Digital Commons Network^™

A Multidomain Peptide Hydrogel-Liposome Composite For Controlled Release Of A Cyclic Dinucleotide In Oral Cancer, Joseph W R Swain, Andrea H Molina, Gemalene M Sunga, Danielle Chew-Martinez, Neeraja Dharmaraj, Alejandra Cobos Perez, Arghadip Dey, Ephraim J Vázquez-Rosado, Simon Young, Jeffrey D Hartgerink

Faculty, Staff and Student Publications

While immunotherapy is a promising treatment strategy for cancer, the majority of head and neck squamous cell carcinoma (HNSCC) patients treated with single-agent immunotherapy do not respond. Therefore, researchers are investigating combination treatments with immunostimulatory molecules that can maximize anti-tumor responses. Cyclic dinucleotides (CDNs) are STING agonists that hold promise in combination approaches, but they require frequent intratumoral administration when used in both preclinical models of HNSCC and clinical trials. To reduce administration frequency, we have created a peptide hydrogel–liposome composite system, K2-Lip(CDN), for local and prolonged availability of CDN. We investigated the loading limits of cationic liposomes in both …

Structural Transformation Of A Hydrogel-Forming Cell Division Protein Zapb Of Multidrug Resistant Klebsiella Pneumoniae With Small Molecules, Ayesha Khan, M. Iqbal Choudhary, Sumaira Javaid, Humaira Zafar, Innokentiy Maslennikov, Atia-Tul Wahab

Pharmacy Faculty Articles and Research

Septal ring assembly protein ZapB (EMR18431.1) is involved in Z-ring formation, and nucleoid segregation during the bacterial cell division . It promotes cell division in the initial stages of the cell cycle through direct interaction with FtsZ, thus stimulating Z-ring assembly. The ZapB inhibition can make bacterial cell susceptible to primary antibiotics, and therefore considered as an important approach for adjuvent therapy against MDR bacterial infections. Hence in the current study, ZapB protein of multidrug resistant Klebsiella pneumoniae was cloned, and expressed in E. coli system. To understand its role, and to assess the mechanism of ZapB activation, the characteristic …

Grassland Bird Community Responses To Fire Management, Mason H. Dillard

ATU Scholars Symposium

Vegetation structure plays a major role in determining avian community makeup. Controlled burn frequency changes vegetation structure and consequently the makeup of avian communities. To examine this relationship, I surveyed breeding birds in grasslands and savannahs of the Ozark Mountains, Arkansas River Valley, and Northwest Arkansas. I created models to outline the relationship between these three factors (avian community, fire management, and vegetation structure.) I also examined surrounding land cover and patch size as potential variables that may impact avian community structures.

I will outline the role fire management plays in determining the makeup of breeding bird communities in grasslands, …

Colostrum Fatty Acid Composition And Its Association With Reproductive Traits In Sows Under Tropical Conditions, Dwi Sunu Datrianto, Kunaporn Homyog, Surasak Jittakhot, Padet Tummaruk

The Thai Journal of Veterinary Medicine

Colostrum provides essential nutrients and immune factors that newborn piglets can absorb only within the first 24 h after birth. Fatty acids are essential for neonatal physiology, supporting thermoregulation, neurodevelopment, and immune function, and serving as a key energy source to reduce hypothermia and mortality in piglets. However, information on the fatty acid composition of sow colostrum under tropical conditions and its relationship with reproductive performance remains limited, warranting further investigation to improve piglet survival. This study evaluated the fatty acid profile of sow colostrum under tropical production conditions and examined its associations with reproductive traits. Colostrum samples were collected …

Guide To The International Pinot Noir Celebration (Ipnc) Collection, Linfield College Archives

Linfield Archives Finding Aids

This collection contains documents, photographs, digital media, artifacts, and real objects of the IPNC from the beginning of the conference’s origins in 1987 through the present day. Included are invitations, newspaper articles, reviews, correspondence between IPNC and wineries, advertisements, magazines, letters, meeting summaries, photographs, negatives, posters, exhibition material, objects that relate to the IPNC, and CDs with digital content.

Basket Flower Cut Flower Production In Utah, Kellie Webb, Melanie Stock, Amanda Pratt, Claudia Nischwitz, Nick Volesky

All Current Publications

Basket flower is a versatile and visually striking plant valued by florists and gardeners alike for its unique texture, ease of cultivation, and environmental benefits. The large, fringed blooms in shades of pink, lavender, and creamy white add elegance and texture to floral arrangements, harmonizing well with other flowers and greenery. As a reliable mid-season, low-water annual, this crop thrives across soil types with minimal maintenance, making it an excellent choice for U.S. Intermountain West growers. Moreover, its ability to attract pollinators, such as bees and butterflies, enhances its ecological value, while its resistance to pests and diseases further contributes …

Gomphrena Cut Flower Production In Utah, Kellie Webb, Melanie Stock, Cheyenne Reid, Victoria Xiong, Benjamin Scow, Amanda Pratt, Claudia Nischwitz, Nick Volesky

All Current Publications

Gomphrena, also known as globe amaranth, is a full-sun annual with clover-like, papery blooms. Plants thrive in the heat and prefer drier soils once established, making this crop a water-wise choice for Utah cut flower production. Blooms range from soft to fluorescent pink, white, orange, lilac, and red. Gomphrena is especially useful in detailed design work, such as boutonnieres and corsages, as the blooms do well out of water. Gomphrena is also an exceptional flower for drying. The versatility of selling gomphrena as both a fresh and dried cut flower increases its value for Utah growers. Grown primarily for field …

Strawflower Cut Flower Production In Utah, Melanie Stock, Ali Harrison, Lorin Harrison, Cheyenne Reid, Victoria Xiong, Benjamin Scow, Claudia Nischwitz, Nick Volesky

All Current Publications

Strawflower is a cut-and-come again, full-sun annual that performs well with reduced irrigation. Often called the “everlasting flower” and “paper flower,” the dry, daisy-like blooms range from earthy salmon and terracotta to white and dusky blush tones. Strawflower adds texture to floral design, and the diverse color palette is attractive to florists. This cut flower is also exceptional for drying, as it is nearly dried in the field when ready for harvest. The non-fussy growth, low resource use, branching habit, and easy harvest make strawflower an excellent field crop in the U.S. Intermountain West, though expected yields may be lower …

Systematic Design And Optimization Of Porous Bone Plates Using Taguchi Method And Finite Element Analysis, Aliaa A. Farraj, Tawakol A. Enab, Hanan M. Amer, Mostafa A. Elbahloul

Mansoura Engineering Journal

Solid bone fixation plates, although clinically effective, often induce stress shielding and impair periosteal blood flow due to their mismatch in stiffness with cortical bone. To overcome these limitations, this study proposes lattice-engineered porous bone plates designed to balance mechanical integrity and biological compatibility. A systematic parametric investigation was conducted by varying three design variables: crystal structure type (diamond, fluorite, and gyroid), porosity levels (50%, 70%, and 90%), and structure layout. Three-dimensional models were developed using nTopology, and finite element analysis (FEA) was performed under a static compressive load to evaluate stress distribution. A Taguchi L9 orthogonal array was employed …

Reday Program 2026, Bryant University

Bryant REDay (Research and Engagement Day)

Program for the 2026 Bryant REDay (Research and Engagement Day). Program includes schedule at a glance, descriptions for panels, workshops, and presentations, along with sign-up links for specific sessions in the electronic version of the program. Printed program was in color with double-sided printing on 8 1/2" x 11" paper stapled together in the upper left corner.

Changes In Depression, Eating, Sleep, And Emotion Regulation In Air Force Rotc Cadets After The 12-Wk Star Training Program, Antonella V. Schwarz, Hunter Haynes, Sheena Puleali’I, Jacob Mota, Molly F. Johnson, Maria G. Kaylor, Andrew Addison, Robyn Braun-Trocchio, Austin J. Graybeal

Faculty Publications

Introduction: – Reserve Officer Training Corps (ROTC) cadets must balance collegiate demands with military preparation, leaving them vulnerable to psychological stressors. While structured strength and conditioning (S&C) programs enhance physical readiness, their impact on psychological health in cadet populations remains unclear. This study evaluated changes in depression, eating behaviors, sleep quality, and emotion regulation during a 12-wk S&C program. Methods: – Forty-nine U.S. Air Force ROTC cadets (21 female, 28 male; age: 20 ± 2 yr; body mass index: 24.2 ± 4.4 kg·m⁻²; body fat %: 27.1 ± 9.0%) completed the Supporting Tactical Athlete Readiness (STAR) program, a …

Selecting Dwarf Tomato Cultivars For Space-Limited Systems: Tradeoffs In Size, Yield, And Fruit Quality, Abigail Lazier, Bruce Bugbee, Noah Langenfeld

Plants, Soils and Climate Student Research

Global food systems face increasing pressure to produce more food with fewer resources, while urbanization limits access to traditional growing spaces. Urban agriculture offers a strategy to improve local food production, but space constraints remain a major challenge. Dwarf crops, bred to be compact and high yielding, can improve production efficiency in these systems. This study evaluated the growth habit, yield, and fruit quality of 18 dwarf tomato (Solanum lycopersicum) cultivars grown in controlled environment rooms under LED lights. Cultivars differed substantially in growth habit, size, yield and fruit quality. Generally, larger cultivars produced higher per-plant yields but …

Amyotrophic Lateral Sclerosis Risk Perceptions And Patient Burden, John William Glisson

Doctoral Dissertations and Projects

This quantitative, non-experimental, cross-sectional correlational study examined relationships among perceived environmental risk factors, depressive symptoms, and functional symptom burden in adults diagnosed with Amyotrophic Lateral Sclerosis (ALS). ALS is a progressive neurodegenerative condition with an unclear etiology, and some individuals attribute the diagnosis to environmental exposures such as pesticides or military service. The purpose of this study was to assess whether environmental risk perceptions were associated with depressive symptoms or functional impairment, and whether depressive symptoms were associated with functional status. Participants were recruited through online ALS support networks and advocacy organizations, resulting in a final sample of 145 adults …

25 Rules Of Thumb For Field Crops, Matt Yost, Niel Allen, Grant Cardon, Earl Creech, Ryan Larsen, Rhonda Miller, Mark Nelson, Claudia Nischwitz, Matthew Palmer, Steven Price, Ricardo Ramirez, Corey Ransom, Benjamin Scow, Randall Violett

All Current Publications

This article is not a comprehensive list of the practices farmers need to be successful in their operations, but it represents an attempt to capture 25 common tips or “rules” from a wide range of Extension experts throughout Utah, from seedbed preparation, to harvesting guidelines.

On-Farm Research Guide, Matt Yost, Jody Gale, Earl Creech, Megan Baker, Jeffrey Austin, Grant Cardon, Cody Zesiger

All Current Publications

Many growers want to increase crop productivity and farm profitability. On-farm research is a way growers can achieve this goal by discovering answers to important questions about the benefits of using specific products or practices they are uncertain about or are unproven. Validating the efficacy of already-implemented practices is another important reason to do on-farm research trials (Nielsen, 2008). Each farm is unique and can benefit from individualized on-farm research, especially since university and industry researchers cannot study every product or practice for every unique field or farm growing condition. This how-to guide covers benefits and best practices for conducting …

Irrigation Water Loss And Recovery In Utah, Bradley S. Crookston, Troy Peters, Matt Yost, Burdette Barker

All Current Publications

When deciding which irrigation systems to adopt, permit, or promote, it is important to consider how their efficiency and losses affect the water balance of Utah’s watersheds and drainage basins. Irrigators have no control over precipitation and only limited control of surface waters entering and leaving the state, as most of those are controlled by legal agreements. However, Utah’s water managers, elected officials, and water users can consider how surface water flows and groundwater storage is affected by using more efficient irrigation systems. Sprinkler, surface, or drip irrigation systems each have trade-offs in irrigation application efficiency, cost, and other factors. …

Guide To Drought Tolerance Of Utah Field Crops, Matt Yost, Tina Sullivan, Dakota Boren, Luree Johnson, Melanie Mills, Earl Creech, Boyd Kitchen, Randall Violett

All Current Publications

Crop variety selection is one of the most important choices on the farm. Crop genetics determine a significant portion of the yield potential and resource use efficiency. Crop types and genetics that use water more efficiently will become increasingly important as water becomes scarcer. Throughout Utah and the Western United States, water availability is decreasing due to various factors, including reduced snowpack and rapid urban growth. Alfalfa, other hay, small grains, and corn are grown on more acres than any other crops in Utah and much of the Intermountain West. These crops all have varieties, hybrids, and cultivars with the …

Transcriptomic Analysis Of Xeroderma Pigmentosum Group C Skin Samples, Austen N. Gleave

Theses and Dissertations

Xeroderma Pigmentosum is a rare genetic disorder caused by defective DNA damage repair enzymes. This condition results in an increased risk of developing skin cancer and other symptoms in those affected. In this thesis, we examined the effects of Xeroderma Pigmentosum on gene expression in patient skin biopsy samples. To accomplish this, we utilized statistical analysis of spatial transcriptomic and single-cell RNA sequencing techniques to discover differences between patient and heterozygous carrier skin samples. We found that the skin samples from Xeroderma Pigmentosum patients showed elevated levels of inflammation, immune activation, and cellular stress, while the carrier skin samples leaned …

Small Grain Forage Production Guide, Matt Yost, Megan Baker, Earl Creech, Justin Wyatt Clawson, Michael Pace, Kalen Taylor, Cory Farnsworth, Jacob Hadfield, Corey Ransom, Steven Price, Claudia Nischwitz, Clara Anderson

All Current Publications

Small grain forages can be used for pasture, hay, and silage and have become more common in cropping systems in Utah and the western United States. The most common small grain species used for forage production are barley, oat, rye, triticale, and wheat. Although there has been an increase in the use of small grains for forage production in the western U.S., little published information is available on best management practices for small grain forage production. This guide will discuss the key production practices for small grains used for forage.

Irrigation, Crop, And Soil Management Impacts On Water Use In Pivots/Laterals, Tejinder Singh, Matt Yost, Masoumeh Hashemi, Burdette Barker, Cheyenne Reid, Rebekah E. Iverson

All Current Publications

In this fact sheet, we describe evapotranspiration (ET), introduce a new tool, the soil moisture evapotranspiration (SMET) model, and share results from multi-year trials across Utah evaluating different center-pivot irrigation technologies, deficit irrigation strategies, crop types, drought-tolerant crop genetics, and conservation agriculture practices. These findings highlight how Utah growers can improve water productivity and maintain profitable production under limited water supplies.

Sorghum-Sudangrass Production Guide, Dakota Boren, Matt Yost, Luree Johnson, Tina Sullivan, Earl Creech, Grant Cardon, Corey Ransom, Randall Violett, Cheyenne Reid, Cody Zesiger, Kalen Taylor, Jacob Hadfield, Michael Pace, Jody Gale

All Current Publications

Sudex is a warm-season forage crop that performs well in Utah’s dry climate due to its drought tolerance. It can be especially useful during drought years or when irrigation supplies are limited. As well as being a high-quality feed, Sudex has many benefits, including weed suppression and soil-building properties. Although there are concerns for prussic acid and nitrate poisoning, these concerns can be reduced and often eliminated with proper management. This fact sheet provides information to producers about using Sudex and best production practices. Much of the information may also apply to forage sorghum and a few of the major …

Oxygen Under Pressure: A Comparative Study Of Maximal Oxygen Uptake In Firefighters And Civilians, Jordan N. Hunt

Doctoral Dissertations and Projects

The purpose of this study aimed to investigate and compare V̇O2max levels between firefighters and age-matched individuals from the general population. This study used a quantitative, comparative, cross-sectional design to assess differences in directly measured V̇O2max with a breath-by-breath portable analyzer between firefighters and matched civilians, determine the percentage of firefighters meeting NFPA recommended fitness thresholds, and examine the accuracy of estimated V̇O2max values. A total sample size of 52 participants (26 per group) participated in this study. Firefighters exhibited significantly higher directly measured V̇O2max and V̇O2peak than age-, sex-, and BMI-matched individuals from the general population. Firefighters in this …

The Effect Of Livelihood Capital Accessibility On The Financial Security And Financial Well-Being Of Sheep Farming Households (Survey In Wanaraja Subdistrict, Garut Regency), Suhendarsyah Suhendarsyah, Unang Yunasaf, Sondi Kuswaryan

Jurnal Ilmu Ternak Universitas Padjadjaran

This study analyzed the influence of livelihood capital accessibility on the financial security and financial well-being of sheep-farming households in Wanaraja Subdistrict, Garut Regency. A quantitative approach was used through a survey with organized interviews of 95 sheep farmers. The research variables include livelihood capital accessibility (X), financial security (Z), and financial well-being (Y). The livelihood capital accessibility construct was built as a Higher-Order Construct with five dimensions: human, natural, financial and physical capital. Data analysis used Partial Least Square Structural Equation Modeling (PLS_SEM) with a two-stage approach. The results evince that social capital are the most influential dimensions in …

Polymorphism Of The Mx Gene In Riau Kampung Chickens, Elfawati Elfawati, Restu Misrianti, Sadarman Sadarman

Jurnal Ilmu Ternak Universitas Padjadjaran

One of the genetic markers for avian influenza is the Mx gene. The purposed of this study was to determine the polymorphism of the Mx gene of kampung chicken in Riau Province. A total of 61 samples from three subpopulations have been genotyped using PCR-RFLP. Allele and genotype frequencies have been calculated using PopGene. The Mx gene was amplified, producing a DNA fragment measuring 299 base pairs. This fragment was digested with the Hpy81 enzyme, which yielded three genotypes: the AA genotype showed by a single 299 bp band; AG showed by 299, 200, and 99 bp bands; and GG …

Intersecting Determinants Of Health: Correlating Food Insecurity And Sleep Deprivation Across Southern Adventist University Demographics*, Heaven Robles, Jesica Paralafox Ramirez, Kimberly Mongare, Joshua C. Jenkins, Melany Castillo, Philip Chen Dr, Aaron Corbit Dr

Campus Research Month

For university students, social determinants of health such as food security and sleep patterns heavily dictate both health outcomes and academic success. Using a cross-sectional study design, statistical analyses will be conducted using the Jamovi software platform to compare mean sleep durations and food access scores across multiple academic departments and ethnic demographic groups. The study evaluates four primary hypotheses: (1) Consistent food access positively correlates with sleep quality; (2) Food security and sleep metrics vary significantly across academic departments; (3) Systemic ethnic disparities exist in food accessibility; and (4) Underrepresented ethnic groups experience a compounded burden of food insecurity …

Not Just Static: Evolutionary Throughlines In The Female Voice, Maria Hand '26

Honor Scholar Theses

Vocal communication is essential for many forms of human interaction and discourse. As such, the human voice has been the subject of extensive scientific research in a variety of contexts, including that of potentially evolved characteristics. Researchers have long studied the various changes that occur in direct relation to hormonal shifts across the ovulatory cycle, but one particularly interesting facet of this research is the voice. There are numerous acoustic parameters that are highly socially salient, and thus an ideal means with which to study potential ovulatory cycle related changes. Studies of this subject additionally provide further insight into the …

Psychosocial Mediators Of A Physical Activity And Dietary Intervention In Pregnant Women With Overweight Or Obesity, Meghan Baruth, Sarah Wilcox, Jihong Liu, Rebecca Schlaff

Faculty Publications

Background

Mediation analyses provide insight into both ‘pieces’ of the mediation chain; they allow us to look into the ‘black box’ that is behavior change. They allow researchers to better understand the ‘how’ of an intervention’s effects and/or the ‘why’ behind why an intervention worked or did not work. The lack of publications in pregnant populations highlights the need for additional studies to be conducted and published. The purpose of this study is to examine the psychosocial mediators of physical activity and dietary outcomes in a sample of pregnant women with overweight or obesity participating in the Health in Pregnancy …

Una To Put Names On 2 Buildings, Jennifer Edwards

Documents

the naming of the Academic Commons Building and the new Science and Technology Building at UNA

The Science And Technology Building University Of North Alabama, Barbie Hampel-University Advancement

Documents

Brochure and floor plans for the New Science and Technology Building at UNA

University Of North Alabama Science And Technology Building Grand Opening And Ribbon Cutting, University Of North Alabama

Documents

Invitation to the Grand Opening and Ribbon Cutting for the new Science and Technology Building at UNA