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Exercise As A Non-Pharmacological Intervention For The Prevention And Delay Of Alzheimer’S Disease And Dementia, Eden Culver

Honors Theses

Alzheimer’s disease (AD) and related dementias are rapidly increasing public health concerns due to aging populations and rising life expectancy. Alzheimer’s disease is characterized by progressive neurodegeneration associated with amyloid-β plaques, tau neurofibrillary tangles, neuroinflammation, oxidative stress, and neuronal loss, leading to impairments in memory, cognition, and daily functioning. Because there is currently no cure for Alzheimer’s disease, identifying effective non-pharmacological prevention strategies is essential. This paper examines the role of physical exercise as a preventive and protective intervention for delaying the onset and progression of Alzheimer’s disease and dementia. Current research demonstrates that exercise supports brain health through several …

Scientific Research In Cuba: A General Analysis With A Special Focus On Energy, Agriculture And Technology, Henri Dou, Pierre Fournie

International Journal of Islands Research

An analysis of science in Cuba is carried out using data from the OpenAlex database. Examples are developed: agriculture, rice, technology in relation to the current situation: national food supply, energy and medicine. The predominance of research in biology and medicine and the low commitment in the fields of agriculture, energy, medicinal plants and technology are highlighted. Various development schemes are proposed. The conclusion is that research must be directed towards strategic areas: food and energy, must be less dispersed and that technology must be better taken into account. Three proposals are made: the development of a chemical analysis platform …

Single-Walled Carbon Nanotube-Mediated Plasmid Dna Delivery In The Model Monocot Brachypodium Distachyon, Kaya İşleyen Bi̇lge, Bahar Soğutmaz Özdemi̇r

Turkish Journal of Biology

Background/aim: Plant genetic engineering is a valuable approach for improving stress tolerance, crop productivity, and quality traits. However, its progress is limited by the drawbacks of traditional transformation methods. Commonly used techniques, such as Agrobacterium-mediated transformation and biolistics, are restricted by genotype dependency, lengthy tissue culture steps, and low efficiency, particularly in monocot species. Therefore, the development of alternative gene delivery strategies remains an ongoing research focus in plant biotechnology. Nanoparticle-based delivery systems have recently gained attention due to their physiochemical properties, biocompatibility, and potential for alternative gene delivery approaches in plant systems.Materials and methods: We investigated the use of …

Combinatorial Effect Of Epirubicin And 5-Fluorouracil In The Treatment Of Temozolomide-Resistant Glioblastoma Cells, Mehrsa Bayat, Muhli̇s Akman, Türker Kiliç, Ti̇muçi̇n Avşar

Turkish Journal of Biology

Background: Glioblastoma (GBM) is a highly aggressive form of brain tumor characterized by rapid proliferation and invasiveness. It is associated with a poor prognosis due to acquired resistance to temozolomide (TMZ). In this study, we investigated whether a combination of epirubicin, 5-fluorouracil (5-FU), and TMZ could improve TMZ sensitivity in resistant GBM cells and help overcome resistance.Materials and methods: TMZ resistance was established in the U87MG cell line. The MTT assay was used to measure cell viability. Reactive oxygen species (ROS) and apoptosis were measured using flow cytometry. RNA-seq was used to evaluate genomic changes based on treatment with drugs …

Comparative Evaluation Of Curd Enriched With Essential Oils Derived From Dill, Caraway, And Cumin, Hafize Fidan, Toncho Kolev, Denis Dervish, Ivayla Dincheva, Ira Taneva, Serkan Yilmaz, Yusuf Şavşatli, Albena Stoyanova

Turkish Journal of Agriculture and Forestry

Curd cheese is a traditional dairy product that, in recent years, has increasingly been supplemented with various functional additives aimed at enhancing its aroma and flavor profile, improving overall quality, and extending shelf-life. The objective of the present study was to conduct a comparative evaluation of changes in selected physicochemical, microbiological, and sensory parameters of curd cheese enriched with 0.01% essential oils derived from dill (Anethum graveolens L.), cumin (Cuminum cyminum L.), and caraway (Carum carvi L.) fruits. Fatty acid profiling revealed a reduction in saturated fatty acids and an increase in oleic and linoleic acids in essential oil-enriched curds …

Silicon-Mediated Enhancement Of Wheat Tolerance To Drought Stress: A Comparative Study Of Antioxidant Activity, Photosynthesis, Secondary Metabolites, And Yield, Abida Kausar, Rida Yasmeen, Shahid Iqbal, Muhammad Bilal Hafeez, Asif Mukhtiar, Sadia Azeem, Ali Raza, Samreen Nazeer, Muhammad Zubair Akram, Muhammad Kamran, Fahd Rasul, Noreen Zahra

Turkish Journal of Agriculture and Forestry

Drought stress (DS) is a major constraint on optimal plant growth and yield. Agricultural researchers have been actively exploring fertilizers that can enhance crop production under DS conditions. Silicon (Si) application has emerged as a promising strategy for managing DS in various crops. This study investigated the potential of Si soil drenching to mitigate the adverse effects of varying levels of DS (at 100%, 70%, and 40% field capacity) in wheat. Two varieties (Ujala-2016 and FSD-2008) were used to evaluate the influence of Si (2.5 mM) on antioxidant activity, oxidative burst, secondary metabolites, growth, and yield. The results indicated that …

Biomechanical Effects Of Bilateral Torsion And Skeletal Fusion: A Case Study, Linnéa Forbes

Honors Projects

As part of both a personal endeavor and an academic project, I have investigated the aetiology and treatment of seemingly idiopathic and debilitating leg pain in a patient over the past 10 years. Via collaboration with medical professionals at Cincinnati Children’s Hospital, Cincinnati Premier Physical Therapy, and Cincinnati Women’s TriHealth, I have identified sources of pain at the anatomical level. The combination of internal femoral torsion, external tibial torsion, pes planus, and bony fusions appear to be major perpetuators of the pain. An effective treatment continues to be evasive. To date, I have attempted to find answers through genetic approaches, …

Quantifying Sleep Wake Rhythms In The Hospital Environment With Digital Technologies, Carsten Skarke, Nadim El Jamal, Michael V. Genuardi, Thomas G. Brooks, Antonijo Mrčela, Nicholas F. Lahens, Makayla Cordoza, Sean Sarles, Amarachi Mbadugha, Dineth R. Karunamuni, Shikhar Gupta, Charles J. Bae, Amita Sehgal, Thomas P. Cappola, Jacob T. Gutsche, Pavan Atluri, Nimesh D. Desai, Michael A. Acker, Gregory R. Grant, Richard J. Schwab, Ilene M. Rosen, Garret A. Fitzgerald

Division of Cardiology Faculty Papers

Postoperative clinical care is prone to circadian desynchronization that may influence health outcomes. In an exploratory, feasibility-oriented and signal-exploration effort, we collected 1.8 million data points using 11 remote sensors during preoperative, in-hospital and post-discharge settings in 13 elective cardiac surgery patients (5.2% enrolled from 252 screened). We found that room traffic continued during nighttime with ≥1 visit/h. Sound levels exceeded the recommended 45 dBA threshold (51.9 ± 3.3 vs. 48.3 ± 4.2 dBA during nighttime). Brightness dropped at night (89.9 ± 87.7 to 3.7 ± 9.8 lux), but bright light exposures occurred. Ambient room temperature lacked sleep-inducing diurnal variability. …

Modulating Microtubule Stability Via Α-Tubulin Acetylation Partially Restores Golgi Fragmentation In Spinal Muscular Atrophy, Peli̇n Zobaroğlu Özer, Memet Gözüböyük, Özge Çeti̇n, Niko Hensel, Güzi̇n Emecen, Adam Malik, Melissa Bowerman, Peter Claus, Hayat Erdem Yurter, Gamze Bora Akoğlu

Turkish Journal of Biology

Background/aim: Spinal muscular atrophy (SMA) is a neurodegenerative disease caused by the loss of survival of motor neuron (SMN) protein. SMN deficiency leads to perturbations of the cytoskeleton, including microtubules, which are mainly involved in motilityrelated cellular processes. However, the molecular mechanisms of microtubule dysregulation in SMA remain elusive. Alpha (α)-tubulin is a structural component of microtubules, and its posttranslational modifications affect microtubule dynamics. Here, we aimed to investigate α-tubulin acetylation and related molecular mechanisms in SMA. Materials and methods: Two different SMA mouse models, the Drosophila melanogaster model and patient-derived fibroblasts, were used in the study. Western blot and …

Ankrd2 May Alleviate Denervation-Induced Skeletal Muscle Atrophy By Inhibiting Inflammation, Yalin Zhang, Lin Zhang, Li Li, Liqin Zhang, Li Zeng, Jiaying Qiu, Zhengrong Xi, Wenwen Wang

Turkish Journal of Biology

Background/aim: Sciatic nerve injury causes a loss of skeletal muscle innervation, reduced motor function, and eventual muscle atrophy. Inflammation and increased protein degradation are key factors contributing to muscle atrophy. Inflammation is activated early during muscle atrophy and can be modulated by various factors. However, the precise role of inflammation in denervation-induced muscle atrophy remains unclear. Materials and methods: Transcriptome sequencing was used to determine that the inflammatory response occurs early during denervation-induced muscle atrophy. RT-qPCR validation of several inflammatory factors showed rapid upregulation at early stages, followed by gradual downregulation. Weighted gene coexpression network analysis of differentially expressed genes …

Unusual Rna Polymerase Ii Patterns In Meiotic Prophase I In Nannospalax Xanthodon: Insights Into Chromatin, Telomeres, And Sex Chromosomes, Sergey N. Matveevsky, Ferhat Matur, Faruk Çolak, Andrei Kandaurov, Mustafa Sözen, Svetlana V. Pavlova, Oxana Kolomiets

Turkish Journal of Biology

Background: Meiotic transcription is a highly regulated process involving stage-specific chromatin remodeling and dynamic RNA polymerase II (RNAPII) activity. Nevertheless, our current understanding is largely based on classical model organisms, while many nonmodel mammals remain unexplored. This study investigates the transcriptional dynamics and chromatin features during meiotic prophase I in Nannospalax xanthodon, a subterranean blind mole rat species with extensive intraspecific karyotype variation.Materials and methods: Using immunofluorescence, we analyzed synapsis and transcriptional activity in spermatocyte nuclei of two geographically distant N. xanthodon males, detecting SYCP3, CREST, γH2AFX, and phosphorylated RNAPII (Ser5, Ser2). Telomereassociated proteins RAP1 and TERT were also examined …

Development Of A Grease Resistant Barrier For Food Industry Applications, Mira Marino

Honors Theses

The objective of this project is to develop a grease-resistant barrier coating for paper-based food packaging and to evaluate the economic feasibility of implementing this coating system at an industrial scale. As demand increases, this project focuses on identifying an optimal pigment and binder combination that enhances barrier performance while maintaining cost-effectiveness. The primary goal was to maximize grease and moisture resistance of coated paper while ensuring the process is economically viable and compatible with existing paper mill operations.

The final plant design consists of one continuous stirred tank reactor (CSTR) and three centrifugal pumps integrated into an existing paper …

Investigating The Intra-Host Relationships Of The Microbiota At Multiple Sites, Ariel Jose Hernandez-Leyva

Arts & Sciences Graduate Student Theses and Dissertations

The human body hosts an abundance of microbial communities that, through complex and multi-faceted interactions, interface with host physiology and help govern health and disease. Many of these interactions are beneficial and help maintain host homeostasis or contribute to the metabolic capacity of the host. Some are detrimental, potentially inducing or further exacerbating disease. All are complicated by the vast diversity of microbes that comprise the microbiota at any given site. Identifying microbes or microbial functions that influence health and disease for study and potential use as biomarkers is tantalizing, though difficult. The vast diversity of potential community compositions, redundancy …

Who Will Grow Our Food In The Future? Factors Influencing A-State Agricultural Student’S Intentions To Enter Production Agriculture, Kamana Kafle

Create@State

The future of agriculture depends on what motivates today’s student to pursue careers in production agriculture. This study identifies key drivers of career intention among College of Agricultural students at A-State using an extended Theory of Planned Behavior framework. Data were collected through a cross-sectional survey and analyzed using Partial Least Squares Structural Equation Modeling (PLS-SEM). The model explained a substantial 74.2% of the variance in agricultural career intention. Results revealed that Career Planning was the strongest positive predictor, followed by Attitude Towards Agriculture and Perceived Value. Interestingly, factors such as Perceived Behavioral Control, Subjective Norms, and access to Facilities …

Infertility And Mental Health, Laynie Pugmire

Family Perspectives

No abstract provided.

Fatherhood Redefined: How Paternity Leave Shapes Relationships, Olivia Flores

Family Perspectives

Paternity leave remains limited in the United States, with relatively few fathers granted paid time off following the birth of a child. This literature review examines how paternity leave shapes marital relationships by influencing parental mental health and couple communication during the transition to parenthood. Drawing on interdisciplinary research, the paper synthesizes evidence indicating that fathers’ use of paternity leave is associated with higher marital satisfaction and greater relationship stability. These benefits are largely mediated by improvements in both maternal and paternal mental health, as paternity leave reduces role overload, stress, and symptoms of anxiety and depression for both partners. …

The Effect Of Singlehood On Socioemotional Health, Alexa Garner

Family Perspectives

No abstract provided.

Why Yelling Feels Like The Only Option (And What To Try Instead), Vanessa Brouse

Family Perspectives

No abstract provided.

Swosu Research And Scholarly Activity Fair 2026, Swosu Office Of Sponsored Programs

SWOSU Research and Scholarly Activity Fair Programs

On behalf of the University Research and Scholarly Activity Committee (URSAC) and the Office of Sponsored Programs (OSP) at Southwestern Oklahoma State University, we are pleased to welcome you to the Thirty-Fourth SWOSU Research and Scholarly Activity Fair.

The Impact Of State And Federal Policies On Academic Researchers: Findings From A National Survey, Dylan Ruediger, Chelsea Mccracken, Jonathan Barefield

Copyright, Fair Use, Scholarly Communication, etc.

Key findings

● State and federal policies targeting divisive concepts or DEI are shaping research agendas at scale and across disciplines. Twenty percent of all respondents, and 29 percent of researchers working in states with divisive concepts or similar laws, reported having avoided certain research topics because of state laws and policies.

● Eight percent of respondents representing a wide range of disciplines reported having had a federal grant cancelled in 2025.

● Eleven percent of respondents reported that federal and state policies restricting research activities are compelling them to seek employment out of state, to leave the academy, or …

Impacts Of Climate Change On China’S Agricultural Production And Proposed Countermeasures, Yaning Chen, Yanjun Shen, Ming Jiang

Bulletin of Chinese Academy of Sciences (Chinese Version)

Climate change is among the most severe global challenges today. It directly impacts agricultural production, which is highly dependent on climatic conditions, imposing multi-dimensional and systemic risks and challenges on China’s agriculture. Drawing on observational data and analysis of the literature, this study systematically examines the impacts of climate change on agricultural production in China. Over the past half century, China’s annual mean surface temperature has risen significantly at a rate of 0.31℃ per decade, exceeding the contemporaneous global average. This trend has intensified climatic variability and extremes, disrupted the prior balance of agricultural water resources, and led to the …

Impacts Of Climate Change On Agricultural Production And Adaptation Strategies In Northeast China, Ming Jiang, Aizhen Liang, Peng Qi

Bulletin of Chinese Academy of Sciences (Chinese Version)

As the “stabilizer” of national food security, Northeast China is highly sensitive to climate change. Over the past 60 years, the regional temperature has risen significantly at a rate of 0.034℃/a, which is much higher than the global average of 0.0074℃/a. The improvement of thermal resources has driven a significant northward expansion of high-yield and heat-demanding crops, such as maize and rice. Nevertheless, increased warming has enhanced evapotranspiration demand, which, combined with the expansion of planting scales, has led to a 19.8% increase in agricultural irrigation water consumption over the past 20 years, resulting in a prominent contradiction between supply …

Evaluating The Impact Of Residential Landscape Audits Using 5-Second Water Use Data, Mahmud Aveek, Camilo J. Bastidas Pacheco, David E. Rosenberg, Jeffery S. Horsburgh, Kelly Kopp, Belize A. Lane

Civil and Environmental Engineering Student Research

We used 5-s water use data to evaluate the effectiveness of residential landscape water audits in summer 2022. Fifty-nine households in two northern Utah cities were monitored for 2–5 weeks before and 3–10 weeks after an audit. We found that the distribution of weekly irrigation volumes postaudit was statistically less than the distribution preaudit (significant at the 1.9E10-5 level). Collectively, the participants reduced their landscape irrigation water use by approximately 379,000 L per week (100,300 gal per week; 0.3 acre-feet per week). We also analyzed changes in irrigation event volume, duration, frequency, and the number of days between events at …

The Ways Green Chile Impacts The Land Of Enchantment, Edith Hancock

The Agora

Using a Follow-the-Thing format, this paper shows the process of green chile production from start to finish. From seedlings being planted on a farm, the farming process, production, marketing, distribution, and consumption. It also entails all the actors involved in the process and the unfortuante reality of workers exploitation and inequalities.

Hormetic Ethanol Effects On Fitness And Attraction In Irradiated Aedes Aegypti, Kayden Robey, Gabriel Borg, Immo Hansen

The Agora

Sterile insect technique (SIT) is an increasingly important strategy for controlling mosquito populations while reducing reliance on chemical insecticides and genetically modified organisms. A major limitation of SIT is the reduced fitness and competitiveness of irradiated male mosquitoes, which can compromise population suppression efforts. This study investigates whether hormetic ethanol exposure improves post-irradiation fitness in Aedes aegypti males, a primary vector of dengue, chikungunya, and yellow fever. Adult male mosquitoes were fed either a standard sugar solution or a sugar solution supplemented with 5% ethanol prior to irradiation. Males were sterilized using X-ray irradiation at 50 Gy and assessed for …

The Effects Of Hurricane Helene On Mental Health And Physical Activity, Hunter Smathers, Robyn York, Jarrett Walbolt

Journal of Appalachian Health

Introduction: Hurricane Helene brought widespread damage to Southern Appalachia, disrupting utilities, health care, and recreation. While natural disasters are linked to declines in mental and physical health, few studies have examined their effects on distinct types of physical activity (PA).

Purpose: This study evaluated the effects of Hurricane Helene on perceived stress, depressive symptoms, post-traumatic stress disorder (PTSD) symptomology, and intentional (exercise for health benefits) and incidental (physical labor or transportation) PA. Evacuation status influence was also explored.

Methods: Twenty participants completed assessments four weeks before (BASE), immediately after (0POST), and four weeks after landfall (4POST). Measures included the Perceived …

Nutrition Strategies To Help Children With Arfid Overcome Nutrition-Related Deficiencies, Saul Campos

The Agora

Avoidant/Restrictive Food Intake Disorder (ARFID) is a serious and relatively newly recognized eating disorder that affects children and adolescents. The disorder was formally introduced in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) and is characterized by restrictive eating patterns that lead to significant nutritional deficiencies, weight loss or poor growth, dependence on nutritional supplements, or interference with psychosocial functioning (American Psychiatric Association, 2013). Current estimates suggest that ARFID may affect approximately 1–5% of children and adolescents, though prevalence varies depending on the population studied and diagnostic criteria used (Białek-Dratwa et al., 2022). Unlike other eating disorders, …