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Modulation Of Mechanical Stress Mitigates Anti-Dsg3 Antibody-Induced Dissociation Of Cell–Cell Adhesion, Xiaowei Jin, Jordan Rosenbohm, Eunju Kim, Amir Monemian Esfahani, Kristina Seiffert-Sinha, James K. Wahl Iii, Jung Yul Lim, Animesh A. Sinha, Ruiguo Yang Mar 2021

Modulation Of Mechanical Stress Mitigates Anti-Dsg3 Antibody-Induced Dissociation Of Cell–Cell Adhesion, Xiaowei Jin, Jordan Rosenbohm, Eunju Kim, Amir Monemian Esfahani, Kristina Seiffert-Sinha, James K. Wahl Iii, Jung Yul Lim, Animesh A. Sinha, Ruiguo Yang

Department of Mechanical and Materials Engineering: Faculty Publications

It is becoming increasingly clear that mechanical stress in adhesive junctions plays a significant role in dictating the fate of cell–cell attachment under physiological conditions. Targeted disruption of cell–cell junctions leads to multiple pathological conditions, among them the life-threatening autoimmune blistering disease pemphigus vulgaris (PV). The dissociation of cell–cell junctions by autoantibodies is the hallmark of PV, however, the detailed mechanisms that result in tissue destruction remain unclear. Thus far, research and therapy in PV have focused primarily on immune mechanisms upstream of autoantibody binding, while the biophysical aspects of the cell– cell dissociation process leading to acantholysis are less …

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Solid State Synthesis And Characterization Of Apatite Based Ceramic Waste Form For The Immobilization Of Radioactive Iodine, Md Imdadul Islam Mar 2021

Solid State Synthesis And Characterization Of Apatite Based Ceramic Waste Form For The Immobilization Of Radioactive Iodine, Md Imdadul Islam

LSU Doctoral Dissertations

The growing demand for nuclear power in the United States and worldwide is accountable for addressing the major concern of radioactive waste, involving the technical challenges of maintaining the nuclear fuel cycle and immobilizing high-level wastes for safe disposal in geological storage. The appropriate selection of waste forms for spent nuclear fuel such as fission products and radionuclides can be effective means for a feasible and sustainable nuclear fuel cycle. But highly volatile radionuclides such as iodine (129) are of specific concern due to its extraordinary long half-life (15.7 million years). Due to its poor solubility and high volatility at …

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Changes In Wetland Soil Processes And Ecosystem Functions Six Years After Marsh Creation In Barataria Bay, Louisiana, Erol R. Knaus Mar 2021

Changes In Wetland Soil Processes And Ecosystem Functions Six Years After Marsh Creation In Barataria Bay, Louisiana, Erol R. Knaus

LSU Master's Theses

Louisiana contains about 40% of the conterminous United States coastal and estuarine wetlands but also has the highest rates of wetland loss at around 80% of the total. Approximately 4,900 km2 of coastal land in Louisiana has been lost since 1930. Our study location, Barataria Bay, has one of the highest coastal wetland erosion rates in the nation, at ∼41 km2 per year; and therefore, is a high priority for wetland restoration activities. In 2014, sandy sediment dredged from the bed of the Mississippi River was placed in Barataria Bay as part of a restoration effort. Samples were …

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Human-Robot Collaboration For Effective Bridge Inspection In The Artificial Intelligence Era, Ruwen Qin Mar 2021

Human-Robot Collaboration For Effective Bridge Inspection In The Artificial Intelligence Era, Ruwen Qin

INSPIRE Archived Webinars

Advancements in sensor, Artificial Intelligence (AI), and robotic technologies have formed a foundation to enable a transformation from traditional engineering systems to complex adaptive systems. This paradigm shift will bring exciting changes to civil infrastructure systems and their builders, operators and managers. Funded by the INSPIRE University Transportation Center (UTC), Dr. Qin’s group investigated the holism of an AI-robot-inspector system for bridge inspection. Dr. Qin will discuss the need for close collaboration among the constituent components of the AI-robot-inspector system. In the workplace of bridge inspection using drones, the mobile robotic inspection platform rapidly collected big inspection video data that …

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Foot Contact Dynamics And Fall Risk Among Children Diagnosed With Idiopathic Toe Walking, Rahul Soangra, Michael Shiraishi, Richard Beuttler, Michelle Gwerder, Lou Anne Boyd, Venkatesan Muthukumar, Mohamed Trabia, Afshin Aminian, Marybeth Grant-Beuttler Mar 2021

Foot Contact Dynamics And Fall Risk Among Children Diagnosed With Idiopathic Toe Walking, Rahul Soangra, Michael Shiraishi, Richard Beuttler, Michelle Gwerder, Lou Anne Boyd, Venkatesan Muthukumar, Mohamed Trabia, Afshin Aminian, Marybeth Grant-Beuttler

Electrical & Computer Engineering Faculty Research

Children that are diagnosed with Idiopathic Toe walking (cITW) are characterized by persistent toe-to-toe contacts. The objective of this study was to explore whether typical foot contact dynamics during walking predisposes cITW to a higher risk of falling. Twenty cITW and age-matched controls performed typical and toe walking trials. The gait parameters related to foot contact dynamics, vertical force impulses during stance, slip, and trip risk were compared for both groups. We found that cITW manifest less stable gait and produced significantly higher force impulses during push-off. Additionally, we found that cITW had a higher slip-initiation risk that was associated …

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Polymeric Nanovectors Incorporated With Ganciclovir And Hsv-Tk Encoding Plasmid For Gene-Directed Enzyme Prodrug Therapy, Alicia J. Sawdon, Jun Zhang, Sarah Peng, Esmael M. Alyami, Ching An Peng Mar 2021

Polymeric Nanovectors Incorporated With Ganciclovir And Hsv-Tk Encoding Plasmid For Gene-Directed Enzyme Prodrug Therapy, Alicia J. Sawdon, Jun Zhang, Sarah Peng, Esmael M. Alyami, Ching An Peng

Michigan Tech Publications, Part 1

In the area of gene-directed enzyme prodrug therapy (GDEPT), using herpes simplex virus thymidine kinase (HSV-tk) paired with prodrug ganciclovir (GCV) for cancer treatment has been extensively studied. It is a process involved with two steps whereby the gene (HSV-tk) is first delivered to malignant cells. Afterward, non-toxic GCV is administered to that site and activated to cytotoxic ganciclovir triphosphate by HSV-tk enzyme expressed exogenously. In this study, we presented a one-step approach that both gene and prodrug were delivered at the same time by incorporating them with polymeric micellar nanovectors. GCV was employed as an initiator in the ring-opening …

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Leveraging Natural Language Processing To Mine Issues On Twitter During The Covid-19 Pandemic, Ankita Agarwal, Preetham Salehundam, Swati Padhee, William Romine, Tanvi Wright State University - Main Campus Mar 2021

Leveraging Natural Language Processing To Mine Issues On Twitter During The Covid-19 Pandemic, Ankita Agarwal, Preetham Salehundam, Swati Padhee, William Romine, Tanvi Wright State University - Main Campus

Computer Science and Engineering Faculty Publications

The recent global outbreak of the coronavirus disease (COVID-19) has spread to all corners of the globe. The international travel ban, panic buying, and the need for self-quarantine are among the many other social challenges brought about in this new era. Twitter platforms have been used in various public health studies to identify public opinion about an event at the local and global scale. To understand the public concerns and responses to the pandemic, a system that can leverage machine learning techniques to filter out irrelevant tweets and identify the important topics of discussion on social media platforms like Twitter …

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Alternative View Of Oxygen Reduction On Porous Carbon Electrocatalysts: The Substance Of Complex Oxygen-Surface Interactions, Giacomo De Falco, Marc Florent, Jacek Jagiello, Yongqiang Cheng, Luke L. Daemen, Anibal J. Ramirez-Cuesta, Teresa J. Bandosz Mar 2021

Alternative View Of Oxygen Reduction On Porous Carbon Electrocatalysts: The Substance Of Complex Oxygen-Surface Interactions, Giacomo De Falco, Marc Florent, Jacek Jagiello, Yongqiang Cheng, Luke L. Daemen, Anibal J. Ramirez-Cuesta, Teresa J. Bandosz

Publications and Research

Electrochemical oxygen reduction reaction (ORR) is an important energy-related process requiring alternative catalysts to expensive platinum-based ones. Although recently some advancements in carbon catalysts have been reported, there is still a lack of understanding which surface features might enhance their efficiency for ORR. Through a detailed study of oxygen adsorption on carbon molecular sieves and using inelastic neutron scattering, we demonstrated here that the extent of oxygen adsorption/interactions with surface is an important parameter affecting ORR. It was found that both the strength of O2 physical adsorption in small pores and its specific interactions with surface ether functionalities in the …

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Investigating The Novel Role Of Dextromethorphan In Mitigating Oxidative Stress Induced Changes In Retinal Pigment Epithelial Cells (Rpe), Zeinab A. Mohamed Mar 2021

Investigating The Novel Role Of Dextromethorphan In Mitigating Oxidative Stress Induced Changes In Retinal Pigment Epithelial Cells (Rpe), Zeinab A. Mohamed

USF Tampa Graduate Theses and Dissertations

Oxidative stress contributes to the degeneration of retinal pigment epithelial (RPE) cells and photoreceptors that lead to the dry form of age-related macular degeneration. Activation of N-Methyl-D-aspartate (NMDA) receptors contributes to the increase of free radicals that induce oxidative stress-induced changes. Our study investigates if Dextromethorphan, an NMDA receptor antagonist, reverses oxidative stress-induced changes in RPE. We used Paraquat and H2O2 as oxidative stress-inducing agents to induce oxidative damage in human ARPE-19 cells. To illustrate the change in cell viability and measure the apoptosis of ARPE-19 cells from oxidative damage, we performed MTT assay and Annexin V-DAPI flow cytometry analysis. …

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Passive Nitrifying Biofilters For Onsite Treatment Of Saline Domestic Wastewater, Daniel Arnulfo Delgado Mar 2021

Passive Nitrifying Biofilters For Onsite Treatment Of Saline Domestic Wastewater, Daniel Arnulfo Delgado

USF Tampa Graduate Theses and Dissertations

The infrastructure to support the growing world population has polluted many water bodies with nitrogen from urban and agricultural runoff and failing wastewater systems, such as improperly sited and maintained septic systems. Septic systems present a low energy and maintenance option to treat domestic wastewater and is a treatment option that can be done far from a centralized grid. This further reduces cost, maintenance, and energy as it reduces the need to build and maintaining sewage piping and the infrastructure to move the water longer distances. However, these systems tend to fail when their upkeep is left to homeowners that …

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Resource And Energy Recovery From Wastewater Using Advanced Bioelectrochemical Systems, Sidan Lu Mar 2021

Resource And Energy Recovery From Wastewater Using Advanced Bioelectrochemical Systems, Sidan Lu

LSU Doctoral Dissertations

Water pollution and energy depletion are two critical issues in the world that limit the sustainable development of human society. In this study, several advanced (photo) bioelectrochemical systems (BESs) were proposed for effective energy (electricity and H2) and nutrients (N and P) recovery from wastewater, solar energy, seawater, and river water. The first study demonstrated high effectiveness of a novel resource-recovery microbial fuel cell (RRMFC) for wastewater treatment and nutrient recovery from synthetic urine-containing wastewater. Over one cycle (∼3 days), 99% of urea, 97% of COD, 99% of histidine, 91% of creatinine, 99% of sodium acetate, 98% of …

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Women’S Perceptions Of The Aviation Workplace: An Exploratory Study, Lindsay Stevenson, Haydee Cuevas, Katya K. Rivera, Katie Kirkpatrick, Marisa Aguiar, Jorge L. D. Albelo Mar 2021

Women’S Perceptions Of The Aviation Workplace: An Exploratory Study, Lindsay Stevenson, Haydee Cuevas, Katya K. Rivera, Katie Kirkpatrick, Marisa Aguiar, Jorge L. D. Albelo

Publications

The purpose of this exploratory study was to garner a better understanding of the following research question: What factors may contribute to women’s retention in aviation occupations in the United States? The Aviation Occupation Survey was developed drawing from the published literature in organizational retention and diversity in aviation to explore this research question. The survey consisted of 50 Likert-scale items on nine subjects related to career retention. A total of 188 participants (women = 70, men = 118) completed the survey. Results revealed similarities between women and men on perceptions about numerous aspects of their workplace, particularly job satisfaction, …

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Wavefront-Selective Fano Resonant Metasurfaces, Adam C. Overvig, Andrea Alù Mar 2021

Wavefront-Selective Fano Resonant Metasurfaces, Adam C. Overvig, Andrea Alù

Advanced Science Research Center

Fano resonances are conventionally understood as sharp spectral features with selectivity in the momentum-frequency domain, implying that they can be excited only by plane waves with specific frequencies and incident angles. We demonstrate that Fano resonances can be made generally selective in the space-frequency domain. They can be tailored to resonate only when excited by a frequency, polarization, and wavefront of choice. This generalization reveals that Fano systems are characterized by eigenwaves that scatter to their time-reversed image upon reflection. Although in conventional Fano systems this trivially occurs for normally incident plane waves, we show that, in general, the selected …

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Ion Pairing And Dielectric Decrement In Glycosaminoglycan Brushes, James D. Sterling, Wenjuan Jiang, Wesley M. Botello-Smith, Yun L. Luo Mar 2021

Ion Pairing And Dielectric Decrement In Glycosaminoglycan Brushes, James D. Sterling, Wenjuan Jiang, Wesley M. Botello-Smith, Yun L. Luo

Business and Information Technology Faculty Research & Creative Works

Cell−surface polysaccharides are essential to many aspects of physiology, serving as a highly conserved evolutionary feature of life and as an important part of the innate immune system in mammals. Here, as simplified biophysical models of these sugar coatings, we present results of molecular dynamics simulations of hyaluronic acid and heparin brushes that show important effects of ion pairing, water dielectric decrease, and coion exclusion. As in prior studies of macromolecular crowding under physiologically relevant salt concentrations, our results show equilibria with electroneutrality attained through screening and pairing of brush anionic charges by monovalent cations at the atomistic detail. Most …

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Utilizing Digital Image Processing And Two‑Source Energy Balance Model For The Estimation Of Evapotranspiration Of Dry Edible Beans In Western Nebraska, Wei‑Zhen Liang, Isabella Possignolo, Xin Qiao, Kendall Dejonge, Suat Irkmak, Derek M. Heeren, Daran Rudnick Mar 2021

Utilizing Digital Image Processing And Two‑Source Energy Balance Model For The Estimation Of Evapotranspiration Of Dry Edible Beans In Western Nebraska, Wei‑Zhen Liang, Isabella Possignolo, Xin Qiao, Kendall Dejonge, Suat Irkmak, Derek M. Heeren, Daran Rudnick

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Having an accurate yet simple method to estimate crop evapotranspiration ( ETC) is a vital component of reliable irrigation scheduling. In this study, two versions of the two-source energy balance (TSEB) model: the TSEB model with the Priestley–Taylor equation (TSEB-PT) and the Penman–Monteith equation (TSEB-PM), were used to estimate ETC of dry edible beans in western Nebraska. Compared with previous studies, this study is unique in that a Visual Basic software—Crop Canopy Image Analyzer (CCIA) was developed to process digitally captured RGB canopy images to obtain necessary canopy cover (CC) parameters for the TSEB models such as …

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Engineering Cell-Free Protein Expression Systems For Biotherapeutics And Biosensing, John Porter Hunt Mar 2021

Engineering Cell-Free Protein Expression Systems For Biotherapeutics And Biosensing, John Porter Hunt

Theses and Dissertations

Therapeutic proteins have become a cornerstone of modern medicine since the FDA approval of recombinant human insulin in 1982. Likewise, biosensors transform chemical detection and disease diagnostics by identifying biomarkers, chemical contaminants, and infective agents. Long-standing methods for creating therapeutics and biosensors employ whole cells such as Escherichia coli (E. coli). Alternatively, cell-free protein synthesis (CFPS) employs the enzymatic reactions necessary for protein production and biosensing within a cell, but in an engineered reactor environment facilitating unprecedented access to and control over biochemical machinery, preservation by cryodesiccation for portable deployment, and functionality in cytotoxic applications. This dissertation reports advances in …

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Mars Reconnaissance: Civil Engineering Advances For Human Exploration, Laurent Sibille, Robert W. Moses, Robert P. Mueller, Michelle A. Viotti, Michelle M. Munk, Paul J. Van Susante, Et. Al. Mar 2021

Mars Reconnaissance: Civil Engineering Advances For Human Exploration, Laurent Sibille, Robert W. Moses, Robert P. Mueller, Michelle A. Viotti, Michelle M. Munk, Paul J. Van Susante, Et. Al.

Michigan Tech Publications, Part 1

No abstract provided.

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Photoluminescent Nanomaterials For Biosensing And Single Cell Analysis Applications, Khashayar Ramezani Bajgiran Mar 2021

Photoluminescent Nanomaterials For Biosensing And Single Cell Analysis Applications, Khashayar Ramezani Bajgiran

LSU Doctoral Dissertations

The bioanalytical industry is projected to generate $36 billion by 2025, with the United States currently holding 80.9% of the consumers’ market. Among the bioanalytical platforms, point-of-care (POC) and point-of-use diagnosis (POU) have gained a lot of attention due to their emphasis on decentralized testing and providing low-cost solutions in resource-limited regions. While Traditional bioanalytical tools such as enzyme-linked immunosorbent assay and flow cytometry can sensitively detect biomolecules and screen single-cell response, they suffer from multiple drawbacks such as the high cost of antibodies and time-intensive procedures, which limit their ability to expand to POC/POU applications. Rapid developments in microtool …

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Fabrication And Characterization Methods Of Self-Cleaning Coatings For Solar Panels Application, Mohammed Khaleel M Alhussain Mar 2021

Fabrication And Characterization Methods Of Self-Cleaning Coatings For Solar Panels Application, Mohammed Khaleel M Alhussain

USF Tampa Graduate Theses and Dissertations

Transparent self-cleaning coatings with superhydrophobic and superhydrophilic behavior are of great interest in a wide range of industrial applications such as automotive, solar panels, windows, and optical devices. Each has its uses, properties, and characteristics. For the use of these coatings on solar panels, certain features are important in maintaining the efficiency of the panels in different weather conditions and reducing the operation and maintenance cost, such as self-cleaning, high transparency, antifouling, anti-fogging, and anti-icing. Herein, we have investigated the fabrication of self-cleaning coatings using two simple methods and ways to improve their characteristics. In the first method, a hydrophobic …

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An Improved Clipped Sub-Histogram Equalization Technique Using Optimized Local Contrast Factor For Mammogram Image Analysis, Nurshafira Hazim Chan Mar 2021

An Improved Clipped Sub-Histogram Equalization Technique Using Optimized Local Contrast Factor For Mammogram Image Analysis, Nurshafira Hazim Chan

Student Works (2020-2029)

Mammography has been known worldwide as the most common imaging modalities utilized for early detection of breast cancer. The mammographic images produced are in greyscale, however they often produced poor contrast images, non-uniform illumination, and the image often contain artefacts and noise. These limitations can be overcame during the pre-processing stage by improving the image enhancement process. Therefore, in this research an optimized enhancement framework is developed where the local contrast factor is manipulated to preserve details of the image. This technique aims to improve the overall image visibility without altering histogram of the original image, which will affect the …

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Unconventional Agriculture: An Exploration Of Hydroponics And Aquaponics And Their Role As A Solution To Food Scarcity, Kai Meacham Mar 2021

Unconventional Agriculture: An Exploration Of Hydroponics And Aquaponics And Their Role As A Solution To Food Scarcity, Kai Meacham

Honors Program: Senior Projects (Public)

Unconventional agriculture includes methods of farming that are defined by unique farming practices and a focus on sustainability. Unconventional agriculture can take many forms, including hydroponic systems and aquaponic systems. These two systems are unique in the sense that they are soilless methods of growing plants. Both of these systems require careful monitoring because they do not have soil to act as a buffer and help maintain normal levels. Though these two systems are very similar they have some key differences in how they function, which ultimately leads to differing advantages and disadvantages of both systems. Additionally, these systems have …

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Are Terrorist Networks Just Glorified Criminal Cells?, Elie Alhajjar, Ryan Fameli, Shane Warren Mar 2021

Are Terrorist Networks Just Glorified Criminal Cells?, Elie Alhajjar, Ryan Fameli, Shane Warren

Northeast Journal of Complex Systems (NEJCS)

The notions of organized crime and terrorism have an old and rich history around the globe. Researchers and practitioners have been studying events and phenomena related to these notions for a long time. There are pointers in the literature in which it is misleading to see the unfair comparison between terrorist and criminal networks with the argument that all actors involved in these networks are simply evil individuals. In this paper, we conduct a systematic study of the operational structure of such networks from a network science perspective. We highlight some of the major differences between them and support our …

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Recent Advances In Terahertz Photonic Technologies Based On Graphene And Their Applications, Tianjing Guo, Christos Argyropoulos Mar 2021

Recent Advances In Terahertz Photonic Technologies Based On Graphene And Their Applications, Tianjing Guo, Christos Argyropoulos

Department of Electrical and Computer Engineering: Faculty Publications

Graphene is a unique 2D material that has been extensively investigated due to its extraordinary photonic, electronic, thermal, and mechanical properties. Excited plasmons along its surface and other unique features are expected to play an important role in many emerging photonic technologies with drastically improved and tunable functionalities. This review is focused on presenting several recently introduced photonic phenomena based on graphene, beyond its usual linear response, such as nonlinear, active, topological, and nonreciprocal effects. The physical mechanisms and various envisioned photonic applications corresponding to these novel intriguing functionalities are also reported. The presented graphene-based technologies promise to revolutionize the …

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Impact Of Critical Material Attributes (Cmas)-Particle Shape On Miniature Pharmaceutical Unit Operations., Mohammad A Azad, Gerard Capellades, Allison B Wang, David M Klee, Gregory Hammersmith, Kersten Rapp, David Brancazio, Allan S Myerson Mar 2021

Impact Of Critical Material Attributes (Cmas)-Particle Shape On Miniature Pharmaceutical Unit Operations., Mohammad A Azad, Gerard Capellades, Allison B Wang, David M Klee, Gregory Hammersmith, Kersten Rapp, David Brancazio, Allan S Myerson

Henry M. Rowan College of Engineering Departmental Research

The U.S. Food and Drug Administration (FDA) emphasizes drug product development by Quality by Design (QbD). Critical material attributes (CMAs) are a QbD element that has an impact on pharmaceutical operations and product quality. Pharmaceutical drugs often crystallize as needle-shaped (a CMA) particles and affect the process due to poor flowability, low bulk density, and high compressibility, and eventually the product performance. In this study, the product obtained from crystallization was needle-shaped Ciprofloxacin HCl (CIPRO), formed lumps during drying, and compacted during processing through feeders. To delump small amounts of materials and break the needles, multiple available devices (mortar-pestle, Krups …

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Can Subjective Pain Be Inferred From Objective Physiological Data? Evidence From Patients With Sickle Cell Disease, Mark J. Panaggio, Daniel M. Abrams, Fan Yang, Tanvi Banerjee, Nirmish R. Shah Mar 2021

Can Subjective Pain Be Inferred From Objective Physiological Data? Evidence From Patients With Sickle Cell Disease, Mark J. Panaggio, Daniel M. Abrams, Fan Yang, Tanvi Banerjee, Nirmish R. Shah

Computer Science and Engineering Faculty Publications

Patients with sickle cell disease (SCD) experience lifelong struggles with both chronic and acute pain, often requiring medical interventMaion. Pain can be managed with medications, but dosages must balance the goal of pain mitigation against the risks of tolerance, addiction and other adverse effects. Setting appropriate dosages requires knowledge of a patient's subjective pain, but collecting pain reports from patients can be difficult for clinicians and disruptive for patients, and is only possible when patients are awake and communicative. Here we investigate methods for estimating SCD patients' pain levels indirectly using vital signs that are routinely collected and documented in …

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Abiotic Sensor For Electrochemical Determination Of Chlorpyrifos In Natural Water Based On The Inhibition Of Silver Nanoparticles Oxidation, Ziad Khalifa, Moustafa Zahran, Magdy Zahran, Magdi Abdelazzem Mar 2021

Abiotic Sensor For Electrochemical Determination Of Chlorpyrifos In Natural Water Based On The Inhibition Of Silver Nanoparticles Oxidation, Ziad Khalifa, Moustafa Zahran, Magdy Zahran, Magdi Abdelazzem

Chemical Engineering

Chlorpyrifos, organophosphorus pesticide, is a persistent organic pollutant that may cause serious health problems. Herein, a simple, green, and sensitive electrochemical inhibition sensor based on silver nanoparticles (AgNP)-modified glassy carbon (GC) electrode was developed for the determination of chlorpyrifos in natural water for the first time. The chemical reduction technique based on natural reducing and capping agents such as dissolved organic matter (DOM), natural latex (NL) and mucilage was employed for AgNP synthesis. DOM-AgNP, NL-AgNP, and Mucilage-AgNP were immobilized on GC by sticking technique under the same voltammetric and electrolytic conditions. The oxidation behavior of the three modified electrodes was …

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The Age-Dependent Characterization Of The Er-Alpha Positive Breast Cancer Tumor Microenvironment, Katie Marie Hamel Mar 2021

The Age-Dependent Characterization Of The Er-Alpha Positive Breast Cancer Tumor Microenvironment, Katie Marie Hamel

LSU Doctoral Dissertations

In disease states such as cancer, endocrine and paracrine signals from adipose tissue contribute to cancer progression and drug resistance. Young individuals diagnosed with estrogen receptor-alpha positive (ER-a+) breast cancer have an observed increase in resistance to endocrine therapies. This suggests that an alternative estrogen signaling pathway is active within these tumors. Despite this, the effects of stromal age on the endocrine response in breast cancer is not well known. Here, we review and highlight the involvement of the stromal age in both tumorigenesis and physiological wound healing. To identify specific differences between young and aged ER-a+ breast tumors, RNA …

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An Analysis Of Suspended Sediment Dynamics In A Partially Mixed Estuary, Riyadh Hamad Muttaleb Mar 2021

An Analysis Of Suspended Sediment Dynamics In A Partially Mixed Estuary, Riyadh Hamad Muttaleb

Dissertations and Theses

The purpose of this work is to investigate via data analysis and numerical modeling the SPM (suspended particulate matter) dynamics of a heavily contaminated partially urban estuary, the Lower Passaic River estuary (LPR), NJ. Accordingly, I investigate the quantity and mechanics of variation of fine and coarse SPM in the LPR via data analysis. Data analysis focuses on the parameters that affect SPM dynamics at six moored stations occupied during the Fall and Spring seasons, from near the estuary mouth to tidal freshwater. A 3D hydrodynamic model (Delft3D-FM) is used to analyze the effects of estuary topography on the dynamic …

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On The Impact Of Gravity Compensation On Reinforcement Learning In Goal-Reaching Tasks For Robotic Manipulators, Jonathan Fugal, Hasan A. Poonawala, Jihye Bae Mar 2021

On The Impact Of Gravity Compensation On Reinforcement Learning In Goal-Reaching Tasks For Robotic Manipulators, Jonathan Fugal, Hasan A. Poonawala, Jihye Bae

Electrical and Computer Engineering Faculty Publications

Advances in machine learning technologies in recent years have facilitated developments in autonomous robotic systems. Designing these autonomous systems typically requires manually specified models of the robotic system and world when using classical control-based strategies, or time consuming and computationally expensive data-driven training when using learning-based strategies. Combination of classical control and learning-based strategies may mitigate both requirements. However, the performance of the combined control system is not obvious given that there are two separate controllers. This paper focuses on one such combination, which uses gravity-compensation together with reinforcement learning (RL). We present a study of the effects of gravity …

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Plasmonic Photocatalysis For Gas-Phase Degradation Of Total Volatile Organic Compounds: Theory, Experimentation, And Catalyst Stability, Amaury P. Betancourt Iii Mar 2021

Plasmonic Photocatalysis For Gas-Phase Degradation Of Total Volatile Organic Compounds: Theory, Experimentation, And Catalyst Stability, Amaury P. Betancourt Iii

USF Tampa Graduate Theses and Dissertations

Plasmonic nanomaterials have become a strong contender for improving the efficiency of photocatalytic degradation of air pollutants. This study demonstrates an easy and scalable fabrication method, employing electron beam evaporation and rapid thermal annealing, for producing plasmonic photocatalysts. Samples were made by either coating silver on, or layering silica-protected (i.e., silica-coated) or unprotected (i.e., uncoated) silver beneath, the photocatalyst (either zinc oxide or titanium dioxide). Stability and catalytic performance for gas-phase toluene degradation was assessed by monitoring total volatile organic compound (TVOC) concentration versus ultraviolet-A (UV-A) illumination time in a recirculating batch reactor (plate-type flow-through). Samples were characterized using a …

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