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Predictors Of Hyperkalemia And Outcomes Of Dyskalemia In Us Veterans With Advanced Chronic Kidney Disease Transitioning To Dialysis, Ankur Dashputre Apr 2022

Predictors Of Hyperkalemia And Outcomes Of Dyskalemia In Us Veterans With Advanced Chronic Kidney Disease Transitioning To Dialysis, Ankur Dashputre

Theses and Dissertations (ETD)

Background: The kidneys play a crucial role in maintaining homeostasis of serum potassium levels (K+). Patients with advanced chronic kidney disease (CKD) are at a higher risk of experiencing dyskalemia events (i.e. hyper- and hypokalemia; especially the former) and thus future adverse outcomes. Currently, there is a dearth of literature on prediction models for hyperkalemia and the effects of dyskalemia on outcomes such as incidence of ischemic stroke and short-term hospital/emergency room (ER) utilization in an advanced CKD population transitioning to dialysis. Objectives: Using a nationally representative sample of US veterans with advanced CKD transitioning to dialysis, in the pre-dialysis …


Targeting Calcium-Mediated Inter-Organellar Crosstalk In Cardiac Diseases, Mohit M Hulsurkar, Satadru K Lahiri, Jason Karch, Meng C Wang, Xander H T Wehrens Apr 2022

Targeting Calcium-Mediated Inter-Organellar Crosstalk In Cardiac Diseases, Mohit M Hulsurkar, Satadru K Lahiri, Jason Karch, Meng C Wang, Xander H T Wehrens

Faculty, Staff and Students Publications

INTRODUCTION: Abnormal calcium signaling between organelles such as the sarcoplasmic reticulum (SR), mitochondria and lysosomes is a key feature of heart diseases. Calcium serves as a secondary messenger mediating inter-organellar crosstalk, essential for maintaining the cardiomyocyte function.

AREAS COVERED: This article examines the available literature related to calcium channels and transporters involved in inter-organellar calcium signaling. The SR calcium-release channels ryanodine receptor type-2 (RyR2) and inositol 1,4,5-trisphosphate receptor (IP

EXPERT OPINION: Enhanced SR calcium release via RyR2 and reduced SR reuptake via SERCA2a, increased VDAC and MCUC-mediated calcium uptake into mitochondria, and enhanced lysosomal calcium-release via lysosomal TPC and TRPML …


Risk Factors Associated With Patient-Reported Fatigue Among Long-Term Oropharyngeal Carcinoma Survivors, Puja Aggarwal, Katherine A Hutcheson, Ryan P Goepfert, Adam S Garden, Naveen Garg, Frank E Mott, Clifton D Fuller, Stephen Y Lai, Gary Brandon Gunn, Mark S Chambers, Ehab Y Hanna, Erich M Sturgis, Sanjay Shete Apr 2022

Risk Factors Associated With Patient-Reported Fatigue Among Long-Term Oropharyngeal Carcinoma Survivors, Puja Aggarwal, Katherine A Hutcheson, Ryan P Goepfert, Adam S Garden, Naveen Garg, Frank E Mott, Clifton D Fuller, Stephen Y Lai, Gary Brandon Gunn, Mark S Chambers, Ehab Y Hanna, Erich M Sturgis, Sanjay Shete

Faculty, Staff and Students Publications

BACKGROUND: The study objective is to identify risk factors associated with fatigue among long-term OPC survivors.

METHODS: This cross-sectional study included disease-free OPC survivors treated curatively between 2000 and 2013 who were surveyed from September 2015 to July 2016. The outcome variable was patient-reported fatigue. Multivariable logistic regression was used to identify factors associated with moderate to severe fatigue.

RESULTS: Among 863 OPC survivors, 17.4% reported moderate to severe fatigue. Self-reported thyroid problems (OR: 2.01; p = 0.003), current cigarette smoking at time of survey (OR: 3.85; p = 0.001), late lower cranial neuropathy (OR: 3.44; p = 0.002), and …


Peppermint Oil Effects On The Gut Microbiome In Children With Functional Abdominal Pain, Santosh Thapa, Ruth Ann Luna, Bruno P Chumpitazi, Numan Oezguen, Susan M Abdel-Rahman, Uttam Garg, Salma Musaad, James Versalovic, Gregory L Kearns, Robert J Shulman Apr 2022

Peppermint Oil Effects On The Gut Microbiome In Children With Functional Abdominal Pain, Santosh Thapa, Ruth Ann Luna, Bruno P Chumpitazi, Numan Oezguen, Susan M Abdel-Rahman, Uttam Garg, Salma Musaad, James Versalovic, Gregory L Kearns, Robert J Shulman

Faculty, Staff and Students Publications

Peppermint oil (PMO) is effective in the treatment of functional abdominal pain disorders, but its mechanism of action is unclear. Evidence suggests PMO has microbicidal activity. We investigated the effect of three different doses of PMO on gut microbiome composition. Thirty children (7-12 years of age) with functional abdominal pain provided a baseline stool sample prior to randomization to 180, 360, or 540 mg of enteric coated PMO (10 participants per dose). They took their respective dose of PMO (180 mg once, 180 mg twice, or 180 mg thrice daily) for 1 week, after which the stool collection was repeated. …


A Multi-Disciplinary Approach To Chronic Cough In Children, Shraddha S Mukerji, Naga Jaya Smitha Yenduri, Eric Chiou, Siby P Moonnumakal, Joshua R Bedwell Apr 2022

A Multi-Disciplinary Approach To Chronic Cough In Children, Shraddha S Mukerji, Naga Jaya Smitha Yenduri, Eric Chiou, Siby P Moonnumakal, Joshua R Bedwell

Faculty, Staff and Students Publications

OBJECTIVES: (1) To highlight the important causes of chronic and recurrent cough in children. (2) To discuss multidisciplinary approach to management of chronic/recurrent pediatric cough.

METHODS: Review of scholarly articles, guidelines, expert panels via PubMed and Google Scholar.

CONCLUSION: Chronic cough (CC) in children is mainly attributed to persistent bacterial bronchitis, asthma, nonspecific cough, and gastroesophageal reflux disease (GERD) symptoms. A multi-disciplinary approach is cost-effective and aids with earlier diagnosis and appropriate treatment. Congenital or acquired narrowing of the subglottis is the leading ENT cause for recurrent croup (RC) in children. Laryngeal cleft-type 1 is commonly seen in children with …


Vestibular Rehabilitation For Peripheral Vestibular Hypofunction: An Updated Clinical Practice Guideline From The Academy Of Neurologic Physical Therapy Of The American Physical Therapy Association, Courtney D Hall, Susan J Herdman, Susan L Whitney, Eric R Anson, Wendy J Carender, Carrie W Hoppes, Stephen P Cass, Jennifer B Christy, Helen S Cohen, Terry D Fife, Joseph M Furman, Neil T Shepard, Richard A Clendaniel, J Donald Dishman, Joel A Goebel, Dara Meldrum, Cynthia Ryan, Richard L Wallace, Nakia J Woodward Apr 2022

Vestibular Rehabilitation For Peripheral Vestibular Hypofunction: An Updated Clinical Practice Guideline From The Academy Of Neurologic Physical Therapy Of The American Physical Therapy Association, Courtney D Hall, Susan J Herdman, Susan L Whitney, Eric R Anson, Wendy J Carender, Carrie W Hoppes, Stephen P Cass, Jennifer B Christy, Helen S Cohen, Terry D Fife, Joseph M Furman, Neil T Shepard, Richard A Clendaniel, J Donald Dishman, Joel A Goebel, Dara Meldrum, Cynthia Ryan, Richard L Wallace, Nakia J Woodward

Faculty, Staff and Students Publications

BACKGROUND: Uncompensated vestibular hypofunction can result in symptoms of dizziness, imbalance, and/or oscillopsia, gaze and gait instability, and impaired navigation and spatial orientation; thus, may negatively impact an individual's quality of life, ability to perform activities of daily living, drive, and work. It is estimated that one-third of adults in the United States have vestibular dysfunction and the incidence increases with age. There is strong evidence supporting vestibular physical therapy for reducing symptoms, improving gaze and postural stability, and improving function in individuals with vestibular hypofunction. The purpose of this revised clinical practice guideline is to improve quality of care …


Metabolic Inflexibility In Youth With Obesity: Is It A Feature Of Obesity Or Distinctive Of Youth Who Are Metabolically Unhealthy?, Nour Y Gebara, Joon Young Kim, Fida Bacha, Sojung Lee, Silva Arslanian Apr 2022

Metabolic Inflexibility In Youth With Obesity: Is It A Feature Of Obesity Or Distinctive Of Youth Who Are Metabolically Unhealthy?, Nour Y Gebara, Joon Young Kim, Fida Bacha, Sojung Lee, Silva Arslanian

Faculty, Staff and Students Publications

Individuals with obesity have metabolic inflexibility with diminished fasting fat oxidation and blunted increase in respiratory quotient (RQ) in insulin-stimulated states. However, it is unclear if metabolic inflexibility is a characteristic of obesity per se or is unique to youth who have metabolically unhealthy obesity (MUO) compared with metabolically healthy obesity (MHO). We investigated metabolic flexibility in youth with MUO, MHO and normal weight (NW) and compared their metabolic characteristics. Youth (n = 188) were divided, based on cut-off points for in vivo insulin sensitivity (IS) of adolescents with NW, into 137 with MUO and 51 with MHO. Fasting hepatic …


The Role Of Palmitoleic Acid In Regulating Hepatic Gluconeogenesis Through Sirt3 In Obese Mice, Xin Guo, Xiaofan Jiang, Keyun Chen, Qijian Liang, Shixiu Zhang, Juan Zheng, Xiaomin Ma, Hongmei Jiang, Hao Wu, Qiang Tong Apr 2022

The Role Of Palmitoleic Acid In Regulating Hepatic Gluconeogenesis Through Sirt3 In Obese Mice, Xin Guo, Xiaofan Jiang, Keyun Chen, Qijian Liang, Shixiu Zhang, Juan Zheng, Xiaomin Ma, Hongmei Jiang, Hao Wu, Qiang Tong

Faculty, Staff and Students Publications

Hepatic gluconeogenesis is a crucial process to maintain glucose level during starvation. However, unabated glucose production in diabetic patients is a major contributor to hyperglycemia. Palmitoleic acid is a monounsaturated fatty acid (16:1n7) that is available from dietary sources. Palmitoleic acid exhibits health beneficial effects on diabetes, insulin resistance, inflammation, and metabolic syndrome. However, the mechanism by which palmitoleate reduces blood glucose is still unclear. SIRT3 is a key metabolism-regulating NAD+-dependent protein deacetylase. It is known that fasting elevates the expression of SIRT3 in the liver and it regulates many aspects of liver’s response to nutrient deprivation, such as fatty …


Inhibiting Type I Arginine Methyltransferase Activity Promotes T Cell-Mediated Antitumor Immune Responses, Andrew Fedoriw, Leilei Shi, Shane O'Brien, Kimberly N Smitheman, Yunfei Wang, Jiakai Hou, Christian Sherk, Satyajit Rajapurkar, Jenny Laraio, Leila J Williams, Chunyu Xu, Guangchun Han, Qin Feng, Mark T Bedford, Linghua Wang, Olena Barbash, Ryan G Kruger, Patrick Hwu, Helai P Mohammad, Weiyi Peng Apr 2022

Inhibiting Type I Arginine Methyltransferase Activity Promotes T Cell-Mediated Antitumor Immune Responses, Andrew Fedoriw, Leilei Shi, Shane O'Brien, Kimberly N Smitheman, Yunfei Wang, Jiakai Hou, Christian Sherk, Satyajit Rajapurkar, Jenny Laraio, Leila J Williams, Chunyu Xu, Guangchun Han, Qin Feng, Mark T Bedford, Linghua Wang, Olena Barbash, Ryan G Kruger, Patrick Hwu, Helai P Mohammad, Weiyi Peng

Faculty, Staff and Student Publications

Protein arginine methyltransferases (PRMT) are a widely expressed class of enzymes responsible for catalyzing arginine methylation on numerous protein substrates. Among them, type I PRMTs are responsible for generating asymmetric dimethylarginine. By controlling multiple basic cellular processes, such as DNA damage responses, transcriptional regulation, and mRNA splicing, type I PRMTs contribute to cancer initiation and progression. A type I PRMT inhibitor, GSK3368715, has been developed and has entered clinical trials for solid and hematologic malignancies. Although type I PRMTs have been reported to play roles in modulating immune cell function, the immunologic role of tumor-intrinsic pathways controlled by type I …


Development And Characterization Of Anti-Galectin-9 Antibodies That Protect T Cells From Galectin-9-Induced Cell Death, Riyao Yang, Linlin Sun, Ching-Fei Li, Yu-Han Wang, Weiya Xia, Boning Liu, Yu-Yi Chu, Laura Bover, Long Vien, Mien-Chie Hung Apr 2022

Development And Characterization Of Anti-Galectin-9 Antibodies That Protect T Cells From Galectin-9-Induced Cell Death, Riyao Yang, Linlin Sun, Ching-Fei Li, Yu-Han Wang, Weiya Xia, Boning Liu, Yu-Yi Chu, Laura Bover, Long Vien, Mien-Chie Hung

Faculty, Staff and Student Publications

Antibodies that target immune checkpoint proteins such as programmed cell death protein 1, programmed death ligand 1, and cytotoxic T-lymphocyte-associated antigen 4 in human cancers have achieved impressive clinical success; however, a significant proportion of patients fail to respond to these treatments. Galectin-9 (Gal-9), a β-galactoside-binding protein, has been shown to induce T-cell death and facilitate immunosuppression in the tumor microenvironment by binding to immunomodulatory receptors such as T-cell immunoglobulin and mucin domain-containing molecule 3 and the innate immune receptor dectin-1, suggesting that it may have potential as a target for cancer immunotherapy. Here, we report the development of two …


Exposure To Per- And Polyfluoroalkyl Substances And Markers Of Liver Injury: A Systematic Review And Meta-Analysis, Elizabeth Costello, Sarah Rock, Nikos Stratakis, Sandrah P Eckel, Douglas I Walker, Damaskini Valvi, Dora Cserbik, Todd Jenkins, Stavra A Xanthakos, Rohit Kohli, Stephanie Sisley, Vasilis Vasiliou, Michele A La Merrill, Hugo Rosen, David V Conti, Rob Mcconnell, Leda Chatzi Apr 2022

Exposure To Per- And Polyfluoroalkyl Substances And Markers Of Liver Injury: A Systematic Review And Meta-Analysis, Elizabeth Costello, Sarah Rock, Nikos Stratakis, Sandrah P Eckel, Douglas I Walker, Damaskini Valvi, Dora Cserbik, Todd Jenkins, Stavra A Xanthakos, Rohit Kohli, Stephanie Sisley, Vasilis Vasiliou, Michele A La Merrill, Hugo Rosen, David V Conti, Rob Mcconnell, Leda Chatzi

Faculty, Staff and Students Publications

BACKGROUND: Experimental evidence indicates that exposure to certain pollutants is associated with liver damage. Per- and polyfluoroalkyl substances (PFAS) are persistent synthetic chemicals widely used in industry and consumer products and bioaccumulate in food webs and human tissues, such as the liver.

OBJECTIVE: The objective of this study was to conduct a systematic review of the literature and meta-analysis evaluating PFAS exposure and evidence of liver injury from rodent and epidemiological studies.

METHODS: PubMed and Embase were searched for all studies from earliest available indexing year through 1 December 2021 using keywords corresponding to PFAS exposure and liver injury. For …


Prevalence Of Metabolic Syndrome Among The Adult Population In Western China And The Association With Socioeconomic And Individual Factors: Four Cross-Sectional Studies, Xinyin Xu, Jing Zeng, Wei Yang, Ting Dong, Xin Zhang, Shuwen Cheng, Xiaobo Zhou, Maigeng Zhou, Ling Niu, Guanghui Yi, You Li, Lishi Zhang, Yin Deng, Xianping Wu Apr 2022

Prevalence Of Metabolic Syndrome Among The Adult Population In Western China And The Association With Socioeconomic And Individual Factors: Four Cross-Sectional Studies, Xinyin Xu, Jing Zeng, Wei Yang, Ting Dong, Xin Zhang, Shuwen Cheng, Xiaobo Zhou, Maigeng Zhou, Ling Niu, Guanghui Yi, You Li, Lishi Zhang, Yin Deng, Xianping Wu

Faculty, Staff and Student Publications

Objectives: This study explored the prevalence of and individual influencing factors for metabolic syndrome (MS) as well as associated socioeconomic factors and regional aggregation.

Design: Four cross-sectional surveys were analysed for trends in MS and associations with socioeconomic and individual factors through multilevel logistic regression analyses. The risk associated with nutrient intake was also assessed through a dietary survey in 2015.

Setting: From 2010 to 2018, 8-15 counties/districts of West China were included.

Participants: A total of 28 274 adults were included in the prevalence analysis. A total of 23 708 adults were used to analyse the related factors.

Results: …


Quantifying The Effect Of Monitor Wear Time And Monitor Type On The Estimate Of Sedentary Time In People With Copd: Systematic Review And Meta-Analysis, Fiona Coll, Vinicius Cavalheri, Daniel F. Gucciardi, Sheldon Wulff, Kylie Hill Apr 2022

Quantifying The Effect Of Monitor Wear Time And Monitor Type On The Estimate Of Sedentary Time In People With Copd: Systematic Review And Meta-Analysis, Fiona Coll, Vinicius Cavalheri, Daniel F. Gucciardi, Sheldon Wulff, Kylie Hill

Research outputs 2022 to 2026

In studies that have reported device-based measures of sedentary time (ST) in people with chronic obstructive pulmonary disease (COPD), we explored if the monitor type and monitor wear time moderated the estimate of this measure. Five electronic databases were searched in January 2021. Studies were included if >70% of participants had stable COPD, and measures of ST (min/day) were collected using wearable technology. Meta-regression was used to examine the influence of moderators on ST, monitor type, and wear time. The studies identified were a total of 1153, and 36 had usable data for meta-analyses. The overall pooled estimate of ST …


Prediction Model Of 30-Days Postoperative Pneumonia In Elderly Patient Undergoing Abdominal Surgery, Noto Dwimartutie, Harini Oktadiana, Gurmeet Singh, Wifanto Saditya Jeo, Kuntjoro Harimurti Mar 2022

Prediction Model Of 30-Days Postoperative Pneumonia In Elderly Patient Undergoing Abdominal Surgery, Noto Dwimartutie, Harini Oktadiana, Gurmeet Singh, Wifanto Saditya Jeo, Kuntjoro Harimurti

Jurnal Penyakit Dalam Indonesia

Introduction. Physiologic changes in respiratory tract in elderly increase incidence of post-operative pneumonia. Post-operative pneumonia in non-thoracic surgery was found higher in abdominal surgery. This study aimed to develop a prediction model of 30-day post-operative pneumonia in elderly patients undergoing abdominal surgery.

Methods. A retrospective cohort study was conducted using elderly patient’s medical records who underwent abdominal surgery in Cipto Mangunkusumo General Hospital. Multivariate analysis using logistic regression was used to determine Odds Ratio (OR). Model’s calibration performance was determined by Hosmer-Lameshow test and its discrimination performance was determined by calculating area under the curve (AUC).

Results. Of …


Enzymatic Depletion Of Mitochondrial Inorganic Polyphosphate (Polyp) Increases The Generation Of Reactive Oxygen Species (Ros) And The Activity Of The Pentose Phosphate Pathway (Ppp) In Mammalian Cells, Vedangi Hambardikar, Mariona Guitart-Mampel, Ernest Scoma, Pedro Urquiza, Gowda Nagana, Daniel Raftery, John Collins, Maria Solesio Mar 2022

Enzymatic Depletion Of Mitochondrial Inorganic Polyphosphate (Polyp) Increases The Generation Of Reactive Oxygen Species (Ros) And The Activity Of The Pentose Phosphate Pathway (Ppp) In Mammalian Cells, Vedangi Hambardikar, Mariona Guitart-Mampel, Ernest Scoma, Pedro Urquiza, Gowda Nagana, Daniel Raftery, John Collins, Maria Solesio

Department of Orthopaedic Surgery Faculty Papers

Inorganic polyphosphate (polyP) is an ancient biopolymer that is well preserved throughout evolution and present in all studied organisms. In mammals, it shows a high co-localization with mitochondria, and it has been demonstrated to be involved in the homeostasis of key processes within the organelle, including mitochondrial bioenergetics. However, the exact extent of the effects of polyP on the regulation of cellular bioenergetics, as well as the mechanisms explaining these effects, still remain poorly understood. Here, using HEK293 mammalian cells under Wild-type (Wt) and MitoPPX (cells enzymatically depleted of mitochondrial polyP) conditions, we show that depletion of polyP within mitochondria …


Hypertension, Physical Activity And Other Associated Factors In Military Personnel: A Cross-Sectional Study, Lilian Cristina Xavier Martins Mar 2022

Hypertension, Physical Activity And Other Associated Factors In Military Personnel: A Cross-Sectional Study, Lilian Cristina Xavier Martins

Baltic Journal of Health and Physical Activity

Hypertension is a major concern in public health. In the world population over 25 years of age, its prevalence is of 40%, and studies on the amount of physical activity (PA) related to hypertension in active military personnel are scarce. To estimate the prevalence of hypertension in the Brazilian Army military personnel and to explore the association of PA levels and other risk factors.Material and methods:‪This is a cross-sectional study (N = 506). Self-reported prevalence of hypertension (outcome), PA and associated factors were examined (χ2, simple and multiple Poisson regression).Results:‪Prevalence of hypertension was lower (9.7%) than in the general population …


The Effects Of Physical Activity On Glycaemic Control In Children And Adolescents With Type 1 Diabetes Mellitus Participating In Diabetes Camps, Marcin Sikora, Anna Zwierzchowska, Marzena Jaworska, Magdalena Solich Talanda, Rafal Mikolajczyk, Aleksandra Zebrowska Mar 2022

The Effects Of Physical Activity On Glycaemic Control In Children And Adolescents With Type 1 Diabetes Mellitus Participating In Diabetes Camps, Marcin Sikora, Anna Zwierzchowska, Marzena Jaworska, Magdalena Solich Talanda, Rafal Mikolajczyk, Aleksandra Zebrowska

Baltic Journal of Health and Physical Activity

Background:‪Children with type 1 diabetes (T1D) are at high risk of having insufficient physical activity during school days and, thus, the importance of special program in promoting regular physical exercise has been largely emphasized. Therefore, this study examined the levels of physical activity and glycemia control in children with T1D, with particular focus on the relative contributions of regular physical education and physical activity program during the diabetes camp.Material and methods:‪Ninety-eight children suffering from T1D for 3.0 ±1.4 years free of diabetic complications participated in the study. Glycemia, insulin doses and diet were monitored, and physical activity was repeatedly measured …


Changes In The Body Posture Of Elder Women Under The Influence Of Various Nordic Walking Training Programs, Monika Wiech, Krzysztof Prusik, Zbigniew Ossowski, Jakub Kortas Mar 2022

Changes In The Body Posture Of Elder Women Under The Influence Of Various Nordic Walking Training Programs, Monika Wiech, Krzysztof Prusik, Zbigniew Ossowski, Jakub Kortas

Baltic Journal of Health and Physical Activity

Background:‪One of the effects of involution is the change in the body posture. Muscles lose their flexibility and strength, causing the typical changes in body posture of the elderly. Hyperkyphosis is a typical feature of the posture, which leads to serious health problems. The aim of the study was to analyse changes in the body posture of elderly women who took part in diversified Nordic walking training.Material and methods:‪The study group comprised 90 elderly women divided into two experimental groups and control. The main method was an experiment. The tested women took part in a 6-month Nordic walking training cycle. …


Incidence Of Overweight And Obesity In Women Aged 20–59 Years From The Świętokrzyskie Region, Andrzej Jopkiewicz, Stanislaw Bogdan Nowak Mar 2022

Incidence Of Overweight And Obesity In Women Aged 20–59 Years From The Świętokrzyskie Region, Andrzej Jopkiewicz, Stanislaw Bogdan Nowak

Baltic Journal of Health and Physical Activity

Background:‪The occurrence of overweight and obesity is a complex phenomenon, determined by genetic, metabolic and environmental factors. This is why, despite the continuous progress in treating obesity, it seems justified to indicate its diversification and the need for prevention and for developing a strategy of action at the level of entire populations. The aim of the study was to evaluate the incidence of overweight and obesity in women aged 20–59 years according to selected socio-economic factors.Material and methods:‪The study used a combination of nonprobability and random sampling and it encompassed 547 women from the Świętokrzyskie Region. The research methods included …


The Effect Of Vitamin D3 On The Osteointegration Of Dental Implants, Grzegorz Trybek, Magda Aniko Wlodarczyk, Jakub Kwiatek, Olga Preuss, Andrzej Brodkiewicz, Andrzej Sinicyn, Anna Grzywacz Mar 2022

The Effect Of Vitamin D3 On The Osteointegration Of Dental Implants, Grzegorz Trybek, Magda Aniko Wlodarczyk, Jakub Kwiatek, Olga Preuss, Andrzej Brodkiewicz, Andrzej Sinicyn, Anna Grzywacz

Baltic Journal of Health and Physical Activity

Dental surgeons, maxillofacial surgeons and implantologists are increasingly interested in the effects of vitamin D on bone metabolism and the immune system. The correct concentration of this prohormone potentially correlates with success at each stage of osteointegration of endosseous implants.‪A review of literature related to the topic of the paper.‬‪A suitable level of vitamin D3 is crucial from the day of surgery. It influences the modulation of the immune system – increases the production of cathelicidin and defensin, and reduces the expression of proinflammatory cytokines. It also has a positive effect on bone metabolism in osteo-suppression via the induction of …


Paediatric Physical Activity And Health: Moving Towards A Measure Of Quality, Cain C.T. Clark, Claire M. Barnes Mar 2022

Paediatric Physical Activity And Health: Moving Towards A Measure Of Quality, Cain C.T. Clark, Claire M. Barnes

Baltic Journal of Health and Physical Activity

It is clear that physical activity, holistically, is linked with several positive factors through the life course. There exists a large evidence base for physical activity quantity, yet there has been little integration of physical activity qualities, and whilst qualityis a nebulous term, recent developments in literature suggest it may be a viable measure in the characterisation of physical activity. The purpose of the study was to comprehensively review the development towards a measure of physical activity quality.‪A review of literature was conducted using online databases: Web of Science, PubMed and Google Scholar. A narrative review was subsequently prepared on …


Changes In Body Composition Of Children Aged Of 9 To 12 Years With Excess Body Weight Under The Influenceof Eight-Week Workout, Tomasz Dudziak, Zbigniew Czubek, Mirosław Grabowski, Robert Urbanski Mar 2022

Changes In Body Composition Of Children Aged Of 9 To 12 Years With Excess Body Weight Under The Influenceof Eight-Week Workout, Tomasz Dudziak, Zbigniew Czubek, Mirosław Grabowski, Robert Urbanski

Baltic Journal of Health and Physical Activity

Background:‪The increasing problem of overweight and obesity in children is the reason for taking further actions leading to mass reduction, because, in contrast to adults, the consequences of this pathology in young people are still not well known. The intervention actions that can lead to reduction in mass are not easy to find in literature, and their long-term effects are unknown. The aim of this research was to define the changes in body composition of children with excess body mass after eight-week high intensity workout.Material and methods:‪The study was conducted on 47 children aged 9‒12 years who were overweight or …


An Effect Of 12-Week Nordic Walking Training On The Body Structure And Composition In Young Women, Malgorzata Charmas, Krzysztof Piech, Lidia Kosek Mar 2022

An Effect Of 12-Week Nordic Walking Training On The Body Structure And Composition In Young Women, Malgorzata Charmas, Krzysztof Piech, Lidia Kosek

Baltic Journal of Health and Physical Activity

Background: ‪The main aim was to analyse the structure and body composition in untrained women after 12-week Nordic walking training. Material and methods: ‪26 women were divided into two groups: an EG-experimental group (n = 13) and a CG-control group (n = 13). The EG took part in 12-week Nordic walking training. All participants were examined twice: at the beginning and after the experiment. Body mass, waist and hips circumference; analysis of body composition (BIA method): BMI, body cell mass (BCM), total body (TBW), extracellular (ECW) and intracellular water (ICW); fat (FM), free fat (FFM) and muscle (MM) mass were …


Il-6 And Il-1Β Responses To A Carbohydrate-Electrolyte Drink In Orienteering Athletes, Gokhan Ipekoglu, Suleyman Gonulates, Fatmanur Er, Metin Yaman, Selma Karacan, Banu Cayci, Filiz Colakoglu Mar 2022

Il-6 And Il-1Β Responses To A Carbohydrate-Electrolyte Drink In Orienteering Athletes, Gokhan Ipekoglu, Suleyman Gonulates, Fatmanur Er, Metin Yaman, Selma Karacan, Banu Cayci, Filiz Colakoglu

Baltic Journal of Health and Physical Activity

Background:‪This study was conducted to determine acute effects of carbohydrate-electrolyte (CHO-E) found in sports drinks, ingested just before an orienteering competition, on the levels of plasma IL-6 and IL-1β cytokine.Material and methods:‪The study was conducted in a randomized, double-blind design, including 23 elite orienteering athletes who volunteered to participate. Following the collection of resting specimens of blood, the experimental group (n = 12) was administered a sports drink containing CHO-E, while the placebo group (n = 11) was administered 500 ml of plain water. The subjects were asked to finish the orienteering competition. Results:‪IL-1β level in the 24th hour after …


Changes In Emg Activity Of The Prime Movers During 10 Sets Of The Flat Bench Press Performed To Concentric Failure, Katarzyna Stronska, Marta Trebert, Artur Golas, Adam Maszczyk, Aleksandra Pięta, Florentyna Tyrala, Patricia Fischerova, Adam Zajac Mar 2022

Changes In Emg Activity Of The Prime Movers During 10 Sets Of The Flat Bench Press Performed To Concentric Failure, Katarzyna Stronska, Marta Trebert, Artur Golas, Adam Maszczyk, Aleksandra Pięta, Florentyna Tyrala, Patricia Fischerova, Adam Zajac

Baltic Journal of Health and Physical Activity

Background: The bench press (BP) is a complex exercise of the upper body in which great external loads requiring high neuromuscular activity can be lifted. Electromyography (EMG) is a study of the muscle function through the inquiry of the electrical signal the muscles emanate. The aim of the present study was to analyse changes in EMG activity of the prime movers during 10 sets of the flat bench press. Material and methods: Ten male athletes representing different sport disciplines, experienced in resistance training took part in the study. Results: In the first set, all of the tested muscles increased their …


Health Behaviours As Mediators Of Relationships Between The Actual Image And Real And Ideal Images Of One’S Own Body, Anna Lysak, Dominika Wilczynska, Anna Walentukiewicz, Magdalena Podczarska-Glowacka, Karol Karasiewicz Mar 2022

Health Behaviours As Mediators Of Relationships Between The Actual Image And Real And Ideal Images Of One’S Own Body, Anna Lysak, Dominika Wilczynska, Anna Walentukiewicz, Magdalena Podczarska-Glowacka, Karol Karasiewicz

Baltic Journal of Health and Physical Activity

Background: Health behaviours are consolidated and modified throughout human life; however, adolescence is a significant stage in the process of acquiring them. One of the identifiers of the represented health behaviours is a proper level of body fat influenced by self-assessment of own image. Material/Methods: The authors considered relationships between the real image, health behaviours and self-assessment of own appearance; these were analysed using a sample of randomly selected 830 adolescents. The body composition analysis was conducted by means of bioelectrical impedance, assessment of self-image was done with Stunkard’s Figure Rating Scale, and assessment of health behaviours was done with …


Validation Of Accelerometer For Measuring Physical Activity In Free-Living Individuals, George O. Agogo, Hilko Van Der Voet, Paul J.M. Hulshof, Pieter Van ’T Veer, Laura Trijsburg, Fred A. Van Eeuwijk, Hendriek C. Boshuizen Mar 2022

Validation Of Accelerometer For Measuring Physical Activity In Free-Living Individuals, George O. Agogo, Hilko Van Der Voet, Paul J.M. Hulshof, Pieter Van ’T Veer, Laura Trijsburg, Fred A. Van Eeuwijk, Hendriek C. Boshuizen

Baltic Journal of Health and Physical Activity

Background: The aim of this research was to validate a triaxial GT3X accelerometer against doubly labelled water for measuring total energy expenditure (TEE) in a study of free-living Dutch adults and to compare the two prediction equations used to calculate accelerometer derived activity related energy expenditure. Material/Methods: We used a measurement error model to estimate bias in the mean TEE, a correlation coefficient between measured and true TEE (a validity coefficient, which quantifies loss of statistical power to detect association) and the attenuation factor (which quantifies bias in the association), with and without conditioning on age, sex and BMI. We …


Factors Influencing Family Health History Collection Among Young Adults: A Structural Equation Modeling, Ming Li, Shixi Zhao, Yu Yu Hsiao, Oi Man Kwok, Tung-Sung Tseng, Lei Shih Chen Mar 2022

Factors Influencing Family Health History Collection Among Young Adults: A Structural Equation Modeling, Ming Li, Shixi Zhao, Yu Yu Hsiao, Oi Man Kwok, Tung-Sung Tseng, Lei Shih Chen

School of Public Health Faculty Publications

Family health history (FHH) can serve as an entry point for preventive medicine by providing risk estimations for many common health conditions. College is a critical time for young adults to begin to understand the value of FHH collection, and to establish healthy behaviors to prevent FHH-related diseases. This study seeks to develop an integrated theoretical framework to examine FHH collection behavior and associated factors among college students. A sample of 2670 college students with an average age of 21.1 years completed a web-based survey. Less than half (49.8%) reported actively seeking FHH information from their family members. Respondents’ knowledge …


Vitamin C Reduces Igf-1 And Vegf Signaling In Retinal Endothelial Cells, Jonathon Reynolds Mar 2022

Vitamin C Reduces Igf-1 And Vegf Signaling In Retinal Endothelial Cells, Jonathon Reynolds

Annual Research Symposium

No abstract provided.


Healthy Aging: Quality Of Life And Health Behaviours In Students Of The University Of The Third Age – A Preliminary Study, Justyna Krzepota, Dorota Sadowska, Beata Florkiewicz Mar 2022

Healthy Aging: Quality Of Life And Health Behaviours In Students Of The University Of The Third Age – A Preliminary Study, Justyna Krzepota, Dorota Sadowska, Beata Florkiewicz

Baltic Journal of Health and Physical Activity

Background: Previous studies have revealed high prevalence of students exhibiting unhealthy behaviour, such as insufficient physical activity during their transitional phase from school to university. Research shows that students’ health is worse compared to non-student pears. However, health and its determinants in specific subgroups, such as students –future teachers, have remained largely unexplored. In contemporary society, teachers are expected to fulfil the role of health educators regardless of the subject they teach in school. So they may maintain good health potential and develop healthy lifestyle themselves. The present study aims to estimate the health status of first-year students at the …