Digital Commons Network^™

Analysis And Characterization Of Microplastics In Water Treatment Plants

Symposium of Student Scholars

Plastic pollution is a growing public concern due to its effect on our environment and oceans. Based on the increasing prevalence of microplastics in the environment, they are now present in potable water. Microplastics can be defined as pieces of synthetic polymers that can typically be measured to be smaller than five millimeters. Microplastics can stem from sources such as beauty products containing microbeads, polystyrene foam packaging, and the deterioration of disposable plastic items. Much of this waste enters natural water bodies, which is the source of our drinking water. Little is known about the microplastics contaminating our water treatment …

Security And Privacy Analysis Of Wearable Health Device, Abm Kamrul Islam Riad

Symposium of Student Scholars

Wearable technology allows for consumers to record their healthcare data for either personal or clinical use via portable devices. As advancements in this technology continue to rise, the use of these devices has become more widespread. In this paper, we examine the significant security and privacy features of three health tracker devices: Fitbit, Jawbone and Google Glass. We also analyze the devices' strength and how the devices communicate via its Bluetooth pairing process with mobile devices. We explore possible malicious attacks through Bluetooth networking. The outcomes of this analysis illustrate how these devices allow third parties to access sensitive information, …

Colloidal Quantum Dot (Cqd) Based Mid-Wavelength Infrared Optoelectronics, Shihab Bin Hafiz

Dissertations

Colloidal quantum dot (CQD) photodetectors are a rapidly emerging technology with a potential to significantly impact today’s infrared sensing and imaging technologies. To date, CQD photodetector research is primarily focused on lead-chalcogenide semiconductor CQDs which have spectral response fundamentally limited by the bulk bandgap of the constituent material, confining their applications to near-infrared (NIR, 0.7-1.0 um) and short-wavelength infrared (SWIR, 1-2.5 um) spectral regions. The overall goal of this dissertation is to investigate a new generation of CQD materials and devices that advances the current CQD photodetector research toward the technologically important thermal infrared region of 3-5 ?m, known as …

Gradient Free Sign Activation Zero One Loss Neural Networks For Adversarially Robust Classification, Yunzhe Xue

Dissertations

The zero-one loss function is less sensitive to outliers than convex surrogate losses such as hinge and cross-entropy. However, as a non-convex function, it has a large number of local minima, andits undifferentiable attribute makes it impossible to use backpropagation, a method widely used in training current state-of-the-art neural networks. When zero-one loss is applied to deep neural networks, the entire training process becomes challenging. On the other hand, a massive non-unique solution probably also brings different decision boundaries when optimizing zero-one loss, making it possible to fight against transferable adversarial examples, which is a common weakness in deep learning …

Multi-Stage Stochastic Optimization And Reinforcement Learning For Forestry Epidemic And Covid-19 Control Planning, Sabah Bushaj

Dissertations

This dissertation focuses on developing new modeling and solution approaches based on multi-stage stochastic programming and reinforcement learning for tackling biological invasions in forests and human populations. Emerald Ash Borer (EAB) is the nemesis of ash trees. This research introduces a multi-stage stochastic mixed-integer programming model to assist forest agencies in managing emerald ash borer insects throughout the U.S. and maximize the public benets of preserving healthy ash trees. This work is then extended to present the first risk-averse multi-stage stochastic mixed-integer program in the invasive species management literature to account for extreme events. Significant computational achievements are obtained using …

Towards Adversarial Robustness With 01 Lossmodels, And Novel Convolutional Neural Netsystems For Ultrasound Images, Meiyan Xie

Dissertations

This dissertation investigates adversarial robustness with 01 loss models and a novel convolutional neural net systems for vascular ultrasound images.

In the first part, the dissertation presents stochastic coordinate descent for 01 loss and its sensitivity to adversarial attacks. The study here suggests that 01 loss may be more resilient to adversarial attacks than the hinge loss and further work is required.

In the second part, this dissertation proposes sign activation network with a novel gradient-free stochastic coordinate descent algorithm and its ensembling model. The study here finds that the ensembling model gives a high minimum distortion (as measured by …

Towards Understanding The Role Of Central Processing In Release From Masking, Nima Alamatsaz

Dissertations

People with normal hearing have the ability to listen to a desired target sound while filtering out unwanted sounds in the background. However, most patients with hearing impairment struggle in noisy environments, a perceptual deficit which current hearing aids and cochlear implants cannot resolve. Even though peripheral dysfunction of the ears undoubtedly contribute to this deficit, surmounting evidence has implicated central processing in the inability to detect sounds in background noise. Therefore, it is essential to better understand the underlying neural mechanisms by which target sounds are dissociated from competing maskers. This research focuses on two phenomena that help suppress …

Clustering Of Pain Dynamics In Sickle Cell Disease From Sparse, Uneven Samples, Gary K. Nave Jr, Swati Padhee, Amanuel Alambo, Tanvi Banerjee, Nirmish Shah, Daniel M. Abrams

Computer Science and Engineering Faculty Publications

Irregularly sampled time series data are common in a variety of fields. Many typical methods for drawing insight from data fail in this case. Here we attempt to generalize methods for clustering trajectories to irregularly and sparsely sampled data. We first construct synthetic data sets, then propose and assess four methods of data alignment to allow for application of spectral clustering. We also repeat the same process for real data drawn from medical records of patients with sickle cell disease -- patients whose subjective experiences of pain were tracked for several months via a mobile app. We find that different …

An Integrated Model Of Optofluidic Biosensor Function And Performance, Joel Greig Wright, Jr.

Theses and Dissertations

Optofluidic flow-through biosensor devices have been in development for fast bio-target detection. Utilizing the fabrication processes developed by the microelectronics industry, these biosensors can be fabricated into lab-on-a-chip devices with a degree of platform portability. This biosensor technology can be used to detect a variety of targets, and is particularly useful for the detection single molecules and nucleic acid strands. Microfabrication also offers the possibility of production at scale, and this will offer a fast detection method for a range of applications with promising economic viability. The development of this technology has advanced to now warrant a descriptive model that …

Temporal Evolution Of Structure And Function In The Periphery And Central Auditory Systems With Mild Blast Induced Tinnitus In Rat Animal Models, Ningning Shao

Dissertations

Exposure to blast causes debilitating trauma including tinnitus among soldiers and civilians (Cave et al., 2007; Remenschneider et al., 2014; Singh et al., 2016). Tinnitus is a constant ringing noise perception without external acoustic event; it affects sleep, concentration, behavior, leading to suicidal tendencies (Swan et al., 2017). Though blast induced tinnitus has been studied, structural and functional dysfunctions along auditory systems have not been systematically studied. It was hypothesized in this work that blast causes tinnitus even while the ears are mechanically protected, and the damage occurred in both central and peripheral auditory systems, which contributed to increased anxiety …

Drug Releasing Hydrogels For Opioid Use Disorder, Kaytlyn M. Crowe

Theses

Ease of access to prescription opioids and the strength of synthetic opioids have contributed to the rise in over use disorders, overdose, and death rates during the opioid epidemic. The current overdose standard of care, rescue NLX (NLX), is a competitive antagonist to the μ-opioid receptor but has a relatively short period of action compared to opioid agonists, especially synthetic agonists. Rises in the abuse of these synthetic and semi-synthetic agents in recent years have shown the weaknesses of rescue NLX, as it can leave overdose patients vulnerable to renarcotization and precipitated withdrawal. To prevent both from occurring, we developed …

Unintended Consequences Of Air Cleaning Chemistry, Douglas B. Collins, Delphine K. Farmer

Faculty Journal Articles

Amplified interest in maintaining clean indoor air associated with the airborne transmission risks of SARS-CoV-2 have led to an expansion in the market for commercially available air cleaning systems. While the optimal way to mitigate indoor air pollutants or contaminants is to control (remove) the source, air cleaners are a tool for use when absolute source control is not possible. Interventions for indoor air quality management include physical removal of pollutants through ventilation or collection on filters and sorbent materials, along with chemically reactive processes that transform pollutants or seek to deactivate biological entities. This perspective intends to highlight the …

Development And Characterization Of Composite Membranes For Use In Countercurrent Solvent Extraction, Lydia Neves Rodrigues

Dissertations

Porous membranes having a particular wetting characteristic, hydrophobic or hydrophilic, are used for nondispersive membrane solvent extraction (MSX) where two immiscible phases flow on two sides of the membrane. The aqueous-organic phase interface across which solvent extraction/back extraction occurs remains immobilized on one surface of the membrane. This process requires the pressure of the phase not present in membrane pores to be either equal to or higher than that of the phase present in membrane pores; the excess phase pressure should not exceed a breakthrough pressure. In countercurrent MSX with significant flow pressure drop in each phase, this often poses …

Bright And Blind Spots Of Water Research In Latin America And The Caribbean, Alyssa J. Devincentis, Hervé Guillon, Romina Díaz Gómez, Noelle K. Patterson, Francine Van Den Brandeler, Srthur Koehl, Pablo Ortiz-Partida, Laura E. Garza-Díaz, Jennifer Gamez-Rodríguez, Erfan Goharian, Samuel Sandoval Solis

Faculty Publications

Water resources management in Latin America and the Caribbean is particularly threatened by climatic, economic, and political pressures. To assess the region's ability to manage water resources, we conducted an unprecedented literature review of over 20 000 multilingual research articles using machine learning and an understanding of the socio-hydrologic landscape. Results reveal that the region's vulnerability to water-related stresses, and drivers such as climate change, is compounded by research blind spots in niche topics (reservoirs and risk assessment) and subregions (Caribbean nations), as well as by its reliance on an individual country (Brazil). A regional bright spot, Brazil, produces well-rounded …

Silk-Cellulose Acetate Biocomposite Materials Regenerated From Ionic Liquid, Ashley Rivera-Galetti, Chrtstopher R. Gough, Farhan Kaleem, Michael Burch, Chris Ratcliffe, Ping Lu, David Salas-De La Cruz, Xiao Hu

College of Science & Mathematics Departmental Research

The novel use of ionic liquid as a solvent for biodegradable and natural organic biomaterials has increasingly sparked interest in the biomedical field. As compared to more volatile traditional solvents that rapidly degrade the protein molecular weight, the capability of polysaccharides and proteins to dissolve seamlessly in ionic liquid and form fine and tunable biomaterials after regeneration is the key interest of this study. Here, a blended system consisting of Bombyx Mori silk fibroin protein and a cellulose derivative, cellulose acetate (CA), in the ionic liquid 1-ethyl-3-methylimidazolium acetate (EMIMAc) was regenerated and underwent characterization to understand the structure and physical …

Stable Thermally-Modulated Nanodroplet Ultrasound Contrast Agents, Anastasiia Vasiukhina, Javad Estraghi, Adib Ahmadzadegan, Craig J. Goergen, Pavlov P. Vlachos, Luis Solorio

School of Mechanical Engineering Faculty Publications

Liquid perfluorocarbon-based nanodroplets are stable enough to be used in extravascular imaging, but provide limited contrast enhancement due to their small size, incompressible core, and small acoustic impedance mismatch with biological fluids. Here we show a novel approach to overcoming this limitation by using a heating–cooling cycle, which we will refer to as thermal modulation (TM), to induce echogenicity of otherwise stable but poorly echogenic nanodroplets without triggering a transient phase shift. We apply thermal modulation to high-boiling point tetradecafluorohexane (TDFH) nanodroplets stabilized with a bovine serum albumin (BSA) shell. BSA-TDFH nanodroplets with an average diameter under 300 nanometers showed …

Preparation Of Meta-Nitrobenzoylhydrazone Ferrocenoylacetone And Synthesis On Its Basis, Zilola Abduraxmonovna Sulaymonova, Bako Bafayevich Umarov Doctor Chemical Science, Professor

Chemical Technology, Control and Management

β-diketone-ferrocenoylacetone was obtained by Claisen condensation. Meta-nitrobenzoylhydrazone of ferrocenoylacetone (H₂L) was synthesized by the interaction of meta-nitrobenzoic acid hydrazide with ferrocenoylacetone. On its basis, complexes with copper(II) and nickel(II) ions were synthesized. The obtained compounds were characterized by the methods of elemental analysis, IR-, ¹H NMR andelectronic spectroscopy. The research results showed that H₂L in solution exists in the form of a tautomeric mixture: hydrazone, α-hydroxyazine, and cyclic 5-hydroxypyrazoline forms. According to the results of IR and ¹H NMR spectra, the complexes were assigned a planar-square structure, and in them the doubly deprotonated …

Application Of Methods Of Intermittent Ventilation Of Industrial Premises Using A Digital Data Transmission System, Yuriy Shipulin, Abdullayev Temur, Jamolidin Usmanov, Shahnoza Ergasheva

Chemical Technology, Control and Management

The article is devoted to topical applied issues, the application of methods of intermittent ventilation of industrial buildings using a digital data transmission system. The requirements for the parameters of the environment are determined, which include: composition, purity, temperature, air humidity, the content of positive and negative ions, the presence of fields of various origins (thermal, optical, biological, gas, and electromagnetic). The authors of the article argue that some of the listed parameters can be supported by ventilation and air conditioning (SCA) systems.

It is shown that when the controlled parameters are limited to a multidimensional area, the SCA control …

No Ordinary Proteins: Adsorption And Molecular Orientation Of Monoclonal Antibodies, Ankit D. Kanthe, Andrew Ilott, Mary Krause, Songyan Zheng, Jinjiang Li, Wei Bu, Mrinal K. Bera, Binhua Lin, Charles Maldarelli, Raymond S. Tu

Publications and Research

The interaction of monoclonal antibodies (mAbs) with air/water interfaces plays a crucial role in their overall stability in solution. We aim to understand this behavior using pendant bubble measurements to track the dynamic tension reduction and x-ray reflectivity to obtain the electron density profiles (EDPs) at the surface. Native immunoglobulin G mAb is a rigid molecule with a flat, “Y” shape, and simulated EDPs are obtained by rotating a homology construct at the surface. Comparing simulations with experimental EDPs, we obtain surface orientation probability maps showing mAbs transition from flat-on Y-shape configurations to side-on or end-on configurations with increasing concentration. …

A Computational Model For Calcium Signaling In Osteocyte Cell Cultures Under Mechanical Stimulation, Courtney Rose Ogando

Theses - ALL

Bone is a highly complex and organized tissue that is composed of an abundance of cells including the osteocyte. While it is known that osteocytes are responsible for the control of the bone remodeling process and the maintenance of calcium (Ca2+) homeostasis using their network of gap junction connections, their complete role is not yet fully understood. It is also known that various bone related diseases as well as cancer demonstrate an alteration of Ca2+ homeostasis during the progression of the disease. Previous researchers have combined computational modeling with experimental studies to gain a better understanding of cell-to-cell Ca2+ signaling …

Trihalomethanes In Water Supply System And Water Distribution Networks, Sornsiri Sriboonnak, Phacharapol Induvesa, Suraphong Wattanachira, Pharkphum Rakruam, Adisak Siyasukh, Chayakorn Pumas, Aunnop Wongrueng, Eakalak Khan

Civil and Environmental Engineering and Construction Faculty Research

The formation of trihalomethanes (THMs) in natural and treated water from water supply systems is an urgent research area due to the carcinogenic risk they pose. Seasonal effects and pH have captured interest as potential factors affecting THM formation in the water supply and distribution systems. We investigated THM occurrence in the water supply chain, including raw and treated water from water treatment plants (coagulation, sedimentation, sand filtration, ClO2-disinfection processes, and distribution pipelines) in the Chiang Mai municipality, particularly the educational institute area. The effects of two seasons, rainy (September–November 2019) and dry (December 2019–February 2020), acted as surrogates for …

The Influence Of Trailing Edge Shape And Kinematics On Bio-Inspired Pitching Panels, Justin Thomas King

Dissertations - ALL

Recently, some engineers have turned to the study of swimming and flying animals to provide insight into the design of vehicles that move through air or water. For certain animals swimming in water, thrust is generated primarily by either a caudal fin or fluke located at the posterior end of the swimmer. It has been argued extensively in the existing research literature that biological propulsors of high aspect ration that also display forked, or lunate, planforms are representative of optimized propulsor geometries with respect to propulsive performance. However, recent experimental and computational work on purely pitching panels has demonstrated that …

Blood–Brain Barrier Breakdown And Astrocyte Reactivity Evident In The Absence Of Behavioral Changes After Repeated Traumatic Brain Injury, Celeste Dunn, Nasya Sturdivant, Sara Venier, Syed Ali, Jeffery Wolchok, Kartik Balachandran

Biomedical Engineering Faculty Publications and Presentations

Repeated traumatic brain injuries (TBIs) cause debilitating effects. Without understanding the acute effects of repeated TBIs, treatment options to halt further degeneration and damage cannot be developed. This study sought to examine the acute effects of blood–brain barrier (BBB) dysfunction, edema, inflammation and behavioral changes after either a single or double TBI using a C57BL/6 mouse model. We examined the effects of one or two TBIs, of either a mild or moderate severity. Double injuries were spaced 7 days apart, and all analysis was performed 24 h post-injury. To examine edema and inflammation, protein levels of glial fibrillary acidic protein …

Molecular Interfaces And Heterogeneous Bubble Nucleation From Heated Surfaces At Nanoscale, Manish Gupta

Dissertations - ALL

Heat transfer from a solid surface to fluid occurs in numerous applications, such as boilers, refrigerators, power electronics, etc., and include various underlying phenomena of thin-film evaporation, boiling, condensation, surface wetting, and droplet evaporation. Several studies show that heat transfer can be enhanced significantly by incorporating micro and nanoscale features onto surfaces. Phase change heat transfer plays an important role in dissipating energy from hot surfaces and distributing it to bulk liquid due to high latent heat of liquids. Boiling, a phase change heat transfer phenomenon, happens when the surface is heated to a temperature above the saturation temperature of …

Design And Development Of 2d Functional Semiconductor Nanocrystals, Andrew Hunter Davis

Dissertations - ALL

Anisotropic nanocrystals (NCs) have become of keen interest in recent years, especially for applications in optoelectronic devices due to their directionally oriented emissions, narrow emission spectra, and suitable morphologies for device integration. Of the desired anisotropic NCs, two-dimensional (2D) NCs are of profound interest, due to their impressive optical and electronic properties as well as their prospective advantages towards applications in layered optoelectronic devices, such as solar cells. However, 2D NCs face many challenges, including limited synthetic derivation, as well as decreased stability and optical response, due to their large surface-to-volume ratio and reactive planar surface increasing surface defect state …

Cfd Analysis Of Subcutaneous Deposition And Dispersion Of Insulin In Adipose Tissue, Ryan C. Lubbers

Masters Theses

Drug delivery is the most important factor of many therapies, but a lack of technology and research have led to a very generalized understanding of drug kinetics. Insulin pump therapy for the treatment of Type 1 Diabetes depends on precise delivery of the hormone into the adipose region between the dermis and underlying muscle. The kinetics of insulin within the adipose tissue environment is not well understood and varies greatly case to case. The use of computation fluid dynamics (CFD) models to study insulin kinetics in relation to influential factors will lead to a better understanding of the characteristics of …

Effects Of Different Combined Pretreatments On Biogenic Methane Production By Anaerobic Digestion Of Lignite, Zhang Huaiwen, Yao Yiqing, Xie Changwen

Coal Geology & Exploration

Effects of different combined pretreatments on biogenic methane production by anaerobic digestion of lignite

Development Characteristics Of Coal Microfracture And Coal Petrology Control Under Cyclic High Voltage Electrical Pulse, Li Hengle, Qin Yong, Zhou Xiaoting, Zhang Yongmin, Chen Yilin

Coal Geology & Exploration

Development characteristics of coal microfracture and coal petrology control under cyclic high voltage electrical pulse

Engineering The Surface Of Fe3o4 Nanoparticles For Catalytic And Magnetic Applications, Natalia Da Silva Moura

LSU Doctoral Dissertations

With the rapid depletion of the U.S. energy resources coupled with population growth, heat management technologies must be improved to sustain our quality of life. Precisely, in catalysis, it is estimated that only ~50% of the energy supplied to the reactor is used for product conversion due to dissipation losses. Among the emerging technologies with a promising reduction in heat losses is induction heating, offering targeted heat delivery with magnetic nanoparticles. Under alternating magnetic fields (AMF), these nanoparticles can absorb the energy from Radio-Frequency (RF) fields and dissipate it as heat on the nanoparticle surface. This in situ heat generation …

Communications, Decision-Making, And Interactions Of A Multi-Agent Autonomous Vehicle System, Daniel Davis Smith

LSU Doctoral Dissertations

Autonomous vehicles are becoming ever more common and offer many attractive benefits to society. They can operate for long periods of time unattended, operate in environments that may be dangerous to humans, perform time consuming or repetitive tasks and all with greater efficiency and lower costs than humans. For these vehicles to be able to do these things, algorithms need to be designed and optimized that allow them to interact with the real-world environment in safe, effective, and efficient ways.

We designed and built a set of three homogeneous water-based autonomous surface vehicles equipped with appropriate sensors and communications ability …