Digital Commons Network^™

Adaptive Multimodal Biometric Fusion Algorithm Using Particle Swarm, Kalyan Veeramachaneni, Lisa Ann Osadciw, Pramod K. Varshney

Electrical Engineering and Computer Science - All Scholarship

This paper introduces a new algorithm called “Adaptive Multimodal Biometric Fusion Algorithm”(AMBF), which is a combination of Bayesian decision fusion and particle swarm optimization. A Bayesian framework is implemented to fuse decisions received from multiple biometric sensors. The system’s accuracy improves for a subset of decision fusion rules. The optimal rule is a function of the error cost and a priori probability of an intruder. This Bayesian framework formalizes the design of a system that can adaptively increase or reduce the security level. Particle swarm optimization searches the decision and sensor operating points (i.e. thresholds) space to achieve the desired …

Equilibrative Nucleoside Transporter Family Members From Leishmania Donovani Are Electrogenic Proton Symporters, Alex Stein, Gayatri Vaseduvan, Nicola S. Carter, Buddy Ullman, Scott M. Landfear, Michael Kavanaugh

Biomedical and Pharmaceutical Sciences Faculty Publications

Leishmania donovani express two members of the equilibrative nucleoside transporter family; LdNT1 encoded by two closely related and linked genes, LdNT1.1 and LdNT1.2, that transport adenosine and pyrimidine nucleosides and LdNT2 that transports inosine and guanosine exclusively. LdNT1.1, LdNT1.2, and LdNT2 have been expressed in Xenopus laevis oocytes and found to be electrogenic in the presence of nucleoside ligands for which they mediate transport. Further analysis revealed that ligand uptake and transport currents through LdNT1-type transporters are proton-dependent. In addition to the flux of protons that is coupled to the transport reaction, LdNT1 transporters mediate a variable constitutive proton …

Health Professions Division Catalog 2003-2004, Nova Southeastern University

Health Professions Divisions Course Catalogs and Course Descriptions

No abstract provided.

The Ca2+ Dynamics Of Isolated Mouse Β-Cells And Islets: Implications For Mathematical Models, Min Zhang, Paula Goforth, Richard Bertram, Arthur Sherman, Leslie S. Satin

Pharmacology and Toxicology Publications

ABSTRACT

[Ca²⁺]_i and electrical activity were compared in isolated β-cells and islets using standard techniques. In islets, raising glucose caused a decrease in [Ca²⁺]_i followed by a plateau and then fast (2–3 min⁻¹), slow (0.2–0.8 min⁻¹), or a mixture of fast and slow [Ca²⁺]_i oscillations. In β-cells, glucose transiently decreased and then increased [Ca²⁺]_i, but no islet-like oscillations occurred. Simultaneous recordings of [Ca²⁺]_i and electrical activity suggested that differences in [Ca²⁺]_i signaling are due to …

Relationships Between Human Auditory Cortical Structure And Function, Deborah A Hall, Heledd C Hart, Ingrid Johnsrude

Brain and Mind Institute Researchers' Publications

The human auditory cortex comprises multiple areas, largely distributed across the supratemporal plane, but the precise number and configuration of auditory areas and their functional significance have not yet been clearly established. In this paper, we discuss recent research concerning architectonic and functional organisation within the human auditory cortex, as well as architectonic and neurophysiological studies in non-human species, which can provide a broad conceptual framework for interpreting functional specialisation in humans. We review the pattern in human auditory cortex of the functional responses to various acoustic cues, such as frequency, pitch, sound level, temporal variation, motion and spatial location, …

Analysis Of Gene × Environment Interactions In Sibships Using Mixed Models, Jill S. Barnholtz-Sloan, Laila M. Poisson, Steven W. Coon, Gary A. Chase, Benjamin A. Rybicki

Wayne State University Associated BioMed Central Scholarship

Abstract

Background

Gene × environment models are widely used to assess genetic and environmental risks and their association with a phenotype of interest for many complex diseases. Mixed generalized linear models were used to assess gene × environment interactions with respect to systolic blood pressure on sibships adjusting for repeated measures and hierarchical nesting structures. A data set containing 410 sibships from the Framingham Heart Study offspring cohort (part of the Genetic Analysis Workshop 13 data) was used for all analyses. Three mixed gene × environment models, all adjusting for repeated measurement and varying levels of nesting, were compared for …

The Role Of Ap-1 Transcription Complex In Retinoic Acid-Dependent B16 Melanoma Cell Growth Arrest And Differentiation, Ying Huang

Theses, Dissertations and Capstones

Our laboratory has been studying the effects of all-trans retinoic acid (atRA) on the growth and differentiation of the B16 mouse melanoma cells. RA inhibits both anchorage-dependent and –independent growth and stimulates melanin production in B16 cells, which are accompanied by an increase in AP-1 activity. To further investigate the RA-induced AP-1 activity, I established clones of B16 stably expressing an AP-1-luciferase reporter gene. Treatment of these clones with phorbol dibutyrate (PDB), a known activator of AP-1, rapidly increased AP-1 activity which reached its maximum level at 2-4 h and returned to baseline level by 24 h. In contrast, RA …

Zo1 As A Factor In The Remodeling Of Myocardial Gap Junctions, Ralph John Barker

MUSC Theses and Dissertations

The remodeling of connexin43-containing gap junctions (GJs), as defined by changes in size, distribution, or function, is a prominent feature of both the developing and diseased myocardium. During postnatal development of the mammalian ventricle, there is a progressive remodeling of GJs into intercalated disks. This change in GJ quantity and distribution is correlated with alterations in the velocity and anisotropy of impulse spread within differentiating myocardium. Orderly distribution of GJs is perturbed in many cardiac diseases, and reemergence of immature patterns of myocyte coupling may be a factor in the arrhythmogenic potential attending such pathologies. Although mechanisms responsible for this …

Structural Analyses Of Phycodnaviridae And Iridoviridae, Alan A. Simpson, Narayanasamy Nandhagopal, James L. Van Etten, Michael G. Rossmann

Nebraska Center for Virology: Faculty Publications

The Phycodnaviridae, Iridoviridae and related viruses, with diameters of 1500±2000 A Ê , are formed from large trigonal arrays of hexagonally close-packed capsomers forming the faces of icosahedra [Yan et al. (2000), Nature Struct. Biol. 7, 101-103; Nandhagopal et al. (2002), Proc. Natl Acad. Sci. USA, 99, 14758-14763]. Caspar and Klug predicted that such structures could be assembled from hexameric capsomers [Caspar & Klug (1962), Cold Spring Harbor. Symp. Quant. Biol. 27, 1-24], as was subsequently found in numerous icosahedral viruses. During the course of evolution, some viruses, including the virus families …

Isovolumetric Regulation In Mammal Cells: Role Of Taurine, B. Ordaz, R. Franco, National University Of Mexico Tuz

School of Veterinary and Biomedical Sciences: Faculty Publications

The ability to regulate cell volume is an ancient conserved trait present in essentially all species through evolution. The maintenance of a constant cell volume is a homeostatic imperative in animal cells. Changes in cell water content affecting the concentration of intracellular messenger molecules impair the complex signaling network, crucial for cell functioning and intercellular communication. Although the renal homeostatic mechanisms exert a precise control of extracellular fluid osmolarity, this is challenged in a variety of pathological situations. The intracellular volume constancy is continuously compromised by the generation of local and transient osmotic microgradients, associated with nutrients uptake, secretion, cytoskeleton …

The Role Of Oxidative Stress In Alzheimer's Disease, Robin Petroze

Kaleidoscope

Over four million individuals in the United States currently suffer from Alzheimer's disease (AD), a devastating disorder of progressive dementia. Within the next several decades, AD is expected to affect over 22 million people globally. AD can only be definitively diagnosed by postmortem examination. Thus, investigation into the specific pathogenesis of neuronal degeneration and death in AD on a biochemical level is essential for both earlier diagnosis and potential treatment and prevention options. Overproduction of amyloid [3-peptide (A[3) in the brain leads to both free radical oxidative stress and toxicity to neurons in AD. My undergraduate biochemical studies with regard …

The Relationship Between Thigh Muscle Size And 1rm Squat Strength Among Bodybuilders, Powerlifters, And Olympic Weightlifters, James Dinaso

Masters Theses

The purpose of this study was to determine if a significant difference exists in the relationship between measures of muscle size and strength among elite bodybuilders, powerlifters, and Olympic weightlifters. Fifteen male subjects between the ages of 16 and 48 years participated in the study. All three subject groups, Olympic weightlifters (OWL, n=5), powerlifters (PL, n=5), and bodybuilders (BB, n=5), were highly trained and currently involved in competition training. All test subjects were of similar body weight and weighed between 76-96 kilograms. Measures of body weight, body composition (bioelectrical impedence), shoulder width, thigh circumference (proximal, distal, and mid-thigh), and thigh …

Quantification Of The Fli1 Gene Expression By Real-Time Quantitative Rt-Pcr, Hakan Savli, Sema Sirma, Uğur Özbek

Turkish Journal of Medical Sciences

In this study, quantification levels were investigated to define alterations in the expression of the FLI1 gene on acute promyelocytic leukemia (APL), which is characterized by a reciprocal t(15,17) translocation of fusing the PML gene to the retinoic acid receptor alpha (RAR alpha) gene. The FLI1 gene plays an important role in several signal transduction pathways, and is involved in the normal regulation of myeloid hematopoiesis and leukomogenesis. We used the real-time quantitative RT-PCR (LightCycler) with SYBR Green I dye method for the labeling and analysis of the quantification of FLI1 gene RT-PCR products. Ribosomal protein S9 (RPS9) was used …

An Assessment Of Femur Growth Parameters In Human Fetuses And Their Relationship To Gestational Age, Taner Zi̇ylan, Khalil Awadh Murshed

Turkish Journal of Medical Sciences

Fetal femur length assessment has been the subject of numerous investigations. Skeletal growth disturbances, estimation of fetal gestational age, developmental abnormality and detection of certain fetal congenital anomalies, and determination of population growth characteristics have been the objectives of different investigators' studies. The purpose of this study was to evaluate the relationships between the crown-rump length (CRL) and fetal femur growth parameters and the gestational age during the second and third trimesters. Thirty dead normal immature and premature fetuses were selected from the fetal collection at the Anatomy Department of the Medical School, Selçuk University. Depending on the fetal CRL …

Anti-Hev Antibody Prevalence In Three Distinct Regions Of Turkey And Its Relationship With Age, Gender, Education And Abortions, Di̇lek Olcay, Can Polat Eyi̇gün, Şükrü Volkan Özgüven, İsmai̇l Yaşar Avci, Ahmet Bülent Beşi̇rbelli̇oğlu, Selma Yegane Tosun, Alaaddi̇n Pahsa

Turkish Journal of Medical Sciences

Hepatitis E virus (HEV) causes epidemics in developing countries such as India, Burma, Indonesia, Chad and China, but it causes sporadic cases in developed countries such as the U.S.A., Canada and the U.K. Turkey represents a bridge between HEV endemic and non-endemic areas, and HEV may cause epidemics in Turkey. In this study, the prevalence of HEV in three distinct regions of Turkey and its relationship with age, gender, education and abortions was investigated. Nine hundred ten randomly selected cases from three cities in three geographic regions of Turkey (Manisa from the Aegean region, Elmadağ/Ankara from Central Anatolia and Diyarbakır …

Suicide In The Province Of Eskişehir, Turkey: The Approach Of Forensic Medicine, Yasemi̇n Günay Balci, Emre Albek

Turkish Journal of Medical Sciences

In the present study, a retrospective evaluation of suicides in the province of Eskişehir in 1997-1999 is made. Investigation reports of the Central Prosecutor's Office were obtained and the demographic data of the victims as well as the judicial criteria for the classification as "suicide" were evaluated. There were 94 cases of suicide and 65 of them (69.1%) involved males. Age distribution showed a predominance in the age group of 15-34 years. Suicide in males over 55 years of age occurred more frequently than in females (p < 0.05). Causes of death in suicides included hanging in 68.0% of cases, firearm wounding in 16.0%, jumping from heights in 7.4%, drug intake in 5.3%, railway suicides in 2.2% and butane inhalation in 1.1%; 79.8% of suicides occurred in residences. In 93.6% of the cases, scene investigation reports and drawings were obtainable, while photographs of the scene or of the victim were present in 53.2% of cases. A forensic medicine specialist's inquest had been performed in all cases whilst a medico-legal autopsy had been carried out in only 29.8% of cases. Death certificates were issued following an inquest and scene investigation in 66 cases. Medico-legal autopsies were performed in 73.3% of the cases of firearm wounding, 25.0% of the cases of hanging and 6.7% of suicides committed by other means. In conclusion, we emphasize the importance of a medico-legal autopsy in all suicide cases.

A Cerebral Hydatid Cyst Case First Presenting With Gerstmann's Syndrome: A Case Report And Literature Review, Mehmet Dumlu Aydin, Nazan Aydin

Turkish Journal of Medical Sciences

umlu AYDIN^1 Nazan AYDIN^2 Departments of ^1Neurosurgery , ^2Psychiatry, Faculty of Medicine, Atatürk University, Erzurum - Turkey

A Modified Method For The Determination Of Plasma Total Homocysteine By High Performance Liquid Chromatography, Serhat Tokgöz, Cumhur Bi̇lgi̇, Erdi̇nç Çakir, M. Kemal Erbi̇l, Türker Kutluay

Turkish Journal of Medical Sciences

We have modified a high-performance liquid chromatography (HPLC) procedure for homocysteine assay using 7-fluoro-2, 1, 3-benzoxadiazole-4-sulfonamide (ABD-F) pre-column derivatization. In this study, the thiol compounds were liberated from plasma proteins by reduction with 2-mercaptoethanol (BME) and derivatized with a thiol-specific fluoregenic marker, ABD-F. The derivatives were separated by reversed-phase HPLC on a Hypersil C 18 column (4.6 x 150 mm; 5 µ) using isocratic elution with 0.1 M phosphate buffer pH 6.0 containing 8% methanol and fluorescence detection. Excitation and emission wavelengths were 386 and 516 nm. The peak of homocysteine was eluted at 413 ± 25 s. Mean within-day …

Paratesticular Solitary Fibrous Tumour: Case Report And Review Of The Literature, Nusret Akpolat, Arslan Ardiçoğlu, Seyfetti̇n Yahşi̇, A.Rahmi̇ Onur

Turkish Journal of Medical Sciences

KPOLAT^1 Arslan ARDIÇOĞLU^2 Seyfettin YAHŞİ^1 A. Rahmi ONUR^2 Departments of ^1Pathology and ^2Urology, Faculty of Medicine, Fırat University, Elazığ - TURKEY

Bacterial Translocation After Partial Hepatic Resection Under Ischemia And Reperfusion In Rats: Incidence And Time Course, Abdulkadi̇r Bedi̇rli̇, Selma Gökahmetoğlu, Kadi̇r Can Küçük, Işin Soyuer, İlkay Güler, Ömer Şakrak

Turkish Journal of Medical Sciences

Infectious complications are major causes of morbidity and mortality following major hepatic resection. We investigated in rats the incidence and time course of bacterial translocation after partial hepatectomy during ischemia and reperfusion. Forty-eight male Wistar rats weighing 230 to 280 g were studied. Partial liver warm ischemia was performed for 15 min followed by reperfusion for 15 min. During a second 15 min of ischemia, 70% hepatectomy was performed. The animals were divided into six groups of eight animals each. Animals were sacrificed 8, 16, 24, 48, 72, and 120 h after the hepatectomy. At each time point blood was …

A Review Of Polyamines And Cancer, Wayne E. Criss

Turkish Journal of Medical Sciences

of Polyamines and Cancer Wayne E. CRISS Department of Biochemistry, Faculty of Medicine and Institute of Oncology, Hacettepe University, Ankara - Turkey

Isolation And Identification Of Phenolic Acids In Malaysian Honey With Antibacterial Properties, Almahdi Melad Aljadi, Kamaruddin Mohd Yusoff

Turkish Journal of Medical Sciences

In this study the non-peroxide antibacterial factors in Malaysian honey were isolated and identified. The phenolic components were extracted from two different local floral honeys and their effects on the growth of selected pathogens were examined. A solid-phase extraction procedure was applied for the first time to recover honey phenolics. Identification was carried out via high performance liquid chromatography and gas chromatography analysis. Antibacterial activity was determined via the disc-diffusion and broth dilution assays. The phenolic fractions of gelam and coconut honeys showed potent antibacterial activities. Both honeys contain gallic, caffeic, and benzoic acids. However, gelam honey contains additional phenolic …

Vitamin D Dependent Down Regulation Of Arf1 Gene In Human Leukemia Cell Line Hl-60, Hakan Savli

Turkish Journal of Medical Sciences

VLI Department of Medical Biology, Faculty of Medicine, Kocaeli University, Kocaeli - Turkey

Severe Acute Respiratory Syndrome (Sars): The First Pandemic Of The New Century, Murat Akova

Turkish Journal of Medical Sciences

No abstract provided.

The Frequency Of Helicobacter Pylori In Various Gastric Mucosal Appearances, Mehmet Dursun, Mustafa Karabulut, Fi̇kri̇ Canoruç, Şeri̇f Yilmaz, Mehmet Yaldiz

Turkish Journal of Medical Sciences

Our purpose was to investigate whether Helicobacter pylori (Hp) has a specific mucosal appearance. Eighty-eight (female / male: 53/35) patients included in the study underwent endoscopy to determine the macroscopic appearance of their gastric mucosa. Biopsies taken from the antrum, incisura angularis and corpus of each patient were stained with toluidine blue and examined for Hp under a light microscope. Thirty were Hp negative and 58 Hp positive. Thirty-six percent of the patients had normal mucosa, 21.59% had spotty erythema in the antrum, 31.81% had a mosaic pattern in the antrum and/or corpus and 10.23% had acute duodenal ulcer. Fifty-six …

Reversible Conduction Block In Frog Sciatic Nerve For Three Different Concentrations Of Bupivacaine, Belgi̇n Büyükakilli, Ülkü Çömelekoğlu, Oya Öğenler

Turkish Journal of Medical Sciences

We examined the effects of various concentrations of the bupivacaine commonly used for spinal anaesthesia on the reversibility of conduction block in isolated frog sciatic nerves measured by the extracellular recording technique. Seventy-two isolated nerves were divided into 3 groups (n = 24), each of which was bathed in a different bupivacaine solution in a range of concentrations (10, 20 or 30 mM for 20 min). In each group, the extracellular action potentials were recorded before exposure to the bupivacaine solution to provide the control data. The extracellular action potentials were recorded after 20 min exposure to the drug by …

Multiple Infected Cerebral Hydatid Cysts Treated With Albendazole, Mehmet Dumlu Aydin, Mustafa Ertek, Hali̇l Yazgi

Turkish Journal of Medical Sciences

umlu AYDIN^1, Mustafa ERTEK^2, Halil YAZGI^3 ^1Department of Neurosurgery, Faculty of Medicine, Atatürk University, Erzurum - Turkey ^2Department of Infectious Disease, Faculty of Medicine, Atatürk University, Erzurum - Turkey 3Department of Clinical Microbiology, Faculty of Medicine, Atatürk University, Erzurum - Turkey

Haemophilus Parainfluenzae Endocarditis, Emi̇ne Alp, Orhan Yildiz, Bi̇lgehan Aygen, Bülent Sümerkan

Turkish Journal of Medical Sciences

No abstract provided.

Acute Adrenal Insufficiency In A 30-Year-Old Woman With Active Pulmonary Tuberculosis, Refi̇k Demi̇rtunç, Meli̇h Başar

Turkish Journal of Medical Sciences

MİRTUNÇ, Melih BAŞAR Department of Internal Medicine, Haydarpaşa Numune Training and Research Hospital, İstanbul - Turkey

Atophic Rhinitis : A Case Report, Ayli̇n Yücel, Orhan Aktepe, Fatma Aktepe, Fevzi̇ Sefa Dereköy

Turkish Journal of Medical Sciences

CEL^1, Orhan AKTEPE^2, Fatma AKTEPE^3, Fevzi Sefa DEREKOY^4 ^1Department of Radiology, Faculty of Medicine Afyon Kocatepe University, Afyon - Turkey ^2Department of Microbiology, Faculty of Medicine Afyon Kocatepe University, Afyon - Turkey ^3Department of Pathology, Faculty of Medicine Afyon Kocatepe University, Afyon - Turkey ^4Department of Otolaryngology, Faculty of Medicine Afyon Kocatepe University, Afyon - Turkey