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A Surface Defect Detection Model For Fused Images Of Fruits Based On Improved Resnet 18, Si Haiping, Zhao Wenrui, Zhao Yuyang, Li Tingting, Fernado Bacao, Li Yanling Jul 2026

A Surface Defect Detection Model For Fused Images Of Fruits Based On Improved Resnet 18, Si Haiping, Zhao Wenrui, Zhao Yuyang, Li Tingting, Fernado Bacao, Li Yanling

Food and Machinery

[Objective] To enhance the accuracy of detecting fruit surface defects caused by minor mechanical friction during transportation. [Methods] A surface defect detection model for fused images of fruits based on improved ResNet 18 is proposed. To address the challenge of multi-scale feature extraction, the model incorporates a MELA module designed to capture image details more comprehensively. Additionally, an energy function-based regularization loss function is introduced to collaboratively optimize the training process alongside the cross-entropy loss function. Furthermore, a transfer learning strategy is employed to mitigate overfitting. [Results] Experimental results demonstrated that the improved model exhibits exceptional performance in fruit surface …


Application Of Slow-Release Plant Essential Oil Preservative Combined With Electron Beam Irradiation In The Preservation Of Shanghai Sand Pears (Pyrus Pyrifolia Nakai ), Yue Ling, Lei Lei, Kong Qiulian, Zheng Qi, Yan Weiqiang Jul 2026

Application Of Slow-Release Plant Essential Oil Preservative Combined With Electron Beam Irradiation In The Preservation Of Shanghai Sand Pears (Pyrus Pyrifolia Nakai ), Yue Ling, Lei Lei, Kong Qiulian, Zheng Qi, Yan Weiqiang

Food and Machinery

[Objective] To investigate the regulatory effects of a composite preservation technology combining slow-release plant essential oil (SPEO) with electron beam irradiation on the storage quality and physiological metabolism of Shanghai sand pears (Pyrus pyrifolia Nakai). [Methods] The fruits of Shanghai sand pear variety 'Cuiguan' are used as test materials. The experiment is conducted with four groups: control, 0.5 kGy electron beam irradiation, SPEO, and 0.5 kGy electron beam irradiation + SPEO. During storage, quality parameters including fruit firmness, weight loss rate, total soluble solids (TSS) content, titratable acid content, and vitamin C (VC) content, as well as physiological metabolism indicators …


Effect Of Brewing Methods On Colloidal Particle Properties And Antioxidant Characteristics Of Coffee, Gao Guanzhen, Rao Pingfan, Han Cheng, Wang Huiqin, Shan Yunhui Jul 2026

Effect Of Brewing Methods On Colloidal Particle Properties And Antioxidant Characteristics Of Coffee, Gao Guanzhen, Rao Pingfan, Han Cheng, Wang Huiqin, Shan Yunhui

Food and Machinery

[Objective] To investigate the effects of three typical brewing methods - hand drip, French press, and Turkish coffee - on the chemical composition, colloidal structure, and antioxidant activity of coffee, and to elucidate the mechanism of colloidal particles in the delivery of bioactive compounds. [Methods] Three types of coffee samples are prepared using the respective brewing methods. Their physicochemical components are determined and colloidal properties are characterized. The true solution phase and colloidal phase are separated by ultrafiltration, and their in vitro chemical and intracellular antioxidant activities are comparatively evaluated. [Results] Turkish coffee exhibits the highest extraction yield, but thermal …


Dynamic Changes Of Major Non-Volatile Components During Gongfu Black Tea Processing, Deng Ming, Chen Liang, Liu An, Wei Dongning, Wu Wenliang, Wu Xiaofen, Qi Hui Jul 2026

Dynamic Changes Of Major Non-Volatile Components During Gongfu Black Tea Processing, Deng Ming, Chen Liang, Liu An, Wei Dongning, Wu Wenliang, Wu Xiaofen, Qi Hui

Food and Machinery

[Objective] To investigate the dynamic changes in the major non-volatile chemical components during the processing of Jianghua Kucha 21-3 Gongfu black tea. [Methods] Fresh one-bud-two-leaf autumn tea leaves of Jianghua Kucha 21-3 were used as raw materials. Samples at different processing stages were obtained by liquid nitrogen pre-freezing and freeze-drying. The mass fractions of water extract, tea polyphenols, catechins, theaflavins (TFs), thearubigins (TRs), theabrownins (TBs), caffeine, theanine, free amino acids, and soluble sugars were determined. Additionally, sensory evaluation was conducted on Gongfu black tea processed with different fermentation durations. [Results] During processing, the mass fraction of water extract in Jianghua …


Effects Of Extraction Methods On The Composition And Physicochemical Properties Of Flavonoids From Lycium Barbarum Leaves, Li Juanxia, Li Jianxin, Gao Jianying, Mai Wenting, Fan Yanli, Ma Jinchao, Meng Xuemei Jul 2026

Effects Of Extraction Methods On The Composition And Physicochemical Properties Of Flavonoids From Lycium Barbarum Leaves, Li Juanxia, Li Jianxin, Gao Jianying, Mai Wenting, Fan Yanli, Ma Jinchao, Meng Xuemei

Food and Machinery

[Objective] To investigate the effects of different extraction methods on the efficacy, chemical composition, and functional group characteristics of flavonoids in Lycium barbarum leaves. [Methods] This study comparatively analyzes the effects of three methods - ultrasound-assisted ethanol extraction (UAE), microwave-assisted ethanol extraction (MAE), and aqueous two-phase system (ATPS) - on the yield, composition, and in vitro antioxidant activity of flavonoids from L. barbarum leaves. [Results] UAE and MAE achieve the highest yield of flavonoids from dried L. barbarum leaves. The main components are rutin, quercetin, chlorogenic acid, and kaempferol. The antioxidant capacity of the flavonoid extract from dried L. barbarum …


Numerical Simulation Of Humidity Field In Baijiu Fermentation Rooms And Influencing Factors, Hao Qi, Shi Yan, Yang Zhengquan, Lin Chunsong, Xu Guangqi, Wen Enhan Jul 2026

Numerical Simulation Of Humidity Field In Baijiu Fermentation Rooms And Influencing Factors, Hao Qi, Shi Yan, Yang Zhengquan, Lin Chunsong, Xu Guangqi, Wen Enhan

Food and Machinery

[Objective] To investigate the effects of ventilation conditions and Daqu stacking methods in the fermentation room on the humidity levels at various points within the room. [Methods] A three-dimensional unsteady gas-solid coupling model of a small-scale fermentation room is established. Then, the humidity field variation patterns in the room are analyzed using the height of the humidifying air supply outlet (H), the interlayer spacing of fermentation racks (h), and the gap between fermentation piles (δ) as variables. Additionally, multi-objective optimization is performed based on response surface methodology (RSM) and the non-dominated sorting genetic algorithm II (NSGA-II). [Results] H, h, and …


Peeling Effect Of Three-Dimensional Turbulent Flexible Friction For Small Yellow Ginger, Sun Fang, Lu Kuirong, Jiang Shuiquan Jul 2026

Peeling Effect Of Three-Dimensional Turbulent Flexible Friction For Small Yellow Ginger, Sun Fang, Lu Kuirong, Jiang Shuiquan

Food and Machinery

[Objective] Aiming at the industrial bottleneck that the industrial peeling of small yellow ginger cannot balance high peel removal rate and low flesh damage rate due to its irregular shape, dense branches, thin and tender peel, a piece of peeling equipment based on three-dimensional turbulent flexible friction is developed. [Methods] Small yellow ginger is taken as the test material. With peel removal rate and flesh retention rate as evaluation indicators, single-factor and L9(34) orthogonal experiments are carried out to optimize three key parameters: processing time, material-water ratio, and stirring speed. Origin is used for data statistics and analysis. [Results] The …


Design And Application Of Low-Temperature Heat Pump Belt Drying Technology In Soy Sauce Residue Drying Process, Liu Shumo, Wang Liangliang, Qi Yan, Luo Zhiqiang, Cao Lei Jul 2026

Design And Application Of Low-Temperature Heat Pump Belt Drying Technology In Soy Sauce Residue Drying Process, Liu Shumo, Wang Liangliang, Qi Yan, Luo Zhiqiang, Cao Lei

Food and Machinery

[Objective] To address key issues in conventional soy sauce residue drying processes, including high energy consumption, severe equipment corrosion, and the susceptibility of heat-sensitive nutrients to degradation, a novel integrated drying system was designed and developed to achieve high efficiency, energy savings, and reliable product quality. [Methods] The system integrates key technologies such as spiral air-duct drying and two-stage dust removal. Based on the reverse Carnot cycle principle of a heat pump, a low-temperature drying environment of 40~75 ℃ was established, with the aim of reducing energy consumption while maximizing the retention of the material’s original quality. [Results] The system …


Research Progress On Plant-Derived Metal Ion Chelating Peptides, Pei Hanzhe, Zhao Hongfei, Zhou Jiahua, Zhang Bolin, Chen Yonghao Jul 2026

Research Progress On Plant-Derived Metal Ion Chelating Peptides, Pei Hanzhe, Zhao Hongfei, Zhou Jiahua, Zhang Bolin, Chen Yonghao

Food and Machinery

Mineral element deficiency can cause many health problems. Traditional metal element supplements have many shortcomings. Food-derived metal element supplements have gradually become a research hotspot. Plant-derived polypeptides have significant advantages in terms of cost and raw material sources. Chelating peptides formed by chelating metal ions with plant-derived polypeptides have the physiological activity of peptides and the functional characteristics of metal elements, which makes them relatively ideal nutritional supplements, showing broad development prospects. This paper collects relevant research reports at home and abroad, and sorts out the preparation process, chelation mechanism and characteristics, and biological activity of plant-derived metal ion chelating …


Research Advances In Rice Bran Oil Bioactive Components And Antioxidant Technologies, Tu Yue, Guo Xiongchang, Zhang Wenhan, Cai Lichuang, Liu Jianping Jul 2026

Research Advances In Rice Bran Oil Bioactive Components And Antioxidant Technologies, Tu Yue, Guo Xiongchang, Zhang Wenhan, Cai Lichuang, Liu Jianping

Food and Machinery

Rice bran oil is a unique natural edible oil with healthy benefits and a reasonable fatty acid composition. Containing natural antioxidant components including phytosterols, oryzanol, tocotrienols, and squalene, rice bran oil is characterized by high nutritional value, diverse physiological functions, and excellent frying performance, thus demonstrating broad application potential. This study reviews the research advances in the bioactive components, physiological functions, factors influencing oxidative stability, and antioxidant technologies of rice bran oil, while providing prospects for future development.


Research Progress On Effect Of Salt On Pickling Vegetable Quality, Qi Kai, Li Ziyan, Cheng Wenbo, Fan Mingcong, Zuo Daoxi, Li Yan, Wang Li, Zhang Wenbin Jul 2026

Research Progress On Effect Of Salt On Pickling Vegetable Quality, Qi Kai, Li Ziyan, Cheng Wenbo, Fan Mingcong, Zuo Daoxi, Li Yan, Wang Li, Zhang Wenbin

Food and Machinery

Vegetable pickling is a time-honored food preservation and processing method, in which salt (primarily sodium chloride) plays an irreplaceable and core role. This paper systematically reviews the multidimensional effects of curing salt on vegetable quality. It comprehensively covers preservation mechanisms, textural transformations, the formation and conversion of flavor compounds, color stability, and nutritional value changes. Specifically, this article analyzes the decisive role of salt concentration gradients in final product characteristics. Furthermore, it examines the challenges posed by the low salinity, including microbial safety risks, textural deterioration, and flavor imbalances, while proposing corresponding strategies.


Research Progress In The Extraction And Purification Processes And Biological Activities Of Flavonoids From Cuscutae Semen, Li Renxin, Xiong Ying, Song Hui Jul 2026

Research Progress In The Extraction And Purification Processes And Biological Activities Of Flavonoids From Cuscutae Semen, Li Renxin, Xiong Ying, Song Hui

Food and Machinery

Cuscutae Semen is a Chinese herbal medicine and a raw material for health foods in China, with flavonoids being a group of its main functional components. This article provides a systematic review of the extraction and purification techniques - reflux, ultrasonic, Soxhlet, microwave-assisted, flash, enzymatic hydrolysis, and supercritical CO2 extraction methods - of flavonoids from Cuscutae Semen. Furthermore, it elaborates on the biological activities such as reproductive protection, anti-tumor effect, anti-oxidative stress effect, liver and kidney protection, and immune regulation of flavonoids from Cuscutae Semen, as well as their related mechanisms. Moreover, this paper makes an outlook on the development …


Biomechanical And Talar Cartilage Responses To Running In Individuals With Chronic Ankle Instability, Minsub Oh Jul 2026

Biomechanical And Talar Cartilage Responses To Running In Individuals With Chronic Ankle Instability, Minsub Oh

Theses and Dissertations

Context: Chronic ankle instability (CAI) has shown altered movement patterns and joint loading, which increase the risk of posttraumatic ankle osteoarthritis. Abnormal vertical ground reaction force (vGRF) during running may contribute to talar cartilage degeneration; however, the acute biomechanical and cartilage responses to running in individuals with CAI remain unclear. Purpose: The purpose of this study was to compare running biomechanics and changes in talar cartilage thickness and T2 relaxation times before and after running between individuals with CAI and healthy controls. Methods: Twenty individuals with CAI and 20 healthy controls completed running biomechanics and magnetic resonance imaging (MRI) sessions. …


Irrigation Water Conservation And Accelerated Composting: An Exploration Of Environmentally Conscious Practices For Ornamental Horticulture, William James Carson Dunford Jul 2026

Irrigation Water Conservation And Accelerated Composting: An Exploration Of Environmentally Conscious Practices For Ornamental Horticulture, William James Carson Dunford

LSU Master's Theses

Best management practices for ornamental horticulture include proper management of irrigation water resources and substrate components. The first study investigated the effects of wind speed, wind direction, water pressure, and spray stake height on irrigation efficiency in nursery containers. Results indicated that lower spray stake height positions and lower wind speeds significantly improved the irrigation water volume captured within nursery containers by as much as 18% to 39%. Orienting spray stakes against prevailing winds further enhanced water retention, particularly at 0 and 1 inch heights. In contrast, higher stake elevations led to increased irrigation water loss by as much as …


Using A Cell Flux Model To Investigate Phytoplankton Growth And Macromolecular Allocation Under Iron Limitation, Margaret Bernish, Meng Gao, Jongsun Kim, Benoit Pasquier Jul 2026

Using A Cell Flux Model To Investigate Phytoplankton Growth And Macromolecular Allocation Under Iron Limitation, Margaret Bernish, Meng Gao, Jongsun Kim, Benoit Pasquier

School of Earth, Environmental, & Marine Sciences Faculty Publications

Global biogeochemical models are powerful tools used to interpret observations and empirical data, create hypotheses, and make predictions. Many of these models, however, represent marine microbes as static stoichiometric reactions that convert nutrients into biomass. To better constrain the biological processes that control nutrient cycling in the global ocean, we extend the Cell Flux Model of Phytoplankton to explore the impact of dissolved iron concentration on the allocation of macromolecules and elemental ratios within phytoplankton cells. This model is supported by data obtained from a range of incubation experiments conducted with phytoplankton of varying species and size categories. Model output …


Embedding Creative Communities In Urban Tourism Planning: Toward A Smart Culture Ecosystem For Sustainable City Development In Surakarta, Indonesia, Istijabatul Aliyah, Rara Sugiarti, Ratri Werdiningtyas, Arzaq Taukida, Fausta Ezra Firzatullah, Reyza Amrulloh Jul 2026

Embedding Creative Communities In Urban Tourism Planning: Toward A Smart Culture Ecosystem For Sustainable City Development In Surakarta, Indonesia, Istijabatul Aliyah, Rara Sugiarti, Ratri Werdiningtyas, Arzaq Taukida, Fausta Ezra Firzatullah, Reyza Amrulloh

Journal of Environmental Science and Sustainable Development

Creative communities are increasingly integrated into urban tourism, yet their environmental performance remains underexplored. To address this gap, this study introduces the Creative Cluster Environmental Performance Index (CCEPI), a novel composite socio-ecological assessment tool for integrating environmental performance into creative tourism planning and governance. This study employed a qualitative socio-spatial design Geographic Information Systems (GIS) analysis and policy review (2021 to 2023). The framework is applied to evaluate environmental performance across five creative clusters in Surakarta, Indonesia: Laweyan, Kauman, Pasar Gede, Sudiroprajan, and Alun-Alun Kidul. The CCEPI integrates ten indicators across five creative clusters in Surakarta, Indonesia: Pasar Gede, Alun-Alun …


Plant Diversity Modifies Multi-Trophic Interactions In Croplands, Grasslands And Forests, Nian Feng Wan, Muyao Li, Siyuan Shen, Jun Xiang Zhou, Yu Tong Zhu, Ben A. Woodcock, Yue Qing Hu, Shinichi Nakagawa, David Tilman, Andy Hector, Michel Loreau, Peter B. Reich, Matteo Dainese, Forest Isbell, Bernhard Schmid, Kris A.G. Wyckhuys, Geoff M. Gurr, Linsheng Wan, Nico Eisenhauer, Yann Hautier, Anu Eskelinen, Richard D. Bardgett, Paul Kardol, Lauchlan H. Fraser, Qi Su, Shiyun Qiu, Yavanna Aartsma, Ramon Albajes, Matthias Albrecht Jul 2026

Plant Diversity Modifies Multi-Trophic Interactions In Croplands, Grasslands And Forests, Nian Feng Wan, Muyao Li, Siyuan Shen, Jun Xiang Zhou, Yu Tong Zhu, Ben A. Woodcock, Yue Qing Hu, Shinichi Nakagawa, David Tilman, Andy Hector, Michel Loreau, Peter B. Reich, Matteo Dainese, Forest Isbell, Bernhard Schmid, Kris A.G. Wyckhuys, Geoff M. Gurr, Linsheng Wan, Nico Eisenhauer, Yann Hautier, Anu Eskelinen, Richard D. Bardgett, Paul Kardol, Lauchlan H. Fraser, Qi Su, Shiyun Qiu, Yavanna Aartsma, Ramon Albajes, Matthias Albrecht

All Peer-Reviewed Publications

Multitrophic interactions can strongly influence the structure and functioning of ecosystems, but how plant diversity influences the direction and predictability of multitrophic interactions across agricultural and natural ecosystems remains unclear. Using 149 field studies across five continents, we found that, on average, increasing plant diversity tended to exert differential top-down and bottom-up effects in croplands versus grasslands and forests. Organic and nonorganic croplands exhibited 846 and 148% higher invertebrate natural enemy-to-herbivore abundance ratios under increased plant diversity, consistent with top-down control patterns where predator gains cause herbivore declines, enhancing crop outcomes. In grasslands and forests, increasing plant diversity was associated …


Pharmacological Potential Of Pomelo (Citrus Maxima) Peel: A Bibliometric Review Of Global Research Trends And Future Directions, Indah Zunita Sari, Alma Nur Azizah, Fitriana Nur Hanifah, David Fernando, Agung Endro Nugroho, Abdul Rohman Jul 2026

Pharmacological Potential Of Pomelo (Citrus Maxima) Peel: A Bibliometric Review Of Global Research Trends And Future Directions, Indah Zunita Sari, Alma Nur Azizah, Fitriana Nur Hanifah, David Fernando, Agung Endro Nugroho, Abdul Rohman

Journal of Food and Drug Analysis

Pomelo (Citrus maxima) is a widely cultivated tropical fruit with global production reaching approximately 8.55 million tons in 2023. This large-scale production generates a substantial amount of peel waste despite the fact that pomelo peel contains secondary metabolites with promising pharmacological potential. This study aimed to evaluate global research trends related to the pharmacological potential of pomelo peel using a bibliometric and review-based approach, as well as to identify future research directions. Data were collected from the Scopus database and filtered for English-language scientific articles, reviews, and conference proceedings. The analysis was performed using the Biblioshiny and VOSviewer …


Plant By-Products As A Valuble Source Of Natural Antiglycemic Compounds: Economic Aspects And Alternative Raw Material Sources, Tatjana Đorđević, Jelena Vujetić, Isidora Dickov, Diandra Pintać Šarac Jul 2026

Plant By-Products As A Valuble Source Of Natural Antiglycemic Compounds: Economic Aspects And Alternative Raw Material Sources, Tatjana Đorđević, Jelena Vujetić, Isidora Dickov, Diandra Pintać Šarac

Journal of Food and Drug Analysis

Plant by-products, often considered as waste in various agricultural and food processing industries, have emerged as a valuable source of natural antidiabetic or antihyperglycemic compounds. These compounds, derived from plant materials that would otherwise be discarded, have the potential to mitigate the global burden of diabetes and offer sustainable solutions for glycemic control. Prominent groups of natural antidiabetic compounds found in plant by-products are polyphenols, as well as bioactive proteins and peptides. In addition, agro-industrial residues such as wheat bran, oat husks, and fruit peels are excellent sources of carbohydrates that can be incorporated into functional foods to help manage …


Emerging Antifungal Strategies Against Candida Albicans Using Metal–Organic Frameworks And Novel Therapeutics: Opportunities And Challenges, Amanpreet Singh, Sandeep Kumar, Sehrabpreet Singh, Jeewanjot Singh Jul 2026

Emerging Antifungal Strategies Against Candida Albicans Using Metal–Organic Frameworks And Novel Therapeutics: Opportunities And Challenges, Amanpreet Singh, Sandeep Kumar, Sehrabpreet Singh, Jeewanjot Singh

Journal of Food and Drug Analysis

Candida albicans is an opportunistic fungal pathogen responsible for infections ranging from superficial mucosal disease to life-threatening systemic candidiasis, particularly in immunocompromised hosts. Its pathogenicity is enhanced by morphological plasticity, biofilm formation, and immune evasion, contributing to antifungal resistance. Limitations of existing antifungals have driven interest in emerging therapeutics. This review highlights strategies including metal–organic frameworks (MOFs), host-directed therapies (HDTs), CRISPR-Cas9 gene editing, and phytochemicals. MOFs offer high drug-loading capacity, controlled release, and enhanced penetration into biofilms, showing promise against drug-resistant strains. Selected phytochemicals demonstrate inhibitory effects on virulence traits such as hyphal formation and enzyme secretion. CRISPR-Cas9 …


An Optical Fiber Caffeine Sensor Using A Molecularly Imprinted Polymethacrylic Acid Membrane Coated On Optical Fiber Surface As A Transducer, Josiah W. Miller, Jason D. Mccaslin, Shiquan Tao Jul 2026

An Optical Fiber Caffeine Sensor Using A Molecularly Imprinted Polymethacrylic Acid Membrane Coated On Optical Fiber Surface As A Transducer, Josiah W. Miller, Jason D. Mccaslin, Shiquan Tao

Journal of Food and Drug Analysis

Caffeine is a neurotransmitter, important to human health. This compound exists in many food products, has been added to soft drinks, pharmaceutical drugs. For many applications, a field deployable technique for quick detecting caffeine is attractive. In this paper, we report a selective optical fiber caffeine sensor using a molecularly imprinted polymer (MIP) membrane as a transducer. The membrane extracts/concentrate caffeine from sample solutions significantly improved sensor’s sensitivity with a 95 times sensitivity improvement. The sensor achieved a detection limit of 0.20 µg/mL. This sensor was used to directly analyze caffeine in soft drink products without interference from sample matrix.


Corrigendum To " Urban Transportation Strategy As Urban Sustainable Indicator Frameworks Study Of Masdar City, Abu Dhabi", Rania Badawy Shokry Jul 2026

Corrigendum To " Urban Transportation Strategy As Urban Sustainable Indicator Frameworks Study Of Masdar City, Abu Dhabi", Rania Badawy Shokry

Mansoura Engineering Journal

No abstract is required for this article.


Electroceuticals In Neuromodulation: Mechanisms, Clinical Applications, And Future Directions, Albashir Tahir, Nura Bello Jul 2026

Electroceuticals In Neuromodulation: Mechanisms, Clinical Applications, And Future Directions, Albashir Tahir, Nura Bello

AUIQ Complementary Biological System

Electroceuticals have emerged as an innovative therapeutic approach that employs targeted electrical stimulation to modulate neural circuits and restore physiological balance. Unlike conventional pharmacological treatments, which act through systemic biochemical pathways, electroceuticals enable precise spatial and temporal control of neural activity. The rapid proliferation of electroceutical devices across clinical and investigational settings, combined with accelerating advances in artificial intelligence, closed-loop engineering, and bioelectronic interface design, has generated an urgent need for rigorous, critically appraised synthesis to guide evidence-based clinical adoption and inform future research priorities. This review addresses the rapidly expanding field of bioelectronic medicine by providing a critical synthesis …


Cytotoxicity Of Bioactive Peptides From Cowpea (Vigna Unguiculata L. Walp) Against Breast Cancer Cells (Mcf-7), Dian R. Ningsih, Zusfahair Zusfahair, Ely Setiawan, Purwati Purwati, Kasta Gurning, Fitri A. Puspita Sari, Elya Widiawati Jul 2026

Cytotoxicity Of Bioactive Peptides From Cowpea (Vigna Unguiculata L. Walp) Against Breast Cancer Cells (Mcf-7), Dian R. Ningsih, Zusfahair Zusfahair, Ely Setiawan, Purwati Purwati, Kasta Gurning, Fitri A. Puspita Sari, Elya Widiawati

Karbala International Journal of Modern Science

Cancer is characterized by dysregulated metabolic signaling pathways, leading to uncontrolled cellular proliferation. Current cancer treatments, which involve surgery, radiotherapy, and chemotherapy, still cause adverse systemic toxicities. Accordingly, one possible effort that can be undertaken is to explore safe anticancer substances from protein sources such as peptides. Bioactive peptides can be isolated by hydrolyzing cowpea (Vigna unguiculata L. Walp) protein with trypsin. The objectives of this study were to isolate and fractionate bioactive peptides from cowpea, to determine the anticancer activity of peptide fractions, to identify active peptide fractions as anticancer agents using Liquid Chromatography High Resolution Mass Spectrometry …


In Vivo Expression Profiling Of Listeria Monocytogenes Internalins (Inlf, Inlp, Inlj) And Their Corresponding Host Receptors (Vim, Afdn, Muc2) Using A Rabbit Ligated Intestinal Loop Model, Nawar Al-Janabi, Nadhim Mushtaq Hashim Al-Bderee, Zahraa M. Madania, Mohanad Jawad Kadhim Jul 2026

In Vivo Expression Profiling Of Listeria Monocytogenes Internalins (Inlf, Inlp, Inlj) And Their Corresponding Host Receptors (Vim, Afdn, Muc2) Using A Rabbit Ligated Intestinal Loop Model, Nawar Al-Janabi, Nadhim Mushtaq Hashim Al-Bderee, Zahraa M. Madania, Mohanad Jawad Kadhim

Karbala International Journal of Modern Science

Listeria monocytogenes is a Gram-positive pathogen that causes severe infections, particularly in immunocompromised individuals. Internalin genes are important virulence factors that facilitate the bacterium's invasion of host cells. This research aimed to quantify in vivo expression of selected internalin genes (inlF, inlP, and inlJ) and their corresponding host receptors (VIM, AFDN, and MUC2) during L. monocytogenes infection. To achieve this aim, a rabbit ligated intestinal loop model was constructed comprising two intestinal loops. The first loop was injected with 1 mL of L. monocytogenes (1 × 10⁷ CFU/mL), while the second loop was injected with 1 mL of PBS as …


Exogenous Ribosome Incorporation Induces Lineage Transdifferentiation In Intestinal And Liver Cancer Cells, Haoxuan Gu, Nadia Wahyuningsih, Keisuke Yamashita, Shota Inoue, Fuchao Tan, Mani Sharaki, Muhaimin Rifa’I, Kunimasa Ohta Jul 2026

Exogenous Ribosome Incorporation Induces Lineage Transdifferentiation In Intestinal And Liver Cancer Cells, Haoxuan Gu, Nadia Wahyuningsih, Keisuke Yamashita, Shota Inoue, Fuchao Tan, Mani Sharaki, Muhaimin Rifa’I, Kunimasa Ohta

Karbala International Journal of Modern Science

It has previously been shown that exogenous bacterial ribosomes added to somatic cells and various cancer cell lines generate ribosome-induced cell clusters (RICs) capable of transdifferentiating into multiple cellular lineages. However, the scope of ribosome-induced transdifferentiation in cancer cells remains poorly understood. This study aimed to analyze the effects of exogenous ribosome incorporation on human cancer cell lines, specifically the intestinal epithelial cell line Caco-2 and the hepatocellular carcinoma cell line HepG2. Caco-2 and HepG2 cells were cultured with purified bacterial ribosomes in human ES/iPS cell medium after trypsinization, resulting in the formation of ribosome-induced Caco-2 (RICs-Ca) and HepG2 (RICs-He) …


Selenoprotein P And Selenium As Potential Diagnostic Biomarkers For Breast Cancer Patients, Farah A. Rashid, Rawaa A. Ali, Hanaa A. Ali Jul 2026

Selenoprotein P And Selenium As Potential Diagnostic Biomarkers For Breast Cancer Patients, Farah A. Rashid, Rawaa A. Ali, Hanaa A. Ali

Karbala International Journal of Modern Science

Breast cancer incidence increases in last decade. Oxidative stress increases during cancer development causes consuming of antioxidants. Selenium and its transporting protein, selenoprotein P have an important role in redox homeostasis. This study aims to investigate whether or not selenium and selenoprotein P could be diagnostic biomarkers for breast cancer patients. This study was included 30 individuals in control group who is age- and BMI-matched with 60 breast cancer patients. Selenium was measured by colorimetric assay kit and selenoprotein P was determined by Sandwich ELISA kits. The results indicate significant decrease (p < 0.0001) of serum selenium and selenoprotein P in breast cancer patients compared to control. A positive significant correlation (r = 0.6214, p < 0.0001) was found between selenium and selenoprotein P in breast cancer patients. Selenium has an excellent diagnostic accuracy with area under curve 0.9831, sensitivity 95% and specificity 100% at cut-off less than 3.54 mmol/L. Furthermore, selenoprotein P has also an excellent area under curve 0.9958 with sensitivity 96.77% and specificity 100% at cut-off less than 4.15 ng/ml. These exploratory findings appear that selenium and selenoprotein P could be potential diagnostic biomarkers for breast cancer patients. Further investigations in large-multicenter populations are needed to confirm results.


Tapping Into The Ocean’S Hidden Energy: Feasibility Of A 5 Mw Otec Installation In North Bali, Widodo Setiyo Pranowo, Yani Permanawati, Gisela Malya Asoka Anindita, Agung Kurniawan, Albertus Sulaiman, Johar Setiyadi, Safri Burhanuddin, Ivonne Milichristi Radjawane, Hansan Park, Endro Sigit Kurniawan Jul 2026

Tapping Into The Ocean’S Hidden Energy: Feasibility Of A 5 Mw Otec Installation In North Bali, Widodo Setiyo Pranowo, Yani Permanawati, Gisela Malya Asoka Anindita, Agung Kurniawan, Albertus Sulaiman, Johar Setiyadi, Safri Burhanuddin, Ivonne Milichristi Radjawane, Hansan Park, Endro Sigit Kurniawan

Karbala International Journal of Modern Science

Indonesia is an archipelagic country surrounded by water and faces energy challenges due to the low use of renewable energy. Among the potential renewable options, marine energy is a particularly suitable resource given the country’s geographical nature. Based on this discussion, seawater temperature can be used as an alternative ocean thermal en-ergy known as ocean thermal energy conversion (OTEC) by using the difference in sea surface and deep-sea water temperatures. Therefore, this study aimed to examine OTEC installations in North Bali waters using closed-cycle OTEC calculations for a 5 MW system. Following this objective, we examined the water conditions by …


Lameness In Dairy Cattle: A Practical Overview, Drew Swartz, Kalen Taylor, Jacob Hadfield, Justin Wyatt Clawson Jul 2026

Lameness In Dairy Cattle: A Practical Overview, Drew Swartz, Kalen Taylor, Jacob Hadfield, Justin Wyatt Clawson

All Current Publications

This fact sheet provides an overview of lameness in dairy cattle, including what it is, why it matters, and how to recognize and manage it. Information is geared toward producers, consultants, and educators.


Drifting Neurons, Stable Geometry: Population Representations Of Instrumental Behavior In The Dorsomedial Striatum, Arati Sharma Jul 2026

Drifting Neurons, Stable Geometry: Population Representations Of Instrumental Behavior In The Dorsomedial Striatum, Arati Sharma

Dartmouth College Ph.D Dissertations

The brain reliably supports learned behaviors over long periods of time despite continual biological changes that alter the activity of individual neurons, and the connections between them. For learned behaviors to persist, the information stored in neural populations must remain accessible even when the activity of individual neurons changes. Understanding how the brain achieves this is a fundamental challenge in neuroscience. The dorsomedial striatum (DMS) is critical for instrumental behavior, encoding information about actions, outcomes, and their relationships. Although extensive work has characterized the role of the DMS during learning and performance, less is known about how task-related information is …