Digital Commons Network^™

Examining Sustainable And Regenerative Viticultural Practices In The Rheinhessen Wine Region Of Germany, Claire Hoffmann

CISLA Senior Integrative Projects

No abstract provided.

Economy Smart Watch Fails To Accurately Monitor Blood Glucose Among Healthy Adults, Thinh Le Mr., Douglas Oberlin Dr., Adam Mohan Mr.

Undergraduate Research

Monitoring and maintenance of blood glucose (BG) concentrations is of critical importance to individuals with diabetes mellitus. However, this often requires multiple finger-sticks and a glucometer, or the use of a prescription continuous glucose monitor (CGM). Recently, some smart watches have become available which claim to non-invasively monitor BG. This should not be confused with watches that pair with CGMs. The purpose of this study was to assess whether the economy smart watches were capable of detecting BG changes among healthy individuals. Currently three participants have completed this study. Healthy young adults reported to the lab after a 4-6 hour …

Differences Between Media And Industry Professionals’ Views On Welfare Issues At Equine Racetracks In The United States, Olivia Burris

Honors College Theses

The objective of this project was to see if there was a difference in views between lay publications in the media and industry professionals regarding welfare issues occurring at equine racetracks. This study focused on the issues of drug usage and racing-related injuries in racehorses. This project examined current lay publications versus surveys of industry professionals discussing the specific welfare issues. These lay publications were reviewed and summarized for comparison to the industry professionals’ responses to the survey.

Frontier Healthscapes: Competing Narratives Of Disease, Environment, And Wellbeing In Early Minnesota, Aidan Reynolds

Geography Honors Projects

Across settler societies, health narratives were shaped by evolving tensions between lay and expert knowledge, frameworks of disease causation, and perceptions of the environment as both a source of health and a threat. In the decades following Euro-American settlement (1860-1900), Minnesota became a focal point for these debates, with its landscape fostering complex and competing narratives on health, wellbeing, and disease. This paper explores how public health discourse developed in Minnesota through the perspectives of institutions, the public, and economic interests. Combining environmental history with critical discourse analysis of archival materials, this study examines shifts within the Minnesota State Board …

Growing Pains: Assessing The Strategic Organizational Communication Approaches Of An Expanding Extension Organization, Anissa M. Mattox, Ashley Mcleod-Morin, Lauri Baker, Angela B. Lindsey

Journal of Human Sciences and Extension

As social structures evolve, strategic organizational communication (SOC) must also evolve for organizations to best meet the ever-changing needs of stakeholders. Assessing communications can guide the direction of an organization while also elevating the organization to the next level. For this study, researchers assessed the SOC strategy of the Extension Disaster Education Network (EDEN) through qualitative focus groups. Results of this study revealed internal communication and resources provided by the organization were perceived as positive communication approaches, while external communication and visibility were identified as negative communication approaches. Other Extension organizations could benefit from the results of this research as …

The Impact Of Maternal Age On The Expression Of Transgenerational Plasticity In Daphnia Pulicaria, Calvin Nguyen

2025 Spring Honors Capstone Projects - Archive

Transgenerational plasticity refers to heritable, non-genetic changes in phenotype that persist across multiple generations and can enhance offspring survivability in variable environments. In Daphnia, increasing maternal age has been associated with maladaptive plasticity. To investigate this relationship, six clones were collected from two Wisconsin lakes and acclimated to laboratory conditions through a common garden rearing process. For each clone, ten replicates were generated and evenly divided between young (clutches 2–4) and old (clutches 5–8) maternal age groups. Offspring were exposed to three dietary treatments for three experimental generations: one fed only green algae, one fed only cyanobacteria (a nutritionally …

Rnai Pathway Homeostasis Is Essential For Longevity In C. Elegans., Sejal Dulal

2025 Spring Honors Capstone Projects - Archive

RNA interference (RNAi) is a gene regulatory mechanism that is conserved across all animal species, including humans and the microscopic nematode, Caenorhabditis elegans. Many studies have identified the RNAi pathway factors and dissected the regulatory mechanisms of RNAi pathways, but there is little understanding of how the RNAi pathways themselves are regulated. Previously, Rogers and Phillips identified a feedback loop mediated by a pair of small RNA sensors, Sensor of siRNAs-1 (sosi-1) and eri-6[e-f], embedded within the genomic locus of a small RNA biogenesis factor, ERI-6/7. In this feedback motif, loss of small RNA-mediated silencing of …

A Comparative Analysis Of Small Nuclear Rna Sequences In Spinacia Oleracea, Arabidopsis Thaliana, And Homo Sapiens, Nhi T. Nguyen

2025 Spring Honors Capstone Projects - Archive

In eukaryotes, the structure and function of the Sm core and its associated small nuclear ribonucleoproteins (snRNPs) play a significant role in pre-mRNA splicing. These snRNPs exhibit a high degree of conservation. While plants also utilize alternative splicing, the conservation of plant snRNAs and other non-coding RNA such as snoRNA and scaRNA, which assemble the Sm core, remains largely unexplored. In this study, plant sequences were compared with human sequences using the multiple sequence alignment program Jalview to determine the conservation of snRNPs in other non-coding RNA. Sequences analysis showed that the Sm site in Spinacia oleracea and Arabidopsis thaliana …

Elucidating The Role Of Transposable Element Derived Gene, Dplg3, In Drosophila Melanogaster, Kaisy A. Martinez

2025 Spring Honors Capstone Projects - Archive

A big fraction of most eukaryotic genomes is comprised of transposable elements (TEs). TEs are mobile genetic sequences often causing deleterious effects as they increase in copy number. On rare occasions, TEs can undergo molecular domestication, where the TE proteins are co-opted by the host to serve cellular functions. In Drosophila melanogaster, domestication from PIF/Harbinger TEs has resulted in five Drosophila PIF-Like Genes (DPLG1-4 and 8). This study focuses on investigating the function of DPLG3. In DPLG3 knock out lines, DPLG3-KO, a fraction of the progeny shows an abnormal gonad phenotype. We sought to confirm …

Uncovering The Evolutionary Origins Of Neo-Sex Chromosomes In The Insect Family Membracidae, Mary Kumah

2025 Spring Honors Capstone Projects - Archive

This research explores the evolution of the neo-XX/XY sex chromosome system of Amblyophallus exaltatus, a treehopper insect in the family Membracidae. Neo-XX/XY sex chromosome systems can evolve from an XX/X0 sex chromosome system via fusion events between the X chromosome and an autosome. Although cytological work has indicated the presence of a neo-XX/XY system within A.exaltatus, the chromosomal identity of the fused autosome and the molecular drivers behind this chromosomal fusion remain poorly understood. By performing a coverage analysis with whole genome sequence data, the parts of the A.exaltatus genome that fused with the X chromosome will be better …

Genetic Influence Of Allelic Variation On The Phenotypic Variability Of Cognitive Outcomes In Individuals With Williams Syndrome., Marinie P. Joseph

Electronic Theses and Dissertations

Williams syndrome (WS) is caused by a rare microdeletion of 25 – 27 genes on chromosome 7q11.23, characterized by a distinctive cognitive profile with considerable phenotypic heterogeneity. However, the genetic factors underlying this phenotypic variability remain unclear. I explored two genetic mechanisms—parent-of-origin (PoO) effects and genome-wide polygenic variation, as measured by polygenic scores (PGSs)—to elucidate possible influences on cognitive variability in WS. The first study examined PoO effects on cognitive abilities in two overlapping samples of children with WS (N = 211, N = 251). PoO refers to which parental homolog of chromosome 7 contains the WS deletion. Despite …

Kinasefusiondb: An Integrative Knowledge Of Kinase Fusion Proteins In Multi-Scales, Himansu Kumar, Zikang Chen, Abayomi Adegunlehin, Loren Trowbridge, Leonardo Aguilar, Pora Kim

Faculty, Staff and Student Publications

Kinase fusion genes were the most targeted fusion gene group among multiple major cellular gene groups. Kinase inhibitors disrupt aberrant signaling cascades and inhibit tumor progression, yet the specific mechanisms of action of the U.S. Food and Drug Administration (FDA)-approved inhibitors in the context of kinase fusion oncoproteins remain largely unknown. This gap limits our ability to develop personalized therapies and next-generation kinase inhibitors. To address this, we developed a novel in silico pipeline for predicting 3D structures of kinase fusion proteins and performing structure-based virtual screening. This approach enables large-scale structural annotation and drug screening across pan-cancer kinase fusions. …

Ai Model For Predicting Asthma Prognosis In Children, Elham Sagheb, Chung-Il Wi, Katherine S King, Bhavani Singh Agnikula Kshatriya, Euijung Ryu, Hongfang Liu, Miguel A Park, Hee Yun Seol, Shauna M Overgaard, Deepak K Sharma, Young J Juhn, Sunghwan Sohn

Faculty, Staff and Student Publications

BACKGROUND: Childhood asthma often continues into adulthood, but some children experience remission. Utilizing electronic health records (EHRs) to predict asthma prognosis can aid health care providers and patients in developing effective prioritized care plans.

OBJECTIVE: We aimed to develop artificial intelligence (AI) models using various clinical variables extracted from EHRs to predict childhood asthma prognosis (remission vs no remission) in different age groups.

METHODS: We developed AI models utilizing patients' EHRs during the first 6, 9, or 12 years of their lives to predict their asthma prognosis status at ages 6 to 9, 9 to 12, or 12 to 15 …

Bmal1-Hif2a Heterodimer Modulates Circadian Variations Of Myocardial Injury, Wei Ruan, Tao Li, In Hyuk Bang, Jaewoong Lee, Wankun Deng, Xinxin Ma, Cong Luo, Fang Du, Seung-Hee Yoo, Boyun Kim, Jiwen Li, Xiaoyi Yuan, Katherine Figarella, Yu A An, Yin-Ying Wang, Yafen Liang, Matthew Deberge, Dongze Zhang, Zhen Zhou, Yanyu Wang, Joshua M Gorham, Jonathan G Seidman, Christine E Seidman, Sary F Aranki, Ragini Nair, Lei Li, Jagat Narula, Zhongming Zhao, Alemayehu A Gorfe, Jochen D Muehlschlegel, Kuang-Lei Tsai, Holger K Eltzschig

Faculty, Staff and Student Publications

Acute myocardial infarction is a leading cause of morbidity and mortality worldwide1. Clinical studies have shown that the severity of cardiac injury after myocardial infarction exhibits a circadian pattern, with larger infarcts and poorer outcomes in patients experiencing morning-onset events2–7. However, the molecular mechanisms underlying these diurnal variations remain unclear. Here we show that the core circadian transcription factor BMAL17–11 regulates circadian-dependent myocardial injury by forming a transcriptionally active heterodimer with a non-canonical partner—hypoxia-inducible factor 2 alpha (HIF2A)12–16—in a diurnal manner. To substantiate this finding, we determined …

First Specimen-Based Record Of Barbonymus Schwanefeldii (Bleeker, 1854) (Teleostei: Cyprinidae) From Laguna De Bay, Philippines, Kent Elson S. Sorgon, Marjorie Juliana L. Martinez, Andrei Justin F. So, Mariko Franccesca R. Aboganda, Jazreen Nicole G. Parungo, Aeris Johanne G. Poricallan, Keona Tiffany B. Prieto, Mellissa Jewel S. Magday, Alexa Charlize Dc Geronimo, Ma. Vianca Julia E. Anupol, Derreck O. De Leon

Biology Faculty Publications

The introduction of non-native fish species in the freshwater ecosystems of the Philippines presents a clear threat to native ichthyofauna, making verified reports of such introductions all the more critical. Through the examination of a collected specimen and anecdotes from fisherfolk and social media, we present here the first records of the occurrence of the tinfoil barb, Barbonymus schwanefeldii (Bleeker, 1854), in Laguna de Bay, Luzon Island, Philippines. This represents the addition of another non-native fish species in this lake, which is increasingly becoming dominated by non-native and invasive fishes that have been intentionally or accidentally introduced. Monitoring landed fish …

Toward The Application Of Natural Language Processing In Electronic Health Record Analysis For Taxonomy Development, Latoya Mcdonald

All Dissertations

Electronic health records (EHRs) are pivotal resources for nurse practice because they increase the timeliness and reliability of patient information at the point of care and support access by multiple healthcare providers and the individual patients themselves. However, it is widely recognized that data extraction from EHRs is challenging due to the variability in the language used in clinical care notes and the lack of standardized terminology across healthcare systems. The broad objective of this dissertation is to develop taxonomy-based classification models for nursing care by applying feature engineering approaches to EHRs that include nursing care of ostomy patients following …

Perspectives On Clinical Oncogenomics: Secondary Germline Variants Associated With Tumor Genomic Profiling In Community Cancer Care And Advanced Practitioner Oncogenomic Proficiency, Sarah Moncado

All Dissertations

Precision medicine in oncology is defined by the sequencing of tumor genomic variants that can be used to identify targeted treatment for patients. Secondary pathogenic and likely pathogenic germline variants (P/LPGVs) can incidentally be detected on tumor genomic profiling (TGP). With the rise in precision medicine over the past 15 years, secondary P/LPGVs on TGP have been an increasingly important clinical issue. However, there are factors that can lead to misidentification and underreporting of P/LPGVs. Germane to this clinical practice issue is healthcare provider oncogenomic literacy and proficiency.

A scoping review was conducted to evaluate the variability of the prevalence …

Investigation Into The Microbiome Of Blow Fly Eggs Using Microseqtm Id, Samantha S. Davis, Drusilla Sheridan, Jennifer Rosati

Undergraduate Research

There is little published research characterizing the microbiome associated with blow fly eggs and how they may affect the colonization behaviors of certain blow fly species. Once deposited, blow fly eggs are rapidly introduced to a diverse range of microorganisms, which can vary depending on the species of blow fly, the environment, and the decomposition stage of the substrate (Junqueira et al., 2017). Since blow flies are among the first insects to colonize decomposing remains, the microbial communities present on their eggs could serve as key indicators of the decomposition stage at the time of egg-laying, thus providing a potential …

Registration Of High Yield Conventional Soybean 'S17-2193' With Resistance To Multiple Diseases, Francia Seconde Ravelombola, Yi-Chen Lee, Donghun Lee, Caio C. Vieira, Alemu Mengistu, Lin Feng, Grover Shannon

Crop, Soil and Environmental Sciences Faculty Publications and Presentations

'S17-2193' (Reg. no. CV-565, PI 707954) is a high-yielding late maturity group IV (relative maturity of 4.7), conventional soybean [Glycine max (L.) Merr.] cultivar developed and released in 2022 by the University of Missouri Fisher Delta Research, Extension, and Education Center. S17-2193 was tested in over 88 environments (40 environments for preliminary, advanced, cooperative and uniform tests; and 48 environments for soybean state variety tests) from 2018 to 2021 in 10 states: Alabama, Arkansas, Illinois, Kansas, Kentucky, Louisiana, Mississippi, Missouri, North Carolina, and Tennessee. Results showed that S17-2193 was well adapted across the mid-South United States. This soybean cultivar has …

Cultural Health Benefits And Challenges Of Food Preparation And Consumption: A Comparative Study Of The United States, Italy, And Norway, Natalie G. Link

Undergraduate Honors Thesis Collection

This study aims to investigate the cultural health benefits and challenges associated with food preparation and consumption in the United States, Italy, and Norway, with a particular focus on citizens in lower socioeconomic levels. By examining the dietary habits, social structures, and health outcomes in these three countries, this research aims to uncover broader insights into the health status and well-being of their respective populations. The study will employ secondary data analysis approach examining existing research on cultural practices and social support systems. The findings of this research will contribute to a deeper understanding of the complex interplay between food …

A New Transition Metal Borate, Co6(B24O39(Oh)6(H2O) 6·2.21h2O, Synthesized Via A Mild Hydrothermal Synthesis, Alevtina Maksimova, Patrick Belt, Nilah Whitfield, Mark D. Smith, Gopabandhu Panigrahi, Gregory Morrison, Hans Conrad Zur Loye

Faculty Publications

A new transition metal borate hydrate, Co₆B₂₄O₃₉(OH)₆(H₂O)₆·2.21H₂O, was synthesized via a mild hydrothermal method using boric acid as the melt. The compound crystallizes in the trigonal space group P 3‾ with lattice parameters a = b = 13.17840(10) Å, c = 12.3287(2) Å, and a unit cell volume of 1854.27(4) ų (Z = 2). This borate hydrate crystallizes in a new structure type comprised of layers containing [BO3] trigonal planar units and [BO4] tetrahedra that are linked by CoO6 and Co(OH)2(H2O)4 octahedra via corner-sharing. The …

Whole-Genome Assembly And Annotation Of The Firecracker Penstemon (Penstemon Eatonii), David E. Jarvis, Mikel R. Stevens, Payton Carter, Ying Fei Lin, Kate E. Jaggi, Gabriela Jijon, Teal Kalt, Jouber Calixto, Samantha Standring, Kaitlin Torres, Kayla B. Stephensen, Hayley Mangelson, Noah H. Williams, Carolyn A. Wessinger, Peter J. Maughan, Paul B. Frandsen

Faculty Publications

The penstemons are ornamental annual flowering plants native to the Intermountain West and Rocky Mountains and commonly used for urban landscaping. Elite commercial penstemons are generally susceptible to abiotic stresses, including drought, root rot, cold, and high salinity. Firecracker penstemon (Penstemon eatonii), however, is much more tolerant to these stresses than most elite cultivars. Importantly, firecracker penstemon has been reported to hybridize with many other penstemons and therefore provides the opportunity to develop more tolerant elite cultivars through strategic crossing. To facilitate the study and utilization of firecracker penstemon, we sequenced and annotated the genome of a P. …

Nutrition, Sleep, And Training Habits Enhance Endurance Race Performance, Anna F. Breed

Honors Theses

In recent years, marathon and ultra-marathon participation has grown substantially. Past research has shown that a range of variables influence the performance of endurance athletes. This study included participants of the Forgotten Florida 50-mile and 100-mile race and the Chattanooga Erlanger Half-Marathon and Marathon. These athletes were questioned about their sleep, nutrition, and training habits implemented for the races they completed. The results show the significance of carbohydrate consumption throughout the race for energy maintenance and shortened race times. Also, it was found that hill repeats and tempo runs brought about more successful race times for the runners who implemented …

Assessing The Viability Of A Proposed Third-Party Reusable Foodware System: An Environmental And Economic Comparison, Margaret Milani

All Theses

The United States generates 73 million tons of plastic waste annually, with over 6% attributed to the restaurant industry. The EPA recommends that restaurants reduce their plastic waste by transitioning to reusable foodware items. Previous studies have shown that using a single reusable foodware item, such as a cup, can result in lower environmental impacts and greater economic benefits compared to single-use plastic alternatives. However, the upfront costs of purchasing reusables, commercial dishwashers, and other associated expenses remain significant barriers for restaurants, leading many to continue using single-use plastic foodware. This study aims to analyze and compare the environmental impacts …

Identifying Cognitive, Affective, And Developmental Mechanisms Linking Threat And Deprivation With Adolescent Psychopathology, Ekaterina Sadikova, David G. Weissman, Maya L. Rosen, Elise Robinson, Liliana J. Lengua, Margaret A. Sheridan, Henning Tiemeier, Katie A. Mclaughlin

Neuroscience: Faculty Publications

Background: The mechanisms linking early-life adversity with psychopathology over the life-course are complex. In this prospective study, we collectively examined cognitive, affective, and developmental mediators previously found to individually link childhood threat and deprivation experiences to adolescent psychopathology to identify the most potent mechanisms. Methods: Data came from a community sample of 227 children (mean child age 11.5 ± 0.5 years, 48.5% female) from the Seattle metro area with recruitment designed to reflect diversity in family income. Candidate mechanisms included self-rated pubertal development and task-measured attention bias to threat, emotion regulation, theory of mind, fear learning, inhibitory control, language ability, …

Registration Of 'R19c-1012': A High-Yielding Soybean Cultivar With Improved Flooding Tolerance At Early Vegetative Stages, Caio Canella Vieira, Rafael Marmo, C. Wu, Liliana Florez-Palacios, Andrea Acuna, D. Harrison, D. Rogers, Leandro Mozzoni, T. Roberts, J. F. Carlin, Travis Faske, F. Lin, G. Shannon, H. T. Nguyen

Crop, Soil and Environmental Sciences Faculty Publications and Presentations

'R19C-1012' (Reg. no. CV-564, PI 707837) is a high-yielding, conventional maturity group Mid-IV (Relative maturity 4.6) soybean [Glycine max (L.) Merr.] cultivar with improved flooding tolerance at V2-V4 vegetative growth stages. It was developed and released by the University of Arkansas System-Division of Agriculture Research & Extension Center in 2024. R19C-1012 has an indeterminate growth habit, purple flowers, gray pubescence, brown pods, and seed with an imperfect black hilum. From 2019 to 2023, R19C-1012 was evaluated across 40 irrigated environments, with an average grain yield of 4302 kg ha-1, representing 93% and 99% relative yield of the Xtend and non-Xtend …

Mechanisms Of Perennial Sorghum Resistance To Sugarcane Aphid Infestation, Esha Kaler

Department of Entomology: Dissertations, Theses, and Student Research

Sorghum, Sorghum bicolor (L.) Moench, the fifth most-grown cereal crop in the world, is a versatile crop, grown across different agro-ecological regions. Sorghum has numerous uses ranging from food and forage purposes to biofuel production. Sugarcane aphid (SCA; Melanaphis sacchari) is a major threat to sorghum production, accounting for 50% to 100% yield loss under heavy infestations. Perennial sorghum can be a sustainable and climate-resilient alternative to the current cereal farming systems. The development of perennial sorghum offers numerous benefits, such as reduced economic inputs, more carbon sequestration, better soil health, and sustainable yields. We employed host plant resistance …

Assessing The Implicit Prices Of Health And Wellness Product Attributes In Pet Food: A Hedonic Analysis Approach, Lonnie Hobbs Jr., Andrew Anderson

Agricultural Economics and Agribusiness Faculty Publications and Presentations

Here we examine product attributes present in dry dog food to show there exist potential price premiums and discounts associated with health and wellness attributes in dry dog food. The findings indicate price premiums are associated with attributes related to digestion and allergy care. Pricing discounts are found to be associated with immune support and dental attributes. The results of this study are anticipated to be a starting point for more sophisticated and dynamic analysis of pricing and willingness-to-pay studies in the pet food industry.

Exploring Factors That Contribute To Poverty Among Singleparent Households Headed By Latinas: A Qualitative Study, Jeffrey M. Balencia

Electronic Theses, Projects, and Dissertations

Background: Despite the new strategies and programs being developed and implemented, poverty still finds itself at a continuous increase yearly (Banovcinova et al., 2014). Families have been found to be the most susceptible group compared to everyone else due to the many factors they face that can affect them. By using the information provided by other articles, gaps identified is there are lack of studies on the factors that contribute to poverty among singleparent households headed by Latinas. Objective: This exploratory study aims to identify contributing factors to poverty among single-parent households headed by Latinas. Method: Qualitative data will be …

Impact Of Water Quality On The Nutritional And Phytochemical Properties Of Culinary Herbs, Genesis Arroyo

Electronic Theses, Projects, and Dissertations

Water quality significantly affected food safety, especially since contaminated water impacted crop growth and the nutrient composition of foods. Nitrates occur naturally in vegetables. However, when introduced into the food supply through water contamination, excessive levels disrupted the natural physiological processes of vegetables and other agricultural plants. These excessive levels eventually led to nutrient imbalances, decreased phytochemical concentrations, and potential health risks such as the formation of carcinogenic N-nitroso compounds in humans. This study evaluated the effects of nitrates on the nutritional outcomes of food crops, focusing on commonly used culinary herbs. While synthesizing findings from relevant peer-reviewed articles, I …