Digital Commons Network^™

Milk-Fed Astronauts In A Microbial Galaxy, Charlie Lanning

Osmosis Magazine

No abstract provided.

Where’S Perry? The Strange Biology Of The Platypus, Carolina Mosquera

Osmosis Magazine

No abstract provided.

Is Artifical Intelligence "Truly" Intelligent?, Camila Nicole Valdman

Osmosis Magazine

No abstract provided.

What's In Tuburculosis, That Which We Call 'Chic?', Ainsley Coleman

Osmosis Magazine

No abstract provided.

Letter From The Editor, Eliz Ustun

Osmosis Magazine

No abstract provided.

Rna Interference Targeting Autocrine Motility Factor Receptor In Unfolded Protein Response In Acyrthosiphon Pisum, Micah A. Von Stroh, James Balthazor

SACAD: Scholarly Activities

Acyrthosiphon pisum, more commonly known as pea aphids, are a pest to many species of Fabaceae (legumes) mainly due to the species being prone to carrying Fabaceae diseases. Protection against A. pisum currently includes insecticides and natural predators, both of which bring potential negative effects to other organisms in the surrounding area. In this study, the use of RNA interference (RNAi) provides an alternative and species-specific elimination of A. pisum. The targeted proteins in this study, Autocrine Motility Factor Receptor, plays a role in removing misfolded proteins from the cells of A. Pisum and is encoded by the AMFR gene. …

Atp Architect - Development Of A Metabolism Boardgame, Selene J. Welch, Micah Burk, Brooklyn Gilchrist, Emma Haase, Timothy T. Jones

SACAD: Scholarly Activities

Traditional metabolism instruction often leaves students struggling with pathway interconnectedness and metabolite flux. To foster systems thinking, we are developing an educational board game where students manipulate tokens to navigate physiological constraints and achieve target energy goals. Grounded in Design-Based Research (DBR), the game undergoes iterative refinement based on player feedback. The design utilizes constructivism by allowing students to "fail safely" and revise strategies in real-time, while leveraging embodied cognition to externalize abstract flux into the physical trading of resource tokens.

Structural Transformation Of A Hydrogel-Forming Cell Division Protein Zapb Of Multidrug Resistant Klebsiella Pneumoniae With Small Molecules, Ayesha Khan, M. Iqbal Choudhary, Sumaira Javaid, Humaira Zafar, Innokentiy Maslennikov, Atia-Tul Wahab

Pharmacy Faculty Articles and Research

Septal ring assembly protein ZapB (EMR18431.1) is involved in Z-ring formation, and nucleoid segregation during the bacterial cell division . It promotes cell division in the initial stages of the cell cycle through direct interaction with FtsZ, thus stimulating Z-ring assembly. The ZapB inhibition can make bacterial cell susceptible to primary antibiotics, and therefore considered as an important approach for adjuvent therapy against MDR bacterial infections. Hence in the current study, ZapB protein of multidrug resistant Klebsiella pneumoniae was cloned, and expressed in E. coli system. To understand its role, and to assess the mechanism of ZapB activation, the characteristic …

Redox Reprogramming In Neurogenesis: Candidate Developmental Switches And Targets Of Oxidative Toxicity In The Redox Proteome, Ryan Jacob Summerhays

Theses and Dissertations

Neurogenic differentiation requires coordinated redox regulation, yet how reversible cysteine oxidation is remodeled at proteome scale during this process remains poorly defined. Here, we asked whether differentiation is associated with selective, site-specific changes in reversible cysteine oxidation and whether oxidative stress reveals developmentally conditioned vulnerabilities within this redox landscape. To address this, we applied a discovery-oriented, proteome-scale redox profiling strategy that quantifies condition-dependent changes in reversible cysteine oxidation using CysPAT labeling, phosphopeptide enrichment, and multiplexed TMT mass spectrometry. Neurogenic differentiation was characterized by reproducible, bidirectional, and highly site-specific remodeling of reversible cysteine oxidation at discrete regulatory nodes, as well as …

Emergence, Differentiation, And Modeling Of Hematopoietic Stem Cells In Developing Embryos, Lucy Shive

Caroliniana Undergraduate Research Journal

In the field of developmental biology, the understanding of embryogenesis is driven by ever-advancing techniques of studying embryos’ structures and behaviors. Yolk sacs are critical to an embryo’s survival and its function in producing a mature organism from a simple zygote. A hallmark of embryonic yolk sacs is their production of primitive hematopoietic stem cells (HSCs). Recent research has explored the mechanisms by which these HSCs develop and migrate, as well as the mechanisms by which they differentiate into various cell types. This more thorough understanding of HSCs is the basis for the development of embryo models, peri-gastruloids, from stem …

Assessing Walleye Recruitment Via Otc Marks And Temporal Sampling Changes In Smallmouth Bass Population Structure In Lake Mcconaughy, Nebraska, Robert D. Allison Iv

Biology Theses, Dissertations, and Student Creative Activity

Lake McConaughy is a socially and economically important reservoir managed to provide diverse, high-quality angling opportunities. Walleye are the most frequently targeted species, although Smallmouth Bass have increased in popularity in recent years due to improvements in abundance and size structure. Walleye have been stocked annually since 1989 to support the population and have been the focus of extensive research. In contrast, Smallmouth Bass have been present for over 80 years and are self-sustaining; however, their population has not been formally evaluated since introduction.

The first objective of this study was to develop an oxytetracycline (OTC) mark retention correction factor …

Applications Of Machine Learning In Enhancing Evaporation Estimation For Small Reservoirs: A Case Study In Semi-Arid South Texas, Syed Muhammad F Abdullah, Chu-Lin Cheng, Jude A. Benavides, Jungseok Ho, Rafael M. Almeida

School of Earth, Environmental, & Marine Sciences Faculty Publications

Small reservoirs in semi-arid regions experience substantial evaporative losses but are rarely monitored at daily scales. A multi-reservoir machine learning (ML) framework was developed to estimate daily open-water evaporation. Empirical models (Penman, Penman-Monteith, Priestley-Taylor, Bowen Ratio Energy Budget) andabenchmark combination method (Daily Lake Evaporation Model-DLEM) were compared against ML models. Predictors combined gridded meteorology (gridMET) with reservoir attributes (surface area, average depth, maximum depth, and fetch). ML models (Random Forest-RF, Decision Tree-DT, K-Nearest Neighbor-KNN, and Support Vector Regression-SVR) were trained on four reservoirs using data from 2018 to 2025. Results from ML models were further validated using both DLEM and …

Singing Not To Sing: The Interplay Of The Environment And Behavior On The Reproductive Success Of Forest Breeding Migratory Birds, Miranda Bliss Zammarelli

Dartmouth College Ph.D Dissertations

Habitat selection is a key behavior that has consequences for fitness, which can shift with environmental variation. The environment can affect reproductive success indirectly by shaping behavior or via direct impacts. Many forest breeding migratory birds choose a habitat by establishing territories. To understand the interplay of environment and behavior on the reproductive success of forest breeding migratory birds, I leveraged long-term data and newly collected species-specific data from Hubbard Brook Experimental Forest, New Hampshire, USA. I analyzed over 50 years of territory maps from seven species occupying a 10-ha plot to understand how birds distribute themselves in a habitat. …

Study The Effect Of Climate Change On Barley Crop (Hordeum Vulgare L.) And Improving Its Productivity Through Municipal Treated Wastewater Utilization, Wasef A. Alzayadneh

Thesis/ Dissertation Defenses

Climate change presents a complex risk to crop productivity, with elevated temperatures, rising CO2 and UV-B enhancement profoundly impacting growth. Although the effects of individual stressors are well-documented, limited information is available regarding the combined effects of variables such as elevated CO₂ (eCO2), UV-B radiation, and elevated temperature (eT). This knowledge gap is especially critical for major cereal crops such as barley (Hordeum vulgare L.), which ranks fourth in global production and serves as a valuable source of forage for livestock. However, traditional forage production is unsustainable in arid regions, where water shortage and extreme weather conditions are present, as …

Studying The Role Of Combitional Flavonoids Against Toxicity Of Chemothrapeutic Drugs In Human Fibroblast Cells, Hussain Al Zouabi

Thesis/ Dissertation Defenses

Chemotherapy remains the primary treatment strategy for cancers; however, its clinical efficacy is often limited by severe toxic effects resulting in normal cells. The study investigated the protective potential of the flavonoids epigallocatechin-3-O-gallate (EGCG) and quercetin, used in combination, against chemotherapy-induced toxicity in human fibroblast F-180 cells. Cells were exposed to three commonly used chemotherapeutic agents, doxorubicin, cisplatin, and etoposide, in the presence or absence of EGCG and quercetin at concentrations of 25 and 50 μM. cells viability was assessed using the MTT assay, while oxidative stress and antioxidant capacity were evaluated by intracellular reactive oxygen species (ROS) and total …

Forest Characteristics And Avian Community Differences Among Cerulean Warblers (Setophaga Cerulea) Use Types, Dustin Kohler

ATU Scholars Symposium

Avian species are often used to measure the health of an ecosystem, in part because the specific forest structure can significantly impact the avian community. A heterogeneous landscape can support a more diverse avian community and benefit specialist species like the Cerulean Warbler (Setophaga cerulea), a rapidly declining, neotropical migrant that can be found in large deciduous forests. The Ozark Mountains of northwestern Arkansas represent a small core area for the species, but at all sites in the upland Ozarks where Cerulean Warbler research has been conducted, there are fewer individuals than there were twenty years ago; some …

Exploring Patterns Of Microhabitat Use Among Darters In The Lower Little River Watershed, Arkansas, Nate J. Martin, Savannah L. Wise

ATU Scholars Symposium

In this study, we seek to explore patterns of microhabitat use among darters, including variables of stream depth, water velocity, substrate composition, aquatic vegetation, and woody debris cover. The most informative microhabitat variables will be assessed using nonmetric multi-dimensional scaling (NMDS). Species with more than five individuals collected were included in analysis, totaling eight species across 24 sites in the Lower Little River Watershed of southwest Arkansas. We caught 28 Plains Darters (Etheostoma pulchellum), 27 Dusky Darters (Percina sciera), 21 Orangebelly Darters (Etheostoma radiosum), 16 Channel Darters (Percina copelandi), 13 Harlequin Darters (Etheostoma histrio), 11 Common Logperch (Percina caprodes), 7 …

Comprehensive Temporal, Spatial, And Environmental Analysis Of Arkansas Tournament Information Program (Atip) Data With A Lake Dardanelle Case Study., Jeffrey G. Phillips

ATU Scholars Symposium

The Arkansas Game and Fish Commission (AGFC) established the Arkansas Tournament Information Program (ATIP) in 1990 to provide a long-term, standardized dataset to describe Black Bass (Micropterus spp.) tournament outcomes, angler performance, and fish size structures across Arkansas, yet most of its analytical potential has not been fully explored beyond yearly summary reports. This project will use ATIP data from 1990 to 2027 and a biological case study from Lake Dardanelle to evaluate long-term trends, compare lake-specific performance, identify environmental drivers of tournament success, access how well tournament data represents true Black Bass populations, and create an “average” year benchmark …

Re-Purposing Pre-Existing Tilapia Aquaculture Open-Design System For Zebrafish Biomedical Research Purposes, Luke Cantu, David Sierra, Skyleigh Curtis, Maya Avila

ATU Scholars Symposium

Title: Re-purposing pre-existing tilapia open-design aquaculture systems for zebrafish biomedical research purposes.

Background: Zebrafish (Danio rerio) models are gaining popularity in biomedical research; however, the high infrastructure cost, at approximately $20,000 per unit, is a significant hurdle for primary undergraduate institutions (PUIs) establishing zebrafish facilities. This study assesses if repurposing existing tilapia open-design aquaculture systems could be a cost-effective method for zebrafish facility establishment.

Methods: Between November-2025 to February-2026, the study used a pre-existing tilapia aquaculture open-design system with personnel modified outlet filters. The water quality of this system was monitored and recorded. The study compared the stabilization phase or …

Conservation Gap Analysis Of The Endemic Flora Of Nevada (U.S.A.)​, Jodi D. Dunn

ATU Scholars Symposium

Introduction. Nevada is the driest state in the U.S. and spans multiple desert and montane biomes, containing over 3,000 species of plants across its varied environmental gradients. Within this flora, 268 species occur as regional endemics, with narrowly restricted distributions contained either fully, mostly, or partly within Nevada’s political boundaries. Preliminary investigation led us to hypothesize that most of the distributions of these rarities occur outside of currently protected areas. Methods. A list of endemic species was derived from the mentor’s work treating all Nevadan plants. Occurrence records with geographic coordinates were extracted into Excel spreadsheets. For occurrences without specified …

Fish Community Assessment Of Goose Pond Natural Area, Macy Sparks

ATU Scholars Symposium

Natural areas play an integral role in the preservation and conservation of unique ecosystems (i.e., natural wetlands). However, many natural areas have never had a biological inventory of species utilizing these areas. Goose Pond Natural Area (Conway County and Pope County, Arkansas) is one of those natural areas lacking species occurrence data. We addressed this data gap by sampling fish species across multiple habitat types (shallow woody wetland, open grassy wetland, and stream). We employed multiple gear types (mesh umbrella minnow traps, seines, gill nets, mini-fyke nets, and backpack electrofishing) in hopes of increasing species detection. Sites within the natural …

Using Environmental Dna To Locate Western Chicken Turtles In The Mississippi Delta Of Arkansas, Kai D. Scarangella

ATU Scholars Symposium

The Western Chicken Turtle (Deirochelys reticularia miaria; WCT) is a Species of Greatest Conservation Need in all six states where it occurs and is assumed to be rare and declining across its range. WCT are particularly vulnerable to habitat loss because their preferred shallow, wetland habitats are often subject to agricultural conversion and urban expansion. The conservation of this species is further hindered by its cryptic nature and prolonged aestivation, which make WCT notoriously difficult to locate and capture. Environmental DNA (eDNA), which is the genetic material that organisms naturally shed into their environment, can be detected by …

Colostrum Fatty Acid Composition And Its Association With Reproductive Traits In Sows Under Tropical Conditions, Dwi Sunu Datrianto, Kunaporn Homyog, Surasak Jittakhot, Padet Tummaruk

The Thai Journal of Veterinary Medicine

Colostrum provides essential nutrients and immune factors that newborn piglets can absorb only within the first 24 h after birth. Fatty acids are essential for neonatal physiology, supporting thermoregulation, neurodevelopment, and immune function, and serving as a key energy source to reduce hypothermia and mortality in piglets. However, information on the fatty acid composition of sow colostrum under tropical conditions and its relationship with reproductive performance remains limited, warranting further investigation to improve piglet survival. This study evaluated the fatty acid profile of sow colostrum under tropical production conditions and examined its associations with reproductive traits. Colostrum samples were collected …

Β-Glucan Mitigates Valproic Acid-Induced Hepatorenal Toxicity In Rats, Maha Mohammad Almutairi, Hussein Mohammad Ali, Mohamed Abdelbakky, Ahmad Hamad Alhowail

Saudi Toxicology Journal

Valproic acid (VPA) is a common medication used to treat epilepsy, known for its broad-spectrum efficacy but also associated with hepatotoxicity and metabolic disturbances. β-glucan, a natural polysaccharide with hepatoprotective properties, may mitigate druginduced liver damage. The study sought to assess hepatorenal toxicity of VPA and investigate the potential protective and therapeutic effects of β-glucan. Forty male rats were randomly distributed into four groups. The treated group received VPA (500 mg/kg), β-glucan (50 mg/kg), or combinations for 14–21 days via intraperitoneal injection. Serum biochemical parameters (ALT, AST, ALP, urea, creatinine, lipids) were measured. Histopathological evaluation of hepatic tissue was performed. …

Hydrologic History Regulates Microbial Biofilm Diversity And Ecosystem Function, Allison R. Rober, Leah C. Reese, Shawn P. Brown, Katherine D. Mcmahon, Stilianos Louca, Jillian Cieslik, Evan Kane, Merritt R. Turetsky, Kevin H. Wyatt

Michigan Tech Publications

Aquatic biofilms are an understudied component of northern peatlands and are expected to play a more prominent role in ecosystem processes in areas where aquatic habitat is expanding. The goal of this study was to investigate how hydrologic history influences biofilm diversity and functional genes. This study was conducted in a long-term water table manipulation that simulates drought (lowered water table treatment) and flooding (raised water table treatment) conditions relative to a control treatment (no manipulation). We used a combination of metabarcoding and metagenomic approaches to (1) examine the diversity of eukaryotic algae, cyanobacteria, bacteria and fungi within the biofilm …

Systematic Design And Optimization Of Porous Bone Plates Using Taguchi Method And Finite Element Analysis, Aliaa A. Farraj, Tawakol A. Enab, Hanan M. Amer, Mostafa A. Elbahloul

Mansoura Engineering Journal

Solid bone fixation plates, although clinically effective, often induce stress shielding and impair periosteal blood flow due to their mismatch in stiffness with cortical bone. To overcome these limitations, this study proposes lattice-engineered porous bone plates designed to balance mechanical integrity and biological compatibility. A systematic parametric investigation was conducted by varying three design variables: crystal structure type (diamond, fluorite, and gyroid), porosity levels (50%, 70%, and 90%), and structure layout. Three-dimensional models were developed using nTopology, and finite element analysis (FEA) was performed under a static compressive load to evaluate stress distribution. A Taguchi L9 orthogonal array was employed …

Harnessing The Gut-Diet Axis To Enhance Chemotherapy And Immunotherapy, Jill Carline

Bryant REDay (Research and Engagement Day)

The human microbiome, a complex ecosystem of trillions of microorganisms including bacteria, fungi, and viruses, represents a critical "gut-diet axis" that significantly influences cancer progression and therapeutic efficacy. While a state of homeostasis supports systemic immunity, dysbiosis is linked to chronic inflammation and can actively promote resistance to standard cytotoxic chemotherapies and modern immune checkpoint inhibitors. Specifically, research indicates that Bacteroides fragilis (ETBF) promotes resistance to 5-Fluorouracil and Oxaliplatin in colorectal cancer by activating Notch1 receptors to inhibit apoptosis and push cancer cells into a resilient, stem-cell-like state. Conversely, the introduction of fiber-rich and fermented foods can cultivate beneficial bacteria …

Reday Program 2026, Bryant University

Bryant REDay (Research and Engagement Day)

Program for the 2026 Bryant REDay (Research and Engagement Day). Program includes schedule at a glance, descriptions for panels, workshops, and presentations, along with sign-up links for specific sessions in the electronic version of the program. Printed program was in color with double-sided printing on 8 1/2" x 11" paper stapled together in the upper left corner.

Changes In Depression, Eating, Sleep, And Emotion Regulation In Air Force Rotc Cadets After The 12-Wk Star Training Program, Antonella V. Schwarz, Hunter Haynes, Sheena Puleali’I, Jacob Mota, Molly F. Johnson, Maria G. Kaylor, Andrew Addison, Robyn Braun-Trocchio, Austin J. Graybeal

Faculty Publications

Introduction: – Reserve Officer Training Corps (ROTC) cadets must balance collegiate demands with military preparation, leaving them vulnerable to psychological stressors. While structured strength and conditioning (S&C) programs enhance physical readiness, their impact on psychological health in cadet populations remains unclear. This study evaluated changes in depression, eating behaviors, sleep quality, and emotion regulation during a 12-wk S&C program. Methods: – Forty-nine U.S. Air Force ROTC cadets (21 female, 28 male; age: 20 ± 2 yr; body mass index: 24.2 ± 4.4 kg·m⁻²; body fat %: 27.1 ± 9.0%) completed the Supporting Tactical Athlete Readiness (STAR) program, a …

Does Volume Cycling Elicit A Skeletal Muscle Hypertrophy Re-Sensitization Effect? A Comparison Of Constant Versus Cycled Resistance Training Protocols, Joshua C. Pelland

Electronic Theses and Dissertations

Purpose: This study examined whether volume cycling in resistance training can elicit a skeletal muscle hypertrophy re-sensitization effect without muscle atrophy. We hypothesized that muscle size would be maintained during lower volume phases, that re-sensitization would occur following these phases, and that overall hypertrophy would be similar between cycled and constant volume conditions.

Methods: Thirty-seven trained men and women had their lower limbs randomized to either a constant volume (12 sets/week throughout) or cycled volume (alternating 4-week phases of 12 and 4 sets/week) condition for unilateral calf press training over 20 weeks. Lateral and medial gastrocnemius muscle thickness (MT), calf …