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Understanding The Biopsychological Effects Of Trauma On Learning: An Investigation Of Interventions To Support Faculty, Joan Buzick

Seton Hall University Dissertations and Theses (ETDs)

The current era in higher education has brought changes to the academic profession. Faculty have an increasing number of responsibilities in addition to their traditional role as an instructor. At the same time, faculty are engaging with a changing and diverse student population. The population has more challenges, with increased stressors, than have been historically observed in higher education students. For many, the stressors are trauma-related and are a growing concern. Trauma has been shown to impact cognitive, social, emotional, and physical well-being. What has been learned about trauma is, to a great extent, a result of the relatively recently …

Forgetting Fallujah: Covert Silence, Digital Public Memory And The Civilian Consequences Of Operation Phantom Fury In Iraq, Jason L. Jarvis

Journal of Vincentian Social Action

“Forgetting Fallujah” challenges the institutional memory of Fallujah advanced in “US Marines.” For most people, the understanding of war is based entirely on media images (Schwalbe, 2006; Sontag, 2003). This essay, like the work of Jackie Orr (2016) is a salvo in an ideological struggle to re-signify the meaning of Fallujah. The invasion of Fallujah was more severe for civilians than the torture of prisoners at Abu Ghraib, yet Fallujah caused almost no public outcry because it lacked visual evidence and went uncovered by mainstream American media (Entman, 2006). Covert silence in “US Marines” demonstrates that digital memory is easily …

Assessing The Competitive Advantage Of Carbonic Anhydrase In Estuarine Microalgae Through Removed Enzymatic Activity, Eilea R. Knotts

Theses and Dissertations

Carbon concentrating mechanisms (CCMs) are used by photoautotrophs to overcome possible limitations in carbon acquisition but the competitive strategies and efficiencies of these mechanisms among photosynthesizers can be variable. The diversity in carbon acquisition abilities establishes the potential for alterations in community structure with shifting carbon concentrations. Given the role of phytoplankton and benthic microalgae (BMA) in the trophodynamics of estuaries, understanding the mechanisms of carbon acquisition in these systems is important in predicting how primary productivity and nutrient cycling might change in response to increasing concentrations of atmospheric CO2. Our approach to investigate whether induced carbon limitation would show …

Controls And Adaptive Management Of Nitrification In Agricultural Soils, Jeanette M. Norton, Yang Ouyang

Plants, Soils, and Climate Faculty Publications

Agriculture is responsible for over half of the input of reactive nitrogen (N) to terrestrial systems; however improving N availability remains the primary management technique to increase crop yields in most regions. In the majority of agricultural soils, ammonium is rapidly converted to nitrate by nitrification, which increases the mobility of N through the soil matrix, strongly influencing N retention in the system. Decreasing nitrification through management is desirable to decrease N losses and increase N fertilizer use efficiency. We review the controlling factors on the rate and extent of nitrification in agricultural soils from temperate regions including substrate supply, …

Effects Of Alternative Carbohydrate Sources And Soybean-Derived Isoflavones On The Microbiome And Immune System Of Nursery Piglets And Intestinal Porcine Epithelial Cell Line J-2, Sydney Kinstler

Department of Animal Science: Dissertations, Theses, and Student Research

Four experiments were conducted to characterize the microbiome of the piglet and observe effects of diet on growth performance and immunity. In Exp. 1, 96 nursery piglets were fed varying carbohydrate sources and in Exp. 2, 64 piglets were fed a soy protein concentrate or soybean meal as-is or supplemented with an isoflavone concentrate. Body and feeder weights were measured for growth performance estimation. Luminal contents and scrapings were isolated for microbial composition analysis. Fecal and blood samples were extracted in Exp. 2 for microbiome and immunity analysis. Diets did not affect growth performance (P > 0.10); however, Exp. 1 …

Explorations And Collaborations On Two Under-Recognized Native American Food Crops: Southwest Peach (Prunus Persica) And Navajo Spinach (Cleome Serrulata), Reagan C. Wytsalucy

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Agricultural production among the Native American populations of the Southwest declined significantly during the twentieth century. Corn, beans and squash, the three most recognized traditional food crops, remains widespread, but knowledge regarding the traditional management of these crops was lost. The loss of traditional knowledge for Southwest Indigenous Nations was more pronounced for the Southwest peach (Prunus persica) and Navajo spinach (Cleome serrulata Pursh). The Navajo, Hopi, and Zuni Nations are all seeking to increase the availability of traditional crops for their original uses, such as for food and wool dye. In order to revitalize traditional agriculture …

Targeting Pathogenic Lafora Bodies In Lafora Disease Using An Antibody-Enzyme Fusion, M. Kathryn Brewer, Annette M. Uittenbogaard, Grant L. Austin, Dyann M. Segvich, Anna Depaoli-Roach, Peter J. Roach, John J. Mccarthy, Zoe R. Simmons, Jason A. Brandon, Zhengqiu Zhou, Jill Zeller, Lyndsay E. A. Young, Ramon C. Sun, James R. Pauly, Nadine M. Aziz, Bradley L. Hodges, Tracy R. Mcknight, Dustin D. Armstrong, Matthew S. Gentry

Molecular and Cellular Biochemistry Faculty Publications

Lafora disease (LD) is a fatal childhood epilepsy caused by recessive mutations in either the EPM2A or EPM2B gene. A hallmark of LD is the intracellular accumulation of insoluble polysaccharide deposits known as Lafora bodies (LBs) in the brain and other tissues. In LD mouse models, genetic reduction of glycogen synthesis eliminates LB formation and rescues the neurological phenotype. Therefore, LBs have become a therapeutic target for ameliorating LD. Herein, we demonstrate that human pancreatic α-amylase degrades LBs. We fused this amylase to a cell-penetrating antibody fragment, and this antibody-enzyme fusion (VAL-0417) degrades LBs in vitro and dramatically reduces LB …

Animal Science Department News, Department Of Animal Science

Animal Science Newsletters

No abstract provided.

The Role Of The Gut Microbiome In Tumor Development And Response To 5-Fluorouracil In The Apc^Min/+ Mouse, Kristen Michele Hogan

Theses and Dissertations

Colorectal cancer (CRC) is the third most frequent cancer and the second leading cause of cancer related deaths. While CRC is initiated by mutations in critical tumor suppressor genes, its development and progression to malignancy is aided by host derived cells that are recruited to the tumor microenvironment (TME) and by cancer-associated microbiota that constitute the gut microbiome. Components of the gut microbiota have been shown to alter immune cell infiltration into tumors and influence response to therapy, disease stage, and patient survival. In previous studies, we found that ApcMin/+ mice, a model of early colon carcinogenesis, had reduced tumor …

Failure Of Oxysterols Such As Lanosterol To Restore Lens Clarity From Cataracts, Damian M. Daszynski, Puttur Santhoshkumar, Ashutosh S. Phadte, K. Krishna Sharma, Haizhen A. Zhong, Marjorie F. Lou, Peter F. Kador

School of Veterinary and Biomedical Sciences: Faculty Publications

The paradigm that cataracts are irreversible and that vision from cataracts can only be restored through surgery has recently been challenged by reports that oxysterols such as lanosterol and 25-hydroxycholesterol can restore vision by binding to αB-crystallin chaperone protein to dissolve or disaggregate lenticular opacities. To confirm this premise, in vitro rat lens studies along with human lens protein solubilization studies were conducted. Cataracts were induced in viable rat lenses cultured for 48 hours in TC-199 bicarbonate media through physical trauma, 10 mM ouabain as Na+/K+ ATPase ion transport inhibitor, or 1 mM of an experimental compound that induces water …

Messy Eating, Samantha King, R Scott Carey, Isabel Macquarie, Victoria Millious, Elaine Power

Environment

Literature on the ethics and politics of food and that on animal-human relationships have infrequently converged. Representing an initial step towards bridging this divide, Messy Eating features interviews with thirteen prominent and emerging scholars about the connections between their academic work and their approach to consuming animals as food. The collection explores how authors working across a range of perspectives—postcolonial, Indigenous, Black, queer, trans, feminist, disability, poststructuralist, posthumanist, and multispecies—weave their theoretical and political orientations with daily, intimate, and visceral practices of food consumption, preparation, and ingestion.

Contributors: Neel Ahuja, Billy Ray Belcourt, Matthew Calarco, Lauren Corman, Naisargi Dave, Maneesha …

Coral Microbiome Database: Integration Of Sequences Reveals High Diversity And Relatedness Of Coral-Associated Microbes, Megan J. Huggett, Amy Apprill

Research outputs 2014 to 2021

Coral-associated microorganisms are thought to play a fundamental role in the health and ecology of corals, but understanding of specific coral-microbial interactions are lacking. In order to create a framework to examine coral-microbial specificity, we integrated and phylogenetically compared 21,100 SSU rRNA gene Sanger-produced sequences from bacteria and archaea associated with corals from previous studies, and accompanying host, location and publication metadata, to produce the Coral Microbiome Database. From this database, we identified 39 described and candidate phyla of Bacteria and two Archaea phyla associated with corals, demonstrating that corals are one of the most phylogenetically diverse animal microbiomes. Secondly, …

Orthorexia Nervosa Among Collegiate Female Student-Athletes, Maryse Bard-Martel

Graduate Theses/Dissertations

Orthorexia nervosa (ON) is a specific style of disordered eating defined as an unhealthy obsession with eating healthy food, or going to extremes in the pursuit of a diet that is supposed to be good for you. The purpose of this study was to explore the prevalence of orthorexia nervosa tendencies in college female soccer players in the NCAA Division 1. Purposive sampling was used, and participants were current student-athletes from the Missouri State women’s soccer team (n=18). Survey research was utilized to assess athletes’ attitudes and behaviors related to various aspects of diet and training, and the control it …

How Successful High School Boys Soccer Coaches Perceive And Develop Cultural Competency: A Grounded Theory Approach, Lauren Jefferson

Masters Theses, 2010-2019

The purpose of this study was to examine how high school athletics coaches conceptualize the knowledge, values, and skills of cultural competence, with specific attention to learning processes and influences. In order to serve the increasingly diverse U.S. student population equitably and to the full holistic potential of extracurricular programming, high school coaches must develop a greater comfort with and capacity for exercising cultural competency. A qualitative approach using a grounded theory was applied. Seven coaches and one athletic director were recruited by purposive sampling. The research suggests a process-oriented, chronological model of how experienced coaches begin to work with …

Attitudes Toward Animal Research And Experimentation: An Annotated Bibliography [2001-2010], Erich Yahner

Anthrozoology

No abstract provided.

Notch Inhibitors And The Bet Inhibitor Jq-1 Decrease The Growth Of Primary Tumor Cells Derived From A Novel Mouse Model Of C11orf95-Rela Induced Brain Tumor, Ericka Randazzo, Jesse Dunnack, Justin Fang, Joseph Loturco Phd

University Scholar Projects

Brain tumors are the most common childhood solid malignancy, and because of remarkable advances in treating many cancers outside of the brain, they have become the leading cause of cancer mortality in children. Ependymomas are a class of brain tumors which can be further subdivided into three groups based upon their location and genetic features. Of the three classes, supratentorial ependymomas are the only subgroup known to be marked by an oncogenic driver gene, which consists of a fusion mutation between the C11orf95 and RELA genes. C11orf95-RELA positive tumors are the most aggressive and lethal of …

The Dna Damage Response Gene Ddr48 Regulates Sterol Synthesis Genes To Confer Antifungal Resistance To The Pathogenic Fungus Histoplasma Capsulatum, Gabriella Reyes

Honors Theses

Histoplasma capsulatum is a dimorphic fungal pathogen that is endemic to the Ohio, Missouri, and Mississippi river valley regions. The fungus grows as a mold at environmental temperatures (25C) and transforms into a unicellular yeast upon inhalation by a mammalian host (37C). The mold to yeast shift is required for pathogenicity in host organisms, where the potentially fatal disease, histoplasmosis, can present. This study aims to characterize the DNA damage response protein DDR48 and the role that it plays in combating cellular stressors in H. capsulatum. We found that DDR48 is expressed strongly in the mold phase but expressed only …

Lingnan Gardeners Bimonthly Newsletter (No. 43) = 嶺南彩園通訊 (第43期), Lingnan Gardeners, Kwan Fong Cultural Research And Development Programme, Lingnan University

Lingnan Gardeners Newsletter 嶺南彩園通訊

Guava 芭樂

Quantifying Expression Of Interneuron Subtype Markers For Dlx-2 Transfected Ng2 Cells, Timothy Nolan

Honors Scholar Theses

Neurons are a post-mitotic cell population, and therefore, they are not able to regenerate in vivo after a traumatic injury. Because inhibitory GABAergic interneurons and oligodendrocyte precursor cells (OPCs) are derived from the same precursor, recent studies have focused on transforming these OPCs into GABAergic neurons. However, there are different types of GABAergic interneurons that have different electrophysiological responses, which can lead to functional differences. The Nishiyama laboratory had already used a key gene in GABAergic interneuron and OPC differentiation, Distal-less homeobox 2 (Dlx-2), to transfect OPCs; early electrophysiology tests showed most of these transfected cells behaved like immature neurons, …

Delineation Of Events In Centripetal Migration During Drosophila Oogenesis, Travis Tait Parsons

UNLV Theses, Dissertations, Professional Papers, and Capstones

All multicellular organisms initially start out as a single cell. This cell must use the genetic information encoded in its DNA to multiply in number and build itself into a complex multicellular organism. How this process occurs is the focus of developmental biology, a field that seeks to understand how a combination of genetic information and environmental conditions shape a cell from its beginnings as a zygote all the way to maturity. A fundamental part of this process is the ability of cells to work together in order to build complex tissues and organs. Cells achieve this coordination by using …

Macrophage Infiltration And Activation In Old And Young Skeletal Muscle Following Lengthening Contractions, Jamie P. Kaluhiokalani, Jacob R. Sorensen, Robert D. Hyldahl

Library/Life Sciences Undergraduate Poster Competition 2019

•Human skeletal muscle is capable of robust regeneration following damage. •Muscle repair following injury is dependent on the timely activity of pro-inflammatory (M1) and anti-inflammatory, pro-regenerative (M2) macrophages. Following acute muscle injury, healthy skeletal muscle experiences a rapid and vigorous inflammatory response. •Macrophages clear necrotic tissue and facilitate satellite cell behavior through the secretion of cytokines and growth factors. •It is known that aged muscle experiences poor regenerative potential following injury, but the cause is not well-understood.

Purpose: The purpose of this study was to investigate macrophage behavior in old and young people in the context of muscle damage.

Hypothesis: …

Sexual Assault On College Campuses: The Links Between Hegemonic Masculinity, College Sports, And Sexual Violence, Vanessa Iroegbulem

Sexual Ethics

This paper seeks to explore the social and neurobiological factors that shape men into sexual aggressors by rewarding violent behaviors. It will critique the exploitation and the commodification of male bodies through sports, namely football.

Effect Of Trb3 On Skeletal Muscle Mass Regulation And Exercise-Induced Adaptation, Ran Hee Choi

Theses and Dissertations

Skeletal muscle, which composes over 40% of body mass, is responsible for daily locomotion and energy metabolism. It is a malleable tissue that can adapt its structure and function in response to internal and external environmental stimuli. Changing muscle mass and energy substrate utilization is a common skeletal muscle adaptation in response to various pathological conditions, including type 2 diabetes and obesity. Failure to maintain skeletal muscle mass and function has been correlated with increasing morbidity and mortality, as well as poor quality of life. Hence, maintenance of skeletal muscle integrity is a recommended strategy in achieving better quality of …

漫長的八十年代 : 蔬菜、菜農與香港構成, Sze Chung Chow

Lingnan Theses (MPhil & PhD)

流行說法與學術文獻裡，香港戰後農業發展得益於始自1946年的蔬菜統營系統，八十年代逐漸被國内進口菜打擊。無論同情與否，菜農都被描繪為受害／被動者，本研究嘗試超越這視角，提出殖民管治大計既無法馴化菜農，後者亦不能被簡化為内地進口菜的受害者。

借助文化研究的歷史知識論（historical epistemology，見Hall, 2003）、歷史資本主義（historical capitalism，見 Polanyi 1957 ; Braudel 1982）、社會史／庶民研究（social history/ subaltern studies，見 Guha 1997 ; Scott 2009）、行動者網絡理論（actor-network theory，見Latour 2005）等理論視野，本研究試圖開展以本地農業軌跡為本的批判進路，反思農業不斷重組的過程。

研究結果顯示：蔬菜業於殖民地年代並非馴服、被妥貼規管對象，業界積極在内地開設菜場，甚至一度可視為「中港融合」的「典範」，同時曝露出其限制。蔬菜業與市場競爭／發展並不矛盾，特大地理範圍裡的激進商品化，卻改寫了蔬菜、香港的性質與意義。

研究貢獻有三：首先為菜農及蔬菜提供了一種超越國族框架、發展主義的動態理解，補充香港研究、單一學科的狹隘視野；第二，文化研究、歷史資本主義、社會史／庶民研究、行動者網絡的交錯引用，與香港農業史對照和對話，亦豐富了這些潛藏互補可能性的理論傳統；第三，從庶民及蔬菜的角度，補充現存香港故事的某些空白。一方面鬆縛了關於農民及廣義香港人在論述上的被動性，另一方面攞脫人類中心的觀點，考察蔬菜的生產、消費、呈現、身份、規管等環節，如何局部地形構香港社會，及在更廣闊的尺度裡定位「香港」與其他地區的關係，提供一種將狹獈、簡化「本土」觀問題化的視角。

論文主要部份有五章，第一章介紹本研究所採用的方法，並闡釋有關的理論視野與本研究的相關之處及限制。第二章嘗試將新界「問題化」，指出「新界」與「内地」的區分，並非如官式文件般清晰和理所當然。第三章指出在政府統計數據裡「隱形」的農業部門，並不服務殖民地的國民經濟體系，有其自身邏輯與規律。第四章透過八十年代「毒菜心j的兩宗事件，重組所謂「香港農業式微」的社會及制度脈絡，並問題化「香港」和「内地」的對立。第五章分析近年成為本港「菜籃子」寧夏的供港菜場。筆者認為，與其說是「北進」，供港菜場自八十年代其實不斷向「北退」，是一個前境未見樂觀的「中港融合」故事。

Genomics Based Approaches To Fungal Evolution, Aaron J. Robinson, Donald O. Natvig

Biology ETDs

Advances in DNA sequencing and data analysis make it possible to address questions in population genetics and evolution at the genomic level. Fungi are excellent subjects for such studies, because they are found in diverse environments, have short generation times, can be maintained in culture and have relatively small genomes. My research employed genetic approaches using a variety of sequencing technologies and methods of analysis to explore questions in fungal evolution.

In one study, I explored the genetics behind differences in thermotolerance between isolates of Neurospora discreta from Alaska and New Mexico. Isolates from the two states exhibited differences in …

Indonesia And Central Asia: Romanticizing Authoritarian Regime In The Past?, Mochamad Aviandy

International Review of Humanities Studies

Even though countries in Central Asia and Indonesia seem to be unrelated, both actually have experienced authoritarian regime and implemented decentralization system after that regime collapsed. Nevertheless, decentralization along with non-authoritarian regime does not automatically bring the desired good result since a new authoritarian regime based on decentralization appears. As a result, the citizens long for the welfare of the centralism system. Before talking further about the comparison of both regions, it is better to have a good understanding of each region.

Childhood And A Culture Of Fear In Lemony Snicket’S A Series Of Unfortunate Events, Nur Aini Annapurna, Dhita Hapsarani

International Review of Humanities Studies

This article is an excerpt from an undergraduate thesis of the same title which focuses on A Series of Unfortunate Events, a children‟s book series by Lemony Snicket. This thesis explores how a culture of fear shapes childhood, which is represented in the series. By using qualitative textual analysis the research discusses how the series represent the way childhood is shaped by a culture of fear through the depiction of various characters and social institutions in the novels. This research also explores the author‟s attempts in challenging the notion that children are vulnerable by analyzing the Baudelaires‟ identity and vulnerability. …

A Rational Approach For Creating Peptides Mimicking Antibody Binding, Sameer Sachdeva, Hyun Joo, Jerry Tsai, Bhaskara Jasti, Xiaoling Li

School of Pharmacy Faculty Articles

This study reports a novel method to design peptides that mimic antibody binding. Using the Knob-Socket model for protein-protein interaction, the interaction surface between Cetuximab and EGFR was mapped. EGFR binding peptides were designed based on geometry and the probability of the mapped knob-sockets pairs. Designed peptides were synthesized and then characterized for binding specificity, affinity, cytotoxicity of drug-peptide conjugate and inhibition of phosphorylation. In cell culture studies, designed peptides specifically bind and internalize to EGFR overexpressing cells with three to four-fold higher uptake compared to control cells that do not overexpress EGFR. The designed peptide, Pep11, bound to EGFR …

Media Ethnography: Demands Alternative, Bishal Kumar Bhandari Mr

The Qualitative Report

The heart and soul of ethnography lies in anthropological study within specific caste, ethnicity, and gender. In mass media research, the anthropological ethnography dominates through some of the aspects that focuses on geographical locations and ethnicity which is not relevant in the age of media and technology. The mass media has gained its own gravity, uniqueness, and distinctiveness at present as it fulfills the need and interest of individuals/society. As such fieldwork, participants, and positioning a debate within the realm of “anthropological ethnography” is not sufficient to understand the subjectivities of mass media. In such a context, this article analyzes …

Student Led Area Measurement Assessments Using Virtual Globes And Pictometry Web-Based Interface Within An Undergraduate Spatial Science Curriculum, David Kulhavy, I-Kuai Hung, Daniel Unger, Yanli Zhang

Faculty Publications

The use of Virtual Globes and Pictometry continues to expand and develop in undergraduate spatial science education. Spatial science undergraduates measured the area of 30 rectangles on the earth’s surface and compared them to Pictometry hyperspectral imagery measurements within a web-based interface and the Google Earth interface compared to ArcGIS Explorer, Map Developers and ArcMap using the ArcMap 10.5.2 interface. An analysis of variance of the absolute mean area errors (p-value of 0.009271) concluded the accuracy of the five area measurements were statistically different at the 95% confidence interval. A Tukey pair-wise test found that the Pictometry and Google Earth …