Digital Commons Network^™

The Effects Of A High-Carbohydrate Versus A High-Fat Shake On Heart Rate Variability When Used To Interrupt A 38-Hour Fast, Dane Jensen, Cameron Jacobsen, Landon Deru Ph.D., Elizabeth Z. Gipson, Katelynn E. Hales, Bruce W. Bailey Ph.D.

Library/Life Sciences Undergraduate Poster Competition 2025

(HRV) is a biological phenomenon that refers to the variations in the time intervals between heartbeats and is commonly used to assess vascular health. Heart rate variability (HRV) indicates the heart’s capacity to respond to stimuli from the autonomic nervous system. High HRV has been known to be correlated with a healthy heart and autonomic nervous system, while low HRV has been known to be correlated with adverse physiological conditions [6]. While previous research has explored the cardiovascular effects of fasting and food intake, the impact of the post-fast meal on cardiovascular health remains understudied. This study aims to investigate …

Taking Out The Taxonomic Trash: Refining Skink Classification In The Genus Sphenomorphus, Phillip Cockrell, Leah Stimpson, Alison Whiting Ph.D

Library/Life Sciences Undergraduate Poster Competition 2025

Distributed in New Guinea, Wallacea, Indonesia, and SE Asia (see figure 2), Sphenomorphus is often called a “Waste Bin” genus because species that don’t fit elsewhere are “dumped” there.

These cryptic skinks (see figure 1) have been problematic for traditional taxonomy due to a lack of discrete morphological characters.

Recent molecular studies of Sphenomorphus in the Philippines find the genus to be paraphyletic.

New Guinea has one of the largest concentrations of Sphenomorphus, has been poorly studied (figure 4), and is known for its extreme biodiversity¹,².

We seek to test the monophyly of Sphenomorphus in New Guinea, and the …

Research Process Toward The Creation Of Transgenic Beetles, Taylor Coffman, Christian Mccombs, Jonah Jex, Chris Daley, Brian D. Jensen, Sandra Hope Ph.D

Library/Life Sciences Undergraduate Poster Competition 2025

Create a generalized efficient procedure for the reliable creation of transgenic insects.

Optimizing Carbon Nanotube Diameter And Copper Coating To Inhibit Pseudomonas Aeruginosa Biofilm Growth, Owen Cramer, Jenny Finlinson, Lucy C. Bowden, Bradford K. Berges Ph.D.

Library/Life Sciences Undergraduate Poster Competition 2025

• ~30% of surgical implant failure is caused by infection¹
• 10-23% of all implant-associated bone and joint infections are caused by gram-negative bacteria²
• Pseudomonas aeruginosa, a gram-negative bacterium, forms biofilms (bacterial communities encased in a matrix) that are extremely difficult to treat
• Carbon-Infiltrated Carbon Nanotubes (CICNT) have a surface structure that prevents the formation of biofilms³
• The mechanism of biofilm disruption on CICNT is still unknown.
• Our current research is focused on creating the optimal CICNT conditions that result in the greatest reduction of adherent P. aeruginosa.

Invasive Species And Water Loss: Automating The Study Of Phragmites In Utah Wetlands, Alexander Atkinson, Dr. Rachel Wood

Library/Life Sciences Undergraduate Poster Competition 2025

Phragmites australis is an invasive reed threatening Utah wetlands by not only outcompeting native flora and disrupting ecological system but also potentially increasing evapotranspiration (ET), the combined process of evaporation and plant transpiration. Increased ET may accelerate water loss in the already shrinking Great Salt Lake (GSL), exacerbating ecological and economic consequences.

To address this, we are developing an automated R-based data analysis pipeline to analyze Utah Geological Survey (UGS) data at the GSL Phragmites site, and to validate evapotranspiration measurements with satellite estimates from OpenET. By making the data and analyses easily accessible, we can better understand and mitigate …

Effect Of Isostatic Rebound On Soil Biodiversity, Robert Candland, Blake Harrison, Solinus Farrer, Kyle Lake, Byron Adams

Library/Life Sciences Undergraduate Poster Competition 2025

Purpose: Understand the effect of shifting tide lines on organism diversity and abundance

Ms Environmental Biology Capstone Project, Emily A. Patton

Regis University Student Publications (comprehensive collection)

This is a masters Thesis for MS in Environmental Biology containing four chapters including a literature review, grant proposal, journal manuscript, and stakeholders report on a current environmental issue. (1) Noise Pollution and Avian Communication in Urban Ecosystems: When the Natural World Struggles to Hear Itself. Urban noise masks essential bird vocalizations, which harms avian fitness. Most species are displaced, and those few urban birds which counteract this noise with song adaptations likely experience trade-offs. America's noise policy remains undeveloped, threatening the health of both humans and avian wildlife (2) Application of Noise Barrier Technology for the Restoration of Urban …

Parthenogenetic Pathways: Investigating The Expansion Of A Clonal Whiptail, Jordan Kirk, Vicente Fernandez Lara, Angelina Romero, Dallin Matthews, Reagan Mckee, Randy Klabacka

Library/Life Sciences Undergraduate Poster Competition 2025

Non-native species are defined as species who live in any area outside of their native range, and they often have unique adaptational strategies to be able to populate various areas, even those different from their native habitat

The New Mexico Whiptail (Aspidoscelis neomexicanus) is a parthenogenetic (asexual) species of lizard of family Teiidae. It’s native range extends from central to south-central New Mexico [1]

Parthenogenetic species can colonize/invade new territories easily due to their ability to reproduce asexually [4]

Established populations of this species of lizard in multiple localities outside of their native range have been identified in …

The Effects Of Exosomes In Lead And Lps Induced Inflammation In Microglia, Yitzchak Lax

Theses and Dissertations

Exosomes are membrane bound subcellular vesicles formed through membrane budding of a cell and play important roles in cell-cell communication. Studies have demonstrated inflammatory changes in various cell types depending on the etiology of the exosomes such as exosomes from cancer cells or exosomes derived from mesenchymal stem cells. The purpose of this study was to determine the inflammatory consequences of exosomes in microglial cells following exposure to lead, lipopolysaccharides (LPS) and lead+LPS. The cultured mouse microglial cells were treated at 0.01 μM, 0.1 μM and 1 μM of lead,- three environmentally relevant levels and LPS was used at 10 …

Aligning Exons, Introns, And Flanking Regions Of Cyc And Cuc Genes In Lonicera (Caprifoliaceae), Mark Mordukhay

Theses and Dissertations

The genus Lonicera (Caprifoliaceae) exhibits great diversity in floral symmetry, petal fusion, and organ arrangement, making it an ideal system for exploring the genetic basis of morphological evolution. We focus here on the roles of CYC and CUC gene families, (CYC2A, CYC2B, CYC3A, CYC3B, CUC2A, and CUC2B) and their potential contributions in shaping floral symmetry and organ fusion. The data set included nucleotide sequences from over 90 Lonicera species, extracted from samples collected from natural habitats or herbaria and then sequenced. A custom bioinformatics pipeline was developed in R using Bioconductor packages to automate BLAST searches, filter results, scan for …

Analysis And Authentication Of An Optical Method For Early Detection Of Harmful Algal Blooms, Cody Schumacher

Theses, Dissertations and Capstones

The proliferation and frequency of harmful algal blooms (HABs) attributed to eutrophication, storm events and a changing climate have been an increasing concern in both lotic and lentic freshwater ecosystems. Methods of detecting HABs have been explored through fluorescent measurement and sample analysis, but are often expensive and time-consuming. A novel smart device application is in development to detect HABs based on images captured and analyzed by machine learning algorithms trained to distinguish potential cyanobacterial blooms. The HABs App model accurately detected cyanobacteria in strong relationship with biovolume concentrations (R² = 0.996) within the Greenup Pool of the Ohio …

Evaluating Genetic Variation Of Brassica Tournefortii Gouan Collections Via Microsatellite Marker Analysis, Brian Alfaro, Thomas F. Turner, Diane L. Marshall

Aliso: A Journal of Systematic and Floristic Botany

Plants can differ in phenotypes, but genetic variation may not always reflect phenotypic differentiation. In this study, we tested if native, invasive and landrace population types of Brassica tournefortii Gouan diverged genetically. We performed this comparison by genotyping individuals derived from our own field collections (invasive populations) and from USDA accessions (plants from the native range and landraces). We used two polymorphic microsatellite loci to analyze allelic diversity (Question 1), genetic differentiation, admixture, inbreeding (Question 2) and evolutionary relationships (Question 3) of three population types and of 17 populations of B. tournefortii. Comparison of allelic diversity indices and observed …

Components Of Evolutionary Psychology Are Falsifiable, But Does That Make It A Good Theory? Commentary On Costello Et Al. (2025), David S. Moore

Pitzer Faculty Publications and Research

At the center of narrow evolutionary psychology’s theory lies the assumption that many human behavioral mechanisms evolved via natural selection. Although some components of this theory are falsifiable, its Lakatosian framework protects its core assumptions from falsifiability, even though most human behaviors probably do not require evolutionary explanations. Crucially, falsifiability is a necessary but insufficient quality of a good scientific theory, and the value of narrow evolutionary psychology (NEP) can be questioned on other grounds. NEP holds that only natural selection can create complex, functional adaptations, but natural selection is not a creative force; this process merely functions as a …

Soil Amendments Alter Tree Growth And Wood Decay After Forest Thinning, Deborah S. Page-Dumroese, Martin Jurgensen, Chris Miller, Joanne M. Tirocke, Derek N. Pierson, Cole Mayn, Mark J. Kimsey, Haley C. Anderson

Michigan Tech Publications

Forest soil amendments are increasingly used in western US forests to dispose of unmerchantable woody residues, reduce wildfire risk, and improve soil properties. Our objective was to determine the effect of fertilizer and organic amendments on tree growth and organic matter decomposition after thinning. Treatments were a control, three single soil amendments (wood chips, fertilizer, and biochar), and one combined soil amendment (biochar + fertilizer), each applied after thinning a ponderosa pine (Pinus ponderosa Dougl. ex. Laws) stand. After 10 years, amendment treatments had no effect on tree diameter increment (p = 0.600), but the biochar + fertilizer and wood …

An In Vivo Study Of Lns8801, A Gper Agonist, In A Spontaneous Melanoma-Prone Mouse Model, Tgs., Christina Marinaro, John Sauer, Christopher A Natale, Todd Ridky, Suzie Chen

Rowan-Virtua School of Osteopathic Medicine Departmental Research

Melanoma is the most aggressive and deadly form of skin cancer that arises from the transformation of melanocytes, the pigment producing cells of the skin. In the year 2024 there will be approximately 10,000 new cases of melanoma diagnosed and approximately 8,000 deaths attributed to melanoma in the United States. In this study we treated a group of male and female transgenic mice that spontaneously develop metastatic melanoma, TGS, with a G-protein-coupled estrogen receptor agonist LNS8801 to assess the efficacy on disease progression. A second group of male and female TGS mice was also exposed to UVB irradiation to mimic …

Anti-Cancer Compounds Based On Natural Imidazole Compounds, Autumn Forsythe, Victoria Hardy, Kerri L. Shelton

CSU Tower Day

We are developing a comprehensive review on imidazole-based compounds of natural origin, the most common groups of compounds, and their properties, such as the imidazole ring. The intent of this presentation is to learn about the compound’s occurrence, general/predicted properties, and advantages. The review will be a fluid development comparing imidazole derivatives of natural origin with antinociceptive/lethal properties from the last 5 years. This review would include both purely extracted products but also those modified by synthesis.

The Involvement Of Camp In The Secretion Of Il-10, Jyanna J. Mendola

SURF Posters 2025

Schwann cells have been found to play a key role in inflammation and repair following nerve injury. During nerve injury, the myelin sheath becomes damaged, stimulating Schwann cells to secrete cytokines and initiate an inflammatory response. They begin the process of repair by stimulating macrophages to make pro-inflammatory cytokines, such as Tumor Necrosis Factor-Alpha (TNF-a), and anti-inflammatory cytokines, such as Interleukin 10 (IL-10) which promotes healing and injury. Although it is clear Schwann cells play a role in nerve repair, there is still yet to be known regarding the exact mechanisms by which they do so. In vitro, Lipopolysaccharide (LPS), …

Ludwigia Hydrology Study, Rebecca E. Drenovsky, Rebecca Reicholf, Caryn J. Futrell*, Brenda Grewell*, Blanca Gallego-Tévar

Ludwigia Hydrology Study

Premise: Hydrological regime influences wetland plant species distribution and performance.Global warming and extreme weather events are magnifying flooding patterns, and understanding how invasive taxa respond across life stages (establishment vs. established phase) is important for predicting and managing their colonization and spread. Our objective was to measure flood trait responses at contrasting life stages in closely related congeners (Ludwigia peploides, diploid; L. hexapetala, decaploid; Onagraceae) differing in their invasiveness in the field.

Methods: In the field, we assessed phenological responses to seasonal hydrological changes, and in mesocosms, we assessed flood stress responses of establishing shoot fragments under deep-flooded, …

The Effect Of Two Common Herbicides On The Growth And Development Of Two Anuran Species (Boreorana Sylvatica And Dryophytes Chrysoscelis), Jerica Eaton

Masters Theses & Specialist Projects

Amphibian populations have been declining globally since the 1950s. Many species that have experienced declines are viewed as 'environmental indicators' that reveal habitat degradation. Declines can be attributed to several factors, including chemicals used in agriculture, such as Roundup and Atrazine. Agrochemicals contaminate water bodies through runoff or leaching and cause alterations to aquatic ecosystems. This study evaluated the effects of herbicide usage on two wild anuran populations using wood frogs (Boreorana sylvatica) and Cope’s gray tree frogs (Dryophytes chrysoscelis) as a model. We determined the effect of the herbicides at two concentrations, a high concentration …

Ms Environmental Biology Capstone: Evaluating Environmental Risks And Conflicts In Golf Course Landscapes, Meredith Boos

Regis University Student Publications (comprehensive collection)

1) This review investigates the relationship between pesticide use on golf courses and in agriculture to determine whether the adverse health effects documented in agricultural settings also apply to golf course environments. While the negative health effects from agricultural pesticide use are well established, golf courses use pesticides with greater frequency and intensity, suggesting a potentially higher exposure risk for both workers and players.

2) This study proposes methods to quantify pesticide bioaccumulation on golf courses and adjacent lands. We hypothesize that areas surrounding golf courses will exhibit a spatial gradient of pesticide accumulation, increasing with proximity to treated sites …

Navigating Cultural Differences In Community-Based Conservation: A Malagasy Case Study, Austin J. Cheng

CISLA Senior Integrative Projects

This SIP explores the tension between avoiding cultural imperialism and remaining true to ideals, particularly of gender equality in the creation and funding of community-based conservation organizations in patriarchal societies. To tether these loftier ideas to practice, I use my internship with Planet Madagascar in Ankarafantsika National Park as a case study, and explore it through the lenses of feminist, pragmatist, and post-colonial philosophers.

Engineering Chimeric Autoantibody Receptor T Cells (Caar): A Potential Cure For Graves' Disease, Kimbal Demars, Abigail Cheever, Chloe Kang, Hunter Lindsay, Mackenzie Hansen, Kim O'Neill, Scott Weber

Library/Life Sciences Undergraduate Poster Competition 2025

• Graves’ Disease (GD) is the 4th most common autoimmune disease in the United States.
• GD is characterized by autoreactive B cells releasing anti-thyroid stimulating hormone receptor (TSHR) Ab that bind to TSHR, causing an overexpression of hormones.
• Excessive hormonal release leads to hyperthyroidism, causing a variety of metabolic issues.
• No cure exists, only limited effectiveness of treatments, including chemotherapy, radiation, or thyroidectomy.
• Chimeric antigen receptors (CAR) T cell therapy has been effective in treating blood cancers.
• Modifying this therapy by engineering T cells that replace the antigen as the T cell receptor will selectively target autoreactive B cells, namely chimeric …

End Epilepsy: Human And Rodent Seizures Demonstrate A Dynamic Interplay With Spreading Depolarizations, Daniel Hummel, Jacob H. Norby, Noah Ricks, John D. Rolston, Shervin Rahimpour, Juha Voipio, Andrew J. Trevelyan, Elliot H. Smith, Ryley Parrish

Library/Life Sciences Undergraduate Poster Competition 2025

Affecting more than 50 million people worldwide, Epilepsy is a condition of repeated seizures. Seizures (Sz) occur when brain cells transmit uncontrolled electrical signals, and most often terminate on their own, but how this happens is unknown. A proposed mechanism of Sz termination is a spreading depolarization (SD). A SD is a wave that travels through the brain, suppressing brain activity. Currently, the relationship between SDs and seizures is not well understood. The goal of this study was to understand how the two phenomena interact in both rodent brains, and humans. Better understanding of SDs may lead to the development …

Enabling Better Interoperability And Reusability For Down Syndrome Transcriptomic Datasets, Harrison Oaks, Garrett L. Wride, Stephen Piccolo

Library/Life Sciences Undergraduate Poster Competition 2025

Introduction: Gene expression profiling has become a cornerstone of biomedical research, offering relevant insights into the molecular mechanisms that underlie complex conditions such as Down syndrome (DS), a condition caused by trisomy 21. RNA expression data from individuals with DS have highlighted critical pathways involved in development, immune function, and disease susceptibility. Despite the availability of over 100 publicly shared RNA expression datasets, their potential remains underutilized due to inconsistent metadata, diverse normalization protocols, and varying data quality. Addressing these barriers is vital to enabling researchers to standardize, integrate, and analyze datasets effectively. We do this by creating a data …

Effects Of Predation On Cognition In Brachyrhaphis Rhabdophora, Elizabeth F. Jenkins, Jerald B. Johnson

Library/Life Sciences Undergraduate Poster Competition 2025

Does predation environment affect the cognitive abilities of the tropical fish Brachyrhaphis rhabdophora?

Effects Of Ethanol On G-Csf Sensitivity In The Ventral Striatum, Kaleb Gardner, Rachel Campbell, Camryn Holt, Zachary Valentine, Chase Seiter, Jordan T. Yorgason

Library/Life Sciences Undergraduate Poster Competition 2025

Granulocyte-colony stimulating factor (G-CSF) is a known neuromodulator for dopamine (DA) release in the ventral striatum • Increased peripheral G-CSF levels enhances abused substance effects • The G-CSF mechanism for enhancing release remains unknown • How ethanol affects G-CSF neuromodulation also remains unknown • The present studies examined G-CSF effects on striatal and mesolimbic circuitry and chronic ethanol effects on this system

Effects Of Acute Injections Of Etoh In Cytokine Release In Mice, Alina Svitlana Rodriguez Bezruchko, Alka Gaur, Carlos M. Moreno, Jordan T. Yorgason, Scott Weber

Library/Life Sciences Undergraduate Poster Competition 2025

To learn the pathway by which the peripheral immune system interacts with dopaminergic neurons and triggers an addiction response, we compared cytokine and chemokine production levels before and after a 20-minute ethanol injection. Since some cytokines and chemokines can cross the blood-brain barrier, their peripheral production may influence neural activity. We had four groups: ethanol, saline, domperidone-ethanol, and domperidone-saline. As domperidone is a dopamine antagonist, we will use it as a control to verify that the change in cytokine production is due to ethanol rather than other factors.

Developement Of A Rodent Virtual Reality System For Measuring Reward, Aman Malhotra, Joe Davis, Jacob Cecil, Lauren Ford, Daniel-Luke Isemonger, Noah Moffat, Ryan Powers, Cody Siciliano, Ryan West, Jordan T. Yorgason

Library/Life Sciences Undergraduate Poster Competition 2025

Rodent VR is a tool for drug impact studies involving VR and optical imaging on motivation-related circuits using customizable maze creation and a comprehensive analysis program. We are using this combined with a GRINS lens surgical implant to gather real time data.

Competitive Bacteria Inhibiting Yersinia Ruckeri Growth – A Strategy To Prevent Enteric Redmouth Disease (Erm) In Freshwater Fish, Kyler Linton, David Erickson

Library/Life Sciences Undergraduate Poster Competition 2025

Pacific freshwater fish are less likely than Atlantic freshwater fish to exhibit Enteric Redmouth Disease (ERM), or Yersiniosis as caused by Yersinia ruckeri. Based on the hypothesis that these fish may harbor commensal bacteria that inhibit Y. ruckeri growth, we isolated many kinds of commensal bacteria from fish intestines that we have collected from Alaska and local streams. Using co-culture experiments, we have conducted competitive assays to determine if the bacteria found in the gut biomes of these fish inhibit the growth of Y. ruckeri. These may be potential probiotic organisms that could provide resistance to ERM disease.

Comparative Whole Genome Sequencing Of Cryopreserved And Ffpe Cancer Tissue, Delaney Anderson, Ken Dixon, Ryan Miller, Sangmoon Lee, Jeffrey Okojie, Jared Barrott

Library/Life Sciences Undergraduate Poster Competition 2025

Whole genome sequencing (WGS) determines the DNA sequence of an organism’s entire genome & plays a key role in cancer precision medicine

• Currently, the main preservation method of cancer tissue for WGS is formalin-fixed, paraffin-embedded (FFPE) tissue; cryopreserved (CP) tissue is not routinely used in clinical settings
• Previous studies have determined CP tissue yields higher quality & quantity of DNA
• This study aimed to compare the outcomes of WGS in CP & FFPE samples.