Digital Commons Network^™

Bonding With Earth: Hyperbole, Metaphor, Or Fanciful Teleology?, George Conesa

The International Journal of Ecopsychology (IJE)

At a mere glance, the notion that humans could (should strive for?) bond emotionally with an entire planet, Earth, sounds hyperbolic at best and psychologically unsound at worst. For although humans might be motivated to act in ways that pass for “bonding,” perhaps assisted by intentions and sentiments to care for a whole planet, the question remains: Which notion of Earth are they really investing all their emotions in? Important to psychologists would be to inquire whether incomplete, idealized, oversimplified, or fantastic notions of “Earth,” or bonding, turn out to be transference-love-like, platonic, overidealized forms of affect, which seldom develop …

Life Goes On, But Better, Editorial Board

The International Journal of Ecopsychology (IJE)

" … During a solar flare* An exchange between two telegraph operators during the Carrington Event, the most intense solar flare recorded to date (September 2, 1859. Boston Evening Traveler)."

Table Of Contents September 2025 Vol11/1, Editorial Board

The International Journal of Ecopsychology (IJE)

No abstract provided.

Self-Transcendent Experiences As Promoters Of Ecological Wellbeing? Exploration Of The Evidence And Hypotheses To Be Tested, Amy Isham

The International Journal of Ecopsychology (IJE)

In recent years, much has been written on the role of different mental states and their potential to influence our way of thinking and, perhaps more importantly, the way we act. With the recent acceleration of environmental and mental health issues, alongside the limited effectiveness of existing interventions, an exploration of new approaches to deliver transformative change is required. We therefore explore the emerging potential of a type of mental state known as self-transcendent experiences (STEs) as a driver of ecological wellbeing. We focus on four types of STEs: those facilitated by experiences of flow, awe, and mindfulness, as well …

Setd2 Suppresses Tumorigenesis In A Krasg12c-Driven Lung Cancer Model, And Its Catalytic Activity Is Regulated By Histone Acetylation, Ricardo J Mack, Natasha M Flores, Geoffrey C Fox, Hanyang Dong, Metehan Cebeci, Simone Hausmann, Tourkian Chasan, Jill M Dowen, Brian D Strahl, Pawel K Mazur, Or Gozani

Faculty, Staff and Student Publications

Histone H3 trimethylation at lysine 36 (H3K36me3) is a key chromatin modification that regulates fundamental physiological and pathological processes. In humans, SETD2 is the only known enzyme that catalyzes H3K36me3 in somatic cells and is implicated in tumor suppression across multiple cancer types. While there is considerable crosstalk between the SETD2-H3K36me3 axis and other epigenetic modifications, much remains to be understood. Here, we show that Setd2 functions as a potent tumor suppressor in a KRASG12C-driven lung adenocarcinoma (LUAD) mouse model, and that acetylation enhances SETD2 in vitro methylation of H3K36 on nucleosome substrates. In vivo, Setd2 ablation accelerates lethality in …

Bayesian Clustering Prior With Overlapping Indices For Effective Use Of Multisource External Data, Xuetao Lu, J Jack Lee

Faculty, Staff and Student Publications

The use of external data in clinical trials offers numerous advantages, such as reducing enrollment, increasing study power, and shortening trial duration. In Bayesian inference, information in external data can be transferred into an informative prior for future borrowing (i.e. prior synthesis). However, multisource external data often exhibits heterogeneity, which can cause information distortion during the prior synthesizing. Clustering helps identifying the heterogeneity, enhancing the congruence between synthesized prior and external data. Obtaining optimal clustering is challenging due to the trade-off between congruence with external data and robustness to future data. We introduce two overlapping indices: the overlapping clustering index …

Poem: At Castle Island, Lake Superior By Jane Johnston Schoolcraft, Editorial Board

The International Journal of Ecopsychology (IJE)

"Here in my native inland sea/ From pain and sickness would I flee/ And from its shores and island bright/ Gather a store of sweet delight. [...] Far from the haunts of men away/ For here, there are no sordid fears,/ No crimes, no misery, no tears/ No pride of wealth; the heart to fill,/ No laws to try my people ill.

Cinnamon Bark Oil Application And Modified Atmosphere Packaging Alleviates Chilling Injury, Ethylene Production And Maintains Antioxidant System In Persimmons, Mahmood Ul Hasan, Zora Singh, Hafiz Muhammad Shoaib Shah, Muhammad Rizwan Azhar, Eben Afrifa-Yamoah, Andrew Woodward

Research outputs 2022 to 2026

Persimmon fruit is highly susceptible to chilling injury (CI) during cold storage. This study was aimed at evaluating the effects of cinnamon bark oil (CBO, 4 μM) fumigation, modified atmosphere packaging (MAP), and a combination of CBO and MAP on CI of ‘Fuyu’ persimmons. Fourier-transform infrared (FT-IR) analysis revealed changes in the peel surface of CBO fumigated persimmons. Peel and flesh CI incidence and CI index were significantly reduced with a combined application of CBO and MAP. CBO + MAP exhibited lower ethylene production, malondialdehyde (MDA), hydrogen peroxide (H2O2), and lipoxygenase (LOX) activity, maintained higher flavonoids, and upregulated the ascorbate …

Alpiscorpius Huyukensis Sp. N., An Unexpected New Species From Sultan Mountains, Konya Province, Turkey (Scorpiones: Euscorpiidae), Ersen A. Yağmur, Halil İ. Yaylı

Euscorpius

A new scorpion species, Alpiscorpius huyukensis sp. n., is described from the western foothills of the Sultan Mountains, Konya Province, in the Aegean Region of western Turkey, based on morphological characters. The species is assigned to the genus Alpiscorpius Gantenbein et al., 1999, due to the presence of three trichobothria in the em series on the external surface of the pedipalp patella. A. huyukensis sp. n. can be readily distinguished from its all congeners by its yellowish-orange or greyish-orange body and yellow metasomal coloration, the fifth metasomal segment bearing distinct ventrolateral carinae, the presence of six trichobothria in the …

Low Energy Availability Prevalence, Dietary Habits, And Sleep In Female Army Rotc Cadets, Hannah K. Eberhardt, Brandon D. Willingham, Matthew F. Brisebois, Patrick G. Saracino

International Journal of Exercise Science

International Journal of Exercise Science 18(6): 1030-1046, 2025. Low energy availability (LEA) results in numerous health and performance decrements. While a high prevalence of LEA and sleep disturbance has been observed in male Army Reserve Officers’ Training Corps (ROTC) cadets, no data exists in females. This study aimed to determine LEA prevalence, dietary habits, and sleep quantity and quality in female U.S. ROTC cadets. Following an overnight fast, ten cadets (22±4 yrs, 166.0±6.1 cm, 67.1±9.1 kg, 26.1±6.2% body fat, 49.2±4.8 kg fat-free mass (FFM)) had their body composition and resting metabolic rate measured. Validated questionnaires assessed LEA symptoms and sleep. …

Preclinical Perspectives On Disorders Of The Temporomandibular Joint: Tracing The Past, Navigating The Present, And Shaping The Future, John K Neubert, Kyle Allen, Tamara Alliston, Alejandro J Almarza, Kyriacos A Athanasiou, Basak Donertas-Ayaz, Bruna Balbino De Paula, Roxanne Bavarian, Nidhi Bhutani, Brian E Cairns, Robert M Caudle, Yang Chai, Jian-Fu Chen, Yong Chen, Glenn T Clark, Yenisel Cruz-Almeida, Alexandre F Dasilva, Paul L Durham, Airam Vivanco Estela, Millie Embree, Roger Fillingim, Fernando Guastaldi, Shruti Handa, Sunil D Kapila, David Keith, Keith L Kirkwood, Phillip Kramer, Katherine T Martucci, Niall P Murphy, Andrea G Nackley, Richard Ohrbach, Benedikt Sagl, Shad B Smith, Feng Tao, Beth Winkelstein, Hai Yao, Simon Young, Michael S Gold

Faculty, Staff and Student Publications

Temporomandibular disorders (TMDs) are complex conditions characterized by orofacial pain and dysfunction, affecting a significant portion of the population. TMDs may involve joint and/or muscle pain, dysfunction (e.g., noise, limited or altered jaw movements), or both, leading to a marked decrease in quality of life. Patients often experience functional limitations that hinder eating, speaking, and daily activities. Additionally, TMDs are frequently associated with psychological distress, including anxiety and depression, which further impacts overall well-being. Despite the profound individual and societal impact of TMDs, effective therapies remain elusive, partly due to deficiencies in translational research. A primary limitation in the TMD …

Bees (Hymenoptera: Anthophila) Of Seasonal Herbaceous Wetlands In Mississippi, Haley Hughes, Katherine A. Parys, Kim T. Huntzinger, Caleb Lankford, Christine Fortuin, J. Brian Davis

Publications

Seasonal wetlands help meet the biological needs of various autumn migrating and wintering waterfowl species in North America (Reinecke et al. 1989). Management of seasonally flooded impoundments often uses soil and vegetation disturbances and water management to promote early succession plants that produce abundant seeds for foraging birds (Low and Bellrose 1944, Kross et al. 2008). Native bees (Hymenoptera: Anthophila) also occupy these wetland habitats, as they are attracted to a diversity of flowering plants (Stephenson et al. 2018).

The Mississippi Alluvial Valley (MAV) is an alluvial plain and once represented by nearly 10 million ha of bottomland hardwood forests, …

Effects Of Elevated Nutrient Supply On Litter Decomposition Are Robust To Impacts Of Mammalian Herbivores Across Diverse Grasslands, Adrienne B. Keller, Elizabeth T. Borer, Christopher R. Buyarski, Elsa E. Cleland, Allison Gill, Andrew S. Macdougall, Joslin L. Moore, John W. Morgan, Rebecca L. Mcculley, Anita C. Risch, Eric W. Seabloom, Justin Wright, Sarah E. Hobbie

Michigan Tech Publications

Litter decomposition is one of the largest carbon (C) fluxes in terrestrial ecosystems and links aboveground biomass to soil C pools. In grasslands, decomposition drivers have received substantial attention but the role of grassland herbivores in influencing decay rates is often ignored despite their potentially large effects on standing biomass and nutrient cycling. Recent work has demonstrated that nutrient addition increases early-stage decay and suppresses late-stage decay. Mammalian herbivores can mediate the effects of nutrient supply on biomass, suggesting herbivores may alter the effects of nutrients on decomposition, though this is largely unknown. We examined how herbivory mediates the effects …

Age-Dependent Changes In Reproductive Behaviour And Success In A Long-Lived Beetle (Bolitotherus Cornutus), C. A. Greene, L. D. Mitchem, Vitor Dos Anjos , '21, E. D. Brodie Iii, Vincent A. Formica

Biology Faculty Works

Age-related changes in behaviors often result in shifts in an individual’s competitive ability, reproductive success, and fitness. However, how mating behaviors, aggression, and mating success simultaneously change as individuals age in natural populations remains understudied. Investigating these age-dependent effects in wild populations could reveal how age-specific patterns shape social dynamics and influence natural selection. In this study, we ask how behaviors associated with mating and reproductive success vary across age in a wild metapopulation of a long-lived beetle, Bolitotherus cornutus. We used both cross-sectional and longitudinal data from a multi-year field study of individually marked beetles to investigate how …

In Vivo Efficacy Of A Broad-Spectrum Antiviral Combination Against Yellow Fever In A Hamster Model, Abbie E. Weight, Hunter Stanger, Robert J. Geraghty, Laurent F. Bonnac, Justin G. Julander

Animal, Dairy, and Veterinary Science Student Research

Yellow fever virus (YFV) recurrently causes severe outbreaks in tropical regions of South America and Africa and an average of 30 to 40 thousand deaths worldwide each year. An effective vaccine is available but the coverage of the population in countries at risk is not optimal. No antivirals are currently approved for YFV treatment. Herein, we describe the evaluation of 6-MMPr, a de-novo-purine-nucleotide biosynthesis inhibitor, as a potentiator for enhanced activity of the broad-spectrum antiviral drug favipiravir in a hamster model of yellow fever. Administration of 6-MMPr was well-tolerated and a combination of favipiravir and 6-MMPr did not cause …

Amaranthus Spp. Control And Sweetpotato Tolerance To Fluridone-Containing Herbicide Programs, Stephen L. Meyers, Katherine M. Jennings, Mark W. Shankle, Jeffrey L. Main

Publications

Click on author name to view affiliation information Article Category: Research Article Online Publication Date: 12 Sept 2025 Page(s): 843 – 847 Volume/Issue: Volume 35: Issue 5 DOI: 10.21273/HORTTECH05727-25

Open Access

Abstract

Field studies were conducted at the Pontotoc Ridge–Flatwoods Branch Experiment Station in Pontotoc, MS, USA and the Horticultural Crops Research Station in Clinton, NC, USA in 2015 to determine pigweed (Amaranthus spp.) control and sweetpotato (Ipomoea batatas) crop response to fluridone herbicide. Treatments consisted of 168 g·ha⁻¹ a.i. fluridone alone or tank-mixed with 54 g or 107 g·ha⁻¹ a.i. flumioxazin applied pretransplanting, fluridone/flumioxazin …

Resolution Of Physics And Deep Learning-Based Protein Engineering Filters: A Case Study With A Lipase For Industrial Substrate Hydrolysis, Spencer Gardiner, Peter Dollinger, Filip Kovacic, Jörge Pietruszka, Daniel Ess, Karl-Erich Jaeger, Gunnar F. Schröder, Dennis Della Corte

Faculty Publications

Computational enzyme design remains a powerful yet imperfect tool for optimizing biocatalysts, especially when targeting non-natural substrates. Using design tools we investigated Pseudomonas aeruginosa LipA, a lipase with a flexible lid domain crucial for substrate binding and turnover, aiming to enhance its hydrolysis of the industrially relevant substrate Roche ester. We generated an initial set of single-point mutations based on structural proximity to the active site and evaluated their effects using a computational pipeline integrating molecular dynamics (MD) simulations, density functional theory (DFT) calculations, and ensemble-based energy scoring. While we identified several active variants, attempts to rank them by activity …

Systematics And Phylogeography Of Mundochthonius Chamberlin, 1929, In The Pacific Northwest (Chelicerata, Pseudoscorpiones), Amanda Rai Montoya-Cowan

Dissertations and Theses

Understanding the processes that drive genetic divergence and species formation is central to evolutionary biology. Invertebrates with low dispersal ability, such as pseudoscorpions, are especially prone to cryptic diversification due to their occupancy of niche microhabitats and sensitivity to landscape barriers. Despite their ecological roles as predators and bioindicators, pseudoscorpions remain one of the least studied arachnid groups, with limited taxonomic resolution and few integrative studies. This research focuses on the genus Mundochthonius in the Pacific Northwest, particularly M. pacificus, a morphologically conserved species whose true diversity and distribution remain poorly understood.

Field surveys guided by a GIS-based habitat …

Structural Analysis Of Pseudomonas Phage Dev Virion-Associated Rna Polymerase (Gp71), James Scherer

All ETDs from UAB

DEV is a Pseudomonas aeruginosa bacteriophage part of a newly reclassified genus called Schitoviridae. This group of bacteriophages is also referred to as “N4-like” phages, after the prototypical Escherichia coli phage N4, originally isolated from sewage water in 19661. N4, and other phages in the group, contain a large, virion-associated RNA polymerase (vRNAP). This vRNAP is vital to the proliferation of the phage, as it performs the transcription of the early gene products and potentially acts as a motor that helps eject the viral genome into the host bacteria. In DEV, the vRNAP is also known as gene product 71 …

Draft Genome Sequence Of Staphylococcus Aureus N208 Isolated From A Nasal Swab Of A Healthy Female, Sandra Jablonska, Lila Nelson, Grace Finger, Alex Kula, Catherine Putonti

Biology: Faculty Publications and Other Works

Staphylococcus aureus, a common member of the healthy human microbiota, is an opportunistic pathogen. To investigate the genomic features of this species in healthy individuals, we present the draft genome sequence of S. aureus N208, isolated from a nasal swab collected from a healthy female participant.

Infusion Of Blood From Young And Old Mice Modulates Amyloid Pathology, Matias Pizarro, Ruben Gomez-Gutierrez, Ariel Caviedes, Catalina Valdes, Ute Woehlbier, Cristian Vargas, Mauricio Hernandez, Claudia Duran-Aniotz, Rodrigo Morales

Faculty, Staff and Student Publications

Alzheimer's disease (AD) is a neurodegenerative disease characterized by the accumulation of misfolded proteins in the brain. Recently, the impact of blood components in the progression of this disease has come to attention. This study investigates the effects of infusing blood from young and old wild-type mice into transgenic mice that model AD brain amyloidosis. Impaired memory and Aβ accumulation were observed in mice infused with blood from old donors. A proteomic analysis in the brain of these mice identified alterations in components related to synaptogenesis and the endocannabinoid system. The α2δ2 protein, associated with neuronal calcium regulation, was validated …

Loss Of Ptdss1 In Tumor Cells Improves Immunogenicity And Response To Anti-Pd-1 Therapy, Jielin Liu, Shelley Herbrich, Sreyashi Basu, Yulong Chen, Ashwat Nagarajan, Swetha Anandhan, Sangeeta Goswami, Liangwen Xiong, Baoxiang Guan, Padmanee Sharma

Faculty, Staff and Student Publications

PTDSS1 (phosphatidylserine synthase 1) encodes an enzyme that facilitates production of phosphatidylserine (PS), which mediates a global immunosuppressive signal. Here, based on in vivo CRISPR screen, we identified PTDSS1 as a target to improve anti-PD-1 therapy. Depletion of Ptdss1 in tumor cells increased expression of interferon-γ (IFN-γ)-regulated genes, including B2m, Cxcl9, Cxcl10, and Stat1, even in the absence of IFN-γ stimulation in vitro. Loss of Ptdss1 in tumor cells also led to increased expression of MHC-I, enhanced cytotoxicity of CD8+ T cells, and increased frequency of an iNOS+ myeloid subset. A gene signature derived from the …

A Novel Sialylation Pathway Mediated By Extracellular Vesicles In Aggressive Prostate Cancer, Camila A. Bach, Md Niamat Hossain, Ishan J. Chaudhari, Cecilia E. Verrillo, Nicole M. Naranjo, Isabella Amoroso, Anna Testa, Samuel Sey, W. Kevin Kelly, Susan L. Bellis, Aurelio Lorico, Ada G. Blidner, Gabriel A. Rabinovich, Lucia R. Languino

Department of Pharmacology, Physiology, and Cancer Biology Faculty Papers

Altered cell surface glycosylation is a hallmark of cancer; among aberrant glycan structures, hypersialylated proteins contribute to disease progression. The enzyme ST6 β-galactoside α2,6-sialyltransferase 1 (ST6GAL1) mediates α2,6-linked sialylation of N-glycosylated proteins and is upregulated in many cancers, including prostate cancer (PrCa). We propose that ST6GAL1 may be released by cancer cells in small extracellular vesicles (sEVs) in the PrCa tumor microenvironment to potentially modulate cell surface sialylation in recipient cells. We isolated sEVs from PrCa cells by density gradient separation and characterized them by nanoparticle tracking analysis using ZetaView and immunoblotting analysis. We identified ST6GAL1 in both its membrane-bound …

Observations On Predation Of The Flatback Turtle Natator Depressus By The Saltwater Crocodile Crocodylus Porosus At A Major Rookery In Northern Australia, Casper Avenant, James Gee

Research outputs 2022 to 2026

Context: We examined predation by the saltwater crocodile (Crocodylus porosus) on the flatback turtle (Natator depressus), an Australian endemic, at Cape Domett, a significant nesting site in Cambridge Gulf, northern Australia, where crocodile populations have recovered since legislative protection was implemented in the 1970s. Aims: The investigation aimed to document crocodile predation on flatback turtles across hatchling and adult life stages, assess predation strategies, and evaluate ecological impacts on this genetically distinct turtle stock. Methods: Conducted over three Austral winters (2021–2023), the study utilised infrared videography, unmanned aerial vehicles, and beach patrols to observe predation events in a population of …

Guiding With Love: Building Self-Regulation Through Structure And Warmth, Kylie Collette

Family Perspectives

No abstract provided.

The Value Of Play In Improving Children’S Experiences With Healthcare, Kylie Howes

Family Perspectives

Hospitalization can be a distressing experience for children, often resulting in heightened anxiety and pain due to unfamiliar environments, procedures, and personnel. This literature review examines the effectiveness of Child Life Play Interventions—specifically Developmentally Supportive Play, Psychological Preparation Play, and Distraction Play—in reducing pediatric patients’ healthcare- related anxiety and pain. Developmentally supportive play provides children with familiar, age-appropriate activities that help maintain normalcy and routine, thereby reducing stress during extended hospital stays. Psychological preparation play uses role-playing and hands-on demonstrations to enhance children’s understanding of medical procedures, alleviating anxiety and decreasing perceived pain. Distraction play shifts children’s attention away from …

When Evidence Is Shocking: The Value Of Struggling With Uncomfortable Ideas, Cortney Evans-Stout, Christin L. Porter

Family Perspectives

No abstract provided.

Marital Conflict And Male Depression: The Role Of Emotional Withdrawal And Hostility, Nicolas Enzo Mouhsen

Family Perspectives

This literature review investigates the relationship between marital conflict and male depression, focusing on emotional withdrawal and spousal hostility as key contributing factors. Male depression, often underreported due to differences in symptom expression such as anger and irritability, is explored in the context of marital dynamics. Emotional withdrawal, characterized by avoidance behaviors during conflict, is particularly prevalent among men and linked to rigid gender role perceptions. This behavior correlates with increased depressive symptoms and reduced well-being. Additionally, spousal hostility, including verbal aggression and criticism, exacerbates male depression through both the perception of aggression from a partner and self-awareness of hostile …

Divorced After Age 50: What Gray Divorced Women Can Do To Move Forward, Sheri Duvall

Family Perspectives

No abstract provided.

The Benefits Of Combining Center-Based And Home-Based Care For Preschool Children, Savannah Christensen

Family Perspectives

Abstract: Research shows that the quality of care children receive in early childhood—whether from a parent, relative, or formal child care provider—significantly influences their cognitive, behavioral, and emotional development. This article analyzes several peer-reviewed sources to examine how different caregiving environments impact development and how these effects are moderated by the quality of care and the home environment. It also addresses how socioeconomic status can shape the quality of care children receive and the long-term outcomes associated with each caregiving type. While parents are typically seen as the ideal caregivers, children in nonparental care, such as with relatives or in …