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Neural Patterns Reflect Semantic Representation In Novice Sign Language Learners, Megan E. Hillis

Dartmouth College Ph.D Dissertations

How do novice language learners represent semantic information in their new language? The extent to which languages are supported by distinct or overlapping neural representations in bilinguals has been the topic of much research, but less is known about how new knowledge is integrated into established representational networks, especially at the earliest stages of language acquisition. Furthermore, most investigations have compared languages which share a modality (spoken). Signed languages can provide insight into language unconfounded by perceptual qualities that spoken languages share. Chapter 1 presents an initial study in which hearing English-speaking non-signers learned a set of nouns in American …

A Qualitative Nmr And Histological Analysis Of Adipocere Formation In Different Aqueous Environments Using Sus Scrofa Models, Mia M. Sorrentino

Student Theses

Adipocere is a wax-like crust that has the potential to form over corpses in moist, humid, and anaerobic environments, preserving them in a process similar to that of mummification. The substance can be identified within 3-6 months postmortem and is characterized by the ratio of saturated fatty acids to unsaturated fatty acids. Palmitic acid and stearic acid are the most abundant in comparison to myristic and oleic acids. The goal of this study was to investigate factors affecting adipocere formation in different aqueous environments. Pork belly samples were submerged in water samples collected from different places around New York City …

Developing A Small Molecule To Inhibit Hsf1 Expression In Cancer And Evaluating Natural Genetic Variation In Small Molecule Toxicity., Michaela Kendal Foley

Theses and Dissertations

Each year cancer affects nearly 20 million people worldwide and genetic differences across populations can impact cancer onset and progression. Specifically, tumors with high levels of HSF1, the master regulator of the cytoprotective heat shock response (HSR), are correlated with poor patient outcomes in multiple cancers such as prostate, breast, and melanoma. Subsequently, the development of pharmacological inhibitors of HSF1 represents a promising strategy for anticancer therapeutics. Using a luciferase-based transcriptional reporter, two small molecule libraries were screened for inhibitors of HSF1 expression in human embryonic kidney cells, yielding ten compounds that decrease HSF1 expression. To identify if cancer lines …

Determining The Influence Of A Low-Head Dam On Macroinvertebrate Communities In The Bouie River, Natalie Santiago

Honors Theses

The Bouie River is a tributary of the Leaf River and belongs to the Pascagoula River watershed, the latter of which has no flow impediments in the form of sills or dams. The Bouie River has been heavily altered in the lower 10 river kilometers (rkm) from aggregate mining (creating a series of deep gravel pits) and the presence of an earthen and concrete low-head dam (sill) located 6 rkm from the mouth of the river. However, despite these alterations, the immediate stretch of river below the low-head dam is a known spawning habitat for diadromous fish species, including the …

Climate Prediction As An Adaptive Force-Multiplier: Reasons For Hope In A Rapidly Changing World, Matthew D. Laplante

All Graduate Theses and Dissertations, Fall 2023 to Present

It's not unreasonable to feel pessimistic about our future under climate change. But "believing the science" doesn't require you to accept that we are headed toward apocalypse. It is true that human-caused climate change is real, it is underway, and our societies face many increased risks because of it. But that's just part of what climate science tells us about our future world. This same field is responsible for the recent and rapid development of tools and techniques that permit the identification of patterns in our oceans and atmosphere that will aid us in making increasingly accurate predictions about climate—the …

High-Throughput Phenotyping Of Early Generation Small Grains Breeding Lines To Indirectly Select For Grain Yield, Dalton Jones

All Graduate Theses and Dissertations, Fall 2023 to Present

In small grains breeding programs, breeders aim to develop better varieties by selecting for important traits like grain yield. However, it takes many years before yield can be measured because several generations of selection are required to fix lines and increase sufficient seed for yield measurements. This process can be slow and expensive

High-throughput phenotyping (HTP) is a modern approach that can increase breeding efficiency by leveraging technology to quickly measure secondary traits which can be used to indirectly select for important traits in crop plants. For example, researchers can use cameras on unmanned aerial vehicles (UAVs, i.e., drones) to …

Analyzing Microalgae-Bacteria Population Changes In Response To Environmental Parameters For Improved Wastewater Treatment, Amanda M. Moravek

All Graduate Theses and Dissertations, Fall 2023 to Present

Microalgae are incredible organisms that have a variety of uses such as wastewater treatment, fertilizer, livestock feed, and bio-compound production. Microalgae require a light source and minimal nutrients space to proliferate, making them an environmentally friendly and sustainable option for such processes. The Sustainable Wastes-to-Bioproducts Engineering Center at Utah State University is developing and implementing a Rotating Algae Biofilm Reactor (RABR) to remove total nitrogen and phosphorous from the Central Valley Wastewater Reclamation Facility wastewater effluent. Harmful compounds such as nitrates and phosphates are metabolized by the microalgae and converted into useful bioproducts, resulting in a circular economy. These RABRs …

Seeding Rate, Planting Date, And Herbicides For Dormant Seeded Safflower In Utah, Rodney Daniel Nelson

All Graduate Theses and Dissertations, Fall 2023 to Present

Dryland crop production in the Intermountain West is largely limited by the amount of precipitation received. Increasing dryland safflower (Carthamus tinctorius L.) production yields in a semi-arid climate is possible with a dormant planting but is not well understood. A two-year (2020-22) project was designed to gain an understanding of the effects of variety, seeding rate, and planting date, on dormant seeded safflower. Chemical weed control options for safflower were also evaluated. One study, conducted at three Utah State University research farms near Blue Creek, Clarkston, and Kaysville, UT, evaluated four varieties, S-208, S-333, 7325 and Hybrid-446, seeded at …

Potamogeton Crispus Invasion: Impacts On Native Aquatic Plants And Associated Faunal Habitat, Meghan-Grace Slocombe

All Graduate Theses and Dissertations, Fall 2023 to Present

Aquatic invasive plants are non-native plants that invade a water body and displace native aquatic plants. Invasion depletes the native plant community's ability to provide ecosystem services, including improved water quality, decreased problematic algae, and increased animal habitat. The loss of these ecosystem services reduces the value of fishing, boating, and swimming opportunities in aquatic ecosystems. The potential changes in plant communities and services are particularly important at sites targeted for restoration because project goals typically include increasing ecosystem services, including wildlife habitat. Curly-leaf pondweed (Potamogeton crispus L.) is a problematic invasive species in North America. To better manage …

Seasonal And Temporal Influences On Successful Crossing Rates By Ungulates Of A North Utah Wildlife Overpass, Blake Ledbetter

All Graduate Theses and Dissertations, Fall 2023 to Present

Encroachment of human infrastructure fragments wild landscapes and introduces a suite of negative impacts for humans and wildlife. In Utah, roadways threaten migratory ungulates by creating a barrier to movements and preventing access to seasonal migration routes. To mitigate these conflicts, state transportation agencies often install wildlife crossing structures to allow animals to safely cross over or under roadways. Selecting the proper crossing structure requires consideration of the species of interest, landscape, location, and structural dimensions. Often there is balance between the optimal location, the dimensions of the crossing structures, and what is feasible given the landscape. In 2018, the …

Uv-A Light And Heat-Activated Antimicrobial And Biodegradable Materials For Food Packaging And Preservation, Michael J. Bodily

All Graduate Theses and Dissertations, Fall 2023 to Present

Current food packaging materials are often non-biodegradable and harmful for ingestion, which poses a threat to the environment and public health. Thus far, the dangers of microbial contamination of food on human health have outweighed the risks associated with using these conventional packaging plastics. A possible solution to these issues is to use a combination of innovative materials and microbial inactivation methods that can potentially both reduce plastic waste and combat harmful microorganisms. In this study, two antimicrobial, biodegradable composites were developed and tested for their ability to inactivate two types of bacterium, Escherichia coli K12 and Listeria innocua, …

Disentangling Factors Contributing To Population Performance Of Zion Bighorn Sheep, Ian Montgomery

All Graduate Theses and Dissertations, Fall 2023 to Present

Bighorn sheep populations across the western United States face increasing challenges from habitat loss, disease, and predation. In Zion National Park and surrounding areas, survey-based estimates indicate that the desert bighorn sheep population declined from over 800 individuals in 2018 to fewer than 500 in 2021. Understanding what drives these population changes is critical for effective wildlife management and conservation. This research examined key factors influencing population growth and individual survival to inform strategies for recovery in this bighorn population.

First, we analyzed which vital rates contributed most to population trends by estimating survival and reproduction rates from ground and …

Screening Of A Diversity Of Legumes And Non-Legumes Forb Species At Five Strategic Locations Across Utah For The Development Of Smart Foodscapes, Surbhi Verma

All Graduate Theses and Dissertations, Fall 2023 to Present

Grass-dominated rangelands in the Western United States often lack sufficient protein for pregnant cows after grasses mature in mid- summer, leading ranchers to rely on expensive feed supplements such as protein cubes or alfalfa hay. The goal of this study was to screen 27 perennial legume and forb species with the potential to remain green into late summer and provide sufficient protein to supplement cows on grass-dominated rangeland. Three experiments were carried out to understand germination of species, plant establishment and persistence at five Utah locations, and agronomic characteristics. The seed of five hard-to-germinate species were studied for the ability …

Optimizing Nutrient Recycling To Achieve Zero–Discharge Management For Controlled Environment Agriculture, Noah James Langenfeld

All Graduate Theses and Dissertations, Fall 2023 to Present

Controlled environment agriculture (CEA) allows for human control of one or more environmental factors affecting crop production. Optimizing nutrient management in such systems allows for translation and predictions of sustainable management strategies in the field. These systems will be used to supply fresh food as public and private space agencies are planning to send humans to the Moon and Mars in the near future. Food resupply becomes increasingly difficult as the distance from Earth increases. Plants can be grown off-Earth as a food source, but their growth must be carefully managed to ensure long-term sustainability. I describe a model used …

Effects Of Plant Biostimulants On Onion Growth And Production Under Greenhouse And Field Conditions, Prakriti Nepal

All Graduate Theses and Dissertations, Fall 2023 to Present

The escalating impact of climate change on agricultural production underscores the need to investigate sustainable crop enhancement methods. This research explores the use of plant biostimulants to grow onion (Allium cepa L.) under varying environmental conditions. In the initial germination and greenhouse screening, seven biostimulants were tested on ‘Vaquero’ onion seeds: three bacterial products (Continuum, Spectrum DS, and Tribus Original), two mycorrhizal products (Mighty Mycorrhizae and Myco Apply), one seaweed extract product (Seaweed), and one product containing humic acid (Huma Pro 16). Mighty Mycorrhizae, Continuum, and Myco Apply supported faster germination, while seeds treated with Spectrum and Seaweed took …

Clostridioides Difficile In Feral Horse Populations In Australia, Natasza M.R. Hain-Saunders, Daniel R. Knight, Andrea Harvey, Mieghan Bruce, Brian A. Hampson, Thomas V. Riley

Research outputs 2022 to 2026

Clostridioides difficile is a known cause of diarrhea and colitis in human and non-human animals. While C. difficile is regularly isolated from domesticated horses, little is known about its prevalence in wild or feral populations. In Australia, the horse population encompasses a mix of both domesticated and feral animals, with the feral population of 400,000 estimated to be the largest in the world. This study investigated the presence and characteristics of C. difficile in Australian feral horses and evaluated their potential as a source or reservoir of C. difficile in the wider community. Fecal samples (n = 380) were collected …

Revised Phylogeography Of The Common Brushtail Possum (Trichosurus Vulpecula) Reveals New Insights Into Genetic Structure Across Australia, Shelby C. Middleton, Robert A. Davis, Kenny J. Travouillon, Anna J.M. Hopkins, Harriet R. Mills, Linette S. Umbrello

Research outputs 2022 to 2026

Understanding genetic relationships within species is essential for identifying distinct genetic lineages and informing conservation strategies, particularly for species with fragmented or widespread geographic distributions. One such widespread species that has suffered declines across Australia, despite remaining common in some areas, is the common brushtail possum (Trichosurus vulpecula), a nocturnal and arboreal marsupial. Previous genetic studies on brushtail possums had limited sampling, which has precluded a comprehensive assessment of the relationships within the species and genus. Using both single nucleotide polymorphism markers and the mitochondrial cytochrome b gene, this study employed phylogenetics, ancestry coefficients, and tested genetic differentiation, to examine …

Ecological Specialisation Of Reef Fishes Peaks In Global Biodiversity Hotspots, Zoé Delecambre, Renato A. Morais, Alexandre C. Siqueira, Emma Paul Costesec, Caroline E. Dubé, Sergio R. Floeter, Alan M. Friedlander, Fabien Leprieur, Yves Letourneur, Lucas T. Nunes, Jordan M. Casey, Valeriano Parravicini

Research outputs 2022 to 2026

Aim: The role of ecological specialisation in shaping biogeographic and evolutionary patterns remains unresolved. To date, few studies have quantitatively examined consumer niche breadth at a global scale. We describe global biogeographic and diversification patterns of specialisation, measured using trophic and thermal niches, for a highly diverse assemblage of consumers: reef fishes. First, we investigated the confluence of specialisation with global biogeographic patterns in species richness and reef area. Then, we tested whether these patterns could be explained by differences in diversification rates and geographic ranges. Location: Tropical reefs across the globe. Time Period: Present. Major Taxa Studied: Reef fishes. …

Can A Ceh-27/Nkx2.1 Transgene Rescue Ceh-27 Neurodevelopmental Defects?, Meryl Gilmore, Martin L. Hudson

Symposium of Student Scholars

When the development of an organism’s nervous system is interrupted or altered, it can significantly impact that organism’s ability to survive and function properly. In our lab, we use a species of nematode called Caenorhabditis elegans as a model organism to characterize the roles of important transcription factors in human neurodevelopmental disorders such as attention deficit hyperactivity disorder (ADHD). Utilizing C. elegans makes analyzing this process in a lab very easy for many reasons; they are very small, have a rapid life cycle, invariant cell lineage, transparent bodies, and most importantly, around 80% of their genes have human orthologs. In …

Crónicas De Gastronomía Ancestral De La Provincia De Ubaté (Cundinamarca), Johanna Andrea Gil Palacios, Nancy Milena Valiente Triana, Nohora Liliana Agudelo Rodríguez, Carlos Alfonso López Urquina, Cristian Ballén Guarín, John Henry Vásquez Calderón

Institucional

Este libro es un viaje maravilloso que conduce al lector a comprender la estrecha relación entre territorio y gastronomía. Cada accidente geográfico representa un reto de sus pobladores que potencia su creatividad para sobrevivir e implica el esfuerzo para que broten frutos que se puedan llevar a la mesa, en sendas preparaciones que se van heredando entre generaciones. Las personas cuentan llenas de orgullo las gestas que han vivido en torno a la comida, las reuniones familiares, las fiestas patronales, y las convierten en la mejor vitrina de su identidad y la celebración de las cosechas. Es un verdadero placer …

Assessing The Behavioral Impact Of Pyridostigmine Bromide In Rats, Noah A. Martin

Honors Theses

Pyridostigmine bromide (PB) is an organophosphate (OP) nerve agent prophylactic used to protect warfighters against chemical warfare agents. OPs inhibit the neural enzyme acetylcholinesterase (AChE) in the brain. This leads to the buildup of acetylcholine, causing respiratory failure, seizures, and death. PB functions by inhibiting ~30% of peripheral AChE temporarily, protecting the enzymes so that the body is able to restore sufficient cholinergic function post-exposure. PB does not cross the blood-brain barrier, though it may still indirectly affect toxicity in the brain due to repeated AChE inhibition throughout treatment, or by inhibition of non-target ChE’s in the blood. The aim …

Gonadal Absence Of Ceh-22: Degradation Of Ceh-22 In The Gonads Of Caenorhabditis Elegans, Andreya C. White

Undergraduate Theses

The reproductive system of hermaphrodite Caenorhabditis elegans (C. elegans) comprises two gonadal arms, each with a terminating distal tip cell (DTC), connected by a common uterus. The DTC has two functions: leader and niche. In C. elegans, ceh-22/nkx2,5 has been found to work together with Wnt signaling to determine the fates of the DTC (Lam et al., 2006). This is an indication that ceh-22 aids in the specification of DTCs. Our research aims to determine the specific function of ceh-22 in the gonad of both male and hermaphrodite C. elegans. This will be accomplished by observing …

Maternal Dietary, Nutritional Status, And Its Association With Low-Birth Weight: A Scoping Review, Tri Siswati, Devi Septia Ningrum, Adinda Safitri, Almira Sitasari

Indonesian Journal of Public Health Nutrition (IJPHN)

Maternal diet and nutritional status during pregnancy influence birth outcomes. This review article aims to synthesize key studies examining the relationship between maternal dietary intake, nutritional status, and the occurrence of low birth weight (LBW). This study applies a scoping review from PubMed and Google Scholar (2018–2023). Observational and experimental studies were included. Articles met the criteria if they involved pregnant women aged 17+, human studies, full-text availability, and were in English or Indonesian. Fourteen studies met the inclusion criteria and were analyzed. The findings revealed that maternal intake of essential macronutrients, including energy and protein, along with key micronutrients …

Different Effects Between Trigeminal Sensory And Vagal Visceral Input On Salivary Gland Blood Flow, Ratna Ramadhani, Toshiya Sato, Hisayoshi Ishii

Journal of Dentistry Indonesia

Objective: The purpose of the present study was to evaluate the different effects of trigeminal sensory and vagal-visceral inputs on blood flow (BF) in the submandibular gland (SMG). Methods: Ten to eleven-week-old Wistar rats were anesthetized with urethane (1.0 g/kg) and artificially ventilated. The femoral artery was cannulated for systemic arterial blood pressure (SABP) measurement. The cervical sympathetic trunk (CST) on both sides and the cervical vagus nerve (CVN) on the right side were cut before the stimulation of the left abdominal vagus nerve (AVN). The CVN and lingual nerve (LN) were stimulated after cutting the CST and CVN. AVN, …

Neurotransmitter Power Plays: The Synaptic Communication Nexus Shaping Brain Cancer, Jayanta Mondal, Jason T Huse

Faculty, Staff and Student Publications

Gliomas and brain metastases are notorious for their dismal prognosis and low survival rates, a challenge exacerbated by our incomplete grasp of the complex dynamics that govern brain cancers. Recently, a groundbreaking paradigm shift has emerged, highlighting the crucial role of synaptic communication between neurons and brain tumor cells in reshaping neuronal signaling to favor tumor growth. This review delves into the pivotal interplay of synaptic mechanisms, focusing on excitatory glutamatergic and inhibitory GABAergic pathways. Glutamatergic synapses utilize glutamate to propagate excitatory signals, while GABAergic synapses employ gamma-aminobutyric acid (GABA) to inhibit neuronal firing. Glutamatergic signaling can be broadly classified …

Can Assessment Of Morphometrics Correctly Predict Species In Madtoms?, Harley C. Walden

ATU Scholars Symposium

Species delineation is commonly achieved through genetic analyses, but the utility of morphometrics as an alternative method remains unclear. This study investigates whether morphometric measurements can effectively differentiate species in madtoms (Noturus spp.). A total of 10 morphometric traits were measured from 50 individuals each of three madtom species: the Slender Madtom (Noturus exilis), the Black River Madtom (Noturus maydeni), the Ozark Madtom (Noturus albater), the Ouachita Madtom (Noturus lachneri) and the Freckled Madtom (Noturus nocturnus). Random forest modeling was employed to identify which morphometric variables most accurately distinguish between …

Distribution Of Mussels In Two Intermittent Upland Streams Of The Arkansas Valley Ecoregion, Aaron A. Brady, Seth Drake, Zach Crain, Kendall Moles

ATU Scholars Symposium

Freshwater mussels are facing an increasing need for conservation due to their declining populations. More data is needed on mussel distributions, especially in tributaries of large rivers to properly conserve and restore populations. Big Shoal Creek and Little Shoal Creek are two upland-tributaries of the Arkansas River (Lake Dardanelle) in which no records exist for freshwater mussel populations. We addressed this knowledge gap by sampling a total of 9 sites in Little Shoal Creek and 18 sites in Big Shoal Creek to determine the abundance and distribution of mussels in these streams. Mussels were sampled using a timed search approach. …

Influence Of Biting Flies On The Growth And Condition Of Nestling Eastern Bluebirds, Ella Grace Bollinger

ATU Scholars Symposium

Habitat alteration and climate change are expected to increase the range, abundance, and season length of ectoparasites and the pathogens they carry. This is particularly concerning for nestling birds that are relatively naked and immobile, making them vulnerable to attacks by biting flies such as blackflies and mosquitoes. Despite the ubiquity of biting flies and the challenges they pose to nestlings, studies investigating their association with breeding birds remain rare. To address this, we propose a series of observational and experimental field studies with Eastern Bluebirds (Sialia sialis) to investigate the attraction of biting flies to active nests …

Using Guano To Determine Ozark Big-Eared Bat Cave Occupancy In Arkansas​, Lark E. Sybrant

ATU Scholars Symposium

The Ozark big-eared bat (Corynorhinus townsendii ingens) is endangered in Arkansas and is known to have small populations, range restrictions, and specific habitat requirements in the Ozark-St. Francis National Forest. Beyond their known range, there are other potentially suitable areas that have not been confirmed. We aim to test whether the non-invasive genetic analysis of guano samples can identify Ozark big-eared bat cave use and expand their known range. Additional locations need to be surveyed to ensure site protection, as unknown caves are susceptible to human disturbance and damage. Twenty-five sites were surveyed at the southeastern extent of their known …

Della Protein And Cbl-Cipk Signaling Pathway As Candidates For Genetic Engineering, Nathan F. Surles

ATU Scholars Symposium

No abstract provided.