Digital Commons Network^™

Synthesis And Characterization Of Ti-Enhanced F75/Ha Functionally Graded Materials Fabricated By Powder Metallurgy, Afrah M. Al Hussainey, Aseel Mustafa, Randa Kamel Hussain

Karbala International Journal of Modern Science

Functionally graded materials (FGMs) are a highly advanced class of biomaterials with graded structure and properties, enabling the fabrication of physiologically and mechanically compatible materials for use in various medical devices. This study aims to produce a functional-grade material based on a cobalt-chromium-molybdenum alloy (F75) reinforced with 4% titanium (Ti) and hydroxyapatite (HA). This will enhance the material's mechanical properties, corrosion resistance, and bioactivity, making it suitable for use as a bone substitute. The natural eggshells were washed, burnt, and chemically processed to form hydroxyapatite with a Ca/P proportion of 1.67. FTIR showed that phosphate and OH groups were separate, …

Long-Term Variability Of Air Quality And Greenhouse Gas Emissions From Rice Crop Burning In Punjab During 2012–2020, Harsimranjit Kaur Romana, Dericks Praise Shukla, Ramesh P. Singh

Mathematics, Physics, and Computer Science Faculty Articles and Research

Punjab, India's primary rice and wheat production hub, has witnessed rapid expansion of paddy cultivation over the past two decades, driven by minimum support price incentives, changes in government policies, alignment of sowing with the monsoon season and the adoption of high-yielding varieties. This transition has intensified groundwater extraction and shortened the fallow period between rabi and kharif crop seasons, reducing the window between rice harvesting and wheat sowing, leading to widespread open-field burning of rice residue and recurrent post-monsoon air-quality deterioration across the Indo-Gangetic Plain. Despite numerous short-term or single-pollutant assessments, a spatially resolved, multi-pollutant and multi-decadal evaluation linking …

Predicting Tart Cherry Stem Water Potential Using Uav Multispectral Imagery And Environmental Data Via Symbolic Regression, Anderson L. S. Safre, Alfonso Torres-Rua, Kurt Wedegaertner, Brent Black, Brennan Bean, Burdette Barker, Matt Yost

Civil and Environmental Engineering Faculty Publications

Tart cherry is an important fruit crop in Utah, where irrigation is essential due to arid conditions. Precision irrigation requires reliable indicators of plant water status, and stem water potential (Ψ_stem), is among the most sensitive though labor-intensive and spatially limited. This study develops Ψ_stem estimation models using high-resolution multispectral Unmanned Aerial Vehicle (UAV) imagery combined with meteorological and soil moisture data, applying Symbolic Regression (SR). Results show a stronger correlation between optical bands and Ψ_stem during the pre-harvest period. Among 85 vegetation indices, the Red Chromatic Coordinate (RCC) index performed best (R² = 0.67). …

Redesigning Online Graduate Orientation To Foster Academic Resilience And Prevent Underperformance, Stella Michael-Makri, David E. Rodriguez

Journal of Academic Underperformance

Graduate students in fully online programs often begin their academic journey without adequate preparation for the emotional, structural, and cultural challenges of graduate-level work. For students who are first-generation, racially marginalized, international, or returning to education after time away, this lack of scaffolding can lead to early disengagement, underperformance, or attrition. Orientation, often treated as a checklist of logistical tasks, represents a missed opportunity for meaningful academic intervention. This manuscript proposes a five-module conceptual model for online graduate orientation designed to proactively support online graduate students in the domains of emotional regulation and academic identity, time management and executive functioning, …

Integrating The Glycemia Risk Index Into Clinical Practice And Research: A Consensus Report, Guillermo E Umpierrez, Viral N Shah, Veronica Brady, Mark A Clements, Juan Espinoza, Elizabeth Healey, Michael A Kohn, David M Maahs, Ralph Oiknine, Jane J Seley, Steven P Weitzman, David Kerr, Halis K Akturk, Grazia Aleppo, Mohammed E Al-Sofiani, Eda Cengiz, Francis J Doyle, Osagie Ebekozien, Steven V Edelman, Laya Ekhlaspour, Guido Freckmann, Lutz Heinemann, Irl B Hirsch, Victoria C Hsiao, Sun H Kim, Boris Kovatchev, Rayhan A Lal, Marcus Lind, Julia K Mader, Nestoras Mathioudakis, Tracey Mclaughlin, Sultan A Meo, Deborah A Osafehinti, Moshe Phillip, Priya Prahalad, David Scheinker, Michael P Snyder, Jing Wang, Jenise C Wong, Eugene E Wright, Mandy M Shao, Agatha F Scheideman, Ashley Y Dunova, David C Klonoff

Faculty, Staff and Student Publications

A panel of experts in the use of continuous glucose monitoring (CGM) data in the treatment of diabetes met in Burlingame, California on October 27, 2025 to discuss the utility of the glycemia risk index (GRI) for clinical care research and population health management. The GRI composite metric is a single number (on a 0-100 percentile scale-lower is better) based on an expert-determined weighting of the seven individual components in the existing ambulatory glucose profile (AGP). The GRI describes the quality of glycemia based on glucose values collected in a 14-day CGM tracing, thus providing additional insights into CGM profiles …

Main-Chain Ion-Pair Polybenzimidazole Membranes Enabling Reduced-Temperature Ht-Pemfc Operation (Down To 120°C), Huina Lin, Brian C. Benicewicz

Faculty Publications

Proton exchange membrane (PEM) fuel cells are promising for clean and efficient energy conversion across diverse applications. High-temperature PEM fuel cells (HT-PEMFCs) using phosphoric acid (PA)-doped polybenzimidazole (PBI) can operate up to 200°C, but at lower temperatures, water-induced PA loss often leads to performance degradation and reduced durability. In this work, we present a new class of main-chain ion-pair PBI membranes by integrating the imidazolium-biphosphate ion-pair units directly into the PBI backbone. This design results in membranes with high acid content, stronger acid-polymer interactions and stabilized acid retention. In single-cell tests, the Im⁺-PBI15-3 wt.% exhibits peak power densities …

Assessing The Performance Of A 3d Printed Pennsylvania-Style Black Light Moth Trap, Christopher B. Brown, Eva S. Conley, Peter White

The Great Lakes Entomologist

Passive light traps have long been a popular method used for trapping moths and other night-flying insects. Recent changes in the availability of equipment necessitate the development of accessible and effective alternatives for insect monitoring. This study assesses the performance of a 3D-printed Pennsylvania-style black light moth trap compared to the formerly available commercial BioQuip trap and investigates the impact of funnel size on catch rates. Our 3D-printed trap was compared to the BioQuip trap over ten trap-nights in Central Michigan. Results indicate that commercial BioQuip traps consistently captured significantly more moths than the 3D-printed prototype. An additional experiment evaluating …

Freshwater Quality For Recreation, Heather Nix, Masha Bokar

Forestry and Natural Resources

South Carolina has many water resources that provide tremendous opportunities for people to enjoy water-based recreational activities, such as swimming, boating, and fishing. Participation in these activities produces significant economic benefits and supports many jobs throughout the state. However, at times, water quality may be unsafe for immersion or skin contact due to high levels of pollutants, such as bacteria or cyanotoxins. It is important for people to be aware of potential concerns and understand methods for determining if a waterbody’s current conditions are likely to be safe for primary or secondary recreation.

Physical And Chemical Study Of Interaction In The Urea–Valine System For The Creation Of Modified Liquid Nitrogen Fertilizers, Suvonkul Erkhanovich Nurmonov, Saydullo Khamidovich Azimov

Chemical Technology, Control and Management

This study reports the results of a comprehensive physicochemical investigation of the urea–L-valine binary system, conducted to validate its potential as a modified base for liquid nitrogen fertilizers.

By utilizing the methods of isomolar series, visual-polythermal analysis, X-ray phase (XRD) and single-crystal X-ray diffraction (SC-XRD), synchronous thermal analysis (TGA/DTA), and FT-IR spectroscopy, it was determined that the interaction between components in both aqueous solutions and the solid phase results in the formation of molecular associates stabilized by hydrogen bonds, without the formation of new stoichiometric compounds.

The concentration and temperature limits of the system's stability were defined, revealing a reduction …

Self-Aware Quantum-Inspired Routing Framework For 6g And Quantum Networks, Haitham M. Abdelghany, Mohamed M. Ashour

Mansoura Engineering Journal

This paper introduces a quantum-hybrid-aware routing framework that incorporates the concepts of quantum computing with meta-cognitive learning to improve adaptability, reliability, and awareness in dynamic quantum networks. The proposed system accommodates a new IoT, edge computing and 6G system, where routing schemes should be flexible and robust and have cross-topology functionality. Conventional methods of quantum reinforcement learning can be characterized by a trade-off between exploration and decision stability. To cope with this, the proposed self-aware hybrid architecture is a combination of quantum-enhanced learning and a meta-cognitive awareness layer to allow autonomous agents to monitor performance and adjust routing strategies on …

Targeting Cancer With T Cells: Preclinical And In Silico Insights To Improve Immunotherapies, Nina Obertopp

USF Tampa Graduate Theses and Dissertations

T-cell–based immunotherapies are often constrained by limited trafficking and persistence in tumors and by functional exhaustion under chronic antigen exposure. This dissertation addresses these barriers through two distinct strategies: (i) preclinical studies testing how radiation therapy modulates tumor-infiltrating lymphocytes (TIL) therapy, and (ii) agent based modeling (ABM) to optimize treatment day treatment-free intervals (TFI) in T-cell engager (TCE) therapy. (i) In a human papillomavirus–positive (HPV⁺) head-and-neck cancer (HNC) model, a single local-dose of RT (8 Gy) delivered five days before tumor harvest increased the success and functional quality of ex vivo TIL outgrowth from tumor fragments, enriching polyfunctional CD8⁺ subsets. …

The Need For Developing Psychologically Informed Physical Therapy Education, Dustin Cox

Journal of Applied Disciplines

Chronic pain presents a multifaceted challenge for healthcare providers, often impacting patients' physical, emotional, and psychological well-being. Research indicates that individuals with chronic pain process pain through emotional and reward pathways in the brain, underscoring the need for integrative treatment approaches. Evidence supports the effectiveness of combining psychological interventions with physical rehabilitation to improve outcomes. Acceptance and Commitment Therapy (ACT), a mindfulness-based behavioral therapy, has shown promise in addressing the psychological dimensions of chronic pain. However, physical therapists often lack formal training in ACT. This study protocol was designed to explore effective methods for educating physical therapists in ACT principles …

Plaster Creek Watershed Management Plan: Chloride Addendum, Plaster Creek Stewards

Watershed Reports

This addendum complements the 2008 Plaster Creek Watershed Management Plan (WMP), which tells the full story of the Plaster Creek Watershed’s current condition, impairments, and need for restoration. This addendum focuses on chloride, an emerging pollutant of concern in Michigan that was not addressed in Plaster Creek’s 2008 WMP. This addendum meets the nine elements required by the United States Environmental Protection Agency (EPA) for a watershed management plan to be officially approved; as such, its content and layout are intended for a technical audience.

(Si16-21) Dynamical Study Of A Hassell-Varley Model With Nonlinear Harvesting And Fear Effect In Prey, Aditya Bhattacharya, Anindita Bhattacharyya

Applications and Applied Mathematics: An International Journal (AAM)

In this article, a one predator-one prey model incorporating Richards’ type growth in prey population, Hassell-Varley type functional response and Michaelis-Menten type prey harvesting is proposed and analyzed. Richards’ type growth with fear factor is incorporated in the proposed model to generalize the reduction effect of predator-induced fear on the rate of growth of the prey population. Positivity and boundedness of the system’s solutions are first established to ensure biological feasibility of the model. Existence and stability conditions of various types of equilibrium points associated with the model such as trivial equilibrium, axial (predator–free) equilibrium and coexistence equilibrium are obtained …

Alfred Russel Wallace Notes 39. What About Wallace's 'Agnosticism'...?, Charles H. Smith

Faculty/Staff Personal Papers

Alfred Russel Wallace (1823−1913) seems to have distinguished his earlier years of agnosticism from his later period as a spiritualist, but a closer look at the situation suggests he actually remained an agnostic all the way through to the end of his life. The confusion is occasioned by a lack of terminology that can be applied to his position, which most closely resembles a Spinozian manner of thinking.

In Vitro Pharmacological Evaluation Of Novel Cmpi Derivatives As Selective Positive Allosteric Modulators Of The Alpha4 Beta2 Nicotinic Acetylcholine Receptor, Josue Gaona, Nataly Sanchez, Wilder Felix, Nathalia Menegasso, Brisa Cea, Ganesh Thakur, Ayman K. Hamouda

School of Medicine Student Publications and Presentations

Nicotinic acetylcholine receptors (nAChRs) contribute to the pathogenesis of neurodegenerative diseases such as Parkinson’s disease (PD), where degeneration of dopaminergic and cholinergic neurons disrupts neurotransmission. The (α4)₃(β2)₂ nAChR subtype is expressed on affected neuronal populations and represents a promising therapeutic target. Positive allosteric modulators (PAMs) may enhance receptor function while preserving endogenous signaling. We evaluated chemical derivatives of CMPI [3-(2-chlorophenyl)-5-(5-methyl-1-(piperidin-4-yl)-1H-pyrazol-4-yl)isoxazol] as selective PAMs of (α4)₃(β2)₂ nAChRs. Two-electrode voltage-clamp recordings were performed in Xenopus laevis oocytes expressing defined receptor stoichiometries to assess potentiation and generate dose–response curves. Cytotoxicity was assessed in HEK cells using the MTT assay. Substitutions at the pyrazole …

College Of Natural Sciences 2025 Year-End Publication, College Of Natural Sciences

College of Natural Sciences Newsletters and Reports

Page 2 Dean's Message 
Page 3 Department Highlights 
Page 4 One Day for State 
Page 5 Ice cores reveal volcanic eruptions in 13th century 
Page 5 How do our cells interpret stress 
Page 6-7 Faculty Excellence
Page 8 New chemical biology consortium will accelerate cancer research
Page 9 SDSU to combat crop disease, biofilms in new NSF-back project 
Page 9 Science as Art Competition 
Page 10-11 Student Excellence  
Page 12 SDSU researcher developing natural alternative to synthetic dyes
Page 12 Browning Retired
Page 13 Quantum technologies through NSF-backed project
Page 13 NASA Funds CNS Development of Model
Page 14 GGS …

The Modern Sisyphus Blows Leaves: Attitudes And Impacts Regarding Leaf Litter Removal On A Suburban Campus, A. C. Nony, M. R. Mcclung, M. L. Reid

Journal of the Arkansas Academy of Science

Leaf litter habitat disruption in suburban spaces stems from the prevalence of “lawn culture,” that is, the accepted societal norm that land immediately surrounding humans or meant for human recreational use should be clean, tidy, controlled, and aesthetically pleasing, above other considerations. When leaf litter on residential and recreational lawns is cleared, it removes vital habitat for organisms of several taxa, especially species that rely on litter as a moisture and temperature-controlled substrate for overwintering. We administered an opinion survey to students, staff, and faculty at Hendrix College, a highly residential and suburban campus in Conway, Arkansas, to assess views …

A Critical Review Of Statistical, Signal Processing And Machine Learning Methods For Continuous And High-Frequency Water Quality Data Improvement, A.T. Badrudeen, D. Sahoo, Calvin Sawyer, Jeremy Pike, R.D. Haramel

Publications

In the digital water world, high-frequency water quality monitoring from sensors is crucial for capturing rapid changes, especially during storm events or discharge fluctuations, in which important signals can occur at sub-hourly intervals. These signals are represented in a time series and can sometimes be irregular, noisy, and prone to missing values or errors due to buried conditions, sediment interference, and signal loss. The fine resolution of reporting also increases the risk of sensor errors and data loss, necessitating effective correction methods to ensure the accuracy and usability of the data. This literature review investigates the current state of time …

The Application, Construction, And Validation Of Hidden Markov Model Profiles For Carbonic Anhydrase Enzymes, Samuel F. Kaplan

Master's Theses

Carbonic anhydrases (CAs) catalyze the reversible hydration of CO2 and have evolved independently at least eight times, resulting in structurally distinct enzyme families (α, β, γ, δ, ζ, η, θ, ι). Traditional sequence alignment methods struggle to classify these convergently evolved proteins because their sequential similarity does not reliably indicate functional or evolutionary relationships. Many CA sequences in public databases are annotated generically without family assignments, and prior computational approaches have focused predominantly on the three well characterized families (α, β, γ), leaving the five recently discovered classes without robust classification tools. Family level assignment is often a prerequisite for …

Trophic Structure And Mercury Bioaccumulation In Walleye And Yellow Perch In The Upper And Lower Red Lake Basins, Marissa Pribyl

Biology Graduate Theses

Mercury is a persistent global contaminant that biomagnifies through aquatic food webs, with dietary and environmental factors serving as the primary drivers of accumulation in fishes. Trophic structure and methylmercury dynamics in Walleye (ogaa; Sander vitreus) and Yellow Perch (asaawens; Perca flavescens) were investigated in the Upper and Lower Red Lake basins in Red Lake, Minnesota, during 2024-2025. Diets of Walleye and Yellow Perch were assessed through stomach dissections, and tissue samples from both species were analyzed for total mercury concentrations. Additional analyses included shiners (gigoozens; Notropis spp., Hudsonius spp.) along with a variety of freshwater fish and …

Wayne E. Sabbe Arkansas Soil Fertility Studies 2025, Nathan A. Slaton

Arkansas Agricultural Experiment Station Research Series

Rapid technological changes in crop management and production require that the research efforts be presented in an expeditious manner. The contributions of soil fertility and fertilizers are major production factors in all Arkansas crops. The studies described within will allow producers to compare their practices with the university’s research efforts. Additionally, soil-test data and fertilizer sales are presented to allow comparisons among years, crops, and other areas within Arkansas.

Comparison Of Analytical Techniques From The Extraction Of Bioactive Compounds From Kratom, Curry, Ginger, And Turmeric, Riley Bruno

Honors Program: Senior Projects (Public)

Plants, herbs, and spices have been used as medicines for thousands of years. Early civilizations often attributed healing properties of plants to magical or divine forces. However, as chemistry and analytical technology advanced between the 16th and 18th centuries, scientists began to understand that bioactive compounds within the plants actually caused these effects. Today, natural products remain extremely important in drug discovery. As the number of newly developed synthetic drugs declines, there has been renewed interest in identifying biologically active molecules from plants. Bioactive molecules are a group of diverse chemical compounds that stimulate a response in living tissues. The …

A Comprehensive Biomechanical Material Characterization Of The Human Breast Fibro-Structural Support System, Aroj Bhattarai, Gregory P Reece, Kristy K Brock, Krishnaswamy Ravi-Chandar

Faculty, Staff and Student Publications

Breast surgery for aesthetic purposes, such as breast augmentation or breast reduction, and breast reconstruction after cancer treatment require an accurate structural (anatomical) and mechanical (functional) understanding of the breast components, including the fascial-ligamentous support system of the breast, to achieve optimal results. This paper aims to provide a comprehensive description of the mechanical behavior of the ligamentous and fascial connective tissues of the human female breast. Fasciae and ligaments obtained from 17 patients between 35 and 85 years of age who were undergoing mastectomy and three female cadavers were tested. Uniaxial tensile tests were conducted, and three constitutive models …

Signatures Of The Anthropocene: Population Genomic Structure Detected In Pennsylvania Coyotes, Craig A. Marshall, Julia Halo, Kyle Van Why, Yeraldi Loera, Stavi R. Tennenbaum, Casey Burton, Ariana Di Landro, Dominic Dominguez, Daniel Duncan, Madison Machado, Catalina Posada, Stephen J. Gaughran, Madison Lichak, Kristin Brzeski, Elizabeth Heppenheimer, Bridgett Vonholdt

Michigan Tech Publications

Coyotes (Canis latrans) expanded across eastern North America in the last century and are ecological generalists capable of thriving across diverse habitats. Broad genetic surveillance has reported little spatial genetic patterning for this highly dispersive species. Here, we explore the genome-wide signatures of spatial patterns found in a 10-year study of 1199 coyotes from northeastern United States, with a temporal analysis of Pennsylvania coyotes. Despite their broad dispersal capability, we detected subtle but significant population structure, with two genetic clusters that have a weak clinal transition zone. This partitioning aligned qualitatively with patterns of human population density and activity. We …

Unpacking Drivers Of Heterotrophic N2 Fixation Across Aquatic Redox Gradients: A Mathematical Model With Bioenergetic And Stoichiometric Constraints, Corday R. Selden, Rebecca A. Everett, Halvor M. Halvorson, Megan Berberich, Luca Schenone, Angela Peace, Renn Schipper, Edwin Cruz-Rivera, James Powell, Keisuke Inomura, Robinson W. Fulweiler, Amy Marcarelli, J. Thad Scott

Michigan Tech Publications

N2 fixation by aquatic organoheterotrophs supplies bioavailable nitrogen to the biosphere and thereby supports ecosystem production; yet the factors which drive this activity are poorly understood. Here, we present a generalized chemostat model to investigate stoichiometric and energetic constraints on free-living heterotrophic diazotrophs across gradients in redox state, resource quantity/quality, and resource stoichiometry. The model couples nutrient uptake and allocation functions to predict elemental fluxes with an energy dissipation model to calculate growth efficiency. After constraining model parameters with relevant culturing (e.g., Azotobacter) and environmental literature, we assessed model sensitivity to these parameters using Latin Hypercube Sampling and the statistical …

Exosome Engineering For Blocking Gut Dysbiosis And Inducing Cell Death Mechanisms In Glioblastoma Multiforme, Ahalya Muraleedharan, Karthik Rangavajhula, Swapan K. Ray

Faculty Publications

Glioblastoma multiforme (GBM) is the most lethal primary brain tumor in adults. Emerging evidence endorses that gut dysbiosis contributes to GBM progression through the gut–brain axis (GBA), promoting inflammation and therapeutic resistance via abnormal short-chain fatty acid production and cytokine dysregulation. Exosomes, naturally occurring nanovesicles (30–150 nm), offer promising therapeutic potential due to their blood–brain barrier permeability, biocompatibility, and versatile cargo capacity. This review examines exosome engineering strategies for dual targeting: inhibiting alterations in gut microbiome and inducing regulated cell death mechanisms such as apoptosis and ferroptosis in GBM. We describe exosome engineering with detailed focus on cargo loading approaches …

Towards The Assessment Of E-Flows: A Fish-Based Approach For The Tiber River Basin (Central Italy), Antonella Carosi, Francesca Lorenzoni, Fatemeh Zarei, Rachele Brustenga, Lucio Di Matteo, Daniela Valigi, Corrado Cencetti, Carlo Cardellini, Stefano Casadei, David Cappelletti, Massimo Lorenzoni

Turkish Journal of Zoology

Estimating ecological flows (EFs) in rivers is crucial for meeting the Water Framework  Directive (WFD) 2000/60/EC goals. To develop an EF model, it is  essential to use biological indicators to reliably record the impacts of human-induced  alterations on aquatic ecosystems. The adaptability of fish to annual flow variability  makes them a significant biological quality element (BQE). Consequently, using fish  as bioindicators is a powerful tool for assessing the impact of changes in the  hydrological regime on the natural communities within a river system. The new index  of the ecological status of fish communities (NISECI) is a methodology developed in  Italy …

Plants Have A Chemical Defense To Protect Themselves From Herbivory, Isis Cordova

Research on Capitol Hill

All plants produce compounds for survival. My work focuses on how plants remember past attacks and whether that memory leads to stronger/faster responses.

At Utah Lake, Large Changes In Water Level Impact The Restoration Of Native Plant Species, Mac Havens

Research on Capitol Hill

Native plant communities at Utah Lake matter for top-class recreation opportunities, migratory bird populations, June Sucker recovery efforts, and local economies.