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Natural History Of The Porcine Bioprosthetic Heart Valve, Donald J. Magilligan Jr., Joseph W. Lewis Jr., J. Lancelot Lester Iii, Paul D. Stein, Mohsin Alam, Jeffrey B. Lakier, Julio C. Davilia, David W. Smith

Henry Ford Hospital Medical Journal

The porcine bioprosthesis has been the prosthetic valve of choice at Henry Ford Hospital since October 1971. By 1979, 23 cases of degeneration had been seen, and the rate seven years after implantation was 16%. Now, with a ten-year follow-up, there are 41 degenerated valves. After seven years, the percent free of degeneration is 88%, (SE of 2% [standard error]); at eight years, 82% (SE of 2.9%,); at nine years, 80% (SE of 3.4%); and at ten years, the percent free of degeneration is 69% (SE of 6.5%,). There was no difference in degeneration between men and women, between aortic …

Immunological Involvement In Porcine Bioprosthetic Valve Degeneration: Preliminary Studies, Rollin H. Heinzerling, Paul D. Stein, Jeanne M. Riddle, Donald J. Magilligan Jr., John J. Jennings

Henry Ford Hospital Medical Journal

Preliminary animal model studies have indicated that porcine bioprosthetic valves can be recognized by the immune system. This report presents the results of a preliminary investigation on the implanted valves of 27 patients. While none of the 27 demonstrated an immune response to porcine serum proteins, five patients developed antibodies against the implanted valve leaflets. Cells were enzymatically eluted from a degenerated bioprosthetic valve and were classified by means of monoclonal antibodies. Although these cells were not found to be of T-lymphocyte lineage, they did express la determinants and had the morphologic appearance of plasma cells. We therefore conclude that …

Agricultural Experiment Station News September 1982

Agricultural Research Division: News and Annual Reports

CONTENTS:
FROM THE DIRECTOR'S DESK
EXPERIMENT STATION SEMINAR
PROTECTION OF HUMAN SUBJECTS
PROGRESS AT THE GUDMUNDSEN SANDHILLS RESEARCH CENTER
25TH ANNIVERSARY AND FIELD DAY NORTHEAST STATION
SAHS SEZ
CALENDAR OF EVENTS
NEBRASKA AGRICULTURAL EXPERIMENT STATION PUBLICATIONS - August 1982

The Surgeon And The Patient With Cancer: The Development Of Surgical Oncology, Angelos A. Kambouris

Henry Ford Hospital Medical Journal

No abstract provided.

Memorials: Vincent H. Arthauld, Kenneth J. Drewry, David L. Mackintosh

Department of Animal Science: Faculty Publications

Vincent H. Arthaud, Professor Emeritus of the Animal Science Department, University of Nebraska, Lincoln, died at his home August 7, 1982. He was born September 7, 1911 at Cambridge, Nebraska and was reared on a general livestock farm in Southwest Nebraska. After receiving his B.S. degree in Animal Husbandry in 1936 from the University of Nebraska, he returned to his home area and engaged in general farming. He served with the U.S. Army from 1942 to 1945 and joined the Animal Science Department in 1945 as Research Farm Manager. He retired in 1977 following his many years of service as …

Dispermic Origin And Clinical Outcome Of Three Complete Hydatidiform Moles With 46,Xy Karyotype, U. Surti, A. E. Szulman, S. O'Brien

Biology Faculty Articles

Three new cases of complete, classic hydatidiform mole with a 46,XY karyotype are described. They originated by dispermy as demonstrated by chromosome and enzyme analyses. Levels of human chorionic gonadotropin decreased to normal spontaneously within a short time, indicating a benign course in these three cases. Of a total of 18 cases reported to date, postoperative clinical information was available for 10 patients. Two of these 10 patients had a malignant course with lung metastases. It is of theoretical and clinical importance to establish the magnitude of the risk of malignancy for hydatidiform mole with a 46,XY karyotype. © 1982.

Height, Weight, And Fertility Among Participants Of The Third Harvard Growth Study, Eugenie Scott, Carl J. Bajema

Peer Reviewed Publications

The relationship between weight, height, weigh/height² and fertility is examined in 610 females and 621 males from a 1968 follow-up study of the Third Harvard Growth Study participants. These subjects were born between 1912 and 1918 in the USA. Their physical and mental growth were studies for up to 12 years while they attended public schools in Boston Massachusetts, area. Height is not significantly related to fertility in either females or males, but weight and weight/height² is positively related to fertility in females (r = +.117 and + .100 respectively) and weight/height² is positively related to fertility …

Vol. 6 No. 1 (1982): Pacific Studies Front Matter, The Jonathan Nāpela Center For Hawaiian And Pacific Islands Studies

Pacific Studies

Pacific Studies is published two times a year by The Jonathan Nāpela Center for Hawaiian and Pacific Studies, Brigham Young University Hawai‘i #1979, 55–220 Kulanui Street, Lāʻie, Hawai‘i 96762, but responsibility for opinions expressed in the articles rests with the authors alone. Subscription rate is US$40.00 yearly, payable to The Jonathan Nāpela Center for Hawaiian and Pacific Studies. The Jonathan Nāpela Center for Hawaiian and Pacific Studies (formerly The Pacific Institute) is an organization funded by Brigham Young University Hawai‘i. The Center assists the University in meeting its cultural and educational goals by undertaking a program of teaching, research, and …

Vol. 6 No. 1 (1982): Pacific Studies Full Issue, The Jonathan Nāpela Center For Hawaiian And Pacific Islands Studies

Pacific Studies

Pacific Studies is published two times a year by The Jonathan Nāpela Center for Hawaiian and Pacific Studies, Brigham Young University Hawai‘i #1979, 55–220 Kulanui Street, Lāʻie, Hawai‘i 96762, but responsibility for opinions expressed in the articles rests with the authors alone. Subscription rate is US$40.00 yearly, payable to The Jonathan Nāpela Center for Hawaiian and Pacific Studies. The Jonathan Nāpela Center for Hawaiian and Pacific Studies (formerly The Pacific Institute) is an organization funded by Brigham Young University Hawai‘i. The Center assists the University in meeting its cultural and educational goals by undertaking a program of teaching, research, and …

Joseph P. Reser's Review Of R. L. Kirk's Aboriginal Man Adapting: The Human Biology Of Australian Aborigines, Joseph P. Reser

Pacific Studies

No abstract provided.

Books Received And Book Notices, The Jonathan Nāpela Center For Hawaiian And Pacific Islands Studies

Pacific Studies

Book Listing for the Vol 6, No 1 Fall Edition of the Pacific Studies Journal

Eugene Ogan's Review Of Solange Petit Skinner's The Nauruans, Eugene Ogan

Pacific Studies

No abstract provided.

The Prairie Naturalist Volume 14, No. 3. September 1982

The Prairie Naturalist

FECAL pH OF DESERT AND EASTERN COTTONTAIL RABBITS IN TEXAS ▪ R. J. Warren and K. T. Scribner

NESTING OF THE AMERICAN AVOCET IN NORTH DAKOTA ▪ J. G. Sidle and P. M. Arnold

REVISED CHECKLIST OF NORTH DAKOTA BIRDS ▪ C. A. Fannes and R. E. Stewart

THE EFFECT OF WEATHER FACTORS ON AUDUBON CHRISTMAS BIRD COUNTS L. L. Falk

NOTES:

Additional Nest Record for Red-breasted Nuthatch in North Dakota ▪ R. Hopkins

A Henslow's Sparrow in North Dakota ▪ R. B. Renken and J. J. Dinsmore

First Documented Record of the Moose in South Dakota ▪ D. A. …

Monoclonal Antibodies To Novel Myeloid Antigens Reveal Human Neutrophil Heterogeneity., Edward D. Ball, Robert F. Graziano, Li Shen, Michael W. Fanger

Dartmouth Scholarship

Three cytotoxic murine monoclonal antibodies that recognize myeloid-specific antigens have been produced by immunization with normal human neutrophils or myeloblasts from a patient with acute myelomonocytic leukemia. Two of these, PMN 6 and PMN 29, are specific for neutrophils; the third monoclonal antibody, AML-2-23, is reactive with the majority of normal monocytes as well as a subpopulation of mature neutrophils. Although neutrophils from all individuals tested expressed these antigens, cytofluorographic analysis revealed that the percentage of cells bearing the PMN 6 and AML-2-23 antigens varied among individuals. Significant additional heterogeneity in the density of each antigen among antigen-bearing cells was …

In Vivo Study Of The Effects Of Danazol On Cytoplasmic Receptors In The Female Rat, Deborah L. Spencer

Morehead State Theses and Dissertations

A thesis presented to the faculty of the School of Sciences and Mathematics at Morehead State University in partial fulfillment of the requirements for the Degree of Master of Science in Biology by Deborah L. Spencer on August 26, 1982.

Characterization Of Danazol Binding To Specific Cytosol Receptors In Vitro, Gail Wright Russell

Morehead State Theses and Dissertations

A thesis presented to the faculty of the School of Sciences and Mathematics at Morehead State University in partial fulfillment of the requirement for the Degree of Master of Science in Biology by Gail Wright Russell on August 26, 1982.

A New Column Perfusion Technique Using Isolated Rat Adrenal Cells To Study Acth And Danazol, Diane H. Johnson

Morehead State Theses and Dissertations

A thesis presented to the faculty of the School of Sciences and Mathematics at Morehead State University in partial fulfillment of the requirements for the Degree of Master of Science in Biology by Diane H. Johnson on August 15, 1982.

Aspects Of Anuran Metabolism: Effects Of Chronic Hypoxia On Maximal Oxygen Uptake Rates And The Fate Of Lactic Acid, Thomas Charles Solberg

Dissertations and Theses

Some aspects of anuran metabolism are examined, with special emphasis on possible limitations to aerobic metabolism and the effect of chronic hypoxia acclimation on maximal rates of aerobic metabolism and the metabolic fate of lactic acid accumulated after anaerobic metabolism.

The Influence Of Livestock Feed Size On Feed Consumption By Starlings (Sturnus Vulgaris), Daniel Twedt

Masters Theses & Specialist Projects

Ground meal and 4 sizes of pelleted feeds (3/16, ¼, 3/8 and ½ inch diameters) were offered to captive Starlings (Sturnus vulgaris, Linnaeus) to determine the minimum feed size they were unable to consume in significant amounts. The ground meal, 3/8 and ½ inch diameter pellets substantially decreased feed consumption compared with 3/16 and ¼ inch diameter pellets. Additionally, ½ inch pellets were consumed substantially less than ground meal or 3/8 inch pellets. Supplemental feed was require to prevent mortality among Starlings offered only ½ inch pellets.

Two pellet sizes, the 3/16 inch pellet which was readily consumed by …

Kentucky Warbler (Vol. 58, No. 3), Kentucky Library Research Collections

The Kentucky Warbler

No abstract provided.

Agricultural Experiment Station News August 1982

Agricultural Research Division: News and Annual Reports

CONTENTS:
From the Director’s Desk
Dean and Director Search and Selection
Vacation Time
Instrument Repair Service
Advisory Committee to Secretary Block
ARS Program Distribution
EXPERIMENT STATION ADVISORY COUNCIL
Grants and Contracts
NEBRASKA AGRICULTURAL EXPERIMENT STATION PUBLICATIONS - July 1982
Abstracts - Submitted for Publication
Calendar of Events - Summer, 1982

An Electrophoretic Comparison Of Gene Loci In Etheostoma Nigrum And Etheostoma Olmstedi From The James River Drainage, Virginia, Randall Keith Falls

Master's Theses

As many as five different populations of Etheostoma nigrum and Etheostoma olmstedi have been identified in the James River drainage, Virginia. Genetic variation of these populations was analyzed with starch gel electrophoresis and revealed only three distinct populations. Nine loci encoding five enzyme systems and two loci encoding muscle proteins were examined in tissue homogenates. All populations were monomorphic with the exception of the esterase-3 (Est-3), phosphoglucomutase (Pgm-1) and phosphoglucose isomerase (Pgi) loci. Two alleles of Est-3 exhibited activity in the homozygous and heterozygous conditions. Pgm-1 occurred as two alleles with a high degree of heterozygosity (46% for E. nigrum …

Fidelity Of Dna Polymerase In Vitro, Yannacos C. Philopoulos

Dissertations

The fidelity of DNA Polymerase I, isolated from B. licheniformis and B. stearothermophilus, was tested in the presence of carcinogens and anticancer compounds. All of these compounds inhibited (62.4-99.2%) the synthesis of DNA using Poly(dA-dT) as a template. The compounds were inhibitory at all concentration levels tested, 0.01, 1.0 and 100 mM. The fidelity of the enzyme appeared to be enhanced by the presence of these compounds, as indicated by misincorporation (50-70%), that is, the incorporation of incorrect nucleotide. Misincorporation in the presence of either carcinogens or anticancer compounds was less than that of control. The results from both organisms …

Hindlimb Immobilization: Length-Tension And Contractile Properties Of Skeletal Muscle, Frank Arthur Witzmann, D. H. Kim, Robert H. Fitts

Biological Sciences Faculty Research and Publications

The effect of hindlimb immobilization (IM) on the contractile properties of fast and slow skeletal muscle was studied in rats following various periods of IM ranging from 1 to 42 days; muscle atrophy, muscle, fiber, and sarcomere length, and the length-tension characteristics were determined after 42 days of IM. The slow-twitch soleus (SOL), the fast-twitch extensor digitorum longus (EDL), and the fast-twitch superficial region of the vastus lateralis (SVL) all showed rapid atrophy following the onset of IM, reaching a new reduced steady-state weight by day 21. After 42 days of IM the passive tension (g) and active twitch …

Host Range Of Southern Corn Billbug (Coleoptera: Curculionidae) Adults And Larvae, Robert J. Wright, J. W. Van Duyn, J. R. Bradley Jr.

Department of Entomology: Faculty Publications

Host range of the southern corn billbug, (SCB), Sphenophorus callosus (Olivier) (Coleoptera: Curculionidae), was tested with 14 crop and weed species by artificially infesting plants with SCB adults and eggs; field observations were also made. Of 14 species tested, only corn, Zea mays L., and yellow nutsedge, Cyperus esculentus L., allowed completion of larval development, although adults fed on a wider variety of plants. Scirpus cyperinusI, (L.) Kunth (Cyperaceae) was found to be a new SCB larval host from field observations. Overwintered SCB adults were fed sections of greenhouse-grown corn and four weed species in the laboratory. Survival was highest …

Review Of Phylogenetics: The Theory And Practice Of Phylogenetic Systematics, By E. O. Wiley (Wiley-Interscience, 1981; 439 P.), Daniel R. Brooks

Harold W. Manter Laboratory of Parasitology: Faculty Publications

A book review by Daniel R. Brooks of Phylogenetics: The Theory and Practice of Phylogenetic Systematics, by E. O. Wiley (Wiley-Interscience, 1981; 439 p.).

A Histopathological Study Of The Effect Of Ethylnitrosourea On Ha(Icr) Mice Testes, Mildred Rodriguez

Masters Theses

Ethylnitrosourea (ENU) is very strongly mutagenic, carcinogenic and teratogenic in mice. In the present study ENU was used to induce germ cell damage in the mouse testis. Mice were given single injections of vehicle, 50, 100, or 200 milligrams of ENU per kilogram of body weight and killed at various times over a fifteen week period. Microscopic examination of the testes showed that extensive killing of spermatogonial cells and therefore maturation depletion had occurred in the seminiferous tubules. The histopathology was dose dependent and the testicular weight decreased with an increasing ENU concentration.

The Ecology Of The Mottled Sculpin, Cottus Bairdii, In The Clearwater River, Beltrami County, Minnesota, Mark A. Hanson

Biology Graduate Theses

No abstract provided.

The Relationship Between Chemical Leavening Agents And Three Gastric Indices In Rats Subjected To Restraint Stress, Holly E. Bartelmann

Loma Linda University Electronic Theses, Dissertations & Projects

Male Sprague-Dawley rats fed diets of enriched yeast-leavened biscuits had no discernible advantage over those fed enriched chemically-leavened biscuits in three gastric indices studied. Restraint-stress administered to half of each dietary group was ineffectual in producing gastric ulcers, but did produce gastric color and appearance changes in fifty-eight per cent of the group receiving the chemically-leavened diet.

Thiamin and riboflavin-retention analyses done on various baked products produced conflicting results. Yeast-leavened products retained less thiamin and riboflavin than chemically-leavened products, but which chemical leavening agent was best for vitamin retention was different for each vitamin.

Anuran Activity Energetics, Scott R. Landrey

Dissertations and Theses

This thesis presents two separate experiments concerning aerobic and anaerobic amphibian energetics. The first study (Part I) investigates differential alterations in the kinetics of the anaerobic enzyme lactate dehydrogenase, in nine species of anurans with varying natural histories. The second study (Part II) studies changes in different anaerobic and aerobic physiological parameters in a single species (Rana catesbeiana) after six weeks of chronic exercised, unexercised-captive and for field frogs. The common theme of these two experiments involves the potential for physiological changes due to environmental stress. Part I examines different species to infer a possible evolutionary relationship to …