Digital Commons Network^™

Investigation Of Placement Of Polyethylenimine Within Thin Film Composite Reverse Osmosis Membranes For Enhanced Anti-Fouling Properties, Taylor F. Austin

Master's Theses

Fresh water scarcity is an alarming issue for communities across the globe. The development of water recycling and reuse technologies has become crucial in expanding the limited water resources. Reverse osmosis (RO) is among the key processes that can treat wastewater to meet potable water reuse standards. Despite the advancements in RO membrane technologies, many challenges persist regarding the operation and maintenance of RO membranes, such as membrane fouling. Extensive research investigations have focused on developing RO membrane modifications to combat the decreased performance due to fouling. Polyethylenimine (PEI) is a promising polymer used for enhancing the anti-fouling properties of …

Effects Of Individual Strategies For Resource Access On Collaboratively Maintained Irrigation Infrastructure, Jordan L. Stern, Afreen Siddiqi, Paul N. Grogan

Faculty Publications

Built infrastructure for water and energy supply, transportation, and other such services underpins human well-being and socioeconomic development. A fundamental understanding of how infrastructure design and user strategies interact can guide important design decisions as well as policy formulation for ensuring long-term infrastructure viability in conjunction with improved individual user benefits. In this work, an agent based model (ABM) is developed to study this issue for the specific case of irrigation canals. Cooperatively maintained irrigation canals serve essential roles in sustaining agriculture-based economies in many regions. Canal system design can strongly affect benefits derived by distributed users, regional agricultural output, …

Filters For Fiji: A Modified Cracker Box Biosand Filter For Rural Fiji, Geneva Newell, Cameron Lowrey, Thomas Burt, Lexie Caterine

Civil and Environmental Engineering

Water quality remains a major issue throughout rural Fiji, as current solutions rely on outside organizations providing money or technology. The goal of Filters for Fiji’s research was to develop a sustainable water filtration method for the people of rural Fiji, through ethnographic and biological research. In order to be sustainable, the filter had to be inexpensive (less than USD$15), simply built and maintained, and suitable for the end-user. The driving question of the research was: can a plastic, modified biosand filter be constructed from materials that could be sourced locally in rural Fijian communities? To answer this question, feedback …

Enhancing Construction Safety Training Of Bridges Using Augmented Reality And Virtual Reality, Mohamed Sherif Elrifaee

Theses and Dissertations

Infrastructure development projects are widely acknowledged as some of the most complex and challenging projects to undertake. The construction of bridges, in particular, has proven to be a significant safety risk for workers, with a considerable number of accidents reported on construction sites. There is a lack of comprehensive training programs specifically designed for bridge construction safety, and only a few studies have explored the use of both AR and VR to enhance safety training in construction. As such, this research aims to improve the safety of bridge construction sites through the implementation of Augmented Reality (AR) and Virtual Reality …

Deconstructed Plastic Substrate Preferences Of Microbial Populations From The Natural Environment, Lindsay I. Putman, Laura G. Schaerer, Ruochen Wu, Daniel G. Kulas, Ali Zolghadr, Rebecca Ong, David Shonnard, Stephen Techtmann

Michigan Tech Publications, Part 1

Over half of the world's plastic waste is landfilled, where it is estimated to take hundreds of years to degrade. Given the continued use and disposal of plastic products, it is vital that we develop fast and effective ways to utilize plastic waste. Here, we explore the potential of tandem chemical and biological processing to process various plastics quickly and effectively. Four samples of compost or sediment were used to set up enrichment cultures grown on mixtures of compounds, including disodium terephthalate and terephthalic acid (monomers of polyethylene terephthalate), compounds derived from the chemical deconstruction of polycarbonate, and pyrolysis oil …

Surface Characterization Of Low-Density Polyethylene Mulch, Risha Shah

Materials Engineering

Plastic pollution in aquatic systems has traditionally been highlighted in past and current research due to the increase in plastic production every year. Unfortunately, quantitative and qualitative data regarding plastic pollution on land systems such as agricultural mulch is limited. Agricultural mulch breaks down into macroplastics and then degrades into microplastics. The microplastics investigated in this study are all secondary microplastics: microplastics that form due to weathering of larger fragments of plastic. Weathering can occur due to a variety of factors; however, UV radiation and mechanical weathering have been the factors of focus on most current research in microplastic formulation. …

Bruxism Biofeedback Device, Claire A. Dossey, Errin S. Abasolo, Isabelle A. Starr

General Engineering

This paper aims to summarize the design process for a biofeedback bruxism device, covering the necessary background research, engineering requirements, design process, prototyping, manufacturing, and testing for the device. The purpose of this project was to design an engineering solution for the treatment of bruxism. This entails both measuring and significantly reducing clenching and grinding during sleep, as many current solutions may reduce symptoms of the disorder, but do not treat bruxism itself. Engineering requirements included biocompatibility, size and weight, electrical safety, and easy of use and comfort. Many design options were proposed, and a Pugh Matrix was used to …

Clinical Utility Of Mesenchymal Stem/Stromal Cells In Regenerative Medicine And Cellular Therapy, Vitali V. Maldonado, Neel H. Patel, Emma E. Smith, C. Lowry Barnes, Michael P. Gustafson, Raj R. Rao, Rebekah M. Samsonraj

Biomedical Engineering Faculty Publications and Presentations

Mesenchymal stem/stromal cells (MSCs) have been carefully examined to have tremendous potential in regenerative medicine. With their immunomodulatory and regenerative properties, MSCs have numerous applications within the clinical sector. MSCs have the properties of multilineage differentiation, paracrine signaling, and can be isolated from various tissues, which makes them a key candidate for applications in numerous organ systems. To accentuate the importance of MSC therapy for a range of clinical indications, this review highlights MSC-specific studies on the musculoskeletal, nervous, cardiovascular, and immune systems where most trials are reported. Furthermore, an updated list of the different types of MSCs used in …

Composite Solid Rocket Motor Case Optimization With Matlab Genetic Algorithm, Aleksandr Breit

Master's Theses

This study utilizes MATLAB genetic algorithm (GA) to perform optimization on a solid rocket motor (SRM) chamber structure. The (SRM) structure is modelled as a cylindrical composite laminate where unidirectional fiber orientations are the primary design variable in the optimization problem formulation. Additional design variables such as chamber length, diameter, and internal pressure are altered along with the ply angles to minimize the safety margin towards a near-zero value and encourage efficient layup design. Classical lamination theory with Tsai-Wu failure criterion are used to calculate ply-level safety margins. A thickness minimization scheme is employed to reduce the ply count from …

Assessing The Resilience Of Mycorrhizal Networks Following Central Tree Removal, Deon Lillo

Master's Theses

Mycorrhizal networks (MNs), or the networks of fungal mycelia that connect plants to each other, are vital in contributing to the well-being of ecosystems. They not only assist in the transport of nutrients across an ecosystem, but also help protect an ecosystem from disease and adverse conditions. However, more research into these networks is needed and modelling these networks as graphs can help us achieve this. By applying centrality analysis and performing k-core partitioning on these networks, we are able to identify the trees that are most important and central to a MN and observe the effects of removing these …

Integration Of Environmental Sustainability And Decision Making: Case Studies Of Civil Infrastructure, Sussan Moussavi

Department of Civil and Environmental Engineering: Dissertations, Theses, and Student Research

Sustainable development is important in the planning and design of critical civil infrastructure systems. However, decision making related to these systems currently lacks meaningful sustainability considerations. To fill this gap, this research explores the life cycle impacts of wastewater and energy infrastructure using case studies, life cycle assessment methodologies, and stakeholder discussions. Environmental and economic impacts, which are more commonly quantified, as well as more difficult to quantify societal factors, are explored. The goal of this research is to help inform decision making and facilitate the consideration of the three pillars of sustainability (e.g., economic, environmental, and social) during the …

An Engineering Approach For Evaluating The Lifetime Experience Of Sex Trafficking Victimization, Kimberly Starr Nagulpelli

Dissertations

This research is an original approach that applies industrial engineering and operations research tools to the sociological problem of sex trafficking victimization. Such an approach enables quantitative evaluation of the impacts on an individual’s lifetime by anti-trafficking efforts and public policies.

A fully interconnected, lifetime model for the experience of sex trafficking victimization is defined as the result of a comprehensive review of literature. Beginning with victimization risk, the defined model is an anticipatory tool to understand the incidences and consequences to individuals during their lifetime. This research develops the model further into a Discrete-Time Markov Chain (DTMC) with definitions …

Wave Energy Converters With Rigid Hull Encapsulation: A Review, Mahmodul Hasan Maheen, Yingchen Yang

Mechanical Engineering Faculty Publications

Highlights

• WECs with rigid hull encapsulation are water-tight and robust.

• Diverse internally embedded power take-off designs are summarized.

• Various mechanisms and strategies for frequency tuning are formulated.

• Typical WEC testing methods are discussed.

• Some future research considerations are suggested.

Abstract

Ocean wave energy has a great potential in mitigating energy and sustainability crises of the 21st century. The lack of mature and cost-competitive wave energy converter (WEC) technologies, however, has become a major roadblock for WEC products entering the marketplace. A harsh ocean environment, which includes extreme waves, strong biological activities, and chemical transformations, adds to the maintenance cost and …

Neural Correlates Of Post-Traumatic Brain Injury (Tbi) Attention Deficits In Children, Meng Cao

Dissertations

Traumatic brain injury (TBI) in children is a major public health concern worldwide. Attention deficits are among the most common neurocognitive and behavioral consequences in children post-TBI which have significant negative impacts on their educational and social outcomes and compromise the quality of their lives. However, there is a paucity of evidence to guide the optimal treatment strategies of attention deficit related symptoms in children post-TBI due to the lack of understanding regarding its neurobiological substrate. Thus, it is critical to understand the neural mechanisms associated with TBI-induced attention deficits in children so that more refined and tailored strategies can …

Motion-Resistant Pulse Oximetry, Ludvik Alkhoury

Dissertations

The measurement of vital signs ? such as peripheral capillary oxygen saturation (SpO₂) and heart rate (HR) levels ? by a pulse oximeter is studied. The pulse oximeter is a non-invasive device that measures photoplethysmography (PPG) signals and extracts vital signs from them. However, the quality of the PPG signal measured by oximetry sensors is known to deteriorate in the presence of substantial human and sensor movements contributing to the measurement noise. Methods to suppress such noise from PPG signals measured by an oximeter and to calculate the associated vital signs with high accuracy even when the wearer …

Biomechanical And Psychophysical Underpinnings Of Balance Dysfunction In Individuals With Traumatic Brain Injury, Naphtaly Ehrenberg

Dissertations

Falls are a major burden on healthcare infrastructure, especially in older adults and even more so in older individuals that are living in institutions. According to data from the Centers for Disease Control and Prevention (CDC), from 2010 to 2020, unintentional falls were the leading cause of nonfatal emergency department visits for all age groups except among individuals from 15-24 years of age, where unintentional falls ranked a very close second to being unintentionally struck by or against. Among older individuals living in the community, approximately 30-35% fall at least once in a given year, and around three times as …

Importance Of Vegetation In Tsunami Mitigation: Evidence From Large Eddy Simulations With Fluid-Structure Interactions, Abhishek Mukherjee

Dissertations

Communities worldwide are increasingly interested in nature-based solutions like coastal forests for the mitigation of coastal risks. Still, it remains unclear how much protective benefit vegetation provides, particularly in the limit of highly energetic flows after tsunami impact. The present thesis, using a three-dimensional incompressible computational fluid dynamics model with a fluid-structure interaction approach, aims to quantify how energy reflection and dissipation vary with different degrees of rigidity and vegetation density of a coastal forest.

In this study, tree trunks are represented as cylinders, and the elastic modulus of hardwood trees such as pine or oak is used to characterize …

Development Of Non-Viral Nano-Carriers For Gene Delivery And Covid-19 Vaccines, Zhongyu Li

Dissertations

Gene therapy is one of the most promising medical fields with the potential to effectively advance the treatment of difficult diseases by producing therapeutic proteins or repairing defective gene sequences. However, gene therapy presents severe challenges in delivery including renal clearance, phagocytosis, enzymatic degradation, protein absorption, and cellular internalization barriers, which have been barriers for translation into the clinic. Naked nucleic acids, with their intrinsic negative charge, electrostatically repulse the anionic cell membrane, preventing cellular uptake. Also, they are considered foreign genetic material when introduced into the body and are rapidly cleared by the reticuloendothelial system or degraded by nucleases, …

Development Of Novel Nanocarbon Based Materials And Membranes With Enhanced Biocidal Capabilities For Clean Water Generation, Indrani Gupta

Dissertations

Water scarcity is one of the major challenges facing humanity today, driven by population growth, economic development, and dietary shifts towards more water-intensive animal products. To address this issue, efficient water resource management and recycling of wastewater are essential. However, around 80% of wastewater globally is discharged into water bodies without treatment, posing a risk to ecosystems and human health. Pathogens, or harmful microorganisms, are a primary cause of water impairment and the transmission of waterborne diseases, leading to increased mortality rates. Traditional methods of treating pathogens involve the use of radiation or chemical disinfectants. Nonetheless, these methods have drawbacks, …

Mathematical And Machine Learning Approaches For Classification Of Protein Secondary Structure Elements From Cα Coordinates, Ali Sekmen, Kamal Al Nasr, Bahadir Bilgin, Ahmet Bugra Koku, Christopher Jones

Computer Science Faculty Research

Determining Secondary Structure Elements (SSEs) for any protein is crucial as an intermediate step for experimental tertiary structure determination. SSEs are identified using popular tools such as DSSP and STRIDE. These tools use atomic information to locate hydrogen bonds to identify SSEs. When some spatial atomic details are missing, locating SSEs becomes a hinder. To address the problem, when some atomic information is missing, three approaches for classifying SSE types using Ca atoms in protein chains were developed: (1) a mathematical approach, (2) a deep learning approach, and (3) an ensemble of five machine learning models. The proposed methods were …

Molecular Simulations Of Mechanical Effects Of Adsorption In Gas And Liquid Phases, Alina Emelianova

Dissertations

Fluids adsorbing in nanoporous solids cause high pressures that affect the solids and the properties of the fluids themselves. This work explores the mechanical response of solids to the adsorption of gas and liquid. Chapter 1 outlines the current achievements in investigating the mechanical response of adsorbents to the adsorption process, specifically, the computational approaches to predict adsorption-induced deformation. Chapter 2 introduces the theoretical and computational methods employed in this work. Chapters 3-7 address the design and application of the computational techniques for such prediction in different systems: mesoporous silica, microporous zeolites, and metal-organic frameworks, and Chapter 8 focuses on …

Engineering A Multicompartment In Vitro Model For Dorsal Root Ganglia Phenotypic Assessment, Sydney M. Caparaso, Adan Redwine, Rebecca A. Wachs

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Despite the significant global prevalence of chronic pain, current methods to identify pain therapeutics often fail translation to the clinic. Phenotypic screening platforms rely on modeling and assessing key pathologies relevant to chronic pain, improving predictive capability. Patients with chronic pain often present with sensitization of primary sensory neurons (that extend from dorsal root ganglia [DRG]). During neuronal sensitization, painful nociceptors display lowered stimulation thresholds. To model neuronal excitability, it is necessary to maintain three key anatomical features of DRGs to have a physiologically relevant platform: (1) isolation between DRG cell bodies and neurons, (2) 3D platform to preserve cell–cell …

The Influence Of Environmental Tax And Technology On Different Air Pollution Emissions In Oecd Countries, Malak Ali Assaf

BAU Journal - Creative Sustainable Development

Although countries continuously employ taxation and technological measures to control air pollution in the Organization for Economic Co-operation and Development, the results of these practices should be evaluated to determine whether they reach their intended outcomes. This study used panel autoregressive distributed lag model to establish how environmental taxes and technology affects the emission of air pollutants (nitrogen oxides, Carbon dioxide, and particulate matter 2.5). Using secondary data present in the OECD Database and The World Bank, EViews panel was derived to create 3 model in which each of the three variables would be sufficiently explained by environmental tax, abatement …

Discussing Different Images Of Pharmaceutical Company, Roula Afif Bou Assi, Ola Bazaza

BAU Journal - Creative Sustainable Development

Every organization is a complex, non-linear, and dynamic system. Gareth Morgan discussed eight different metaphors where they can be useful devices to create mental images to clarify and interpret our organizations. These eight metaphors are: machine, organism, brain, culture, political, flux and transformation, psychic prisons and instruments of domination. This combination of metaphors helps us understand our organization, analyze the structure, the leadership style (NAGY, December 2014). In this paper I will discuss the different metaphors of a pharmaceutical company (X). It is a growing pharmaceutical company, where reading and analyzing the different metaphors will definitely help them to prepare …

Mining Themes In Clinical Notes To Identify Phenotypes And To Predict Length Of Stay In Patients Admitted With Heart Failure, Ankita Agarwal, Tanvi Banerjee, William Romine, Krishnaprasad Thirunarayan, Lingwei Chen, Mia Cajita

Computer Science and Engineering Faculty Publications

Heart failure is a syndrome which occurs when the heart is not able to pump blood and oxygen to support other organs in the body. Identifying the underlying themes in the diagnostic codes and procedure reports of patients admitted for heart failure could reveal the clinical phenotypes associated with heart failure and to group patients based on their similar characteristics which could also help in predicting patient outcomes like length of stay. These clinical phenotypes usually have a probabilistic latent structure and hence, as there has been no previous work on identifying phenotypes in clinical notes of heart failure patients …

Hierarchical, Porous Hydrogels Demonstrating Structurally Dependent Mechanical Properties, Elisabeth Lloyd, Rami Alhasan, Sujata Dhakal, Svetlana Morozova, Douglas R. Tree, Robert Hickey

Faculty Publications

While hierarchical ordering is a distinctive feature of natural tissues and is directly responsible for their diverse and unique properties, research efforts to synthesize biomaterials have primarily focused on using molecular-based approaches without considering multiscale structure. Here, we report a bottom-up self-assembly process to produce highly porous hydrogels that resemble natural tissues both structurally and mechanically. Randomly oriented, physically crosslinked nanostructured micelles form the walls of aligned, polymer-rich pore walls that surround water-rich cavities. Extremely soft elastic modulus (<  1 kPa), highly stretchability (greater than 12-times), strain-hardening, and completely reversible deformation result from the hierarchical structure. Independent control of nano and macroscales is realized through the combination of polymer macromolecular parameters and processing conditions, directly impacting the resulting phase behavior. Here, we demonstrate precise control of the material structure and structure orientation over many orders of magnitude (e.g., nm – µm), and reveal how the multiscale structure directly impacts mechanical properties.

Decoding The Hydrodynamic Properties Of Microscale Helical Propellers From Brownian Fluctuations, Bernard Yurke

Materials Science and Engineering Faculty Publications and Presentations

The complex motility of bacteria, ranging from single-swimmer behaviors such as chemotaxis to collective dynamics, including biofilm formation and active matter phenomena, is driven by their microscale propellers. Despite extensive study of swimming flagellated bacteria, the hydrodynamic properties of their helical-shaped propellers have never been directly measured. The primary challenges to directly studying microscale propellers are 1) their small size and fast, correlated motion, 2) the necessity of controlling fluid flow at the microscale, and 3) isolating the influence of a single propeller from a propeller bundle. To solve the outstanding problem of characterizing the hydrodynamic properties of these propellers, …

Thermal Transport And Physical Characteristics Of Silver-Reinforced Biodegradable Nanolubricant, Jaime Taha-Tijerina, Karla Aviña, Nicolás Antonio Ulloa-Castillo, Dulce Viridiana Melo-Maximo

Informatics and Engineering Systems Faculty Publications

In this investigation, the thermal transport behavior of biodegradable lubricant reinforced with silver nanostructures (AgNs) at various filler fractions of 0.01, 0.05, 0.10, and 0.20 weight percent was evaluated over a temperature scan analysis, ranging from room temperature up to 60 °C. The experimental results revealed significant gradual enhancements in thermal conductivity as AgNs concentration and evaluating temperatures were increased. These improvements showed the important role of nanostructures’ interaction within the biodegradable lubricant. The thermal conductivity performance improved for nanolubricants ranging from 6.5% at 30 °C and 0.20 wt.% AgNs content up to a maximum 32.2%, which was obtained at …

Soybean Crop Coefficients Under Different Seeding Rates And Full And Limited Irrigation And Rainfed Management, Suat Irmak, Rupinder Sandhu

Department of Agricultural and Biological Systems Engineering: Faculty Publications

The effects of soybean seeding rates on evapotranspiration (ET_c) and grassand alfalfa-reference crop coefficients (K_co and K_cr) were investigated under five seeding rates (185,250, 247,000, 308,750, 370,500 and 432,250 seeds ha^-1) (62, 82, 103, 124 and 144% of the recommended seeding rate of 300,000 seeds ha^-1 in the experimental region) and different irrigation strategies (i.e. full irrigation treatment [FIT], limited irrigation of 75% FIT and 50% FIT and rainfed treatment). K_co and K_cr values were developed for each soybean growth stage. The seasonal ET_c ranged from 460 mm for …

Fe Nanoparticles Encapsulated In N-Doped Porous Carbon For Efficient Oxygen Reduction In Alkaline Media, Chun-Yan Li, Rui Zhang, Xiao-Jie Ba, Xiao-Le Jiang, Yao-Yue Yang

Journal of Electrochemistry

Rational design and synthesis of non-precious-metal catalyst plays an important role in improving the activity and stability for oxygen reduction reaction (ORR) but remains a major challenge. In this work, we used a facile approach to synthesize iron nanoparticles encapsulated in nitrogen-doped porous carbon materials (Fe@N-C) from functionalized metal-organic frameworks (MOFs, MET-6). Embedding Fe nanoparticles into the carbon skeleton increases the graphitization degree and the proportion of graphitic N as well as promotes the formation of mesopores in the catalyst. The Fe@N-C-30 catalyst showed the excellent ORR activity in alkaline solutions (E₀ = 0.97 V vs. RHE, E_{1/2 …}