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Articles 1171 - 1200 of 50396
Full-Text Articles in Entire DC Network
Buzzes Over Burrows: Bats And Black-Tailed Prairie Dogs In Western Kansas, Patrick L. Geyer
Buzzes Over Burrows: Bats And Black-Tailed Prairie Dogs In Western Kansas, Patrick L. Geyer
Master's Theses or Doctor of Nursing Practice
The native grasslands of the Great Plains and the organisms that inhabit them are threatened by the anthropogenic disturbance of land-use change; prairie dogs (Genus Cynomys) are one such example. These mammals are considered ecosystem engineers due to their behaviors that physically modify the areas they inhabit, directly affecting the resources available to surrounding organisms. Much research exists on established or potential relationships between black-tailed prairie dogs (Cynomys ludovicianus) and other taxa; until recently, one taxon group absent from mentions of an association with black-tailed prairie dogs was bats (Order Chiroptera). Results of acoustic studies in eastern …
The Role Of Tumor Microenvironment In Glioblastoma Multiforme(Gbm) Therapeutic Resistance, Kwesi E. Taylor
The Role Of Tumor Microenvironment In Glioblastoma Multiforme(Gbm) Therapeutic Resistance, Kwesi E. Taylor
Master's Theses or Doctor of Nursing Practice
Despite significant advances in cancer research and treatment, Glioblastoma multiforme (GBM) remains one of the most difficult cancers to treat effectively, with minimal improvement in long-term survival rates over the past few decades. This is largely attributed to tumor heterogeneity and the ability of tumor cells to develop adaptive resistance mechanisms supported by the tumor microenvironment (TME). Although the TME is recognized as a key contributor to tumor progression and therapeutic resistance, the underlying molecular pathways and regulatory genes remain incompletely understood. This study investigated the role of the tumor microenvironment in GBM therapeutic resistance using a bioinformatics approach. Single-cell …
The Critical Role Of Near-Surface Dynamics In Identifying Spawning Areas Of Atlantic Bluefin Tuna In The Gulf Of Mexico, Donald R. Johnson, William J. Teague, Harriet Perry, James S. Franks
The Critical Role Of Near-Surface Dynamics In Identifying Spawning Areas Of Atlantic Bluefin Tuna In The Gulf Of Mexico, Donald R. Johnson, William J. Teague, Harriet Perry, James S. Franks
Gulf and Caribbean Research
Atlantic Bluefin Tuna, Thunnus thynnus (ABFT), migrate long distances to broadcast spawn in the Gulf of Mexico (GOM) basin, the Mediterranean Sea and the Slope Sea (NW Atlantic). These areas have commonalities including a highly dynamic upper ocean eddy environment that draws nutrients from shallow thermoclines and adjacent continental shelves and can provide temporal sanctuaries from some larval predators. In the GOM basin, the Loop Current (LC) and its energetic spin—off eddies sweep weak swimming predators such as jellyfish (Pelagia noctiluca) into lines and aggregations, leaving relatively open areas as temporal sanctuaries for ABFT larvae during the vulnerable …
Oyster Drill (Stramonita Haemastoma Complex) Habitat Preferences In A Shallow Coastal Estuary, Coen Mcgarrah, Cynthia Lupton, Eric Sparks, Jennifer L. Debose
Oyster Drill (Stramonita Haemastoma Complex) Habitat Preferences In A Shallow Coastal Estuary, Coen Mcgarrah, Cynthia Lupton, Eric Sparks, Jennifer L. Debose
Gulf and Caribbean Research
Southern oyster drill snails (Stramonita haemastoma complex) are nuisance organisms within the Gulf of Mexico. This is due to their damaging impact on recovering and farmed oyster (Crassostrea virginica) populations, which are one of the drills’ main food sources. Oyster reef recovery and increased aquaculture production are priorities for Mississippi and the wider northern Gulf coast. The Grand Bay National Estuarine Research Reserve (NERR) hosts multiple oyster reef restoration sites within its boundaries, yet no comprehensive survey of oyster drill abundance has been conducted in this area to date. Additionally, knowledge of oyster drill preferences for sediment …
First Photo-Identification Resighting Of A Male Sperm Whale (Physeter Macrocephalus) Between Guadeloupe, Lesser Antilles And Andøya, Northern Norway, Rocío Prieto González, Lisa Steiner, Zoë Morange, Tiu Similä, Marten Brill, Cédric Millon, Laurent Bouveret
First Photo-Identification Resighting Of A Male Sperm Whale (Physeter Macrocephalus) Between Guadeloupe, Lesser Antilles And Andøya, Northern Norway, Rocío Prieto González, Lisa Steiner, Zoë Morange, Tiu Similä, Marten Brill, Cédric Millon, Laurent Bouveret
Gulf and Caribbean Research
No abstract provided.
Pollutant Load Reduction In Sarasota Bay, Florida (Usa): Target Development, Implementation, And Outcomes, David Tomasko, Mike Wessel, Jon Perry, Chris Anastasiou, Ryan Gandy
Pollutant Load Reduction In Sarasota Bay, Florida (Usa): Target Development, Implementation, And Outcomes, David Tomasko, Mike Wessel, Jon Perry, Chris Anastasiou, Ryan Gandy
Gulf and Caribbean Research
Between 2006 and 2012, seagrass coverage across Sarasota Bay expanded by 1,108 ha, a 28% increase. During the subsequent years of 2012−2020, 830 ha of seagrass were lost, a 16% decline. In response to these findings, resource management efforts focused on determining the likely reason(s) why those 2 periods had such contrasting trends, to come up with strategies to reverse these losses. Based on results from the seagrass data, the 7—y period of 2006−2012 was designated a “reference period” and water quality data were compared against the subsequent 7—y designated “degraded period” of 2013−2019. Annual average chlorophyll-a (chl-a …
Eeg Signatures Of Motor Development In Early Childhood: A Systematic Review, Sonia Khurana, Ashwini Kulkarni, Thomas C. Bulea, Hunter J. Bennett
Eeg Signatures Of Motor Development In Early Childhood: A Systematic Review, Sonia Khurana, Ashwini Kulkarni, Thomas C. Bulea, Hunter J. Bennett
Rehabilitation Sciences Faculty Publications
Background
Early identification of motor developmental disorders is limited due to lack of objective neural markers that characterize typical neurodevelopmental patterns. This systematic review interprets and synthesizes existing evidence to propose a framework of EEG signatures associated with motor development in children aged 0-5 years, which may help inform future benchmarks for early assessment and intervention.
Methods
Following PRISMA guidelines, we searched published and gray literature across five databases between 2000 and 2025 (registered protocol). Included studies examined EEG during task-based, resting-state, or sleep studies linked to motor milestones, task performance, or standardized motor assessments. Study quality was assessed using …
Land Use Influences Dissolved Organic Matter Composition In The U.S. Coastal Critical Zone Network, Aleksandar I. Goranov, Elizabeth V. Whitney, Brian R. Moyer, Katherine L. Tully, Patrick G. Hatcher, Yu-Ping Chhin
Land Use Influences Dissolved Organic Matter Composition In The U.S. Coastal Critical Zone Network, Aleksandar I. Goranov, Elizabeth V. Whitney, Brian R. Moyer, Katherine L. Tully, Patrick G. Hatcher, Yu-Ping Chhin
Chemistry & Biochemistry Faculty Publications
Coastal watersheds are highly productive biogeochemical systems supporting robust coastal fisheries and contributing significantly to the marine gross primary production flux. These ecosystems are comprised of civil infrastructure, farms, forests, and marshes, and their diversity is reflected in the quantity and quality of dissolved organic matter (DOM). Here, we assess the role of farming in influencing DOM from surface waters of six coastal tidal creeks adjacent to forest and farm sites in the US Critical Zone Network. Molecular fingerprinting using electrospray ionization - Fourier transform - ion cyclotron resonance - mass spectrometry revealed that farm-influenced DOM was enriched in nitrogen-, …
Rewwild: Reimagining Environmental And Wildlife Wellbeing Through Innovative Lawn Design, Morgan J. Sandau, Maiya G. Roelen, Katia E. Chavez, Lydia K. Niedermeyer
Rewwild: Reimagining Environmental And Wildlife Wellbeing Through Innovative Lawn Design, Morgan J. Sandau, Maiya G. Roelen, Katia E. Chavez, Lydia K. Niedermeyer
Undergraduate Theses, Professional Papers, and Capstone Artifacts
Manicured, monoculture lawns often dominate private land in urban areas for aesthetic organization. Colonialist roots are embedded in the history of turfgrass lawns and white-picket fences intended to suppress Indigenous knowledge and ways of caring for the diverse land around us. Private land misuse and homogenous lawns are not limited to the United States; the modern lawn contributes to biodiversity loss on a global scale. Humans are concentrated in cities across the world, and urban areas are known to have negative implications for wildlife and habitat, human health, and sustainable resource use. Management of private land in urban settings is …
Assessing Aerobic And Anaerobic Exercise As Therapies For Sarcopenia, Ella B. Farrer
Assessing Aerobic And Anaerobic Exercise As Therapies For Sarcopenia, Ella B. Farrer
Student Research Poster Presentations 2026
Sarcopenia is an age-related condition represented by progressive changes in muscle physiology that results in the loss of muscle mass and strength. The onset varies amongst individuals and can be influenced by various factors. On the cellular level, mitochondrial dysfunction and disruptions at neuromuscular junctions have been associated with the progression of sarcopenia. The condition ultimately reduces mobility, increases mortality, and hinders quality of life in older populations, necessitating an understanding of effective therapies.
Exercise was linked to symptom reduction of sarcopenia. Evidence indicated aerobic exercise and anaerobic exercise influence distinct molecular pathways involved in muscle physiology. Literature assessed the …
Microplastics Effect On Gut Microbiota, Victoria Rae Pellew
Microplastics Effect On Gut Microbiota, Victoria Rae Pellew
Student Research Poster Presentations 2026
Microplastics Effect on Gut Microbiota
PELLEW, V, Misericordia University, 301 Lake Street, Dallas, PA, United States, 18612
Microplastics (MPs) are small plastic particles less than 5mm in size that are present throughout the environment and are commonly found in both food and water, making human exposure unavoidable. Ingestion occurs through consuming contaminated food, inhalation by breathing airborne particles, and dermal contact via phone cases or skin care products. Once absorbed into the body, MPs may influence human health by altering the gut microbiome.
Results from human fecal studies and in vitro models have shown that MPs can alter pathways associated …
Increasing Temperatures And Heatwave Durations Negatively Affect The Performance Of A Dietary Generalist, Kailey G. Hicks, Claire Guzinski, Mariana Abarca, Mayra C. Vidal, Audrey M. Mitchell, Dhaval K. Vyas, Shannon M. Murphy
Increasing Temperatures And Heatwave Durations Negatively Affect The Performance Of A Dietary Generalist, Kailey G. Hicks, Claire Guzinski, Mariana Abarca, Mayra C. Vidal, Audrey M. Mitchell, Dhaval K. Vyas, Shannon M. Murphy
Biological Sciences: Faculty Publications
Climate variability has increased in recent decades, and this trend is predicted to continue. Globally, there is a rise in extreme temperatures, such as heatwaves, which are strengthening in both intensity and frequency. As ectotherms, insects are especially affected by temperature variation. Insects are the most speciose group of animals and important members of most terrestrial ecosystems, providing critical ecosystem services. Most studies of global change have investigated only a single stressor, yet insects rarely experience one stressor at a time. Two stressors that co-occur are heatwaves and warming temperature regimes; thus, is it important that we study their interaction …
Bringing Awareness And Education To Rural Areas About The Role Occupational Therapy (Ot) Has In Infant Care, Makenzi Richwald
Bringing Awareness And Education To Rural Areas About The Role Occupational Therapy (Ot) Has In Infant Care, Makenzi Richwald
Occupational Therapy Doctorate Capstone Posters
This capstone project focused on education and advocacy. The aim of my capstone project was to provide education to parents of eastern Kentucky (KY) about what Occupational Therapy (OT) can address with infants aged 0-18 months. I saw a gap in knowledge in the eastern KY community about what OT could do for infants and wanted to address this. Through my research, consultation with my mentors, and collaboration with the occupational therapists at my site (BPT) I discerned 14 areas of development and/or common reasons of needed referral for OT services by this age group. These educational materials aimed to …
Physical Activity Among Active-Duty Us Military Servicemembers With Overweight And Obesity, Natalie M. Yarish, Jessica L. Morse, Jennalee S. Wooldridge, Erin E. Dooley, Niloofar Afari
Physical Activity Among Active-Duty Us Military Servicemembers With Overweight And Obesity, Natalie M. Yarish, Jessica L. Morse, Jennalee S. Wooldridge, Erin E. Dooley, Niloofar Afari
Exercise Science Faculty Publications
Background
To examine physical activity (PA) among US military servicemembers (SM) with overweight and obesity (OW/OB) and if they meet Physical Activity Guidelines (PAG). To assess differences in PA by sex and associations between PA and body composition.
Methods
PA duration and intensity were objectively collected via accelerometers and self-reported daily average via self-report International Physical Activity Questionnaire (IPAQ) among US active-duty SM (n=113, 58% female, Mean BMI = 33.3 ± 3.9 kg/m2). Sex, body mass index (BMI), and body fat % (BF% via circumference and an equation) were measured. Accelerometer PA and sedentary time were computed for IPAQ categories …
The Impacts Of Wing-Flashing By Northern Mockingbirds On Foraging, Parental Care, And Reproductive Success, Anna Reece Starman
The Impacts Of Wing-Flashing By Northern Mockingbirds On Foraging, Parental Care, And Reproductive Success, Anna Reece Starman
Undergraduate Research Awards
Foraging efficiency may be enhanced by flashing patches of white wing and tail feathers and has been documented in several avian species. Northern Mockingbirds (Mimus polyglottos, NOMO) exhibit this “wing-flashing” (WF) behavior while foraging, during displays, and in response to predators. In NOMOs, WF has been hypothesized to increase foraging success, but previous findings are inconclusive. To further investigate the biological role(s) of WF behavior in NOMOs, the ventral surface of white primary feathers of male NOMOs were artificially darkened and the foraging and provisioning rates of undarkened (control) males and their mates were compared. While foraging, undarkened males performed …
Granulomatous Cellular Signatures In Nontuberculous And Tuberculous Mycobacterial Infections, Brianna M. Doratt, Ethan G. Napier, Mahdi Eskandarian Boroujeni, Sarah Douglas, Michael H. Davies, Luiz Bermudez, Eliot Spindel, Erin F. Mccaffrey, Ilhem Messaoudi
Granulomatous Cellular Signatures In Nontuberculous And Tuberculous Mycobacterial Infections, Brianna M. Doratt, Ethan G. Napier, Mahdi Eskandarian Boroujeni, Sarah Douglas, Michael H. Davies, Luiz Bermudez, Eliot Spindel, Erin F. Mccaffrey, Ilhem Messaoudi
Microbiology, Immunology, and Molecular Genetics Faculty Publications
Mycobacterium tuberculosis (Mtb) and nontuberculous mycobacteria (NTM) are acid-fast bacilli that trigger granuloma formation, a hallmark immune response aimed at containing infection. While the biology of Mtb granulomas has been widely investigated, far less is known about granulomas caused by NTM infection, despite the increasing prevalence and clinical challenge of NTM cases worldwide. Because granulomas influence infection control, pathology, and treatment response, understanding their cellular organization and signaling is critical to improving therapeutic strategies. Therefore, we characterized granulomas formed following infection of rhesus macaques with Mycobacterium avium subsp. hominissuis (MAH) and compared them to granulomas from cynomolgus macaques infected with …
Long-Term Banding And Encounter Patterns Of Cinnamon Teal Banded In Utah (1960-2025), Gracie A. Henrie
Long-Term Banding And Encounter Patterns Of Cinnamon Teal Banded In Utah (1960-2025), Gracie A. Henrie
Undergraduate Theses, Professional Papers, and Capstone Artifacts
Utah is a valuable breeding and nesting ground for a number of waterfowl species, largely because of the Great Salt Lake, which supports over 400,000 acres of wetland habitat (Ducks Unlimited, n.d.). The Utah Division of Wildlife Resources manages 24 wildlife management areas (WMAs) with the purpose of creating high quality waterfowl habitat in these wetlands that can be enjoyed by hunters, recreators, and birds alike (Wildlife/Waterfowl Management Areas (WMAs), 2025). Effective management is supported with an understanding of the movement and demographic patterns of the waterfowl species the WMAs are designed to support. Bird banding is one tool managers …
Inpatient Stroke Quality Improvement, Briyawna N. Wyatt
Inpatient Stroke Quality Improvement, Briyawna N. Wyatt
Doctor of Nursing Practice (DNP) Scholarly Projects - Archive
Inpatient nursing documentation for stroke care is essential for meeting quality metrics, maintaining continuity, and supporting timely decisions. Gaps can lead to inconsistent care, metric failures, and reduced staff confidence. This quality improvement initiative aimed to improve metric compliance, documentation consistency, and nursing knowledge and satisfaction. A three-part intervention included targeted education, a standardized documentation verification form, and ongoing feedback from stroke champions. Outcomes measured were metric compliance, knowledge (pre/posttests), documentation completeness (Venous Thromboembolism (VTE), education, Modified Rankin Scale), and staff satisfaction. Results showed significant improvement in nursing knowledge (p < .005), reduced metric fallouts, and better documentation across all indicators. Staff satisfaction increased by about 20%. Overall, combining education, standardized tools, and continuous feedback improved documentation practices, enhanced compliance with stroke metrics, and increased nursing knowledge and satisfaction, supporting better care processes and patient outcomes.
Herbivore Cues And Plant Damage-Associated-Compounds Jointly Alter Seed Germination And Seedling Herbivory, Katherine Overstrum
Herbivore Cues And Plant Damage-Associated-Compounds Jointly Alter Seed Germination And Seedling Herbivory, Katherine Overstrum
Open Access Master's Theses
While plant defense against herbivory is primarily thought to occur following attack, there is also evidence that plants can detect and respond to pre-attack cues. These cues include chemicals released from damaged conspecifics and kairomones, non-attack-related substances emitted by an herbivore that plants can detect and use to their benefit. It is unknown, however, whether or how plants react to the interaction of these pre-attack cues. We measured germination, growth, and herbivore susceptibility of B. nigra seedlings in an experiment that crossed the presence/absence of crushed B. nigra leaves with the presence/absence of mucus of a generalist herbivore, A. subfuscus …
Role Of Estrogen Receptor Alpha In Modulating The Circadian System In Female Mice, Victoria Alvord
Role Of Estrogen Receptor Alpha In Modulating The Circadian System In Female Mice, Victoria Alvord
Theses and Dissertations--Biology
Circadian rhythms are approximately 24-hour cycles of physiology and behavior. Circadian rhythms of eating, or meal timing, are linked to cardiometabolic dysfunction in humans. Mistimed eating, such as breakfast skipping and eating late at night, increases the risk of obesity, diabetes, and cardiovascular disease in humans. Likewise, disrupted eating rhythms cause obesity in mice. This dissertation investigates how estrogens regulate eating behavior rhythms and tissue clock timing in female mice. Chapter 1 reviews three key components critical to this work. The first is an overview of the field of chronobiology and the function of the circadian system. The second is …
The Rhesus Macaque Model Of Mycobacterium Avium Infection Reveals That Age-Related Disease Is Due In Part To Chronic Inflammation And Lung Microbial Dysbiosis, Ethan G. Napier
Theses and Dissertations--Microbiology, Immunology, and Molecular Genetics
Aging is associated with dysregulated immunity and increased susceptibility to infection, a phenomenon dubbed as immunosenescence and characterized by reduced naïve T and B cell pools, altered innate immune function, and chronic low-grade inflammation. Nontuberculous mycobacterial (NTM) pulmonary disease (NTMPD) is an increasingly relevant chronic lung infection that disproportionately affects older adults (65+ years) and immunocompromised individuals. However, the host factors underlying increased disease severity in aged patients remain poorly defined. Literature suggests that effective control of NTM relies on coordinated innate and adaptive immune responses, particularly macrophage activation and Th1 cytokine signaling. Using a rhesus macaque model that closely …
A Framework For Characterizing The Peripheral Immune Isonome Using Long-Read Single-Cell Rna Sequencing And Its Relevance To Neurological Disease, Patricia Hayes Doyle
A Framework For Characterizing The Peripheral Immune Isonome Using Long-Read Single-Cell Rna Sequencing And Its Relevance To Neurological Disease, Patricia Hayes Doyle
Theses and Dissertations--Neuroscience
Long-read single-cell RNA sequencing provides an opportunity to understand human health and disease at isoform resolution, revealing cellular diversity and disease mechanisms difficult to resolve with bulk or short-read methodologies.
Using a modified PIPseq workflow and computational pipeline adapted for Oxford Nanopore (ONT) sequencing, we profiled isoform usage across immune cells, integrating marker expression and isoform discovery, generating the largest long-read single-cell dataset of human immune cells from a single individual to date. We identified non-canonical protein-coding variants of GZMB and CD3G enriched in unexpected cell types. We also discovered novel transcripts from CMC1 and LYAR with cell-type-specific signatures that …
Expanding The Role Of Muscle Stem Cell Fusion In Muscle Under Hypertrophic Stimulus, Jensen Goh Zhong Sheng
Expanding The Role Of Muscle Stem Cell Fusion In Muscle Under Hypertrophic Stimulus, Jensen Goh Zhong Sheng
Theses and Dissertations--Physiology
Muscle stem cells (MuSCs) are a unique stem cell population that can activate in response to both injury and growth stimuli. Studies on muscle regeneration have shown MuSC activation follows a uniform progression through proliferation, differentiation, and fusion. Therefore, to determine whether MuSC replication is a prerequisite for differentiation under hypertrophic stimulus, I used a lineage-tracking mouse model (Pax7rtTA; TRE-H2B-GFP) to label MuSC nuclei and simultaneously tracked DNA synthesis via EdU incorporation. This dual-labeling approach allowed us to not only distinguish MuSC-derived nuclei but also demarcate which MuSC had proliferated prior to fusion. I then employed a mechanical …
Using Camera-Based Unmarked Spatial Capture-Recapture Modeling To Estimate Reintroduced Elk (Cervus Canadensis) Population Parameters And Distribution In Southeastern Kentucky, Claire Marie Muia
Theses and Dissertations--Forestry and Natural Resources
Estimation of population parameters is important for wildlife management decisions. Elk reintroduced to southeastern Kentucky experienced early irruptive population growth and are currently monitored using a statewide harvest-based statistical population reconstruction model (SPR) across the Kentucky Elk Restoration Zone (KERZ). Because the SPR model is spatially coarse and difficult to scale to the smaller management units comprising the KERZ, we conducted a spatially explicit capture-recapture study using a clustered camera-trapping array deployed for 10 weeks from June–August 2024 to estimate elk population parameters within Management Unit 4. Due to a lack of resights of GPS-marked elk, population parameters were estimated …
Between The Rails: Experiential Education And Its Impact On Compliance And Consistency In Racetrack Surface Management, Heather Mackenzie
Between The Rails: Experiential Education And Its Impact On Compliance And Consistency In Racetrack Surface Management, Heather Mackenzie
Theses and Dissertations--Community & Leadership Development
Recent regulatory requirements within the Thoroughbred racing industry have increased expectations for consistent collection and reporting of racetrack surface data. Despite clear standards, implementation in daily operations remains inconsistent, highlighting a gap between regulation, knowledge, and practice. This study examined the impact of an experiential education curriculum on racetrack personnel’s self-efficacy and reporting consistency.
Using a quantitative design, data were collected through pre- and post-surveys measuring self-efficacy and records of the number of days surface data were entered. Descriptive statistics, paired-samples t-tests, and effect size analyses were used. Results showed a statistically significant increase in self-efficacy (p < .001) with large effect sizes, indicating meaningful gains in confidence and comfortability. Reporting consistency did not show a statistically significant change (p = .885).
Overall, experiential education …
Understanding Knowledge And Perceptions Of The Beef Industry On A Land-Grant University Campus, Allison E. Reaves
Understanding Knowledge And Perceptions Of The Beef Industry On A Land-Grant University Campus, Allison E. Reaves
Theses and Dissertations--Community & Leadership Development
A well-researched phenomenon in the agricultural industry is the effects of constant innovation coupled with an increasing divide between producer and consumer. This issue has been presented as especially prevalent within animal agriculture and the beef industry, a predominant concern considering Kentucky’s agricultural commodities. This study (n = 31) utilized a mixed-methods approach to understand the knowledge, perceptions, and behavior of beef consumers on a land-grant university campus. Methodologies included Python’s DeepFace emotion recognition, semi-structured interviews, and the JMALI agricultural literacy assessment. Findings revealed participants to be below expected agricultural literacy levels of high school graduates (M=11), with no …
Hsp90 Inhibitor, At13387 Mitigates Chronic Lung Injury In Pre-Pubertal Mice: A Therapeutic Axis In Bronchopulmonary Dysplasia, Pavel A. Solopov, Christiana Dimitropoulou, John D. Catravas, Ruben M. L. Colunga Biancatelli
Hsp90 Inhibitor, At13387 Mitigates Chronic Lung Injury In Pre-Pubertal Mice: A Therapeutic Axis In Bronchopulmonary Dysplasia, Pavel A. Solopov, Christiana Dimitropoulou, John D. Catravas, Ruben M. L. Colunga Biancatelli
Bioelectrics Publications
Exposure to hydrochloric acid (HCl) can provoke severe chronic pulmonary injury. Children are particularly vulnerable due to their smaller airways, higher respiratory rate, and stronger inflammatory response; yet no countermeasures exist for HCl-induced chronic lung injury in the pediatric population. We have previously demonstrated the involvement of HSP90 during HCl-induced lung injury in pre-pubertal (p24) mice, who develop stronger persistent inflammation with higher NLRP3 inflammasome activation, but less pulmonary fibrosis compared to adults. Here, we tested the hypothesis that post-treatment with the second-generation HSP90 inhibitor AT13387 (Onalespib), administered subcutaneously beginning 24 h after HCl instillation, would prevent HCl-induced chronic lung …
Arkansas Corn And Grain Sorghum Performance Tests 2025, J. F. Carlin, J. P. Kelley, T. N. Spurlock, T. D. Swanson, R. D. Bond, J. C. Mccoy, C. J. Bulloch
Arkansas Corn And Grain Sorghum Performance Tests 2025, J. F. Carlin, J. P. Kelley, T. N. Spurlock, T. D. Swanson, R. D. Bond, J. C. Mccoy, C. J. Bulloch
Arkansas Agricultural Experiment Station Research Series
Report Statement This Arkansas Agricultural Experiment Station (AAES) publication summarizes variety trial research conducted by the Arkansas Crop Variety Improvement Program. Variety trial information presented here furthers the AAES mission of conducting research that benefits the citizens of Arkansas by expanding agricultural profitability and strengthening local and state economies. This information is not a recommendation or an endorsement of any product by the University of Arkansas System Division of Agriculture or AAES. Recommendations interpreted from this information are made and presented by the Arkansas Cooperative Extension Service.
Corn and grain sorghum performance tests are conducted each year in Arkansas by …
Adolescent Binge-Like Feeding And Neuroinflammation: Effects Of Intermittent Palatable Diet Access On Microglial Activation In The Brain In Adolescents, Jaimie T. Yu
CMC Senior Theses
Binge eating disorder (BED), one of the most common eating disorders in the United States (Definition & Facts for Binge Eating Disorder - NIDDK, n.d.), is characterized by recurrent episodes of consuming large quantities of food in a short period of time accompanied by a sense of loss of control. The intermittent access (INT) model reliably produces binge-like eating in adult rodents, with animals showing episodic hyperphagia upon time-limited access to a high-fat, high-sugar (HFHS) diet. In adult female rats, INT access produces elevated meal size and reduced satiety ratio relative to controls (Maske et al., 2020), and promotes microglial …
Microbial Community Structure In Global Soils, Matthew Jabro
Microbial Community Structure In Global Soils, Matthew Jabro
CMC Senior Theses
Soil harbors the most diverse microbial communities on Earth, yet whether predictable community types exist across biomes and whether taxonomic composition encodes habitat of origin remain open questions at global scale. This thesis addresses both questions by applying unsupervised clustering and supervised classification to transformed 16S ribosomal RNA (rRNA) amplicon profiles from two independent datasets: the global topsoil survey of Bahram et al. (193 samples) and the Earth Microbiome Project (EMP) soil subset of Thompson et al. (2,209 samples). Application of a sample clustering method based on a mixture of Gaussian Graphical Models (MixGGM) identified 19 clusters in the topsoil …