Digital Commons Network^™

Impacts Of Biochar And Fe/Zn-Doped Biochar On The Degradation And Transformation Of Pfas In Wastewater Biosolids Compost, Chase Fry, R. Ryan Dupont, Joan Mclean

Spring Runoff Conference

Background

• >5.8 million dry metric tons of biosolids were produced in 2018.
• It is difficult & expensive to landfill all biosolids produced.
• Biosolids are increasingly used as an agricultural fertilizer and soil amendment.

Water Needs And Recovery Pathways For The Great Salt Lake, David Tarboton, Sarah Null, Bethany Neilson

Spring Runoff Conference

Main Points 

• Levels of GSL inherently fluctuate because of variability in precipitation and temperature that drive inflow and evaporation 
• Reductions in inflows due to water use are superimposed on this variability 
• Consistent delivery of conserved water offers the opportunity to shift the range of lake levels upwards reducing the occurrence of serious adverse effects and increasing the potential for healthy lake levels 
• Adding 250 thousand-acre ft/year reduces the occurrence of serious adverse effects from 61% to 28% over the long term 
• Adding 800 thousand-acre ft/year shifts the mean of variable lake levels to the lower end of the healthy lake …

Molecular Xenomonitoring For Early Detection Of West Nile Virus Circulation In New Jersey: A Field Validation Study, Viet-Linh Nguyen, Pratap Kafle

Graduate Student and Postdoctoral Fellow Symposium

West Nile virus (WNV) remains a persistent public health concern in New Jersey, yet current pooled-mosquito PCR surveillance often detects viral activity only after significant amplification, narrowing the window for timely intervention. Molecular xenomonitoring (MX), which is the detection of viral RNA in mosquito excreta or saliva deposited on honey-baited FTA cards, offers a non-destructive alternative that preserves nucleic acids at room temperature, passively captures signals from hundreds of mosquitoes per card, and has the potential to detect WNV circulation earlier than conventional surveillance by continuously sampling mosquito activity without the need for lethal collection. This project aims to (1) …

Microplastics As Physical Hubs Amplifying Antiobiotic Resistance Under Mixed-Contaminant Selection In Wastewater Systems, Liyuan Hou

Spring Runoff Conference

Microplastics (MPs) are tiny plastic particles within the range of (0.1 mm to 5 mm) in size

Bio 230 - Microbiology, Sarah Moroianu

Open Educational Resources

This open educational resource (OER) syllabus is designed for BIO 230: Microbiology at Lehman College, City University of New York (CUNY), a single-semester introductory microbiology course for non-biology majors such as Nursing, Dietetics, Health Education, and Physical Education. The course reviews microbial structure, metabolism, genetics, and microbial ecology, with applied emphasis on infectious disease, antimicrobial drugs, host immune defenses, and microbial diseases. The syllabus aligns course content with the freely available OpenStax Microbiology textbook (Parker et al., CC BY 4.0) and reflects accessibility best practices consistent with CUNY guidelines.

Great Salt Lake Basin Integrated Plan – Longterm Actions, Jake M. Serago

Spring Runoff Conference

GSL’s water level is in long-term decline. Water users face shortages and challenges. Increased temperatures, greater precipitation extremes and population changes are stressing water supplies in the basin. 84% of Utah residents think the Government is accountable for resolving issues facing GSL.

Mitochondrial Transfer And Induced Ros As A Therapeutic Strategy In Idh2-Mutant Chondrosarcoma, Vegas R. Bedder, Caleb Wyckoff, Chris Osgood, Gavin A. Vasquez, Michael Stacey

Knowledge and Creativity Expo

Chondrosarcoma (CS) are common bone cancers that produce cartilaginous tumors and are extremely refractive to chemo-and-radiation therapies, leaving very limited treatment options. They contain mutations in the isocitrate dehydrogenase genes, IDH1 or IDH2. Either IDH1 or IDH2 mutations are present in individual tumors, but not both. They both convert alphaketoglutarate (αKG) into the potent oncometabolite D-2-hydroxyglutarate (D2HG). D2HG can be transported from the tumors to cells of the tumor microenvironment (TME) where it can alter metabolic and epigenetic profiles in recipient cells. The process of α-KG to D2HG conversion occurs in the cytoplasm of IDH1 mutant cells, and in the …

Nexus Of Food Security Versus Armed Conflict In The Context Of Climate Change In Mali, Moussa Macalou, Youssouf Diabate, Abdoulaye Nientao, Adama B. Coulibaly

Professional Agricultural Workers Journal

The nexus between food security and armed conflict, with particular focus on developing countries, has been analyzed by a few studies in the literature. Every country under armed conflict is obligated to solve related food security issues. Therefore, the overall objective of this study was to analyze the nexus between households’ food security and armed conflicts in the context of climate change in Mali. To achieve this objective, first, the study used an ordinary least squares model to determine the factors influencing households’ food security. Second, it used an ordered logit model to determine the factors influencing armed conflict. Apart …

Artificial Intelligence In Mycology: A Systematic Review Of Species Identification, Biotechnological Assessment, And Explainable Deep Learning Methods, Fati̇h Eki̇nci̇, Mehmet Serdar Güzel, Ilgaz Akata

Turkish Journal of Botany

This review offers a comprehensive analysis of the expanding role of artificial intelligence (AI) in mycological research. It highlights how AI supports the identification of fungal taxa at both microscopic and macroscopic levels, facilitates the detection of toxic species, contributes to ecological mapping, aids in discovering new fungal bioproducts, and enhances precision agriculture practices. Advanced techniques such as convolutional neural networks, you only look once, U-shaped network (UNet), and residual network have demonstrated strong performance in classification, segmentation, and object detection tasks. Additionally, explainable AI (XAI) methods like gradient-weighted class activation mapping (Grad-CAM), local interpretable model-agnostic explanations (LIME), and SHapley …

Ethnobotanical Study Of Medicinal Plants Used By The Local Population In And Around Kozak Plateau (Bergama, İzmir, Türkiye), Şükrü Arasan, Hasan Yildirim

Turkish Journal of Botany

This research was conducted between 2020 and 2022 in 21 villages located on the Kozak Plateau and its surroundings, in the Bergama district of İzmir province, Türkiye. The main aim of the study is to document the medicinal uses of plants by the local population and to contribute to the preservation and transmission of ethnobotanical knowledge—passed down through generations— to future generations before it disappears. Interviews were conducted with 159 informants, and the traditional medicinal uses of 126 plant taxa belonging to 54 families were identified. Among these, the therapeutic uses of 37 taxa were recorded for the first time. …

Advancing The Alabama Black Belt Food Corridor: A Stakeholder-Driven Approach Through The Alabama Black Belt Food Systems Alliance, Kristin Woods, Tana Shealey

Professional Agricultural Workers Journal

A convergence of factors led to the need to bring together a diverse group of stakeholders to empower small-scale farmers in the Alabama Black Belt Region to safely scale up operations and access new markets. In the aftermath of the COVID-19 pandemic, there is renewed interest from government, producers, and consumers in strengthening local and regional food systems. This has led to a greater number of wholesale and retail market opportunities for farmers in the region. A newly formed Alabama Black Belt Food Systems Alliance (ABBFSA) endeavored to gather stakeholders to advance the Black Belt Food Corridor (BBFC) food system. …

Comparison Of Heavy Metal Accumulation In Soil And Wood Core Within Tallassee And Tuskegee, Alabama, Alicia R. Wilson, Brianna Smith, Latricia Miller, Rashidah Farid

Professional Agricultural Workers Journal

Heavy metals are natural components of the environment and can be relatively non-impactful in low concentrations. However, high concentrations of heavy metal toxicity can result in air, water, and soil contamination that adversely impacts environmental, human, and wildlife health. This study focuses on detecting the presence of heavy metals in soil, Loblolly Pine tree bark, and wood core samples from sites near a landfill in the Tallassee, Alabama, community and a post-agricultural site in Tuskegee, Alabama. It has been hypothesized that heavy metals are present in soil, tree bark, and the tree’s wood core from sampling sites. Samples were taken …

Impact Of In-Depth Adoption Of System Of Rice Intensification On Food Security Of Smallholder Farm Households In Mali, Moussa Macalou, John Baptist D. Jatoe

Professional Agricultural Workers Journal

The system of rice intensification (SRI) was implemented in Mali to boost rice productivity. The objectives of this paper are to identify the constraints faced by SRI adopters, estimate the food security index, and assess the impact of in-depth adoption of SRI on smallholder farm households’ food security. The study uses Kendall’s ranking to rank the six main constraints identified from the literature. The study uses the Household Food Insecurity Access Scale to estimate households’ food security index. Using primary data collected on rice farm households, the study combines the multivalued treatment effect inverse probability weighted regression adjustment and the …

Fecal Carbohydrate-Degrading Bacteria Are Associated With Reduced Incidence Of Lower Gastrointestinal Gvhd, Christopher Fan, Tomo Hayase, Chia-Chi Chang, Israel K Glover, Ivonne I Flores, Lauren K Mcdaniel, Miriam R Ortega, Christopher A Sanchez, Rawan K El-Himri, Alexandria N Brown, Jennifer L Karmouch, Mohamed A Jamal, Saira S Ahmed, Taylor M Halsey, Yimei Jin, Wen-Bin Tsai, Rishika Prasad, Altai Enkhbayar, Aqsa Mohammed, Maren Schmiester, Ashish Damania, Nadim J Ajami, Jennifer A Wargo, Christine B Peterson, Gabriela Rondon, Taha Al-Juhaishi, Amin M Alousi, Jeffrey J Molldrem, Richard E Champlin, Elizabeth J Shpall, Eric Martens, Cesar A Arias, Robert R Jenq, Eiko Hayase

Faculty, Staff and Student Publications

Lower gastrointestinal graft-versus-host disease (LGI-GVHD) carries morbidity and mortality for patients undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT), with critical contributions from the intestinal microbiome. In a retrospective cohort of metagenomic sequencing of stool from patients with allo-HSCT (N = 90), we found that a reduction in specific Parabacteroides and Bacteroides species around the time of engraftment contributes to LGI-GVHD risk. Given the known diverse carbohydrate-degrading functionality of these bacteria, we investigated gene abundances for carbohydrate-active enzymes (CAZymes) and found that Parabacteroides merdae, P distasonis, and Bacteroides ovatus abundances were significantly correlated with CAZymes in patients who did not develop …

Genome-Wide Crispr Screen Identifies A Cytokine-Enhancer Circuit Driving Hif-2Α Activation In Renal Cancer, Jun Fang, Jeremy M Simon, Tao Wang, Yunpeng Gao, Xianju Bi, Lianxin Hu, Chengheng Liao, Cheng Zhang, Yayoi Adachi, Jin Zhou, Hongyi Liu, Qian Liang, James A Nathan, Ram Mani, James Brugarolas, Qing Zhang

Faculty, Staff and Student Publications

Resistance to HIF-2α inhibitors such as Belzutifan underscores the need to better understand how HIF-2α is transcriptionally regulated in clear cell renal cell carcinoma (ccRCC). Here, we uncover a cytokine-driven enhancer mechanism that sustains HIF-2α expression through the JAK1-STAT3 signaling pathway. Using a genome-wide CRISPR screen in VHL-deficient ccRCC cells, we identified SOCS3 as a key negative regulator of HIF-2α. Mechanistically, loss of SOCS3 activates JAK1-STAT3 signaling, leading to the recruitment of STAT3 to distal enhancers upstream of EPAS1 that physically loop to its promoter to drive HIF-2α transcription. This cytokine-enhancer circuit was recapitulated in ccRCC patient samples and functionally …

The Do-It-Yourself Guide To Backyard Drip Irrigation, Jaydee Gunnell, Taun Beddes, Burdette Barker

All Current Publications

This guide promotes efficient backyard drip irrigation as a vital strategy for water conservation in Utah, the third-driest state in the U.S. It explains evapotranspiration (ET), drip system components, and provides formulas to calculate a plant’s water needs. The guide provides practical advice on converting traditional irrigation systems to drip systems, particularly in flower beds and around shrubs and trees. By implementing drip irrigation, homeowners can contribute to water conservation while enhancing the health of their landscapes.

Design Of Experiments Based Reversed-Phase High-Performance Liquid Chromatography Method For Estimation Of Metformin And Glimepiride In Combined Dosage Forms, Neela Manish Bhatia, Rachana Patil, Harinath More, Rutuja Dattatray Chougale

The Thai Journal of Pharmaceutical Sciences

Background: The present study aimed to systematically develop and validate a robust, rapid, and stability-indicating reversed-phase high-performance liquid chromatography (RP-HPLC) method for the simultaneous estimation of metformin and glimepiride in fixeddose combination tablets. Method development was guided by a design of experiments (DoE) approach using the Box-Behnken design (BBD) to ensure optimal analytical performance.
Materials and Methods: Chromatographic separation was achieved on a Cosmosil C18 column using an optimized mobile phase of acetonitrile and water (80:20, v/v) adjusted to pH 3.5. The flow rate was 1 mL/min, and detection was performed at 221 nm. The BBD approach systematically evaluated the …

Understanding The Coach Learning Environment In Formal, Field-Based Settings: A Self-Determination Theory Perspective, Jody L. Langdon, Shayla Snow

Journal of Coach Development

Grounded in self-determination theory (SDT), the purpose of this study was two-fold: 1) to evaluate the psychometric properties of SDT-related measures in a sample of coach learners, and 2) to examine the relationships between need satisfaction and frustration, coach motivation, and engagement in training sessions.. A total of 796 coaches participated in the study, completing surveys measuring basic psychological need satisfaction and frustration, coaching motivation, and engagement. Aside from confirming the validity and reliability of measures for use among coach learners, findings indicate that satisfaction of basic psychological needs positively correlated with intrinsic motivation and engagement, while frustration of these …

Best Integrated Writing Spring 2026 - Complete Edition, Wright State University School Of Humanities And Cultural Studies, Tracy Smith, Kristie Mckiernan

Best Integrated Writing

Best Integrated Writing includes excellent student writing from Integrated Writing courses taught at Wright State University.

Bacteriophage Therapy For Antibiotic-Resistant Infections, Shiva Pariyar

Best Integrated Writing

Pariyar examines bacteriophage therapy as a promising alternative to antibiotics for treating multidrug-resistant infections, highlighting its targeted mechanism, ability to disrupt biofilms, and synergy with antibiotics. While challenges such as regulation, immune response, and limited clinical trials remain, the study argues that advances in biotechnology and global collaboration position phage therapy as a future cornerstone in combating antimicrobial resistance.

Role Of Na⁺/K⁺-Atpase And Sodium–Calcium Exchanger In Digitoxin-Induced Cytotoxicity In Triple Negative Breast Cancer Cells, Alyson Sotomayor Quispe, Marilyn Odom Phd

SPARK Symposium Presentations

Triple Negative Breast Cancer (TNBC) is characterized by the absence of estrogen, progesterone, and HER2 receptors, limiting targeted treatment options. Digitoxin, a drug used to treat heart failure and atrial fibrillation through Na⁺/K⁺-ATPase inhibition, has demonstrated anticancer effects in TNBC cells, including apoptosis via the NF-κB pathway. This study investigates whether the Na⁺/K⁺-ATPase and sodium–calcium exchanger contribute to the mechanism of action of digitoxin in TNBC cells. We hypothesize that these transporters mediate digitoxin-induced cytotoxic effects. To test this, MDA-MB-468 cells were treated with digitoxin, and protein localization and expression were analyzed using immunofluorescence and Western blot. Digitoxin treatment resulted …

Tlr3 Mediated Type I Interferon Response In Mammalian Cell Defense Against Cryptosporidium Parvum Infection., Anjelica Matias

Biochemistry and Molecular Biology

Cryptosporidium parvum is a major cause of a diarrheal disease which affects many children in the USA as well as the rest of the world, yet the contribution of its double stranded RNA (dsRNA) viral symbiont, Cryspovirus (CSpV1) to host innate immunity remains unclear. This study investigated whether CSpV1 activates Toll Like Receptor 3 (TLR3) signaling pathways and downstream Interferon type I (IFN I) responses in mammalian intestinal epithelial cells. Confluent Human Ileocecal Colorectal Adenocarcinoma cells (HCT8) were exposed to CSpV1, and the expression levels of Tumor Necrosis Factor Receptor-Associated Factor 3 (TRAF3), Nuclear Factor-𝜅-light chain enhancer of activated B-cells …

Associations Between Reported Use Of Nutritional Labels And Calorie Intake In Us Adults: Findings From Nhanes 2017–2020, Ariana M. Chao, Nancy Greene, Alexandra Paul, Paule V. Joseph

College of Nursing Faculty Papers & Presentations

Objective: Caloric information is commonly displayed on nutritional fact labels and food menus. Yet evidence is limited on whether label use is associated with a reduced-calorie diet. This study examined the associations between the use of caloric information on nutritional facts and menu labels and daily caloric intake. Methods: We used data from adults in the National Health and Nutrition Examination Survey (NHANES) 2017–2020 to conduct a cross-sectional study. Calorie label use on nutritional labels and menus was assessed using the Flexible Consumer Behavior Survey telephone interview. Caloric intake was evaluated using the mean of two 24-h diet recalls implemented …

A Retrospective Analysis Of Taxane-Based Chemotherapy In Small Bowel Adenocarcinoma, Mir Lim, Nikhil Grandhi, Preksha Shah, Kanwal Raghav, Victoria Serpas, Maria Pia Morelli, Katrina Pedersen, Aparna Kalyan, Mohamed Salem, Ryan Huey, John Paul Shen, Huamin Wang, Hua Wang, Anjali Vinocha, Jane Thomas, Robert Wolff, Michael J Overman

Faculty, Staff and Student Publications

Background: Small bowel adenocarcinoma (SBA) is molecularly distinct from colorectal and gastric cancers, yet treatment typically parallels colorectal cancer. We evaluated the activity of taxane-based therapy in the largest SBA cohort to date.

Methods: We retrospectively reviewed SBA patients treated with taxane-based chemotherapy at MD Anderson Cancer Center from 1994-2024. Eligible patients had pathologic confirmation, received >1 treatment cycle, and had tumor response evaluation. Survival analyses were analyzed using Kaplan-Meier and Cox proportional hazard models.

Results: Seventy patients were identified. Median age was 57, and 59% were male. Primary sites were duodenum (44%), jejunum (34%), and Ileum (16%). Metastatic sites …

Key Elements Of Mission-Based Urban Agriculture In The United States Aimed At Addressing The Social Determinants Of Health, Jordan Losavio

LSU Doctoral Dissertations

Urban agriculture (UA) in the United States (U.S.) is increasingly positioned as a multi-domain strategy for addressing social determinants of health (SDOH), yet evidence is fragmented and often focused on participant outcomes rather than the organizational and environmental conditions that determine whether those benefits can be sustained, expanded, or maintained over time. This dissertation uses an exploratory sequential mixed-methods design to clarify (1) what SDOH outcomes are associated with UA in the peer-reviewed literature, (2) which internal and external factors leaders perceive as driving UA organizational success or failure, and (3) which factors predict comparative organizational functioning across a national …

Aquifer Characteristics And Groundwater Flow Modeling For Sustainable Water Resources Development And Planning Using Modflow Software In India, Ravi Sharma

AUIQ Complementary Biological System

MODFLOW is one of the most commonly used numerical models for simulating groundwater flow. Its structured data design and compatibility with GIS tools make it suitable for groundwater assessment and planning. Groundwater forms an important part of the hydrological cycle and occurs within the pore spaces of sedimentary rocks or within fractures in hard rock terrains. Although its distribution beneath the surface is not always uniform or predictable, it is still considered one of the cleanest, most accessible, and quickly available freshwater sources. Numerical groundwater models help convert complex subsurface processes into simplified relationships that describe flow behavior. Even though …

Contribution Of G4 Structure To Alzheimer’S Disease And Tau Pathology, Lena Michaela Kallweit

Electronic Theses and Dissertations

The occurrence of Alzheimer’s Disease (AD) is rapidly increasing as our global population ages. With the majority of therapeutic drugs in the last couple of decades failing clinical trials, new molecular targets are needed to combat the expected influx of new AD cases. AD pathogenesis is associated with abnormal protein aggregation, characterized in part by intracellular accumulation of hyperphosphorylated tau (p-tau) in neurofibrillary tangles (NFTs). RNA has been identified as a major non-proteinaceous component of NFTs and has been implicated as an active cofactor in tau aggregation and spread. Recent work has shown that aggregates from AD brains contain almost …

Pull Factors Of College Selection: The Role Of Club Sports In Student Enrollment Decisions, Brett A. Anderson, Sean Seiler, Thomas Baker

Journal of Issues in Intercollegiate Athletics

The relationship between club sports in intercollegiate athletics and their influence on student recruitment and retention remains underexplored within the broader participatory sport ecosystem. Guided by push–pull models of college selection, this study examines whether the availability of club sports functions as a meaningful pull factor in students’ decisions to enroll in and remain at an institution. Survey data were collected from 151 current undergraduate and graduate club sport athletes across the United States. Exploratory factor analysis identified a distinct Club Sports factor, demonstrating strong construct validity and internal consistency. Multiple regression analyses revealed that club sport availability was a …

Successful Treatment Of Juvenile Sterile Granulomatous Dermatitis And Lymphadenitis In A Pomeranian Aged 5 Months Using Topical Hydrocortisone Aceponate And Systemic Antibiotic, Nutjira Sawatmongkol, Sirada Tayayouth, Suttiwee Chermprapai

The Thai Journal of Veterinary Medicine

A 5-month-old intact male Pomeranian puppy was presented with a 2-week history of acutely swollen face, eyelids, lips, and muzzle. A physical examination revealed focal alopecia, folliculitis, and erythema on the muzzle, periocular, and perianal areas; crusts were also found around the muzzle. The puppy received monthly oral afoxolaner and milbemycin oxime. No ectoparasite was observed based on a trichogram test. Skin cytology revealed intracellular cocci and neutrophils. A skin biopsy taken from the muzzle revealed pyogranulomatous perifollicular dermatitis with epidermal spongiosis, intraepidermal pustules, and a superficial crust. This condition was diagnosed as juvenile cellulitis on the basis of age, …

Antibacterial Activity Of Sapium Ellipticum, Securidaca Longepedunculata, And Allophylus Africanus Against Drug-Resistant Pseudomonas Aeruginosa Isolates, Eleonora A. Mbare, Rose J. Masalu, Cyprian B. Mpinda

Tanzania Journal of Science

Pseudomonas aeruginosa poses a major clinical challenge due to its high levels of antibiotic resistance. This study evaluated the antibacterial activity of three medicinal plant extracts Allophylus africanus (leaves), Securidaca longepedunculata (root bark), and Sapium ellipticum (stem bark), against 30 drug-resistant P. aeruginosa isolates. Antibacterial screening was conducted using the agar well diffusion method, followed by determination of minimum inhibitory concentrations (MICs) via a 96-well microtiter plate assay. All three plant extracts demonstrated inhibitory activity against three resistant P. aeruginosa strains (gentamicin-resistant strains F4 and GR4RAU-AI, and ceftazidime-resistant strain 19-10), with inhibition zones of varying diameters. MIC values showed strain-specific …