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Why The Long Face? The Distribution And Niche Of The Imperiled Narrow-Faced Kangaroo Rat (Dipodomys Venustus), Garrett L. Gimbel

Master's Theses

Distribution models provide a practical use case of connecting ecological niche theory with species’ occurrence and assemblages. By explicitly linking Hutchinson’s “niche space” with geographic space researchers can gain valuable information on a species’ niche characteristics and interactions, thereby informing conservation and management practices. The narrow-faced kangaroo rat (Dipodomys venustus) is a highly understudied kangaroo rat species endemic to the central coast of California and is an ideal species to explore niche theory in distribution modeling. Three subspecies are currently recognized: The Santa Cruz kangaroo rat (D. v. venustus), the elephant-eared kangaroo rat (D. v. …

Bedstraw Eradication Program 2024-25: Annual Report To Grain Growers, Department Of Primary Industries And Regional Development, Western Australia

Biosecurity published reports

The Bedstraw Eradication Program operates under the Biosecurity and Agricultural Management Industry Funding Scheme (Grains) Regulations 2010.

Approved Plans developed annually for each infested property in consultation with the Grains, Seeds and Hay Industry Management Committee (GSHIMC), the Department of Primary Industries and Regional Development (DPIRD) and the landholders detail management actions, estimated costs and timeframes of agreed actions.

Skeleton Weed Program 2024-25: Annual Report To Grain Growers, Department Of Primary Industries And Regional Development, Western Australia

Biosecurity published reports

Skeleton weed is a major pest of grain crops and can significantly reduce grain crop yields by competing for moisture and nutrients (mainly nitrogen), due to its deep perennial root system.

Skeleton weed is a declared plant in WA under section 22 of the Biosecurity and Agriculture Management Act (2007) and is assigned to control category 2 (Eradication) for the whole of the State, except in the Narembeen and Yilgarn Shires, where it is category 3 (Management).

Modelling indicates that under a nil management scenario, the cost to WA broadacre agriculture will be approximately $19.2 million per year after twenty …

Asymptomatic Cryptococcal Antigenemia: A Multi-Clinic Cross-Sectional Study On The Prevalence, Associated Factors And Predictors Of Three-Month Outcomes Among Antiretroviralnaïve And Antiretroviral-Experienced Hiv Patients In Dar Es Salaam, Tanzania, Mandela Makakala, Mukasa Mohammed, Mabula Mabelele, Kamran Hameed, Philip Adebayo

Internal Medicine, East Africa

Background: Cryptococcal meningitis remains a leading cause of HIV/AIDS-related mortality, predominantly in Sub-Saharan Africa. Current screening and prevention efforts primarily target antiretroviral therapy (ART)-naïve patients, whereas strategies for ART-experienced individuals are less well defined.

Objectives: This study primarily aimed at determining the prevalence of asymptomatic cryptococcal antigenemia (ACA) among ART-naïve and ART-experienced patients, along with associated factors and predictors of three-month outcomes among HIV patients in three HIV clinics in Dar es Salaam, Tanzania. Secondarily, factors associated with serum cryptococcal antigen positivity in the overall study population were also assessed.

Methods: This cross-sectional clinic-based study recruited 273 HIV-positive participants (ART-naïve …

An Update On Novel Taxa And Revised Taxonomic Status Of Bacteria Isolated From Human Clinical Specimens Described In 2024, Arianna Carella, Karen C. Carroll, Erik Munson

Clinical Lab Sciences Faculty Research and Publications

Knowledge of novel and revised bacterial taxonomy facilitates routine operations in the medical microbiology laboratory and communication with important stakeholders. Notable new gram-positive taxa accepted in 2024 include the clinically significant Staphylococcus brunensis sp. nov., as well as Streptococcus suis subsp. hashimotonensis subsp. nov., which can be delineated from other Streptococcus suis subsp. by possession of the Lancefield group A antigen. Four novel Enterobacterales species are discussed, plus a novel eighth family Gallaecimonadaceae. One of these, Providencia huashanensis sp. nov. is clinically significant and harbors multiple genetic determinants that encode antimicrobial resistance mechanisms. Stenotrophomonas forensis sp. nov., derived from …

Blood-Based Clinical Markers For Early Dementia Detection: Insights From Ad-Detect-Cohort, Benard Aliwa, Jasmit Shah, Olivera Nesic Taylor,, Samuel Nguku, Juzar Hooker, Dilraj Sokhi, Sylvia Mbugua, Litha Musili, Rachel Maina, Harrison Kaleli, Levi Muyela, Anne Njoki Gitere, Anne Nyambura, Zul Merali, Karen Blackmon, Chinedu Momoh

Brain and Mind Institute

Background: Over 55 million people worldwide live with dementia, with more than60% residing in low- and middle-income countries. Alzheimer’s disease, the mostcommon form of dementia, accounts for 60–70% of cases. Early and accurate diagnosisremains a global challenge, necessitating novel approaches to mitigate the diseaseburden. Biomarkers hold significant promise in improving diagnostic accuracy andpredicting disease progression. Validated biomarkers for the preclinical stages ofdementia are crucial for advancing diagnosis and therapeutic strategies. We aimedto identify potential clinical markers for early dementia detection and assess theirpredictive accuracy in identifying high-risk individuals.

Method: We analyzed blood samples from dementia cases (n = 30) and …

National-Scale Open Cattle Feedlot Detection Using Deep Learning And High-Resolution Aerial Images: Spatial Distribution And Animal Welfare Analysis, Uilson Ricardo Venancio Aires, Vitor Souza Martins, Dakota Hester, Thainara Lima, Lucas Borges Ferreira

Research Data

Open cattle feedlots are a major form of beef production infrastructure in the United States, characterized by outdoor confinement, high animal densities, and regulated feeding practices. Despite their economic importance, a comprehensive and spatially consistent national database of these facilities remains limited. This dataset provides labeled training data, trained deep learning models, and geospatial detection outputs developed to support automated identification of open cattle feedlots from aerial imagery. The dataset includes a manually curated shapefile of 11,746 open cattle feedlot facilities identified through visual interpretation of high-resolution aerial imagery in highly productive counties of Nebraska, Kansas, and Texas. These labels …

Dual-Stage Ultrasound Application For Rice Bran Protein Extraction: A Novel Method To Improve Yield, Functional Properties, And Nutritional Profile, Saydul Md Safwa, Nikitha Modupalli, Md Mahfuzur Rahman

Food Science Faculty Publications and Presentations

While ultrasound-assisted protein extraction is well-studied, the application of ultrasound in both the extraction and precipitation stages has not been explored. This study explored the ultrasound (U)-assisted alkaline extraction (AE) at pH 9.5 and ultrasound-assisted isoelectric precipitation (UIP) at pH 3.5 on the rice bran protein yield, functionality, and nutritional quality. The UAE and conventional precipitation (UAE-IP) yielded the highest protein yield of 65.7 %, while conventional extraction yielded 38.9 %. FTIR showed that UAE-IP increased beta-sheets by 96.8 % while AE-UIP decreased the alpha-helices by 42.4 %. Although UAE-IP showed no significant change in surface hydrophobicity, UAE-UIP decreased it …

Effects Of Injectable Trace Mineral Timing On Calf Performance And Health Indicators, Marie E. Goulais

Graduate Theses and Dissertations

One hundred and fourteen calves (average BW= 224kg ± 89kg) were utilized to evaluate the effects of injectable trace mineral (ITM) administration on calf performance and health when administered pre-weaning and at weaning. Calves were blocked by sex, stratified by age, and randomly assigned to one of the following treatment groups: 1) no ITM injection (CON), 2) ITM administered 28 d before weaning (PW), or 3) ITM administration at weaning (WEAN). Calves were vaccinated against respiratory pathogens on D-28 and D0. At weaning, cattle were transported to a local auction market, held overnight and returned the following morning. Body weight …

Effect Of Peracetic Acid Dip Frequency On The Quality And Functional Properties Of Non-Marinated And Marinated Broiler Tenderloins, Joaquin Jose Esquivel Vergara

Graduate Theses and Dissertations

The poultry industry continues to balance the need for effective antimicrobial interventions with the preservation of meat quality. Among the most widely used antimicrobial agents, peracetic acid (PAA) has proven effective for reducing foodborne pathogens in poultry products. However, excessive or repeated exposure to PAA can influence meat functionality by altering protein structure, color, and water-holding capacity. Therefore, the broad objective of this study was to evaluate the effect of PAA dip frequency and post-treatment marination timing on the physicochemical and functional quality of broiler tenderloins (Pectoralis minor), in order to provide processing insights that optimize both microbial safety and …

Hormonal Control Of Seawater Acclimation In The Intestine Of The Atlantic Killifish (Fundulus Heteroclitus), Karma Je Hine

Graduate Theses and Dissertations

The Atlantic killifish (Fundulus Heteroclitus) is a teleost found in brackish water estuaries, which are subject to large fluctuations in salinity, that handles osmotic stress by triggering compensatory actions across their osmoregulatory organs. As the external salinity increases, the killifish intestine exhibits a high degree of phenotypic plasticity, as the protein composition of the gut epithelium can be modified to absorb desalinated water (H2O) from ingested seawater (SW). Three osmoregulatory hormones, prolactin (P), growth hormone (GH), and cortisol (F), have been observed to be crucial for these transitions to occur in many species of teleosts, including killifish. This research sought …

(R2135) System Dynamical Analysis For Ann-Based Numerical Solutions Of A Compartmental Model: A Bio-Mathematical Model Of Drug Diffusion Through The Compartments Of Blood And Tissue, Rakesh Kumar, Sudarshan Dhua

Applications and Applied Mathematics: An International Journal (AAM)

This paper provides a considerably efficient numerical approach to acquire the solutions of a biomathematical model administrating oral and intravenous distribution of pharmaceuticals in the human body. The proposed numerical approach based on an artificial neural network is employed to extract numerical solutions for a detailed set of ordinary differential equations and analyze the change in concentration of drug diffusion via the compartments of blood and tissue medium. We primarily focus on analyzing three different models established on the diffusion process, exercising laws of mass action and Fick’s principle. In this work, the existing model is reformulated as an optimization …

(R2107) Analysis Of A Bivalent Vaccine Model With Peer Influence Effect On Testing, Manoj Kumar Singh, Anjali .

Applications and Applied Mathematics: An International Journal (AAM)

The coronavirus caused havoc around the world. There was a terrible situation in villages and cities, and no one knew how to deal with it. Although the governments of each country tried their best to save the common people, vaccination programs and testing centers were built everywhere. However, people were not utilizing it due to fear. Because of this, the infection spread rapidly. The qualitative study of the mathematical model here is in context with the situation when bivalent vaccination and testing are available for an epidemic. The mathematical model combines the exposed period and influenza model with vaccination included …

Differences In Loading Rate In Shod And Unshod Treadmill Walking, David Austin Kropushek

Master's Theses

The purpose of this study was to compare the loading rates of shod and unshod conditions in treadmill walking. It was hypothesized that walking barefoot would demonstrate higher loading rates than walking with shoes. It was also hypothesized that walking barefoot on a treadmill would result in greater stride-to-stride variability than walking with shoes. Sixteen healthy adult females volunteered and provided their consent to participate in this study. Participants were given time to accommodate to the instrumented treadmill both while wearing shoes and without. Two 10-minute trials were collected with a rest period between. Data were analyzed using Vicon Nexus …

Validation Of Diagnostic Markers And Linkage Mapping In Vitis × Muscadinia Hybrids, Isabella Vaughn

Graduate Theses and Dissertations

The Vitis genus comprises two subgenera, Vitis (2n = 38) and Muscadinia (2n = 40), both cultivated for wine, juice, and fresh-market fruit. Vitis vinifera cultivars produce high-quality fruit but are highly susceptible to diseases endemic to the southeastern United States, while muscadines (Muscadinia rotundifolia) provide exceptional disease resistance, heat tolerance, and environmental adaptability. Hybridizing these subgenera offers a path to combine fruit quality with disease resistance; however, wide Vitis × Muscadinia (V × M) crosses remain difficult due to differences in chromosome number, genetic divergence, and reproductive barriers that reduce fertility and recombination. Recent breeding efforts have introgressed stenospermocarpic …

Transcription Factors And Regulatory Proteins In The Control Of Eukaryotic Gene Expression, Maya M. Minkara

Honors Theses

Transcription factors (TFs) function as precision switches that integrate signaling inputs, chromatin state, and protein homeostasis to control gene expression. This thesis unites three interconnected research themes: (1) mechanistic studies of the ubiquitin-proteasome system (UPS) in regulating eukaryotic TFs, focusing on polymerase-associated Factor 1 (Paf1) and TATA-box binding protein-associated factor 2 (Taf2); (2) identification of biomarker genes within odor-related TF networks; and (3) integration of published undergraduate research linking molecular regulation, bioinformatics, and synthetic biology. These themes are purposefully structured so that mechanistic insight into TF control sets up network-level discovery and, in turn, motivates applied and translational directions. In …

Predicting Accelerated And Delayed Aging In Global Settings: Biobehavioral Age Gaps And The Role Of Global Exposomes, Hernan Hernandez, Hernando Santamaria-Garcia, Sebastian Moguilne, Agustina Legaz, Pavel Prado, Jhosmary Cuadros, Liset Gonzalez, Cyprian Mostert, Chinedu Momoh, Zul Merali

Brain and Mind Institute

Background: Global health challenges like aging and dementia are shaped bysocioeconomic disparities, environmental factors, and social determinants of health.We developed a behavioral age gap (BAG), measuring the difference between expectedbehavioral age and chronological age

Method: We utilized a cross-sectional sample (n = 161,981) comprising countriesfrom Latin America, Europe, Asia, and Africa. Behavioral age was estimated usinga Gradient Boosting Regressor with 10-fold cross-validation, incorporating multiplerisk factors (hypertension, diabetes, heart disease, female sex, visual impairment andhearing impairment) and protective factors (cognition, functional ability, education)associated with healthy aging. BAG was calculated as the difference between predictedand chronological age, and adjusted gaps were derived …

Avaren-Fc's Effects On Lymphoma Cells., Jacob Hahn

Electronic Theses and Dissertations

This thesis investigates the therapeutic potential of Avaren-Fc (AvFc), a novel lectin fusion protein that integrates the Fc region of human IgG1 with the engineered lectin Avaren, specifically targeting lymphoma. The study delineates the in vitro binding capabilities of Avaren-Fc with a human B-cell lymphoma cell line, a canine B-cell lymphoma cell line, healthy canine peripheral blood mononuclear cells (PBMCs), and healthy human PBMCs. AvFc was shown to exhibit significant binding to human lymphoma cells. Furthermore, the direct cytotoxicity of Avaren-Fc against canine lymphoma cells, canine lymphoma cells and healthy canine PBMCs was assessed. It was found that there is …

Enzymatic Depletion Of Adenosine To Potentiate Cancer Immunotherapy., Omar Sadi Sarkar

Electronic Theses and Dissertations

Immune checkpoint blockade (ICB) therapies have revolutionized cancer treatment, but many patients still do not respond well. To improve therapeutic outcomes, chemotherapy is often combined with immunotherapy, as chemotherapy is known to promote immunogenicity. However, many patients develop resistance to this combination therapy, and the reasons behind it are not fully understood. In this study, we explored how platinum-based chemotherapy, specifically cisplatin, affects tumor signaling to create an immunosuppressive tumor microenvironment (TME). We found cisplatin triggers ataxia telangiectasia mutated (ATM)-mediated DNA damage signaling and induces higher expression of prostaglandin E₂ (PGE₂) via a cyclooxygenase-2 (COX-2) mediated pathway. We speculate DNA …

Examing Fear Conditioning/Extinction And The Role Of The Amygdala In Human Neuroimaging., Olivia Cook

Electronic Theses and Dissertations

Fear plays a crucial role in survival but can lead to psychological disorders when dysregulated. Fears can be innate due to evolutionary relevance or learned through associative processes, where predictive accuracy of threat is pivotal. Disruptions in fear neurocircuitry contribute to anxiety disorders, characterized by heightened activation and impaired learning. Fear conditioning and extinction paradigms based on classical Pavlovian conditioning have been used to study mechanisms underlying fear learning. Using this experimental model, fear networks in rodents have been described in detail with clear distinction between conditioning and extinction neural functioning. Yet, there is no consensus on the neurobiological processes …

Characterizing The Ethanol Sensitivity Of The Planar Cell Polarity Pathway In Endoderm Morphogenesis And Jaw Development., Raéden Omneil C. C. Rolle Gray

Electronic Theses and Dissertations

Fetal Alcohol Spectrum Disorders (FASD) describes a large range of developmental defects due to prenatal alcohol exposure. It is characterized by neural and facial defects, including jaw hypoplasia. Many factors contribute to the susceptibility of ethanol-induced facial defects, including genetics, yet the genes involved, and the cell events they regulate, are poorly understood. Zebrafish have a large number of tools for genetic manipulation available, share 70% of genes with humans, are fertilized externally and are translucent during embryogenesis, making them great models to study FASD. Previous studies show that two members of the Planar Cell Polarity (PCP) pathway, zebrafish vangl2 …

The Ecology Of Arthropod Rain In A Tropical Forest., Andrew Robert Seiler

Electronic Theses and Dissertations

Tropical forests are structured by complex vertical linkages and nutrient exchanges between canopy and understory habitats. These linkages include the downward flux of organisms, the movement of canopy fauna, and the recycling of nutrients through litter and organic matter deposition. This dissertation investigates arthropod rain and its role in connecting the canopy and forest floor processes in a lowland tropical forest in Panama. Chapter 2 quantifies “arthropod rain”, the fall of canopy arthropods into the understory. Using pan and pole traps, I measured the composition, abundance, and biomass of arthropods falling from the canopy and assessed environmental drivers of the …

Structure And Function Studies On Trna Splicing Endonuclease, Justin G. Underwood

Dissertations and Theses (Open Access)

A subset of eukaryotic pre-tRNAs have introns that must be spliced out to become mature molecules capable of functioning in translation. This essential processing step is performed by tRNA splicing endonuclease (TSEN), a highly conserved heterotetramer with two catalytic and two structural subunits. In addition to this conserved function, archaeal TSEN also processes pre-rRNA and yeast TSEN cleaves some mRNAs that encode mitochondrial proteins to initiate mRNA degradation. Interestingly, single amino acid mutations in TSEN cause the human Mendelian disease pontocerebellar hypoplasia (PCH) by an unknown mechanism. Recently, several groups have determined the structure of human TSEN, revealing similarities and …

Host-Intrinsic Factors Determine Anti-Tumor Efficacy Of Exercise In Pancreatic Ductal Adenocarcinoma, Sumedha Pareek

Dissertations and Theses (Open Access)

Pancreatic Ductal Adenocarcinoma (PDAC) is the third leading cause of cancer-related deaths with a low 5-year relative survival rate of approximately 13.3% for all stages combined. We have previously shown that exercise can improve quality of life and enhance functional capacity among patients with PDAC. Exercise induces a variety of changes in the tumor microenvironment with beneficial effects in several tumor types. However, our understanding of the clinical effects of exercise and the mechanisms that mediate anti-tumor effects are limited in pancreatic cancer.

In this project, using C57BL/6 mice from Taconic Biosciences (Tac) and Jackson Laboratories (Jax), we established a …

A Randomized Controlled Trial Combining House Screening And Insecticide-Treated Nets Reduces Malaria Transmission In Northwestern Ethiopia, Aklilu K. Belay, Abebe Asale, Catherine L. Sole, Abdullahi A. Yusuf, Baldwyn Torto, Zewdu Abro, Menale Kassie, Clifford M. Mutero, David P. Tchouassi

All Peer-Reviewed Publications

House screening (HS) of doors, eaves, and windows using wire-mesh has demonstrated potential in the integrated vector management of malaria. However, limited epidemiological data are available to guide its implementation across different ecological settings. In a 16-month randomized controlled trial (follow-up period) conducted across three agroecological areas (dry mountain, plateau highland, and semi-arid) in Jabi Tehnan district, northwestern Ethiopia, treatment houses were equipped with HS combined with insecticide-treated nets (ITNs), while control houses received ITNs only. The intervention led to a significant 2.3-fold reduction in indoor malaria vector density, the primary entomologic outcome, largely influenced by An. gambiae s.l. mosquitoes. …

The Distribution And Reproductive Success Of The Western Snowy Plover Along The Central And Southern Oregon Coast - 2025, David J. Lauten, Kathleen A. Castelein, Mary Lee, Jessica Burr, Marty R. Mccamant, Eleanor P. Gaines

Institute for Natural Resources Publications

We monitored the distribution, abundance and productivity of the federally threatened Western Snowy Plover (Anarhynchus nivosus nivosus) along the central and south coast of Oregon from 3 April – 10 September 2025. We surveyed and monitored plover activity in a project area that included, from north to south, Sutton Beach, Siltcoos River estuary, the Dunes Overlook, North Tahkenitch Creek, Tenmile Creek, Coos Bay North Spit (CBNS), Bandon Snowy Plover Management Area (SPMA), New River Habitat Restoration Area (HRA) and adjacent lands, and Floras Lake. Our objectives for the project area in 2025 were to: 1) estimate the size of the …

Nutrient Utilization Efficiency And Antioxidant Profile Of Bc2 Abaca (Musa Textilis Née) Hybrids, Roberto Barba Jr, Antonio Lalusin

The Philippine Agricultural Scientist

Abaca (Musa textilis Née) is an important fiber crop widely recognized for its superior tensile strength, yet its productivity remains constrained by nutrient inefficiency, poor cropping management, and climatic stresses under manual production systems. Efficient nutrient utilization and an understanding of antioxidant compositions are practically relevant to the productivity of the abaca fiber crop. However, despite the crop’s economic importance, limited studies have examined nutrient uptake dynamics and internal utilization efficiency related to fiber synthesis. This study aimed to demonstrate the nutrient utilization efficiency and antioxidant profiles of BC₂ abaca hybrids in relation to fiber yield and quality. Fiber …

Prevalence Of Shiga Toxin Producing Escherichia Coli In Illinois Bison Herds, Adam M. Baldocchi

Honors Capstones

Shiga toxin-producing Escherichia coli (STEC) represents an important group of zoonotic pathogens that pose ongoing risks to public health through foodborne outbreaks and environmental transmission. This project evaluated the prevalence and genetic distribution of stx1 and stx2 toxin genes in fecal samples collected from Illinois bison Bison bison) managed under either commercial or preservation conditions. A total of 320 fecal samples were screened for STEC presence by performing enrichment culturing and confirmed by Polymerase Chain Reaction (PCR) for stx1, stx2, and uidA, which confirmed E. coli identity. Of all tested samples, 28.4% were STEC-positive, with stx2 (21.3%) …

Evaluating Metamitron Efficacy For Glyphosate-Resistant Palmer Amaranth (Amaranthus Palmeri) Management In Sugarbeet Across The Central High Plains, Abraham Akuoko

Department of Agronomy and Horticulture: Dissertations, Theses, and Student Research

Herbicide-resistant (HR) Palmer amaranth (Amaranthus palmeri S. Watson) is regarded as one of the most prominent weeds within sugarbeet fields across the Central High Plains, with limited chemical control options. Although a few herbicides are available, their use is restrictive due to crop injury concerns and can only be applied at or after the 2–4 true leaf (TL) growth stage, which will provide no control for already emerged weeds. However, Palmer amaranth often emerges between sugarbeet planting and the 2 TL sugarbeet growth stage. Consequently, as of 2023, there were no herbicide options to control Palmer amaranth in sugarbeet …

Uncovering The Diversity Of Bats In The Mbam Minkom Massif, Cameroon: Insights Into The Importance Of Tropical Inselbergs, Amanda L. Grunwald, Terrence C. Demos, Patrick J. Atagana, Courtney M. Volk, Ara Monadjem, Franck P. Meyo Konoo, Yvette Ngueagni, R. Travis Merrill, Daniel J. Ballhorn, Luis A. Ruedas, Multiple Additional Authors

Biology Faculty Publications and Presentations

We report the results of two expeditions (2019 and 2022) to the Mbam Minkom Massif (Centre Region, Cameroon), focused on an assessment of the montane area's bat fauna. We describe bat species' richness and highlight the incredible diversity and ecological importance of this highly threatened ecosystem. Across both years, we captured a total of 36 bat species representing 21 genera and six families on Mbam Minkom Massif and in the surrounding lowland forest. Our findings include two new species records for Cameroon, and two additional records of the recently described bat, Pseudoromicia mbamminkom. We provide accounts for all captured species, …