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Articles 1561 - 1590 of 40126
Full-Text Articles in Entire DC Network
Adopting Stuart Hall’S “Race, The Floating Signifier” As A Conceptual Framework Within Aquatic Research And Education, Kurt J. Cordice
Adopting Stuart Hall’S “Race, The Floating Signifier” As A Conceptual Framework Within Aquatic Research And Education, Kurt J. Cordice
International Journal of Aquatic Research and Education
During his 1997 lecture at Goldsmiths College in London, Stuart Hall, renowned for his contributions to sociology and cultural studies, offered his argument that the concept of race functions as a Floating Signifier. In this essay, Stuart Hall’s Race, the Floating Signifier is presented as a strong conceptual framework to support more accurate and effective positioning of race as an important consideration within aquatic research and education. Evidence from a range of disciplines, including historical research, is presented to establish both the importance and challenge of race within aquatic research and education. This evidence is also used to demonstrate …
An Innovative Approach Addressing Childhood Drowning: Making Use Of Collegiate Aquatic Facilities And Expertise, Gennette Cordova, Natasha Lloyd, Chezik Tsunoda
An Innovative Approach Addressing Childhood Drowning: Making Use Of Collegiate Aquatic Facilities And Expertise, Gennette Cordova, Natasha Lloyd, Chezik Tsunoda
International Journal of Aquatic Research and Education
The silent epidemic of childhood drowning, and the racial disparities associated with it require scalable and innovative approaches that both break cycles of exclusion and circumvent our societal tendency to overlook drowning as a matter in need of urgent resolution. No More Under, a Seattle-based water safety organization whose mission is to eradicate childhood drowning, has launched the Swim Safely Series. The series is a national program uniquely poised to overcome the various barriers associated with racial and socioeconomic drowning disparities by tapping into underutilized collegiate aquatic spaces and merging water safety with mentorship and social intervention.
Decadal Changes In Ground-Layer Plant Communities Reflect Maple Dieback And Earthworm Invasion In National Forests In The Lake Superior Region, Usa, Tara Bal, Manuel Eduardo Anderson, Mattison E. Brady, Julia I. Burton, Christopher R. Webster
Decadal Changes In Ground-Layer Plant Communities Reflect Maple Dieback And Earthworm Invasion In National Forests In The Lake Superior Region, Usa, Tara Bal, Manuel Eduardo Anderson, Mattison E. Brady, Julia I. Burton, Christopher R. Webster
Michigan Tech Publications
Northern hardwood forests of the Lake Superior region face a series of novel disturbance pressures including canopy dieback. Previous studies have linked regional sugar-maple (Acer saccharum) canopy dieback to introduced earthworms, which may have coinciding impacts on the ground-layer plant community. Dieback–earthworm interactions may lead to important longer-term changes in forest structure and function, but these relationships but have not been characterized. We sampled ground-layer plant communities in five national forest units in Michigan, Wisconsin, and Minnesota in 2010, and again just over a decade later in 2021. Non-metric multidimensional scaling ordination and indicator species analysis were used to assess …
Tng260 Is A Small-Molecule Corest Inhibitor That Sensitizes Stk11-Mutant Tumors To Anti-Pd-1 Immunotherapy, Leanne G Ahronian, Soumyadip Sahu, Minjie Zhang, Ayushi S Patel, Ke Geng, Reshmee Bhattacharya, Gerald S Falchook, Jonathan W Goldman, Alexander I Spira, Salman R Punekar, David R Spigel, Judy S Wang, Ferdinandos Skoulidis, Janaye Stephens, Mary Meynardie, Jaylen M Powell, Alfonso Lopez, Michela Ranieri, Magdalena A Ploszaj, Yi Jer Tan, Yeuan Ting Lee, Yi Yu, Jiehui Deng, Ting Chen, Patrick Mccarren, Alice Tsai, Suleman S Hussain, Brian Doyon, Kenjie Amemiya, Jacques Ermolieff, Preksha Shahagadkar, Nikitha M Das, Lauren R Flynn, Julie A Shields, Laney Danielczyk, Brian J Mcmillan, Andre Mignault, Samuel R Meier, Hsin-Jung Wu, David J Guerin, Douglas A Whittington, Chengyin Min, Iga Sienczylo, John P Maxwell, Heather J Dibenedetto, Hideo Watanabe, Brian B Haines, Alan Huang, Adam Crystal, Jannik N Andersen, Xinyuan Wu, Kwok-Kin Wong
Tng260 Is A Small-Molecule Corest Inhibitor That Sensitizes Stk11-Mutant Tumors To Anti-Pd-1 Immunotherapy, Leanne G Ahronian, Soumyadip Sahu, Minjie Zhang, Ayushi S Patel, Ke Geng, Reshmee Bhattacharya, Gerald S Falchook, Jonathan W Goldman, Alexander I Spira, Salman R Punekar, David R Spigel, Judy S Wang, Ferdinandos Skoulidis, Janaye Stephens, Mary Meynardie, Jaylen M Powell, Alfonso Lopez, Michela Ranieri, Magdalena A Ploszaj, Yi Jer Tan, Yeuan Ting Lee, Yi Yu, Jiehui Deng, Ting Chen, Patrick Mccarren, Alice Tsai, Suleman S Hussain, Brian Doyon, Kenjie Amemiya, Jacques Ermolieff, Preksha Shahagadkar, Nikitha M Das, Lauren R Flynn, Julie A Shields, Laney Danielczyk, Brian J Mcmillan, Andre Mignault, Samuel R Meier, Hsin-Jung Wu, David J Guerin, Douglas A Whittington, Chengyin Min, Iga Sienczylo, John P Maxwell, Heather J Dibenedetto, Hideo Watanabe, Brian B Haines, Alan Huang, Adam Crystal, Jannik N Andersen, Xinyuan Wu, Kwok-Kin Wong
Faculty, Staff and Student Publications
Patients with non–small cell lung cancer (NSCLC) with loss of the tumor suppressor gene STK11 are resistant to immune checkpoint therapies like anti–PD-1. In this study, we conducted an in vivo CRISPR screen that identified histone deacetylase 1 as a target to reverse anti–PD-1 resistance driven by loss of STK11 and developed TNG260, a potent small-molecule inhibitor of the CoREST complex with selectivity exceeding previously generated inhibitors in this class in preclinical studies. Treatment with TNG260 led to increased expression of immunomodulatory genes in STK11-deficient cancer cells. When combined with anti–PD-1, TNG260 induced immune-mediated stasis and/or regression in STK11 …
Understanding Callus Types In Maize By Genetic Mapping And Transcriptional Profiling, Guifang Lin, Yan Liu, Tej Man Tamang, Yang Qin, Mingxia Zhao, Hairong Wei, Et. Al.
Understanding Callus Types In Maize By Genetic Mapping And Transcriptional Profiling, Guifang Lin, Yan Liu, Tej Man Tamang, Yang Qin, Mingxia Zhao, Hairong Wei, Et. Al.
Michigan Tech Publications
Plant transformation efficiency is highly dependent on species, individual genotypes, and tissue types. In maize, immature embryos are regularly used for transformation. The process relies heavily on callus development, as it is intricately associated with somatic embryogenesis and subsequent plant regeneration, both of which directly affect transformation efficiency. Immature embryos of the segregation progeny derived from the two inbred parents, a transformation-amenable line A188 and a recalcitrant line B73, can be cultured to form two primary callus types: Type I and Type II. The Type II callus grows faster and is a favorable type for regeneration. Here, Type I and …
Resilience And Vulnerabilities Of Tumor Cells Under Purine Shortage Stress, Jianpeng Yu, Chen Jin, Cheng Su, David Moon, Michael A Sun, Hong Zhang, Xue Jiang, Fan Zhang, Nomi Tserentsoodol, Michelle L Bowie, Christopher J Pirozzi, Daniel J George, Robert Wild, Xia Gao, David M Ashley, Yiping He, Jiaoti Huang
Resilience And Vulnerabilities Of Tumor Cells Under Purine Shortage Stress, Jianpeng Yu, Chen Jin, Cheng Su, David Moon, Michael A Sun, Hong Zhang, Xue Jiang, Fan Zhang, Nomi Tserentsoodol, Michelle L Bowie, Christopher J Pirozzi, Daniel J George, Robert Wild, Xia Gao, David M Ashley, Yiping He, Jiaoti Huang
Faculty, Staff and Students Publications
Purpose: Purine metabolism is a promising therapeutic target in cancer; however, how cancer cells respond to purine shortage, particularly their adaptation and vulnerabilities, remains unclear.
Experimental design: Using the recently developed purine shortage-inducing prodrug DRP-104 and genetic approaches, we investigated the responses in prostate, lung, and glioma cancer models.
Results: We demonstrate that when de novo purine biosynthesis is compromised, cancer cells employ microtubules to assemble purinosomes, multiprotein complexes of de novo purine biosynthesis enzymes that enhance purine biosynthesis efficiency. Although this process enables tumor cells to adapt to purine shortage stress, it also renders them more susceptible to the …
Scalable Biosynthesis And Recovery Of Poly-3-Hydroxybutyrate Produced From Cotton-Derived Glucose By Cupriavidus Necator, Ashley M. Clark, Lucia E. Gargano, Gabriella M. Fioravanti, Hannah M. Schapiro, Ron G. Kander
Scalable Biosynthesis And Recovery Of Poly-3-Hydroxybutyrate Produced From Cotton-Derived Glucose By Cupriavidus Necator, Ashley M. Clark, Lucia E. Gargano, Gabriella M. Fioravanti, Hannah M. Schapiro, Ron G. Kander
School of Design and Engineering Papers
To combat the growing issue of petroleum plastic waste, alternative bio-based polymers are being developed. Many of these biopolymers are made from bio-derived materials, or are biodegradable, but the most promising polymers fall in both categories. Polyhydroxyalkanoates (PHAs) are one such class of polymers, and poly-3-hydroxybutyrate (P3HB), the most popular PHA, has shown great potential. This study utilized two types of cotton-derived glucose, alongside commercial glucose, as a feedstock for the biosynthesis of P3HB by Cupriavidus necator (also known as Ralstonia eutropha). The fermentation took place in a 2-L bioreactor, showing potential for scale-up. A single-solvent extraction method was …
Evaluation Of Anti-Bacterial Efficacy Of Ginger, Resin Gum, And Nigella Sativa Irrigants Against Enterococcus Faecalis: An In Vitro Study, Iman El Ghazzawy, Leen Imad Hasbini, Reem Chamseddine, Wael Betbout, Roula Abiad
Evaluation Of Anti-Bacterial Efficacy Of Ginger, Resin Gum, And Nigella Sativa Irrigants Against Enterococcus Faecalis: An In Vitro Study, Iman El Ghazzawy, Leen Imad Hasbini, Reem Chamseddine, Wael Betbout, Roula Abiad
International Arab Journal of Dentistry
Objectives: To evaluate the antibacterial efficacy of Ginger, Resin Gum, and Nigella Sativa, against Enterococcus Faecalis.
Methods: Thirty-eight extracted single-rooted premolars were inoculated with E.faecalis, except the negative control, and incubated for 4 weeks. After instrumentation samples were divided into 4 groups (n=7) according to final irrigation: NaOCl+EDTA (Group A), Nigella sativa (B), Resin Gum (C), Ginger (D), plus 2 control groups (n=5): Saline (E), and Saline without bacterial inoculation (F). Cultures were collected at baseline and after irrigation.
Results: One-way ANOVA showed that in groups A-D a statistically significant reduction of bacterial load was observed at …
An Examination Of The Experiences Of An African American Male Diver On A Power Four Swim Team: An Elite Interview, Steven N. Waller Ph.D., Tiffany M. Quash Ph.D.
An Examination Of The Experiences Of An African American Male Diver On A Power Four Swim Team: An Elite Interview, Steven N. Waller Ph.D., Tiffany M. Quash Ph.D.
International Journal of Aquatic Research and Education
Despite the incremental increase in the number of Black people who are learning to swim, the number of Black divers has not kept pace. In the NCAA Database, swimmers and divers were not segmented; thus, they all appear in the category of “swimming” by race and sex. When viewing the 2024 Division I NCAA Demographics Database, 89 (.02%) of 4307 student-athletes participating in swimming were Black women. For men, the data is equally dismal, revealing that 81 (.03%) of 2,608 student-athletes who were identified as swimmers were Black. The purpose of this research note is to examine the developmental experiences …
Quantifying Interest In And Sentiment Of Online Media About Greenhouse Gas Emissions From Cattle Production In The United States, Michael L. Smith, Jinho Jung, Nicole Olynk Widmar, Danielle J. Ufer, Maria Berikou, Jayson Lusk
Quantifying Interest In And Sentiment Of Online Media About Greenhouse Gas Emissions From Cattle Production In The United States, Michael L. Smith, Jinho Jung, Nicole Olynk Widmar, Danielle J. Ufer, Maria Berikou, Jayson Lusk
Department of Agricultural Economics Faculty Publications
The public is paying increased attention to the environmental impacts associated with cattle production systems in the US. Thus, cattle producers are increasingly exploring ways to communicate their efforts to reduce those environmental and climate impacts. This study uses online and social media data from 2018 to 2022 to examine public interest in and sentiment about beef and dairy cattle production when discussed within the context of greenhouse gas (GHG) emissions. Variation in mentions and net sentiment over the reporting period is quantified and analyzed. Over the period of data collection, which was interrupted by the COVID-19 pandemic, we find …
Needs Analysis Of Interactive Learning Media For Teachingheat Transfer In Physics: Students’ And Teachers’Perspectives, Rizki Eka Shintya, Ika Mustika Sari, Ida Kaniawati
Needs Analysis Of Interactive Learning Media For Teachingheat Transfer In Physics: Students’ And Teachers’Perspectives, Rizki Eka Shintya, Ika Mustika Sari, Ida Kaniawati
Jurnal Pendidikan Sains
Heat transfer material in physics is known to be abstract. This study specifically analyzes the conceptual difficulties, and visualization needs specific to this material, which is different from the analysis of physics needs in general. This analysis does not only look for the need for traditional media but explicitly looks for the need for interactive media (simulation, animation, virtual laboratory). Therefore, this study aims to identify the need for interactive learning media in physics education, specifically in the teaching of heat transfer, from the perspective of students and teachers in West Java, Indonesia. Using a quantitative descriptive survey, data were …
Efficacy Of Teaching At The Right Level Approach Combined With The Problem-Based Learning Model On Science Learning Outcomes At Middle School, Heri Syahputra Azhar Panjaitan, Ryan Dwi Puspita
Efficacy Of Teaching At The Right Level Approach Combined With The Problem-Based Learning Model On Science Learning Outcomes At Middle School, Heri Syahputra Azhar Panjaitan, Ryan Dwi Puspita
Jurnal Pendidikan Sains
This research seeks to evaluate the efficacy of the Teaching at the Right Level (TaRL) strategy in conjunction with the Problem-Based Learning (PBL) model on the scientific learning outcomes of eighth-grade students at middle school Islam Terpadu Khairul Imam. This research addresses the inadequate scientific problem-solving abilities and science learning outcomes of Indonesian students, necessitating a more interactive and individualized instructional technique. The methodology used is a quasi-experimental design with a nonequivalent control group. The sample included two purposively chosen eighth-grade classes: one experimental class (n=25) underwent the TaRL–PBL intervention, whereas the control class (n=25) simply used the lecture approach. …
Inhibition Of Osteosarcoma Lung Metastases By Β-Glucan And Cd40 Agonist Is Mediated By Activation Of Macrophages And Nk Cells, Pradeep Shrestha, Rejeena Shrestha, Eugenie S Kleinerman
Inhibition Of Osteosarcoma Lung Metastases By Β-Glucan And Cd40 Agonist Is Mediated By Activation Of Macrophages And Nk Cells, Pradeep Shrestha, Rejeena Shrestha, Eugenie S Kleinerman
Faculty, Staff and Student Publications
Background: Osteosarcoma (OS) lung metastases remain a significant therapeutic challenge. Innate immune activation is a promising therapeutic approach. Innate immune agonists can modulate the tumor immune microenvironment and improve therapeutic response.
Methods: Using an experimental syngeneic OS lung metastasis BALB/c mouse model with K7M3-luc OS cells, we evaluated the antitumor effects of yeast-derived particulate β-glucan in prevention and therapeutic settings. We then assessed whether the CD40 agonist (CD40a) in combination with β-glucan increased therapeutic response in two different immune-competent mouse models of OS lung tumor burden.
Results: In the pretreatment settings, mice treated with β-glucan prior to OS cell infusion …
Development Of Students Worksheet Based On Project-Based Learning To Train Critical Thinking Skills At Vocational High School, Dia Ayu Permatasari, Harun Nasruddin
Development Of Students Worksheet Based On Project-Based Learning To Train Critical Thinking Skills At Vocational High School, Dia Ayu Permatasari, Harun Nasruddin
Jurnal Pendidikan Sains
Critical thinking is a cognitive skill that helps identify problems and generate solutions, leading to logical decisions or considerations for solving those problems. Students' critical thinking skills can be trained through learning activities to further improve students' critical thinking skills with learning tools. Therefore, this research intends to produce a student worksheet based on project-based learning to train students' critical thinking skills on the colligative properties of solutions. The development research uses the 4D development model from Thiagarajan, limited to the development stage. A limited trial was conducted with 30 students of industrial chemical engineering expertise at Vocational High School …
Development Of Digital Comic Learning Media Based On Mobile Learning On Media: Making Media Materials In Plant Tissue Culture, Sufina Intan Pertiwi, Fauziyah Harahap, Aline Gusti Yolanda Harahap, Marsya Amira Indrawati, Aline Jelita Christiani Simanullang, Yanda Febry Gracea Br Tarigan, Maureen Efriyanti Sitinjak
Development Of Digital Comic Learning Media Based On Mobile Learning On Media: Making Media Materials In Plant Tissue Culture, Sufina Intan Pertiwi, Fauziyah Harahap, Aline Gusti Yolanda Harahap, Marsya Amira Indrawati, Aline Jelita Christiani Simanullang, Yanda Febry Gracea Br Tarigan, Maureen Efriyanti Sitinjak
Jurnal Pendidikan Sains
his research was conducted based on student needs analysis, analysis of learner characteristics, and curriculum analysis, namely the lack of visualization and presentation of concepts and the lack of utilization of interactive technology in the learning process on media material and media making in tissue culture for college students. This study intends to develop digital comic media based on mobile learning and making media materials in tissue culture. This research method used research and development (R&D) with the ADDIE model: analyze, design, develop, implement, and evaluate. The subjects of this study were students of the Department of Biology, Universitas Negeri …
Problem-Based Learning Assisted By Augmented Reality On The Respiratory System Topic: A Study Of Students’ Critical Thinking Skills And Learning Motivation, Nyimas Dilviana, Ade Yeti Nuryantini, Sumiyati Sa'adah
Problem-Based Learning Assisted By Augmented Reality On The Respiratory System Topic: A Study Of Students’ Critical Thinking Skills And Learning Motivation, Nyimas Dilviana, Ade Yeti Nuryantini, Sumiyati Sa'adah
Jurnal Pendidikan Sains
This study aims to examine the effectiveness of the Problem-Based Learning (PBL) model assisted by Augmented Reality (AR) technology regarding the respiratory system in improving students’ critical thinking skills and learning motivation. The research method used was a quasi-experimental design with a one-group pretest-posttest model. The subjects were 30 eleventh-grade students from a public high school in Garut City. Research instruments included a critical thinking test and a learning motivation questionnaire. The results showed a significant improvement in students’ critical thinking scores after the implementation of PBL with AR support. Additionally, learning motivation data analyzed from 16 statement items revealed …
Mechanistic Distinction Between Oxidative And Chlorination Transformations Of Chloroperoxidase From Caldariomyces Fumago Demonstrated By Dye Decolorization, Norman Paz-Ramirez, Jacob Redwinski, Matthew A. Cranswick, Kyle A. Grice, Kari Stone
Mechanistic Distinction Between Oxidative And Chlorination Transformations Of Chloroperoxidase From Caldariomyces Fumago Demonstrated By Dye Decolorization, Norman Paz-Ramirez, Jacob Redwinski, Matthew A. Cranswick, Kyle A. Grice, Kari Stone
Chemistry Department Faculty Articles
Effluents from the textile industry, particularly those containing synthetic azo dyes, poses a significant environmental threat, necessitating the development of more effective and sustainable pollutant removal methods. Traditional dye removal techniques often fall short in efficiency and environmental impact, prompting the exploration of enzymatic degradation as a promising alternative. This study focuses on chloroperoxidase, a natural biocatalyst recognized for its ability to oxidize synthetic dyes into less harmful products. By exploring the mechanistic distinction between chlorination and oxidative processes, we investigate the enzyme’s specific degradation pathways for azo dyes and the resulting by-products. Utilizing analytical techniques, including liquid chromatography/mass spectrometry …
Bacillus Sp. Sw14 Isolated From Arid Mangroves Sediments Enhances Tomato Plant Growth: Insights From Genome Analysis And Greenhouse Evaluation, Balamurugan Sadaiappan, Qurban Ali, Mahideen Afridi, Munawwar Ali Khan, Sunil Mundra
Bacillus Sp. Sw14 Isolated From Arid Mangroves Sediments Enhances Tomato Plant Growth: Insights From Genome Analysis And Greenhouse Evaluation, Balamurugan Sadaiappan, Qurban Ali, Mahideen Afridi, Munawwar Ali Khan, Sunil Mundra
All Works
Mangroves grow in arid regions with high temperatures, low precipitation, and evaporation. Despite low humidity and high salt concentration, these arid mangroves support diverse microorganisms, including salt-and temperature tolerant. The bacteria isolated from these arid mangroves have potential applications in arid agronomy, which alleviate plant stress and enhance plant growth. In this study, we characterize the genome of previously reported PGP and stress-tolerating bacteria, Bacillus sp. SW14, isolated from mangrove sediments of Umm Al Quwain, United Arab Emirates. Further, we investigated its effects on tomato seed germination and plant growth. Genome size of the strain SW14 is 4.25 MB, with …
Representation Is Power: Traditional, Hybrid, And Digital Recruitment Results From A Non-Randomized Clinical Trial Engaging Adolescents, Taylor B Harrison, Jessica A Sinclair, Lisa J Martin, Kristin Childers-Buschle, Holly Elder, Sunyang Fu, Hongfang Liu, William B Brinkman, Melanie F Myers, Michelle L Mcgowan
Representation Is Power: Traditional, Hybrid, And Digital Recruitment Results From A Non-Randomized Clinical Trial Engaging Adolescents, Taylor B Harrison, Jessica A Sinclair, Lisa J Martin, Kristin Childers-Buschle, Holly Elder, Sunyang Fu, Hongfang Liu, William B Brinkman, Melanie F Myers, Michelle L Mcgowan
Faculty, Staff and Student Publications
Clinical trials support the iterative advancement of modern medicine. However, challenges in achieving population-representativeness or participant sampling commensurate with the burden of disease can limit the generalizability and reproducibility of trial results. Here, we present the recruitment strategies and cohort profile of the Engaging Adolescents in Decisions about Return of Genomic Research Results non-randomized clinical trial (NCT0448106), where traditional, targeted hybrid, and digital recruitment methods were implemented with quota sampling to enroll diverse adolescents (ages 13-17) and young adults (ages 18-21). The largest proportion of participants enrolled through digital strategies (39.1%), followed by traditional (34.2%), and targeted hybrid strategies (23.2%). …
Assessing A Community Health Worker-Facilitated, Digitally Delivered, Family-Centered Diabetes Management Program: Single-Arm Quasi-Experimental Study, Zenong Yin, Vanessa L Errisuriz, Heather Cuevas, Bertha E Flores, Laura Delfausse, Christina Galvan, Jing Wang, Chengdong Li, Renata Morfin, Shiyu Li, Maysa Sapargeldiyeva, Giliane Yza Muyna, Minyu Zhang, Vanessa Sweet, Deborah Parra-Medina
Assessing A Community Health Worker-Facilitated, Digitally Delivered, Family-Centered Diabetes Management Program: Single-Arm Quasi-Experimental Study, Zenong Yin, Vanessa L Errisuriz, Heather Cuevas, Bertha E Flores, Laura Delfausse, Christina Galvan, Jing Wang, Chengdong Li, Renata Morfin, Shiyu Li, Maysa Sapargeldiyeva, Giliane Yza Muyna, Minyu Zhang, Vanessa Sweet, Deborah Parra-Medina
Faculty, Staff and Student Publications
Background: The high prevalence of type 2 diabetes (T2D) and associated complications disproportionately affect low-income Latino populations, who also experience disparities in diabetes self-management (DSM), including poor medication adherence, physical activity, diet, and glycemic control.
Objective: This study examined, through an academic-community partnership, the effectiveness of ¡Salud, Salud! (an evidence-based, family-centered diabetes self-management education and support [DSMES] program) on primary (glycemic control and quality of life) and secondary (social, psychological, and behavioral factors related to T2D management) outcomes among low-income Latino adults with T2D or prediabetes.
Methods: In total, 81 adults (mean age 48.90 years, SD 12.57; n=57, 70.4%, female; …
Atg16l1 Controls Mammalian Vacuolar Proton Atpase, Thabata L A Duque, Masroor Paddar, Einar Trosdal, Ruheena Javed, Lee Allers, Michal H Mudd, Prithvi Akepati, Soumya R Mishra, Michelle Salemi, Brett Phinney, Shawn B Bratton, Thomas Wileman, Vojo Deretic
Atg16l1 Controls Mammalian Vacuolar Proton Atpase, Thabata L A Duque, Masroor Paddar, Einar Trosdal, Ruheena Javed, Lee Allers, Michal H Mudd, Prithvi Akepati, Soumya R Mishra, Michelle Salemi, Brett Phinney, Shawn B Bratton, Thomas Wileman, Vojo Deretic
Faculty, Staff and Student Publications
The mechanisms governing mammalian proton pump V-ATPase function are of fundamental and medical interest. The assembly and disassembly of cytoplasmic V1 domain with the membrane-embedded V0 domain of V-ATPase is a key aspect of V-ATPase localization and function. Here, we show that the mammalian protein ATG16L1, primarily appreciated for its role in canonical autophagy and in noncanonical membrane atg8ylation processes, controls V-ATPase. ATG16L1 knockout elevated V-ATPase activity, increased V1 presence on endomembranes, and increased the number of acidified intracellular compartments. ATG16L1's ability to efficiently bind V-ATPase was required for its inhibitory role in endolysosomal acidification and for control of Mycobacterium …
Strain-Specific Variability In Viral Kinetics, Cytokine Response, And Cellular Damage In Air-Liquid Cultures Of Human Nasal Organoids After Infection With Sars-Cov-2, Gina M Aloisio, Trevor J Mcbride, Letisha Aideyan, Emily M Schultz, Ashley M Murray, Anubama Rajan, Erin G Nicholson, David Henke, Laura Ferlic-Stark, Amal Kambal, Hannah L Johnson, Elina A Mosa, Fabio Stossi, Sarah E Blutt, Pedro A Piedra, Vasanthi Avadhanula
Strain-Specific Variability In Viral Kinetics, Cytokine Response, And Cellular Damage In Air-Liquid Cultures Of Human Nasal Organoids After Infection With Sars-Cov-2, Gina M Aloisio, Trevor J Mcbride, Letisha Aideyan, Emily M Schultz, Ashley M Murray, Anubama Rajan, Erin G Nicholson, David Henke, Laura Ferlic-Stark, Amal Kambal, Hannah L Johnson, Elina A Mosa, Fabio Stossi, Sarah E Blutt, Pedro A Piedra, Vasanthi Avadhanula
Faculty, Staff and Students Publications
SARS-CoV-2 variants have demonstrated distinct epidemiological patterns and clinical presentations throughout the COVID-19 pandemic. Understanding variant-specific differences at the respiratory epithelium is crucial for understanding their pathogenesis. Here, we utilized human nasal organoid air-liquid interface (HNO-ALI) cell cultures to compare the viral replication kinetics, innate immune response, and epithelial damage of six different strains of SARS-CoV-2 (B.1.2, WA, Alpha, Beta, Delta, and Omicron). All variants replicated efficiently in HNO-ALIs, but with distinct replication kinetic patterns. The Delta variant exhibited delayed replication kinetics, achieving a steady state at 6 days post-infection compared to 3 days for other variants. Cytokine analysis revealed …
Factors Influencing Employee Green Behavior And Employee Green Attitude Among Muslims In Indonesia, Kurnia Sari Kasmiarno, Mahjus Ekananda, Gina Destrianti Karmanto
Factors Influencing Employee Green Behavior And Employee Green Attitude Among Muslims In Indonesia, Kurnia Sari Kasmiarno, Mahjus Ekananda, Gina Destrianti Karmanto
Journal of Environmental Science and Sustainable Development
In a Muslim majority, developing country like Indonesia, religion shapes employees’ work ethic and professional behavior, embedding spiritual and cultural values into the workplace. Despite the increasing attention to pro-environmental behavior, previous studies have largely examined Green Human Resource Management (GHRM), religiosity, and environmental concern separately, often focusing on a single sector. This leaves employees from various occupational backgrounds underexplored. This study aims to examine the effects of Green Concern (GC), Green Motivation (M), GHRM, and Religiosity (REL) on Employee Green Behavior (EGB) and Employee Green Attitude (EGA) of Muslim employees in Indonesia. Data were collected through a quantitative survey …
Implications Of Electric Vehicles Use On Value Co-Creation And Improving Community Welfare, Rastinia Kamila Hanum, Rizal Edy Halim
Implications Of Electric Vehicles Use On Value Co-Creation And Improving Community Welfare, Rastinia Kamila Hanum, Rizal Edy Halim
Journal of Environmental Science and Sustainable Development
Transportation is closely related and to support daily community mobility, 90% of road transportation operates on fossil fuel and it has always been accompanied by new innovations. Electric vehicles are predicted to be the future transportation to reduce greenhouse emissions. This study combines theories on behavioral and technology acceptance to create value co-creation and enhance community well-being. This quantitative study surveyed 210 respondents from the target community especially in Java island, who intend to adopt electric vehicles (EVs) using Google Form. PLS-SEM was used to evaluate research framework which integrates TPB, Technology Acceptance Model (TAM), and Unified Theory of Acceptance …
A Mast Cell Receptor Mediates Post-Stroke Brain Inflammation Via A Dural-Brain Axis, Ruchita Kothari, Mostafa W Abdulrahim, Hyun Jong Oh, Daniel H Capuzzi, Collin B Kilgore, Sumil K Nair, Yaowu Zhang, Nathachit Limjunyawong, Sarbjit S Saini, Jennifer E Kim, Justin M Caplan, Fernanado L Gonzalez, Christopher M Jackson, Chetan Bettegowda, Judy Huang, Bhanu P Ganesh, Chunfeng Tan, Raymond C Koehler, Rafael J Tamargo, Louise D Mccullough, Risheng Xu, Xinzhong Dong
A Mast Cell Receptor Mediates Post-Stroke Brain Inflammation Via A Dural-Brain Axis, Ruchita Kothari, Mostafa W Abdulrahim, Hyun Jong Oh, Daniel H Capuzzi, Collin B Kilgore, Sumil K Nair, Yaowu Zhang, Nathachit Limjunyawong, Sarbjit S Saini, Jennifer E Kim, Justin M Caplan, Fernanado L Gonzalez, Christopher M Jackson, Chetan Bettegowda, Judy Huang, Bhanu P Ganesh, Chunfeng Tan, Raymond C Koehler, Rafael J Tamargo, Louise D Mccullough, Risheng Xu, Xinzhong Dong
Faculty, Staff and Student Publications
The immune environment surrounding the brain plays a fundamental role in monitoring signs of injury. Insults, including ischemic stroke, can disrupt this balance and incite an exaggerated inflammatory response, yet the underlying mechanism remains unclear. Here, we show that the mast-cell-specific receptor Mrgprb2 regulates post-stroke brain inflammation from the meninges. Mrgprb2 causes meningeal mast cell degranulation after stroke, releasing immune mediators. This process recruits skull bone marrow neutrophils into the dura and further promotes neutrophil migration from the dura into the brain by cleaving the chemorepellent semaphorin 3a. We demonstrate that the human ortholog, MRGPRX2, is expressed in human meningeal …
Nebline, October 2025
NEBLINE Newsletter Archive from Nebraska Extension in Lancaster County
Contents
4-H super fair helps youth become beyond ready
What's popping? by Natalie Sehi
Recipes of the month, by Kayla Colgrove: Fish bait snack mix, kicked up popcorn, and cinnamon crunch snack mix
Are your trees for the next storm? by Rachel Anderson
Garden guide: Things to do this month by Mary Jane Frogge
GRO Big Red virtual learning series
Composting demonstration
Promoting language development in young children by Hayley Jackson
Tip sheet for harvest 2025 by John Nelson
Rogers Memorial Day farm field day, September 2025
Heart of 4-H volunteer award: Rachel Wells
Join 4-H to become beyond ready …
West Coast Demersal Scalefish Resource Recovery Support Package: 2024-25 Report, Department Of Primary Industries And Regional Development, Western Australia
West Coast Demersal Scalefish Resource Recovery Support Package: 2024-25 Report, Department Of Primary Industries And Regional Development, Western Australia
Fisheries Published Reports
The West Coast Demersal Scalefish Resource (WCDSR) includes over 100 species in inshore (20–250 m deep) and offshore ( > 250 m) demersal habitats of the West Coast Bioregion. These species are caught by charter, commercial and recreational fishers. The WCDSR is in recovery and managed under a 20-year recovery plan (2010–2030). DPIRD tracks recovery progress through scientific stock assessments of indicator species (snapper, WA dhufish, and baldchin groper) every 3 years. The 2021 WCDSR stock assessment showed limited recovery and additional management action was required. In December 2022, the Minister for Fisheries announced commercial and recreational (including charter) sector management …
Motives And Community Energy: What Determines Participation In The U.S. And E.U., Belinda Litchtenfeld
Motives And Community Energy: What Determines Participation In The U.S. And E.U., Belinda Litchtenfeld
Portugal: Sustainability and Environmental Justice
The shift to renewable energies has become a critical means of addressing the climate crisis. Community Energy (CE) has emerged as a ‘bottom-up’ transition to achieve decarbonization within a localized environment. The aim of this paper is to compare the motivations and framings of rural CE projects in the United States and European Union. The paper will compare the case of Loess Wind Farm, located in Rock Port, Missouri, with the Cedillo Solar Community in Caceres, Spain to determine how sociotechnical visions are shaped by the challenges facing communities. The elements of sociotechnical visions- meanings, knowings, doings, and organizings- as …
Creating Intergenerational Connections: A Multilevel Approach For Enriching Lives And Addressing Vital Community Issues, Matthew S. Kaplan, Nancy Z. Henkin
Creating Intergenerational Connections: A Multilevel Approach For Enriching Lives And Addressing Vital Community Issues, Matthew S. Kaplan, Nancy Z. Henkin
Journal of Human Sciences and Extension
This article presents an overview of intergenerational programs and practices as an interdisciplinary field of inquiry and practice that fosters open communication, support, and civic engagement across generations. Numerous examples of how intergenerational programs and practices harness age diversity to improve the human condition are presented. This includes initiatives to promote healthier lifestyles, reduce social isolation and loneliness, strengthen families, enrich education and lifelong learning, enhance community quality of life, and transmit cherished cultural traditions and values. This article highlights Extension’s longstanding contributions to intergenerational programming, showcasing notable examples across program areas and exploring opportunities for deeper engagement, co-leadership, and …
Intergenerational Creative Movement Program: A Social Connection Intervention To Foster Health And Well-Being, Claire M. Reardon, Mohammad Khalilian, Amy F. Kostelic, Susan Thiel, Anthony R. Bardo
Intergenerational Creative Movement Program: A Social Connection Intervention To Foster Health And Well-Being, Claire M. Reardon, Mohammad Khalilian, Amy F. Kostelic, Susan Thiel, Anthony R. Bardo
Journal of Human Sciences and Extension
A sense of connection and belonging is widely recognized to be essential for mental health. Yet, since the COVID-19 pandemic, loneliness, social isolation, and mental health problems have remained elevated across America. Transitions into young adulthood and older age, while distinct, similarly challenge social connectedness, especially among women. Our multi-lesson education program connected first-generation female college students with college-educated forty-plus women to foster belonging and improve mental health. The program integrated dance as a creative physical activity, promoted intergenerational engagement through a humanistic focus on generativity, and used a social network approach to gauge the development of connections among participants …