Open Access. Powered by Scholars. Published by Universities.®
- Institution
-
- University of Nebraska - Lincoln (4019)
- The Texas Medical Center Library (2199)
- Utah State University (2077)
- Brigham Young University (1610)
- University of Kentucky (1336)
-
- TÜBİTAK (1268)
- University of Arkansas, Fayetteville (1047)
- Wright State University (998)
- Louisiana State University (760)
- Old Dominion University (580)
- City University of New York (CUNY) (530)
- South Dakota State University (523)
- University of South Florida (471)
- Loyola University Chicago (422)
- Western Kentucky University (407)
- Virginia Commonwealth University (404)
- Department of Primary Industries and Regional Development, Western Australia (399)
- University of South Carolina (376)
- Technological University Dublin (366)
- California Polytechnic State University, San Luis Obispo (365)
- Universitas Indonesia (364)
- Clemson University (361)
- Wayne State University (329)
- Portland State University (328)
- Purdue University (323)
- Dartmouth College (322)
- University of Nevada, Las Vegas (316)
- University of Texas Rio Grande Valley (300)
- University of Central Florida (299)
- The University of Southern Mississippi (292)
- Keyword
-
- Humans (1392)
- Animals (918)
- Mice (715)
- Female (491)
- Male (353)
-
- Cancer (344)
- Tumor (286)
- Inflammation (273)
- Metabolism (267)
- Cell Line (260)
- Biology (259)
- Apoptosis (256)
- Cell Line, Tumor (255)
- Microbiology (251)
- Bacteria (249)
- Western Australia (240)
- Biological sciences (238)
- Genetics (235)
- COVID-19 (210)
- Nutrition (206)
- Agriculture (202)
- Mutation (202)
- Mitochondria (198)
- Breast cancer (184)
- Obesity (181)
- Climate change (169)
- RNA (167)
- Escherichia coli (155)
- Education (154)
- Sustainability (153)
- Publication Year
- Publication
-
- Theses and Dissertations (2409)
- Faculty, Staff and Student Publications (1357)
- Electronic Theses and Dissertations (876)
- Kno.e.sis Publications (540)
- All Graduate Theses and Dissertations, Spring 1920 to Summer 2023 (510)
-
- Graduate Theses and Dissertations (510)
- Master's Theses (476)
- Turkish Journal of Biology (448)
- Dissertations and Theses (Open Access) (416)
- Honors Theses (374)
- Faculty, Staff and Students Publications (346)
- Faculty Publications (336)
- Masters Theses (321)
- USF Tampa Graduate Theses and Dissertations (305)
- Dissertations (285)
- Dartmouth Scholarship (268)
- Turkish Journal of Agriculture and Forestry (266)
- Publications and Research (257)
- Scanning Microscopy (254)
- All Peer-Reviewed Publications (251)
- Articles (251)
- United States Department of Agriculture Wildlife Services: Staff Publications (250)
- Student Theses and Dissertations (249)
- Biology Faculty Publications (248)
- Browse all Theses and Dissertations (243)
- Turkish Journal of Veterinary & Animal Sciences (243)
- Department of Biochemistry: Faculty Publications (237)
- Jurnal Kultivasi (232)
- LSU Master's Theses (226)
- IGC Proceedings (1977-2023) (206)
- Publication Type
Articles 1291 - 1320 of 40122
Full-Text Articles in Entire DC Network
Promoting The Synthesis Of Salicylic Acid In Escherichia Coli Based On Metabolic Engineering And Multi-Enzyme Cascade Strategy, Kai Wang, Xuewei Pan, Taowei Yang, Zhiming Rao
Promoting The Synthesis Of Salicylic Acid In Escherichia Coli Based On Metabolic Engineering And Multi-Enzyme Cascade Strategy, Kai Wang, Xuewei Pan, Taowei Yang, Zhiming Rao
Journal of Food Science and Biotechnology
[Objective ] The production of the aromatic compound salicylic acid (SA) is limited by its inhibitory effects on enzymes related to cellular energy metabolism.This study aims to develop a strategy for avoiding the impact of SA on enzymes related to cellular energy metabolism and increase the yield of SA.[Method ] A highly efficient Escherichia coli strain was designed to improve SA production by optimizing metabolic pathways and enzyme systems.[Result ] The genome-scale metabolic model GEMS 1515 was employed to predict the key bottle necks in the phosphoenolpyruvic acid (PEP) pathway and SA biosynthesis pathways.The SA yield was successfully increased from …
Application Of A Rapid Test Strip Method In Quantitative Detection Of Microorganisms In Chilled Meat, Yanzhen Zhang, Ning Liu, Wei Wang, Xianqi Yao, Laixue Ni, Yunguo Liu
Application Of A Rapid Test Strip Method In Quantitative Detection Of Microorganisms In Chilled Meat, Yanzhen Zhang, Ning Liu, Wei Wang, Xianqi Yao, Laixue Ni, Yunguo Liu
Journal of Food Science and Biotechnology
[Objective ] This study aims to evaluate the feasibility of using the rapid test strip method for detecting key microbial quality control indicators in chilled meat,specifically the total plate count and Escherichia coli /coliforms.[Method ] The performance of the rapid test strip method was assessed through repeatability tests,and the national standard plate count method was used as the reference for method comparison.Statistical significance of the quantification results was analyzed by a t-test,and linear regression was adopted to analyze the correlation.[Result ] The repeatability deviation of the rapid test strip method (r≤0.25) met the requirements of ISO 4833—1:2013.No significant difference was …
Rab32c Mediates Osmoregulation And Calcium Homeoastasis In Dictyostelium Discoideum, Ashley Esparza
Rab32c Mediates Osmoregulation And Calcium Homeoastasis In Dictyostelium Discoideum, Ashley Esparza
Theses and Dissertations
Vesicular trafficking is a fundamental process essential to cell viability and dictates roles in both cellular and tissue function in multicellular organisms. To further understand various vesicular trafficking processes, our lab focuses on the moderators of these processes, Rab GTPases, using the model organism Dictyostelium discoideum. This dissertation focuses explicitly on the uncharacterized protein Rab32C, a homolog of human Rab32. While several Rab family members have been well defined, the functionality of Rab32C remains poorly understood. This project investigated both the subcellular localization and functional role of Rab32C with biochemical, imaging, and molecular assays. Results from this study provide evidence …
Plant Preservation: The Contribution Of Bacteriophage And Transposons To Pathogenic Xanthomonas Evolution, And The Demographic And Reproductive Analysis Of Castilleja Parvula, Ciara A. Green
Theses and Dissertations
Plant preservation, whether through disease research or endemic extinction analyses, plays an important role in the relationship between humans and our surrounding environment. In these analyses, both the role of mobile elements in the evolution of pathogenic Xanthomonas sp. bacteria, and the demographic and reproductive analysis of Castilleja parvula, an imperiled alpine plant, are evaluated. Xanthomonas species are one of the top agricultural threats, and are known to evolve rapidly. Until now, the contributions of mobile elements and particularly bacteriophage have not been thoroughly evaluated. The contribution of these agricultural diseases to food insecurity and the devastation of crops that …
Fabrication Of Three-Dimensional Seaweed-Based Scaffolds And Evaluation Of Cell Attachment And Viability For Cultured Meat Applications, Srishti Tandon
Fabrication Of Three-Dimensional Seaweed-Based Scaffolds And Evaluation Of Cell Attachment And Viability For Cultured Meat Applications, Srishti Tandon
Honors Scholar Theses
Global demand for animal protein is increasing rapidly, underscoring the need for sustainable meat production. Cultured meat is a promising alternative to traditional meat production techniques, but it requires optimization before it can be implemented on a large scale. Scaffolds are an important component for making cultured meat, as they provide structural support for cell attachment and mimic the texture of meat. Scaffolds need to be biocompatible, mechanically supportive, and biochemically active to promote proper cell adhesion, proliferation, and differentiation. This project investigated brown seaweed extract (SWE) hydrogels as a scaffold for cultivated meat applications and compared their mechanical and …
Investigation Of Mono-Allelic Rack1 Deletion Effects On Cell Growth And Pkc Mrna Expression, Ashen Quiambao
Investigation Of Mono-Allelic Rack1 Deletion Effects On Cell Growth And Pkc Mrna Expression, Ashen Quiambao
Seton Hall University Dissertations and Theses (ETDs)
The µ-opioid receptor is a primary target of clinically used opioids, and RACK1 regulates its transcription by physically interacting with MOR transcription regulator PCBP1 in the cytosol to prevent its nucleus translocation. Two mono-allelic RACK1 knockout cell lines named RACKA and RACKB were generated by the CRISPR-Cas9 technique using WT NMB neuroblastoma cells. As RACK1 also contains a PKC-binding domain, this study aims to evaluate the impacts of mono-allelic deletion on cell growth rates and PKC isoform expression. Although a slight decreased tendency of growth rate in RACKA and RACKB cells was observed when compared to that of WT NMB …
Role Of Recreational Fisher Information In Fisheries Management, Rebecca M. Krogman, Stephen M. Taylor, Aaron J. Adams, Ross E. Boucek, Steven M. Lombardo, Chelsey A. Crandall, Susan F. Steffen, Alejandro Acosta, Eduardo Bone Moron, Sepp Haukebo, Kieran Hyder, Zachary M. Radford, Warren M. Potts
Role Of Recreational Fisher Information In Fisheries Management, Rebecca M. Krogman, Stephen M. Taylor, Aaron J. Adams, Ross E. Boucek, Steven M. Lombardo, Chelsey A. Crandall, Susan F. Steffen, Alejandro Acosta, Eduardo Bone Moron, Sepp Haukebo, Kieran Hyder, Zachary M. Radford, Warren M. Potts
Books & book chapters
Fisheries managers work with the three components of fisheries—biota, environment, and people - to achieve recreational, stewardship, and socioeconomic goals. Although manipulation of biota and the aquatic environment remains popular (e.g. harvest regulation, protecting or enhancing habitats, and guarding water quality), the human dimension of fisheries must also be considered throughout the fisheries management process. Managers can and should engage fishers in a myriad of ways, from identification of problems to guidance on alternatives, and from measurement of change to evaluation of success. In this chapter, we review common fisheries management goals and objectives; detail information needs stemming from those …
Effects Of Supplemental Led Lighting And Biofertilizer On Yield And Fruit Quality Of Japanese Strawberry Cultivars In Indonesia, Reginawanti Hindersah, Febby Fitriyani, Kenji Endo, Masakazu Nakayama, Syariful Mubarok, Gita Bina Nugraha
Effects Of Supplemental Led Lighting And Biofertilizer On Yield And Fruit Quality Of Japanese Strawberry Cultivars In Indonesia, Reginawanti Hindersah, Febby Fitriyani, Kenji Endo, Masakazu Nakayama, Syariful Mubarok, Gita Bina Nugraha
Jurnal Kultivasi
Growing strawberries in soilless substrates in the greenhouse relies on fertilizers and supplemental light to boost yield and fruit quality. The research evaluated the properties of the biofertilizer and its effectiveness on the yield of Japanese strawberry cultivars Nanatsuboshi and KS-75 under controlled greenhouse conditions, with and without light-emitting diodes (LED) as supplemental light. The cell viability and plant-growth-promoting properties of a liquid consortium biofertilizer consisting of nitrogen-fixing bacteria and phosphate-solubilizing microbes, were characterized. Laboratory analysis confirmed the biofertilizer's composition, and a greenhouse experiment using a completely randomized design tested treatments of biofertilizer, LED, and their combination. The biofertilizer contained …
Neurobehavioral Mechanisms Of Psychotic-Like Experiences And Cannabis Use, Ethan Campbell
Neurobehavioral Mechanisms Of Psychotic-Like Experiences And Cannabis Use, Ethan Campbell
Psychology ETDs
As cannabis use has increased steadily over the past decade, there is critical need to evaluate early cannabis use as a potential risk factor for the development of psychosis. Neurobehavioral mechanisms underlying novelty salience could clarify how cannabis exposure may influence subclinical psychotic-like experiences (PLEs). The present study leveraged dynamic functional connectivity and task-fMRI to assess the role of novelty processing in cannabis use and PLEs. A group of brain regions dynamically tied to the salience network while viewing short films were found to increase their activation as a function of stimulus novelty during a novelty bandit task. PLEs were …
Efficacy Of Oil And Gas Production Site Remediation In U.S. Arid/Semi-Arid Regions, Skye Ontiveros
Efficacy Of Oil And Gas Production Site Remediation In U.S. Arid/Semi-Arid Regions, Skye Ontiveros
Architecture and Planning ETDs
Oil and gas production (OGP) is expanding, paralleled by its polluting leaks and spills (LS), and outpaced by its waste. This raises the question: Does remediation of LS occur effectively when needed to protect the environment and public, particularly in major producing regions like arid/semi-arid regions (ASAR), which account for approximately 72% of US oil and 42% of gas production? To answer, a review of the eight largest national remedial laws, sourced from the Code of Federal Regulations (CFR), identified 14 OGP exemptions for remedial determinants (RDs): factors affecting remedial frequency and efficacy (e.g. LS monitoring and chemical disclosure). An …
Listen To The Birds: Sound Ecology At The Piano, Anna Showalter
Listen To The Birds: Sound Ecology At The Piano, Anna Showalter
Dissertations, 2020-current
This document explores the intersection between birdsong and piano music using four cases studies from the piano repertoire in the Western classical tradition. Using Jeff Titon’s framework of “sound ecology” as a lens, I ask whether the following pieces of music could in some way function as an “acoustic tissue among human and bird communities that becomes the basis for a healthy economy and a just community.” After exploring the history of birdsong in the piano literature as a microcosm of shifting attitudes toward birdsong in Western art music this study focuses on four pieces as case studies for analysis—Amy …
Experimental Investigation On Thermal And Exergetic Performance Improvement Of A Half-Cylindrical Solar Still Using Pcm And Reflectors, Ahmed Saad Soliman, Ping Cheng, Ahmed A. Sultan, Osama Abdelrehim, Asmaa Khater, Mohamed A. Sultan
Experimental Investigation On Thermal And Exergetic Performance Improvement Of A Half-Cylindrical Solar Still Using Pcm And Reflectors, Ahmed Saad Soliman, Ping Cheng, Ahmed A. Sultan, Osama Abdelrehim, Asmaa Khater, Mohamed A. Sultan
Mansoura Engineering Journal
This study explores the potential of enhancing solar still performance by integrating a corrugated absorber with phase change material (PCM) and a reflector. The study aims to improve water yield, extend operation beyond sunset, and boost thermal and exergy efficiencies compared to a conventional flat absorber. Experiments were carried out on flat, corrugated, and corrugated-with-PCM absorbers, both with and without reflectors, to evaluate the effect of each modification. The results show that using a reflector with a flat absorber improved daily productivity by 22%. A corrugated absorber increased accumulated productivity by 38%, and when combined with a reflector, the improvement …
The Relationship Between Light Physical Activity And 10-Year Weight Change In 2,868 U.S. Adults: A National Health And Nutrition Examination Survey Investigation, Chloe Diane Cory
The Relationship Between Light Physical Activity And 10-Year Weight Change In 2,868 U.S. Adults: A National Health And Nutrition Examination Survey Investigation, Chloe Diane Cory
Theses and Dissertations
The prevalence of obesity has steadily increased over the past several decades. About 13.4% of Americans aged 20-74 had obesity in 1960-1962 and the prevalence has steadily increased to 40.3% in 2021-2023--more than a 3-fold increase. PURPOSE: The aim of this study was to evaluate the relationship between time spent in light physical activity (LPA) and 10-year weight change in a random sample of 2868 women and men representative of the U.S. adult population. METHODS: Data were used from the National Health and Nutrition Examination Survey (NHANES) from the 2003-2006 data cycles. Participants were limited to non-pregnant U.S. …
Aqueous Geochemistry Drives Microbial Cu, Fe, And Zn Uptake Rates In Yellowstone, A Continental Hydrothermal System, Eva Carolina Andrade-Barahona
Aqueous Geochemistry Drives Microbial Cu, Fe, And Zn Uptake Rates In Yellowstone, A Continental Hydrothermal System, Eva Carolina Andrade-Barahona
Graduate Theses & Non-Theses
Microbial uptake of trace metal cofactors such as copper (Cu), iron (Fe), and zinc (Zn) is governed by biogeochemical processes in hydrothermal systems where metal bioavailability varies widely. In situ microbial metal uptake rates were quantified by applying metal stable isotope probing (MSIP) in the Yellowstone hydrothermal system across diverse geochemical conditions in hydrothermal springs. The findings in these studies revealed that pH exerts a dominant influence on microbial copper uptake rate, also enhanced by increased Cu²⁺ ion availability and dissolved oxygen. Microbial iron uptake, in contrast, displayed a broad tolerance to environmental variability, occurring across a pH range of …
The Cytotoxicity And Anti-Inflammatory Properties Of 1’S-1’-Acetoxychavicol Acetate (Aca) On Oral Cells, Nur Umairah Atiqah Sabri, Nor Syazwani Muhammad Zahidan, Zulfahmi Said, Siti Noor Adnalizawati Adnan, Normaliza Ab Malik
The Cytotoxicity And Anti-Inflammatory Properties Of 1’S-1’-Acetoxychavicol Acetate (Aca) On Oral Cells, Nur Umairah Atiqah Sabri, Nor Syazwani Muhammad Zahidan, Zulfahmi Said, Siti Noor Adnalizawati Adnan, Normaliza Ab Malik
Journal of Dentistry Indonesia
Objective: Mouthwash is widely used to maintain oral health by reducing the prevalence of pathogenic microbiomes. Nonetheless, chlorhexidine, a common active ingredient, is associated with side effects including teeth staining, mucosal peeling, mouth and tongue numbness. This has prompted interest in natural alternatives. This study aimed to identify the cytotoxicity and anti-inflammatory properties of 1’S-1’-acetoxychavicol acetate (ACA) isolated from Alpinia conchigera rhizome against human primary gingival fibroblast and keratinocyte (HPGF and HPGK). Methods: Cytotoxicity of ACA (1.57 mg/mL) against HPGF and HPGK was assessed using the MTT assay. Meanwhile, the anti-inflammatory property of ACA was analyzed based on …
Growth Of Porang (Amorphopallus Muelleri) Seedlings As Influenced By Seed Maturity And The Presence Of Sarcotesta, Indri Fariroh, Restiani Sih Harsanti, Aminatun Nisa, Didik Pudji Restanto, Rizky Anugerah Putra
Growth Of Porang (Amorphopallus Muelleri) Seedlings As Influenced By Seed Maturity And The Presence Of Sarcotesta, Indri Fariroh, Restiani Sih Harsanti, Aminatun Nisa, Didik Pudji Restanto, Rizky Anugerah Putra
Jurnal Kultivasi
Porang seed maturity based its position on spadix position significantly impacts germination. The presence of the seed coat (sarcotesta) also influenced germination and initial seedling growth. This study aimed to explore the effect of seed maturity and the presence of sarcotesta to the seedling growth. The experiment was conducted from January to June 2023. A two factor Randomized Complete Block Design was employed, examining three maturity levels based on spadix position (physiological maturity seed from the tip spadix (red colour), half physiological maturity seed from the middle spadix (orange colour), and immature seed from the base spadix (green colour)), and …
Production Analysis Of Seed-Derived Tea Plants (Camellia Sinensis (L.) O. Kuntze) Across Two Different Seasons, Nurlita Rahmawati, Yudithia Maxiselly, Intan Ratna Dewi Anjarsari, Heri Syahrian Khomaeni, Gerry Renaldi, Agung Karuniawan
Production Analysis Of Seed-Derived Tea Plants (Camellia Sinensis (L.) O. Kuntze) Across Two Different Seasons, Nurlita Rahmawati, Yudithia Maxiselly, Intan Ratna Dewi Anjarsari, Heri Syahrian Khomaeni, Gerry Renaldi, Agung Karuniawan
Jurnal Kultivasi
Tea (Camellia sinensis (L.) O. Kuntze) is a major economic crop in Indonesia, yet its productivity is strongly influenced by environmental variability, particularly rainfall seasonality. Fluctuating yields under dry and wet conditions pose challenges for sustainable tea production. This study aimed to assess the effects of contrasting seasonal rainfall on seed-derived tea plants' yield and yield components. The research was conducted at a seed-derived tea plantation block in IRITC, West Java, across dry and wet seasons using field observations on tea yield, shoot proliferation, plucking quality, and environmental parameters. Statistical analyses included independent t-tests to compare seasonal differences and Pearson …
Study Of Insect Frass-Associated Microbiome On Plant Growth And Their Potential Use As Biofertilizer, Jasmine Sahota
Study Of Insect Frass-Associated Microbiome On Plant Growth And Their Potential Use As Biofertilizer, Jasmine Sahota
Theses and Dissertations
An increasing global food demand and the urgent need for sustainable agricultural practices have driven interest in insects as alternative feed and food sources. Insect frass, a by-product of insect rearing, represents a rich organic carbon source with diverse microbes that can enhance soil health and promote beneficial plant-microbe interactions. This study characterized the bacterial (16S-V4) and fungal (ITS2) microbiomes of frass from Black Soldier Fly (BSF) and Cricket species and evaluated their effects on maize (Zea mays) growth. Four frass variants were applied at rates of 56-280 kg ha⁻¹ in a pot experiment with untreated soil and mineral fertilizer …
Spatiotemporal Ecology Of Mycobacterium Ulcerans And Mycolactone Functions In French Guiana And Southeastern United States Aquatic Environments, Magdalene Dogbe
Spatiotemporal Ecology Of Mycobacterium Ulcerans And Mycolactone Functions In French Guiana And Southeastern United States Aquatic Environments, Magdalene Dogbe
Theses and Dissertations
Mycobacterium ulcerans, the causative agent of Buruli ulcer, produces mycolactone, a polyketide toxin traditionally studied for its role in human pathogenesis. This dissertation presents a comprehensive spatiotemporal analysis of M. ulcerans and mycolactone producing mycobacteria (MPM) ecology in the Americas and also reveals mycolactone's role in the environment as a microbial community regulator. Through comparative studies in French Guiana (endemic) and the southeastern United States (non-endemic), combined with experimental microcosm investigations, this research contributes to environmental pathogen ecology understanding. Environmental surveillance across 2,226 samples from French Guiana revealed complete MPM restriction to freshwater environments, with zero detections from 1,226 coastal …
How The Intake Of Pulses May Impact Metabolic Disorders And Dementia Risk: A Narrative Review, Lisa Michelle Belzer Salinas, Maricarmen Marroquin, Mariana Mendez, Isabel Omaña-Guzmán, Juan Carlos López-Alvarenga
How The Intake Of Pulses May Impact Metabolic Disorders And Dementia Risk: A Narrative Review, Lisa Michelle Belzer Salinas, Maricarmen Marroquin, Mariana Mendez, Isabel Omaña-Guzmán, Juan Carlos López-Alvarenga
Health & Biomedical Sciences Faculty Publications
We present a narrative review focusing on pulses’ geographical origin and distribution, their impact on human evolution and history, and their influence on human health. Pulses, including dry peas, beans, and lentils, are renowned for their richness in chemical antioxidants. Despite containing antinutrients, processing techniques preserve their health advantages. Epidemiological research has consistently demonstrated that the consumption of pulses is associated with favorable effects on metabolism. This evidence is further supported by molecular and clinical research, which has elucidated potential nutrigenomic mechanisms and effects on gut microbiota composition underlying their health benefits. However, the literature lacks randomized controlled clinical trials …
Understanding Outer Membrane Vesicle Biogenesis In Bacteroides Thetaiotaomicron, Evan J. Pardue
Understanding Outer Membrane Vesicle Biogenesis In Bacteroides Thetaiotaomicron, Evan J. Pardue
Arts & Sciences Graduate Student Theses and Dissertations
Outer membrane vesicles (OMVs) are small proteoliposomes generated by active protrusion of the outer membrane (OM) in Gram-negative bacteria during growth. Over 60 years of experimentation has ascribed numerous functions to OMVs produced by different bacteria. However, the mechanism(s) by which OMVs are produced is poorly understood. Due to this, the field remains controversial because many regard OMVs as byproducts of cell lysis and question their physiological relevance. Previous studies in Pseudomonas aeruginosa and related species confirmed that these microbes undergo programmed cell death that results in the stochastic release of vesicles and cellular contents. On the contrary, Bacteroides spp. …
Reducing Foodborne Bacteria Public Health Burden By Novel Compounds And Pressure-Based Technologies, Junice Alannah Sibley
Reducing Foodborne Bacteria Public Health Burden By Novel Compounds And Pressure-Based Technologies, Junice Alannah Sibley
Tennessee State University Alumni Theses and Dissertations
Food safety strategies are being developed in the hopes of combating foodborne pathogens and their risks. Previous techniques and technologies are struggling to meet the needs of the public, leading to the demand for new, innovative methods. Mild high-pressure processing (HPP) of 350 MPa was used in a synergetic combination with mild heat of 60°C and the antimicrobial carvacrol for the decontamination of non-typhoidal Salmonella serovars that resulted in a >5 log CFU/mL reduction. Additionally, a secondary study was conducted comparing a single Salmonella Tennessee strain with a 4-strain Salmonella cocktail to examine sensitivity to pressure-based treatments resulting in a …
The Role Of Toll-Like Receptors In Tributyltin, Dibutyltin, And Pentachlorophenol Stimulation Of Tumor Necrosis Factor Alpha Production By Human Immune Cells, Latoya Michelle Daniel
The Role Of Toll-Like Receptors In Tributyltin, Dibutyltin, And Pentachlorophenol Stimulation Of Tumor Necrosis Factor Alpha Production By Human Immune Cells, Latoya Michelle Daniel
Tennessee State University Alumni Theses and Dissertations
Tributyltin (TBT), Dibutyltin (DBT), and Pentachlorophenol (PCP) are persistent environmental contaminants that have been shown to increase immune-cell production of pro-inflammatory cytokines and thus have the capacity to cause chronic inflammation and its associated pathologies such as cancer, cardiovascular disorders, and autoimmune conditions. TBT has been detected in human blood at concentrations up to 260 nM, DBT up to 0.3 µM, and PCP between 0.15 and 5 µM. Tumor necrosis factor-alpha (TNF-α) is a pro-inflammatory cytokine produced by immune cells in response to pathogen- or damage-associated molecular patterns (PAMPs/DAMPs) via Toll-like receptors (TLRs). Dysregulated TNF-α production contributes to chronic inflammatory …
Tennessee’S Green Industry: An Economic Impact Assessment, Savannah R. Lewis
Tennessee’S Green Industry: An Economic Impact Assessment, Savannah R. Lewis
Tennessee State University Alumni Theses and Dissertations
This study estimates the economic contributions of the greenhouse and nursery industry, commonly known as the "green industry," in Tennessee for 2023. Utilizing data on employment, labor income, value added, and industry output, alongside economic multipliers generated from the Input-Output modeling software, IMPLAN (Impact Analysis for Planning), we provide a comprehensive analysis of the green industry's impact on the state's agricultural economy. The findings are presented in 2025 dollars, highlighting the industry's significance for informing future policy decisions. The primary objectives were to assess total contributions at the state, regional, and county levels. Direct employment across all sectors was estimated …
Genetic Modifiers And Ascertainment Drive Variable Expressivity Of Complex Disorders, Matthew Jensen, Corrine Smolen, Anastasia Tyryshkina, Lucilla Pizzo, Jiawan Sun, Serena Noss, Deepro Banerjee, Matthew Oetjens, Hermela Shimelis, Cora M Taylor, Vijay Kumar Pounraja, Hyebin Song, Laura Rohan, Emily Huber, Laila El Khattabi, Ingrid Van De Laar, Rafik Tadros, Connie R Bezzina, Marjon Van Slegtenhorst, Janneke Kammeraad, Paolo Prontera, Jean-Hubert Caberg, Harry Fraser, Siddharth Banka, Anke Van Dijck, Charles Schwartz, Els Voorhoeve, Patrick Callier, Anne-Laure Mosca-Boidron, Nathalie Marle, Mathilde Lefebvre, Kate Pope, Penny Snell, Amber Boys, Paul J Lockhart, Myla Ashfaq, Elizabeth Mccready, Margaret Nowacyzk, Lucia Castiglia, Ornella Galesi, Emanuela Avola, Teresa Mattina, Marco Fichera, Maria Grazia Bruccheri, Giuseppa Maria Luana Mandarà, Francesca Mari, Flavia Privitera, Ilaria Longo, Aurora Curró, Alessandra Renieri, Boris Keren, Perrine Charles, Silvestre Cuinat, Mathilde Nizon, Olivier Pichon, Claire Bénéteau, Radka Stoeva, Dominique Martin-Coignard, Sophia Blesson, Cedric Le Caignec, Sandra Mercier, Marie Vincent, Christa L Martin, Katrin Mannik, Alexandre Reymond, Laurence Faivre, Erik Sistermans, R Frank Kooy, David J Amor, Corrado Romano, Joris Andrieux, Santhosh Girirajan
Genetic Modifiers And Ascertainment Drive Variable Expressivity Of Complex Disorders, Matthew Jensen, Corrine Smolen, Anastasia Tyryshkina, Lucilla Pizzo, Jiawan Sun, Serena Noss, Deepro Banerjee, Matthew Oetjens, Hermela Shimelis, Cora M Taylor, Vijay Kumar Pounraja, Hyebin Song, Laura Rohan, Emily Huber, Laila El Khattabi, Ingrid Van De Laar, Rafik Tadros, Connie R Bezzina, Marjon Van Slegtenhorst, Janneke Kammeraad, Paolo Prontera, Jean-Hubert Caberg, Harry Fraser, Siddharth Banka, Anke Van Dijck, Charles Schwartz, Els Voorhoeve, Patrick Callier, Anne-Laure Mosca-Boidron, Nathalie Marle, Mathilde Lefebvre, Kate Pope, Penny Snell, Amber Boys, Paul J Lockhart, Myla Ashfaq, Elizabeth Mccready, Margaret Nowacyzk, Lucia Castiglia, Ornella Galesi, Emanuela Avola, Teresa Mattina, Marco Fichera, Maria Grazia Bruccheri, Giuseppa Maria Luana Mandarà, Francesca Mari, Flavia Privitera, Ilaria Longo, Aurora Curró, Alessandra Renieri, Boris Keren, Perrine Charles, Silvestre Cuinat, Mathilde Nizon, Olivier Pichon, Claire Bénéteau, Radka Stoeva, Dominique Martin-Coignard, Sophia Blesson, Cedric Le Caignec, Sandra Mercier, Marie Vincent, Christa L Martin, Katrin Mannik, Alexandre Reymond, Laurence Faivre, Erik Sistermans, R Frank Kooy, David J Amor, Corrado Romano, Joris Andrieux, Santhosh Girirajan
Faculty, Staff and Student Publications
Variable expressivity of disease-associated variants implies a role for secondary variants that modify clinical features. We assessed the effects of modifier variants on the clinical outcomes of 2,455 individuals with primary variants. Among 124 families with the 16p12.1 deletion, distinct rare and common variant classes conferred risks for specific developmental features, including short tandem repeats for neurological defects. Network analysis suggested distinct mechanisms involving 16p12.1 genes and secondary variants specific to each proband. Within disease and population cohorts of 976 individuals with the 16p12.1 deletion, we found opposing effects of secondary variants on clinical features across ascertainments. Additional analysis of …
Microplastic Exposure Alters Tubulin Leading To Alterations In Insulin Secretion By Pancreatic Beta Cells, Anakaren Garcia
Microplastic Exposure Alters Tubulin Leading To Alterations In Insulin Secretion By Pancreatic Beta Cells, Anakaren Garcia
Honors Program Theses and Research Projects
Abstract
Diabetes mellitus is a metabolic disorder characterized by elevated blood glucose levels due to impaired insulin secretion or diminished cellular response to insulin (resistance). Pancreatic β-cells depend on a well-organized cytoskeleton, particularly microtubules composed of α- and β-tubulin heterodimers, to transport insulin granules to the plasma membrane during glucose-stimulated insulin secretion (GSIS). Disruption of microtubule organization can impair granule trafficking and reduce insulin release. However, emerging environmental toxicants such as microplastics that interfere with β-cell cytoskeletal function remains largely unexplored.
Microplastics (MPs) are small plastic particles (< 5 mm) that have become widespread environmental contaminants and can enter biological systems. Previous studies have shown that MPs can induce cellular stress and protein misfolding, but their effects on microtubules in pancreatic β-cells are not well characterized. This study investigates whether exposure to fluorescent polystyrene microplastics alters microtubule organization and insulin secretion in βTC-6 cells.
βTC-6 cells were treated with 10 µg/mL of fluorescent polystyrene microplastics for …
Predicting, Culturing, And Characterizing Beneficial And Detrimental Strains Associated With Plant Phenotypes., Anastasiia Onyshchenko
Predicting, Culturing, And Characterizing Beneficial And Detrimental Strains Associated With Plant Phenotypes., Anastasiia Onyshchenko
Arts & Sciences Graduate Student Theses and Dissertations
Modern agriculture’s reliance on chemical fertilizers has greatly increased crop yields but has also contributed to soil degradation, environmental pollution, and unsustainable resource use. Plant growth–promoting rhizobacteria offer a sustainable alternative, enhancing plant growth through mechanisms such as nitrogen fixation, phosphate solubilization, siderophore production, and phytohormone modulation, while also protecting plants against pathogens and abiotic stresses. However, soil microbial communities are highly diverse and structurally complex, making the isolation of individual beneficial strains challenging. Traditional approaches rely on selective media and labor-intensive phenotypic screening, which often capture only a small fraction of soil diversity. To overcome these limitations, we combined …
Analysis Of Source–Sink Organ Dynamics In Kaffir Lime (Citrus Hystrix Dc.) At Different Plant Ages, Siti Auliya Rahma, Rahmat Budiarto, Syariful Mubarok
Analysis Of Source–Sink Organ Dynamics In Kaffir Lime (Citrus Hystrix Dc.) At Different Plant Ages, Siti Auliya Rahma, Rahmat Budiarto, Syariful Mubarok
Jurnal Kultivasi
Kaffir lime (Citrus hystrix DC.) is a leafy spice commodity widely used as a culinary ingredient, in bio-pharmaceuticals, and as a raw material for essential oil production. Despite its high demand, leaf productivity remains relatively low, highlighting the need for improved cultivation practices. A better understanding of source–sink dynamics is essential, as leaf production is strongly influenced by the balance between assimilate-producing and assimilate-consuming organs. Therefore, this study aimed to evaluate the source-sink capacity of kaffir lime plants of different ages as a preliminary step toward identifying cultivation strategies to enhance leaf production. The experiment was conducted at Bale Tatanen …
Comparative Analysis Of Color, Texture, And Water Content In Three Shallot Cultivars At Different Harvest Ages, Rahma Wati Lestari, Kusumiyati, Syariful Mubarok
Comparative Analysis Of Color, Texture, And Water Content In Three Shallot Cultivars At Different Harvest Ages, Rahma Wati Lestari, Kusumiyati, Syariful Mubarok
Jurnal Kultivasi
Shallots are a major horticultural commodity with high economic value. The quality of shallots is determined not only by the quantity of the harvest but also by physical characteristics such as bulb color, texture, and water content. This study aims to evaluate the differences in these physical parameters in three popular local cultivars: Brebes, Sumenep, and Tuktuk, harvested at 56, 63, and 70 days after planting (DAP), respectively. This research uses a Randomized Block Design consisting of 9 treatment combinations and analyzed using the SmartstatXL application. Color measurements are conducted using the CIELAB method and converted to CIELCH and RGB …
Role Of Nano Edible Coating, Packaging, And Storage Temperature In Maintaining Color, Moisture Content, And Phenolic Compounds Of Straw Mushroom, Kiki Nuratni Sitompul, Syariful Mubarok, Kusumiyati
Role Of Nano Edible Coating, Packaging, And Storage Temperature In Maintaining Color, Moisture Content, And Phenolic Compounds Of Straw Mushroom, Kiki Nuratni Sitompul, Syariful Mubarok, Kusumiyati
Jurnal Kultivasi
Straw mushrooms are among the most sought-after edible mushrooms, but their harvest is highly perishable due to their high respiration and transpiration rates, leading to a decline in quality during storage. The application of nano edible coating can cover the surface of straw mushrooms and maintain their freshness, while packaging and storage at low temperatures can maintain quality by inhibiting respiration and enzymatic activity. This study aims to evaluate the effects of nano edible coating, packaging types, and different storage temperatures on the color, moisture content, and phenolic compounds of straw mushrooms. The study was conducted at the Horticulture Laboratory, …