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Full-Text Articles in Entire DC Network
Ankimedbench: Evaluating Hierarchical Medical Knowledge In Language Model Embeddings, Neel Patel
Ankimedbench: Evaluating Hierarchical Medical Knowledge In Language Model Embeddings, Neel Patel
UNLV Theses, Dissertations, Professional Papers, and Capstones
Despite achieving over 90% accuracy on medical benchmarks, recent studies show physicians cannot effectively leverage language models to improve clinical reasoning. Current benchmarks test isolated factual recall, but clinical practice requires hierarchical navigation through diagnostic categories—starting broad and narrowing systematically from chest pain to cardiovascular pathology to myocardial infarction to specific STEMI types. Existing evaluations cannot measure whether models preserve this taxonomic structure essential for clinical reasoning.
We introduce AnkiMedBench, built from 16,512 medical flashcards used by students preparing for licensing exams. Cards are organized across six hierarchy levels spanning 16 broad medical specialties to 672 specific diseases and conditions. …
Investigating The Fatigue Behavior Of Inconel 939 And Inconel 718 Through Micromechanical Testing, Mohammad Hossein Shahini
Investigating The Fatigue Behavior Of Inconel 939 And Inconel 718 Through Micromechanical Testing, Mohammad Hossein Shahini
LSU Doctoral Dissertations
A detailed evaluation of fatigue crack growth (FCG) in a silicon-modified Inconel 939 alloy, fabricated via laser powder bed fusion additive manufacturing (L-PBF AM), was performed using cyclic bending tests on pre-notched microscale cantilevers with a cross-sectional dimension of 25 µm × 25 µm. To our knowledge, this study is the first to demonstrate that such microscale cantilever tests can effectively capture both the threshold and Paris-law regimes of FCG, despite the limited specimen size. The precise fabrication of these small-scale specimens allows for controlled fatigue crack propagation relative to the microstructure while minimizing the presence of volumetric defects. Notably, …
Design And Evaluation Of The Influence Of Mutual Induction On Microbial Electrolysis Cell Performance And Biogas Production, Ashley L. Blackwell
Design And Evaluation Of The Influence Of Mutual Induction On Microbial Electrolysis Cell Performance And Biogas Production, Ashley L. Blackwell
Civil Engineering ETDs
Microbial electrolysis cells (MECs) present a pathway for energy recovery in wastewater treatment by converting organic substrates into methane or hydrogen. Traditional MEC designs typically rely on physical electrode contacts and expensive materials, which restrict their scalability. This study introduces the first induction-based MEC that uses mutual inductance between an external copper wrap and an internal coil to generate a fluctuating electrical potential, removing the need for expensive electrodes. The induction-stimulated reactor showed faster total organic carbon removal and a higher CH4/CO2 ratio compared to a conventional anaerobic digester, indicating improved carbon-to-methane conversion, although total gas yield remained similar. Microbial …
Thermally Stable And Regenerable Catalysts For Alkane Dehydrogenation, Ryan Alcala
Thermally Stable And Regenerable Catalysts For Alkane Dehydrogenation, Ryan Alcala
Chemical and Biological Engineering ETDs
Shale gas upgrading reactions have gained much interest since production dramatically increased around 2010. These reactions occur at high temperatures (600°C +) where undesired processes like sintering and/or coking often occur. It is of interest to use materials like ceria as a catalyst support in these alkane conversion reactions, but ceria is prone to losing active surface area through sintering. It is also of interest to understand the behavior of PtMn and PtZn intermetallics for propane dehydrogenation as they have been identified as some of the best catalysts by theory-based prediction in literature. This manuscript explores ways of utilizing ceria’s …
Application Of Bimetallic Transition Metal Oxides Electrocatalysts For Li-Co2 Batteries And Li-O2 Batteries, Jianda Wang
Application Of Bimetallic Transition Metal Oxides Electrocatalysts For Li-Co2 Batteries And Li-O2 Batteries, Jianda Wang
Chemical and Biological Engineering ETDs
Li-ion batteries are the dominant commercial rechargeable batteries nowadays, which are used in electronic devices and electrified transportation widely. However, undesirable energy density of Li-ion batteries prohibits them from meeting requirements of new generation electronic devices. Therefore, it is important to find more alternative electronic energy storage systems with higher capacity. Fortunately, Li-CO2 batteries, featured high capacity and ability to convert CO2, have become a promising candidate to replace Li-ion batteries. In addition, Li-O2 batteries also attract people’s attention due to their high energy density and low cost. However, Li-CO2 batteries and Li-O2 batteries both face challenges of terrible cycle …
Recreating Fiber Recruitment With Fiber Recruitment Using Additive Manufacturing, Natalia D. Mciver
Recreating Fiber Recruitment With Fiber Recruitment Using Additive Manufacturing, Natalia D. Mciver
Biomedical Engineering ETDs
Injured ligaments are often repaired with tendon grafts which may over or under constrain the joint; there is a need for an artificial graft option with the mechanical properties of a native ligament. Crimped fibers within ligaments allow for recruitment which means the viscoelastic properties of stress relaxation and creep are not inversely related. A feasibility study using ACLs and large-scale crimp models to study viscoelasticity, led to an in-depth analysis of the scapholunate interosseous ligament. Using the Modified Kelvin spring-dashpot model, for describing viscoelasticity with a variable stiffness property (time dependent fiber recruitment), we defined the relationship between creep …
Irregularities In The Dynamics Of Large Networks: Cases On Social Networks And The Internet, Dheeman Saha, Abdullah Mueen, Shuang Luan, Afsah Anwar, Yangsun Hong
Irregularities In The Dynamics Of Large Networks: Cases On Social Networks And The Internet, Dheeman Saha, Abdullah Mueen, Shuang Luan, Afsah Anwar, Yangsun Hong
Computer Science ETDs
Dynamic networks capture evolving relationships among entities, and irregularities in their behavior often signal significant events. This dissertation investigates such irregularities across social and infrastructural networks. First, we analyze Twitter (prior to its rebranding to X) to characterize influencers, introducing a follower-overlap similarity measure that identifies micro-influencers beyond content-based methods.
We then examine election-related irregularities by comparing suspended and non-suspended accounts during the 2020 U.S. presidential election, revealing behavioral patterns linked to misinformation and coordinated manipulation.
Next, we develop an algorithm to infer post-specific diffusion networks, reconstructing who-saw-from-whom pathways for tweets at scale. This method uncovers structural differences in diffusion …
“Bridging The Gap To Midwave Infrared Event-Based Sensors: Design, Sensitivity, And Radiation-Hardness Characterization Of A Single-Pixel Iii-V Event-Based Infrared Sensor For Space Applications, Zinah M. Alsaad
Electrical and Computer Engineering ETDs
Event-based sensing presents a revolutionary paradigm shift for next-generation space surveillance systems, where power consumption is an ever-worsening constraint as temporal resolution demands increase. In addition to reduced power consumption, low latency, and wide dynamic range, the event-based sensor fundamentally only produces data when there is a change in illumination from which events are generated; no data is produced if the scene remains static. With their event-based datastream being inherently focused on the dynamic information of the scene, they are particularly well-suited to machine vision and autonomous sensing applications. While these sensors have many compelling advantages, there are presently no …
Metamaterial-Based Microstrip Antenna For Safe Detection Of Tiny Breast Tumors, Shrouk E. El-Sawy, Mohamed G. Abdelfattah, Nihal F.F. Areed, Ahmed Shaban Samra
Metamaterial-Based Microstrip Antenna For Safe Detection Of Tiny Breast Tumors, Shrouk E. El-Sawy, Mohamed G. Abdelfattah, Nihal F.F. Areed, Ahmed Shaban Samra
Mansoura Engineering Journal
This study describes the construction of a compact microstrip patch antenna (MPA) with a triangular-shaped metamaterial layer for the safe detection of tiny breast tumors at 2.4 GHz. The metamaterial considerably improves the antenna's gain and directivity when compared to typical designs that do not include it, resulting in improved detection performance. The radiating patch of proposed antenna measures 29.3 × 38 × 1.6 mm and has been tested through simulations and experimental tests, exhibiting successful tumor identification in a realistic breast phantom. The results of both calculations and testing demonstrate a sensitivity of 6.643 dB/mm, allowing for precise detection …
A Geological And Geochemical Study Of The Philipsburg Mining District, Granite County, Montana, Celine M. Beaucamp
A Geological And Geochemical Study Of The Philipsburg Mining District, Granite County, Montana, Celine M. Beaucamp
Graduate Theses & Non-Theses
The Philipsburg district, renowned for its rich mining history, has contributed significantly to Montana's mineral production, ranking as the state's second-most productive district. Active from 1865 to the 1980s, it yielded an impressive array of Ag (50-60 million oz), with notable outputs of Au, Zn, Pb, Cu, and battery-grade MnO2. The district features Cordilleran polymetallic veins, some of which are along bedding in Mississippian and Devonian limestone, and others are steeply dipping quartz veins in silicate-rich sedimentary rocks and in the Philipsburg batholith. The veins exhibit a district-wide mineral zonation, marked by Cu- and Ag-rich ores near granite porphyries, with …
Aqueous Geochemistry Drives Microbial Cu, Fe, And Zn Uptake Rates In Yellowstone, A Continental Hydrothermal System, Eva Carolina Andrade-Barahona
Aqueous Geochemistry Drives Microbial Cu, Fe, And Zn Uptake Rates In Yellowstone, A Continental Hydrothermal System, Eva Carolina Andrade-Barahona
Graduate Theses & Non-Theses
Microbial uptake of trace metal cofactors such as copper (Cu), iron (Fe), and zinc (Zn) is governed by biogeochemical processes in hydrothermal systems where metal bioavailability varies widely. In situ microbial metal uptake rates were quantified by applying metal stable isotope probing (MSIP) in the Yellowstone hydrothermal system across diverse geochemical conditions in hydrothermal springs. The findings in these studies revealed that pH exerts a dominant influence on microbial copper uptake rate, also enhanced by increased Cu²⁺ ion availability and dissolved oxygen. Microbial iron uptake, in contrast, displayed a broad tolerance to environmental variability, occurring across a pH range of …
Drinking Water Treatment Using Microbial Cellulose Membranes, Benjamin Schreiber
Drinking Water Treatment Using Microbial Cellulose Membranes, Benjamin Schreiber
Graduate Theses & Non-Theses
Access to clean drinking water is a global concern. Existing water filtration technologies require high energy and chemical inputs. They generate a large volume of waste and are not always readily available. This limitation has given rise to the development of sustainable water filtration technologies. This study focused on developing a biodegradable Microbial Cellulose Membrane (MCM) made of bacterial cellulose that is capable of treating a wide variety of pollutants present in environmental water sources. To improve MCM properties for high flux and contaminants removal, they were pre-treated with NaOH (0.25 M). The effect of transmembrane pressure and membrane thickness …
Process Intensification For Rare Earth Elements Adsorption By Resonant Vibratory Mixing (Rvm), Mehran Saddat
Process Intensification For Rare Earth Elements Adsorption By Resonant Vibratory Mixing (Rvm), Mehran Saddat
Graduate Theses & Non-Theses
Rare earth elements (REE) are crucial to the advancement of modern technologies. REE applications include electronics, defense systems, wind turbines, catalysts, magnets, and aircraft. Bastnasite, monazite, and xenotime are the primary resources, while the secondary resources, including coal ash, E-waste, and acid mine drainage, are for REE extraction. The primary processing techniques are chemical leaching, ion exchange, chemical precipitation, pyrometallurgy, solvent exchange, biosorption, and adsorption. Adsorption technique is simple, cost-effective, and environmentally friendly, with higher efficiency but at the cost of a longer mixing time. Therefore, there is a pressing need for an optimized mixing technique to improve the adsorption …
Electrochemical Detection Of No And Ca2+ During Cold Atmospheric Plasma Treatment Of Acute Wounds: Sensor Selectivity And Stability In The Plasma-Bio-System, Jonathan E. Thomas, Kristina Pattison, Suneel Kumar, Gagana Karkada, Duncan Trosan, Aunic Goodin, Jason Rainone, Dnyaneshwari Rananavare, Vandana Miller, Francois Berthiaume, Katharina Stapelmann
Electrochemical Detection Of No And Ca2+ During Cold Atmospheric Plasma Treatment Of Acute Wounds: Sensor Selectivity And Stability In The Plasma-Bio-System, Jonathan E. Thomas, Kristina Pattison, Suneel Kumar, Gagana Karkada, Duncan Trosan, Aunic Goodin, Jason Rainone, Dnyaneshwari Rananavare, Vandana Miller, Francois Berthiaume, Katharina Stapelmann
Kimmel Cancer Center Faculty Papers
Cold atmospheric plasmas (CAP) are a versatile tool in medical applications like wound healing. Its therapeutic benefits are partially attributed to the generation of biologically active reactive oxygen and nitrogen species (RONS). Characterization of RONS, however, typically only occurs after treatment. Here we report the first real-time in situ detection of CAP-generated nitric oxide (NO), and the simultaneous detection of cellular calcium ions (Ca²⁺) release using electrochemical sensors during CAP treatment of murine wounds. In vivo, NO rose rapidly within the first minute of CAP treatment but accumulated less overall than in PBS, reflecting reactions with wound-bed targets. In situ …
The Effects Of Nanobubble Fertigation And Soil Conditioners To Improve Nutrient Dynamics, Soil Microbial Activity, And Chili Productivity, Betty Natalie Fitriatin, Euis Ahah Rokayah, Elsa Naila Elmyra, Tualar Simarmata, Nicky Oktav Fauziah, Hanif Fakhrurroja
The Effects Of Nanobubble Fertigation And Soil Conditioners To Improve Nutrient Dynamics, Soil Microbial Activity, And Chili Productivity, Betty Natalie Fitriatin, Euis Ahah Rokayah, Elsa Naila Elmyra, Tualar Simarmata, Nicky Oktav Fauziah, Hanif Fakhrurroja
Jurnal Kultivasi
Drip fertigation is a fertilization method that integrates nutrient delivery with an irrigation system, which is capable of optimizing the direct delivery of nutrients to the root zone. This experiment aims to investigate the effect of drip fertigation with nanobubble technology, and soil conditioners on the population of Phosphate-Solubilizing Bacteria (PSB) and Azotobacter spp., available phosphorus, total nitrogen, growth, and yield of red chili. The study used a Strip Plot Design with two factors and three replications. The first factor was nutrient application (solid NPK fertilizing as control; drip fertigation; and drip fertigation with nanobubble technology), and the second factor …
Use Of Mid-Infrared Spectroscopy For Estimating Soil Chemical, Physical, And Hydrological Properties In Mississippi And Texas, Kanthake Yasas Bandara Gamagedara
Use Of Mid-Infrared Spectroscopy For Estimating Soil Chemical, Physical, And Hydrological Properties In Mississippi And Texas, Kanthake Yasas Bandara Gamagedara
Theses and Dissertations
Accurate and efficient estimation of soil properties is essential for advancing sustainable agriculture, water management, and soil survey applications. Traditional laboratory methods and pedotransfer functions (PTFs) are widely used but are often constrained by high costs, time requirements, and limited scalability. As an alternative, mid-infrared (MIR) and visible–near-infrared (vis–NIR) spectroscopy provide cost-effective, rapid, and non-destructive approaches for soil analysis. However, variability among spectrometer types, geographic regions, and soil scanning conditions poses challenges to model transferability and generalizability. This dissertation evaluated strategies to overcome these challenges and enhance the prediction of soil chemical, physical, and hydrological properties in Mississippi and Texas. …
Leveraging Google Earth Engine For Computationally Efficient Pixel-Level Analysis And Vector Delineation From Satellite Data., Rishita Garg
Leveraging Google Earth Engine For Computationally Efficient Pixel-Level Analysis And Vector Delineation From Satellite Data., Rishita Garg
Theses and Dissertations
Analyzing large-scale, high-resolution satellite imagery is a computationally intensive task requiring time and computing resources. This can be accelerated using cloud computing platforms such as Google Earth Engine (GEE) where computational and storage requirements can be scaled based on demand. However, cloud-based platforms for processing high-resolution imagery remain underutilized in environmental applications such as agriculture, and forest health. This thesis explored the application of GEE to two geospatial problems in agricultural conservation and disease mapping in forestry: 1) Extraction of agricultural field boundaries from Sentinel-2 satellite imagery, for use in conservation, precision agriculture, land management, and organization, etc., and 2) …
Considerations For Cottonseed Oil As A Feedstock For Renewable Fuels, John Elmore
Considerations For Cottonseed Oil As A Feedstock For Renewable Fuels, John Elmore
Theses and Dissertations
As the world population grows and the standard of living improves in developing countries, global energy demand will continue to rise, with energy use in the developing world expected to increase dramatically more than the per capita reductions in developed countries from efficiency improvements. Nearly a third of the total global energy demand is used for transportation, resulting in a substantial contribution to greenhouse gas (GHG) emissions. While the demand for energy rises, initiatives and regulations are underway to mitigate the amount of GHG emissions to Earth’s atmosphere. As efforts progress in industry, governments, and society to reduce the total …
Electrospun Nanofiber Creation With Varying Polymer-Solvent Combinations For Air Filtration, Lancaster Jace Hill
Electrospun Nanofiber Creation With Varying Polymer-Solvent Combinations For Air Filtration, Lancaster Jace Hill
Theses and Dissertations
This study aims to analyze various polymer-solvent combinations for electrospun creation of nanofiber media and to determine the best-suited solution for lab-grade electrospinning. Suitable solutions allow for controlled morphology of fiber diameters and for efficiency of media creation. The principal variables are solvent, concentration, and voltage. Humidity and temperature play a secondary variable role. The solution must withstand an electric field of ≤30 kV and be insoluble in water to maintain desired morphology and structure. Manipulation of the solutions and variables allow for fiber diameter optimization and beading minimization. High temperature filter applications require efficiency in intense heat and preservation …
Lecun-Pso Hybrid Initialization Of Neural Network Using Asymmetric Gait Features For Classification Of Parkinson’S Disease, Michael Joseph Carter
Lecun-Pso Hybrid Initialization Of Neural Network Using Asymmetric Gait Features For Classification Of Parkinson’S Disease, Michael Joseph Carter
Theses and Dissertations
Parkinson's disease (PD) is a complex condition with a wide range of clinical symptoms. It is a progressive neurological disorder that has afflicted an estimated 1 million people in the US and 10 million worldwide. The diagnosis of PD is typically based on the presence of clinical features, with no specific diagnostic test or biomarker. The methods of assessment for PD are also used, in whole or in part, for similar symptom diseases such as Multiple Sclerosis, Essential Tremors, Multiple System Atrophy, Supranuclear Palsy, Dementia with Lewy bodies and Huntington’s disease. Many of the current clinical tests have low sensitivity …
Design And Development Of Rechargeable Cement-Based Batteries For Energy Storage Within Infrastructure, Dandan Yin
Design And Development Of Rechargeable Cement-Based Batteries For Energy Storage Within Infrastructure, Dandan Yin
Tennessee State University Alumni Theses and Dissertations
This dissertation presented the design, fabrication, and evaluation of rechargeable cement-based batteries (CBB) for energy storage within infrastructure. The study aimed to integrate electrochemical energy storage directly into cementitious materials, enabling multifunctional and sustainable building systems. Nickel–iron electrodes and cement-based solid electrolytes to form durable, solid-state systems. The electrochemical impedance spectroscopy, cyclic voltammetry, and galvanostatic charge–discharge tests,along with microscopic testing and mechanical testing analyses, were conducted to assess battery performance. The carbon fiber mesh CBB achieved stable cycling over 100 cycles with quasi-reversible redox behavior and a maximum areal energy density of 7.6 Wh m⁻². Nickel foam electrodes, with their …
Mechanical Quality Of Hemp Fiber As Influenced By Tillage, Cover Crop, And Nitrogen Management In Regenerative Organic Systems, Parinaz Heydar, Alyssa Pierce, Gabriella Fioravanti, Ronald Kander
Mechanical Quality Of Hemp Fiber As Influenced By Tillage, Cover Crop, And Nitrogen Management In Regenerative Organic Systems, Parinaz Heydar, Alyssa Pierce, Gabriella Fioravanti, Ronald Kander
School of Design and Engineering Papers
Industrial hemp (Cannabis sativa L.) is an emerging crop for renewable fiber materials. For farmers, finding a balance between agronomic performance and economic return is crucial, especially when targeting specific markets like the textile industry, which values not just fiber quantity, but overall quality. This field study, conducted at the Rodale Institute in Kutztown, Pennsylvania, assessed the effects of tillage (till vs. no till), cover crop (with cover vs. no cover), and nitrogen (N) rate (0, 50, 100, 150 kg ha⁻¹) on hemp fiber yield, N concentrations in leaf and stalk, and mechanical performance under regenerative organic conditions. Fiber mechanical …
Evaluation Of Internal Field In Ppln And Studies On Qpm Shg Efficiency Factor, Prasath Rk Mr
Evaluation Of Internal Field In Ppln And Studies On Qpm Shg Efficiency Factor, Prasath Rk Mr
Theses and Dissertations
Periodically Poled Lithium Niobate (PPLN) crystals have attracted interest in optoelectronics and nonlinear optics. The response to the applied electric field is determined by their larger electro-optic and nonlinear optical coefficients. An internal electric field exists in congruent PPLN crystals due to its defects. Its evaluation is important in controlling the electro-optical behavior. A simple nondestructive diffraction method is proposed to estimate the internal electric field present in the congruent lithium niobate crystal.
Due to the presence of an unrelaxed internal field, the as-poled sample acts as an index grating. When a light is incident on such a sample, it …
High-Resolution Lidar Observations Of Sedimentation-Induced Size Sorting Of Droplets Near A Laboratory Cloud Top, Fan Yang, Yong Meng Sua, Zipei Zheng, Jesse Anderson, Hamed F. Sadi, Jae Min Yeom, Suryadev Pratap Singh, Pei Hou, Will Cantrell, Ernie Lewis, Alex Kostinski, Raymond Shaw
High-Resolution Lidar Observations Of Sedimentation-Induced Size Sorting Of Droplets Near A Laboratory Cloud Top, Fan Yang, Yong Meng Sua, Zipei Zheng, Jesse Anderson, Hamed F. Sadi, Jae Min Yeom, Suryadev Pratap Singh, Pei Hou, Will Cantrell, Ernie Lewis, Alex Kostinski, Raymond Shaw
Michigan Tech Publications
No abstract provided.
Multitaskvenationnet: A Multi-Task Deep Neural Network With Strip Pooling And Hybrid Upsampling For Leaf Vein Segmentation, Ishak Ariawan, Ahmad Ashari, Moh. Edi Wibowo
Multitaskvenationnet: A Multi-Task Deep Neural Network With Strip Pooling And Hybrid Upsampling For Leaf Vein Segmentation, Ishak Ariawan, Ahmad Ashari, Moh. Edi Wibowo
Iraqi Journal for Computer Science and Mathematics
Leaf vein segmentation is a critical task in plant phenotyping and species classification, yet it remains challenging due to the hierarchical, curvilinear nature of veins and interference from complex backgrounds. Existing methods face three key limitations. First, they lack directional context modeling, leading to blurred vein boundaries and the omission of fine venation. Second, they fail to effectively capture global dependencies, limiting semantic coherence across spatial regions. Third, they do not incorporate explicit mechanisms for detecting vein discontinuities, which is essential for complete topological understanding. To address these challenges, we propose MultiTaskVenationNet (MTV-Net), a multi-task deep segmentation framework that integrates …
A Review Of Bioactive Compounds Of Caesalpinia Sappan: Pre- And Post-Harvest Effect, Annisa Lugina Rachman, Santi Rosniawaty, Syariful Mubarok, Cucu Suherman, Yudithia Maxiselly
A Review Of Bioactive Compounds Of Caesalpinia Sappan: Pre- And Post-Harvest Effect, Annisa Lugina Rachman, Santi Rosniawaty, Syariful Mubarok, Cucu Suherman, Yudithia Maxiselly
Jurnal Kultivasi
Sappanwood (Caesalpinia sappan L.) is a shrub or small tree that thrives in tropical regions and has been widely distributed across various areas. It has long been used as a natural dye in textiles, cosmetics, and herbal beverages due to its content of various bioactive compounds. This literature review discusses the secondary metabolites in sappanwood, their health benefits, and strategies to enhance product quality through pre-harvest and post-harvest treatments. This literature review was conducted by searching for relevant journals on Google Scholar using relevant keywords. Sappanwood contains diverse secondary metabolites, including flavonoids, phenolics, anthraquinones, triterpenoids, steroids, alkaloids, and tannins, with …
Advancing Radiation Shielding For Human Space Exploration, Bryan Trejo, Lea Scott, Eduardo Farfan
Advancing Radiation Shielding For Human Space Exploration, Bryan Trejo, Lea Scott, Eduardo Farfan
Symposium of Student Scholars
Beyond the safety of the Earth's magnetic field, out into the treacherous reaches of space, lies a harsh environment of radiation. This study examines radiation shielding strategies for crewed spacecraft operating in various environments, including Mars transit and deep space. Within these environments, ionizing radiation remains a critical challenge to long-duration, crewed space travel. Galactic Cosmic Rays (GCR), high-energy protons and heavy nuclei originating outside our solar system, as well as Solar Particle Events (SPE), highly energetic protons ejected continuously during the 11-year solar cycle, are all analyzed in their unique interactions with spacecraft material and biological tissues. Shielding to …
Engineered Multifunctional Drug-Loaded Dendrimer Nanoparticles For Glaucoma: Triple Mechanism Via Antioxidant Activity, Iron Chelation, And Enhanced Ocular Transport, Burhan Ates, Ashish Trital, Vimalin Jeyalatha Mani, Lei Xu, Jonathan Kenlee, Nuran Ercal, Hu Yang
Engineered Multifunctional Drug-Loaded Dendrimer Nanoparticles For Glaucoma: Triple Mechanism Via Antioxidant Activity, Iron Chelation, And Enhanced Ocular Transport, Burhan Ates, Ashish Trital, Vimalin Jeyalatha Mani, Lei Xu, Jonathan Kenlee, Nuran Ercal, Hu Yang
Chemistry Faculty Research & Creative Works
In this study, we developed multifunctional nanoparticles based on polyamidoamine (PAMAM) dendrimers functionalized with caffeic acid (CA) and poly (ethylene glycol) maleimide (PEGM) for the topical delivery of hydrophobic antiglaucoma drugs brimonidine (BM) and betaxolol (BX). The PAMAM-CA and PAMAM-CA-PEGM conjugates exhibited antioxidant and iron-chelating activities in a dose-dependent manner. BM- and BX-loaded dendrimer nanoparticles produced using a multi-inlet vortex mixer showed uniform spherical morphology (∼80 nm by TEM) and hydrated sizes of ∼135-144 nm by DLS. Both nano formulations demonstrated high cytocompatibility with human corneal epithelial cells and were nonirritant in the HET-CAM assay, with PEGM further improving cytocompatibility. …
Mechanistic Modelling And Parameter Estimation Of Heterogeneous Catalytic Synthesis Of Green Fuel, Rasheed U. Owolabi, Obinna P. Anele, Mohammed A. Usman
Mechanistic Modelling And Parameter Estimation Of Heterogeneous Catalytic Synthesis Of Green Fuel, Rasheed U. Owolabi, Obinna P. Anele, Mohammed A. Usman
Mansoura Engineering Journal
Investigation of the kinetics and mechanistic modelling of biodiesel synthesis through the reaction of castor oil with methanol under catalyzed conditions was carried out in this study. The reaction mechanisms of the Eley-Rideal, Langmuir-Hinshelwood-Hougen-Watson, and Hattori type were employed to identify the rate-determining or controlling step of the reaction. Thirteen rate expressions were developed for reactant adsorption, product desorption, and surface chemical reactions. The experimental data from Sanchez-Cantu et al. were used to validate the models, and the best-fitting model and parameter estimation were evaluated using SAS and MATLAB software. From the results, the Eley-Rideal mechanism with glycerol desorption as …
Space Agriculture: A Comprehensive Systems-Level Review Of Challenges And Opportunities, Hassan Fazayeli, Aaron Lee M. Daigh, Cassandra Palmer, Santosh Pitla, David Jones, Yufeng Ge
Space Agriculture: A Comprehensive Systems-Level Review Of Challenges And Opportunities, Hassan Fazayeli, Aaron Lee M. Daigh, Cassandra Palmer, Santosh Pitla, David Jones, Yufeng Ge
Biological Engineering Faculty Publications
As humanity prepares for prolonged space missions and future extraterrestrial settlements, developing reliable and resilient food-production systems is becoming a critical priority. Space agriculture, the cultivation of plants beyond Earth (particularly on the Moon and Mars), faces a constellation of interdependent environmental, biological, and engineering challenges. These include limited solar radiation, elevated ionizing radiation, large thermal variability, non-Earth atmospheric pressures, reduced gravity, regolith substrates with low nutrient-holding capacity, high-CO2/low-O2 atmospheres, pervasive dust, constrained water and nutrient availability, altered plant physiology, and the overarching need for closed-loop, resource-efficient systems. These stressors create an exceptionally challenging environment for plant …