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Articles 17011 - 17040 of 18049
Full-Text Articles in Entire DC Network
Determining The Health Beliefs And Breast Cancer Fear Levels Ofwomen Regarding Mammography, Fatma Ersi̇n, Fatma Gözükara, Peri̇han Polat, Gözde Erçeti̇n, Mehmet Ekrem Bozkurt
Determining The Health Beliefs And Breast Cancer Fear Levels Ofwomen Regarding Mammography, Fatma Ersi̇n, Fatma Gözükara, Peri̇han Polat, Gözde Erçeti̇n, Mehmet Ekrem Bozkurt
Turkish Journal of Medical Sciences
Background/aim: Women's fears and health beliefs impact their participation in early breast cancer diagnosis approaches. This study was conducted to determine the health beliefs and fear levels of women older than 50 regarding mammography. Materials and methods: A cross-sectional study was conducted in Turkey. The study cohort consisted of 300 women selected by cluster sampling who agreed to participate in the study. A health belief model scale and breast cancer fear scale were used in data collection. Descriptive statistics, t-test, chi-square test, and correlation analysis were used in the data analysis. Results: Participants had an age average of 59.88 ± …
Effects Of Melatonin And Theanine Administration On Pentylenetetrazole-Inducedseizures And Brain Tissue Oxidative Damage In Ovariectomized Rats, Shadi Choopankareh, Farzaneh Vafaee, Mohammad Naser Shafei, Hamid Reza Sadeghnia, Reza Salarinia, Leila Zarepoor, Mahmoud Hosseini
Effects Of Melatonin And Theanine Administration On Pentylenetetrazole-Inducedseizures And Brain Tissue Oxidative Damage In Ovariectomized Rats, Shadi Choopankareh, Farzaneh Vafaee, Mohammad Naser Shafei, Hamid Reza Sadeghnia, Reza Salarinia, Leila Zarepoor, Mahmoud Hosseini
Turkish Journal of Medical Sciences
Background/aim: The effects of coadministration of melatonin and theanine (Mel/Thea) on pentylenetetrazole (PTZ)-induced seizures and brain tissue oxidative damage were investigated in ovariectomized (OVX) and sham-operated rats. Materials and methods: The rats were divided into the following groups: 1) sham, 2) ovariectomized (OVX), 3) sham-PTZ, 4) OVX-PTZ, 5) sham-Mel/Thea-PTZ, and 6) OVX-Mel/Thea-PTZ. Groups 1-4 received saline, while groups 5 and 6 received a combination of Mel/Thea for 6 weeks. All animals except for those in groups 1 and 2 received a single injection of PTZ. Results: The OVX-PTZ group had higher generalized tonic-clonic seizure (GTCS) latency compared to the sham-PTZ …
Determination Of Apoptosis And Cell Cycle Modulators (P16, P21, P27, P53, Bcl-2,Bax, Bcl-Xl, And Cyclin D1) In Thyroid Follicular Carcinoma, Follicular Adenoma,And Adenomatous Nodules Via A Tissue Microarray Method, Peyker Temi̇z, Gi̇zem Akkaş, Nalan Neşe, Fazi̇let Uğur Duman, Cansu Karakaş, Yamaç Erhan
Determination Of Apoptosis And Cell Cycle Modulators (P16, P21, P27, P53, Bcl-2,Bax, Bcl-Xl, And Cyclin D1) In Thyroid Follicular Carcinoma, Follicular Adenoma,And Adenomatous Nodules Via A Tissue Microarray Method, Peyker Temi̇z, Gi̇zem Akkaş, Nalan Neşe, Fazi̇let Uğur Duman, Cansu Karakaş, Yamaç Erhan
Turkish Journal of Medical Sciences
Background/aim: To identify the role of gene products associated with apoptosis and cell cycle in the pathogenesis of thyroid follicular neoplasm. Materials and methods: Thirty follicular adenomas (FAs), 16 follicular carcinomas (FCs), and 20 adenomatous nodules (ANs) were investigated with immunohistochemical staining of p16, p21, p27, p53, Bcl-2, Bax, Bcl-xL, and cyclin D1 via a tissue microarray method. Results: Bcl-2 showed a significant difference between the benign groups (AN and FA) and the malignant group (FC). Bax was significantly higher in the FC group. p53 was lowest in the AN group and highest in the FC group with significant differences …
Smoking Cessation And The Effect Of Nicotine Dependence Onrelapse Rate In İzmir, Turkey, Özlem Pekel, Gül Ergör, Türkan Günay, Hakan Baydur, Beri̇l Choussein, Refi̇k Budak, Si̇nem Doğanay
Smoking Cessation And The Effect Of Nicotine Dependence Onrelapse Rate In İzmir, Turkey, Özlem Pekel, Gül Ergör, Türkan Günay, Hakan Baydur, Beri̇l Choussein, Refi̇k Budak, Si̇nem Doğanay
Turkish Journal of Medical Sciences
Background/aim: Smoking is the leading preventable cause of death in the world. There is growing evidence of the need for community-based programs on smoking cessation. The main purpose of this study is to establish the rate of smoking cessation and restarting in 1 year at the Balçova Smoking Cessation Center. Materials and methods: This is a prospective study with a study group of 359 individuals who quit smoking at the Balçova Smoking Cessation Center for at least 4 weeks between October 2009 and April 2010. The outcomes of the study were 1-year cessation rate and relapse rate. Individuals who reported …
Epidemiological And Clinical Characteristics And Management Of Oropharyngeal Tularemia Outbreak, Mustafa Önder Uzun, Kerametti̇n Yanik, Müge Erdem, Uğur Kostakoğlu, Gürdal Yilmaz, Yeli̇z Tanriverdi̇ Çayci
Epidemiological And Clinical Characteristics And Management Of Oropharyngeal Tularemia Outbreak, Mustafa Önder Uzun, Kerametti̇n Yanik, Müge Erdem, Uğur Kostakoğlu, Gürdal Yilmaz, Yeli̇z Tanriverdi̇ Çayci
Turkish Journal of Medical Sciences
Background/aim: The purpose of this study was to determine the epidemiological and clinical characteristics of patients diagnosed with tularemia and the effectiveness of the administered treatments. Materials and methods: Patients treated in our hospital between January 2009 and March 2011 and diagnosed with tularemia were evaluated retrospectively. Patients' epidemiological and clinical characteristics, administered treatments, and posttreatment findings were recorded on patient monitoring forms. Results: At anamnesis, 29% of patients used water from wells and 71% used water from the network supply; moreover, 48.4% had a history of contact with animals and 87.1% a history of lethargy. At physical examination, 96.8% …
Evaluation Of Patency Following Revision Technique Ofhigh-Velocity Arteriovenous Fistula, Ümi̇t Halici, Mehmet Ali̇ Kaygin, Özgür Dağ, Ahmet Aydin, Hüsnü Kami̇l Li̇mandal, Ümi̇t Arslan, Eyüp Serhat Çalik, Bi̇lgehan Erkut
Evaluation Of Patency Following Revision Technique Ofhigh-Velocity Arteriovenous Fistula, Ümi̇t Halici, Mehmet Ali̇ Kaygin, Özgür Dağ, Ahmet Aydin, Hüsnü Kami̇l Li̇mandal, Ümi̇t Arslan, Eyüp Serhat Çalik, Bi̇lgehan Erkut
Turkish Journal of Medical Sciences
Background/aim: The objective of this study is to report our experience with surgical revision of dialysis access-induced ischemia syndrome. Materials and methods: Between January 2005 and July 2013, 1254 patients underwent arteriovenous fistula operation, and 86 of them [53 males, mean age: 55 ± 25 (range: 25 to 75) years; 33 females, mean age: 50 ± 20 (range: 30 to 70) years] subsequently developed steal syndrome. These patients were treated with arterial pressure-controlled polytetrafluoroethylene banding or constriction with polypropylene suturing technique. Patients were followed in the outpatient clinic at regular intervals. Results: Symptoms were not relieved during the first 15 …
Value Of Prealbumin In Assessment Of Nutrition For Critically Ill Patients, Mehmet Ağilli, Şafak Eki̇nci̇
Value Of Prealbumin In Assessment Of Nutrition For Critically Ill Patients, Mehmet Ağilli, Şafak Eki̇nci̇
Turkish Journal of Medical Sciences
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Parp Inhibition Prevents Acetaminophen-Induced Liver Injury And Increases Survival Rate In Rats, Melahat Dönmez, Bülent Uysal, Yavuz Poyrazoğlu, Yeşi̇m Er Öztaş, Türker Türker, Ümi̇t Kaldirim, Ahmet Korkmaz
Parp Inhibition Prevents Acetaminophen-Induced Liver Injury And Increases Survival Rate In Rats, Melahat Dönmez, Bülent Uysal, Yavuz Poyrazoğlu, Yeşi̇m Er Öztaş, Türker Türker, Ümi̇t Kaldirim, Ahmet Korkmaz
Turkish Journal of Medical Sciences
Acetaminophen (APAP) overdose results in severe liver damage that may develop into acute liver failure. Recent studies have demonstrated that inhibition of poly(ADP-ribose) polymerase (PARP) decreases tissue necrosis and inflammation. We evaluated the efficacy of 3-aminobenzamide (3-AB), a PARP inhibitor, in a rodent model of APAP-induced hepatotoxicity. Materials and methods: Twenty-four Sprague-Dawley rats were divided equally into 3 experimental groups: sham group, APAP group, and APAP + 3-AB group. In the experimental treatment groups APAP was administered orally at 1 g/kg and, in the APAP + 3-AB group, 3-AB was administered intraperitoneally at a dose of 20 mg/kg exactly 1 …
An In Vitro And In Vivo Investigation Of The Cytotoxic Effects Of Caffeic Acid (3,4-Dihydroxycinnamic Acid) Phenethyl Ester And Bortezomib In Multiple Myeloma Cells, Ertan Altayli, Özgür Koru, Önder Öngürü, Tayfun İde, Cengi̇zhan Açikel, Meral Sarper, Mualla Pinar Elçi̇, Rahşan Ilikçi Sağkan, Erhan Astarci, Duran Tok, Sali̇m Özenç, Ali̇ Uğur Ural, Feri̇t Avcu
An In Vitro And In Vivo Investigation Of The Cytotoxic Effects Of Caffeic Acid (3,4-Dihydroxycinnamic Acid) Phenethyl Ester And Bortezomib In Multiple Myeloma Cells, Ertan Altayli, Özgür Koru, Önder Öngürü, Tayfun İde, Cengi̇zhan Açikel, Meral Sarper, Mualla Pinar Elçi̇, Rahşan Ilikçi Sağkan, Erhan Astarci, Duran Tok, Sali̇m Özenç, Ali̇ Uğur Ural, Feri̇t Avcu
Turkish Journal of Medical Sciences
In this study, the in vitro and in vivo effectiveness of caffeic acid (3,4-dihydroxycinnamic acid) phenethyl ester (CAPE) in combination with bortezomib, a proteasome inhibitor, was explored in multiple myeloma (MM) cells. Materials and methods: The cytotoxic effects of CAPE and bortezomib were determined by XTT cell proliferation assay. Apoptosis levels were analyzed with annexin V-fluorescein isothiocyanate, nuclear factor kappa beta (NF-\kappaB) was analyzed with electrophoretic mobility-shift assay, and interleukin (IL)-6 levels were analyzed with enzyme-linked immunosorbent assay to evaluate CAPE's mechanism of action. To investigate the in vivo effectiveness of CAPE and bortezomib, an experimental plasmacytoma model was induced …
Investigation Of West Nile Virus Among Healthy Blood Donors In The Western Part Of Turkey, Servet Uluer Bi̇çeroğlu, Ersi̇n Karatayli, Arzu Bayram, Ajda Turhan, Aysu Deği̇rmenci̇, Yeşi̇m Aydinok, Abdurrahman Mi̇that Bozdayi, Şazi̇ye Rüçhan Sertöz
Investigation Of West Nile Virus Among Healthy Blood Donors In The Western Part Of Turkey, Servet Uluer Bi̇çeroğlu, Ersi̇n Karatayli, Arzu Bayram, Ajda Turhan, Aysu Deği̇rmenci̇, Yeşi̇m Aydinok, Abdurrahman Mi̇that Bozdayi, Şazi̇ye Rüçhan Sertöz
Turkish Journal of Medical Sciences
The West Nile virus (WNV) is a mosquito-borne flavivirus causing different forms of infection among humans, varying from asymptomatic illness to fetal central nervous system infection. Turkey lies within an endemic region for WNV. Transfusion of infected blood products is another well-documented major route of transmission. The aim of our study was to investigate the presence of WNV viremia among a healthy donor population from the western part of the country. Materials and methods: A total of 438 healthy volunteer blood donors were included in the study. The presence of WNV RNA was investigated by quantitative real-time reverse-transcriptase polymerase chain …
Efficacy Of Entecavir Treatment Among Chronic Hepatitis B Nucleos(T)Ide-Naïve And -Experienced Patients, Kadi̇r Çağatay Bi̇çer, Alpay Ari, Vecdi̇ Evren Genç, Si̇bel Özsu Caymaz, Meltem Avci, Fatma Bal
Efficacy Of Entecavir Treatment Among Chronic Hepatitis B Nucleos(T)Ide-Naïve And -Experienced Patients, Kadi̇r Çağatay Bi̇çer, Alpay Ari, Vecdi̇ Evren Genç, Si̇bel Özsu Caymaz, Meltem Avci, Fatma Bal
Turkish Journal of Medical Sciences
To evaluate the efficacy of entecavir (ETV) among chronic hepatitis B (CHB) nucleos(t)ide-naïve and -experienced patients in clinical practice. Materials and methods: In this retrospective study 85 CHB patients who had been receiving ETV and who attended our clinic since 2007 were included. Fifty patients were nucleos(t)ide analogue (NA)-naïve. Factors including sex, positive HBeAg, baseline HBV DNA level, baseline alanine aminotransferase level, and prior lamivudine (LAM) resistance were evaluated in terms of their predictive role in treatment response, which was defined as a serum HBV DNA decrease of
A New Utilization Area For Hyperbaric Oxygen? Improving Quality Of Stored Blood, Hakan Ay, Ramazan Yüksel, Kemal Şi̇mşek, Turgut Topal, Özgür Yeşi̇lyurt, Şükrü Öter, Ahmet Korkmaz, Mehmet Özler, Bülent Uysal, Hali̇l Yaman, Orhan Bedi̇r, Hayati̇ Bi̇lgi̇ç
A New Utilization Area For Hyperbaric Oxygen? Improving Quality Of Stored Blood, Hakan Ay, Ramazan Yüksel, Kemal Şi̇mşek, Turgut Topal, Özgür Yeşi̇lyurt, Şükrü Öter, Ahmet Korkmaz, Mehmet Özler, Bülent Uysal, Hali̇l Yaman, Orhan Bedi̇r, Hayati̇ Bi̇lgi̇ç
Turkish Journal of Medical Sciences
Since blood bags have the ability for diffusion of gases, we investigated whether hyperbaric oxygen (HBO) exposure affects several vital parameters of stored blood. Materials and methods: Bloods obtained from the same persons were used as both control and HBO groups and stored in pediatric bags with citrate-phosphate-dextrose solution. HBO administration was performed at 2.5 atm for 90 min, started 1 day after blood collection and repeated every 2 days for a total of 10 times. The study was terminated on the 21st day. Complete blood count, glucose, pH, and osmotic fragility values were measured every week. Results: Glucose and …
The Protective Effect Of Syringic Acid On Ischemia Injury In Rat Brain, Mustafa Güven, Adem Bozkurt Aras, Naci̇ Topaloğlu, Adi̇le Özkan, Hali̇l Murat Şen, Yildiray Kalkan, Ali̇ Okuyucu, Ayla Akbal, Ferhat Gökmen, Murat Çoşar
The Protective Effect Of Syringic Acid On Ischemia Injury In Rat Brain, Mustafa Güven, Adem Bozkurt Aras, Naci̇ Topaloğlu, Adi̇le Özkan, Hali̇l Murat Şen, Yildiray Kalkan, Ali̇ Okuyucu, Ayla Akbal, Ferhat Gökmen, Murat Çoşar
Turkish Journal of Medical Sciences
Brain ischemia and treatment are important topics in neurological science. Free oxygen radicals and inflammation formed after ischemia are accepted as the most significant causes of damage. Currently there are studies on many chemopreventive agents to prevent cerebral ischemia damage. Our aim is to research the preventive effect of the active ingredient in syringic acid, previously unstudied, on oxidative damage in cerebral ischemia. Materials and methods: The rats were randomly divided into 4 groups: control group (no medication or surgical procedure), sham group (artery occlusion), artery occlusion + syringic acid group sacrificed at 6 h, and artery occlusion + syringic …
Characterization Of Stard4 And Stard6 Proteins In Human Ovarian Tissue And Human Granulosa Cells And Cloning Of Human Stard4 Transcripts, Aisha Shaaban
Theses and Dissertations
Progesterone is essential hormone for pregnancy, which is produced by the human corpus luteum in early pregnancy until the placenta assumes this function. Transport of the cholesterol from the outer to the inner mitochondrial membrane is the rate limiting step for the de novo synthesis of pregnenolone (the precursor to progesterone), a process mediated by STARD1. STARD1 contains a C-terminal lipid binding domain which binds cholesterol and an N-terminal domain targeting STARD1 to the mitochondrial membrane. Unlike STARD1, STARD4 and STARD6 proteins lack a mitochondrial targeting sequence; however, they can bind cholesterol and increase steroidogenesis in model systems. In this …
Using The Symmetry Of False Matches To Solve The Correspondence Problem, Cherlyn J. Ng, Bart Farell
Using The Symmetry Of False Matches To Solve The Correspondence Problem, Cherlyn J. Ng, Bart Farell
Biomedical and Chemical Engineering - All Scholarship
Veridical stereoscopic depth depends on matching corresponding image points. This requires solving the stereo correspondence problem: how are true matches distinguished from false ones? Conventional algorithms select true matches on the basis of feature detection [what do you mean by ‘feature detection’ here? Is there some more specific term?] and adherence to natural statistics. They reject false matches as noise. We propose here an alternative that uses the signals present in false matches to delineate the true solution. When visualized in a Keplerian array, binocular matches are symmetrically reflected about an axis that is a potential solution. Properties such as …
The Effects Of Curcumin On The Expression Of P53 And Bcl-2 Oncoproteins On The Human Breast Carcinoma Cell Line Mda-Mb 468, Angelin S. Shajan
The Effects Of Curcumin On The Expression Of P53 And Bcl-2 Oncoproteins On The Human Breast Carcinoma Cell Line Mda-Mb 468, Angelin S. Shajan
Theses and Dissertations
We studied the effects of curcumin on the proliferation and viability of MDA-MB-468 breast cancer cells and its effects on the expression ofBcl-2 and p53 proteins in these cells. Based on previous studies, we predicted a dose-dependent increase in p53 (tumor suppressor) expression, and a decrease in Bcl-2 (anti-apoptotic oncoprotein) expression. Briefly, MDA-MB468 cells were seeded into 12-well plates at 2.0 * 104 cells/well and allowed to grow for 72 hrs. Cells were treated with curcumin at 0, 25, 50 and 100 pM in triplicate at time zero and cultured for another 24 hours. All data were obtained using a …
Overexpression Of Human Cu/Zn Superoxide Dismutase In Mice; The Effect Of Increase Superoxide Scavenging On Autonomic Control Of The Heart., Jeffrey Hatcher
Overexpression Of Human Cu/Zn Superoxide Dismutase In Mice; The Effect Of Increase Superoxide Scavenging On Autonomic Control Of The Heart., Jeffrey Hatcher
Electronic Theses and Dissertations
Dysregulation of the autonomic cardiovascular control is a complication of diseases including diabetes, hypertension, sleep apnea, and aging. A common factor in these conditions is an increase in reactive oxygen species (ROS) in neural, cardiac, and endothelial tissues. Cu/Zn superoxide dismutase (SOD1) is an intracellular anti-oxidant enzyme that catalyzes dismutation of the superoxide anion (O2.-) to hydrogen peroxide (H2O2). Expression and function of this enzyme are diminished in pathologies that impair cardiovascular autonomic control. This study employed mice overexpressing a transgene for human SOD1 (hSOD1) to determine if its overexpression would alter autonomic regulation of BP, HR, and BRS in …
Distribution Of Viral Genotypes And Extrahepatic Manifestations In Patients With Chronic Hepatitis C In Eastern Turkey, Si̇bel İba Yilmaz, Serpi̇l Erol, Ahmet Özbek, Mehmet Parlak
Distribution Of Viral Genotypes And Extrahepatic Manifestations In Patients With Chronic Hepatitis C In Eastern Turkey, Si̇bel İba Yilmaz, Serpi̇l Erol, Ahmet Özbek, Mehmet Parlak
Turkish Journal of Medical Sciences
To investigate the distribution of viral genotypes, the extrahepatic manifestations, and the relationship between genotypes and extrahepatic manifestations in patients with chronic hepatitis C. Materials and methods: The study included 62 treatment-naive patients with chronic hepatitis C infection. Genotype determination was performed by DNA sequencing analysis. To investigate extrahepatic manifestations, the patients' data, recorded prospectively during the pretreatment period, were analyzed. Results: Genotype determination was successful in 74.2% of the cases. All patients were infected with hepatitis C virus (HCV) genotype 1b. At least 1 extrahepatic manifestation was identified in 37.1% of the patients. The most frequent clinical manifestations were …
A Molecular Epidemiological Investigation Of Multistate Outbreaks Of Salmonella Enteritidis From Clinical And Environmental Samples In Turkey, 2000-2010, Sümeyra Acar, Belkis Levent, Ekrem Atalan
A Molecular Epidemiological Investigation Of Multistate Outbreaks Of Salmonella Enteritidis From Clinical And Environmental Samples In Turkey, 2000-2010, Sümeyra Acar, Belkis Levent, Ekrem Atalan
Turkish Journal of Medical Sciences
To analyze interrelated Salmonella Enteritidis strains isolated in Turkey. Fifty-five S. Enteritidis surveillance strains were isolated from human feces and environmental samples from different regions in Turkey between 2000 and 2010. Materials and methods: Clinical isolates were selected from different outbreaks in the Turkish National Reference Laboratory. All isolates were submitted to antimicrobial susceptibility test, plasmid profile analysis, and XbaI-digested pulsed-field gel electrophoresis. Results: The strains were scanned against 20 antibiotics and for 3 of them (amikacin, ciprofloxacin, gentamicin), all strains were found to be sensitive. Five isolates had no plasmid. Most of test strains carried the 57-kb plasmid in …
Effect Of Keratinocyte Growth Factor On Growth And Transdifferentiationof Primary Alveolar Epithelial Type Ii Cells, Xiuxiang Liu, Zhichun Feng, Chunmei Tian, Xiangyong Kong, Yumei Wu, Changjun Lv
Effect Of Keratinocyte Growth Factor On Growth And Transdifferentiationof Primary Alveolar Epithelial Type Ii Cells, Xiuxiang Liu, Zhichun Feng, Chunmei Tian, Xiangyong Kong, Yumei Wu, Changjun Lv
Turkish Journal of Medical Sciences
Background/aim: To investigate the effects of keratinocyte growth factor (KGF) on the growth and transdifferentiation of primary alveolar epithelial type II cells (AECIIs). Materials and methods: The number of primary AECIIs, their viability, and cell cycle and apoptosis were studied under KGF treatment using a hemocytometer, trypan blue exclusion, and flow cytometry, respectively. Positive expressions of surfactant protein C (SP-C), aquaporin 5 (AQP5), and thyroid transcription factor 1(TTF-1) were examined with indirect immunofluorescence; mRNA levels of SP-C, AQP5, and TTF-1 were determined by polymerase chain reaction. Results: In response to KGF treatment, cell numbers were significantly increased, more cells were …
Hemodynamic Effects Of Atrial Natriuretic Peptide In Ischemia-Reperfusioninjury That Occurs After Exercise, Selma Arzu Vardar, Orki̇de Palabiyik, Ruhan Deni̇z Topuz, Eli̇f Ezgi̇ Gürel, Semra Çalişkan, Serap Topcu Özen, Necdet Süt, Çeti̇n Hakan Karadağ
Hemodynamic Effects Of Atrial Natriuretic Peptide In Ischemia-Reperfusioninjury That Occurs After Exercise, Selma Arzu Vardar, Orki̇de Palabiyik, Ruhan Deni̇z Topuz, Eli̇f Ezgi̇ Gürel, Semra Çalişkan, Serap Topcu Özen, Necdet Süt, Çeti̇n Hakan Karadağ
Turkish Journal of Medical Sciences
Atrial natriuretic peptide (ANP) is known as a protective agent against ischemia-reperfusion injury for cardiomyocytes. We compared the hemodynamic effects of ANP and isatin, which is known as an ANP receptor blocker, in ischemia followed by reperfusion in exercised rat hearts with nonexercised ones. Materials and methods: Isolated hearts were perfused in 4 exercised (E) groups after a running protocol for 5 days and 4 nonexercised (NE) groups. In the first protocol, ANP was added to the perfusion solution before ischemia in an E and NE group. In the second protocol, different doses of isatin (0.1, 10, 100 µM/L) were …
Evaluation Of Children Presenting To The Emergency Room After Electrical Injury, Aslihan Arasli Yilmaz, Ali̇ Osman Köksal, Osman Özdemi̇r, Mehtap Acar, Gülten Küçükkonyali, Yasemi̇n İnan, Si̇bel Çeli̇k, Mi̇ne Güveloğlu, Nesi̇be Andiran, Saci̇t Günbey
Evaluation Of Children Presenting To The Emergency Room After Electrical Injury, Aslihan Arasli Yilmaz, Ali̇ Osman Köksal, Osman Özdemi̇r, Mehtap Acar, Gülten Küçükkonyali, Yasemi̇n İnan, Si̇bel Çeli̇k, Mi̇ne Güveloğlu, Nesi̇be Andiran, Saci̇t Günbey
Turkish Journal of Medical Sciences
Background/aim: To evaluate children who presented to the Pediatric Emergency Department with electrical injury and to discuss the follow-up of these cases and potential precautions that can be taken. Materials and methods: A total of 36 patients presented to the Pediatric Emergency Department with electrical injury between May 2010 and May 2013, and these cases were investigated retrospectively. The patients? age and sex, location and form of exposure to electric current, seasonal distribution, length of hospital stay, musculoskeletal and cardiovascular system complications, renal damage, and treatments were recorded. Results: The majority of the patients were exposed to low-voltage electrical current …
The Relationship Between Hepatitis Serology Of Ambulance Attendants Andduration Of Education, Ertuğrul Güçlü, Azi̇z Öğütlü, Oğuz Karabay
The Relationship Between Hepatitis Serology Of Ambulance Attendants Andduration Of Education, Ertuğrul Güçlü, Azi̇z Öğütlü, Oğuz Karabay
Turkish Journal of Medical Sciences
Background/aim: Healthcare workers (HCWs) run the risk of hepatitis B virus (HBV) infection. Studies investigating the HBV and hepatitis C virus (HCV) serology of HCWs have been generally conducted in secondary or tertiary hospitals. In this study we aimed to determine the relationships between education level and HBV and HCV serology and HBV vaccination status of ambulance attendants. Materials and methods: The data of this study were obtained by retrospective review of ambulance personnel files in Sakarya Province, Turkey. Results: Out of 314 ambulance attendants, 216 (68.7%; 78 males, 138 females) were enrolled in this study. The mean length of …
Malondialdehyde And Nitric Oxide Levels And Catalase, Superoxide Dismutase, And Glutathione Peroxidase Levels In Maternal Blood During Different Trimesters Ofpregnancy And In The Cord Blood Of Newborns, Sevda Yüksel, Ayşe Arzu Yi̇ği̇t
Malondialdehyde And Nitric Oxide Levels And Catalase, Superoxide Dismutase, And Glutathione Peroxidase Levels In Maternal Blood During Different Trimesters Ofpregnancy And In The Cord Blood Of Newborns, Sevda Yüksel, Ayşe Arzu Yi̇ği̇t
Turkish Journal of Medical Sciences
Background/aim: To determine whether levels of malondialdehyde (MDA), nitric oxide (NO), superoxide dismutase (SOD), glutathione peroxidase (GPx), and catalase (CAT) change during the 3 trimesters of pregnancy, and to compare the third trimester of pregnancy with newborn cord blood in respect to the levels of MDA, NO, and antioxidant enzymes. Materials and methods: Maternal blood samples were collected at 9?13, 22?26, and 36?40 weeks of gestation. Cord blood was collected at the time of delivery. Results: NO levels and GPx activity were higher in the second and third trimesters than in the first trimester. MDA level was lower in the …
Characterization Of Hcv Genotype 4d Infections In Kayseri, Turkey*, Tuba Kayman, Ceylan Polat, Gül Ergör, Yusuf Hakan Abacioğlu
Characterization Of Hcv Genotype 4d Infections In Kayseri, Turkey*, Tuba Kayman, Ceylan Polat, Gül Ergör, Yusuf Hakan Abacioğlu
Turkish Journal of Medical Sciences
Background/aim: The frequency of genotype 4 hepatitis C virus (HCV) infections is significantly higher in Kayseri compared to other provinces in Turkey. We aimed to characterize genotype 4 infections in Kayseri by analyzing the demographic and laboratory data of 218 HCV RNA-positive, treatment-naive patients admitted to the Kayseri Training and Research Hospital in 2010 and 2011. Materials and methods: The distributions of sex, age, and viral loads of these patients with respect to HCV genotypes were analyzed. We also characterized the type 4 sequences at the subtype level. Randomly selected sera from 32 of the 72 genotype 4 patients from …
Comparison Of The Contamination Rates Of Culture Media Used For Isolation And Identification Of Dermatophytes, Ramazan Gümral, Ayli̇n Döğen, Mehmet Maci̇t İlki̇t
Comparison Of The Contamination Rates Of Culture Media Used For Isolation And Identification Of Dermatophytes, Ramazan Gümral, Ayli̇n Döğen, Mehmet Maci̇t İlki̇t
Turkish Journal of Medical Sciences
Background/aim: Mycological media that promote spore production are essential for the diagnosis of dermatophytosis. However, these culture media frequently become contaminated by multiple fungal or bacterial species during culture. The aim of this study was to compare the contamination rates of 6 culture media used for the isolation and identification of dermatophytes, including Borelli's lactritmel agar (BLA), brain-heart infusion agar (BHIA), Lowenstein-Jensen agar (LJA), malt extract agar (MEA), potato dextrose agar (PDA), and Sabouraud glucose agar (SGA). Materials and methods: Agar plates were inoculated with 43 well-characterized dermatophyte strains, belonging to the genera Arthroderma, Epidermophyton, Microsporum, or Trichophyton. The agar …
Elevated Serum Matrix Metalloproteinase-2 And -9 And Their Correlationswith Severity Of Disease In Patients With Community-Acquired Pneumonia, Haci Ahmet Bi̇rcan, Müni̇re Çakir, İlkay Yilmazer Kapulu, Recep Sütcü, Selçuk Kaya, Önder Öztürk
Elevated Serum Matrix Metalloproteinase-2 And -9 And Their Correlationswith Severity Of Disease In Patients With Community-Acquired Pneumonia, Haci Ahmet Bi̇rcan, Müni̇re Çakir, İlkay Yilmazer Kapulu, Recep Sütcü, Selçuk Kaya, Önder Öztürk
Turkish Journal of Medical Sciences
Background/aim: To determine the role of matrix metalloproteinases (MMPs) and their relationship with the clinical course of community-acquired pneumonia (CAP). Materials and methods: Sixty-two consecutively hospitalized patients with CAP were enrolled and their pneumonia severity index (PSI), time to clinical stability (TCS), treatment response, and complications were recorded. The pre- and posttreatment serum concentrations of MMPs and their inhibitors were analyzed by ELISA. The activities of MMPs were evaluated by gelatin zymography. Results: MMP-2 and -9 serum levels and their activities were higher in CAP patients than controls (P < 0.001 and P < 0.001, respectively). Low-risk patients had lower levels of MMP-2 and TIMP-1 than high-risk patients (P = 0.044, P = 0.001, respectively). Pretreatment serum TIMP-1 level was higher in patients with TCS of >3 days (P = 0.004) and was correlated with oxygenation and …
Fetal Health Locus Of Control In A Sample Of Pregnant Turkish Women, Sevgi̇ Özcan, Veli̇ Duyan
Fetal Health Locus Of Control In A Sample Of Pregnant Turkish Women, Sevgi̇ Özcan, Veli̇ Duyan
Turkish Journal of Medical Sciences
Background/aim: To examine the relationship between sociodemographic and pregnancy features and fetal health locus of control (FHLC) in a sample of pregnant Turkish women. Materials and methods: The study was conducted with 256 pregnant women. Data were collected by demographic questionnaire and the FHLC Scale consisting of 3 components: 1) Internality Scale (FHLC-I), 2) Powerful Others Scale (FHLC-P), and 3) Chances Scale (FHLC-C). Results: The age of marriage was found to have a positive relation with FHLC-I (r = 0.141) and a negative relation with FHLC-C (r = -0.145) (P < 0.05). The age of first pregnancy was found to have a positive relation with FHLC-I (r = 0.127). Those who have a low educational level (r = -0.258) and income (r = -0.149), who are unemployed (r = -2.839), whose number of pregnancies is high (r = 0.152), who get pregnant unplanned (r = 3.839), and who come to their first prenatal examination late (r = -0.142) have a significantly high score of FHLC-C (P
Distribution And Antifungal Resistance Of Candida Speciesisolated From Intensive Care Units, Pinar Korkmaz, Yeşi̇m Alpay, Fi̇gen Çevi̇k, Nevi̇l Aykin, Ayşe Koygun, Hakki Mustafa Güldüren
Distribution And Antifungal Resistance Of Candida Speciesisolated From Intensive Care Units, Pinar Korkmaz, Yeşi̇m Alpay, Fi̇gen Çevi̇k, Nevi̇l Aykin, Ayşe Koygun, Hakki Mustafa Güldüren
Turkish Journal of Medical Sciences
No abstract provided.
Myelodysplastic Features And Cellular Senescence In Autoimmune Disorders: A Pilot Study On Patients With Collagen Tissue Disorders And Immune Thrombocytopenic Purpura, Lale Olcay, Deni̇z Bi̇llur, Esra Erdemli̇, Sidika Esra Baskin, Havva Fatma Balci, Sevgi̇ Yetgi̇n
Myelodysplastic Features And Cellular Senescence In Autoimmune Disorders: A Pilot Study On Patients With Collagen Tissue Disorders And Immune Thrombocytopenic Purpura, Lale Olcay, Deni̇z Bi̇llur, Esra Erdemli̇, Sidika Esra Baskin, Havva Fatma Balci, Sevgi̇ Yetgi̇n
Turkish Journal of Medical Sciences
No abstract provided.