Digital Commons Network^™

Assessing Spatial Variability In Observed Infectious Disease Spread In A Prospective Time-Space Series, Chih-Chieh Wu, Chien-Hsiun Chen, Shann-Rong Wang, Sanjay Shete

Faculty, Staff and Student Publications

Most of the growing prospective analytic methods in space-time disease surveillance and intended functions of disease surveillance systems focus on earlier detection of disease outbreaks, disease clusters, or increased incidence. The spread of the virus such as SARS-CoV-2 has not been spatially and temporally uniform in an outbreak. With the identification of an infectious disease outbreak, recognizing and evaluating anomalies (excess and decline) of disease incidence spread at the time of occurrence during the course of an outbreak is a logical next step. We propose and formulate a hypergeometric probability model that investigates anomalies of infectious disease incidence spread at …

Post-Rt Head And Neck Dce-Mri: Association Between Mandibular Dose And Ve, Brandon Reber, Renjie He, Moamen R Abdelaal, Abdallah S R Mohamed, Samuel L Mulder, Laia Humbert Vidan, Clifton D Fuller, Stephen Y Lai, Kristy K Brock

Faculty, Staff and Student Publications

Background: Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is a functional imaging modality that can quantify tissue permeability and blood flow. Due to vasculature changes resulting from radiation therapy (RT), DCE-MRI quantitative parameters should be significantly different in regions receiving a high radiation dose compared to regions receiving a low radiation dose. This study sought to determine whether a significant difference exists in post-head-and-neck-cancer (HNC)-RT DCE-MRI quantitative parameters (Ktrans and ve) between regions of the mandible receiving a high radiation dose and regions of the mandible receiving a low radiation dose.

Methods: DCE-MRI was acquired from HNC subjects post-RT. The DCE-MRI …

A Needed Nomenclature For Nucleosomes, Michael-Christopher Keogh, Genevieve Almouzni, Andrew J Andrews, Karim-Jean Armache, Cheryl H Arrowsmith, Sung Hee Baek, Mark T Bedford, Emily Bernstein, Jacques Côté, Yael David, John M Denu, Beat Fierz, Benjamin A Garcia, Karen C Glass, Or Gozani, Kristian Helin, Steven Henikoff, Ole N Jensen, Steven Z Josefowicz, Neil L Kelleher, Tatiana G Kutateladze, Herbert H Lindner, Chao Lu, Karolin Luger, Parag Mallick, Catherine A Musselman, Tom W Muir, Ljiljana Paša-Tolić, Robert Schneider, Xiaobing Shi, Yang Shi, Simone Sidoli, Lloyd M Smith, Jessica K Tyler, Cynthia Wolberger, Jerry L Workman, Brian D Strahl, Nicolas L Young

Faculty, Staff and Student Publications

Histone post-translational modifications (PTMs) are crucial to eukaryotic genome regulation, with a range of reported functions and mechanisms of action. Though often studied individually, it has long been recognized that the modifications function by combinatorial synergy or antagonism. Interplay may involve PTMs on the same histone, within the same nucleosome (containing a histone octamer), or between nucleosomes in higher-order chromatin. Given this, the field must distinguish ever greater complexity, and the context in which it is studied, with brevity and precision. The proteoform was introduced to define individual forms of a protein by sequence and PTMs, followed by the nucleoform …

Green Human Resource Management, Employee Behavior, And Organizational Innovation: A Multi-Theoretic Pathway To Sustainable Competitiveness, Iwan Perwira, Hernita Hernita, Suardi Suardi, Andi Tenry Sose, Muhammad Azizurrohman

Journal of Environmental Science and Sustainable Development

As sustainability imperatives reshape global tourism, this study investigates how Green Human Resource Management (GHRM) practices can serve as strategic levers for driving sustainability performance and competitive advantage within Indonesia’s tourism sector. Amid rising environmental expectations and regulatory mandates, the research integrates Social Learning Theory, the Resource-Based View, and Institutional Theory to construct and test a model that links top management support, green organizational culture, and regulatory pressure to GHRM adoption. Using a cross-sectional survey of 510 employees and managers across eco-certified tourism firms in five Indonesian destinations, the study employed Partial Least Squares Structural Equation Modeling (PLS-SEM) to analyze …

A Mast Cell Receptor Mediates Post-Stroke Brain Inflammation Via A Dural-Brain Axis, Ruchita Kothari, Mostafa W Abdulrahim, Hyun Jong Oh, Daniel H Capuzzi, Collin B Kilgore, Sumil K Nair, Yaowu Zhang, Nathachit Limjunyawong, Sarbjit S Saini, Jennifer E Kim, Justin M Caplan, Fernanado L Gonzalez, Christopher M Jackson, Chetan Bettegowda, Judy Huang, Bhanu P Ganesh, Chunfeng Tan, Raymond C Koehler, Rafael J Tamargo, Louise D Mccullough, Risheng Xu, Xinzhong Dong

Faculty, Staff and Student Publications

The immune environment surrounding the brain plays a fundamental role in monitoring signs of injury. Insults, including ischemic stroke, can disrupt this balance and incite an exaggerated inflammatory response, yet the underlying mechanism remains unclear. Here, we show that the mast-cell-specific receptor Mrgprb2 regulates post-stroke brain inflammation from the meninges. Mrgprb2 causes meningeal mast cell degranulation after stroke, releasing immune mediators. This process recruits skull bone marrow neutrophils into the dura and further promotes neutrophil migration from the dura into the brain by cleaving the chemorepellent semaphorin 3a. We demonstrate that the human ortholog, MRGPRX2, is expressed in human meningeal …

Rare Variants In Prkci Cause Van Der Woude Syndrome And Other Features Of Peridermopathy, Kelsey Robinson, Sunil K Singh, Rachel B Walkup, Dorelle V Fawwal, Kendra M Vilfort, Amanda Koloskee, Azeez Fashina, Wasiu Lanre Adeyemo, Terri H Beaty, Azeez Butali, Carmen J Buxó, Wendy K Chung, David J Cutler, Michael P Epstein, Brooklynn Gasser, Lord J J Gowans, Jacqueline T Hecht, Anuj Mankad, Lina Moreno Uribe, Daryl A Scott, Gary M Shaw, Mary Ann Thomas, Seth M Weinberg, Eric C Liao, Harrison Brand, Mary L Marazita, Robert J Lipinski, Jeffrey C Murray, Robert A Cornell, Elizabeth J Leslie-Clarkson

Faculty, Staff and Student Publications

Van der Woude syndrome (VWS) is an autosomal dominant disorder characterized by lower lip pits and orofacial clefts (OFCs). With a prevalence of ∼1 in 35,000 live births, it is the most common form of syndromic clefting. Most VWS is attributed to variants in IRF6 (∼70%) or GRHL3 (∼5%), leaving up to 25% of individuals without a molecular diagnosis. Both IRF6 and GRHL3 function in a transcriptional regulatory network (TRN) governing differentiation of periderm, a single epithelial cell layer preventing pathological adhesions during palatogenesis. Periderm disruption can elicit a spectrum of phenotypes, including lip pits and OFCs, pterygia, and severe …

Preclinical Models Of Melanoma Leptomeningeal Disease To Assess Intrathecal Checkpoint Blockade, Renato A Guerrieri, Grant M Fischer, Jacob R Cortez, Barbara G Knighton, Debora A Ledesma, Courtney W Hudgens, Yimmy F Delcid, Qianghua Hu, Christian Y B Onana, Fernando C L Carapeto, Michael T Tezlaff, Jason T Huse, Patrick Hwu, Elizabeth M Burton, Isabella C Glitza Oliva, Michael A Davies, Sherise D Ferguson

Faculty, Staff and Student Publications

Leptomeningeal disease (LMD) is a subtype of central nervous system metastatic disease that is associated with poor patient outcomes and limited treatment options. There is an unmet need to develop preclinical models of LMD to expedite and improve the development of new therapeutics. Here, we describe the development of multiple orthotopic immunocompetent murine models of melanoma LMD, including their use to assess the efficacy of systemic and/or intrathecal immunotherapy. LMD was established by direct intrathecal injection of murine cell lines (B16-F10, BP, D4M, D4M-UV2, MC38-gp100, RMS, YUMM3.1, and YUMMER1.7) into the cisterna magna of C57BL/6 mice. Tumor take rate, distribution, …

Long-Term Outcomes In Flt3-Mutated Acute Myeloid Leukemia After Frontline Hypomethylating Agent, Venetoclax And A Flt3 Inhibitor, Nicholas J Short, Sanam Loghavi, Musa Yilmaz, Omer Karrar, Kunhwa Kim, Courtney D Dinardo, Tapan M Kadia, Manuel Maroun, Gautam Borthakur, Ghayas C Issa, Joseph Jabbour, Betul Oran, Elizabeth J Shpall, Uday Popat, Keyur P Patel, Mark Routbort, Marina Konopleva, Farhad Ravandi, Hagop Kantarjian, Naval Daver

Faculty, Staff and Student Publications

Triplet regimens with a hypomethylating agent, venetoclax and a FLT3 inhibitor yield high rates of response in newly diagnosed FLT3-mutated AML. However, the long-term outcomes and patterns of relapse with these triplet regimens are not well-established. In this retrospective analysis, 73 patients with newly diagnosed FLT3-mutated AML received a frontline FLT3 inhibitor-containing triplet regimen. The composite complete remission (CR) and CR with incomplete hematologic recovery (CRi) rate was 93%. Next-generation sequencing FLT3-ITD MRD negativity (sensitivity: 0.005%) was achieved in 60% of patients after cycle 2 and 90% after cycle 4. The estimated 3-year relapse-free survival (RFS) for FLT3-ITD-mutated and FLT3 …

Reversible Arginine Methylation Of Pi3kc2Α Controls Mitotic Spindle Dynamics, Yena Cho, Jee Won Hwang, Mark T Bedford, Dong Hee Na, Dae-Geun Song, Su-Nam Kim, Yong Kee Kim

Faculty, Staff and Student Publications

Microtubules, composed of αβ-tubulin dimers, undergo dynamic polymerization and are fundamental to cell structure and function. In the current study, we discovered that phosphatidylinositol 3-kinase class 2α (PI3KC2α) acts as a novel regulatory factor in microtubule dynamics. Specifically, asymmetric dimethylation of PI3KC2α at the R175 residue (R175me2a) by coactivator-associated arginine methyltransferase 1 (CARM1) enhances its interaction with α-tubulin, stabilizing microtubule assembly. Furthermore, lysine Demethylase 4 A (KDM4A) serves as an arginine demethylase for PI3KC2α R175me2a. During mitosis, protein kinase C (PKC)-mediated phosphorylation of KDM4A results in its dissociation from PI3KC2α, preventing demethylation and increasing R175me2a levels. This facilitates spindle formation …

Fisheries Research Report No. 354: Recreational Fishing For Abalone In Western Australia In 2024/2025 - Estimates Of Participation, Effort And Catch, Claire B. Smallwood, Karina L. Ryan, Lachlan W. Strain

Fisheries Research Reports

The Western Australian Recreational Abalone Fishery (RAF) operates in shallow coastal waters as a hand collection fishery while wading or diving. Three species of abalone are allowed to be caught. Roe’s abalone (Haliotis roei) are generally collected while wading from the shore in accessible nearshore reef complexes along the West and South Coast Bioregions. Greenlip abalone (H. laevigata) and Brownlip abalone (H. conicopora) are collected while wading (including snorkelling and freediving) and diving (using compressed air) predominantly along the South Coast Bioregion.

Recreational fishing for the three abalone species is licensed and highly regulated, especially in the Western Zone (which …

Nebline, October 2025

NEBLINE Newsletter Archive from Nebraska Extension in Lancaster County

Contents

4-H super fair helps youth become beyond ready

What's popping? by Natalie Sehi

Recipes of the month, by Kayla Colgrove: Fish bait snack mix, kicked up popcorn, and cinnamon crunch snack mix

Are your trees for the next storm? by Rachel Anderson

Garden guide: Things to do this month by Mary Jane Frogge

GRO Big Red virtual learning series

Composting demonstration

Promoting language development in young children by Hayley Jackson

Tip sheet for harvest 2025 by John Nelson

Rogers Memorial Day farm field day, September 2025

Heart of 4-H volunteer award: Rachel Wells

Join 4-H to become beyond ready …

El Contexto Socioambiental De Los Resultados De Salud Materno-Infantil: Pasantía En El Hospital Simplemente Evita, González Catán, Athmika Krishnan

Argentina: Public Health in Urban Environments

La Matanza, especialmente el área de González Catán es una de las zonas más pobres en la provincia de Buenos Aires. Este portafolio investiga cómo el contexto socioambiental de un centro de cuidado público como el Hospital Simplemente Evita se manifiesta tanto a través del perfil de la paciente como las capacidades del hospital, en la recuperación de la enfermedad y la reforma social para resultados de salud materno-infantil.

Creating Intergenerational Connections: A Multilevel Approach For Enriching Lives And Addressing Vital Community Issues, Matthew S. Kaplan, Nancy Z. Henkin

Journal of Human Sciences and Extension

This article presents an overview of intergenerational programs and practices as an interdisciplinary field of inquiry and practice that fosters open communication, support, and civic engagement across generations. Numerous examples of how intergenerational programs and practices harness age diversity to improve the human condition are presented. This includes initiatives to promote healthier lifestyles, reduce social isolation and loneliness, strengthen families, enrich education and lifelong learning, enhance community quality of life, and transmit cherished cultural traditions and values. This article highlights Extension’s longstanding contributions to intergenerational programming, showcasing notable examples across program areas and exploring opportunities for deeper engagement, co-leadership, and …

Mhc Gene Analysis And Immune Variation In Lepidodactylus Lugubris (The Mourning Gecko), Helen T. Vu

2025 Fall Honors Capstones Projects - Archive

The major histocompatibility complex (MHC) plays a central role in vertebrate immune defense by enabling pathogen recognition and initiating adaptive immune responses. While MHC diversity has been extensively studied in sexually reproducing species, comparatively little is known about its evolution in asexual lineages. The parthenogenetic gecko Lepidodactylus lugubris provides a unique opportunity to investigate how clonality and hybrid origins influence immune gene diversity. By leveraging whole-genome data, this study overcomes the limitations of previous transcriptome-based analyses and provides a more comprehensive view of MHC diversity in a clonal vertebrate. As the first step towards understanding MHC evolution in parthenogenetic lizards, …

Investigation Of Metals And Incidental Nanomaterials In Wildland-Urban Interface Fire Ashes And Their Impacts On Marine Phytoplankton, Talal Abdullah Alshehri

Theses and Dissertations

Wildfires are natural processes that have played a vital role in ecosystems for millions of years. However, with increasing anthropogenic activities and climate change, wildfires' frequency and intensity have increased. A wildfire is an uncontrolled fire that burns forests, grasses, and savannas. In addition to vegetation combustible materials, wildfire burn structure items such as homes, stores, and storage sheds in areas where the transition zone between urban and wildland is defined as the wildland-urban interface (WUI). Moreover, wildfires in WUI can burn vehicles, including automobiles, tractors, and boats on trails. Recently, there have been concerns regarding the metals, metalloids, and …

U-Shaped Relationship Between White Blood Cell Counts And Incident Hypertension In Military Young Adults: The Chief Study, 2014–2020, Kun-Zhe Tsai, Chia-Wei Hong, Yun-Chen Chang, Wei-Chun Huang, Xuemei Sui, Carl J. Lavie, Gen-Min Lin

Faculty Publications

Background

Systemic low-grade inflammation, which is characterized by increased counts of blood leukocytes (white blood cells, WBCs), can lead to hypertension, while reduced WBC counts caused by the use of some substances, e.g., alcohol, can also lead to hypertension. However, there have been no studies on the association between WBC counts and the risk of hypertension in young adults.

Methods

This cohort study conducted in Taiwan included a total of 2351 military personnel who were aged 18–39 years, were free of baseline hypertension and were followed up for incident hypertension from 2014 to the end of 2020. Resting blood pressure …

Characterization Of Mannosidases (Man) In Tetrahymena Thermophila Using Bioinformatics Tools, Cynthia Wen

Publications and Research

Mannosidases are a type of glycoside hydrolase (glycosidase) that facilitate the hydrolysis of glycosidic bonds in mannose-containing polysaccharides and glycans, including those found in glycoproteins. Their main role is to cleave specific linkages involving D-mannose residues, effectively trimming or degrading mannose-rich oligosaccharides. These enzymes are crucial in N-glycosylation pathways, which are essential for proper protein folding, glycoprotein maturation, and the regulation of carbohydrate metabolism in eukaryotic cells.

There are two main types of mannosidases: alpha-mannosidases and beta-mannosidases. In humans, several of these enzymes exist, including those found in the endoplasmic reticulum (alpha-mannosidase I), those in the Golgi apparatus (alpha-mannosidase II), …

Adipose Tissue Estrogen Receptor-Alpha Overexpression Ameliorates High-Fat Diet–Induced Adipose Tissue Inflammation, Marion C. Hope, Christian A. Unger, M. Chase Kettering, Cassidy E. Socia, Ahmed K. Aladhami, Barton C. Rice, Darya S. Niamira, Ben P. Wiznitzer, Diego Altomare Ph.D., William E. Cotham, Reilly T. Enos

Faculty Publications

Context

We created an innovative mouse model that enables inducible overexpression of estrogen receptor-alpha (ERα), specifically in adipose tissue (Adipo-ERα↑). Objective

We aimed to investigate how elevated Adipo-ERα↑ influences the development of high-fat diet (HFD)-induced obesity in both male and female mice. Methods

Male and female Adipo-ERα↑ mice and littermate controls were fed a low-fat diet (LFD) or HFD for 13 weeks. Adipo-ERα↑ was induced at the initiation of dietary treatment. Body morphology and composition, hepatic lipid accumulation, glucose tolerance, fasting insulin concentrations, and adipose tissue mRNA profiling were assessed. Liquid chromatography–mass spectrometry was used to determine circulating and adipose …

Role Of Growth Factors In The Pathogenesis Of Systemic-Sclerosis-Associated Fibrosis, Fabian A. Mendoza, Sonsoles Piera-Velazquez, Sergio A. Jimenez

Jefferson Institute of Molecular Medicine Papers and Presentations

Systemic Sclerosis (SSc) is a systemic autoimmune disease of unknown etiology characterized by a severe fibroproliferative vasculopathy and frequently progressive cutaneous and internal organ fibrosis. The small-vessel vasculopathy and the tissue fibrotic alterations are responsible for the most serious clinical and pathological manifestations of the disease and for its high mortality. Despite the high severity and frequent mortality, there are currently no optimal therapeutic approaches for SSc, and its complex pathogenesis has not been fully elucidated. Numerous studies have suggested that growth factors and related regulatory macromolecules released from inflammatory and other cells present in the affected tissues play a …

Community Partnerships To Address Social Determinants Of Health Among Older Adults, Cory Bolkan, Raven Weaver, Cheryl Eschbach, Erik Geissal, Breanne Wise-Swanson

Journal of Human Sciences and Extension

Focusing on social determinants of health (SDOH) among older adults is key to addressing health disparities, maintaining independence in their homes/communities, improving health outcomes, and avoiding high-cost institutional care. While primary care settings are equipped to meet older adults’ physical health needs, the network of Area Agencies on Aging (AAA) is designed to meet social needs (e.g., transportation, nutrition, caregiver support). Yet, cross-sector community partnerships between AAAs and primary care are rare. This article shares an evaluation of one such partnership, where SDOH screenings were routinely implemented in primary care, yielding social prescribing and direct referral to AAA’s support services. …

Pentanary And Hexanary Alkali Lanthanide Germanates Grown From Lanthanide Rich Flux Growth Reactions, Gregory Morrison, K. Pilar Zamorano, Virginia G. Jones, Ethan N. Adams, Hans Conrad Zur Loye

Faculty Publications

Single crystals of five compounds of a new structure type, the K3Nd52Ge12O100F7 type, were grown from lanthanide rich reactions using a KF/KCl flux: K3Ln52Ge12O100F7 (Ln = Nd, Eu), K3Ln52Ge12O100+δF7-δ (Ln = Pr, Tb), and K3Ca0.872Nd51.128Ge12O99.128F7.872. The five compounds crystallize in the cubic space group I-43d with lattice parameter 22.0350(2) Å for K3Nd52Ge12O100F7. The structure consists of a 3D checkerboard of LnX8, LnX7, LnX6, and GeO4 polyhedra, where X = O/F, and can be conceptually derived from the fluorite structure. K3Eu52Ge12O100F7 exhibits the fluorescence typical of Eu³⁺.

Zero Textbook Cost Syllabus For Env 3070 (Agroecology), Benjamin Iuliano

Open Educational Resources

Our relationships with the food we eat are deeply personal, but also connect us to a wide array of people, plants, animals, and landscapes around the world. Encompassing a diversity of scholarly approaches, the field of agroecology seeks to understand the interactions among these components, draw attention to the consequences of our present industrial food system, and create the conditions for more sustainable and just futures. In this course, students will learn about the science, practice, and social movement of agroecology through lectures, course discussions, field trips, and hands-on activities.

Way Kambas National Park: The Human-Wildlife Conflict Success Story Still In Need Of Improvement, Eleanor Lefkowicz

Indonesia: Arts, Religion, and Social Change

This paper investigates the negative interactions between humans and animals in Way Kambas National Park of Sumatra, Indonesia, and the prevention and mitigation tactics the community utilizes. The numerous villages surrounding the National Park suffer from elephant activity damaging their farms, while the elephants are frequently harmed by poaching within the park. Participate observations and interviews concluded that the Way Kambas community responds to human-wildlife conflict with a collaborative effort by locals, government park police, and non-governmental organizations to both deter elephant presence outside of the park and poaching activity within the park, as well as to mitigate the negative …

The Imperative Of Regeneration: Exploring The Dimensions Of Tourism And Agriculture In Bali, Ava Whitney

Indonesia: Arts, Religion, and Social Change

This research centers on the impacts of mass tourism, development, and modernization on the landscape and culture of Bali and investigates regenerative alternatives in agriculture and tourism. Regenerative thinking offers a vision of travel and subsistence that preserves the ecology of the landscape and the integrity of Balinese culture. Organic farming and permaculture principles are traditional agricultural practices in Bali that have existed for generations, imbued with the Tri Hita Karana philosophy of Balinese Hinduism. Agriculture is a facet of Traditional Ecological Knowledge (TEK) that transmits ecological and cultural wisdom to future generations about how to relate to the natural …

Lingnan Gardeners Newsletter (No. 76) = 彩園通訊 (第76期), Lingnan Gardeners, Centre For Cultural Research And Development, Lingnan University

Lingnan Gardeners Newsletter 嶺南彩園通訊

No abstract provided.

Machine Learning-Based Optimization Of Alginate, Guar Gum, And Pectin-Based Edible Coatings For Extended Strawberry Shelf Life, Saklain Niam, Iftekhar Ahmad, Md Abu Rayhan, Sajid Mahmood, Parvej Hasan Jon, Md Monir Ahmed

Food Science Faculty Publications and Presentations

Strawberries deteriorate rapidly under warm, humid conditions, and to make things worse, in many tropical settings refrigerated logistics are limited. Edible biopolymer coatings offer a low-cost method to slow quality loss, but multicomponent formulations behave nonlinearly. In this study, ten types of coatings were developed and evaluated for their effects on the physicochemical (weight loss, firmness, total soluble solids (TSS), pH, color change (Delta E)) and biochemical properties (total phenolic content (TPC), antioxidant property (DPPH) of strawberries over a 6-day storage period at 25 degrees C (298.15K). The optimal formulation, consisting of 0.56 % (w/v) alginate, 0.33 % (w/v) guar …

Effects Of Heat Stress And Depressed Feed Intake On The Cecal And Ileal Microbiota Of Broiler Chickens, Philip M. Campos, Elizabeth S. Greene, Monika Proszkowiec-Weglarz, Sami Dridi

Poultry Science Faculty Publications and Presentations

Chronic heat stress (HS) is known to depress feed intake (FI) and growth in broiler chickens, and may alter the gut microbiota and health, however, the amplitude and duration of each (HS and depressed FI) effect on gut microbiota is still unclear. This study aimed to determine the effects of chronic and acute HS on the cecal and ileal microbiota profiles. Broilers were subjected to thermoneutral (TN, 23 degrees C) or chronic cyclic HS (CHS, 8 h/d, 35 degrees C) condition from d29-42, and one group to acute HS (AHS, 2 h, 35 degrees C) at d42. To distinguish between …

Dynamic Rewiring Of Microrna Networks In The Brainstem Autonomic Control Circuits During Hypertension Development In The Female Spontaneously Hypertensive Rat, Alison Moss, Ankita Srivastava, Lakshmi Kuttippurathu, James S. Schwaber, Rajanikanth Vadigepalli

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

We describe global microRNA (miRNA) changes in the central autonomic control circuits during the development of neurogenic hypertension. Using the female spontaneously hypertensive rat (SHR) and the normotensive Wistar Kyoto (WKY), we analyzed the dynamic miRNA expression changes in three brainstem regions-the nucleus of the solitary tract, caudal ventrolateral medulla, and rostral ventrolateral medulla-as a time series beginning at 8 wk of age before hypertension onset through to extended chronic hypertension. Our analysis yielded nine miRNAs that were significantly differentially regulated in all three regions between SHR and WKY over time. We collated computationally predicted gene targets of these nine …

Minority Farmer And Rancher Delinquency And Local Cultural Climate: Evidence From Farm Service Agency's County Office Committees, Lawson Connor, Bruce L. Ahrendsen, Charles B. Dodson, Logan Moss

Agricultural Economics and Agribusiness Faculty Publications and Presentations

Farm delinquency is linked to many negative indicators of farm survival, including increased risk of bankruptcy and farm failure. Minority farmers and ranchers (MFR) have been found to exhibit higher rates of delinquency on U.S. Department of Agriculture (USDA) Farm Service Agency (FSA) loans compared to their non-Hispanic White male counterparts. These findings persist even after accounting for economic/financial factors expected to predict loan repayment performance. In this study, to further explore the existing discrepancy between loan default rates for MFR and White, non-Hispanic borrowers, we look more broadly than financial indicators and introduce MFR representation on the FSA County …

Measuring The Impact Of Hurricane Incidence On Agricultural Production Risk Using Insurance Data, Hunter D. Biram, Micah Cameron-Harp, Jesse Tack

Agricultural Economics and Agribusiness Faculty Publications and Presentations

Hurricanes are considered among the most destructive natural disasters in the United States. The exposure of agricultural production systems to hurricanes varies between regions in contrast to global risks like commodity price volatility and international trade policies. The regional differences in hurricane exposure may lead to heterogeneity in crop insurance premium rates. This work aims to measure the impact of hurricane incidence on production losses for crops grown in the Mississippi Delta. We leverage a county-month panel of insurance losses spanning 2002-2021 from the US Department of Agriculture Risk Management Agency, and daily data from the National Oceanic and Atmospheric …