Open Access. Powered by Scholars. Published by Universities.®
- Institution
-
- University of Nebraska - Lincoln (32952)
- Utah State University (16178)
- University of Kentucky (15581)
- TÜBİTAK (10887)
- The Texas Medical Center Library (10513)
-
- Department of Primary Industries and Regional Development, Western Australia (6295)
- University of Arkansas, Fayetteville (5477)
- Eastern Illinois University (4790)
- Changsha University of Science and Technology (4759)
- Brigham Young University (4336)
- South Dakota State University (4221)
- Western Kentucky University (4177)
- Old Dominion University (3317)
- Colby College (3263)
- Louisiana State University (2475)
- City University of New York (CUNY) (2460)
- Chulalongkorn University (2353)
- University of South Florida (2239)
- Nova Southeastern University (2224)
- California Polytechnic State University, San Luis Obispo (2151)
- Henry Ford Health (2151)
- Eastern Washington University (2054)
- Wright State University (1987)
- Virginia Commonwealth University (1900)
- WellBeing International (1818)
- University of Texas Rio Grande Valley (1803)
- The University of Southern Mississippi (1781)
- University of Nevada, Las Vegas (1765)
- Morehead State University (1759)
- University of South Carolina (1716)
- Keyword
-
- Humans (7233)
- Western Australia (3849)
- Animals (3354)
- Agricultural newspapers (3000)
- American newspapers (3000)
-
- Central Maine (3000)
- Maine history (3000)
- Popular literature (3000)
- Female (2840)
- 19th century newspapers (2670)
- Agriculture (2375)
- Male (2318)
- Mice (2239)
- National Smokejumper Association (1832)
- Smokejumpers -- United States (1828)
- Smokejumping (1825)
- Wildfire fighters (1825)
- Obituaries (1680)
- Biology (1541)
- Climate change (1406)
- Adult (1283)
- Middle Aged (1201)
- Ecology (1174)
- Nutrition (1153)
- Turkey (1135)
- Conservation (1089)
- Aged (1084)
- Cancer (1061)
- Taxonomy (1037)
- Genetics (1022)
- Publication Year
-
- 2026 (6101)
- 2025 (12463)
- 2024 (13576)
- 2023 (14359)
- 2022 (11983)
-
- 2021 (13444)
- 2020 (13494)
- 2019 (10627)
- 2018 (12525)
- 2017 (11219)
- 2016 (10303)
- 2015 (8768)
- 2014 (7606)
- 2013 (7707)
- 2012 (6439)
- 2011 (5490)
- 2010 (5146)
- 2009 (4545)
- 2008 (3984)
- 2007 (3598)
- 2006 (3149)
- 2005 (3257)
- 2004 (2687)
- 2003 (2563)
- 2002 (2972)
- 2001 (2476)
- 2000 (2418)
- 1999 (2284)
- 1998 (1947)
- 1996 (1670)
- Publication
-
- IGC Proceedings (1977-2023) (9261)
- Faculty, Staff and Student Publications (7585)
- Theses and Dissertations (4980)
- Food and Machinery (4759)
- Specimens by Name (3361)
-
- Turkish Journal of Veterinary & Animal Sciences (3209)
- Electronic Theses and Dissertations (3175)
- All Graduate Theses and Dissertations, Spring 1920 to Summer 2023 (2880)
- Faculty Publications (2620)
- The Waterville Mail (Waterville, Maine) (2161)
- Turkish Journal of Agriculture and Forestry (2161)
- Henry Ford Hospital Medical Journal (2151)
- Turkish Journal of Zoology (2109)
- University of Nebraska-Lincoln Extension: Historical Materials (2063)
- Journal of the Department of Agriculture, Western Australia, Series 4 (1916)
- All Current Publications (1874)
- Biology Faculty Publications (1765)
- Turkish Journal of Botany (1739)
- Graduate Theses and Dissertations (1734)
- Department of Agronomy and Horticulture: Faculty Publications (1713)
- Smokejumper Obituaries (1679)
- Turkish Journal of Biology (1669)
- The Great Lakes Entomologist (1578)
- Biological Sciences Faculty Publications (1570)
- Master's Theses (1565)
- Faculty, Staff and Students Publications (1552)
- Masters Theses (1545)
- The Thai Journal of Pharmaceutical Sciences (1535)
- United States Department of Agriculture Wildlife Services: Staff Publications (1527)
- All Peer-Reviewed Publications (1479)
- Publication Type
Articles 2851 - 2880 of 256516
Full-Text Articles in Entire DC Network
Eeg Studies Of Pre-Stimulus Activity During Turn-Taking In Naturalistic Conversation, Seyedmohamadreza Manzourolajdad
Eeg Studies Of Pre-Stimulus Activity During Turn-Taking In Naturalistic Conversation, Seyedmohamadreza Manzourolajdad
Student Works (2020-2029)
This study integrates conversational analysis principles and neural activity to investigate natural cognition and examine event-related brain changes. A wireless electroencephalography (EEG) device was used in an ecological validity setting to analyse pre-stimulus brain activity preceding conversational turns. This study aims to identify aspects of the conversation that reflect its naturalness in the aspect of listening and the corresponding brain activity by analysing the signals before and after a turn in a conversation. This research contributes to an ecologically valid understanding of natural conversation as a social action that enables seamless communication. Seven Malaysian participants (aged 19–22, M=20.46) engaged in …
Impact Of Human Disturbance On Moth Populations In Ecuador, Gianna Jones, Abbie Miller, Esther Frederickson, Grace Glerum
Impact Of Human Disturbance On Moth Populations In Ecuador, Gianna Jones, Abbie Miller, Esther Frederickson, Grace Glerum
Science Seminar
Habitat disturbance in the temperate zone has been shown to negatively impact moth biodiversity and population size through a reduction in moth food resources and light pollution. Our study sought to understand how human activity impacts moth population numbers and diversity (# unique taxa) in the tropics. Specifically, we sampled moth population and diversity using light traps on two different nights in a disturbed habitat (Mera township, Ecuador) and on two nights at a nearby ecolodge situated in dense tropical forest. Significantly fewer moths were observed during trapping sessions in the township, and many fewer distinct taxa were noted when …
Patterns Of Moth Diversity In Relationship To Human Disturbance And Forest Type, Gianna Jones, Abbie Miller, Esther Frederickson, Grace Glerum
Patterns Of Moth Diversity In Relationship To Human Disturbance And Forest Type, Gianna Jones, Abbie Miller, Esther Frederickson, Grace Glerum
Science Seminar
Moths play a vital role in the health of tropical ecosystems, acting as important pollinators and food resources for a variety of species. Unfortunately, human habitat disturbance has been associated with declines in moth populations and diversity. To explore the impacts of habitat disturbance on taxonomic diversity in the tropics, we sampled moth populations at two different locations in the Pastaza Province (Mera township and an undisturbed forest at Tamandua Ecolodge). Though small in population (
The Impacts Of Wing-Flashing By Northern Mockingbirds On Foraging, Parental Care, And Reproductive Success, Anna Starman, Hayley Ponn
The Impacts Of Wing-Flashing By Northern Mockingbirds On Foraging, Parental Care, And Reproductive Success, Anna Starman, Hayley Ponn
Science Seminar
Foraging efficiency may be enhanced by flashing patches of white wing and tail feathers and has been documented in several avian species. Northern Mockingbirds (Mimus polyglottos, NOMO) exhibit this "wing-flashing" (WF) behavior while foraging, during displays, and in response to predators. In NOMOs, WF has been hypothesized to increase foraging success, but previous findings are inconclusive. To further investigate the biological role(s) of WF behavior in NOMOs, the ventral surface of white primary feathers of male NOMOs were artificially darkened and the foraging and provisioning rates of undarkened (control) males and their mates were compared. While foraging, undarkened males performed …
Foraging Load Size And Activity In Leaf-Cutter Ants In Rural And Urban Ecuador, Natalie Tollison, Anna Starman
Foraging Load Size And Activity In Leaf-Cutter Ants In Rural And Urban Ecuador, Natalie Tollison, Anna Starman
Science Seminar
Leaf cutter ants are important ecosystem engineers in Neotropical forests, moving a significant amount of nutrients from the forest canopy to the soil. We were interested in understanding how time (day vs. night), weather, and level of human disturbance would impact foraging activity in leaf-cutter ants (Atta spp.). To investigate, we sampled activity levels and leaf size along leaf-cutter ant trails in Mera (urban, N=17) and Tamandua (forest, N=27). During the daytime, ants in Mera carried significantly more leaves that were larger in size as well as more total items than did ants in Tamandua. Factors such as the level …
Biodiversity And Diet Patterns: Environmental Impacts On Ecuadorian Birds, Holly Hylton, Fin Bolt, Gracyn Herbst
Biodiversity And Diet Patterns: Environmental Impacts On Ecuadorian Birds, Holly Hylton, Fin Bolt, Gracyn Herbst
Science Seminar
The current biodiversity crisis is of great concern, particularly to bird species in temperate and tropical areas. We examined avian biodiversity patterns in Ecuador, one of the most bird-biodiverse countries in the world (1650+ species). In January 2026, birds were surveyed (visual and auditory) for 30 minutes on consecutive days in 4 different locations that differed in the degree of human development. As expected, species richness was much higher in undisturbed locations than disturbed locations. In addition, our comparison of dietary patterns between sites showed a much higher proportion of frugivorous and insectivorous species in areas with less human disturbance …
Spin-Label Probing Of Gp28 Elucidates Interactions With Lipid Vesicles Using Cw-Epr, Maxwell Sutherland, Binaya Baral, Gary Lorigan
Spin-Label Probing Of Gp28 Elucidates Interactions With Lipid Vesicles Using Cw-Epr, Maxwell Sutherland, Binaya Baral, Gary Lorigan
ONU Student Research Colloquium
The phage protein gp28 is a bacterial membrane lysis protein that functions outside of currently understood canonical pathways for bacterial lysis. Primarily, lysis is done in conjunction with proteins called spanins, however about 15% of gram negative bacteria infecting phages have coding for spanins. This led to the discovery of the disruptins, a class of non-spanin outer membrane disrupting proteins which includes gp28 from the φKT phage. To understand the mechanism in which gp28 disrupts the outer membrane, we employ spin labeling of the protein in its synthesis and create samples of artificial membranes. Using electron paramagnetic resonance (EPR), we …
Cost Analysis Formulation For Pv–Evcs–Dstatcom Integrated Distribution Systems Using Enhanced Hunter–Prey Optimization, Pappu Soundarya Lahari, Varaprasad Janamala
Cost Analysis Formulation For Pv–Evcs–Dstatcom Integrated Distribution Systems Using Enhanced Hunter–Prey Optimization, Pappu Soundarya Lahari, Varaprasad Janamala
Mansoura Engineering Journal
With the rapid and significant growth of Electric Vehicles (EVs) and Distributed Generation (DGs), such as Photovoltaic (PV) deployment, in the distribution system, it is essential to address the challenges of rising power losses, voltage fluctuations, and reactive power imbalances. Optimal DSTATCOM placement in PV-EV integrated systems to mitigate power quality issues is an effective solution. It is thus necessary to evaluate the economic considerations of such heavily compensated networks. This study proposes Enhanced Hunter-Prey Optimization (EHPO) to assess the net savings of the PV-EVCS-DSTATCOM integrated IEEE-33,69, and 118 bus distribution networks in both single and multi-objective modes. The multi-objective …
Effects Of Limb Dominance On Dopaminergic Neurodegeneration In A 6-Ohda Rat Model Of Parkinson’S Disease Assessed By Immunoblotting, Jasin Aziz Porshia, Deanna Chaialee, Dipesh Pokharel, Kala Venkiteswaran, Thyagarajan Subramanian, Dilshan Beligala
Effects Of Limb Dominance On Dopaminergic Neurodegeneration In A 6-Ohda Rat Model Of Parkinson’S Disease Assessed By Immunoblotting, Jasin Aziz Porshia, Deanna Chaialee, Dipesh Pokharel, Kala Venkiteswaran, Thyagarajan Subramanian, Dilshan Beligala
ONU Student Research Colloquium
Effects of Limb Dominance on Dopaminergic Neurodegeneration in a 6-OHDA Rat Model of Parkinson’s Disease Assessed by Immunoblotting
Jasin Porshiaa , Deanna Chaialeea , Dipesh Pokharelb,c , Kala Venkiteswaranb, c, d , Thyagarajan Subramanianb, c, d, Dilshan Beligalaa
aDepartment of Biological Sciences, Ohio Northern University, Ada, OH, USA
bDepartment of Neurosciences and Psychiatry, The University of Toledo College of Medicine and Life Sciences, Toledo, OH, USA
cDepartment of Neurology, The University of Toledo College of Medicine and Life Sciences, Toledo, OH, USA
dDepartment of Neurology, Howard University, Washington, DC, …
A Single Administration Of Psilocybin Is Ineffective In Reversing Ptsd-Like Sequelae In A Rat Model Of Stress-Enhanced Fear Learning, Kylie M. King, Marisa J. Savini, Noelle M. Molnar, Evelynn J. Schneider, Savannah E. Straub, Joe Parker, Lillianna P. Puppel, Aleece K. Al-Olimat, Allison M. Bach, Phillip R. Zoladz
A Single Administration Of Psilocybin Is Ineffective In Reversing Ptsd-Like Sequelae In A Rat Model Of Stress-Enhanced Fear Learning, Kylie M. King, Marisa J. Savini, Noelle M. Molnar, Evelynn J. Schneider, Savannah E. Straub, Joe Parker, Lillianna P. Puppel, Aleece K. Al-Olimat, Allison M. Bach, Phillip R. Zoladz
ONU Student Research Colloquium
Single treatments with psychedelics produce rapid, long-lasting antidepressant effects. Psychedelics may also exert anxiolytic effects and be useful in treating more complex psychiatric conditions, such as PTSD. However, less is known about the impact of these agents on PTSD-related symptoms. Thus, we aimed to determine whether a single administration of psilocybin could reverse PTSD-like sequelae induced by stress-enhanced fear learning in rats. Sprague-Dawley rats were placed in Context A (circular, white conditioning box) and exposed to several uncontrollable footshocks (Stress) or no footshocks (No Stress). The next day, the rats were placed in Context B (square conditioning box with clear …
Psilocybin And The Related Tryptamine, Norbaeocystin, Exert Acute Anxiogenic Effects That Depend On Sex, Marisa J. Savini, Kylie M. King, Noelle M. Molnar, Evelynn J. Schneider, Savannah E. Straub, Joe Parker, Lillianna P. Puppel, Aleece K. Al-Olimat, Allison M. Bach, Andrew Jones, Phillip R. Zoladz
Psilocybin And The Related Tryptamine, Norbaeocystin, Exert Acute Anxiogenic Effects That Depend On Sex, Marisa J. Savini, Kylie M. King, Noelle M. Molnar, Evelynn J. Schneider, Savannah E. Straub, Joe Parker, Lillianna P. Puppel, Aleece K. Al-Olimat, Allison M. Bach, Andrew Jones, Phillip R. Zoladz
ONU Student Research Colloquium
Single treatments with psychedelics have demonstrated rapid, long-lasting antidepressant effects. However, psychedelics often produce unfavorable psychoactive effects that could worsen existing psychological distress. Thus, we compared the effects of psilocybin and the related tryptamine, norbaeocystin, on anxiety-like behavior in male and female rats. In Experiment 1, rats were treated with 1 mg/kg psilocybin (PSIL), 1 mg/kg norbaeocystin (NOR), or vehicle 30 min before a 5-min trial on an elevated plus maze (EPM) or in an open field test (OFT). On the EPM, PSIL led to decreased open arm time and fewer arm entries in males and females. NOR led to …
Impact Of Caffeine On Participant Memory For A Stressful Experience And The Development Of Intrusive Memories, Jaycee L. Kirkland, Kaylina R. Mcclenen, Natalina E. Porter, Sarah M. Wood, Julia Gross, Madilyn E. Paphanchith, Kelsey M. Siereveld, Jasmine Ic Ifeakanwa, Caeden M. Gurganus, Koen N. Suzelis, Aiden J. Farrell, Boyd R. Rorabaugh, Phillip R. Zoladz
Impact Of Caffeine On Participant Memory For A Stressful Experience And The Development Of Intrusive Memories, Jaycee L. Kirkland, Kaylina R. Mcclenen, Natalina E. Porter, Sarah M. Wood, Julia Gross, Madilyn E. Paphanchith, Kelsey M. Siereveld, Jasmine Ic Ifeakanwa, Caeden M. Gurganus, Koen N. Suzelis, Aiden J. Farrell, Boyd R. Rorabaugh, Phillip R. Zoladz
ONU Student Research Colloquium
Most individuals consume caffeine on a daily basis. Research has shown that caffeine stimulates the release of glucocorticoids and catecholamines and can enhance cognition. Caffeine also amplifies stress-induced increases in arousal and aggravates PTSD-like symptoms. Thus, we examined the impact of caffeine on memory for a stressful experience and intrusive memories related to that experience. Undergraduate students ingested caffeine or a placebo. Thirty minutes later, they were exposed to the Trier Social Stress Test (TSST; stress condition) or friendly-TSST (f-TSST; control condition), both of which were designed to enable participant memory for the experiences to be quantified. In each condition, …
Role Of Cb1 Receptors In Mediating Thermal Pain In Male And Female Mice, Jessica Acheampong, Sarah Seeley, Manoranjan S. Dsouza
Role Of Cb1 Receptors In Mediating Thermal Pain In Male And Female Mice, Jessica Acheampong, Sarah Seeley, Manoranjan S. Dsouza
ONU Student Research Colloquium
Pain is responsible for significant morbidity and mortality in the United States and all over the world. CB1 cannabinoid receptors have been reported to play a role in pain. Also, more recently sex-dependent behavioral differences after CB1 receptor activation have been reported. However, the sex-dependent effects of CB1 receptor activation on thermal pain have not been systematically assessed. This project will address this gap in knowledge. The study will use adult male and female C57BL6 mice. CB1 receptors will be activated using the synthetic cannabinoid WIN 55212. Thermal pain will be assessed using the hot plate method. Data for the …
Program And Proceedings, The Nebraska Academy Of Sciences 1880–2026: 146th Anniversary Year, One Hundred-Thirty-Sixth Annual Meeting
Nebraska Academy of Sciences: Programs and Proceedings
Program and abstracts of the proceedings for the Nebraska Academy of Sciences 136th annual meeting, 2025
Sessions
Aeronautics and Space Science
Anthropology
Biological and Medical Sciences
Earth Sciences
Ecology, Sustainability, and Environmental Science
Physics and Engineering
General Poster Session
2026 Maiben Lecture: Shifting Extremes: Understanding Nebraska’s Changing Climate and Preparing for What Lies Ahead, Deborah Bathke
2026 Friends of Science Awards: Julie Shaffer and Irina Filina
2026 C. Bertrand and Marian Othmer Schultz Colleaguate Schoalrship Award: Piper Ryschon and Bryce Reeson
In Memoriam: Paul Royster
Evaluating Drug Use Through Examination Of Local Water Sources: Drug Concentrations Within Biota Systems, Madeleine Freyhof
Evaluating Drug Use Through Examination Of Local Water Sources: Drug Concentrations Within Biota Systems, Madeleine Freyhof
Honors Projects
Understanding drug usage based on drug concentrations found within biota samples grown in different concentrations of cocaine and benzoylecgonine. Drug policy then can be potentially based on how drug concentrations display drug usage for a specific community.
Pepper Spray Exposure And The Effect On Dna Profiling Of Blood, Brandon Schmakel
Pepper Spray Exposure And The Effect On Dna Profiling Of Blood, Brandon Schmakel
Honors Projects
Pepper spray is a common self defense tool used in both law enforcement and civilian settings, with the goal of incapacitating the sprayed individual. In real casework where pepper spray was used, a red-brown stain which tested positive presumptively for blood provided no DNA profile after further testing six months later. A previous graduate student, Emma Crawn, attempted to emulate these casework conditions and instead achieved a DNA profile with slight indications of inhibition or degradation. Further analysis of active pepper spray ingredients such as Oleoresin Capsicum (OC) and Chloroacetophenone (CN) reveals that there are observed reactions, such as oxidation, …
Ethnicity, Culture, And The Epidemiology Of Eating Disorders, Rebecca Atwell
Ethnicity, Culture, And The Epidemiology Of Eating Disorders, Rebecca Atwell
Honors Theses
This systematic literature review addresses the research question: How does culture affect eating disorders? It examines the role of ethnicity and culture in shaping the prevalence, symptom presentation, and treatment of eating disorders across diverse populations. Although eating disorders have traditionally been studied in Western, predominantly White populations, growing evidence suggests that cultural norms, ethnic identity, globalization, and exposure to Western ideals significantly influence both the development and expression of disordered eating behaviors. Twenty peer-reviewed studies published between 2000 and 2024 were included. These studies were identified through systematic searches of PubMed, Scopus, Web of Science, and PsycINFO and selected …
Cultivating Curiosity Across Academic Audiences: Biology And Evidence-Based Science Communication, Nathan D. Forbes
Cultivating Curiosity Across Academic Audiences: Biology And Evidence-Based Science Communication, Nathan D. Forbes
Whittier Scholars Program
Effective Science Communicators must speak to a variety of audiences, with varying quantities of prior interest and qualities of background knowledge. The purpose of this paper was to engage differing audiences in scientific learning. This was done through a hypothetical newsletter made up for four different segments exploring a variety of topics in biology. Each segment intends to speak to a different audience with a different level of interest and/or educational level. Simplifying or analogizing without sacrificing the statistical basis of this project was of paramount importance. In the two segments targeted towards younger audiences, the primary focus was on …
A Continuous Viral Vaccine Biomanufacturing Platform Utilizing Multiple Bioreactor Configurations, Justin Sargunas, Bradley Priem, Dylan Carman, Taravat Sarvari, Natalie Nold, Vaishali Sharma, Andrew Pekosz, Caryn Heldt, Michael Betenbaugh
A Continuous Viral Vaccine Biomanufacturing Platform Utilizing Multiple Bioreactor Configurations, Justin Sargunas, Bradley Priem, Dylan Carman, Taravat Sarvari, Natalie Nold, Vaishali Sharma, Andrew Pekosz, Caryn Heldt, Michael Betenbaugh
Michigan Tech Publications
Scalable, continuous biomanufacturing processes have grown in importance to meet demand for smaller bioreactor sizes, lowered production costs, and improved quality attribute consistency. The Sf9/recombinant baculovirus (rBV) expression system demonstrates promise for virus-like particle (VLP) vaccine and gene therapy production. Here, we present a continuous rBV platform integrating an infection plug flow reactor (PFR) between stirred tank growth (gCSTR) and production (pCSTR) bioreactors. Cell expansion in the gCSTR included a ramp-up stage followed by continuous growth, reaching a steady state of 5×10 cells/mL and >90% viability. Péclet number-fit tracer studies confirmed near-ideal plug flow in the PFR, yielding a 10 …
From Bench To Bedside: Unraveling The Role Of Sarm1 In Chronic Human Neurodegenerative Disease, Caitlin Dingwall
From Bench To Bedside: Unraveling The Role Of Sarm1 In Chronic Human Neurodegenerative Disease, Caitlin Dingwall
Arts & Sciences Graduate Student Theses and Dissertations
Axon degeneration (AxD) is an early and often causative event in many neurodegenerative diseases, yet no treatments exist to halt the breakdown of axons. In healthy axons, the axon survival factor NMNAT2 inhibits SARM1, the central executioner of programmed axon degeneration. NMNAT2 is a highly labile protein produced in the soma and trafficked into the axon. Nerve injury blocks axonal transport and leads to rapid depletion of axonal NMNAT2, causing NMN buildup and NAD+ loss. Recent breakthroughs led to the discovery that SARM1 is activated by an increase in the NMN to NAD+ ratio. While the SARM1 axon degeneration pathway …
How Pollinator Populations Can Impact Chronic Disease Risk, Kylee Cubbison
How Pollinator Populations Can Impact Chronic Disease Risk, Kylee Cubbison
Honors Projects
This project investigates how pollinator populations can impact chronic disease risk. Pollinator populations are declining, which can have serious implications for human health. Declining pollinator populations can limit healthy food production and affordability. Poor nutrition is a major risk factor for most chronic diseases. Less healthy food available for people to consume can negatively impact diets and increase the risk of developing chronic diseases. This project aims to address a potential gap in research existing on this specific topic regarding pollinator populations and human chronic disease risk. A brochure targeted towards educating the general public on this topic was created …
Development Of A Preclinical Model That Can Be Used To Test Novel Therapeutics For The Treatment Of Mild And Moderate Traumatic Brain Injury, Hayden Anderson
Development Of A Preclinical Model That Can Be Used To Test Novel Therapeutics For The Treatment Of Mild And Moderate Traumatic Brain Injury, Hayden Anderson
Honors Theses
Traumatic Brain Injury (TBI) occurs when a foreign object induces damage to the skull and brain through a forceful blow or whiplash. It is one of the most frequent injuries in the United States, with approximately 250,000 cases of different levels occurring annually. It is well known that severe TBIs can result in persistent physical, cognitive, and socioeconomic consequences and the timing of treatment following this injury can play a critical role in the ultimate outcome. It would be beneficial to develop a safe therapeutic that could be administered rapidly after impact and improve the recovery of the patient. However, …
The Pam-1 Aminopeptidase Does Not Protect Against Ptl-1 Mediated Neurodegeneration In C. Elegans., Ethan E. Schuff
The Pam-1 Aminopeptidase Does Not Protect Against Ptl-1 Mediated Neurodegeneration In C. Elegans., Ethan E. Schuff
Honors College Theses
Debilitating neurodegenerative conditions are increasingly prevalent in our aging population, yet treatment options remain limited. Though neurodegenerative diseases vary in pathophysiology and clinical manifestations, these diseases are related to one another in that many involve misfolded proteins. Tau is a member of the microtubule-stabilizing MAPT/MAP2/MAP4 family, and misfolded tau proteins form the neurotoxic aggregates called neurofibrillary tangles (NFTs) found in the brains of patients with Alzheimer's disease and other neurodegenerative diseases. Designing a study to elucidate the neurotoxic role of tau is difficult because other MAPs may have compensatory mechanisms which confound study data. Caenorhabditis elegans (C. elegans) …
Multi-Strain Assessment Of Quorum Sensing In Chlamydomonas Reinhardtii, Jacqueline Krueger
Multi-Strain Assessment Of Quorum Sensing In Chlamydomonas Reinhardtii, Jacqueline Krueger
Ocean Engineering and Marine Sciences Student Publications
Quorum sensing (QS) allows microbial populations to coordinate phenotypic switching, selecting for specific behaviors that are only beneficial when expressed at high cell densities (HCD, >106 cells/mL) rather than low cell densities (LCD, < 106 cells/mL)
Role Of Rpm-1 In A C. Elegans Apoe4 Alzheimer’S Disease Model, Lucille Mcdonald
Role Of Rpm-1 In A C. Elegans Apoe4 Alzheimer’S Disease Model, Lucille Mcdonald
Biomedical Engineering and Sciences Student Publications
Alzheimer’s Disease (AD) is characterized by the aggregation of β-amyloid plaques. The ε4 allele of APOE (APOE4) is linked to increased plaque formation in AD. Therefore, identifying genetic modifiers of APOE4 could present novel drug targets for AD treatment.
Assessing Developmental Neurotoxicity Due To Pyrethroid Insecticide Exposure In C. Elegans, Katharine Boyd, Timothy A. Crombie
Assessing Developmental Neurotoxicity Due To Pyrethroid Insecticide Exposure In C. Elegans, Katharine Boyd, Timothy A. Crombie
Biomedical Engineering and Sciences Student Publications
Pyrethroids are a type of insecticide widely used in agriculture and public health programs. These insecticides disrupt neuronal signaling in target insects through voltage-gated sodium channels and have been linked to cardiovascular and neurological disease in humans.The nervous system of the nematode Caenorhabditis elegans is fully mapped, and specific behavioral circuits can be tested, making it a powerful model for studying neurotoxicity. Because the primary target of pyrethroids is not conserved in C. elegans, secondary mechanisms of pyrethroid neurotoxicity can be identified by testing whether specific behavioral circuits are affected.
Assessment Of Goose-Beaked Whale Responsesto Mid-Frequency Active Sonar Usinga Hierarchical Hidden Markov Model, Stacy L. De Ruiter, Erin A. Falcone, Shannon N. Coates, Brenda K. Rone, David A. Sweeney, Karin A. Dolan, Susan M. Jarvis, Russel D. Andrews, Stephanie L. Watwood, Gregory S. Schorr
Assessment Of Goose-Beaked Whale Responsesto Mid-Frequency Active Sonar Usinga Hierarchical Hidden Markov Model, Stacy L. De Ruiter, Erin A. Falcone, Shannon N. Coates, Brenda K. Rone, David A. Sweeney, Karin A. Dolan, Susan M. Jarvis, Russel D. Andrews, Stephanie L. Watwood, Gregory S. Schorr
University Faculty Publications and Creative Works
Background
Acoustic disturbance is increasingly recognized as an ecological concern, particularly at sea. In light of marine mammal stranding events associated with use of naval mid-frequency active sonar (MFAS), which often involve goose-beaked whales (Ziphius cavirostris), research has sought to detect and characterize Ziphius behavioral responses to MFAS.
Methods
We deployed Sound and Motion Recording and Telemetry (SMRT) tags on 13 Ziphius in the Southern California Bight. The study area includes the United States Navy’s Southern California Anti-submarine Warfare Range (SOAR), and deployments overlapped temporally with training exercises including MFAS use. We used hierarchical hidden Markov models (HHMMs), which provided …
Phenotype Variations Among Chlamydomonas Reinhardtii Under Quorum-Sensing Conditions, Marcel Pedrosa
Phenotype Variations Among Chlamydomonas Reinhardtii Under Quorum-Sensing Conditions, Marcel Pedrosa
Biomedical Engineering and Sciences Student Publications
Quorum sensing (QS) is a cell-to-cell communication system that allows unicellular microorganisms like the eukaryote C. reinhardtii to regulate phenotypic switching as a function of cell density due to the accumulation of signaling molecules. The goal of this study is to evaluate whether QS in C. reinhardtii is regulated by nutrient availability. We propose that in a nutrient-limited environment (low nitrogen TAP (N-TAP)), cells of C. reinhardtii (cc124) would adjust their motility-driven dispersion of cells and upregulate chlorophyll and carotenoid production per cell.
Anterior Cruciate Ligament (Acl) Injuries In Female Athletes: Implications For Prevention And Rehabilitation, Natalie Amm
Anterior Cruciate Ligament (Acl) Injuries In Female Athletes: Implications For Prevention And Rehabilitation, Natalie Amm
Honors Theses
Anterior cruciate ligament (ACL) injuries are among the most common lower limb injuries and pose significant physical, psychological, and long-term functional challenges for athletes. Additionally, research has suggested that females are up to eight times more likely to experience an ACL injury than their male counterparts. This increased risk is multifactorial with risks including anatomical structure, neuromuscular control, strength deficits, and hormonal fluctuations. However, the elevated risk of ACL injuries in female athletes may not solely be caused by biological differences, but also due to training programs and sports being designed around male athletes. This pushes us to change the …
High Performance Ae-Cnn Model Enhanced Via Gaussian Augmentation For Rssi-Dependent Indoor Positioning In Wireless Sensor Networks, Kahlaa K. Al-Nassrawy, Ghaidaa A Al-Sultany
High Performance Ae-Cnn Model Enhanced Via Gaussian Augmentation For Rssi-Dependent Indoor Positioning In Wireless Sensor Networks, Kahlaa K. Al-Nassrawy, Ghaidaa A Al-Sultany
Karbala International Journal of Modern Science
Precise indoor positioning system remains a significant challenge within Wireless Sensor Networks (WSNs) due to the instability and noise sensitivity of Received Signal Strength Indicator (RSSI) data. This paper proposes an advanced hybrid deep learning framework designed for 2D indoor localization, utilizing RSSI measurements to predict human or object position. Furthermore, to enhance the robustness of the model against signal variance and promote its generalization capability under this uncertainty, a data augmentation strategy is applied using three methods: Gaussian Noise Injection (GNI), Gaussian Mixture Model (GMM), and Bayesian Gaussian Mixture Model (BGMM). The purpose of data augmentation is to simulate …