Digital Commons Network^™

In Silico Investigations Of Class Ii Trans Activator (Ciita): Its Plausible Implications In Neuroinflammation And Neurological Disorders, Kishore N

Theses and Dissertations

Inflammation plays a significant role in maintaining homeostasis. Neuroinflammation is a chronic inflammatory response in the central nervous system (CNS), leading to brain or spinal cord dysfunction. To promote mental health, it is crucial to understand the regulation of neuroinflammation. Class II transactivator (CIITA) is a master-regulator of the major histocompatibility complex II (MHCII).

Modulation of CIITA has been suggested as a promising intervention for inflammatory conditions, including neurological disorders. However, there is limited knowledge about the role of CIITA and its interactors in inflammation. This study aimed to understand the role of CIITA in neuroinflammation and neurological disorders using …

3d Bioprinting On Electrospun Nanofibrous Scaffolds To Fabricate Myocardial Patches, Muthu Parkkavi S

Theses and Dissertations

Tissue-engineered three-dimensional (3D) myocardial patches offer superior and innovative treatment strategy for myocardial infarction (MI). Among the various scaffold fabrication techniques, electrospinning and 3D bioprinting have received great attention due to their ability to recreate native cardiac tissue mimetic characteristics. Despite several advantages, electrospun nanofibers have limitations in cell delivery due to random cell seeding, while bioprinting faces challenges in creating hydrogel constructs with ideal mechanical properties capable of supporting cardiac contraction/relaxation cycle. Hence in this work, hybrid myocardial patches were developed by converging electrospinning and bioprinting techniques.

Electrospinning of PLCL:PEOz (B73, 7:3 blend of poly-L-lactide-co-ε-caprolactone (PLCL) and polyethyl oxazoline …

Effect Of Osmolytes On The Interplay Of Water Protein And Dna In Ecori Dna Recognition Using Molecular Dynamics Simulations, Aathithya D

Theses and Dissertations

EcoRI is a type II restriction endonuclease that has been widely used as a model system to study protein-DNA interaction owing to its high degree of specificity. This enzyme does not recognize even a single basepair change in its recognition sequence, (GAATTC)2, under normal conditions. However, in the presence of osmolytes, such as glycerol and DMSO, the specificity of EcoRI is slightly relaxed and recognizes sequences that differ from its cognate sequence in the first basepair position. This relaxed specificity has been attributed to the dehydration of the EcoRI-DNA which presumably results in tighter complex formation and subsequent catalysis. However, …

Biogenic Calcite Precipitation For Coastal Sand Stabilization: A Synergistic Approach Using Marine Bacteria And Natural Fibers, Aparna Gs

Theses and Dissertations

Coastal erosion, driven by natural forces such as waves, tides, winds, and currents and further intensified by anthropogenic activities like urbanization, climate change, and coastal infrastructure development, poses a significant threat to shoreline stability. Conventional erosion control methods, including jetties, embankments, and artificial reefs, often face limitations in sustainability and effectiveness. In this context, microbially induced calcite precipitation (MICP) has emerged as a promising ecofriendly solution for ground stabilization.

The present study investigates the potential of an indigenous ureolytic marine bacterium, Bacillus sp. N₉, isolated from the coastal sediments of Nagapattinam, Tamil Nadu, for coastal sand stabilization. The strain was …

Fabrication Of Protein-Based Nanomicelle Against Inflamed Synoviocytes In Rheumatoid Arthritis, Madhumithra Thangadurai

Theses and Dissertations

Rheumatoid arthritis (RA) is a chronic autoimmune disease marked by persistent synovial inflammation, progressive cartilage and bone destruction, and systemic complications. 1% of the global population are affected by RA, when their immune system targets synovial tissues, leading to joint pain, swelling, and functional disability. Standard treatments, such as disease-modifying antirheumatic drugs (DMARDs) like methotrexate (MTX), are limited by systemic toxicity and inconsistent patient responses, highlighting the need for improved therapies. This research work explores protein-glycosaminoglycan nanomicelles engineered using Zein with Chondroitin or carboxymethylated Dextran Sulfate as targeted drug delivery vehicles for RA.

MTX was encapsulated within these nanomicelles to …

Genomic Surveillance Of Indian Klebsiella Pneumoniae And Exploration Of Resistance Inhibitors, Abhirami Ks Ms

Theses and Dissertations

Klebsiella pneumoniae is an important ESKAPE pathogen that causes life threatening infections. The strains exhibiting multidrug-resistance (MDR) and hypervirulence are the priority pathogens for which immediate treatment and dissemination prevention strategies are required. To address this, genome profiling was performed to understand the AMR patterns, role of episomes, phages, virulence determinants and its association with sequence types.

The study includes 267 publicly available Indian K. pneumoniae genomes over a period of ten years and four sequenced isolates. Whole genome analysis revealed the widespread presence of diverse β-lactamase genes, with β-lactam resistance being predominant. Genes such as blaCTX-M-15, blaTEM-1B and blaOXA-232 …

Differences In Fitness Between Cadet And General Population Firefighter Academy Recruits, Scott D. Brau, David Cornell, Benjamin J. Mendelson, Rudi A. Marciniak, Kyle Ebersole

International Journal of Exercise Science

International Journal of Exercise Science 18(8): 774-793, 2025. This longitudinal study explored entry route- and age-related fitness differences between cadet (CR) and general population (GR) firefighter recruits. Fitness data were collected from eight separate firefighter recruit academy cohorts (N = 317; 122 CR, 195 GR; 27.17 ± 7.58 yrs, 177.30 ± 8.72 cm, 88.65 ± 17.78 kg). In the first week of the academy, recruits completed an assessment battery including: body composition via skinfold measures to estimate body fat (BF, %) and fat-free mass (FFM, kg); aerobic fitness (VO_2peak, mL· kg^-1· min^-1) and …

Periodic Evaluations Indicate Increased Effectiveness Of Oregon Master Woodland Manager Volunteer Program, Alicia Christiansen, Lauren Grand, Norma Kline, Tiffany Hopkins

Journal of Extension

The Oregon State University Extension Service Master Woodland Manager (MWM) volunteer program trains landowners in core forestry and natural resource topics. Landowners participate in the MWM program to increase their forest management knowledge, improve their own management practices, and prepare them to volunteer in their community (Bowers, 2000). We surveyed MWM volunteers to understand the effectiveness of the program and what barriers exist to volunteering. Volunteers find the program to be increasingly adequate for personal management and answering questions, but time continues to be the biggest barrier for completing required volunteer hours.

Small Meat Processor Needs Are Similar Across Region, Jordan C. Wicks, Alexis Wivell, Thomas Archibald, David Gerrard

Journal of Extension

This needs-based assessment provides insight into the challenges of small meat processors in two regions of the US. On-line surveys were provided to processors and despite regional differences, data show approximately 70% of processors in each state find retention of skilled labor the greatest challenge in maintaining current levels of operation and impede future growth. These findings suggest educational and certification programing may help improve small processor viability and mitigate local food security concerns. Given the disparity in animal production and livestock availability between these diverse states but similarity in responses, we posit this information is translatable across the US.

Partial Budgets Quantify Economic Outcomes Of Soil Health Management For Farmers, Jessica A. Kelton, W. Archie Flanders, Emily P. Ball, Dianna K. Bagnall, C. Wayne Honeycutt

Journal of Extension

Implementation of soil health management systems, such as reduced tillage and cover cropping, can reduce soil erosion, increase water infiltration, and improve soil productivity. Adoption of these practices can also improve net farm income, but effects vary based on region, commodity, and production methods. A partial budget analysis approach was used to evaluate impacts of adoption of soil health management systems on profitability from a regional, on-farm, perspective. The approach provides farmers with a resource to support decisions when considering the adoption of soil health management systems.

Economic Analysis Of Stockers Grazing Botanically Diverse Summer Annual Pasture, Kelly M. Mercier, Christopher D. Teutsch, S. Ray Smith, Kenneth H. Burdine, Eric S. Vanzant, Edwin L. Ritchey

Journal of Extension

Economic analyses were performed to determine the feasibility of retaining weaned fall-born calves on summer annual pastures (a monoculture, a 3-species mixture, or a 12-species mixture). Average daily gain was reduced by 0.3 lbs/day in calves grazing the complex mixture in two out of three years. Enterprise budgeting illustrated that retaining calves on summer annual forages was not economical. Two-way net return tables indicated that this scenario would only be profitable when cattle prices are high and pasture establishment costs are low. Extension educators should be sure to emphasize the economic risks when discussing these systems.

Facilitating Farmer-To-Farmer Elearning: An Evaluation Of Climate And Wildfires Online Courses In California, Natalia Pinzon, Caitlin Brimm

Journal of Extension

This study assesses the effectiveness of two online courses tailored for farmers and ranchers in California, with a particular focus on the role of farmer-to-farmer pedagogies. Utilizing live sessions, a social-learning platform, and multimedia content, we draw insights from engagement metrics, lesson and end-of-course survey evaluations, and course outcomes. Key findings highlight the pivotal role of peer interactions, featuring farmers and completion incentives. Based on the findings, we advocate for the integration of farmer-to-farmer education methods within online learning environments to cultivate regional learning networks, and promote the timely exchange and co-creation of agricultural knowledge amid environmental change.

Evaluation Of South Carolina’S Extension And Outreach Agents’ Knowledge Of Harmful Algal Bloom Management And The Impacts Of One-Day Training, George Strickland, Debabrata Sahoo, Michael Vassalos, Heather Nix, Sarah White

Journal of Extension

Harmful algal blooms (HABs) impact livestock producers. Most Extension agents have limited knowledge about HAB management. Our study goal was to assess agent readiness and training on HABs. We used data from in-person surveys of South Carolina (SC) Extension personnel. We examined how training influenced HAB knowledge using pre/post-tests. Training improved agent knowledge of HAB management, but water resource agents learned more. The results of this study can be used to identify Extension training shortfalls and drive policy to better prepare agents throughout the state. Further research should involve prioritizing additional extension topics and assessing knowledge in a similar manner.

Kdm2b Variants In The Cxxc Domain Impair Its Dna-Binding Ability And Cause A Distinct Neurodevelopmental Syndrome, Amber S E Van Oirsouw, Michael A Hadders, Martijn Koetsier, Edith D J Peters, Nurit Assia Batzir, Tahsin Stefan Barakat, Diana Baralle, Adelyn Beil, Marie-Noëlle Bonnet-Dupeyron, Philip M Boone, Arjan Bouman, Deanna Alexis Carere, Benjamin Cogne, Leslie Dunnington, Laura S Farach, Casie A Genetti, Bertrand Isidor, Louis Januel, Aakash Joshi, Nayana Lahiri, Kristen N Lee, Idit Maya, Meriel Mcentagart, Hope Northrup, Mathilde Pujalte, Kate Richardson, Susan Walker, Bobby P C Koeleman, Mariëlle Alders, Richard H Van Jaarsveld, Renske Oegema

Faculty, Staff and Student Publications

Rare variants affecting the epigenetic regulator KDM2B cause a recently delineated neurodevelopmental disorder. Interestingly, we previously identified both a general KDM2B-associated episignature and a subsignature specific to variants in the DNA-binding CxxC domain. In light of the existence of a distinct subsignature, we set out to determine if KDM2B CxxC variants are associated with a unique phenotype and disease mechanism. We recruited individuals with heterozygous CxxC variants and assessed the variants' effect on protein expression and DNA-binding ability. We analyzed clinical data from 19 individuals, including ten previously undescribed individuals with seven novel CxxC variants. The core phenotype of the …

Newly Diagnosed Acute Myeloid Leukemia In Unfit Patients: 2026 Treatment Algorithms, Naseema Gangat, Courtney D Dinardo

Faculty, Staff and Student Publications

Management paradigms for newly-diagnosed acute myeloid leukemia (ND-AML) in patients considered unfit to receive intensive chemotherapy have evolved with improved understanding of disease biology. In this setting, management requires clear delineation of goals of therapy that should include preservation of quality-of-life (QoL). Combination of venetoclax (Ven) and a hypomethylating agent (HMA) is the current standard-of-care in most circumstances with flexible options in regard to drug dose and duration of treatment as well as the addition (triplet combinations) or alternative use of targeted therapies, such as inhibitors of FLT3, IDH1, IDH2, or menin for patients with NPM1MUT …

Understanding Salt Stress In Watermelon: Impacts On Plant Performance, Adaptive Solutions, And Future Prospects, Sukhmanjot Kaur, Milena Maria Tomaz De Oliveira, Amita Kaundal

Plants, Soils and Climate Student Research

Soil salinity stress, intensified by extreme weather patterns, significantly threatens global watermelon [Citrullus lanatus (Thunb.) Matsum & Nakai] production. Watermelon, a moderately salt-sensitive crop, exhibits reduced germination, stunted growth, and impaired fruit yield and quality under saline conditions. As freshwater resources decline and agriculture’s dependency on irrigation leads to soil salinization, we need sustainable mitigation strategies for food security. Recent advances highlight the potential of using salt-tolerant rootstocks and breeding salt-resistant watermelon varieties as long-term genetic solutions for salinity. Conversely, agronomic interventions such as drip irrigation and soil amendments provide practical, short-term strategies to mitigate the impact of salt …

Associations Of Laboratory- And Field- Derived Measurements Of Critical Power With W’-Kinetics During 40-Km Cycling Time Trial Performances, Dewey Luke Wilkins, Robert W. Pettitt, Julie Taylor, Mark Kramer

International Journal of Exercise Science

International Journal of Exercise Science 18(8): 757-773, 2025. This study aimed to establish whether a laboratory (lab) based 3-minute all-out (3MT) protocol and a field-based 3MT protocol would yield similar peak power (P_max), critical power (CP), and curvature constant (W’) profiles and the implications of parameter estimation for informing a 40-km time trial (TT) performance. Nine competitive male cyclists (mean ± SD: age 36.5 ± 10.42 y, mass = 80.5 ± 10.6 kg, height 1.8 ± 0.1 m) completed two 3MTs on separate days, as well as a 40-km time trial. Both lab and field-based protocols evoked similar …

Using Vegetation Communities To Compare Natural And Constructed Wetlands In The Red River Basin In Texas And Louisiana, Kennedi K. Davis

Biology Theses

Wetland vegetation provides an abundance of ecosystem services such as water quality regulation, flood control, and it provides habitat space for fish, amphibians, and macroinvertebrates. Not only that, but these plants also act as excellent indicators of wetland conditions as dominant vegetation types are often used as biological criteria for classifying wetlands and other habitats (Cowardin and Golet, 1995). This project will assess the structure of vegetation communities to determine how they differ in constructed and natural wetlands within the Red River drainage basin to see if Agricultural Conservation Easement Program – Wetland Reserve Easement (ACEP-WRE) constructed wetlands are effective …

Variation In Phenotype, Genotype, And Somatic Diversity Among Asexual Schmidtea Mediterranea Planarians, S. Kershenbaum, Danielle Ireland, Ziad Sabry , '20, Christina Rabeler, Vir Shetty , '22, A. Aboobaker, Eva-Maria S. Collins

Biology Faculty Works

Most multicellular life reproduces sexually, utilizing a single-celled stage that acts as a genetic bottleneck. This bottleneck limits the evolution of selfish cell adaptations by ensuring all cells descend from a single progenitor. We investigated an obligately asexual strain of Schmidtea mediterranea planarians that reproduces by self-bisection and lacks a single-cell bottleneck. Using 2.5 yearlong data on planarian reproductive behavior combined with genotyping, we revealed two previously undescribed genetically distinct substrains within the CIW4 strain. One substrain showed reduced fitness, which correlated with substantial losses of heterozygosity and increased somatic diversity. By genotyping consecutive head offspring over multiple generations, we …

Advance S In The Generation And Transport Behavior Of Secondary Hazards From Food Packaging Sterilization, Mengjia Ren, Ye Liu, Jinpeng Wang, Shuang Bi

Journal of Food Science and Biotechnology

Food packaging sterilization is an important technical means to avoid the spread of SARS-CoV- 2 and the cross-contamination of foodborne viruses.However,the secondary hazards generated after sterilization are complex and have different characteristics,and a wide range of factors affect the formation of these hazards.The studies about the migration behavior of secondary hazards from packaging materials to food remain to be reviewed.Therefore,the author systematically reviewed the correspondence between sterilization technologies and secondary hazards generated after food packaging sterilization,the characteristics of secondary hazards,the factors affecting the formation of secondary hazards,and the detection technologies of secondary hazards.By outlining the classical migration model,the author summarized …

Lipase-Mediated Oxidation Of Furfural To Furoic Acid, Rui Zhu, Yaxin Wang, Liang Zhang

Journal of Food Science and Biotechnology

[Objective ] This study aims to develop a lipase-mediated furfural oxidation system in ionic liquid for the green synthesis of furoic acid,5-hydroxymethyl- 2-furancarboxylic acid,and 2,5-furandicarboxylic acid under mild reaction conditions.[Method ] Using furfural as the substrate,Novozym 435 lipase as the catalyst,hydrogen peroxide as the oxidant,and 1-butyl- 3-methylimidazolium acetate ionic liquid as the solvent,the conditions including reaction temperature,reaction time,initial furfural concentration,and initial hydrogen peroxide concentration were optimized.The system was further extended to the oxidation of 5-hydroxymethylfurfural,and coupled with a chemical oxidation process using an imidazolium-based ionic liquid and tert-butyl hydroperoxide to achieve one-pot synthesis of 2,5-furandicarboxylic acid.[Result ] Under the optimized …

Oral Administration Of Lacticaseibacillus Paracasei Ccfm 1433 Boosts Host Immunity To Prevent Candida Albicans Infections, Xinya Zhang, Qiuxiang Zhang, Xin Tang, Bingyong Mao, Jianxin Zhao, Shumao Cui

Journal of Food Science and Biotechnology

[Objective ] This study aims to explore the role of Lactobacillus in enhancing host immunocompetence and preventing vaginal infections with Candida albicans.[Method ] A human vaginal epithelial cell (VK2/E6E7 cell) model was employed to screen the most potent strain among ten vaginal Lactobacillus isolates in inducing the antimicrobial peptide LL- 37.A mouse model of vaginal infection with Candida albicans was established.The effects of oral administration of the selected Lactobacillus strain on vaginal mucosal immunity,systemic inflammatory balance,and vaginal microbiota homeostasis were systematically evaluated using hematoxylin-eosin (HE) staining,ELISA,qPCR,and 16S rRNA sequencing.[Result ] Both t he cell lysate and fermentation supernatant of Lacticaseibacillus …

Screening Of Excellent Lactic Acid Bacteria And Yeast Fermentation Agents And Effects Of Mixed Fermentation On The Quality Of Bread Dough, Yumeng Chen, Weijun Wang, Shuling Shen, Yanhua Li, Jingjing Ma, Menghan Huang, Yuhang Liu

Journal of Food Science and Biotechnology

[Objective ] The research on the synergistic use of lactic acid bacteria and yeast in sourdough is beneficial for meeting the industrial production demand of fermentation agents for baking food.[Method ] This study investigated the acid tolerance,acid production,enzyme production,gas production,and alcohol production abilities of various strains during the fermentation process by measuring the microbial count,pH,stretching area,elongation,hardness,viscosity,storage modulus (G′),loss modulus (G″),etc.of bread dough.The effects of different fer mentation agents on the total titratable acidity (TTA ),stretching characteristics,texture characteristics,and rheological properties of b read dough were investigated.[Result ] Lacticaseibacillus paracasei LG0260,Lactiplantibacillus plantarum LG1034,Lactococcus lactis LG0827,as well as Saccharomyces cerevisiae J2808 and S.cerevisiae …

Structural Characteristics And Antibacterial Activity Of Silver Nanoparticles Prepared From Phyllanthus Emblica Extract, Jingyuan Liu, Wenting Wang

Journal of Food Science and Biotechnology

[Objective ] The aim of this study is to investigate the structural characteristics,antibacterial activity,and antioxidant capacity of silver nanoparticles (AgNPs ) prepared from Phyllanthus emblica extract.[Method ] AgNPs were prepared with Phyllanthus emblica extract as a reducing agent.The structure of the AgNPs was characterized by X-ray diffraction (XRD ),scanning electron microscopy (SEM ),photon correlation spectroscopy (PCS ),and transmission electron microscopy (TEM ).Furthermore,the inhibitory effects of AgNPs at different mass concentrations on Escherichia coli ATCC 25922,Staphylococcus aureus ATCC 25933,and Pseudomonas aeruginosa PAO 1 were assessed,with the minimum inhibitory concentrations (MIC ) being determined.In addition,the superoxide anion and ABTS+ free radical scavenging …

Research Progress In Phytosterols (Esters ) And Their Application In Food, Shuang Mei, Huibing Luo, Tian Gan, Yonggang Qi, Chunmei Li, Chao Wang, Zao Liu

Journal of Food Science and Biotechnology

Phytosterols esters are a type of compound synthesized through the esterification reaction between phytosterols and fatty acids.To clarify the research and application of phytosterols (esters ),the author provided an overview of their structural characteristics,synthesis methods,and physiological functions.Additionally,it was elucidated that phytosterols (esters ),as functional food ingredients,play a significant role in reducing cholesterol levels and exhibiting antioxidant properties in the human body.By delving into the bioactivity of phytosterols (esters ) and enhancing peopl e’s awareness of their nutritional value,this study makes an outlook on the research and application prospects of phytosterols (esters ) in food,thereby providing a crucial theoretical basis for …

Efficient Catalytic Synthesis Of Allitol In Recombinant Escherichia Coli, Ying Cao, Peiyu Miao, Yun Liu, Zigang Zhang, Xian Zhang, Zhiming Rao

Journal of Food Science and Biotechnology

[Objective ] This study aims to enhanced the conversion efficiency of allitol through biocatalytic methods.[Methods ] The ribulose dehydrogenase (RDH ) genes rdh from Providencia alcalifaciens,Klebsiella pneumoniae and Klebsiella oxytoca were respectively expressed in Escherichia coli (E.coli ) BL21,designated as Pardh,Kprdh and Kordh respectively to identify the target genes with higher transformation rates.Further,the RDH from Klebsiella oxytoca was coupled with the formate dehydrogenase (FDH ) from Candida boidinii for co-catalysis,and the catalytic conditions and the addition amounts of co-substrates were optimized to achieve efficient enzymatic catalytic synthesis of allitol.[Results ] When using FDH and RDH from Klebsiella pneumoniae with an …

Establishment Of A Hplc-Ms/Ms Method For Determination Of Cethromycin Residue In Poultry Eggs, Chenyang Chang, Liangzi Wang, Le Wang, Kai Chang, Jiao Shan, Xiao Wang, Liqiang Guo

Journal of Food Science and Biotechnology

[Objective ] This study aims to establish a method for determining the residual amount of cethromycin in poultry eggs based on high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS ).[Method ] Four representative poultry eggs (chicken eggs,duck eggs,goose eggs,and quail eggs ) were selected as the research matrices.Cethromycin was extracted with Mcllvaine-Na 2EDTA buffer solution,purified by hydrophilic-lipophilic balanced polymer solid-phase extraction column (HLB ),separated by a C 18 column with 0.1% (volume fraction ) formic acid water and acetonitrile as the mobile phase,and determined by HPLC-MS/MS in the multiple reaction monitoring (MRM ) mode combined with an external standard method.[Result ] …

Isolation Of Three Strains Of Cordyceps Militaris And Determination Of Their Active Compounds And Antioxidant Effects, Yun Meng, Yifang Zhang, Jinduo Shi, Dun Wang

Journal of Food Science and Biotechnology

[Objective ] The strains with high-yield for active compounds such as cordycepin and cordycepic acid were screened from Cordyceps militaris (C.militaris ) collected in Shaanxi Hualongshan National Nature Reserve.[Method ] Three strains LH 3,LY1,and LY 9 of C.militaris were isolated and identified.The yields of the primary active compounds,hydroxyl radical scavenging activity,and cellular oxidative protection activity in the extracts of the mycelial and fermentation broth of each strain were determined.[Result ] The yields of cordycepic acid,crude polyphenols,and crude polysaccharides,which were the main active compounds of C.militaris,were the highest in the mycelia extract of strain LY 9,with values of 2.94,28.79,65.01 mg/g,respectively,while the …

Bifidobacterium Adolescentis Fhnfq 5m4 Modulates Gut Microbiota And Alleviates Colitis In Mice, Yi Wang, Liming Huang, Xihua Yu, Liuruolan Li, Wenwei Lu, Hongchao Wang, Zhijian Zhang

Journal of Food Science and Biotechnology

[Objective ] This study aims to verify and screen the Bifidobacterium adolescentis strains with vitamin A (VA) metabolic capacity,and investigate their effects on colitis symptoms and gut microbiota in mice.[Method ] The VA metabolic capacity of a panel of Bifidobacterium adolescentis strains was evaluated through in vitro fermentation,and the strain with the highest VA metabolic capacity was ultimately selected.This strain was administered orally to mice with dextran sulfate sodium (DSS )-induced colitis for 6 consecutive days.After the intervention,histopathological changes in the colonic tissue were assessed,and the levels of intestinal injury markers in the serum and cytokines,antioxidant enzymes,and retinoic acid (RA) …

Screening And Characterization Of Yeast Strains From Naturally Fermented Rosa Roxburghii Pomace, Yong Li, Fang Yuan, Yu Fu, Luo Peng

Journal of Food Science and Biotechnology

[Objective ] This study aimed to develop high-quality fermented Rosa roxburghii (R.roxburghii ) products by screening yeast strains suitable for R.roxburghii fermentation.[Method ] The naturally fermented R.roxburghi pomace was used as the material for preliminary screening through the TTC colorimetric method and secondary screening based on fermentation capacity.The tolerance of strains to SO 2,ethanol,low pH,and glucose was examined.The strains were identified via morphological characterization and molecular biological techniques.[Result ] Three high-performing strains (B17,B19,and B29) were obtained.These strains exhibited tolerance to 250 mg/L SO 2,mass fraction 60% glucose,volume fraction 8% ethanol,and pH 3.5 environment.B17 and B 29 were identified as Pichia …