Open Access. Powered by Scholars. Published by Universities.®
- Institution
-
- University of Nebraska - Lincoln (4198)
- Missouri University of Science and Technology (1696)
- Utah State University (1339)
- Old Dominion University (997)
- University of Arkansas, Fayetteville (992)
-
- New Jersey Institute of Technology (970)
- University of Kentucky (955)
- California Polytechnic State University, San Luis Obispo (908)
- University of Central Florida (849)
- Purdue University (836)
- Clemson University (736)
- Louisiana State University (702)
- Brigham Young University (617)
- Chulalongkorn University (589)
- Marquette University (582)
- Air Force Institute of Technology (579)
- Michigan Technological University (556)
- University of South Florida (545)
- Wright State University (543)
- Engineering Conferences International (537)
- Washington University in St. Louis (503)
- Technological University Dublin (489)
- TÜBİTAK (461)
- University of South Carolina (429)
- University of Texas at Arlington (409)
- Portland State University (388)
- National Taiwan Ocean University (381)
- University of New Mexico (369)
- University of Texas at El Paso (366)
- Virginia Commonwealth University (365)
- Keyword
-
- Engineering (475)
- Machine learning (362)
- Applied sciences (331)
- Nanoparticles (254)
- Microfluidics (215)
-
- Machine Learning (212)
- Deep learning (202)
- Optimization (192)
- Sustainability (186)
- Cancer (173)
- Water quality (171)
- Modeling (167)
- Tissue engineering (165)
- Computer Science (157)
- Biomaterials (148)
- Wastewater (141)
- Biomechanics (138)
- Simulation (137)
- Nanotechnology (136)
- Adsorption (131)
- Drug delivery (128)
- Artificial intelligence (118)
- UWRL (114)
- Deep Learning (112)
- Robotics (111)
- Biomedical Sciences (109)
- Electrospinning (109)
- Biomass (108)
- Groundwater (105)
- Doctor of Philosophy (PhD) School of Engineering (102)
- Publication Year
- Publication
-
- Theses and Dissertations (1952)
- Nebraska Tractor Tests (1347)
- Electronic Theses and Dissertations (993)
- Department of Agricultural and Biological Systems Engineering: Faculty Publications (825)
- Theses (730)
-
- USF Tampa Graduate Theses and Dissertations (522)
- Dissertations (500)
- Faculty Publications (475)
- Turkish Journal of Electrical Engineering and Computer Sciences (461)
- Master's Theses (448)
- Graduate Theses and Dissertations (394)
- Masters Theses (394)
- McKelvey School of Engineering Graduate Student Theses & Dissertations (388)
- Journal of Marine Science and Technology–Taiwan (381)
- LSU Master's Theses (370)
- All Theses (367)
- Chulalongkorn University Theses and Dissertations (Chula ETD) (353)
- Doctoral Dissertations (338)
- Electrical and Computer Engineering Faculty Research & Creative Works (326)
- Browse all Theses and Dissertations (318)
- All Dissertations (313)
- All Graduate Theses and Dissertations, Spring 1920 to Summer 2023 (307)
- Open Access Theses & Dissertations (300)
- Chemical and Biochemical Engineering Faculty Research & Creative Works (273)
- LSU Doctoral Dissertations (271)
- Biomedical Engineering Faculty Research and Publications (257)
- Dissertations and Theses (225)
- Articles (205)
- Civil and Environmental Engineering Faculty Publications (190)
- Department of Mechanical and Materials Engineering: Faculty Publications (190)
- Publication Type
Articles 5251 - 5280 of 34234
Full-Text Articles in Entire DC Network
Integration Of Neural Network And Distance Relay To Improve The Fault Localization On Transmission Lines, Linh Tran
Turkish Journal of Electrical Engineering and Computer Sciences
Power transmission lines are integral and very important components of power systems. Because of the length of these lines and the complexity of the power grids, the lines may encounter various incidents such as lightning strike, shortage, and breakage. When an incident or a fault occurs, a fast process of identification, localization, and isolation of the fault is desired. An accurate fault localization would have a great impact in reducing the restoration time of the system. One of the most popular solutions for fault detection and localization is the distance relays using the impedance-based algorithms. However, these relays are still …
Quadratic Programming Based Partitioning For Block Cimmino With Correct Value Representation, Zuhal Taş, Fahreddi̇n Şükrü Torun
Quadratic Programming Based Partitioning For Block Cimmino With Correct Value Representation, Zuhal Taş, Fahreddi̇n Şükrü Torun
Turkish Journal of Electrical Engineering and Computer Sciences
The block Cimmino method is successfully used for the parallel solution of large linear systems of equations due to its amenability to parallel processing. Since the convergence rate of block Cimmino depends on the orthogonality between the row blocks, advanced partitioning methods are used for faster convergence. In this work, we propose a new partitioning method that is superior to the state-of-the-art partitioning method, GRIP, in several ways. Firstly, our proposed method exploits the Mongoose partitioning library which can outperform the state-of-the-art methods by combining the advantages of classical combinatoric methods and continuous quadratic programming formulations. Secondly, the proposed method …
Light Sheet Microscopy Incubation Design And Control Scheme, Venkatanathan Kidambi
Light Sheet Microscopy Incubation Design And Control Scheme, Venkatanathan Kidambi
Honors Scholar Theses
The focus of the following paper is the development of a light sheet or selective plane illumination microscopy (LSM / SPIM) platform to support long duration three dimensional imaging of various cells and tissues. This paper describes the complete design and fabrication process behind the prototype, including a definition of light sheet microscopy and its differences from confocal microscopy, as well as existing open source selective plane microscopy literature and designs. The complete engineering design process as applied to the microscope design is described in detail. Specifically, this paper will focus on the development of an incubation chamber for light …
Evaluating The Role Of Magnetic Materials In Mediating The Abiotic Degradation Of Chlorinated Ethenes At Tcaap-A Using A C14-Assay, Olivia Dunn
All Theses
Among the most challenging sites to remediate are those where the groundwater is contaminated with large, dilute plumes of tetrachloroethene (PCE), trichloroethene (TCE), dichloroethene isomers (cDCE, tDCE, 1,1-DCE) and vinyl chloride (VC). Monitored Natural Attenuation (MNA) by abiotic processes may be a viable strategy, but it can be difficult to document. The overall objective of this project is to develop a deeper understanding of the role of magnetic materials in mediating abiotic degradation of low concentrations of chlorinated ethenes in aquifers. Authentic core aquifer sediment has been collected from Site A at the former Twin Cities Army Ammunition Plant (TCAAP) …
The Effects Of Social Media On Mental Health And Career Planning, Spencer A. Rowan
The Effects Of Social Media On Mental Health And Career Planning, Spencer A. Rowan
Honors Theses
Social media use is prevalent and necessary in society—nearly anything can be accomplished with a mobile device or smartphone. Among the US population, two thirds of American adults admit to using social media (Perrin, 2015) and in 2022, Georgiev (2023) found Americans spent an average of two and a half hours daily on social media. Furthermore, social media use is tied to mental well-being, work confidence levels, and feelings of being an imposter (Johnson et al., 2020; Uram & Skalski, 2022; Hernandez & Chalk, 2021; Myers, 2021; Ramm, 2019).
This project examined the role of social media use among college …
Comparison Of Facial Emotion Recognition Models Using Deep Learning, Arsany Hanin
Comparison Of Facial Emotion Recognition Models Using Deep Learning, Arsany Hanin
LSU New Orleans Theses and Dissertations
Facial emotion recognition is a widely studied area with applications in diverse domains such as human-computer interaction, affective computing, and social robotics. This thesis aims to improve the accuracy of facial emotion recognition models by incorporating a second neural network trained on original probabilities and probability transformation, while also comparing the performance of different techniques. The thesis begins with a thorough review of available datasets and technologies used for data collection, highlighting the challenges associated with these datasets. A detailed analysis of various facial emotion detection models, including the baseline model and its different architectures, is presented. The thesis also …
Engineered Material Systems For Mimicking Tissue And Disease, Margrethe Ruding
Engineered Material Systems For Mimicking Tissue And Disease, Margrethe Ruding
McKelvey School of Engineering Graduate Student Theses & Dissertations
This thesis comprises two studies involving design and application of soft material systems. The goal of the first study was to design, fabricate, and characterize hydrogel lattice structures with consistent, controllable, anisotropic mechanical properties. Lattices, based on four types of unit cells (cubic, diamond, vintile, and Weaire-Phelan), were printed using stereolithography (SLA) of polyethylene glycol diacrylate (PEGDA). In order to create structural anisotropy in the lattices, unit cell design files were scaled in one direction by a factor of two in each layer and then printed. The mechanical properties of the scaled lattices were measured in shear and compression and …
Dpd Guided Insight On The Formation Process Of Polyethersulfone Membranes By Nonsolvent Induced Phase Separation And The Effects Of Additives, Eric Ledieu
Graduate Theses and Dissertations
Dissipative particle dynamics (DPD), a coarse grain simulation method, was applied to the membrane formation process of non-solvent induced phase separation (NIPS) to gain further insight on the mechanism of certain variables and how they affect the final morphology. NIPS involves two solutions, an organic polymer dissolved in an organic solvent colloquially called the dope and an aqueous coagulation bath, brought into contact with one another. The solvents then mix, causing the polymer to fall out of solution as an asymmetric membrane with a dense surface layer and a more open subsurface layer in response to the decreasing solubility. Polyethersulfone …
Effect Of Human Decellularized Skeletal Muscle On Recovery From Volumetric Muscle Loss Injury, Jacob Schluns
Effect Of Human Decellularized Skeletal Muscle On Recovery From Volumetric Muscle Loss Injury, Jacob Schluns
Graduate Theses and Dissertations
Volumetric muscle loss (VML) overwhelms muscle’s robust capacity for regeneration. A key event in the etiology of VML injury is the bulk loss of structural cues provided by the underlying extracellular matrix (ECM). While muscle is a highly structured tissue, with cell and ECM alignment in the direction of contractile force production, the impact of scaffold alignment on recovery remains unclear. Bulk human decellularized skeletal muscle (DSM) tissues were sectioned into 10 x 1-2 mm fibers. VML defects were repaired using multi-fiber implants consisting of approximately 8 fibers per defect arranged into two layers. Fibers were oriented 1) to the …
Automation Of Life Cycle Assessment, Jacob Hickman
Automation Of Life Cycle Assessment, Jacob Hickman
Graduate Theses and Dissertations
An automation program, named Jacob LCA, was created to help perform life cycle assessment (LCA). The program uses a template file to perform controlled and consistently ordered actions with the LCA program, SimaPro, and effectively removes the need for manual user input. It can be set to run using data from one or more life cycle inventory (LCI) files, which allows for rapid iteration and testing of data. It also partially addresses some of the limitations of LCA by establishing a procedure through which temporal and spatial variations in data can be integrated into LCI files and then passed to …
Formulation And Optimization Of Algae-Filled Polylactic Acid Thermoplastic Compounds For Improved Biodegradation, Sydney A. Cole
Formulation And Optimization Of Algae-Filled Polylactic Acid Thermoplastic Compounds For Improved Biodegradation, Sydney A. Cole
Honors Theses
Conventional plastics derived from non-renewable petrochemicals – especially from fossil reserves – have become an integral part of human life because their structure can be chemically manipulated to obtain a wide range of properties and geometries necessary in nearly all industries. The volume and rate at which petroleum plastics are produced, used, and discarded has incited several significant issues related to human health, environmental conservation, and ecological biodiversity. To address these issues, many institutions have begun investigating solutions in both the development and end-oflife phases of plastic production and waste. In this thesis, a Chlorella-dominated algae mixture is dried and …
Automated Segmentation Of Autofluorescence Lifetime Images Using A Convolutional Neural Network, Nicole Hooten
Automated Segmentation Of Autofluorescence Lifetime Images Using A Convolutional Neural Network, Nicole Hooten
Biomedical Engineering Undergraduate Honors Theses
Chronic wounds affect nearly 1 out of every 50 people in the United States, decreasing quality of life and putting people with potential comorbidities at high risk for obtaining an infection. Wound healing progress in clinical settings is measured by tracking wound size and there are currently no non-invasive, quantitative measurement techniques. Previous studies have proposed nicotinamide adenine dinucleotide (NADH) autofluorescence lifetime (FLIM) imaging of the wound edge as a method to quantify the wound healing process by connecting the role of NADH in cellular metabolism to wound healing stage. However, evaluation of FLIM images is heavily subjective, as a …
Development Of A Computational Model To Investigate Pathways And The Effects Of Treatment In Fanconi Anemia, Sabrina Kellett
Development Of A Computational Model To Investigate Pathways And The Effects Of Treatment In Fanconi Anemia, Sabrina Kellett
Biological Sciences Undergraduate Honors Theses
Fanconi Anemia (FA) is a rare type of anemia that is not easily studied and can have very detrimental effects. This disease compromises the bone marrow, resulting in decreased hemopoiesis. Symptoms of FA also include abnormalities in the brain and spinal cord, incorrect formation of the kidneys, abnormal formation of the heart and lungs, and a dramatically increased risk of developing cancer. FA can be caused by various mutations in any of the 22 genes that encode for proteins involved in what is called the FA DNA repair pathway. In healthy individuals, this pathway specifically repairs interstrand cross-links (ICLs) recognized …
Ranking Highway Transportation Asset Criticality Through Stakeholder Input Using The Analytical Hierarchy Process (Ahp), Kwadwo Amankwah-Nkyi
Ranking Highway Transportation Asset Criticality Through Stakeholder Input Using The Analytical Hierarchy Process (Ahp), Kwadwo Amankwah-Nkyi
Graduate Theses and Dissertations
The transportation system is especially vulnerable to natural and human-made disasters which can have effects on mobility, safety, and the economy. This thesis presents a method to rank transportation assets based on their criticality to the transportation system by uniquely gathering stakeholder input on criticality criteria weights. This serves as a typical first step in vulnerability and resilience assessments. Six criteria were used to estimate asset criticality: Annual Average Daily Traffic (AADT), roadway classification, freight output, tourism output, Social Vulnerability Index (SoVI), and redundancy. Then, the criteria are combined via stakeholder input using a weighted ranking scheme called the Analytical …
Time-Dependent Wetting Behavior Of Hydrogels, Amir Kashani
Time-Dependent Wetting Behavior Of Hydrogels, Amir Kashani
UNLV Theses, Dissertations, Professional Papers, and Capstones
Hydrogels are 3-D polymers with hygroscopic properties that enable them to absorb and retain large amounts of water. In many applications such as biomedical applications, including drug delivery, wound healing, tissue engineering, biosensors, and contact lenses, agriculture, food and beverage, cosmetics, and environmental, hydrogels also need to maintain a high degree of wetting in order to ensure effective functionality and interaction with surrounding fluids or tissues in desired applications. The combination of wetting and absorptive behavior of hydrogels that are often encountered in biomedical, biological, industrial and the mentioned applications presents a challenging physical problem that is not completely understood. …
Mathematical Modeling: Finite Element Analysis And Computations Arising In Fluid Dynamics And Biological Applications, Jorge Reyes
Mathematical Modeling: Finite Element Analysis And Computations Arising In Fluid Dynamics And Biological Applications, Jorge Reyes
UNLV Theses, Dissertations, Professional Papers, and Capstones
It is often the case when attempting to capture real word phenomena that the resulting mathematical model is too difficult and even not feasible to be solved analytically. As a result, a computational approach is required and there exists many different methods to numerically solve models described by systems of partial differential equations. The Finite Element Method is one of them and it was pursued herein.This dissertation focuses on the finite element analysis and corresponding numerical computations of several different models. The first part consists of a study on two different fluid flow models: the main governing model of fluid …
A One-Dimensional Analysis Of A Microbial Fuel Cell For Efficient Acetate Removal And Power Density Output, David Rouhani
A One-Dimensional Analysis Of A Microbial Fuel Cell For Efficient Acetate Removal And Power Density Output, David Rouhani
UNLV Theses, Dissertations, Professional Papers, and Capstones
Microbial fuel cells (MFCs) are electrochemical devices that utilize microorganisms to convert organic matter into electrical energy. MFCs have been discussed to have potential application for sustainable wastewater treatment due to their ability to generate electricity while simultaneously treating contaminated water. To optimize MFC performance, numerical models can be used to understand the complex electrochemical and biological processes occurring in the system. In this study, a numerical model was developed to simulate the performance of MFCs under varying operating conditions and to investigate the performance of a MFC for treating wastewater fuel. More specifically, the MFC was modeled to oxidize …
Preparing Homogenous Composites Of Collagen And Cellulose Nanocrystals For Tissue Engineering Research, Zachary Stanley
Preparing Homogenous Composites Of Collagen And Cellulose Nanocrystals For Tissue Engineering Research, Zachary Stanley
Biological and Agricultural Engineering Undergraduate Honors Theses
Advancements in medicine and our understanding of stem cells have led to a greater emphasis on further developing research focused on tissue engineering. This research has led to the rise of both two-dimensional and three-dimensional scaffolds that can be utilized to repair bone, skin, vascular, and potentially even nervous tissue. One of the prominent compounds used in modern scaffolds is collagen-based hydrogels due to their low antigenicity and ability to provide structure to cells. There is potential to further improve upon this three-dimensional scaffold by incorporating cellulose nanocrystals (CNCs) into a composite hydrogel with collagen. The addition would increase the …
Analyzing Energy Use From Arkansas Public School Buildings, Oscar Morton
Analyzing Energy Use From Arkansas Public School Buildings, Oscar Morton
Biological and Agricultural Engineering Undergraduate Honors Theses
Energy is a key global resource in society and greenhouse gas (GHG) emissions related to the consumption of energy have detrimental effects on the planet. With energy consumption increasing, exponential population growth, and diminishing natural resources necessary for energy production, the relevance of energy efficiency is dramatically increasing. In this project, I analyzed energy usage data from a set of public school buildings from one school district in northwest Arkansas from 2018, before targeted energy efficiency practices were implemented, through 2022 to see if energy usage changed over this short period. The objectives of analyzing energy data were to determine …
Closed-Loop, Recyclable Plastics From Ethyl Cyanoacrylate, Allison Joy Christy
Closed-Loop, Recyclable Plastics From Ethyl Cyanoacrylate, Allison Joy Christy
Boise State University Theses and Dissertations
Ethyl cyanoacrylate, commonly known as super glue, has held a prominent role as an adhesive for decades due to its propensity to rapidly polymerize into poly(ethyl cyanoacrylate) (PECA) under ambient conditions. Ethyl cyanoacrylate monomers and their resulting PECA polymers are bio-friendly, which has allowed them to be used as medical adhesives and to be applied to drug delivery systems. However, PECA has not been used as a plastic material due to the perceived difficulty of handling the ethyl cyanoacrylate monomer. Here, we present a novel PECA plastic that displays thermal stability and tensile strength values that are comparable to atactic …
Battery Design, Construction, And Characterization For Small Motor Use Focusing On Anodic Zinc For Electron Flow, Amber Veach
Battery Design, Construction, And Characterization For Small Motor Use Focusing On Anodic Zinc For Electron Flow, Amber Veach
Chemical Engineering Undergraduate Honors Theses
This thesis explores the construction, characterization, and application of anodic zinc batteries for powering a small electric motor for the ChemE Car competition. Two zinc galvanic cell batteries were studied: zinc-carbon and zinc-air batteries. Prototype batteries were constructed and tested for voltage, amperage, and power production. In the zinc-carbon trials, a 3:1 mixture of manganese dioxide and graphite was determined to be the best cathode for power production. The size which allowed for sufficient power while maintaining the smallest footprint on the car was a zinc can six cm tall and two cm in diameter. Analysis of paper zinc-air battery …
Interactions And Phenomena Between Disodium Cromoglycate And Polyelectrolytes, Brandon Tipton
Interactions And Phenomena Between Disodium Cromoglycate And Polyelectrolytes, Brandon Tipton
Chemical Engineering Undergraduate Honors Theses
The interactions between polyelectrolytes and oppositely charged macroions have been widely studied, but few reports have been made on the interaction between chromonic mesogens and polyelectrolytes. Here, we report on the formation of liquid crystalline coacervates achieved by the liquid-liquid phase separation of an aqueous solution of negatively charged liquid crystal and polycations. As well as the occurrence of tactoids that form in the absence of these interactions. The liquid crystal that is experimented with is disodium cromoglycate, better known as DSCG. This acts as a negative charge that is paired with a variety of positively charged polyelectrolytes. The first …
Characterization And Manipulation Of Double-Stranded Dna Using Atomic Force Microscopy, Lauren Skartvedt
Characterization And Manipulation Of Double-Stranded Dna Using Atomic Force Microscopy, Lauren Skartvedt
Mechanical Engineering Undergraduate Honors Theses
An atomic force microscope (AFM) is used to scan high-resolution images on the nano scale. The lambda DNA used for this project are 48,502 base pairs in length and are double-stranded. This project utilizes the NanoSurf Core AFM in order to characterize and manipulate strands of lambda DNA which have been deposited on a mica surface. The deposition process of the DNA on the mica surface was developed by the National Institute of Standards and Technology and the University of Colorado - Boulder. The AFM is used in imaging mode to scan the mica surface to locate the DNA. When …
Probing The Structure Of Water On Surfaces: From Water Absorption To Ice Nucleation, Jiarun Zhou
Probing The Structure Of Water On Surfaces: From Water Absorption To Ice Nucleation, Jiarun Zhou
All Dissertations
Water, essential for all life forms, is the most abundant, simple, yet mysterious molecule in the world. This molecule, consisting of only three atoms, behaves in unexpectedly different ways with the change of environment. In the past, studies of water under different conditions (temperature, pressure, on the surfaces, with confinement) have been conducted using experimental and computational methods. However, the influence of a given environment on water properties is yet to be fully understood. This dissertation studies water at complex interfaces (surfaces with various chemistry and physics properties) in both the liquid and crystalline states. Various heterogeneous systems used to …
Decision Support Issues In Automated Driving Systems, William N. Caballero, David Ríos Insua, David Banks
Decision Support Issues In Automated Driving Systems, William N. Caballero, David Ríos Insua, David Banks
Faculty Publications
Machine learning and computational processing have advanced such that automated driving systems (ADSs) are no longer a distant reality. Many automobile manufacturers have developed prototypes; however, there exist numerous decision support issues requiring resolution to ensure mass ADS adoption. In the coming decades, it is likely that production ADSs will only be partially autonomous. Such ADSs operate within predetermined conditions and require driver intervention when they are violated. Since forecasts of their 20-year market penetration are relatively low, ADSs will likely operate in heterogeneous traffic characterized by vehicles of varying autonomy levels. Under these conditions, effective decision support must consider …
Tumor Targeting Gold Nanoparticles For Delivery Of Rna And Dna Oligonucleotide Therapies For Glioblastoma., Nicholas Allen
Tumor Targeting Gold Nanoparticles For Delivery Of Rna And Dna Oligonucleotide Therapies For Glioblastoma., Nicholas Allen
Electronic Theses and Dissertations
Glioblastoma (GBM) brain tumors are highly aggressive gliomas due to genetic and cellular heterogeneity. Current GBM treatment consists of surgical resection of the tumor combined with radio- or chemo-therapies. While these treatments have increased the life expectancy for GBM patients up to 20 months, they have had little effect on the 5-year survival rate. The complex cellular and genetic composition of the tumor makes current treatments less effective long term. One approach to developing more effective GBM treatments is to customize nanoparticle-based drug delivery systems that can directly target the aberrant gene expression patterns within a particular GBM tumor. Delivery …
Pyrolysis—A Tool In The Wastewater Solids Handling Portfolio, Not A Silver Bullet: Benefits, Drawbacks, And Future Directions, Patrick J. Mcnamara, Zhongzhe Liu, Yiran Tong, Hari Santha, Lynne Moss, Daniel Zitomer
Pyrolysis—A Tool In The Wastewater Solids Handling Portfolio, Not A Silver Bullet: Benefits, Drawbacks, And Future Directions, Patrick J. Mcnamara, Zhongzhe Liu, Yiran Tong, Hari Santha, Lynne Moss, Daniel Zitomer
Civil and Environmental Engineering Faculty Research and Publications
Pyrolysis is the process whereby carbonaceous materials, such as biosolids, are heated between 400°C and 900°C in the absence of oxygen. Three main products are generated: a solid product called biochar, a py-liquid that consists of aqueous phase and non-aqueous phase liquid, and py-gas. The biochar holds value as a beneficial soil amendment and sequesters carbon. The py-liquid is potentially hazardous and needs to be dealt with (including potentially reducing it on-site via catalysis or thermal oxidation). Py-gas can be used on-site for energy recovery. Pyrolysis has gained recent interest due to concern over per- and polyfluoroalkyl substances (PFAS) in …
The Influence Of Myoblast Implantation On Arteriogenesis In Mice With Diet-Induced Obesity, Rayana Gutierrez
The Influence Of Myoblast Implantation On Arteriogenesis In Mice With Diet-Induced Obesity, Rayana Gutierrez
Biomedical Engineering
Peripheral arterial occlusive disease (PAOD) is characterized by atherosclerosis, which is the buildup of plaque, consisting largely of cholesterol, in the arterial walls. This plaque accumulation eventually blocks blood flow to the limbs, causing symptoms such as intermittent claudication and tissue death in cases of critical limb ischemia. The body compensates for the reduced perfusion by enlarging pre-existing bypass arteries, known as collaterals, in a process called arteriogenesis. However, in many cases, collateral networks constructed through arteriogenesis fail to enlarge sufficiently or function effectively in patients. Therefore, the development of a therapeutic intervention specifically targeting this process would offer a …
Floating Offshore Wind Turbine Project, Courtney Huitt, Cormack Williams
Floating Offshore Wind Turbine Project, Courtney Huitt, Cormack Williams
Civil and Environmental Engineering
Offshore wind is a developing industry in the Central Coast with the advent of the future offshore wind project planned off the north coast of San Luis Obispo County. This senior design project aligns with the recently leased wind energy project as a detailed study on the structural design, geotechnical design, and construction of a single 14 MW floating offshore wind turbine (FOWT) located 40 km NW of Morro Bay (NOAA buoy 46028). A preliminary design of a spar FOWT is presented in this project as a solution to the rapidly increasing water depth off the coast of Morro Bay, …
Engineering Of Microparticle Encapsulated Antioxidant To Mitigate Oxidative Stress In Vitro And In Vivo, Kayla Ney
Department of Agricultural and Biological Systems Engineering: Dissertations, Theses, and Student Research
Chronic low back pain (cLBP) is one of the leading causes of years lived with disability in the United States. Current treatments for cLBP have variable results across the patient population, and many patients struggle to find consistent relief. Most current treatments focus on the symptom of pain, not the root cause. In painful degenerated discs, oxidative stress and inflammation function in a vicious cycle and perpetuate degeneration, damage, and pain. Therefore, oxidative stress and inflammation are important targets in addressing the source of pain. This work characterizes an antioxidant, BuOE, encapsulated in a chondroitin sulfate microparticle as a novel …