medicine

Objective:

To determine the prevalence of Hodgkin’s disease (HD) and its various subtypes in children and adults and assess the use of immunohistochemical (IHC) studies in confirming HD cases and excluding its close mimicries/look-alikes.

Material and Methods:

All 265 Hodgkin’s disease cases diagnosed at The Aga Khan University Hospital, Karachi over the last 6 years (July 1991 - July 1997) were included. Of these 219 were diagnosed on routine H&E examination while in the remaining 46 cases, diagnosis was made after a thorough IHC workup. (This group initially included 161 cases labelled as lymphoproliferative disorder with HD as one of …

Dietary Practices And Beliefs Of Patients With Chronic Liver Disease, S H. Badruddin, S M. Jafri, A Ahmed, S Abid

Section of Diabetes, Endocrinology and Metabolism

Objective: To study of the dietary practices and beliefs of patients suffering from chronic liver disease.

Setting: Two private tertcary care hospitals.

Method: Fifty patients presenting to the Gastroenterology Clinics at the Aga Khan University Hospital and Baqai Hospital, with compensated liver disease and no other co-morbid condition which required dietary modifications, were enrolled in the study. Patients were interviewed regarding their current dietary practices using an open-ended questionnaire.

Results: The mean age of the patients was 48 years and the majority were in relatively poor nutritional status. Four had BMI's < 18; 58% had Hb < 12 g/dl and 36% had albumin levels < 3 gm/dl. The percentage of patients avoiding various foods is as follows: meats 72%, fats and oils 64%, salt 42%, spices 34%, milk and milk products 28%, rice 20%.

Conclusion: The most commonly cited reason for avoiding a …

Global Cns Gene Transfer For A Childhood Neurogenetic Enzyme Deficiency: Canavan Disease., Paola Leone, Christopher G Janson, Scott J Mcphee, Matthew J During

Department of Neurosurgery Faculty Papers

The neurogenetic prototypic disease on which we chose to test our gene therapy strategy is Canavan disease (CD). CD is an autosomal recessive leukodystrophy associated with spongiform degeneration of the brain. At present the disease is uniformly fatal in affected probands. CD is characterized by mutations in the aspartoacylase (ASPA) gene, resulting in loss of enzyme activity. In this review, recent evidence is summarized on the etiology and possible treatments for CD. In particular, we discuss two gene delivery systems representing recent advances in both viral and liposome technology: a novel cationic liposome-polymer-DNA (LPD) complex, DCChol/DOPE-protamine, as well as recombinant …

Factors Which Affect Post-Hospital Resource Use And Patient Health Outcomes Among Taiwanese Older Adults, Chouh-Jiaun Lin

Health Services Research Dissertations

The purpose of this study was to explore relationships among population characteristics, patient post-hospital resource use and patient health outcomes in terms of the Andersen health behavioral model. An additional purpose of this study was to examine a discharge planning screening instrument used in a large urban hospital in Taiwan to determine if it predicts resource use and patient outcomes. A longitudinal research design was adopted for this study. Data were collected from the general medicine departments of an 800-bed university teaching hospital. Out of 109 patients who were interviewed, 78 participants qualified (participation rate = 71.6%).

The majority of …

Identification And Characterization Of Determinants Of Head And Neck Tumor Cell Invasion, Yangguan Wu

Theses and Dissertations in Biomedical Sciences

Head and neck squamous cell carcinoma (HNSCC) is a common malignant disease with poor prognosis. The majority of patients die from local invasion or lymphatic metastasis. The mechanism(s) underlining the invasiveness of HNSCC are poorly understood. Utilizing a panel of HNSCC cell lines previously established in our laboratory, we tested the application and relevance of the three-step hypothesis of tumor invasion to HNSCC and investigated the mechanism(s) pertaining to the regulation of each step in the invasive process. Data presented in this thesis demonstrated that tumor cell invasion in HNSCC is a complex process involving three repeated sequential steps: adhesion, …

Oncolog, Volume 44, Number 06, June 1999, Jude Richard, Michael Courtney, Alison Ruffin, Dawn Chalaire

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• After Diagnosis, Another Hurdle: Cancer Screening for the Cancer Patient
• House Call: Reduce Cancer Risk With Regular Cancer Screening
• M. D. Anderson Participates in Multinational Breast Cancer Prevention Trial of Tamoxifen and Raloxifene
• Nerve Grafting Attempts to Restore Erectile Function After Prostatectomy
• M. D. Anderson Researchers Study Children's School Lunch Habits and Choices

Dysphagia In Hereditary Sensory Autonomic Neuropathy Type Iv, U Shah, M Arshad, T Mozaffar

Department of Paediatrics and Child Health

No abstract provided.

Oncolog, Volume 44, Number 02, February 1999, Nancy Arora, Sunni Hosemann, Kimberly Jt Herrick

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• Laryngeal Mask Airway: A New Frontier in Airway Management
• House Call: Exercise--A Hop, Skip, and a Jump for Reducing Cancer Risk
• Conferences Offer Variety of Topics
• Cervical Cancer Study Results Expected to Change Practice
• May I Take Your Order?

Filling The Geriatric Gap: Is The Health System Prepared For An Aging Population?, Janet Firshein

National Health Policy Forum

This issue brief explores the field of geriatrics, the ways practitioners meet the health care needs of the elderly, training gaps, and the impact of Medicare payment policies on the delivery of health care to older Americans.

Geriatric Interdisciplinary Team Training, Rita Jablonski, David A. Cifu, Peter A. Boling, Patricia Slattum, A. Leigh Peyton, F. Ellen Netting, Iris A. Parham, Joan B. Wood

Case Studies from Age in Action

Educational Objectives

1. To demonstrate the importance of training health care professionals in inter-disciplinary teamwork and geriatric health issues.

2. To increase one’s knowledge of the roles and responsibilities of the various disciplines involved in interdisciplinary teamwork.

Vital Signs, Winter 1999, Boonshoft School Of Medicine

Vital Signs

A twenty four page newsletter created by the Boonshoft School of Medicine to document the current affairs of the school. This issue includes a variety of feature articles, alumni profiles, class notes, and more.

Oncolog, Volume 44, Number 01, January 1999, Stephanie Deming, Lewis Foxhall M.D., Sunni Hosemann, Beth W. Allen

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• Innovative PET Camera Readied for Tumor Detection Trials
• House Call: How to Talk With Your Doctor
• Community Physicians: Important Partners With M. D. Anderson
• DiaLog: Liaison Program Strives to Enhance Access, by Lewis Foxhall, MD, Associate Vice President for Health Policy
• Fatigue: The Multidimensional Side Effect
• High Resolution, High Sensitivity, and Variable Field of View Set MDACAM Apart

The Tostan Story: Breakthrough In Senegal Ending Female Genital Cutting, Population Council

Reproductive Health

In Senegal, elements of the Tostan education program were fundamental to the ending of the practice of female genital cutting (FGC) which has persisted for centuries, despite outside efforts to abolish such a dangerous and harmful operation. This paper is an attempt by those who lived through these events to share the experience with others. At a time when there has been little reduction in the numbers of women ending FGC in 28 African countries, when different programs and strategies have rarely succeeded in making an impact on the number of women still practicing FGC despite laws abolishing the tradition, …

Effect Of Prepregnancy Body Mass Index And Gestational Weight Gain On Birth Weight, S S. Merchant, I A. Momin, A A. Sewani, N F. Zuberi

Department of Obstetrics & Gynaecology

Objective: Nutritional status of women has been considered an important prognostic indicator of birth outcome. The study aims to show the effect of various prepregnancy Body Mass Index (BMI) categories and corresponding gestational weight gain on newborn birth weight.
Methods: Two hundred women were included in the study. These women had regular antenatal visits and later delivered at The Aga Khan University Hospital (AKUH) between the period January 1, 1996 to December 31, 1997.
Results: For women with prepregnancy BMI < 19., mean birth weight of newborns was lower for those gaining < 12.5 kg than those gaining > 12.5 kg (P < 0.001). Women who started their pregnancy with BMI 19.8-26 and gained weight above expected range gave birth to high birth weight babies (P = 0.009). Gestational weight gain did not have a significant association with birth weight for women having prepregnancy BMI > 26.
Conclusion: Efforts should be made to attain adequate prepregnancy weight to reduce the likelihood of low …

The Association Of Fluid Intake With Total Natural-Cause Mortality, Coronary Heart Disease And Fatal Stroke, Jacqueline Chung Lun Chan

Loma Linda University Electronic Theses, Dissertations & Projects

Hypohydration may be more widespread than realized since it does not always arouse a sense of thirst. When thirst is felt, it is often ignored, or satisfied before euhydration is achieved. There is growing evidence indicating that hypohydration contributes to acute and chronic illnesses, and to rheological factors associated with coronary heart disease (CHD) and stroke. Therefore the relationship of fluid intake with risk of total natural-cause mortality, CHD and stroke death was examined using data on 34,192 white, non-Hispanic participants in the Adventist Health Study.

Among the 27,342 reporting no CHD, stroke or diabetes at baseline, during six years …

Native Outreach: A Report To American Indian, Alaska Native And Native Hawaiian Communities, C.S. Glover, F.S. Hodge

Native Health Database Full Text

The National Cancer Institute (NCI) is presenting a monograph written specifically for community leaders, health professionals and lay health workers serving Native American communities. Native Americans have higher mortality rates than the general U.S. population for several major cancer sites. This publication focuses on the need to reduce those rates through effective interventions at the grassroots level.

The Efficacy Of A Developmental Follow-Up Program For High-Risk Infants, Laurie M. De Jong

Graduate Student Dissertations, Theses, Capstones, and Portfolios

Objective: To assess the efficacy of a developmental follow-up program provided at a local community hospital. Efficacy was measured by the number of children referred to early intervention services and the cost effectiveness of the program. Design: This is a retrospective study of 174 children evaluated during 272 visits in the Follow-up Clinic from the inception of the program on November 22, 1994 through December 31, 1998. The data collected included referral rates and demographic information on all children. Financial information was also obtained on 74 children seen during a one year period to assess the financial implications of the …

Poor Performance Of Health And Population Welfare Programmes In Sindh: Case Studies In Governance Failure, Mehtab S. Karim, Shehla Zaidi

Community Health Sciences

Over the past few years, the issue of what is meant by “good governance” has generated increasing attention and debate both at the national and international level [Streeten (1997)]. The role of state and how that role is to be exercised is appearing high on the agenda of politicians, policy-makers and academicians in the developing world. Governance has been defined by the World Bank as “the manner in which power is exercised in the management of the country’s economic and social resources” [World Bank (1994)]. The somewhat narrow scope of this definition has been broadened in recent years to “the …

Myelofibrosis In Severe Vitamin D Deficiency Rickets, Mehnaz Atiq, Zehra Fadoo, Fouzia Naz, Mohammad Khurshid

Department of Paediatrics and Child Health

Vitamin D deficiency is prevalent in infants and children in the underdeveloped countries¹. Infants with mild deficiency tend to present with complications like hypocalcemic seizures whereas occurrence of pathological features in advanced rickets is well elucidated². Secondary myeloflbrosis has been reported as a complication of severe rickets and in these children anemia, myeloid metaplasia and bone marrow aplasia strongly suggested myelofibrosis. Despite the high prevalence of rickets in the Indo-Pakistan subcontinent, there has been no report on this complication.We present a case of severe clinical rickets who had developed secondary myelofibrosis with hepatosplenomegaly. The purpose of …

A Cross-Sectional Study Examining Lifestyle And Rheumatoid Arthritis, Leslie Nazaroff

Loma Linda University Electronic Theses, Dissertations & Projects

Objective. Rheumatoid arthritis (RA) is a chronic inflammatory disease that affects the synovial joints. RA affects 0.5-2% of the population. Though it is predominantly a progressive disease, adjunct therapy may slow the destructive pathway or alleviate affiliated symptoms. This study examined the effects of lifestyle (diet and exercise) and self-efficacy on symptoms of RA as measured by disease activity and health satisfaction.

Methods. Seventy-five RA patients (77% female) from the Loma Linda University Faculty Medical Offices, Rheumatology Department completed self-assessment surveys on their lifestyle practices and RA affliction. Disease symptoms and activity were assessed with the Arthritis Impact Measurement …

Oncolog, Volume 43, Number 08, August 1998, Don Norwood, David Bababian, Beth W. Allen, Allison Ruffin, Stephen P. Tomasovic Phd

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• Non-Hodgkin's lymphoma therapy innovations improve patient response
• Tamoxifen helps women escape breast cancer's shadow
• Careful inspection, early detection important in controlling oral cancer
• Protocols: Non-Hodgkin’s Lymphoma Protocols Feature Chemotherapy, Radiotherapy, and Monoclonal Antibodies
• House Call: Americans’ Appetite for Alternative Medicine: Is It a Safe Diet?
• DiaLog: Comprehensive in More Ways than One, by Stephen P. Tomosovic, PhD, Associate Vice President for Educational Programs

Leukemia Inhibitory Factor (Lif): Murine Preimplantation Embryo Development, Implantation Rates, And Skeletal Development, Michael Hayes Mitchell

Theses and Dissertations in Biomedical Sciences

Leukemia inhibitory factor (LIF) is a pleiotropic cytokine which demonstrates perplexing physiological effects. It has been demonstrated that LIF is essential for implantation in mice. Little is known relating to the manner by which LIF effects pre-implantation and post-implantation development. The objectives of this project were to determine the effects LIF on pre-implantation development, to determine the effects that it may have on implantation rates, successful pregnancy rates, and resorption rates, and to determine the effects that LIF has on the skeletal development of mice. For the embryo transfer experiments, embryos were exposed to test compounds in the transfer medium …

Health Risk Behaviors Among Maine Youth : Results Of The 1997 Youth Risk Behavior Survey, Grades 7-12, Chuck Rhoades

Maine Collection

Health Risk Behaviors Among Maine Youth : Results of the 1997 Youth Risk Behavior Survey, Grades 7-12

Prepared for the Maine Department of Education by Chuck Rhoades of CERES Associates, Inc., Survey Administered by Pan Atlantic Consultants / Strategic Marketing Services (June, 1998).

Contents: Introduction / Methodology / Demographics / Safety, Violence & Suicide / Alcohol, Drug & Tobacco Use / Sexual Behaviors / Health Care, Physical Activity & Nutrition / References

The Relation Of Weight Loss And Improved Fitness To Survival In Healthy Males, Joanna Lynn Bokovoy

Loma Linda University Electronic Theses, Dissertations & Projects

Obesity is a critical public health problem because of its prevalence, medical and psychosocial effects, and resistance to intervention. Weight loss in overweight individuals has been encouraged by the United States Public Health Service and by the medical community as a means for improving health. However, recent studies have suggested either positive or negative effects of weight loss on survival. It is possible that physical fitness may have a confounding effect, or be an effect modifier on survival in weight loss studies.

This study used Cox Regression analysis to address the separate and combined association of weight loss and improved …