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Novel Oral Delivery System Using Modified Inulin For Enhanced Liver Cancer Therapy, Sung-Ling Tang, Yu-Ju Lai, Wei-Cheng Lin, Meng-Yi Bai, Yu-Chi Wang

Journal of Food and Drug Analysis

Hepatocellular carcinoma (HCC) remains a leading cause of cancer-related deaths worldwide. Although advanced oral anticancer drugs, such as sorafenib and lenvatinib, are available for treating HCC, their effectiveness is limited by significant side effects and the requirement for optimal liver function, restricting their broader use. Furthermore, these drugs cannot be used in combination, leading to suboptimal treatment outcomes. This study introduces a novel therapeutic approach by repurposing two existing drugs, niclosamide and disulfiram, as a combination therapy to treat HCC. Despite their known anticancer properties, these drugs face challenges such as high lipophilicity and a significant first-pass effect, resulting in …

Effect Of Cosmetic Whitening Ingredients’ Lipophilicity On Melanocyte Cytotoxicity: A Systematic Review, Lord Sam B. Liston, Zach Uriel Cabije, Enrico John Belleza, Catherine Ortega, Mark Niño Melgo, Vanbeth Camson, Sabrina Dahlizar, Pajaree Sakdiset, Gea Abigail Ecoy, Gerard Lee See, Florencio Jr. Arce

Journal of Food and Drug Analysis

Tyrosinase is an enzyme involved in the early stages of melanin synthesis. Melanin, which gives skin its pigment, is the most targeted molecule in the development of skin-whitening cosmetic products. Consequential risks of chemically induced skin diseases are associated with the usage of skin-whitening products that contain tyrosinase-inhibiting compounds. Currently, products containing tyrosinase inhibitors on the market lack collective analysis of their toxicity on melanocytes. Moreover, national regulatory agencies (e.g., FDA) place the burden of ensuring the safety of whitening products on manufacturers, risking bias and selective reporting. In fact, the ASEAN Cosmetic Directive does not include more than half …

The Protective Potential Of Intestinal Bifidobacterium-Derived Extracellular Vesicles With Unique Lipid Composition Against Blue Light-Induced Damage In Retinal Cells, Wei-Hsuan Hsu, Pin-Hsuan Su, Hao-Yuan Chien, Tzu-Ming Pan, Bao-Hong Lee

Journal of Food and Drug Analysis

Bifidobacterium longum is a probiotic that resides in the intestine, and extracellular vesicles (EVs) released by microorganisms have garnered attention in recent years for their role in regulating host health. This study found that triacylglycerol, cholesteryl esters, and free fatty acid (18:0 and 16:0) are primarily composed of lipids in B. longum-derived EVs by lipidomics assay. Such lipid composition facilitates the entry of EVs into ARPE-19 cells and protects the cells from oxidative death induced by blue light exposure. Transcriptomic analysis revealed that treatment with B. longum-derived EVs can regulate phosphoinositide 3-kinase and mTOR, thereby enhancing the survival …

Systematic Verification Of Saliva-Based Biosignatures For Oral Cancer Via Targeted Metabolomics, Ya-Ju Hsieh, Yu Chang, Chi Yang, Nai Hsuan Teng, Jau-Song Yu, Kai-Ping Chang, Wen-Chen Chen, Lichieh Julie Chu, Yi-Ting Chen

Journal of Food and Drug Analysis

Oral squamous cell carcinoma (OSCC) remains a major global health challenge, and early detection is essential for improving patient outcomes. To identify reliable salivary biomarkers, we performed a targeted metabolomics study using ¹³C₂/¹²C₂-dansylation, integrating candidate metabolites from published OSCC metabolomics datasets and systematically verifying them through LC-MRM-MS. A panel of 26 metabolites was quantified in saliva samples from 299 subjects, including healthy controls (n = 98), oral potentially malignant disorders (OPMD I, n = 50; OPMD II, n = 53), and OSCC patients (n = 98). Among these, cadaverine, N-acetylcadaverine, choline, glycine, and …

Phthalate Exposure And Lipid Disruption In Taiwanese Children: Insights From Serum Lipidomic Approach, Tzu-Hsin Yen, Wei-Chen Tseng, Sheng-Han Lee, Zhi-Yi Du, Wan-Yu Lin, Mei-Huei Chen, Ching-Chun Lin, Ching-Chun Lin, Hui-Ju Wen, Hao-Jan Liang, Yue-Leon Guo, Pau-Chung Chen, Ching-Yu Lin

Journal of Food and Drug Analysis

Phthalates are ubiquitous environmental contaminants that raise particular concern for children, who generally experience higher exposure levels and are more susceptible to environmental pollutants. To understand potential molecular mechanisms, we conducted a cross-sectional study of 256 Taiwanese children aged 8–10 years from two population-based cohorts: the Taiwan Birth Panel Study and the Taiwan Early-Life Cohort. Serum phosphocholine-containing lipids were profiled by liquid chromatography coupled with triple quadrupole mass spectrometry and associated with urinary levels of 12 phthalate metabolites. Multiple linear regression models, adjusted for demographic and socioeconomic factors, revealed that mono-(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP), an oxidative metabolite of di(2-ethylhexyl) phthalate (DEHP), …

Applications Of Nuclear Magnetic Resonance Spectroscopy In Pediatric Clinical Metabolomics: From Research To Future Perspectives, Chieh-Ni Kuo, Meng-Han Chiang, Hsien-Ju Lee, Yu-Ying Yu, Eric Yi-Liang Shen, Chih-Yung Chiu

Journal of Food and Drug Analysis

Metabolomics studies small-molecule metabolites to provide insights into health and disease, supporting early diagnosis and personalized medicine. Advances in mass spectrometry and nuclear magnetic resonance (NMR) have expanded its use in metabolic, cancer, and cardiovascular diseases. In pediatrics, high-resolution NMR metabolomics has been instrumental in identifying age-related metabolic changes during early childhood and their associations with growth, nutrition, and disease risk. However, a comprehensive review of its clinical applications and future potential remains limited. This review highlights how utilizing specific NMR pulse sequences, such as CPMG and NOESY, allows for precise and non-destructive metabolic profiling of diverse biofluids, supported by …

The Evolution Of Desi-Msi: A Comprehensive Look At Preprocessing And Quantification Strategies For Metabolomics, Cheng-Hung Yang, Hung-Yao Ho, Chen-Yu Chang, Mei-Ling Cheng

Journal of Food and Drug Analysis

Mass spectrometry imaging (MSI) has become an indispensable tool in metabolomics for visualizing the spatial distribution of biomolecules within tissues. Due to its direct, ambient analysis capability, desorption electrospray ionization (DESI-MSI) has evolved from a rapid screening tool into a precise and reliable quantitative platform. We delve into its technical principles and particularly review the criticality of sample preprocessing, highlighting the paradigm shift from a "no-preprocessing" approach to one of "optimized preprocessing." The paper details how factors like sample preservation, choice of embedding agents, washing, drying, and on-tissue chemical derivatization all impact data quality. We also discuss how the addition …

Advanced Technologies Of Single-Cell Metabolomics Unveiling Cellular Metabolic Heterogeneity For Biological And Biomedical Research, Shang-Che Kuo, Ting-Wei Tsao, I-Fan Wang, Ying-Lan Chen

Journal of Food and Drug Analysis

Metabolomics provides direct insights into cellular physiology, yet it faces greater analytical challenges compared to genomics and transcriptomics due to the chemical diversity, instability, and environmental sensitivity of metabolites. Conventional bulk metabolomics averages signals across cell populations, thereby masking cellular heterogeneity critical for understanding disease mechanisms. Recent breakthroughs in single-cell metabolomics (SCM), driven by advances in mass spectrometry, microfluidics, isotope tracing, and spatial omics, have enabled the detection of metabolic diversity at unprecedented resolution. SCM has uncovered cell-type-specific biomarkers, revealed metabolic reprogramming in cancer and immunity and revealed disease progression. These studies highlight SCM’s transformative potential in biomarker discovery, clinical …

Metabolomics Of Per- And Polyfluoroalkyl Substances (Pfas) Exposure: Advances In Lc-Ms Technology And Applications, Yu-Meng Wang, Pei-Chen Lin, Yu-Da Zheng, Pin-Shiuan Wu, Kuo-Tai Hua, Sung-Fang Chen

Journal of Food and Drug Analysis

Per- and polyfluoroalkyl substances (PFAS) are a class of synthetic chemicals known for their high stability and bioaccumulation potential, leading to their widespread presence in the environment and human tissues. Exposure to PFAS has been associated with significant health concerns, including neurotoxicity, hepatotoxicity, and metabolic disturbances. Liquid chromatography–mass spectrometry (LC-MS) based metabolomics has emerged as a powerful and central tool for PFAS research, enabling the comprehensive analysis of metabolic changes induced by exposure. This review provides a critical summary of the applications of LC-MS metabolomics in both clinical studies and various experimental models, including in vivo models (mice) and in …

Recent Advances In Sustainable Production Of Enriched Chicken Eggs: A Mini Review, Karim El-Sabrout, Ayman Abd El-Aziz

Jurnal Ilmu Ternak Universitas Padjadjaran

Enriched or “designer” chicken eggs have emerged as an important category of functional foods aimed at improving human nutrition through dietary manipulation of laying hens. This mini-review summarizes recent advances in egg enrichment strategies, focusing on omega-3 fatty acids, vitamins, minerals, and antioxidant compounds. Omega-3 enrichment remains the most widely adopted approach, achieved through supplementation with flaxseed, fish oil, or microalgae, resulting in significant increases in eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in egg yolk. Multi-nutrient enrichment, including selenium, vitamin E, and carotenoids, has also gained attention due to its potential in enhancing antioxidant capacity and health of hens …

Optimization Of Day-Old Chick (Doc) Parent Stock (Ps) Sales Allocation Using Mixed-Integer Linear Programming (Milp) And Ahp–Topsis: A Case Study Of A Breeding Company In Pangandaran Regency, Mutia Febiani, Achmad Firman, Andre Rivianda Daud

Jurnal Ilmu Ternak Universitas Padjadjaran

The poultry industry requires reliable Parent Stock (PS) output to maintain the continuity of broiler production systems. Breeding companies face operational and financial challenges in allocating Day Old Chick (DOC) Parent Stock (PS) sales between internal and external markets due to uncertainty in supply chain planning and market demand (Solano-Blanco et al., 2023). This study aimed to optimize DOC PS sales allocation using Mixed-Integer Linear Programming (MILP) and prioritize strategic allocation alternatives using the Analytic Hierarchy Process (AHP) combined with the Technique for Order Preference by Similarity to Ideal Solution (TOPSIS). Optimization results show that the maximum profit is achieved …

Effect Of Dietary Onion Peel Powder (Allium Cepa L.) As A Feed Additive On Production Performance In Broiler, Della Ariesba Putri Dulia, Edhy Sudjarwo, Osfar Sjofjan

Jurnal Ilmu Ternak Universitas Padjadjaran

This study aims to evaluate the use of onion peel powder (Allium cepa L) as a feed additive on feed intake, weight gain, Feed Conversion Ratio (FCR), Production Index, and Income Over Feed Cost (IOFC) in broilers. A total of 144 Lohmann strain broiler (unsexed) were treated from 1 to 35 days of age. There were 6 treatments with 4 replicates, consisting of 24 experimental cages, each filled 6 broilers. The experimental design used completely randomized design (CRD). The treatment groups were as follows: basal feed without antibiotics (P0-), basal feed + 0.1% antibiotics (zinc bacitracin) (P0+), basal feed + …

Effect Of Gowok (Syzygium Polycephalum) Fortification On The Physical Properties And Color Of Goat Milk Yogurt, Siti Rahmawati Zulaikhah, Triana Setyawardani, Juni Sumarmono

Jurnal Ilmu Ternak Universitas Padjadjaran

This study aimed to determine the effect of adding parts of gowok fruit (Syzygium polycephalum) on the physical properties of goat’s milk yogurt. A completely randomized design was applied with treatments consisting of fruit parts (rind, flesh of fruit, and whole seedless fruit) and addition levels (1, 2, and 3%) with three replications. Data were analyzed using analysis of variance followed by Duncan’s multiple range test (DMRT). The results showed that gowok addition had a significant effect (P<0.05) on viscosity, syneresis, and color parameters, but no significant effect (P>0.05) on firmness and work of penetration. Yogurt viscosity ranged from 349.33 to 825 mPa·s and decreased with increasing gowok levels, while …

Bibliometric Analysis Of Applications And Research Trends On Whole Milk In Food Science, Nautus Stivano Dalle, Juni Sumarmono

Jurnal Ilmu Ternak Universitas Padjadjaran

This study maps the scientific landscape and research trends on whole milk in food science using a bibliometric approach. Data were collected from Google Scholar via Publish or Perish 8 (2020–2025) using the keyword "whole milk," yielding 291 documents after applying inclusion criteria. Descriptive and visual analyses were performed using VOSviewer and the Bibliometrix package to identify publication trends, collaboration networks, and dominant themes through co-authorship and keyword co-occurrence analyses. Results revealed fluctuating publication patterns, peaking in 2021 (60 articles) and declining in 2025 (41 articles). Keyword mapping identified four major clusters: microbiological characterization and probiotic potential, milk bioactive and …

Physicochemical, Emulsion Stability, And Microbiological Changes Of Light Mayonnaise Containing Soy Protein During Storage, Rifka Anindita Putri, Herly Evanuarini, Premy Puspitawati Rahayu, Khothibul Umam Al Awwaly, Veronica Margareta Ani Nugiartiningsih

Jurnal Ilmu Ternak Universitas Padjadjaran

Light mayonnaise is a low-fat emulsion product that is susceptible to changes in viscosity, emulsion instability, and chemical quality degradation during storage. The addition of functional additives such as soy protein is commonly applied to support product quality. This study aimed to evaluate the physicochemical properties, emulsion stability, and microbiological quality of light mayonnaise containing 1.5% soy protein during storage for 0, 5, 10, and 15 days. The parameters analyzed included viscosity, pH value, emulsion stability, peroxide value, emulsion droplets, and total plate count (TPC). The study was conducted using four storage treatments with five replicates, applying a completely randomized …

Prediction Of Fermentation Parameters During Solid-State Fermentation Of Lemongrass Feedstuffs Using Nirs Combined With Spectral Correction Techniques, Alis Syarmalis, Agus Arip Munawar, Indra Wahyudi, Zulfikar Amir, Samadi Samadi

Jurnal Ilmu Ternak Universitas Padjadjaran

Lignocellulosic residues such as lemongrass (Cymbopogon nardus L.) waste have strong potential to be reused as livestock feed, helping improve sustainability and reduce environmental waste. However, their high lignin and crude fiber contents limit digestibility, making pretreatment necessary. One effective approach is solid-state fermentation (SSF) using white-rot fungi to enhance nutritional quality. During SSF, pH and moisture content are key indicators of process performance, but conventional measurement methods are slow and inefficient for real-time monitoring. In this study, near-infrared spectroscopy (NIRS) combined with partial least squares regression (PLSR) was evaluated as a rapid and non-destructive method to predict pH and …

Physicochemical, Organoleptic, And Antioxidant Functional Characteristics Of Dangke Whey Protein Ice Cream Fortified With Butterfly Pea Flower Extract, Muh. Achyar Ardat, Raden Hilman Wirayudha, Ekajayanti Kining, Zakiah Wulandari, Irma Isnafia Arief

Jurnal Ilmu Ternak Universitas Padjadjaran

This study aims to develop a functional ice cream based on dangke whey pro‐ tein with the addition of butterfly pea flower extract. Four formulations were pre‐ pared by varying milk and whey proportions: P1 (100% milk), P2 (60% milk + 40% whey), P3 (40% milk + 60% whey), and P4 (100% whey), with 5% butterfly pea ex‐ tract added to each treatment. The results showed that higher whey substitution decreased pH and overrun values but prolonged the melting resistance of ice cream. Moisture content increased with whey proportion, whereas ash content remained relatively constant across treatments. Protein and fat …

Identification Of Beef Cattle Farms Population Dynamics In Ngombol District, Purworejo Regency, Hendarto Kurniawan, Tri Puji Rahayu, Danes Suhendra

Jurnal Ilmu Ternak Universitas Padjadjaran

The dynamics of the beef cattle population are crucial in the development. The lack of data on the population dynamics of beef cattle farming in Purworejo District has resulted in less effective population control. The purpose of this research is to examine and understand the factors that influence the dynamics of the beef cattle population in Ngombol District. This research was conducted through surveys and observations of 35 farmers recommended by policy stakeholders in five villages with the highest beef cattle populations in Ngombol District. The observations were recorded in a questionnaire containing statements that identified the dynamics of the …

Consumer Preferences And The Impact Of Halal Labeling On Beef Purchasing Decisions In Modern Market Segments, I Putu Gede Didik Widiarta, Amalina Nur Wahyuningtyas, Andi Nurmasytha, I Gede Arie Mahendra Putra

Jurnal Ilmu Ternak Universitas Padjadjaran

Global demand for halal-certified products is rapidly increasing, underscoring the importance of understanding consumer preferences and the impact of halal labelling on purchasing decisions. This study examines the relationship between halal labelling, consumer trust, and purchasing behaviour of beef in modern markets in East Kalimantan, Indonesia. A quantitative survey was conducted with 400 respondents from diverse demographic backgrounds. The results show that 75% of consumers prefer halal-certified beef, with 80% perceiving halal labels as indicators of superior product quality and safety. Logistic regression analysis revealed that consumers who trust halal labels are 2.5 times more likely to purchase halal-certified beef …

Stephen Baenziger, Unl Agronomy & Horticulture, Breeding New Wheat Varieties, Mark Griep, P. Stephen Baenziger

UNL ORCA Interview Series

Stephen Baenziger awarded the ORCA in 2011. He was born in 1951 in Toronto, Canada. When he was an infant, his family immigrated to the U.S., where he grew up in Des Plaines, Illinois. He earned a bachelor's in biological chemistry magna cum laude from Harvard University in Cambridge, Massachusetts. Next, he earned a master's and doctorate in plant breeding and genetics at Purdue University in West Lafayette, Indiana. Over the next decade, he worked for the USDA at Beltsville Agricultural Research Center in Maryland and then at the Monsanto Corporation in St. Louis, Missouri. In 1986, he joined the …

Mental Health Self-Perceptions And Resource Utilization In Undergraduate Students At Binghamton University, Nicole J. Dreznin, Sarah Marcus

Binghamton University Undergraduate Journal

Undergraduate students face increasing rates of mental health challenges, however discrepancies in mental health literacy and utilization of resources may exist across student populations. This study examined the perceptions of mental health in undergraduate students at Binghamton University and if they differed among STEM vs non-STEM, man vs. women, and first-generation vs. continuing generation undergraduate students. A 20-question survey, containing 5 demographic questions and 15 mental health related questions was distributed through Qualtrics to 9 undergraduate classes. The available response choices were based on the Likert scale. A total of 1266 students participated.  Chi square tests of independence were done …

Gendered Analysis Of Fish Feed Ingredients And Sourcing Practices In Western Kenya’S Aquaculture, Kristie Drucza, Sujata Ganguly, Rodrigue Yossa, Chrysantus Tanga

All Peer-Reviewed Publications

Introduction – Fish feed management plays a central role in aquaculture productivity, but it is rarely analysed through a gender lens. This study examines how women and men differ in their use and sourcing of fish feed ingredients in smallholder aquaculture systems in Western Kenya. Drawing on feminist economics, it explores how everyday roles, access to resources, and mobility shape feed practices. Methods – The analysis uses survey data from 213 fish farmers, including 112 women and 101 men, across six counties in Western Kenya. A binary logit model was used to assess factors associated with the use of selected …

Developmental Stability Of Task-Rest Neural Efficiency In Youth Using A Threat And Cognitive Control Task, Parmis Khosravi, Julia O. Linke, Anjali D. Poe, Chase Antonacci, Reut Naim, Elise M. Cardinale, Katharina Kircanski, Anderson M. Winkler, Nathan A. Fox, Daniel Samuel Pine, Simona P. Haller

School of Medicine Publications

Behaviors arise from coordinated neural activity across diverse spatial and temporal scales. Prior work has linked better task performance and cognitive functioning to patterns of global network connectivity requiring minimal reconfiguration when switching between task demands. This metric indexing similarity in functional connectivity across task and rest has been termed “neural efficiency.” Here we assess stability of neural efficiency over approximately 3 years in adolescence, specificity across two task-rest combinations and associations with anxiety. At approximately age 16 and/or 19, 95 participants completed a resting state scan alongside a cognitive control and/or threat task. Neural efficiency was quantified as partial …

Real-Time Image Denoising And Reconstruction Using Generative Adversarial Networks (Gans), Roa'a M. Al_Airaji, Haider Th. Salim Alrikabi, Rula Kamil, Svyd Iryna

Karbala International Journal of Modern Science

This paper presents a real-time image denoising and reconstruction system based on a compact Generative Adversarial Network (GAN) designed for embedded systems and edge computing. The proposed model employs a [ generator and a PatchGAN discriminator, trained using hybrid loss function that combines L1, perceptual, and adversarial terms to balance pixel and perceptual realism. Evaluations were conducted on multiple datasets, including DIV2K, BSD68, SIDD, DND, RENOIR, and PolyU at noise levels (σ = 15, 25, 50). Quantitatively, the proposed model achieves an average PSNR of 32.8 dB and an SSIM of 0.88, which is higher by more than 3 dB …

The Double Attraction Paradox, Rem Jaen D. Krafft

Publications and Research

The Double Attraction Paradox is a podcast series that teaches adolescents how to navigate attraction through body language, limerence, and mirroring while understanding the psychology behind emotional connection. It is a manuscript that combines personal experience, observations, and research, inspired by Rem Jaen D. Krafft's high school crush. Not only does it provide a guide for teenagers and young adults, but it also encourages readers to better understand attraction, communication, and emotional development. The final chapter examines how peer pressure, traditional high school cliques, fear of rejection, and fear of intimacy may influence societal norms, emotional contagion, and relationship formation …

Influence Of Peristalsis On The Hemodynamic Analysis Of Magnetohydrodynamic Jeffrey Fluid In A Two-Layered Narrow Channel, N. Lavanya, G. Ravi Kiran, M. Varun Kumar, K. Rajyalakshmi

Mansoura Engineering Journal

In this paper, an analytical study of MHD-influenced hemodynamic of Jeffrey fluid during peristaltic transport in a two layered narrow channel is presented, a phenomenon that has substantial ramifications for microcirculatory dynamics in the cardiovascular system. The model assumes a Jeffery fluid in the core area to encapsulate microstructural phenomena, including viscosity fluctuations, whereas the periphery area is treated as a Newtonian fluid. The governing equations for both regions are simplified and analytically solved under the long wavelength approximation. Using MATHEMATICA, a numerical investigation is carried out to examine the influence of various parameters, such as the magnetic parameters, amplitude, …

Utilization Of Egyptian Flax For Industrial Applications: Sustainable Composite Tubes From Egyptian Flax Cord, Rania El Deeb, Alaa Arafa Badr, Shaimaa Youssef El-Tarfawy, Ahmed H. Hassanin, Ashraf Elnahrawy, Abdelhamid R. Aboalasaad

Mansoura Engineering Journal

The growing demand for eco-friendly products has increased interest in natural fibers such as flax for composite materials, yet high costs limit industrial adoption. This research aims to utilize less expensive Egyptian flax secondary fibers and multifunctional characterization of locally produced flax cords to develop high-performance composite tubes via filament winding. An additional objective is to treat these fibers for technical applications, offering a sustainable alternative to synthetic materials.

Egyptian flax cords were processed using a filament winding technique to fabricate composite tubes. The study investigated the effects of varying the number of layers (e.g., 80/14 and 40/14/40 configurations), the …

Survey Increases Understanding Of United States Sweetpotato Producer Clean Seed Needs, Lorin Harvey, Mark Shankle, Rachael Carter, Kelsey Harvey

Journal of Extension

A needs assessment of sweetpotato producers across the United States was conducted as part of a strategic planning process to enhance the applicability of research and education. A national survey and a 2-day grant-planning workshop were also used to engage stakeholders to develop a USDA–NIFA Specialty Crop Research Initiative Proposal to improve and promote clean seed programs. Ninety-five U.S. sweetpotato producers completed the survey, representing more than 73,000 acres of production. Therefore, the survey respondents are estimated to account for nearly half of U.S. sweetpotato production, underscoring the importance and relevance of the results.

Strategic Leverage Points For Effective Watershed Governance: A Micmac Structural Analysis Approach, Ivan Taslim, Sambas Basuni, Moh. Yanuar Jarwadi Purwanto, I Putu Santikayasa

Journal of Environmental Science and Sustainable Development

Over the past two decades, watershed governance in Indonesia has been challenged by rapid land-use change, fragmented institutions, and limited integration of scientific evidence into policy. Previous studies have primarily evaluated watershed sustainability using hydrological or socio-economic indicators, whereas the structural relationships among governance, socio-economic, and biophysical factors remain insufficiently explored. To address this gap, this study applies the Matrix of Cross-Impact Multiplications Applied to Classification (MICMAC) method to examine direct and indirect relationships among watershed governance factors. A pentahelix stakeholder analysis involving government, academia, non-governmental organizations, media, and industry was conducted to evaluate 37 factors identified through a systematic …

Financial Analysis Tool (Ct-Ft) For Western North Carolina Christmas Tree Growers, Sam Blumenfeld, Solomon Ghezehei, Justin G.A. Whitehill, Elizabeth G. Nichols

Journal of Extension

Western North Carolina is a major national Christmas tree (CT) production region, yet the CT industry faces numerous challenges that threaten its financial sustainability. Little economic research has been done, and limited decision-making tools exist to assist producers, Extension agents, and associated industry stakeholders. We developed an Excel-based financial analysis tool (CT-FT) to assist small and midsize wholesale CT producers in operational planning and financial assessment. The publicly available financial tools will enable CT growers to better understand their finances and operations, interact with financial stakeholders, assess alternative management scenarios, and track yearly costs to improve operational financial sustainability.