Digital Commons Network^™

Irrigation Systems Management, Dean E. Eisenhauer, Derrel L. Martin, Derek M. Heeren, Glenn J. Hoffman

Open Educational Resources: Textbooks

Like most textbooks, this book grew out of our desire to have written material that matches the educational needs of both the students and the instructor of a college course, in this case a course entitled Irrigation Systems Management. The book is the culmination of course notes which have been in development and use for nearly 30 years.

The emphasis of this book is on the management of irrigation systems that are used for agricultural crop production. There are two distinct components of the book, starting with the soil-water-plant-atmosphere system and how soil water should be managed to achieve the …

Quantitative Characterization Of Complex Systems—An Information Theoretic Approach, Aditya Akundi, Eric Smith

Manufacturing & Industrial Engineering Faculty Publications

A significant increase in System-of-Systems (SoS) is currently observed in the social and technical domains. As a result of the increasing number of constituent system components, Systems of Systems are becoming larger and more complex. Recent research efforts have highlighted the importance of identifying innovative statistical and theoretical approaches for analyzing complex systems to better understand how they work. This paper portrays the use of an agnostic twostage examination structure for complex systems aimed towards developing an information theorybased approach to analyze complex technical and socio-technical systems. Towards the goal of characterizing system complexity with information entropy, work was carried …

Hiv/Aids After The Crisis: The Evolution Of An Epidemic, Emma Paras

Honors Projects

HIV and AIDS has affected the world for over four decades. In the past, a positive HIV diagnosis could very well be a death sentence, as well as signal that an individual was a social outcast. In the past ten years, however, treatments for HIV/AIDS allow a person to live a long and relatively healthy life. In addition to examining current and future trends in HIV treatment, this paper will also discuss how the virus affects different regions of the world. Particularly in certain parts of Africa, HIV/AIDS remains deadly for many who don’t have proper access to health care …

Discovery Of Phosphotyrosine-Binding Oligopeptides With Supramolecular Target Selectivity, Ana S. Pina, Leonor Morgado, Krystyna L. Duncan, Sara Carvalho, Henrique F. Carvalho, Armenio J. M. Barbosa, Beatriz De P. Mariz, Ines P. Moreira, Daniela Kalafatovic, Bruno M. Morais Faustino, Vishal Narang, Tong Wang, Charalampos G. Pappas, Isabel Ferreira, A. Cecılia A. Roque, Rein V. Ulijn

Advanced Science Research Center

We demonstrate phage-display screening on self-assembled ligands that enables the identification of oligopeptides that selectively bind dynamic supramolecular targets over their unassembled counterparts. The concept is demonstrated through panning of a phage-display oligopeptide library against supramolecular tyrosine-phosphate ligands using 9-fluorenylmethoxycarbonyl-phenylalanine-tyrosine-phosphate (Fmoc-FpY) micellar aggregates as targets. The 14 selected peptides showed no sequence consensus but were enriched in cationic and proline residues. The lead peptide, KVYFSIPWRVPM-NH2 (P7) was found to bind to the Fmoc-FpY ligand exclusively in its self-assembled state with KD = 74 ± 3 μM. Circular dichroism, NMR and molecular dynamics simulations revealed that the peptide interacts with Fmoc-FpY …

Effect Of Mechanical Systems In Combating The Schistosomiasis Snails, Sherine Ahmed El Baradei

Archived Theses and Dissertations

No abstract provided.

Novel Approaches For Enhancing Cell Survival And Function In Vivo, Ou Wang

Department of Chemical and Biomolecular Engineering: Dissertations, Theses, and Student Research

FDA has approved several cell-based therapeutics and hundreds of cell therapy clinical trials are ongoing. Cells will be a significant type of medicine after small molecule and protein drugs. However, several obstacles need to be addressed to achieve the widespread use of cellular therapeutics. The first challenge is the low efficacy of cell transplantation due to low retention, survival, integration, and function of cells in vivo. The second challenge is producing a massive number of cells for clinical treatment with cost-effectively and reproducibly technologies.

In this thesis, we proposed and investigated two approaches to address these challenges. To begin …

Computational Solutions To Exosomal Microrna Biomarker Detection In Pancreatic Cancer, Thuy T. An

School of Computing: Dissertations, Theses, and Student Research

Pancreatic cancer is the fourth leading cause of cancer death in the United States and the 5-year survival rate is only 5% to 10%. There are only a few non-specific symptoms associated with the early-stage cancer, therefore most patients are diagnosed in a late stage. Due to the lack of effective treatments and the fact that the early stage has a 39% 5-year survival rate, the biggest hope to control this disease is early detection. Therefore, discovery of effective and reliable non-invasive biomarkers for early detection of pancreatic cancer has been a major topic. Very recently, exosomal microRNAs have become …

The Application Of Mathematical Optimization And Flavor-Detection Technologies For Modeling Aroma Of Hops, Yutong Liu

Department of Food Science and Technology: Dissertations, Theses, and Student Research

In recent years, proprietary hops (Citra, Simcoe, and Mosaic) become the most sought-after hops among brewers due to their excellent aroma. However, they are restricted to the owners unless other growers purchase the costly licensing agreements. Many public hops are available to the growers without any additional costs, but their aroma is difficult to match to the proprietary hops. Although proprietary and public hop varieties are unique in their aroma profiles, all hops varieties contain similar volatile compounds, merely differ in the quantity of different individual compounds. The main objective of this thesis was to investigate the feasibility of matching …

Development And Characterization Of A Decellularized Neuroinhibitory Scaffold Containing Matrix Bound Nanovesicles, Logan Piening

Department of Agricultural and Biological Systems Engineering: Dissertations, Theses, and Student Research

Chronic low back pain (LBP) is a leading cause of disability but treatments for LBP are limited. Degeneration of the intervertebral disc leads to loss of neuroinhibitory sulfated glycosaminoglycans (sGAGs) which allows nerves from dorsal root ganglia (DRG) to grow into the core of the disc, leading to pain. Current treatments for LBP involve drugs that do not target the source of the pain and lack long term efficacy or use invasive surgeries with high complication rates. Treatment with a decellularized tissue scaffold that contains neuroinhibitory components may inhibit nerve growth and prevent disc-associated LBP. Here, a decellularized nucleus pulposus …

A Temporal Analysis Of The Microbiota And Biofouling Development On Artificial Substrates In The Port Everglades Inlet, Florida, Denise Swack

All HCAS Student Capstones, Theses, and Dissertations

A pilot project was deployed in Port Everglades Inlet, Florida that aimed to evaluate the biofilm composing the microbiome on ecologically engineered artificial substrates used to build Coastal Marine Infrastructure. In April of 2017, an Articulated Concrete Block Mattress comprised of an ecological engineered concrete substrate and a standard smooth surface control substrates were compared. This study will provide a profile on the microbiome community on artificial substrates within Port Everglades Inlet on bio-enhancing concrete-based solutions in our Coastal Marine Infrastructure. To study the microbial community, the 16s rRNA technology was used in Illumina’s high-throughput DNA sequencing. Samples were collected …

An Examination Between Laryngeal Physiology And Parkinson’S Disease: Severity And Treatment, Jillian Pelikan

University Honors Program

The purpose of this in-depth literature review is to examine the relationship between laryngeal physiology and Parkinson’s disease in terms of the severity and possible treatment. This research aims to determine the distinct characteristics of Parkinsonian speech and possible causes of these speech deficits. In addition, a specific type of Parkinson’s disease treatment, deep brain stimulation, was explored to determine effectiveness on laryngeal physiological deficits found in Parkinson’s disease patients. Through synthesizing peer reviewed journals and various studies, data was examined in order to take an in-depth look at the unique relationship between laryngeal physiology and Parkinson’s disease. Findings indicated …

Digitization Of Academic Libraries Through Cloud Environment, Sivankalai S, Virumandi A, Sivasekaran K, Jeyanthi R, M Sharmila

Library Philosophy and Practice (e-journal)

Libraries may soon be able to establish and manage their own data centres. This paradigm would allow libraries to control the apps and data stores that include sensitive and private information about their users' personal and financial information. The provisioning and management of infrastructure for a Web-based digital library present several complicated difficulties for library administrators. In this article, we address the challenges that digital libraries confront, and the efforts being made to solve those challenges. Infrastructure virtualization and cloud Environment are incredibly enticing options, but they are being challenged by the expansion of the indexed document collection, the addition …

Mit Newsletter-Special Relaunch Edition-December 2021, Anil Rana Dr.

Faculty work

No abstract provided.

Rheological Properties Of Recyclable Polymer Matrices For Advanced Composite Applications, Rahul Shankar

Dissertations

This dissertation focuses on evaluating the rheological characteristics of a variety of recyclable polymer matrices, which can compete with thermosets in a wide range of specialized applications. Studying the fundamental solid and melt-state viscoelastic properties and establishing structure-property-processing relationships is critical for the widespread adoption of these novel recyclable polymers in commercial applications. The first chapter provides an introductory overview of the different recyclable polymer matrices and their applications including high performance thermoplastics as thermoset replacements in high energy composite manufacture, multifunctional specialty thermoplastics for additive manufacturing and next generation, reprocessable covalent adaptable networks for self-healing applications. Furthermore, the important …

Contrastive Learning For Unsupervised Auditory Texture Models, Christina Trexler

Computer Science and Computer Engineering Undergraduate Honors Theses

Sounds with a high level of stationarity, also known as sound textures, have perceptually relevant features which can be captured by stimulus-computable models. This makes texture-like sounds, such as those made by rain, wind, and fire, an appealing test case for understanding the underlying mechanisms of auditory recognition. Previous auditory texture models typically measured statistics from auditory filter bank representations, and the statistics they used were somewhat ad-hoc, hand-engineered through a process of trial and error. Here, we investigate whether a better auditory texture representation can be obtained via contrastive learning, taking advantage of the stationarity of auditory textures to …

Controlled Release Of Multiple Therapeutics From Silicone Hydrogel Contact Lenses For Post-Cataract/Post-Refractive Surgery And Uveitis Treatment., Stephen A Dipasquale, Biaggio Uricoli, Matthew C Dicerbo, Thea L Brown, Mark Byrne

Henry M. Rowan College of Engineering Departmental Research

PURPOSE: This work demonstrates seven-day controlled and extended in vitro physiological flow dual release of multiple post-ocular surgery therapeutics from extended-wear contact lenses as a dropless alternative for treatment of uveitis and corneal inflammation, pain, and infection. Lens replacement each week optimizes treatment matching patient recall time with the ability to increase or decrease dosage.

METHODS: Lenses were synthesized using molecular imprinting to create lenses with macromolecular memory for diclofenac sodium (DS) and dexamethasone sodium phosphate (DMSP), as well as bromfenac sodium (BS) and moxifloxacin (MOX). Drug uptake and release were analyzed, and physical properties were measured and compared to …

Determining The Psychosocial Needs Of The Nurses Of Covid-19 Patients, Allison Stevens

ATU Theses and Dissertations 2021 - Present

Nurses are a vital element of the COVID-19 healthcare crisis and have been since the beginning of the COVID-19 response. The professional strain put on nurses included, but is not limited to: changing professional roles, rapidly changing policies and procedures, an influx of patients—particularly of high acuity, and change in workplace morale. However, nurses also had to carry the burdens of living as a member of society, family member, friend, community member, and above all, simply as a person surviving a pandemic themselves. With all of the stressors nurses have endured, it stands to reason that their psychosocial needs have …

Investigation Of Human Adipose-Derived Stem-Cell Behavior Using A Cell-Instructive Polydopamine-Coated Gelatin-Alginate Hydrogel., Settimio Pacelli, Aparna R Chakravarti, Saman Modaresi, Siddharth Subham, Kyley Burkey, Cecilia Kurlbaum, Madeline Fang, Christopher A Neal, Adam J Mellott, Aishik Chakraborty, Arghya Paul

Chemical and Biochemical Engineering Publications

Hydrogels can be fabricated and designed to exert direct control over stem cells' adhesion and differentiation. In this study, we have investigated the use of polydopamine (pDA)-treatment as a binding platform for bioactive compounds to create a versatile gelatin-alginate (Gel-Alg) hydrogel for tissue engineering applications. Precisely, pDA was used to modify the surface properties of the hydrogel and better control the adhesion and osteogenic differentiation of human adipose-derived stem cells (hASCs). pDA enabled the adsorption of different types of bioactive molecules, including a model osteoinductive drug (dexamethasone) as well as a model pro-angiogenic peptide (QK). The pDA treatment efficiently retained …

Thermometry Via Diffusion In Ferrous Core-Shell Nanoparticles For Induction Heating Applications, Hayden Carlton

Graduate Theses and Dissertations

Induction heating causes the release of enormous amounts of heat from dispersed magnetic nanoparticles. While the rate of heat transfer can be easily quantified calorimetrically, measuring the temperature of the nanoparticles on the nanoscale presents experimental challenges. Fully characterizing the temperature and thermal output of these magnetic particles is necessary to gauge overall heating efficiency and to provide a more holistic understanding of heat transfer on the nanoscale. Herein, this dissertation seeks to develop a novel nanoparticle thermometry technique, which correlates diffusion behavior in core-shell nanoparticles to local temperature. Initial measurements suggested that heating silica capped ferrous nanoparticles (SCNPs) via …

Respiratory Compensated Robot For Liver Cancer Treatment: Design, Fabrication, And Benchtop Characterization, Mishek Jair Musa

Graduate Theses and Dissertations

Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related death in the world. Radiofrequency ablation (RFA) is an effective method for treating tumors less than 5 cm. However, manually placing the RFA needle at the site of the tumor is challenging due to the complicated respiratory induced motion of the liver. This paper presents the design, fabrication, and benchtop characterization of a patient mounted, respiratory compensated robotic needle insertion platform to perform percutaneous needle interventions. The robotic platform consists of a 4-DoF dual-stage cartesian platform used to control the pose of a 1-DoF needle insertion module. The active …

Formation Of Reactive Nitrogen Species During Dichloramine Decay And Their Impact On N Nitrosodimethylamine Formation Under Drinking Water Conditions, Huong Thu Pham

Graduate Theses and Dissertations

NDMA occurrence and formation pathways in drinking water systems are reviewed and NDMA yields are compared on the basis of disinfectant type, water chemistry, and precursor category. In chloramination, despite monochloramine being the predominant species between pH 7-9, evidence suggests that dichloramine is the primary species involved in NDMA formation. This is somewhat confounding as NDMA yields are maximal at pH 9, yet at pH 9 dichloramine decays faster than it forms and hence is present at trace levels; additionally, the proposed mechanism involves a spin-forbidden incorporation of dissolved oxygen as a triplet, which is presumably kinetically slow. This review …

Complete Modeling Of The Chondrogenic Environment Under Continuous Low-Intensity Ultrasound, Heather Newell

Department of Chemical and Biomolecular Engineering: Dissertations, Theses, and Student Research

Articular cartilage is an avascular tissue that requires therapeutic intervention methods. This work answers the following: determine transducer operation to optimize the bioeffects; calculate the magnitude of pressure exerted on chondrocytes at an injury site; and confirm the theoretical findings by an animal model.

Earlier work has shown that cellular response to US is maximized at the resonance frequency of the cells. Resonance frequencies were calculated for chondrocytes in various layers. The latter configuration closest resembles in vivo conditions and the resonance occurred at 3.8±0.3 ������. The 3D model of US propagation in a rabbit knee was constructed from MRIs …

Synthesis, Characterization And Tribological Properties Of Mo-Dlc, Tirth Ashishbhai Patel

Material Science and Engineering Theses - Archive

Diamond like carbon (DLC) films have been extensively used in a wide range of applications over the last decade due to their excellent mechanical and tribological properties. Metallic elements are used to dope DLC films in an effort to overcome some DLC limitations and make it compatible to use it in larger variety of applications. This study focuses on the effect of different processing parameters on DLC deposition, and the effect of Mo content on microstructure, mechanical and tribological properties. Plasma Enhanced Chemical Vapor Deposition (PECVD) technique coupled with magnetron sputtering is used in chamber atmosphere composed of CH4 and …

Relating Linear And Rotational Accelerations With Internal Pressures Developed Inside Human Head Surrogate Models, Arthur Thomas Koster

Mechanical and Aerospace Engineering Theses - Archive

Traumatic Brain Injury (TBI) is a chronic disease process that is difficult to both detect and treat. TBI can result from blast, kinetic, sonic, and electromagnet energy sources. This research focuses on correlating the bulk acceleration of a human-like head model to the localized internal pressure developed in the coup and contrecoup regions due to variable impact loading. Damage resulting in a TBI occurs on a multiscale level from the macroscale down to the damage of each individual neuron. Obtaining a relationship between bulk acceleration and localized internal pressure will allow for further correlation to the damage done on these …

The Effects Of Snagcu Solder Interconnect Package’S Parameters On Electromigration Failure Mechanisms, Yi Ram Kim

Material Science and Engineering Dissertations - Archive

The primary concern of this dissertation is the electromigration (EM) failure mechanism found in Sn-Ag-Cu (SAC) solder alloys integrated in WCSP (wafer-level chip scale package) packaging structure and factors affecting the failure mechanisms. To the end, accelerated electromigration (EM) tests are conducted on SnAgCu (SAC) solder interconnects in wafer-level chip scale packages (WCSPs or WLCSPs) with different package structures and use-condition parameters. The package structure parameters include different under bump metallization (UBM) thicknesses, Sn grain orientation, while the various in use conditions includes pulsed direct current (DC), and alternating current (AC). The major findings made in the studies are presented …

Designing And Advancing Contrast Agents For Ultrasound-Switchable Fluorescence Imaging, Yang Liu

Bioengineering Dissertations - Archive

Fluorescence imaging is a remarkable tool for molecular targeting and multicolor imaging, but it suffers from poor resolution in centimeters-deep tissues. The recently developed ultrasound-switchable fluorescence (USF) imaging has overcome this challenge and achieved in vivo imaging with the help of the indocyanine green (ICG)-encapsulated poly(N-isopropylacrylamide) (ICG-PNIPAM) contrast agent. As USF imaging advances, there is a great demand to expand the contrast agent bank so that applications can be achieved using different types of contrast agents. Also, there is a need to improve the current ICG-PNIPAM nanogel. This study focused on improving the ICG-PNIPAM nanogel, formulating a novel contrast agent, …

Assessment Of Stormwater Infrastructure For Mitigating Flooding And Non-Point Source Pollution, Helia Farzaneh

Civil Engineering Theses - Archive

Flooding is the top natural hazard impacting coastal and inland communities in Texas. Beyond its destructive impact on rising waters in communities, flooding-induced stormwater negatively affects the quality of large bodies of water. Stormwater runs over land, washes off pollutants, and deposits them into rivers which causes water quality issues in bays and estuaries. In addition, the stormwater increases nutrients, sediments, oxygen-demanding substances, pathogens, and toxins which results in hypoxia in the aquatic system. During the last 5-6 years, severe storm events such as Tropical Storm Beta (September 2020), Tropical Storm Imelda (September 2019), Hurricane Harvey (August 2017) have caused …

Advanced Risk Models To Predict Surgical Site Infections Using Machine Learning Approaches And Risk-Adjusted Control Charts, Rabia Emhamed Al Mamlook

Dissertations

Even though most infections are treatable with antibiotics, Surgical Site Infections (SSIs) remain a significant healthcare problem as they increase hospital stays, require additional treatments, reduce a patient’s quality of life, and increase morbidity and mortality. To reduce the risks and to encourage the highest quality healthcare, it is important to measure, predict, and monitor the risk of SSIs. Preoperative prediction of SSIs is essential to facilitate the implementation of preventative strategies for high-risk patients. The overarching goal of this dissertation is to investigate new opportunities of using machine-learning (ML) to improve the accuracy and use of pre-operative prediction models …

A Multi-Dimensional Child-Langmuir Law For Any Diode Geometry, N. R. Sree Harsha, Marcus Pearlman, Jim Browning, Allen L. Garner

Electrical and Computer Engineering Faculty Publications and Presentations

While prior theoretical studies of multi-dimensional space-charge limited current (SCLC) assumed emission from a small patch on infinite electrodes, none have considered emission from an entire finite electrode. In this paper, we apply variational calculus (VC) and conformal mapping, which have previously been used to derive analytic solutions for SCLC density (SCLCD) for nonplanar one-dimensional geometries, to obtain mathematical relationships for any multi-dimensional macroscopic diode with finite cathode and anode. We first derive a universal mathematical relationship between space-charge limited potential and vacuum potential for any diode and apply this technique to determine SCLCD for an eccentric spherical diode. We …

Design For Older Adults – Functional Limitations And Human Factors Engineering, Megumi Sato Hice

Industrial, Manufacturing, and Systems Engineering Dissertations - Archive

Background: Throughout the aging process, people experience changes in functional ability and such changes can happen in physical and mental functions. As a result, older adults develop limitations in their capabilities to perform daily activities. Although many studies have done to identify functional limitations for elderly, many older adults still face negative consequences in daily living conditions due to their functional declines. One of the possible causes may be a lack of feedback or participations of elderly users in the design process. Other reason could be a lack of consideration to identify the needs for a specific task associated with …