Digital Commons Network^™

Nivolumab Plus Ipilimumab Induce Hyper-Progression In Renal Medullary Carcinoma: Results Of A Phase Ii Trial And Preclinical Evidence, Melinda Soeung, Xinmiao Yan, Ciro Zanca, Jing Qian, Menuka Karki, Fei Duan, Hania Khan, Li Zhang, David H Peng, Mariah Williams, Rong He, Ziheng Chen, Luigi Perelli, Jianfeng Chen, Rebecca S Tidwell, Pankaj K Chauhan, Courtney N Le, Truong N A Lam, Nirjar Bhattacharya, Rutvi Shah, I-Lin Ho, Jason P Gay, Caroline C Carrillo, Ningping Feng, Kang Le, Guang Gao, Teresa L Perry, Faika Mseeh, Yongying Jiang, Quanyun A Xu, Niki Marie Zacharias, Rahul A Sheth, Tharakeswara K Bathala, Priya Rao, Najat C Daw, Durga N Tripathi, Cheryl L Walker, Mohammad M Mohammad, Jianhua Zhang, Guangchun Han, Yanshuo Chu, Ruiping Wang, Minghao Dang, Enyu Dai, Fuduan Peng, Yunhe Liu, Akshaya Jadhav, Wenhua Lang, Claudio A Arrechedera, Leticia Campos Clemente, Edwin R Parra, Hsinyi Lu, Cara L Haymaker, Ignacio I Wistuba, Andrew Futreal, Andrea Viale, Michael J Soth, Philip Jones, Joseph R Marszalek, Timothy Heffernan, Giulio F Draetta, Nizar M Tannir, Jianjun Gao, Linghua Wang, Giannicola Genovese, Pavlos Msaouel

Faculty, Staff and Students Publications

Therapeutic options for patients with renal medullary carcinoma (RMC) are limited. Here we report the results of a phase II clinical trial (NCT03274258) of anti-PD1 nivolumab plus anti-CTLA4 ipilimumab in patients with RMC, with objective response rate as primary outcome. Enrollment was halted for futility at a prespecified interim analysis as all 10 treated patients experienced rapid disease progression. 5/10 met radiological criteria for hyperprogression and median progression-free survival (secondary outcome) was 1.38 months (95% confidence interval: 1.28, 1.60). In a post-hoc single-cell RNA sequencing analysis, data from patients with RMC before and after nivolumab plus ipilimumab treatment indicated that …

Immunological Surveillance Against Cancer Across Mammals, Orsolya Vincze, Piotr Minias, Alexandre Corthay, Fernando Colchero, Jean-François Lemaître, Louise Maille, Tamás Malkócs, Justus Hagemann, Dalia A. Conde, Samuel Pavard, Antoine M. Dujon, Beata Ujvari, Frédéric Thomas, Amy M. Boddy, Carlo C. Maley, Damien Chevallier, Tuul Sepp, Thomas Pradeu, Mathieu Giraudeau

Presidential Fellows Articles and Research

Contrary to expectations based on their higher cell numbers, larger and longer-lived species do not face dramatically increased risk of cancer. This strongly suggests that evolution has fashioned natural cancer resistance mechanisms, yet our knowledge remains limited on what these mechanisms might be. The cancer immunological surveillance hypothesis, proposed by Burnet and Thomas in the 1950s, highlights immunity as a key factor determining species-specific cancer resistance. Here we address the original, evolutionary interpretation of this hypothesis by investigating the relationship between cancer mortality risk and markers of efficient antigen presentation. Our results show that the expansion of the MHC class …

Antifungal Effects Of Fatty Acids On The Growth Of Ophidiomyces Ophiodiicola In A Simulated Snake Skin Environment, Krupa S. Patel, Lizbeth Delarosa, Jacey Cardenas, Thalia Rodriguez, John Niedzwiecki

Science University Research Symposium (SURS)

Emerging infectious diseases have increasingly threatened wildlife populations worldwide, with devastating impacts observed in frogs, bats, and more recently, snakes. Snake fungal disease (SFD), caused by the pathogenic fungus Ophidiomyces ophiodiicola (Oo), currently poses a serious threat to snake populations across multiple regions. Infected snakes exhibit disrupted skin shedding, rough or scaly patches, crusty sores, and ulcers that compromise their health and survival. Although the mechanisms underlying transmission and susceptibility to SFD remain unclear, the snake cutaneous microbiome is known to act as a defensive barrier, mediating interactions between the host and invading pathogens. The lipid layer is a key …

Fungal Foes And Fatty Defenses: How Simulated Snake Skin Lipids Influence Ophidiomyces Ophiodiicola Growth, Thalia Rodriguez, Jacey Cardenas, Lizbeth Delarosa, Krupa Patel, John Niedzwiecki

Science University Research Symposium (SURS)

Emerging fungal diseases are a continuous threat to wildlife health as well as biodiversity. Fungal diseases, such as white nose syndrome in bats, can devastate populations by disrupting their ecosystems. Many other species around the world are affected by fungal diseases, such as amphibians, birds, and snakes. In more recent years, snake fungal disease (SFD) emerged due to the fungal pathogen Ophidiomyces ophiodiicola (O.o). Like Pseudogymnoascus destructans, the fungal pathogen responsible for white nose syndrome, O.o targets the skin which contains many fatty acids. Some studies have shown that fatty acids present in bat skin are able to inhibit fungal …

Surviving The Seasons: Climate And Time Effects On Native Songbirds, Essence Donaldson, Todd Hoskinson, John Niedzwiecki

Science University Research Symposium (SURS)

Bird populations across North America have declined sharply in recent decades due to habitat loss, climate change, and changes in food availability. As bird numbers fall, ecosystems lose essential pollinators, seed dispersers, and insect predators. Long-term monitoring of bird populations is vital for understanding how environmental changes influence their survival and abundance. This study examines capture data from a long-term bird banding station at Percy Warner Nature Center in Nashville, Tennessee, focusing on five native species: Northern Cardinal (NOCA), American Robin (AMRO), American Goldfinch (AMGO), Tufted Titmouse (TUTI), and Carolina Chickadee (CACH), from fall 1983 to fall 2023. We analyzed …

Investigating The Mechanisms Of Microbial Interactions Using A Model Cystic Fibrosis Polymicrobial Community, Bassam El Hafi

Dartmouth College Ph.D Dissertations

Cystic fibrosis (CF) airway microbial communities are complex ecosystems where interspecies interactions influence pathogen survival and disease progression. We leverage a CF-relevant in vitro four-species model composed of Pseudomonas aeruginosa, Staphylococcus aureus, Streptococcus sanguinis, and Prevotella melaninogenica, alongside a microbiome dataset with over 4,000 respiratory samples from publicly available sequencing data of CF patient samples, to explore the dynamics of microbial interactions in CF. On a broader scale, we performed microbial network analysis to examine how the latest modulator therapy, elexacaftor/tezacaftor/ivacaftor (ETI), might influence CF microbial communities. Our analysis revealed a reduction in node connections and …

Live-Cell Quantitative Monitoring Reveals Distinct, High-Affinity Gβγ Regulations Of Girk2 And Girk1/2 Channels, Reem Handklo-Jamal, Tal Keren Raifman, Boris Shalomov, Patrick Hofer, Uri Kahanovitch, Theres Friesacher, Galit Tabak, Vladimir Tsemakhovich, Haritha P Reddy, Orna Chomsky-Hecht, Debi Ranjan Tripathy, Kerstin Zuhlke, Carmen W Dessauer, Enno Klussmann, Yoni Haitin, Joel A Hirsch, Anna Stary-Weinzinger, Daniel Yakubovich, Nathan Dascal

Faculty, Staff and Student Publications

Gi/o protein-coupled receptors (GPCRs) inhibit cardiac and neuronal excitability via G protein-activated K+ channels (GIRK), assembled by combinations of GIRK1 - GIRK4 subunits. GIRKs are activated by direct binding of the Gβγ dimer of inhibitory Gi/o proteins. However, key aspects of this textbook signaling pathway remain debated. Recent studies suggested no Gi/o-GIRK pre-coupling and low (>250 µM) Gβγ-GIRK interaction affinity, contradicting earlier sub-µM estimates and implying low signaling efficiency. We show that Gγ prenylation, which mediates Gβγ membrane attachment required for GIRK activation, also contributes to the Gβγ-GIRK interaction, explaining the poor affinity obtained with non-prenylated Gβγ. Using quantitative …

Stiefel Md Anderson Oropharynx Cancer (Mda-Opc) Cohort: A Single-Institution, Prospective Longitudinal Outcomes Study, Amy Moreno, Ariana J Sahli, Faye Johnson, Xiaowen Sun, Carly Barbon, Waree Rinsurongkawong, Wenye Song, Flavie M Luciani, Han Liang, Jun Li, Wei Liu, J Jack Lee, S J Frank, Stephen Lai, Clifton Fuller, Katherine Hutcheson

Faculty, Staff and Student Publications

Purpose: The MD Anderson Oropharynx Cancer (MDA-OPC) cohort is a unique single-institution, prospective longitudinal cancer cohort. The cohort aims to enhance the therapeutic index of OPC management by supporting data needs for independent investigators to conduct rigorous observational studies examining exposures and factors associated with acute and late toxicities, cancer progression, recurrence, new malignancies and quality of life in OPC survivors.

Participants: A total of 1811 patients with OPC with a minimum follow-up of 6 months have been consented to our prospective registry between 18 March 2015 and 29 December 2023. Clinical and treatment (Tx) data are available on all …

Mycobacterium Chelonae Outbreak Investigation At A Quaternary Pediatric Hospital Following The Opening Of A Leed-Certified Critical Care Tower: Where Does Water Sustainability Intersect With Infection Control?, Andrea L Ankrum, Silvia M Caceres, Michael Torsell, Elaine Epperson, Vinicius Calado Nogueira De Moura, Jennifer J Gilick, Michael Strong, Qingyun Liu, Matthew J Strand, Rachel N Wilsey, Jennifer R Honda, Jane E Gross, Felicia A Scaggs-Huang

Faculty, Staff and Student Publications

Objective: Investigate the increased incidence of Mycobacterium chelonae positive respiratory cultures in hospitalized patients.

Design: Apply the Healthcare-Associated Links in Transmission of Nontuberculous Mycobacteria (HALT NTM) toolkit to an outbreak investigation of M. chelonae.

Setting: Quaternary-care pediatric hospital and medical center in the United States with a recently opened LEED-certified critical care tower.

Patients: Adult and pediatric patients with M. chelonae positive respiratory cultures between June 2022 and January 2024.

Methods: An epidemiological investigation involving clinical and laboratory practices, water management, building construction and renovation projects. Environmental sampling of air vents, water sources and endoscope reprocessing equipment was performed. M. …

Analysis Of A Deeply-Phenotyped Familial Hypercholesterolemia Cohort From Mexico Shows A Role For Both Rare And Common Alleles Across Known Dyslipidemia Genes And Reveals Structural Variation In A Novel Locus, Nicholas Katsanis, Niki Mourtzi, Consuelo D Quinto-Cortés, Alexandro J Martagon, Alexander G Ioannidis, Francisco M De La Vega, Jeff Gulcher, Ming Ta Michael Lee, Mohammad A Faghihi, Arturo Lopez-Pineda, Sonia Moreno-Grau, Daniel Mas Montserrat, Míriam Barrabés, David Bonet, Pavel Salazar Fernandez, Jeff Wall, Babak Moatamed, Roopa Mehta, Gabriela A Galan-Ramirez, Rafael Zubirán, Daniel Elias-Lopez, Teresa Tusié-Luna, Carlos A Aguilar-Salinas, Carlos D Bustamante

Faculty, Staff and Student Publications

Familial hypercholesterolemia (FH) is a genetic disorder driven in part by mutations in three genes that encode components of the cholesterol pathway: LDLR, APOB, and PCSK9. However, the majority of FH genetics has been performed in individuals of European descent. Here, we leveraged a cohort of 300 patients from the Mexican FH registry to understand how rare, high liability alleles and common variants might contribute to shaping individual risk. Using a combination of whole exome and of short- and long-read whole genome sequencing, we report three key findings. First, we observed that rare pathogenic point mutations and structural variants in …

Naphthalimide-Based Type-I Nano-Photosensitizers For Enhanced Antitumor Photodynamic Therapy: H2s Synergistically Regulates Pet And Self-Assembly, Huiyu Niu, Songnan Wang, Yang Liu, Nana Ma, Shuaiwei Cheng, Beidou Feng, Hyunsun Jeong, Yonggang Yang, Ge Wang, Tony D James, Juyoung Yoon, Jonathan L Sessler, Hua Zhang

Faculty, Staff and Student Publications

Photodynamic therapy (PDT) relies on a combination of light and photosensitizers (PSs) to achieve local control over cancerous lesions. However, it is subject to limitations, including tumor hypoxia, low tumor targeting, off‐target phototoxicity, and always‐on fluorescence. Here, we propose a design strategy for activated nano‐PSs (N‐PSs) to simultaneously overcome the limitations of PDT, wherein photoinduced electron transfer (PeT) is coupled with an endogenous H2S‐regulated self‐association process to promote Type‐I photochemical reactions. Using theoretical calculations, spectral analysis, and microscopic imaging, we verified the generation of self‐assembly and occurrence of PeT. And it was also shown that H2S could synergistically inhibit the …

A Geothermal Amoeba Sets A New Upper Temperature Limit For Eukaryotes, H Beryl Rappaport, Natalie A. Petek-Seoane, Tomáš Tyml, Felix Mikus, Kurt Labutti, Godwin Ani, Jessica K. Niblo, Ethan Macvicar, Rachel M. Shepherd, Ignacio De La Higuera, Samuel J. Lord, Kenneth M. Stedman, Multiple Additional Authors

Center for Life in Extreme Environments Publications

The study of temperature limits has transformed our knowledge of the boundaries of life but has been largely focused on bacteria and archaea. We isolated a novel geothermal amoeba, , that divides at 63°C (145.4°F), establishing a new record for the upper temperature limit across all eukaryotes. We demonstrated cellular proliferation with growth experiments and visualized mitosis expansion microscopy. Using high-temperature live-cell imaging, we quantified movement up to 64°C. We assembled the genome of and using comparative genomics found an enrichment of genes related to proteostasis, genome stability, and sensing the external environment. Taken together, our findings challenge the current …

The Effect Of Three Precooling Methods On Endurance Performance In Active Men, Bahman Mirzae, Mohammadreza E. Toloee, Omid Malekshahi, Victor Romano

International Journal of Exercise Science

International Journal of Exercise Science 18(6): 1410-1421, 2025. https://doi.org/10.70252/ERZX6867 The study aimed to compare the effect of three precooling techniques (internal, external, and combined) on the time to reach exhaustion in active men. Eight active men (23 ± 2 yrs; 178 ± 6 cm; 73 ± 11 kg) participated] in 4 exhaustive test sessions with a minimum power output of 40Wmax. Sessions included consumption of 7.5 grams of ice water with a temperature of -1 degree per kilogram of body weight, cold towels (4-6°C) used to cool the skin surface], a combination of ice water consumption and a towel cooling, …

2025 - The Sixth Annual Fall Symposium Of Student Scholars

Symposium of Student Scholars Program Books

The full program book from the Fall 2025 Symposium of Student Scholars, held in November 2025. Includes abstracts from the presentations and posters.

Fish-Spec: Fast Identification System For Handheld Spectroscopy And Species Classification, Mitchell Sueker, Nicholas Mackinnon, Gregory Bearman, Amanda Tabb, Diane Kim, Rosalee S. Hellberg, Alireza Akhbardeh, Hamid Reza Marateb, Jianwei Qin, Moon Kim, Fartash Vasefi, Hossein Kashani Zadeh

Food Science Faculty Articles and Research

Accurate fish species identification is critical to prevent mislabeling and fraud in the seafood industry. We present a handheld multi-mode point spectroscopy system that combines fluorescence (365 and 395 nm excitation) and reflectance measurements in the visible to near-infrared (∼350–900 nm) and short-wave infrared (∼900–1700 nm) regions for rapid, non-destructive classification of fish fillets. Tissue spectra were acquired at 25 positions on 68 fillets from 11 species, in both frozen and thawed states. Feature-level fusion across all four modes enabled higher classification accuracy than any single mode alone. A global machine-learning model classified all species with 85 ± 2.8 %, …

The Differential Effects Of Camp Mobilizing Agents On Tgf-Β-Induced Extracellular Matrix In Human Lung-Derived Fibroblasts: Insights Into Therapeutic Targets For Lung Fibrosis, Sarah Orfanos, Brian T. Deeney, Gaoyuan Cao, Nikhil Karmacharya, Anjani Ravi, Cynthia J. Koziol-White, Qi Yang, Rennolds S. Ostrom, Reynold A. Panettieri Jr.

Pharmacy Faculty Articles and Research

Background

Injury-repair responses typically induce tissue or organ scarring. Generally, cAMP-mobilizing agents inhibit the activation of fibroblasts and deposition of extracellular matrix. Some but not all cAMP-mobilizing agents inhibit fibrosis. Evidence suggests that inhaled treprostinil, a prostacyclin (IP) analog, increases intracellular cAMP levels [cAMP]I, and slows the decline in pulmonary function in patients with idiopathic pulmonary fibrosis (IPF). However, the molecular mechanisms by which cAMP-mobilizing agents, including treprostinil, alter the expression of matrix proteins in human lung fibroblasts (HLF) remain unclear. Unlike other Gαs -coupled receptors, we posit that the antifibrotic properties of treprostinil are driven by cAMP-mobilizing-dependent and -independent …

Harnessing Hyperspectral Imaging And Deep Learning For Terrestrial Habitat Mapping In Arid Landscapes: A Case Study In Saudi Arabia, Ali Elgendy, Hesham Morgan, Brandon Tran, Rejoice Thomas, Tamer Ismail, Yehya Kh. Shehadeh, Ahmed Elgharib, Ahmed Abdullah Al-Dughairi, Ali El Muburak, Khaled Allam Harhash, Hesham El-Askary

Mathematics, Physics, and Computer Science Faculty Articles and Research

Arid ecosystems remain under-mapped at actionable scales despite their ecological importance. Decision makers lack reliable, high-resolution habitat maps in drylands to prioritize protection and target restoration. This research integrates spaceborne hyperspectral imaging from the Environmental Mapping and Analysis Program (EnMAP) with deep learning semantic segmentation models to produce an updated level of habitat classification based on the International Union for Conservation of Nature (IUCN) for part of the Imam Turki bin Abdullah Royal Reserve, Saudi Arabia. Using ground control points and the full EnMAP spectral cube without band selection, U-Net and DeepLabV3+ architectures were each implemented with VGG19 and ResNet-101 …

Divergent Prefrontal Cortex Circuits Regulate Cued Food Seeking Under Distinct Metabolic Or Emotional States, Xu O Zhang, Guillermo Aquino-Miranda, Claire E Cho, Yongzhe Wang, Duy Hoang Ha, Nikita Elinson-Watson, Allen Dong, Caleb Kemere, Fabricio H Do-Monte

Faculty, Staff and Student Publications

Flexibly adjusting food-seeking behaviour in response to food-associated cues and internal states is crucial for animals' survival. However, the neural mechanisms that modulate cued food-seeking behaviour during varying metabolic (i.e., hungry vs. satiated) and emotional (i.e., safe vs. threatened) states remain elusive. Here, we show that the encoding of metabolic or threat states in projection-defined neurons in the prelimbic cortex (PL) mediates cued food-seeking responses in rats. Using microendoscopic imaging, we demonstrate that neural population dynamics in PL consistently represent food cues, task-relevant behaviours, and internal state changes by recruiting distinct subsets of cue-responsive neurons at each state. Single-unit recording …

Economic Convergence, Intragenerational Economic Mobility, And Inequality In A Native Amazonian Small-Scale Society Of Indigenous People In Bolivia, Ricardo Godoy, Jonathan Bauchet, Victoria Reyes-Garcia, Eduardo A. Undurraga

Department of Agricultural Economics Faculty Publications

Adult intragenerational mobility reflects society’s ability to reward effort and tame society-wide inequality. In developed economies, mobility is modest and correlates negatively with economic inequality. Little is known quantitatively from direct observations about long-term intragenerational mobility in small-scale societies of the Global South. To assess the external validity of findings about patterns of intragenerational mobility from developed economies, we use a yearly survey panel dataset (2002–2010) of adults from a society of native Amazonians (Tsimane’) in Bolivia practicing farming, fishing, hunting, and plant gathering. We estimate (a) convergence rates (or the speed of catch up) of adults in the bottom …

Renewal Of The Mind: Forgiveness Through The Lens Of Christian Faith And Neuroscience, Khelen Walsh

University Honors Theses

Within Christian theology, forgiveness is a foundational concept that is often understood as a divine command, a spiritual practice, and a path toward reconciliation and personal growth. Recent neuroscientific research further supports this viewpoint, providing data that shows forgiveness engages neural systems responsible for emotional regulation, empathy, moral reasoning, and perspective-taking. Through neuroplasticity, repeated acts of forgiveness reshape the brain, strengthen connections between prefrontal and limbic regions, reduce amygdala reactivity, and enhance emotional stability and cognitive flexibility. Although forgiveness offers many benefits, modern culture frequently distorts its meaning, framing it as a sign of weakness, gullibility, or a form of …

A Conversation With Dr. Shannon Jones Faculty Highlight, Paxton Mills

Osmosis Magazine

Dr. Shannon Jones, Senior Teaching Faculty in the Department of Biology, is a toxicology expert, teacher, and long-time mentor from Roper, North Carolina. With a PhD in Toxicology from the University of North Carolina at Chapel Hill, Dr. Jones came to the University of Richmond with a purpose: to transform the lives of her students.

Computer Problems? Must Have Been The Sun How Solar Particles And Cosmic Rays Affect The Future Of Computing, Ned Markham

Osmosis Magazine

Imagine playing your favorite video game, when suddenly, your character teleports to the top of the level. One may be quick to blame the software for faulty code, clueless that this error may have originated from an unlikely source: the sun. That’s right, during a speed run of Nintendo’s Super Mario 64, one stray cosmic ray flipped a single bit (a bit is the most basic unit of information inside a computer, storing one of only two possible values of 0 and 1), causing a streamer’s character to glitch in front of him and a live audience. This phenomenon, however, …

A Journey Into The Mysterious Quantum Realm, Kien Bui

Osmosis Magazine

Toward the end of the 18th century, many scientists believed that all the fundamental laws of physics had already been discovered. Falling apples obeyed Newton’s laws of motion, spinning compasses were explained by Maxwell’s unification of electricity and magnetism, and steam engines drove the first industrial revolution through the rise of thermodynamics. Lord Kelvin stated, “[t]here is nothing new to be discovered in physics now, all that remains is more and more precise measurement.” Only “two small clouds,” he warned, were the two remaining mysteries: black-body radiation and the theory of light. These small clouds, however, turned out to be …

From Sci-Fi To Reality: Could There Be Life On Mars?, Matea Šarkinović

Osmosis Magazine

Have you ever wondered: Are we alone in the universe? Well, scientists hope to answer the age-old question and they believe that Mars could hold the answer. The red planet has been identified as a potential home to life beyond Earth, and this article aims to explore what makes Mars such a strong candidate. Understanding the conditions on extraterrestrial objects is key to determining if our existence is a unique phenomenon or if we are the product of a recurring event that happens throughout the universe.

My Roman Empire: The Mystery Of Roman Concrete, Lilly Cashen

Osmosis Magazine

After the fall of an empire and millennia of conflict and decay, most structures crumble. Yet the monumental dome of the Pantheon, the towering ruins of the Colosseum, and the sprawling miles of aqueducts still stand today, two thousand years later, as testaments to Roman engineering brilliance. The survival of these ancient structures was made possible by one of Rome’s greatest innovations: Roman concrete, or opus caementicium.

True Silver: A Story Of Skin Coining With Silver In Traditional Asian Medical Practice, Trang Nguyen

Osmosis Magazine

Silver, one of the most precious metals on Earth, has captivated humans since prehistoric times for its natural shimmer, which has found its way into coins, jewelry, and ornaments (The Natural Sapphire Company, 2025). In traditional Asian medicine, silver’s significance extends beyond jewelry or currency; it is a key component in a practice called “cạo gió”, which involves releasing energy blockages and restoring balance to the body using a smooth metal tool to scrape the skin. Although it has been passed down through generations as a remedy for various ailments, a question remains: what makes silver the material of choice?

A Tragic Love Story Neanderthal-Human Interbreeding, Parth Patel

Osmosis Magazine

Humans moved northward when it became too hot and arid. Before that, we spent a few hundred thousand years evolving to the conditions of Africa (Hajdinjak et al., 2018). Our bones, genes, and skills were all honed to ensure survival in a particular climate, so when that climate began to change, the evolutionary traits that developed through years of mutations suddenly became deficient. It forced us to move in droves to Western Eurasia, where we found some comfort in the cooler weather (Slimak et al., 2024). We also found another species of human: the Neanderthal.

Spicomellus The Jurassic Enigma, Bryan Nam

Osmosis Magazine

Imagine stepping into a time machine and messing with the controls until you find someplace interesting to go. Your destination? Morocco, 165 million years ago. You arrive and look around at vast floodplains stretching far across the horizon; flat land cut through by mighty rivers. In the distance, you see something, a creature unlike any you’ve ever seen before. It looks straight out of a sci-fi movie. It seems almost like a reptilian tank, with huge spikes on its neck and hips. The dinosaur looks towards you, then turns away to look for food. You have just come face to …

Let’S Talk About Birds Baby: How Did Birds Evolve To Have Such Elaborate Courtship Rituals?, Lautaro Lo Prete

Osmosis Magazine

If you’ve ever watched a nature documentary featuring David Attenborough, you’ve definitely marveled at the eccentric and complex rituals of some bird’s courtship display. This behavior is a phenomenon among birds where males will often complete a ritualistic dance as a way to attract a female. But why go through all the hassle? What is the purpose of expending so much energy— all the while putting yourself at such a heightened risk of predation?

Does Free Food Lead To Less Food? Dependency Theory & The Ambiguous Effects Of Food Aid, Stevi Dugas

Osmosis Magazine

Dependency Theory, in the context of food aid, holds that food aid and subsequent increases in food supply disincentivize local agricultural production, resulting in local dependence on food aid for survival. But, is this actually the case? This article first explains the economic theory behind Dependency Theory, then examines why this theory may not connect to reality and some strategies for remedying the flaws of modern non-emergency food aid to ensure effective humanitarian aid.