Digital Commons Network^™

Ecological Consequences Of Variable Glacial Melting On Arctic Biodiversity: Trophic Shifts And Community Dynamics, Aislyn Malone, Audrey Swart

Celebrating Scholarship and Creativity Day (2018-)

Our project investigated the profound impacts of increasing glacial melting on various trophic levels, habitats, and other ecological processes.

Spatiotemporal Changes In The Imperiled And Diverse Mussel Assemblage Of The Spring River In Kansas In Response To Known And Emerging Pollutants, Joshua Holloway

Electronic Theses & Dissertations

Kansas was historically home to 50 species of freshwater mussels, of which 42 remain extant. The Spring River of southeastern Kansas is home to 34 of the remaining 42 mussels, many of which are imperiled. Elevated metal concentrations that resulted from past lead and zinc mining in the Tri-State Mining District historically imperiled Spring River mussels, but this threat has abated over the last 20 years. Ammonia pollution may have replaced the threat of metals, however, with potentially severe consequences for Spring River mussels. Our objectives were to evaluate contemporary mussel assemblage structure, in addition to spatiotemporal trends in the …

A Greek Inscription From The Late Roman Period In Burial Cave 4 At Ben Shemen (Pp. 67–70), Leah Di Segni

'Atiqot

A Greek inscription, consisting of four lines, including the term “servants of Christ”, was found in a rock-hewn arcosolium burial cave (Cave 4) in Ben Shemen. The inscription was painted in red on a plastered section of the cave wall that had collapsed from above the eastern arcosolium. Based on palaeography, as well as the type of abbreviations used in the script, the tomb was used in the late third or early fourth centuries CE.

Mi‘Ilya: Evidence Of An Early Crusader Settlement (Pp. 63*–76*), Edna J. Stern

'Atiqot

A salvage excavation carried out on the upper hill of the village of Mi‘iliya exposed remains from the Late Bronze Age, Iron Age and Crusader period. Fifty-six diagnostic sherds, dating to the Crusader period, were found in a pit. Most of them represent local Crusader types, with a few belonging to imported types. The chronological range of the Crusader-period pottery dates from the mid-twelfth to the early thirteenth centuries CE.

Khan Gesher (Jisr El-Majami‘), Abdullah Mokary, Zvi Gal

'Atiqot

Khan Gesher is one of the earliest khans in Galilee. Three periods of occupation were documented at the site. The khan was first built during the Mamluk period as a square complex, with a central courtyard surrounded by rooms and halls. The halls served as stables, and the rooms and the central courtyard served non-residential functions, e.g., a gate, a water system, and a prayer room. Thus, the khan might have had a second story for housing travelers. During the Ottoman period, the building underwent changes and modifications. The khan was probably destroyed in the late eighteenth or early nineteenth …

Kettlebell Swings As A Conditioning Activity On Standing Power Throw: Exploring Post-Activation Performance Enhancement In Rotc Cadets, Knik Durman

Masters Theses & Specialist Projects

Post-activation performance enhancement (PAPE) is a neuromuscular phenomenon where high-intensity conditioning activities (CA) temporarily improve explosive performance. While resistance and ballistic exercises are well-studied for PAPE, the effectiveness of kettlebell swings (KBS) in enhancing Standing Power Throw (SPT) performance remains unclear. Given the SPT’s role in the Army Combat Fitness Test (ACFT), identifying effective PAPE strategies could improve ACFT scores. Using a randomized crossover design, this study examined whether KBS before the SPT enhanced throw distance in 19 ROTC cadets (male: n = 17, female: n = 2). Participants completed two conditions: (1) KBS (two sets of five reps with …

Factors Mediating The Reproductive Risk For Balanced Chromosomal Translocation Carriers, Talia Alter

The Science Journal of the Lander College of Arts and Sciences

Reciprocal balanced translocations occur when one part of a chromosome is exchanged with another, resulting in zero net loss of genetic material. While individuals with a balanced translocation are phenotypically normal, a translocation can cause increased risk of infertility, recurrent pregnancy loss, and the birth of a child with unbalanced chromosomes. In order to adequately guide an individual in their reproductive decisions, geneticists must be able to assess the risk of the patient’s unique translocation. An analysis of three recent studies reveals several factors which play a role in mediating the effects of balanced translocations and directly affect reproductive risk …

Presence Of Potential Nursery Habitat For The Lemon Shark In Mississippi Coastal Waters, Lindsay K. Bomgardner, P. O. Grammer, Angie Hoover, Anna Millender, Jeremy Higgs, Jill M. Hendon, Michael J. Andres

Gulf and Caribbean Research

No abstract provided.

Assessing Distribution And Density Changes Of The Ecosystem Engineers, Rockweed And Kelp, In Narragansett Bay, Ri, Rebecca Venezia

Open Access Dissertations

Climate change and anthropogenic stressors in marine costal habitats include increased sea surface temperatures (SST) and precipitation. The impacts of these stressors can affect ecosystem engineer species, which create three-dimensional habitat space in and provide various ecosystem services that modify and maintain ecosystem resources. In Narragansett Bay, RI, USA there is anecdotal evidence that the habitat forming species of kelp, Saccharina latissima, and rockweeds, Ascophyllum nodosum and Fucus spp, are changing but few long-term studies have been conducted to verify this. We compared the historical studies from the 1960s to 2010s on seaweeds in Narraganset Bay to modern SCUBA …

Intraspecific Variation In Plant–Fungal Interactions Across Tidal Elevation In A Salt Marsh, Torrie Hanley, Catherine Gehring, Ron Deckert, Behzad Mortazavi, Christina Richards, A. Randall Hughes

Biology Faculty Publications

Interspecific interactions vary depending on environmental and genetic factors, with intraspecific variation potentially altering these relationships. Specifically, intraspecific variation within host plants and their endosymbionts may affect above- and belowground interactions depending on environmental conditions. We examined how intraspecific variation within the salt marsh foundation species Spartina alterniflora and a common fungal root endosymbiont (Lulworthia sp.) affected their interactions. We conducted a glasshouse experiment comparing interactions between Spartina growth forms (tall-form from low marsh and short-form from high marsh) and Lulworthia isolates from different marsh locations, and a laboratory experiment exposing Lulworthia isolates from both endpoints of a tidal elevation …

Spatial Insight Of Kidney Sex-Dimorphism And Tumor Evolution, Chia-Kuei Mo

McKelvey School of Engineering Graduate Student Theses & Dissertations

The landscape of spatial biology research has transformed drastically in recent years allowing a comprehensive understanding of cellular organization and molecular mechanisms in various biological context. This thesis presents three complementary studies that advance our understanding of spatial organization in normal tissue biology and tumor evolution, utilizing cutting-edge spatial multi-omics approaches. The first study presents a comprehensive investigation of kidney sexual dimorphism across the lifespan, integrating six distinct technological platforms: single-nucleus transcriptomics, epigenomics, Visium spatial transcriptomics, Xenium single-cell resolution spatial transcriptomics, conventional immunofluorescence imaging, and co-detection by indexing (CODEX) multiplexed protein imaging. This multi-modal approach reveals that proximal tubules exhibit …

Antiangiogenic Therapy Combined With Immune Checkpoint Blockade In Urothelial Cancer: Systematic Review And Meta-Analysis, Mohammad Jad Moussa, Iuliia Kovalenko, Emanuele Crupi, Ekaterina Proskuriakova, Yimin Geng, Giuseppe Fallara, Raed Benkhadra, Daniele Raggi, Matthew T Campbell, Pavlos Msaouel, Omar Alhalabi

Faculty, Staff and Student Publications

Background: Antiangiogenic therapy had been tested in urothelial cancer (UC) without reaching the clinic.

Objective: We provide a systematic review and meta-analysis of trials to assess efficacy of immune checkpoint inhibitors (ICI) combined with antiangiogenic agents in UC.

Methods: Following PRISMA guidelines, we searched for trials with at least one arm of patients with UC treated with ICI plus antiangiogenics. Data were analyzed with the "meta" package from R using a one-staged frequentist meta-analysis.

Results: After screening 13,708 titles and abstracts, 9 studies were selected for analysis with 14 identified cohorts comprising 621 patients: 448 were ICI-naïve (ICI-N) and 173 …

The Foreigner In Our Midst: Jewish Rights Debates In Revolutionary France, William Evans

Best Integrated Writing

The debates surrounding Jewish rights during the French Revolution concerned many of the same subjects that divide the Western world today. The fear of the other, immigration as a political tool, and the disagreements over assimilation are all subjects which feature prominently today. In this essay Evans sets out to explore these debates while fairly assessing the historical informants.

Best Integrated Writing Fall 2024 - Complete Edition, Wright State University School Of Humanities And Cultural Studies, Kristie Mckiernan, Tracy Smith

Best Integrated Writing

Best Integrated Writing includes excellent student writing from Integrated Writing courses taught at Wright State University.

International Conference On Food Science, Nutrition And Agriculture, University For Business And Technology - Ubt

UBT International Conference

UBT Annual International Conference is the 13th international interdisciplinary peer reviewed conference which publishes works of the scientists as well as practitioners in the area where UBT is active in Education, Research and Development. The UBT aims to implement an integrated strategy to establish itself as an internationally competitive, research-intensive university, committed to the transfer of knowledge and the provision of a world-class education to the most talented students from all background. The main perspective of the conference is to connect the scientists and practitioners from different disciplines in the same place and make them be aware of the recent …

The Biological Significance Of Tumor Grade, Age, Enhancement, And Extent Of Resection In Idh-Mutant Gliomas: How Should They Inform Treatment Decisions In The Era Of Idh Inhibitors?, Martin J Van Den Bent, Pim J French, Daniel Brat, Joerg C Tonn, Mehdi Touat, Benjamin M Ellingson, Robert J Young, Johan Pallud, Andreas Von Deimling, Felix Sahm, Dominique Figarella Branger, Raymond Y Huang, Michael Weller, Ingo K Mellinghoff, Tim F Cloughsey, Jason T Huse, Kenneth Aldape, Guido Reifenberger, Gilbert Youssef, Philipp Karschnia, Houtan Noushmehr, Katherine B Peters, Francois Ducray, Matthias Preusser, Patrick Y Wen

Faculty, Staff and Student Publications

The 2016 and 2021 World Health Organization 2021 Classification of central nervous system tumors have resulted in a major improvement in the classification of isocitrate dehydrogenase (IDH)-mutant gliomas. With more effective treatments many patients experience prolonged survival. However, treatment guidelines are often still based on information from historical series comprising both patients with IDH wild-type and IDH-mutant tumors. They provide recommendations for radiotherapy and chemotherapy for so-called high-risk patients, usually based on residual tumor after surgery and age over 40. More up-to-date studies give a better insight into clinical, radiological, and molecular factors associated with the outcome of patients with …

Montane Molluscs: Factors Affecting Snails And Their Trematodes Throughout The Mountain Regions Of Arkansas, Taylor Michelle Fiedor

Student Theses and Dissertations

Spatial processes across both broad and fine scales are important for understanding ecosystem function. Broad-scale spatial processes can be defined as elevational, latitudinal, or longitudinal processes whereas fine-scale spatial processes represent movement and dispersal among habitat patches. Historically, studies on freshwater snail distributions have focused on fine-scale processes with secondary consideration given to spatial sampling. Species inventories for freshwater snails are outdated because historically snail species descriptions were based on shell morphology, which is highly plastic. In Arkansas, it is estimated that there are 36 freshwater snail species, but this estimate does not account for shell plasticity and does not …

Nationalism And The Federal State’S Agricultural Policies; The Politics Of Cassava In Zambia, 1953-1963, Kaluba Jickson Chama

Zambia Social Science Journal

During the Federal era, cassava played an important role in political mobilisation in Luapula Province. Nonetheless, the crop has seldom received attention in the otherwise rich historiography on African nationalism and anti-Federation struggle in present-day Zambia. Drawing on archival sources and oral history, and a reading of secondary sources, this article attempts to contribute to the historiography of cassava in Zambia and its contribution to the nationalist cause. The article examines the position of cassava in political mobilisation by nationalist politicians. It explores the link between the politics of cassava and those of nationalism. This article’s key argument is that …

Investigation Of The Environmental Factors Regulating The Biomass And Toxin Production Of The Benthic Cyanobacterium Microseira Wollei In Lake Wateree, South Carolina, Kara Clyburn

Theses and Dissertations

Impacts from anthropogenic activities and climate change are significantly altering nitrogen (N) cycling processes and biological productivity along the freshwater to marine continuum, and the acceleration rate of excessive N and phosphorus (P) concentrations entering aquatic environments is unprecedented. As a result, nutrient pollution is contributing to the increasing magnitude and duration of cyanobacterial harmful algal blooms (cHABs), oxygen (O2) depletion, loss of biodiversity, and impacts to human and ecosystem health. Lake Wateree, South Carolina (SC) is a freshwater drinking and contact recreational water resource with elevated symptoms of eutrophication, including the increasing prevalence of the N2 fixing benthic cyanobacterium …

Sustainability Of A Rocky Grassland Association Over Four Decades, K Torok, G Kosa

IGC Proceedings (1977-2023)

The monitoring of vegetation changes Is essential for predicting the direction of future changes. Historic Braun-Blanquet type relev6s of a grassland association were resampled after 4 decades. Ordination techniques were applied to the joint data set. Important displacement of the relev6s was observed in the ordination space, though there is no complete separation of the historic and recent relev6s. No consistent change in species number, no decrease in diversity was experienced, The displacement of relev6s was the consequence of shif'l in the spectrum of life strategies of species: invasion of annuals, The cause of this shif'l may be the increased …

Bat Humoral Immunity And Its Role In Viral Pathogenesis, Transmission, And Zoonosis, Anne A. Roffler, Daniel P. Maurer, Tamika J. Lunn, Tarja Sironen, Kristian M. Forbes, Aaron G. Schmidt

Biological Sciences Faculty Publications and Presentations

Bats harbor viruses that can cause severe disease and death in humans including filoviruses (e.g., Ebola virus), henipaviruses (e.g., Hendra virus), and coronaviruses (e.g., SARS-CoV). Bats often tolerate these viruses without noticeable adverse immunological effects or succumbing to disease. Previous studies have largely focused on the role of the bat’s innate immune response to control viral pathogenesis, but little is known about bat adaptive immunity. A key component of adaptive immunity is the humoral response, comprised of antibodies that can specifically recognize viral antigens with high affinity. The antibody genes within the 1,400 known bat species are highly diverse, and …

Clinical And Genomic Landscape Of Ras Mutations In Gynecologic Cancers, Ji Son, Yingao Zhang, Heather Lin, Oriol Mirallas, Pablo Alvarez Ballesteros, Mirella Nardo, Natalie Clark, R Tyler Hillman, Erick Campbell, Vijaykumar Holla, Amber M Johnson, Amadeo B Biter, Ying Yuan, Lauren P Cobb, David M Gershenson, Amir A Jazaeri, Karen H Lu, Pamela T Soliman, Shannon N Westin, Elizabeth D Euscher, Barrett C Lawson, Richard K Yang, Funda Meric-Bernstam, David S Hong

Faculty, Staff and Student Publications

Purpose: We aimed to describe RAS mutations in gynecologic cancers as they relate to clinicopathologic and genomic features, survival, and therapeutic implications.

Experimental design: Gynecologic cancers with available somatic molecular profiling data at our institution between February 2010 and August 2022 were included and grouped by RAS mutation status. Overall survival was estimated by the Kaplan-Meier method, and multivariable analysis was performed using the Cox proportional hazard model.

Results: Of 3,328 gynecologic cancers, 523 (15.7%) showed any RAS mutation. Patients with RAS-mutated tumors were younger (57 vs. 60 years nonmutated), had a higher prevalence of endometriosis (27.3% vs. 16.9%), and …

Operation Villagization And Its Implications For Wildlife Conservation In South-Western Serengeti, Tanzania: The Case Of Maswa Game Reserve, Ca. 1970s–1980s, Beny Nampesya, Hezron Kangalawe

Journal of Humanities and Social Sciences

Operation Villagization in Tanzania attracted the attention of many scholars, including historians, inside and outside the country. This is because it is one of the major policies in the history of Tanzania that affected many sectors. Despite the extensive scope of these studies, minimal attention has been devoted to exploring the connections between this operation and wildlife conservation. The current article uses the case of the Maswa Game Reserve (MGR) to examine the extent to which the operation affected wildlife resources conservation. In essence, it argues that poor implementation of the operation led to enormous encroachments in the MGR, which …

Characterizing The Role Of The Complement Receptor C3ar In Regulating Inflammatory Responses And Mitochondrial Function In Activated Macrophages, Jesse Alan Corcoran

Dissertations and Theses

The complement system is an integral part of the innate immune response, and consists of a series of proteins that are mostly (although not exclusively) synthesized in the liver that circulate in the plasma as inactive precursors, as well as receptors on the surface of immune cells. In immune cells such as macrophages, recognition of pathogens by Toll-like receptors (TLRs) leads to the initiation of inflammation and triggers complement activation through a coordinated sequential enzyme cascade that results in the production of bioactive C3a, which interacts with membrane-bound receptor C3aR to regulate innate immune cell function and outcome of bacterial …

Methods To Manage Survey Error Within Economic Contribution Analysis, Madison Jane Plaisance

LSU Master's Theses

The primary objective of this research was to employ strategical methodological approaches to assess the economic value of specific sub-sectors of the green industry within Louisiana. I specifically focused on addressing errors associated with utilizing survey data as the primary data source in such analyses and utilizing approaches such as post-survey stratification and bootstrapping techniques to mitigate these errors.

To achieve this aim, a group of green industry professionals and I selected sectors for analysis based on horticultural licenses issued by the Louisiana Department of Agriculture and Forestry (LDAF). Through collaboration with advisors from the Louisiana Nursery and Landscape Association …

Parkinson's Disease - Association With Anxiety, Depression, And Sleep Disorders, Isabella J. Boroje

Doctoral Dissertations and Projects

Parkinson’s disease (PD) is a progressive neurological disorder presenting with motor symptoms, such as tremors at rest, bradykinesia, rigidity, and gait instability, and non-motor symptoms, such as anxiety, depression, excessive daytime sleepiness (EDS), and REM Sleep Behavior Disorder (RBD). The purpose of this study was to examine the associations of anxiety, depression, and EDS scores with being Prodromal (PPD) - at risk of developing the disease (PPD), having been diagnosed with PD, or being a Healthy Control (HC) using a multinomial logistic regression model. Additional analysis examined RBD scores and their difference across PPD, PD, and HC cohorts. The study …

The Biltmore Forest School And The Establishment Of Forestry Education In America, Dan Barry Croom

Journal of Research in Technical Careers

The Biltmore Forest School, despite its unusual existence within the affluent Biltmore Estate, played a crucial role in the early 20th-century American forestry movement. Founded by Carl A. Schenck and supported by George Vanderbilt II, the school aimed to educate foresters and promote sustainable forest management. However, many aspects of the Biltmore experiment failed due to the new and untested nature of forestry science in America. This experiment exposed a fundamental divide in forestry education, with Gifford Pinchot advocating for conservation-centered teaching while Schenck believed in the economic viability of lumber production. Ultimately, the Biltmore Forest School offered valuable vocational …

What's In A Name? Plant Naming As Cultural Artifact And Story In The Midwestern United States, Sophie Wesseler

Undergraduate Theses

This project sought to collect and contextualize the historical and contemporary names given to plants by inhabitants of the Midwestern United States, understanding plant names as cultural artifacts that can offer insight into the communities in which they were created and evolved. Formatted as a series of entries, this collection gathered these names and contextualized them within other artifacts of cultural significance, such as art or poetry, and alongside historical research on their origins and cultural environments. Examining plant names through the fields of linguistics, semiology, anthropology, cultural studies, taxonomy, and ethnobotany, this work traces the names of various plants …

Competition And Criticality In Cortical Neural Circuits Underlie Behavior And Optimize Working Memory, Jacob Harrison Barfield

Graduate Theses and Dissertations

One of the primary goals of neuroscience is to explain how brain function emerges from dynamic interactions among large populations of neurons. A long-standing hypothesis at the interface of physics and neuroscience posits that neural circuits may operate close to the critical point of a phase transition. In this dissertation, we will investigate a new form of criticality and the implications that it has in working memory and the generation of voluntary body movements. We will utilize this new form of criticality to investigate the functional benefits that can be harnessed by operating near the critical point when performing working …

Characterizing The Mentoring Landscape In An Online Biology Cure: An Examination Of Student And Graduate Teaching Assistant Perspectives And Outcomes, Karen Alejandra Santillan

Open Access Theses & Dissertations

Both undergraduate research experiences (UREs) and course-based undergraduate research experiences (CUREs) provide students with benefits and opportunities such as improving technical skills and making connections that provide resources. Where these two experiences differ is accessibility. Similar to their URE counterpart, CUREs entail mentorship on the part of the faculty/graduate teaching assistant (GTA) instructor (Dolan, 2016). There is general agreement that mentoring has many benefits for undergraduate STEM students, such as an improvement in retention rates, increased confidence and self-efficacy, and a more established sense of belonging and science identity (Dolan, 2016). CURE instructors often adopt the role of “mentor” in …