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Prevalence Of Echinococcus Granulosus Detected Using Enzyme Immunoassay And Abdominal Ultrasonography In A Group Of Students Staying In A State Dormitory In Turkey, Bi̇lgi̇n Arda, Hüsnü Pullukçu, Tansu Yamazhan, Oğuz Reşat Si̇pahi̇, Sadik Tamsel, Gülgün Demi̇rpolat, Meti̇n Korkmaz

Turkish Journal of Medical Sciences

Aim: In this study our aim was to analyse the seroprevalence of cystic echinococcosis and prevalence of lesions (with abdominal ultrasonography) in a group of young adult university students staying in a state dormitory in Bornova, İzmir, Turkey. Materials and methods: The study group was consisted of 750 students (360 women, 390 men, mean age 20.92 ± 1.82 years, min 17, max 29). Informed written consent was obtained from each student and they were requested to fill a questionnaire form (sociocultural and economic condition, area of living, and demographic data). Blood sampling was performed by intravenous puncture and sera were …

Anti-Hav Seroprevalence In Turkish Military Personnel And Its Relation With Demographic Properties, Hanefi̇ Cem Gül, İsmai̇l Yaşar Avci, Ömer Coşkun, Recai̇ Oğur, Yakup Hakan Başaran, Çakir Güney, Bülent A. Beşi̇rbelli̇oğlu, Cengi̇z Han Açikel, Can Polat Eyi̇gün, Alaaddi̇n Pahsa

Turkish Journal of Medical Sciences

Aim: Turkey is a middle endemic area in terms of Hepatitis A Virus (HAV) infection. Previous studies in Turkey showed that most residents had been infected with HAV by the second decade of life. In this study we aimed to detect the anti-HAV seroprevalence rate in Turkish military personnel and its relation with demographic properties. Materials and methods: Randomly selected 1049 military personnel were enrolled in the study. All were male and their average age was 24.97 ± 6.48 (Range: 20-50) years. A questionnaire about their demographic properties was administered to and informed consent forms were obtained from each subject. …

Progression Of Binocular Vision Following Cataract Surgery*, İlknur Akyol Salman, Murat Arslankurt, Osman Dursun, Ahmet Yazici, Orhan Baykal

Turkish Journal of Medical Sciences

Aim: To investigate the progression of binocular vision of patients after cataract surgery in the early postoperative period. Materials and methods: Eighty four cataract patients were evaluated at postoperative 1 and 3 months after phacoemulsification and posterior chamber monofocal lens implantation. For the evaluation of the grades of binocular vision, synoptophore was used. Stereoscopic acuity was measured with the Titmus Stereotest. Results: Evaluation at postoperative 3 months was associated with a significantly higher proportion of patients with stereopsis (P = 0.004), better levels of stereoacuities (P < 0.001) than the evaluation at postoperative 1 month. Significantly higher visual acuities (P = 0.001) and lower interocular difference in refraction values (P = 0.023) were also noted at postoperative 3 months. The level of stereoscopic acuity was not significantly correlated with the level of visual acuity, interocular visual acuity difference, interocular difference in refraction, and the age of patients (P > 0.05). In patients without fusion, suppression was found in the operated eyes with favorable …

Fetal Malnutrition In Infants Of Smokers And Passive Smokers Assessed By Clinical Assessment Of Nutritional Status Scoring, Ayşen Kutan Fenerci̇oğlu, Güner Karateki̇n, Asi̇ye Nuhoğlu

Turkish Journal of Medical Sciences

Aim: Studies have shown that maternal smoking during pregnancy is associated with low birth weight, height and head circumference in newborns. In the present study, along with these anthropometric measures we aimed to determine fetal malnutrition (FM), which is a less known outcome of antenatal tobacco exposure. Materials and methods: Two hundred and sixty-six term singletons without anomalies were evaluated for their birth weight, height, and head circumference and for FM using the Clinical Assessment of Nutritional Status (CANS) scoring. A CANS score equal to or less than 24 is accepted as FM. Results: Smokers' (n = 84) and passive …

Effects Of Long-Term Passive Smoking On Vascular Endothelial Growth Factor And Apoptosis Markers Expression In Lens And Corneal Epithelial Cells: An Experimental Study*, Fati̇h Özcura, Sema Oruç Dündar, İbrahi̇m Meteoğlu, Mehmet Erkut Kara

Turkish Journal of Medical Sciences

Aim: To determine the effects of smoking on vascular endothelial growth factor (VEGF) expression and apoptosis in lens and corneal epithelial cells. Materials and methods: This experimental study included 38 Sprague-Dawley rats. Rats were randomly assigned into 4 groups. Groups 1 (males) and 2 (females) were exposed to smoke beginning on the 21st day after birth, whereas groups 3 (males) and 4 (females) were not exposed to smoke. At the end of the fourth month, right eyes of all rats were enucleated. Immunohistochemical analysis was performed in enucleated eyes in terms of VEGF and apoptosis markers, namely caspase-3, Bcl-X, and …

Cytotoxic Effects Of Caffeic Acid Phenethyl Ester (Cape) On The Human Multiple Myeloma Cell Line, Özgür Koru, Feri̇t Avcu, Mehmet Tanyüksel, Ali̇ Uğur Ural, Remzi̇ Engi̇n Araz, Kenan Şener

Turkish Journal of Medical Sciences

Aim: Caffeic acid phenethyl ester (CAPE) has cytotoxic, apoptotic, and antiproliferative effects on various tumor cells, and is the most active component of propolis. This study aimed to examine the in vitro effects of CAPE on the human multiple myeloma cell line. Materials and methods: CAPE was added to the ARH-77 multiple myeloma cell line and the percentage of dead cells was measured using the 3-(4,5-dimethyl-thiazoyl)-2,5-diphenyl-SH-tetrazolium bromide (MTT) assay. The percentage of live cells and growth inhibition were determined using the Trypan blue test. The percentage of IL-6 cells was determined using ELISA. Results: ARH-77 cells treated with CAPE for …

Athletes Have Faster Eye-Hand Visual Reaction Times And Higher Scores On Visuospatial Intelligence Than Nonathletes, Sedi̇ Akarsu, Erkan Çalişkan, Şenol Dane

Turkish Journal of Medical Sciences

Aim: To compare sports-related visual abilities such as hand-eye reaction time and visuospatial intelligence of athletes to nonathletes. Materials and methods: Differences in sports-related visual abilities such as hand-eye reaction time and visuospatial intelligence between athletes and nonathletes were studied in 157 male (M age = 13.9 years, SD = 1.8) and 126 female (M age = 13.9 years, SD = 1.7) high school students. Visuospatial intelligence was assessed with Cattel's Culture Fair Intelligence Test. A software package of random stimulus presentation and response recording was used for eye-hand reaction time. Results: Athletes had lower eye-hand visual reaction time (the …

Does L-Carnitine Increase Serum Tnf -Α And Igf-1 During Liver Regeneration In The Rat?, Mevlüt Pehli̇van, Abdurrahman Coşkun, Ahmet Zengi̇n, Ari̇f Aslaner, Tevfi̇k Yavuz

Turkish Journal of Medical Sciences

Aim: We sought to evaluate the effect of L-carnitine administration on the levels of IGF-1, TNF-\alpha, and lipid peroxidation during hepatic regeneration for up to 72 h in an experimental partial hepatic resection rat model. Materials and methods: Sixty rats were divided into 3 groups: control and low-dose (100 mg/kg) and high-dose (200 mg/kg) L-carnitine. Each group was divided into 2 sub groups (24 and 72 h after partial hepatectomy). Partial (70%) hepatectomy was performed after 7 days of intra-peritoneal administration of L-carnitine. After partial hepatectomy, L-carnitine was also administered to rats until sacrifice. Serum IGF-1, TNF-\alpha, and tissue malondialdehyde …

A Comparison Of Different Management Techniques For Myocardial Protection In Acyanotic Congenital Cardiac Patients, İbrahi̇m Duvan, Bariş Durukan, Alper Gürbüz, Cem Yorgancioğlu, Meti̇n Demi̇rci̇n

Turkish Journal of Medical Sciences

Aim: It has already been shown that terminal warm blood cardioplegia (TWBC) supports myocardial protection in pediatric patients when it is administered after cold blood cardioplegia. However, the myocardial protective effects of TWBC applied after cold crystalloid cardioplegia (CCC) is still a subject of debate. Materials and methods: Twenty acyanotic congenital cardiac patients were randomly divided into 2 groups of 10. In the control group (CG), moderate hypothermia, topical cooling, and cold crystalloid cardioplegia were performed for the protection of the myocardium. In the other group (TWBCG), the same procedure was supported using TWBC just before the unclamping of the …

Erythrocyte Tao And Tbars Levels In Patients Who Suffered Missed Miscarriage, Ayşe Nur Aksoy, Hülya Aksoy, Nuri̇nni̇sa Öztürk, Çağlar Bulut

Turkish Journal of Medical Sciences

Aim: Missed miscarriage is a pregnancy-related condition, and lipid peroxidation and alterations in antioxidant levels may be of importance in the pathogenesis of this disorder. The aim of the study was to assess whether erythrocyte total antioxidant activity (TAO) and thiobarbituric acid reactive substance (TBARS) levels altered in patients who suffered missed miscarriage. Materials and methods: We measured levels of TAO and TBARS, as a lipid peroxidation marker, in erythrocytes of women with a diagnosed missed miscarriage (n = 36) during 7-16 weeks of pregnancy. The control group consisted of women (n = 34) with uncomplicated pregnancy similarly matched for …

Molecular Typing Of Methicillin-Resistant Staphylococcus Aureus Isolated From Bloodstream Infections In A University Hospital, Gülay Yetki̇n, Çi̇gdem Kuzucu, Bengül Durmaz, Riza Durmaz, Zeynep Çi̇zmeci̇, Lati̇fe İşeri̇

Turkish Journal of Medical Sciences

Aim: Bloodstream infections due to methicillin-resistant Staphyococcus aureus (MRSA) strains are one of the major problems in many hospitals. Molecular typing provides very useful information about the origin and the spreading ways of strains. The aim of the present study is to assess the clonal relationship amongst MRSA strains isolated from bloodstream infections of patients in Turgut Özal Medical Center, İnönü University in Turkey. Materials and methods: A total of 37 consecutive MRSA strains were identified from the blood cultures from January to December 2003. Methicillin resistance was confirmed with amplification of the mecA gene by polymerase chain reaction (PCR). …

Burnout At A Bone Marrow Transplantation Unit In Turkey: Effects Of Interactive Psychoeducational Seminars, Ayşegül Yilmaz, Ati̇lla Soykan, Tuğba Ayaz, Elmas İnce Kale, Günhan Gürman, Hakan Kumbasar

Turkish Journal of Medical Sciences

Aim: Health staff working at bone marrow transplantation units (BMTUs) is found to be at a higher risk for suffering from burnout. This paper reports a critical assessment of how burnout level of the health staff working at a bone marrow transplantation unit changes after psychoeducational seminars. Materials and methods: The study was conducted by the Consultation Liaison Psychiatry Division at the BMTU of the Department of Hematology at Ankara University, School of Medicine. Sixty-one health staff members (67%) working at the BMTU filled out socio-demographic and occupational data form, and validated Turkish versions of Maslach Burnout Inventory (MBI), Hospital …

Evaluation And Follow-Up Of Cases Diagnosed As Child Abuse And Neglect At A Tertiary Hospital In Turkey, Ülkü Tiraş, Di̇lek Di̇lli̇, Yildiz Dallar, Resmi̇ye Oral

Turkish Journal of Medical Sciences

Aim: Data on child maltreatment in Turkey would appear to be scarce. This manuscript aims to address the prevalence and severity of child maltreatment in Turkey. Materials and methods: We report on 215 cases at the Ministry of Health’s Ankara Training and Research Hospital that were followed-up by the multidisciplinary Child Protection Team (CPT) between 1 January 2001 and 31 December 2005. The data collected on subjects included characteristics of the victims and the perpetrators, family demographics, maltreatment types, medical findings, mortality rate, and outcomes for the victim and the perpetrator. Results: Age and gender distribution of the victims were …

Primate Phylogenomics: Developing Numerous Nuclear Non-Coding, Non-Repetitive Markers For Ecological And Phylogenetic Applications And Analysis Of Evolutionary Rate Variation, Zuogang Peng, Navin Elango, Derek E. Wildman, Soojin V. Yi

Wayne State University Associated BioMed Central Scholarship

Abstract

Background

Genetic analyses are often limited by the availability of appropriate molecular markers. Markers from neutrally evolving genomic regions may be particularly useful for inferring evolutionary histories because they escape the constraints of natural selection. For the majority of taxa however, obtaining such markers is challenging. Advances in genomics have the potential to alleviate the shortage of neutral markers. Here we present a method to develop numerous markers from putatively neutral regions of primate genomes.

Results

We began with the available whole genome sequences of human, chimpanzee and macaque. Using computational methods, we identified a total of 280 potential …

Incorporation Of Membrane-Bound, Mammalian-Derived Immunomodulatory Proteins Into Influenza Whole Virus Vaccines Boosts Immunogenicity And Protection Against Lethal Challenge, Andrew S. Herbert, Lynn Heffron, Roy Sundick, Paul C. Roberts

Wayne State University Associated BioMed Central Scholarship

Abstract

Background

Influenza epidemics continue to cause morbidity and mortality within the human population despite widespread vaccination efforts. This, along with the ominous threat of an avian influenza pandemic (H5N1), demonstrates the need for a much improved, more sophisticated influenza vaccine. We have developed an in vitro model system for producing a membrane-bound Cytokine-bearing Influenza Vaccine (CYT-IVAC). Numerous cytokines are involved in directing both innate and adaptive immunity and it is our goal to utilize the properties of individual cytokines and other immunomodulatory proteins to create a more immunogenic vaccine.

Results

We have evaluated the immunogenicity of inactivated cytokine-bearing influenza …

Complementary Responses To Mean And Variance Modulations In The Perfect Integrate-And-Fire Model, Joanna R. Wares, Todd W. Troyer

Department of Math & Statistics Faculty Publications

In the perfect integrate-and-fire model (PIF), the membrane voltage is proportional to the integral of the input current since the time of the previous spike. It has been shown that the firing rate within a noise free ensemble of PIF neurons responds instantaneously to dynamic changes in the input current, whereas in the presence of white noise, model neurons preferentially pass low frequency modulations of the mean current. Here, we prove that when the input variance is perturbed while holding the mean current constant, the PIF responds preferentially to high frequency modulations. Moreover, the linear filters for mean and variance …

Control Of Myosin Motor Activity And Actin Filament Translation By Alteration Of Assay Reducing Potential, Siva Krishna Nalabotu

Theses, Dissertations and Capstones

The use of biomolecular motors for nanotechnological applications has been impaired by an inability to control biomolecular motor activity in a temporal fashion. Previous data has suggested that myosin activity can be modulated by inducing changes in the degree of myosin oxidation. The hypothesis of this study is that myosin motor activity can be regulated by altering the amount of antioxidants and reducing agents present in assay solution. To test this hypothesis we systematically altered the concentration of reducing agents and examined the effects of these changes on myosin-dependent actin filament translation. Our findings indicate that myosin activity can be …

Cellular And Molecular Mechanisms Of Toxin Resistance For Endoplasmic Reticulum Translocating Toxins, Christopher Massey

Electronic Theses and Dissertations

The endoplasmic reticulum (ER) is the site of co- and post-translational modification for secretory proteins. In order to prevent vesicular transport and secretion of misfolded or misassembled proteins, a highly regulated mechanism called ER-associated degradation (ERAD) is employed. This pathway recognizes misfolded proteins in the ER lumen and targets them to the cytosol for ubiquitination and subsequent degradation via the 26S proteasome. Sec61 and Derlin-1 are ER pores through which export occurs. AB-type protein toxins such as cholera toxin (CT), Shiga toxin (ST), exotoxin A (ETA), and ricin have evolved means of exploiting the ERAD pathway in order to reach …

Bacterial Selenoproteins: A Role In Pathogenesis And Targets For Antimicrobial Development, Sarah Rosario

Electronic Theses and Dissertations

Selenoproteins are unique proteins in which selenocysteine is inserted into the polypeptide chain by highly specialized translational machinery. They exist within all three kingdoms of life. The functions of these proteins in biology are still being defined. In particular, the importance of selenoproteins in pathogenic microorganisms has received little attention. We first established that a nosocomial pathogen, Clostridium difficile, utilizes a selenoenzyme dependent pathway for energy metabolism. Following this initial characterization, we demonstrate that this pathway is linked to production of toxins by this organism. Finally, we show that interruption of selenium metabolism is a viable pathway for development of …

Iron-Induced Cerebellar Purkinje Cell Loss Is Ameliorated By Flunarizine, Ramazan Kozan, M. Ömer Bostanci, Tuncer Nacar, Ali̇ Aslan, Faruk Bağirici

Turkish Journal of Medical Sciences

Aim: In this study, we investigated the effect of intracerebroventricular-injected iron neurotoxicity on the total number of cerebellar Purkinje cells in rats and the possible neuroprotective effect of flunarizine, a piperazine-derived calcium channel blocker. Materials and Methods: Rats were divided into four groups: control, flunarizine, iron, and iron + flunarizine groups. Rats in the iron and iron + flunarizine groups received intracerebro-ventricular iron (FeCl_36H_2O, 200 mM, 2.5 µl), while those in flunarizine and iron + flunarizine groups were intraperitoneally injected with flunarizine (10 mg/kg/day) once a day after the operation for 10 days. After 10 days, all rats were perfused …

Artificial Neural Network Analysis For Prediction Of Headache Prognosis In Elderly Patients, Bahar Taşdelen, Sema Helvaci, Hakan Kaleağasi, Aynur Özge

Turkish Journal of Medical Sciences

Aim: To investigate the ability of neural networks to detect and classify the complete improvement of headache in elderly patients during the follow- up period. Materials and Methods: The multilayer perceptron (MLP), which is the most common neural network, was used to predict prognosis of headache in elderly patients. The data set was divided into training and test sets, and back-propagation algorithm was used as the learning algorithm. The accuracies of the models to predict completely improved patients at the end of 20, 40, and 60 months of follow-up were evaluated by means of the areas under the receiver operating …

Impact Of Socioeconomic Conditions And Parasitic Infection On Hemoglobin Level Among Children In Um-Unnasser Village, Gaza Strip, Bassam F. Al-Zain

Turkish Journal of Medical Sciences

Aims: A cross-sectional study was conducted to examine the impact of socioeconomic conditions and intestinal parasitic infection (IPI) on hemoglobin level among children aged 2-15 years in Um-Unnasser village, North Gaza, Palestine. Materials and Methods: The data were collected using structured questionnaire and laboratory analysis of blood and fecal samples. Results: Of 256 children, 25% were anemic and prevalence was higher in children aged below six years. Overall prevalence of IPI was 46.9%. Ascaris lumbricoides (11.3%), Giardia lamblia (8.2%), Hymenolepis nana (6.2%), Entamoeba histolytica (5.1%), Strongyloides stercoralis (2.0%), Enterobius vermicularis (2.7%), and Trichuris trichiura (0.3%) were the most frequently found, …

Comparison Of Clinical And Histopathologic Findings Of Pathergy Test With Disposable/Sharp And Nondisposable/Blunt Needles In Behcet´S Disease, Ayşe Serap Karadağ, Gülfer Akbay, Mehtap Aydin, Hesna Müzeyyen Astarci, Meral Ekşi̇oğlu

Turkish Journal of Medical Sciences

Aim: The aim of this study was to determine whether using blunt instead of sharp needles presented any advantage and whether the histopathological interpretation prevailed over the clinical interpretation. Materials and Methods: This study was performed on 60 Behçet´s disease (BD) patients and 20 control subjects. The pathergy test was applied to all subjects intradermally with sharp and blunt needles and the histopathology of each test result was studied. Results: In the active period of BD (40 patients), positive test results were obtained in 34 (85.0%) patients using blunt needles and in 13 (32.5%) using sharp needles (P = 0.0001). …

The Effect Of Dust-Mites On Nitric Oxide Production, Süleyman Yazar, Eser Kiliç, Meti̇n Atambay, Aysun Bay Karabulut, Özlem Makbule Aycan, Gülden Sönmez Tamer, Ni̇lgün Daldal

Turkish Journal of Medical Sciences

Aim: We aimed to investigate the effect of house dust mite on the level of nitric oxide in patients who had dust mite in their houses and suffering from rhinitis and/or asthma and/or eczema-like allergic symptoms and were positive for skin tests (Prick). Materials and Methods: The effect of dust-mites on nitric oxide concentration was investigated using Griess method in patients who had allergic symptoms and were positive for skin tests. Results: The plasma nitric oxide level was found to be statistically higher in patients who had dust mite in their houses and suffering from allergic symptoms and were positive …

Comparison Of Gliclazide Treatment With Diet Therapy On Acute Phase Protein Levels In Patients With Type 2 Diabetes, Ramazan Memi̇şoğullari, Fati̇h Akçay, Abdurrahman Coşkun, Uğur Korkmaz

Turkish Journal of Medical Sciences

Aims: It is known that there is a relationship between diabetic complications and chronic inflammation characterized by alterations in circulating acute phase proteins. It has been emphasized that inflammation contributes to diabetic complications and that gliclazide -an antidiabetic sulfonylurea - decreases the development of such complications. In this study, we aimed to investigate whether gliclazide or diet treatment has an effect on serum levels of acute phase reactants, markers of inflammation. Materials and Methods: Fifty-six newly diagnosed patients with type 2 diabetes and 30 clinically healthy subjects were evaluated prospectively. Twenty-six patients were treated with proper diet and daily gliclazide …

Postural Stability And Functional Capacity In Recreational Athletes With Type 1 Diabetes Mellitus, Tolga Saka, Yavuz Yildiz, Ferhat Deni̇z, Bülent Hazneci̇, Ufuk Şeki̇r, Taner Aydin

Turkish Journal of Medical Sciences

Aims: The aim of this study was to evaluate postural stability and functional capacity in recreational athletes with type 1 diabetes mellitus (T1 DM) and to compare them with healthy recreational athletes. Materials and Methods: Sixteen recreational athletes with T1 DM (21.4 ± 2.1 years of age, 174.3 ± 7 cm height, 64.5 ± 10.1 kg weight, 10.9 ± 5.3 body fat percentage [BFP]) and 19 healthy recreational athletes (21.9 ± 2.5 years of age, 173.1 ± 5.2 cm height, 66.1 ± 4 kg weight, 14.4 ± 1.5 BFP) participated in this study. Postural stability was measured by using the …

Primary Drug Resistance And Molecular Epidemiology Of The Mycobacterium Tuberculosis Strains Isolated In The Kelkit Valley, Yunus Bulut, Gülgün Yeni̇şehi̇rli̇, Bariş Otlu, Zehra Seyfi̇kli̇, Serhat Çeli̇kel, Ayşe Yilmaz, Handan İnönü

Turkish Journal of Medical Sciences

Aim: The aim of this study was to determine the primary drug resistance rates and genotypes of resistant Mycobacterium tuberculosis strains isolated in the Kelkit Valley. Materials and Methods: Primary resistance to isoniazid (INH), rifampicin (RIF), ethambutol (ETB), and streptomycin (SM) was determined with the BACTEC 460 radiometric system. Forty-eight resistant M. tuberculosis strains isolated from tuberculosis patients living in the Kelkit Valley were genotyped using the spoligotyping method. Results: Approximately 11.6% of the strains were resistant against at least one major drug, and 8.3% were resistant against more than one drug. Single-drug resistance for INH, ETB, SM, and RIF …

Reliability Of A Functional Test Battery Evaluating Functionality, Proprioception And Strength Of The Ankle Joint, Yavuz Yildiz, Ufuk Şeki̇r, Bülent Hazneci̇, Fati̇h Örs, Tolga Saka, Taner Aydin

Turkish Journal of Medical Sciences

Aim: In contrast to the one-sided evaluation methods used in the past, combining multiple tests allows one to obtain a global assessment of the ankle joint. Materials and Methods: Twenty healthy male volunteers participated in this study. One component of the test battery included five different functional ability tests, which included: single limb hopping course, one-legged and triple-legged hop for distance, and six-meter (6-m) and cross 6-m hop for time. Ankle joint position sense and one leg standing test were used for proprioceptive evaluation. Isokinetic strength of the ankle invertor and evertor muscles were evaluated at a velocity of 120°/sec. …

Recurrent Breast Abscess Caused By Corynebacterium Amycolatum And Rewiev Of The Literature, İsmet Özaydin, Mustafa Yildirim, İdri̇s Şahi̇n, Sami̇ Doğan

Turkish Journal of Medical Sciences

Corynebacterium species are an uncommon cause of breast abscess, and Corynebacterium amycolatum is rarely described in the literature. In the present case, we report recurrent breast abscess caused by C. amycolatum in a 39-year-old patient with normal immune function. Pathological diagnosis was granulomatous mastitis. The patient was treated with incision and drainage and ampicillin-sulbactam treatment. To our knowledge, this is the second report of breast abscess caused by C. amycolatum.

Histopathological And Clinical Characteristics Of Secretory Carcinoma Of The Breast, Keri̇m Bora Yilmaz, Işin Pak, Can Atalay, Ci̇hangi̇r Özaslan

Turkish Journal of Medical Sciences

Secretory breast carcinoma is a rare form of invasive breast carcinoma constituting less than 1% of all breast cancer cases. Since insufficient data have been compiled about this rare tumor, it is important to report every case of secretory breast carcinoma in an effort to better understand the histopathological and clinical characteristics of this tumor and to contemplate the most appropriate therapeutic approach. In this report, two adult female patients over 50 years of age and a 14-year-old girl were reviewed with a detailed immunohistochemical work-up to define the clinical and molecular characteristics of secretory breast carcinoma.