Digital Commons Network^™

Independent Animal Chiropractic Practice: An Evidence-Based Argument For Autonomy Beyond Veterinary Supervision, Montana Adams

Undergraduate Honors Theses

Animal chiropractic is a growing form of conservative care used to improve mobility, reduce pain, and support neuromusculoskeletal function in animals. Despite evidence suggesting it is both effective and low risk, access remains limited due to inconsistent state regulations. Many jurisdictions require chiropractors to obtain veterinary supervision, referral, or licensure, even when they have completed specialized training and certification in animal chiropractic. This paper evaluates the effectiveness and safety of animal chiropractic while analyzing the impact of current regulatory policies. Research indicates that chiropractic care can improve mobility and reduce spinal conditions in animals when performed by trained professionals. However, …

Mitochondria As Primary Cause Of Neurodegeneration: Evaluating Causality Across Amyotrophic Lateral Sclerosis (Als), Alzheimer's, And Parkinson’S Diseases, Makenzie G. Johnson

Undergraduate Honors Theses

Neurodegenerative diseases like Alzheimer's Disease (AD), Parkinson’s Disease (PD) and Amyotrophic Lateral Sclerosis (ALS) have historically been explained through alternate hypotheses despite shared clinical hallmarks that lead to neuron loss. However, these varying explanations could not account for how disease onset begins among other individual issues. This thesis aims to show that mitochondrial dysfunction is a primary driver of neurodegeneration as well as a unifying mechanism shared between the three diseases. Evidence presented in this thesis will show that many issues can arise in mitochondria including issues with energy production, mitochondrial DNA (mtDNA), apoptosis activation, and calcium regulation. These issues …

Acute Responses To Low-Intensity Aerobic Exercise With Continuous And Intermittent Blood Flow Restriction, James Brown, Jakob D. Lauver, Timothy R. Rotarius, Justin P. Guilkey

Kinesiology

Introduction: This study examined muscular and cardiovascular responses to light-intensity aerobic exercise with different blood flow restriction (BFR) protocols. Methods: Ten males performed four protocols on the cycle ergometer: low-intensity exercise with no BFR (LIE), LIE with continuous BFR (CONT-BFR), LIE with intermittent BFR (INT-BFR), and high-intensity exercise (HIE). Each protocol consisted of five 2-min work intervals (INT) at 35% of peak work rate for LIE, CONT-BFR, and INT-BFR and 70% of peak work rate for HIE. During CONT-BFR, cuffs were inflated to 60% of arterial occlusion pressure (AOP) at the start of INT 1 and remained inflated until the …

Murder Of The Magic Mushroom Man, Andrea Florian, Alexa Cabral, Olivia Fawkes, Emily Gomez

SPARK Symposium Presentations

Rowan Tucker is an heirloom vegetable farmer that lives in Newbury, VT on an 80-acre farm. Most of the money in Rowan’s name was from selling psilocybin mushrooms that he disguised as payments under “crop-selling”. He was found dead presenting symptoms early that morning of confusion, hallucinations, vomiting, sweating, and extreme salivation. How did he get murdered? Who did it?

Evaluation And Enhancement Of Suspected Opioid Overdose Definitions In Emergency Medical Services Data Using Machine Learning With Natural Language Processing, Peter Rock, Svetla Slavova, Sharon L. Walsh, Julia Martin, Daniel R. Harris

Institute for Biomedical Informatics Faculty Publications

Background: Fatal and non-fatal drug overdoses have evolved into a critical public health crisis, with over a 50% increase in the rate of fatal drug overdose since 2019. Emergency Medical Services (EMS) data has advantages over traditional emergency department data, including timeliness and captured non-transport encounters. However, there is no consensus EMS definition for suspected opioid overdose (SOO), and currently implemented knowledge-based (KB) definition may miss ambiguous cases. Machine learning with natural language processing (ML-NLP) has the potential to enhance SOO identification.

Methods: Secondary data originated from an oversampled dataset of 2,327 weighted encounters from Kentucky State EMS data (2018–2022). …

Temporal Evolution Of Brain Inflammation In The Bilateral Common Carotid Artery Stenosis Model Of Chronic Cerebral Hypoperfusion, Makayla F. Cox, Jill M. Roberts, Ryan K. Shahidehpour, David L. Dornbos Iii, Adam D. Bachstetter

Neuroscience Faculty Publications

Chronic cerebral hypoperfusion is a major contributor to vascular cognitive impairment and dementia, primarily through its disruption of white matter integrity and promotion of neuroinflammatory cascades. The bilateral common carotid artery stenosis (BCAS) model has emerged as the predominant experimental approach for studying the effects of chronic cerebral hypoperfusion, particularly in aging-relevant contexts. This review synthesizes current knowledge of inflammatory responses in the BCAS model, with an emphasis on their temporal progression and functional consequences. We begin by outlining the clinical burden of hypoperfusion, the rationale for BCAS, and the hemodynamic phases it produces. We then examine early neurovascular unit …

Dim Light At Night Impacts Circadian Rhythms And Alzheimer’S Disease-Like Neuroinf Lammation And Neuropathology In Humanized App Saa Knock-In Mice, Marilyn J. Duncan, Margaret R. Hawkins, Leke Bytyqi, Haleigh R. Whitlock, Savannah M. Shepard, Makayla F. Cox, Esther G. Drinkard, Teresa Macheda, Kelly N. Roberts, Katharina Kohler, Mary-Claire Schmidt, Carrie E. Johnson, Sridhar Sunderam, Bruce F. O'Hara, Michael Paul Murphy, Adam D. Bachstetter

Neuroscience Faculty Publications

Artificial light at night (light pollution) is widespread but understudied in the context of Alzheimer’s disease (AD). Sleep and circadian disruption have been linked to amyloid-β (Aβ) accumulation and neuroinflammation, but whether dim light at night (dLAN) modifies these processes remains unclear. We tested whether chronic dLAN exposure (8 lux during the dark phase, 8 weeks) alters circadian rhythms, amyloid pathology, and neuroinflammation in 12–13 month-old humanized APP knock-in (KI) mice. hAPP^SAA KI mice, which develop plaques, were compared with hAPP^WT KI controls carrying only a humanized APP sequence. dLAN reduced circadian rhythm amplitude and stability while increasing …

Brain-Derived Extracellular Vesicles Potentially Mediate Crosstalk With Peripheral Organs In Neurodegenerative Diseases, Ramzi H. Hamdalla, Vibha B. Bhaskar, Changhai Tian

Toxicology and Cancer Biology Faculty Publications

Brain-Derived Extracellular vesicles (BDEVs) are emerging mediators of intra- and interorgan communication in neurodegenerative diseases (NDs) such as Alzheimer’s Disease (AD) and Parkinson’s Disease (PD). A growing body of evidence suggests that BDEVs play an important role in modulating intercellular communication within the central nervous system in the pathogenesis of many NDs. By transporting non-coding RNAs (e.g., miRNAs) and important pathological proteins, BDEVs also influence peripheral organs and contribute to the progression of disease in the central nervous system (CNS). This review extends the understanding of NDs beyond solely brain dysfunction and gives a novel framework for the progression of …

A Ubiquitous Organophosphate Flame Retardant Disrupts Energy And Glucose Homeostasis In Mice, Krystal M. Sewell, Kelly Oriakhi, Sara Y. Ngo Tenlep, Megan L. Weaver, Mansura Shahad Bawa, Se-Hyung Park, Shubh Saraswat, Xiaohua D. Zhang, Robert N. Helsley, Samir Softic, Cetewayo S. Rashid

Pharmacology and Nutritional Sciences Faculty Publications

Organophosphate flame retardants (OPFRs) are used in many consumer products, and their presence in our environment raises concerns about potential health dangers. In humans, exposure to OPFRs, such as tris(1,3-dichloro-2-propyl) phosphate (TDCPP) is associated with metabolic disorders such as obesity, hyperglycemia, and insulin resistance. Our current study seeks to determine how TDCPP exposure affects body composition, glucose homeostasis, and energy balance in a rodent model. C57Bl/6 J mice were divided into two weight-matched groups and fed purified low phytoestrogen diets containing either 0.1 % DMSO (control) or TDCPP 415 mg/kg resulting in an approximate exposure of 50 mg/kg/day. Both male …

Contribution Of Metabolism-Independent Glucose Sensing To Metabolic Homeostasis, Nadia Rashid, Kavaljit H. Chhabra

Pharmacology and Nutritional Sciences Faculty Publications

Glucose sensing and signaling are central to cellular metabolic machinery for the regulation of metabolic homeostasis. Glucose sensing has been almost always assumed to be coupled with glucose metabolism; however, recent findings have unraveled metabolism-independent sensing mechanisms. Here, we discuss whether glucose transporters (GLUTs) and sodium-glucose co-transporters (SGLTs) may also function as glucose sensors independent of their roles in transporting glucose. Moreover, we review the emerging roles of G protein-coupled receptors (GPCRs) in sensing glucose and, consequently, initiating its signaling pathways in a cell-specific manner. Altogether, this review offers insights into the newly identified glucose sensing mechanisms and highlights the …

Anatomical Atlas Of Kinase Responsiveness To Weight Gain: Adipose Depot Reprogramming In Diet-Induced Adiposity, Wang-Hsin Lee, Zachary A. Kipp, Sally N. Pauss, Genesee J. Martinez, Mei Xu, Terry D. Hinds, Jr.

Pharmacology and Nutritional Sciences Faculty Publications

Background/Objectives: Adipose tissue depots located at different anatomical sites exert differential functions in response to adiposity and glucose intolerance. These fat depots exhibit distinct metabolic signaling patterns that may influence pathological fat accumulation, thereby affecting the efficacy of anti-obesity interventions. Nonetheless, the mechanisms underpinning depot-specific signaling and pathway responsiveness remain insufficiently understood.

Methods: Kinase activity was characterized during the progression of adiposity across five adipose tissue depots in obese versus lean mice using the advanced PamGene kinome technology. Furthermore, kinase pathways in human preadipocytes and mouse 3T3-L1 preadipocytes were analyzed and compared with those in their differentiated, mature adipocytes. The …

Effects Of Rnai Of Ribophorin 1, Eukaryotic Translation Initiation Factor 2 Beta, And Peptidylprolyl Isomerase A In Acyrthosiphon Pisum, Brandon L. Kennemer

Master's Theses or Doctor of Nursing Practice

Three genes found in the Unfolded protein response, Ribophorin 1, Eukaryotic translation initiation factor 2 beta, and Peptidylprolyl isomerase A are thought to be potential targets for RNA Interference (RNAi) in Acyrthosiphon pisum.  Ribophorin 1 (RPN1) is a transmembrane glycoprotein that assists in anchoring ribosomes to the rough endoplasmic reticulum membrane.  It acts as a substrate-specific chaperone.  It facilitates N-glycosylation by delivering newly synthesized proteins to the oligosaccharyltransferase (OST) complex.  Eukaryotic translation initiation factor 2 beta (eIF2B) is a key component of the eIF2 heterotrimer that facilitates protein synthesis initiation by binding GTP and recruiting a specific transfer RNA to …

Buzzes Over Burrows: Bats And Black-Tailed Prairie Dogs In Western Kansas, Patrick L. Geyer

Master's Theses or Doctor of Nursing Practice

The native grasslands of the Great Plains and the organisms that inhabit them are threatened by the anthropogenic disturbance of land-use change; prairie dogs (Genus Cynomys) are one such example. These mammals are considered ecosystem engineers due to their behaviors that physically modify the areas they inhabit, directly affecting the resources available to surrounding organisms. Much research exists on established or potential relationships between black-tailed prairie dogs (Cynomys ludovicianus) and other taxa; until recently, one taxon group absent from mentions of an association with black-tailed prairie dogs was bats (Order Chiroptera). Results of acoustic studies in eastern …

Genomic Characterization Of A Novel Bloom-Forming Cyanobacterial Species From Western Kansas., Louisa Acquah

Master's Theses or Doctor of Nursing Practice

Harmful cyanobacterial blooms are a danger to freshwater systems, particularly in water limited regions such as western Kansas, yet the genetic identity and diversity of bloom-forming taxa in this region remain poorly characterized. In this study, I investigated a cyanobacterial bloom in Horsethief Reservoir (Kansas, USA) in summer 2024 with the aim of resolving the taxonomic identity and genomic features of the dominant organism. Bloom water samples were collected, and the dominant cyanobacterium was enriched and rendered nearly axenic through controlled cultivation and repeated subculturing. Preliminary 16S rRNA gene sequencing indicated affiliation with the genus Limnothrix, but with notable …

Exploring The Link Between Soil Microbes, And Land Use Through A One Health Lens, Yaw A. Antwi

Master's Theses or Doctor of Nursing Practice

The diversity of microbes within the soil plays an essential role in soil ecosystem

functioning. However, these microbes may also serve as environmental reservoirs for antibiotic resistance genes. The study examined the diversity of bacteria that are found in soil across Rural/Agricultural and Rural/Nonagricultural landscapes within some selected counties in Kansas and its associated antibiotic resistance genes taxa. A total of twenty-four soil samples was collected and analyzed using 16S rRNA gene amplicon sequencing which targeted the V3-V4 regions. Statistical analysis revealed that the alpha diversity metrics (Chao1 richness and Shannon evenness) showed no significant difference in microbial structure (p=0.693, …

The Synergy Between A Silver-Ruthenium Antimicrobial And Aminoglycosides Is Based On Severe Macromolecular Damage, Emmanuel P. Oladokun, Gracious Y. Donkor, Julius K. Narh, Grady D. Jacobson, Cade Ward, Patrick O. Tawiah, Lisa K. Polzer, Kevin A. Edwards, Kyle A. Floyd, Jan-Ulrik Dahl

Faculty Publications – Biological Sciences

The rise of multidrug-resistant (MDR) bacterial pathogens, including uropathogenic Escherichia coli (UPEC), highlights the urgent need for alternative treatment strategies to restore antibiotic efficacy. The silver-ruthenium antimicrobial AGXX exerts potent bactericidal effects through the production of reactive oxygen species (ROS); however, its potential synergy with antibiotics has not been thoroughly investigated. Here, we show that sublethal concentrations of AGXX strongly enhance aminoglycoside-mediated killing across a diverse panel of Gram-negative and Gram-positive MDR clinical isolates, including highly aminoglycoside-resistant strains. Combinational treatments significantly reduced the effective concentrations of gentamicin, tobramycin, kanamycin, and amikacin required to kill bacteria. Mechanistic analyses revealed that AGXX/aminoglycoside …

An Integrated Evaluation Of Trace Mineral Status, Regional Variation, And Supplementation Effects On Circulating Mineral And Reproductive Performance In American Plains Bison, Bailey M. Rodriguez

Electronic Theses and Dissertations

The continued expansion of the American Plains Bison (Bison bison) industry has increased the need for science-based nutritional recommendations tailored specifically to the species, due to limited species-specific research. Because trace minerals influence immune function, growth, and reproductive performance, establishing baseline mineral status and evaluating responses to supplementation are critical for advancing bison production and conservation efforts. This thesis integrates two complementary investigations to evaluate trace mineral status in American Plains bison at both regional and herd management levels. First, a herd level comparison evaluated the influence of differing mineral supplementation strategies on circulating mineral concentrations, herd performance, and reproductive …

Pollutant Load Reduction In Sarasota Bay, Florida (Usa): Target Development, Implementation, And Outcomes, David Tomasko, Mike Wessel, Jon Perry, Chris Anastasiou, Ryan Gandy

Gulf and Caribbean Research

Between 2006 and 2012, seagrass coverage across Sarasota Bay expanded by 1,108 ha, a 28% increase. During the subsequent years of 2012−2020, 830 ha of seagrass were lost, a 16% decline. In response to these findings, resource management efforts focused on determining the likely reason(s) why those 2 periods had such contrasting trends, to come up with strategies to reverse these losses. Based on results from the seagrass data, the 7—y period of 2006−2012 was designated a “reference period” and water quality data were compared against the subsequent 7—y designated “degraded period” of 2013−2019. Annual average chlorophyll-a (chl-a …

Bayesian Multivariate Modelling Of Lone Star (Amblyomma Americanum) Tick Life Stage Abundance And Temporal Trends To Inform Public Health Risk In Virginia, Thabo Lephoto, Henry Mwambi, Oliver Bodhlyera, Holly Gaff

Biological Sciences Faculty Publications

The increasing abundance of ticks poses a growing public health concern due to heightened human exposure to tick bites. The lone star tick (Amblyomma americanum: Ixodida: Ixodidae), a common human-biting species in the United States, has expanded its range in recent years. However, how its different life stages vary across time, habitats, and locations remains insufficiently understood. We analyzed tick abundance data collected in southeastern Virginia between 2009 and 2018, focusing on larval, nymphal, and adult life stages. A Bayesian multivariate modelling framework was used to examine seasonal patterns, habitat effects, spatial variation, and biological links between life stages. Two …

Left In The (Road) Dust: Analyzing Advanced Clean Cars Ii In California’S Disadvantaged Communities, Jj Hoffman

Pomona Senior Theses

Across the United States, air pollution disproportionately impacts minority groups. California’s Advanced Clean Cars II (ACC II) waiver was positioned to lead to significant environmental justice impacts, such as reductions in emissions and adverse health outcomes, by establishing stricter regulations for vehicle emissions and ensuring that 100 percent of new passenger vehicle sales are zero-emission by 2035. As the federal government recently nullified ACC II, pollution, and by extension health, could worsen, especially in disadvantaged communities. The thesis established several important relationships, including how disadvantaged communities experienced higher traffic, pollution, and worse health outcomes than non-disadvantaged communities. Though the results …

Feral Horses And Native Ungulates: Evaluating The Potential For Competition In Predator–Prey Communities Of Alberta’S Upper Foothills, Birch Gano

Graduate Student Theses, Dissertations, & Professional Papers

Feral herbivores are expanding in range and numbers globally, yet their community-level effects in ecosystems are poorly resolved. We evaluated whether feral horses reshape predator–prey–vegetation dynamics in Alberta’s Upper Foothills, Canada, through two pathways; i) potential exploitative competition for forage and ii) apparent competition via shared predators. We combined fecal DNA metabarcoding with remote wildlife cameras to quantify diets, spatiotemporal co-occurrence, and the role of horses in carnivore diet. We analyzed 241 ungulate scats (feral horses, elk, bighorn sheep, cattle, moose, and deer), 96 combined camera-years at 23 sites, and 190 carnivore scats (wolves, cougars, coyotes, bears) from 2023–2025. The …

Frame: Fast Reference-Based Ancestry Makeup Estimation Tool, Pramesh Shakya, Ardalan Naseri, Degui Zhi, Shaojie Zhang

Faculty, Staff and Student Publications

Motivation: The availability of large-scale genetic data presents a unique opportunity to study the genetic ancestries of individuals, which requires an efficient and scalable method. The existing global ancestry methods are accurate, but they cannot scale to large genetic datasets. Identity-by-descent (IBD) segments are DNA segments shared by individuals such that they are inherited from a common recent ancestor without recombination. These IBD segments, which reflect co-ancestry, provide an efficient alternative for inferring genetic ancestry.

Results: We introduced a reference-based global ancestry inference method called FRAME (Fast Reference-based Ancestry Makeup Estimation). FRAME utilizes partial local ancestry information estimated through IBD …

An Ensemble Classifier For Ordinal Outcomes In High-Dimensional Genomics Data, Heranga K. Rathnasekara, Sinjini Sikdar

Mathematics & Statistics Faculty Publications

Analysis of genomics data for predicting disease outcomes is a fast-growing field in medical research. There often exist categorical, specifically, ordinal outcomes that need to be predicted based on genomic profiles. This has led to recent development of some high-dimensional ordinal classification methods that can address the large dimensionality of the genomic covariate set. These high-dimensional ordinal models tend to vary widely in their performance depending on the data they are applied to and the evaluation criteria used. In this article, we outline an ensemble ordinal classifier that integrates different ordinal modeling approaches through bootstrap-based model evaluation, multi-metric performance assessment, …

Eeg Signatures Of Motor Development In Early Childhood: A Systematic Review, Sonia Khurana, Ashwini Kulkarni, Thomas C. Bulea, Hunter J. Bennett

Rehabilitation Sciences Faculty Publications

Background

Early identification of motor developmental disorders is limited due to lack of objective neural markers that characterize typical neurodevelopmental patterns. This systematic review interprets and synthesizes existing evidence to propose a framework of EEG signatures associated with motor development in children aged 0-5 years, which may help inform future benchmarks for early assessment and intervention.

Methods

Following PRISMA guidelines, we searched published and gray literature across five databases between 2000 and 2025 (registered protocol). Included studies examined EEG during task-based, resting-state, or sleep studies linked to motor milestones, task performance, or standardized motor assessments. Study quality was assessed using …

Characterization Of Phytoplankton-Excreted Metabolites Mediating Carbon Flux Through The Surface Ocean, Yuting Zhu, Hanna S. Anderson, Eli Salcedo, Samuel E. Miller, Krista Longnecker, Melissa C. Kido Soule, Sheean T. Haley, Gretchen J. Swarr, Rogier Braakman, Sonya T. Dyhrman, Elizabeth B. Kujawinski

Chemistry & Biochemistry Faculty Publications

The marine labile dissolved organic carbon (DOC) pool is a dynamic reservoir of thousands of molecules that cycles approximately one-quarter of Earth’s primary production within days to weeks. After excretion by phytoplankton and other microbes, metabolites are rapidly consumed, resulting in low standing concentrations (picomolar to low nanomolar). Despite the decades-long search for labile DOC sources and molecular identities, marine phytoplankton exometabolomes are not well characterized, largely due to difficulties in measuring small polar molecules in saline water. Here, we profiled the exometabolomes of six axenic phytoplankton species representing key functional groups including a diatom (Thalassiosira pseudonana CCMP1335), a …

Larval Genomics As A Viable, Fisheries-Independent Tool For Investigating Population Structure In Tropical Pacific Tunas, Jacob E. Jaskiel, Hannah E. Aichelman, Giulia Anderson, Louw Claassens, James E. Fifer, Christina M. Hernandez, Alexa K. Huzar, Joel K. Llopiz, Jan W. Witting, Sean P. Mullen, Randi D. Rotjan

Biological Sciences Faculty Publications

Understanding how dispersal, life history, and environmental variability shape genetic connectivity in the open ocean remains a central challenge in evolutionary biology. Highly migratory marine predators like tunas have traditionally been considered genetically homogeneous across ocean basins, yet emerging genomic evidence suggests that cryptic population structure can persist even in species with high gene flow and large effective population sizes. We used 2bRAD sequencing of 348 larval and subadult skipjack (Katsuwonus pelamis), yellowfin (Thunnus albacares), and bigeye tuna (T. obesus) collected from the central Pacific across 7 years of sampling to examine species boundaries, …

Lingnan Gardeners Newsletter (No. 77) = 彩園通訊 (第77期), Lingnan Gardeners, Centre For Cultural Research And Development, Lingnan University

Lingnan Gardeners Newsletter 嶺南彩園通訊

No abstract provided.

Rewwild: Reimagining Environmental And Wildlife Wellbeing Through Innovative Lawn Design, Morgan J. Sandau, Maiya G. Roelen, Katia E. Chavez, Lydia K. Niedermeyer

Undergraduate Theses, Professional Papers, and Capstone Artifacts

Manicured, monoculture lawns often dominate private land in urban areas for aesthetic organization. Colonialist roots are embedded in the history of turfgrass lawns and white-picket fences intended to suppress Indigenous knowledge and ways of caring for the diverse land around us. Private land misuse and homogenous lawns are not limited to the United States; the modern lawn contributes to biodiversity loss on a global scale. Humans are concentrated in cities across the world, and urban areas are known to have negative implications for wildlife and habitat, human health, and sustainable resource use. Management of private land in urban settings is …

Assessing Aerobic And Anaerobic Exercise As Therapies For Sarcopenia, Ella B. Farrer

Student Research Poster Presentations 2026

Sarcopenia is an age-related condition represented by progressive changes in muscle physiology that results in the loss of muscle mass and strength. The onset varies amongst individuals and can be influenced by various factors. On the cellular level, mitochondrial dysfunction and disruptions at neuromuscular junctions have been associated with the progression of sarcopenia. The condition ultimately reduces mobility, increases mortality, and hinders quality of life in older populations, necessitating an understanding of effective therapies.

Exercise was linked to symptom reduction of sarcopenia. Evidence indicated aerobic exercise and anaerobic exercise influence distinct molecular pathways involved in muscle physiology. Literature assessed the …

Microplastics Effect On Gut Microbiota, Victoria Rae Pellew

Student Research Poster Presentations 2026

Microplastics Effect on Gut Microbiota 

PELLEW, V, Misericordia University, 301 Lake Street, Dallas, PA, United States, 18612

Microplastics (MPs) are small plastic particles less than 5mm in size that are present throughout the environment and are commonly found in both food and water, making human exposure unavoidable. Ingestion occurs through consuming contaminated food, inhalation by breathing airborne particles, and dermal contact via phone cases or skin care products. Once absorbed into the body, MPs may influence human health by altering the gut microbiome.

Results from human fecal studies and in vitro models have shown that MPs can alter pathways associated …