Digital Commons Network^™

Bivalirudin Versus Unfractionated Heparin For Anticoagulation During Ecmo: Systematic Review And Random-Effects Meta-Analysis Of Observational Comparative Studies, Yves Najm Mrad, Snehalkumar Patel

Gulf Coast Division GME Research Day 2026

No abstract provided.

A Rare Case Of Invasive Group A Streptococcus Bacteremia, Extensive Streptococcal Myositis, And Septic Knee Arthritis, Cristina Lee, Morgan Seaton, Christina Mie Minami, Bailey Weidner, Dmitriy Scherbak

Continental and Mountain Divisions GME Resarch Day 2026

No abstract provided.

Refractory Status Epilepticus After Hair Transplant: A Case Of Lidocaine Toxicity In A Post-Craniotomy Patient, Sarai Arbus, Cheyenne Lockwood, Max Wei, Andrew Labelle

Continental and Mountain Divisions GME Resarch Day 2026

No abstract provided.

Nitrous Oxide And Hirayama: A Special Case, Sierra Sandler, Natasha Hamilton, Elena Salikhova-Neace, Jeannette Betz, Alexis Taylor

Continental and Mountain Divisions GME Resarch Day 2026

No abstract provided.

Diplopia In Metastatic Hepatocellular Carcinoma With Spread To The Sphenoid Sinus, Elena Salikhova-Neace, Anna Belits, Petros Keoseyan, Ethan Mccarty, Judd Jensen, Katrina Lancaster-Shorts, Emily Lampe

Continental and Mountain Divisions GME Resarch Day 2026

No abstract provided.

Bickerstaff Brainstem Encephalitis With Miller-Fischer Syndrome Following Campylobacter Infection, Jason Hall, Weston Durland, Brandon West, Dmitriy Scherbak

Continental and Mountain Divisions GME Resarch Day 2026

No abstract provided.

Use Of Bilateral Shouldice Repair For A Hydrocele Of The Canal Of Nuck Type I, David Anderson, Jay Lavrich, Kaitlan Weppner, Bradley Wise

Continental and Mountain Divisions GME Resarch Day 2026

No abstract provided.

A Study On Metastatic Primary Lung Adenocarcinoma In A Marijuana Smoker, Sarah Hendee, Cristina Lee, Maria Aguirre, Dmitriy Scherbak

Continental and Mountain Divisions GME Resarch Day 2026

No abstract provided.

Tylenol Or Toradol? Iv Acetaminophen Vs. Parenteral Ketorolac For Prehospital Analgesia, Conrad Stallings, Kevin Crocker, Michael Wells, Nick Smith, Casey Patrick

Gulf Coast Division GME Research Day 2026

No abstract provided.

When Arteries Twist And Kidneys Shrink: A Case Of Fmd With Ruq Pain, Brian Nguyen, Ephrem Demie, Jeffrey Lesser, Rajeev Raghavan

Gulf Coast Division GME Research Day 2026

No abstract provided.

Severe Hypertriglyceridemia As A Potential Precipitant Of Acute Ischemic Stoke: A Case Report, Anusha Putta, Anush Agarwal, Hafez Golzarian

Gulf Coast Division GME Research Day 2026

No abstract provided.

Beware Of Bears: Severe Hydronephrosis & Urinary Retention Hidden Behind A Uti, Bjorn Sorensen, Victoria Jackson, Carissa Ford

Gulf Coast Division GME Research Day 2026

No abstract provided.

Septic Shock And Cardiac Arrest Secondary To Delayed Traumatic Jejunal Transection, Esra Shurbjy, Rasheed Lawal

Gulf Coast Division GME Research Day 2026

No abstract provided.

Tackling Tele Box Shortage Via Educational Initiative, Guntash Khasria, Bushra Ambreen

Gulf Coast Division GME Research Day 2026

No abstract provided.

Disseminated Cryptococcal Meningoencephalitis In A Severely Immunocompromised Patient With Lupus Nephritis, Sumon Khalique, Emaan Ul Haque, Randy Vo, Bayan Zafar

Gulf Coast Division GME Research Day 2026

No abstract provided.

Improving False Code Blue Rates In The Hospital, Edrianna Mae Ablola, Muhammad Siddiqi, Veronica Phung, Sivatej Sarva

Gulf Coast Division GME Research Day 2026

No abstract provided.

Under-Representation Of Women And Minorities In Structural Heart Trials And Practice: A Systematic Review, Yves Najm Mrad, Ahmad Al-Taweel, Bahaeddin Shabaneh

Gulf Coast Division GME Research Day 2026

No abstract provided.

A Case Report Of A Rare Skin Lesion: Malignant Or Benign?, Anila Punjwani, Shane Sweeney, Pierre Khoury, Mike Liang

Gulf Coast Division GME Research Day 2026

No abstract provided.

Accelerating Quality Improvement In Cabg Surgery: A Real-Time Rapid-Cycle Process Improvement Tool Guided By The Publicly Available Sts Risk Calculator, John G. Byrne, Farhaan Chaugle, Waleed Asger, Aaliyah Willis, Shelby Derose, Rachel Jones, Hannan Chaugle

Gulf Coast Division GME Research Day 2026

No abstract provided.

Isolated Clonidine Ingestions In Pediatric Patients, Spencer Greene, Caleb King, Sharan Campleman

Gulf Coast Division GME Research Day 2026

No abstract provided.

Redo-Tavr Vs Tavr Explant Vs Redo-Savr: Comparative Outcomes In Failed Transcatheter Bioprostheses, Yves Najm Mrad, Ahmad Al-Taweel, Bahaeddin Shabaneh

Gulf Coast Division GME Research Day 2026

No abstract provided.

Successful Retrieval Of Embolized Ventricular Septal Occluder Device, Aswin Srinivasan, Mukhtar Al-Saadi, Negar Niknam, Alexander Rhodes, Pranav Loyalka

Gulf Coast Division GME Research Day 2026

No abstract provided.

A Novel Less Invasive Single Port Pulsatile Ventricular Assist Device, Li Li, Jinsong Chen, Zhongjiang Zhuang, Stephen Topaz, Masashi Kawabori, Joseph B. Zwischenberger, Cherry Ballard-Croft, Dongfang Wang

Surgery Faculty Publications

A less invasive paracorporeal single port pulsatile ventricular assist device (sppVAD) was developed for cardiogenic shock. This compact sppVAD includes a valved single lumen cannula (VSLC), valveless single port diaphragm displacement pump (spDDP), and portable console. A 33/27 Fr VSLC was fabricated for mock loop testing, a 28/25 Fr VSLC was made for 6 hours sheep testing (n = 5, 44–52 kg), and valveless spDDP with portable console was made. The sppVAD (33/27 Fr VSLC) achieved 6.2 L/min flow in mock loop. In sheep, the 28/25 Fr VSLC was inserted without cardiopulmonary bypass from apex to ascending aorta within 1 …

Hydroxyurea Pharmacokinetics In Children With Sickle Cell Anemia Across Different Global Populations, Alexandra Power-Hays, Kathryn Mcelhinney, Thomas Williams, George Mochamah, Peter Olupot-Olupot, George Paasi, Marvin Reid, Angela Rankine-Mullings, Robert Opoka, John Chandy

Paediatrics and Child Health, East Africa

Hydroxyurea provides effective disease-modifying treatment for people with sickle cell anemia (SCA), especially when escalated to maximum tolerated dose (MTD), but has wide interpatient dosing variability due to pharmacokinetic (PK) differences. Whether hydroxyurea PK parameters differ among children with SCA in different global regions is unknown. We compared hydroxyurea PK parameters among children with SCA from five clinical trials: HUSTLE (USA, NCT00305175), TREAT (USA, NCT02286154), NOHARM (Uganda, NCT01976416), REACH (Uganda and Kenya, NCT01966731), and EXTEND (Jamaica, NCT02556099). Key hydroxyurea PK parameters were determined using HdxSim™, a validated hydroxyurea PK-software program. The results were compared across regions by one way analysis …

Investigating Neonatal Sepsis: Anti-Infectives, Diagnostics And Guidelines Used In Health Systems Across Sub-Saharan Africa – The Insights Study, Jack Louis Stanley, David Hettle, Rachel Poffley, Larisse Bolton, Emelyne Gres, Isabel Coelho, Raana Hussain, Gildas Boris Hedible, Gwendoline Lilly Chimhini, Valeriane Leroy

Paediatrics and Child Health, East Africa

Background Sepsis is a leading cause of neonatal mortality in sub-Saharan Africa (SSA), where microbiological diagnostic capacity and antibiotic access are limited. High antimicrobial resistance (AMR) rates limit the effectiveness of current treatment guidelines, with concern that available antibiotics are rarely adequate treatment for neonatal sepsis in the region.

Methods A cross-sectional online survey was electronically distributed in English, French and Portuguese to neonatal clinicians across SSA between April and June 2025. Questions focused on the management of neonatal sepsis including diagnostic, antibiotic and guideline use. Responses were analysed descriptively and presented as percentages of the total number of responses. …

Evaluation Of Peptides And Peptide–Doxorubicin Conjugates Designed And Synthesized For Targeting Triple-Negative Breast Cancer Via Cell-Surface Receptors, Shih-Jing (Jane) Yao

Pharmaceutical Sciences (PhD) Dissertations

A significant problem faced in oncology is the lack of chemotherapeutic agents that are tumor site-specific, resulting in reduced therapeutic efficacy and unintended infliction of harm to surrounding healthy tissues and cells that often lead to serious side effects. Current strategies being explored to circumvent this issue aim to refine delivery of  chemotherapeutic agents specifically to tumor sites, which may be achieved via conjugation of these agents to biomarker-specific ligands. This forms the foundation of ligand-targeted drug delivery. Among different breast cancers, treatment of the triple-negative breast cancer (TNBC) subtype has been particularly challenging, largely due to the absence of …

Chronic In Utero Oxycodone Exposure Alters Placental Small Ev Proteome And Fetal Cardiomyopathy-Linked Pathways, Amin Foroughi Nezhad, Dalia Moore, Victoria L. Schaal, Tousif Ahmed Hediyal, Elizabeth Stone, Sree Kolli, Pranavi Athota, Omar Shukri, Sowmya V. Yelamanchili, Gurudutt Pendyala

Journal Articles: Anesthesiology

Aim: The rising prevalence of opioid use during pregnancy poses serious public health concerns. The placenta is a critical organ during gestation, and opioid exposure can disrupt its function and fetal development. However, the molecular mechanisms through which opioids such as oxycodone affect feto-placental development remain poorly understood. This study aimed to investigate the effects of chronic in-utero oxycodone exposure on the composition and signaling functions of placenta-derived small extracellular vesicles (PSEVs) using a rat model.

Methods: Extracellular vesicles (EVs) were isolated from placental tissue and characterized through nanoparticle tracking analysis, transmission electron microscopy, western blotting, and label-free quantitative proteomics. …

Compensatory Responses To Glaucoma Pathology In The Dorsolateral Geniculate Nucleus, Shaylah Mccool, Arnav Jain, Jennie C. Smith, Victoria L. Schaal, Gurudutt Pendyala, Sowmya V. Yelamanchili, Matthew J. Van Hook

Journal Articles: Anesthesiology

Glaucoma disrupts the conveyance of retinal signals to visual regions of the brain such as the dorsolateral geniculate nucleus (dLGN) due to degeneration of retinal ganglion cells (RGCs) and their axons. Although plasticity during development allows altered visual experience to modulate dLGN synapses and excitability, evidence for experience-dependent dLGN plasticity in adults is limited. However, glaucoma might trigger compensatory plasticity in adult dLGN, thereby compensating for diminished RGC synaptic drive. Here, we tested this theory using aged DBA/2J mice, which develop high intraocular pressure and glaucoma. In brain slice recordings, we found that diminished RGC inputs could drive robust action …

Differential Sensitivity Of Leukocyte Populations To Staphylococcus Aureus Biofilm, Nichole D. Brandquist, Tammy Kielian

Journal Articles: Pathology and Microbiology

Staphylococcus aureus is a leading cause of prosthetic joint infection (PJI) typified by biofilm formation. Anti-inflammatory granulocytic myeloid-derived suppressor cells (G-MDSCs) represent the main leukocyte population in a mouse model of S. aureus PJI, followed by neutrophils (PMNs), and macrophages (Mφs), which is also seen during human PJI. Defining how each leukocyte population responds to S. aureus biofilm vs planktonic bacteria could have important implications for how S. aureus evades immune detection to facilitate biofilm persistence. This study compared the kinetics of leukocyte death and relationship to mitochondrial ROS (mtROS) production following exposure to planktonic S. aureus or biofilm. Mφs …

Primary Dural Diffuse Large B-Cell Lymphoma: A Report Of A Rare Case And Review Of The Literature., Adetola G Mowo-Wale, Ozo Akah, Shaileshkumar Jagdishbhai Prajapati, Parita Shah, Kaushalendra Mani Tripathi, Neeraj Kancherla, Rohan Raj

Internal Medicine Resident Research

Primary dural lymphoma (PDL) is a rare subtype of primary central nervous system lymphoma (PCNSL), accounting for fewer than 1% of cases. It originates from the dura mater with no evidence of parenchymal or systemic involvement and is usually a low-grade marginal zone B-cell lymphoma (MZL). High-grade variants, including diffuse large B-cell lymphoma (DLBCL), are extremely uncommon and clinically more aggressive. We describe the case of a 65-year-old immunocompetent man who presented with progressive headaches and right-sided weakness. Brain MRI revealed a right frontoparietal dural-based enhancing lesion with a dural tail, closely mimicking meningioma on imaging. Subtotal resection was performed, …