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Cislunar Navigation Techniques And Navigation Performance Optimization, Quinn P. Moon

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Nova-C is a lunar lander developed by the private company Intuitive Machines to deliver commercial payloads to the Moon. The IM-1 mission set for 2023 will launch and land the Nova-C near the Moon's south pole. In this research, various navigation techniques are explored to determine the lander's position and velocity during key segments. This process is studied for key mission events including trajectory correction maneuvers (TCMs), lunar orbit insertion (LOI), and descent orbit insertion (DOI). Each mission segment, referred to as an Orbit Determination Segment (OD), is analyzed with three different navigation techniques: Monte Carlo Analysis, Linear Covariance Analysis, …

Methods To Study Activity Dependent Protein Synthesis In Autism Spectrum Disorder, Megan Webb, Karin F K Ejendal, Tamara L. Kinzer-Ursem

Discovery Undergraduate Interdisciplinary Research Internship

It is estimated by the World Health Organization that 1 in 100 children have autism spectrum disorder (ASD), a condition characterized by neurological differences that may impact a person’s learning or behavior. Clinically, ASD symptoms are alleviated with behavioral or pharmacological therapies, however, not all patients respond to these interventions. Deep brain stimulation (DBS) is a promising treatment of Parkinson’s disease that could also be effective in treating ASD. SynGAP1 is a protein involved in neuronal action that is crucial for regulating synaptic plasticity. Mutations in the SYNGAP1 gene causing haploinsufficiency can result in the manifestation of ASD symptoms. This …

Climate-Driven Changes In Water Quality By Physiographic Region: A Case Study Of Taos County, New Mexico, Michaela Eamma

Civil and Environmental Engineering Theses and Dissertations

Socioeconomic growth and stability in rural regions of the United States where agriculture is the dominant industry are highly reliant on access to sufficient surface water supplies. The water quantity crisis experienced worldwide in recent years has introduced questions about how to best maintain the quality of our remaining resources. Ensuring adequate access to drinking and irrigation water mandates that we protect existing surface water sources and anticipate future threats to quality. The impact of climate change on surface water quality is not spatially uniform, introducing the need to study the water-atmosphere-land system comprehensively.

This research aims to study the …

Missing Value Imputation For Single Omics And Multi-Omics Data, Meng Song

Dissertations

The integration analyses of multi-omics data have the advantages of extending our understanding of biological system across multiple omics layers, unraveling the functional mechanism of complex disease development, and refining the discovery of novel drug targets. However, multi-omics studies often face challenges such as data heterogeneity, missing values problem, interpretability, and imbalance classes. Among these challenges, the missing values problem is a critical issue for large cohort studies as not all samples will get a complete measurement for all the omics layers. To address the problem of missing values in multi-omics data, I focused on the imputation of completely missing …

Designing A Naabsa Class Tanker Ship With Bottom Protection From Ground, Victor A. Kulesh, Mathias B. Prasetio, Fam Chung Hiep

Journal of Mechanical Engineering Science and Technology (JMEST)

Indonesia is the world's largest archipelago country with a high potential for economic development and top producer and exporter of palm oil. As an archipelago country, the most efficient cargo transportation routes are through rivers and seas. Designing and building tankers, taking into account the specifics of the operation, are relevant. The paper considers the issues of designing a tanker for the transportation of crude palm oil with a defined operation area and route. The general concept of the vessel is proposed, taking into account the restrictions on the navigation area and draft for operation in the river. Particular attention …

Molybdenum Disulfide (Mos₂) As A Nanocellulose Substrate, Mariana Torres, Dylan Seiffert, Elise Hong-Miller, T. E. Kidd

Summer Undergraduate Research Program (SURP) Symposium

Cellulose is a substance abundant in nature, found in fruits and vegetables, plant cell walls (National Center for Biotechnology Information, 2023), and wood (Sjostrom, 1993). The abundance of cellulose is attributable to its linear chemical structure, as it is composed of long strands of glucose molecules linked together by hydrogen atoms, which enable the substance to withstand significant pressure without breaking (Rongpipi et al., 2019). This property—known as high tensile strength—is joined by its non-toxicity and sustainability, given cellulose may be degraded and renewed naturally (Kaur, 2021). These various properties indicate versatility, and its resultant current and desired uses—such as …

Flow Through Processing Of Nanocellulose For Space Exploration Applications, Dylan Seiffert, T. E. Kidd

Summer Undergraduate Research Program (SURP) Symposium

Nanocellulose is synthesized from cellulose, which is the most abundant organic molecule found in nature. Nanocellulose solids are biodegradable and have a strength-to-weight ratio eight times that of steel¹. The production of nanocellulose solids is challenging due to the large volume loss that occurs during the curing process as well as the time and cost associated with ultrasonic processing. The loss of volume during curing often results in cracking and deformation of the cured solid. The issues caused by the large volume loss can be mitigated using additives that do not compromise the strength, shape, or machineability of …

Impacts And Applications Of Vegetable Glycerin On Nanocellulose, Elise Hong-Miller, Dylan Seiffert, T. E. Kidd

Summer Undergraduate Research Program (SURP) Symposium

Nanocellulose is created by breaking down cellulose, the most common organic molecule found in nature. Nanocellulose has attractive properties, such as a very high strength-to-weight ratio, for many different applications. A major challenge is that nanocellulose has a very high shrinkage % (~90%) when it is dried, as well as a strong probability to crack. Different additives can be added in varying amounts to either mitigate or intensify these aspects, as well as affect its drying conditions. This investigation is helping the National Aeronautics and Space Administration (NASA) and the U.S. Army to find a use for this highly renewable …

Serum Metabolomic Profiling For Colorectal Cancer Using Machine Learning, Ria Nur Puspa Sari, Diah Balqis Ikfi Hidayati, Arleni Bustami

Indonesian Journal of Medical Chemistry and Bioinformatics

Background: Colorectal cancer is one of the deadliest diseases with a high prevalence worldwide and is characterized by the appearance of adenomatous polyps in the colon mucosa which are at high risk of developing into colorectal cancer. This study aims to use serum metabolites as promising non-invasive biomarkers for colorectal cancer detection and prognostication. Differences in serum metabolites in patients with adenomatous polyps, colorectal cancer, and healthy controls are considered to be able to support the prognosis of colorectal cancer. Methods: Metabolite dataset is taken from the Metabolomic Workbench. Analysis and validation are carried out in silico using machine learning …

Recent Progress Of Bifunctional Electrocatalysts For Oxygen Electrodes In Unitized Regenerative Fuel Cells, Tian-Long Zheng, Ming-Yu Ou, Song Xu, Xin-Biao Mao, Shi-Yi Wang, Qing-Gang He

Journal of Electrochemistry

Unitized regenerative fuel cells (URFCs), which oxidize hydrogen to water to generate electrical power under thefuel cells (FCs) mode and electrolyze water to hydrogen under the water electrolysis (WE) mode for recycling, areknown as clean and sustainable energy conversion devices. In contrast to the hydrogen oxidation reaction (HOR) andhydrogen evolution reaction (HER) on the hydrogen electrode side, the sluggish kinetics of oxygen reduction reaction(ORR) and oxygen evolution reaction (OER) on the oxygen electrode side requires highly efficient bifunctional oxygencatalysts. Conventional precious metal oxygen catalysts combine Pt and IrO₂ with excellent ORR and OER activities toachieve bifunctional electrocatalysis performance, but …

62nd Annual Rocky Mountain Conference On Magnetic Resonance

Rocky Mountain Conference on Magnetic Resonance

Final program, abstracts, and information about the 62nd annual meeting of the Rocky Mountain Conference on Magnetic Resonance, co-endorsed by the Colorado Section of the American Chemical Society and the Society for Applied Spectroscopy. Held in Sonesta Denver Downtown, Denver, Colorado, July 23-27, 2023.

Multifunctional Graphene–Polymer Nanocomposite Sensors Formed By One-Step In Situ Shear Exfoliation Of Graphite, Ali Ashraf, Elizabeth Chang, Md Ashiqur Rahman, Dipannita Ghosh, Nazmul Islam, Jennifer K. Lynch-Branzoi

Mechanical Engineering Faculty Publications

Graphene nanocomposites are a promising class of advanced materials for sensing applications; yet, their commercialization is hindered due to impurity incorporation during fabrication and high costs. The aim of this work is to prepare graphene–polysulfone (G−PSU) and graphene–polyvinylidene fluoride (G−PVDF) nanocomposites that perform as multifunctional sensors and are formed using a one-step, in situ exfoliation process whereby graphite is exfoliated into graphene nanoflakes (GNFs) directly within the polymer. This low-cost method creates a nanocomposite while avoiding impurity exposure since the raw materials used in the in situ shear exfoliation process are graphite and polymers. The morphology, structure, thermal properties, and …

Editorial: Intervertebral Disc Degeneration And Osteoarthritis: Mechanisms Of Disease And Functional Repair., Graciosa Q Teixeira, Jana Riegger, Raquel M Gonçalves, Makarand V. Risbud

Department of Orthopaedic Surgery Faculty Papers

No abstract provided.

Scalable Production Of Peptides For Enhanced Struvite Formation Via Expression On The Surface Of Genetically Engineered Microbes, Jacob D. Hostert, Quincy A. Spitzer, Paola Giammattei, Julie N. Renner

Faculty Scholarship

A promising method for recycling phosphate from wastewater is through precipitation of struvite (MgNH4PO4·6H2O), a slow-release fertilizer. Peptides have been shown to increase the yield of struvite formation, but producing peptides via solid phase synthesis is cost prohibitive. This work investigates the effects of peptide-expressing bacteria on struvite precipitation to provide a sustainable and cost-efficient means to enhance struvite precipitation. A peptide known for increased struvite yield was expressed on a membrane protein in Escherichia coli(E. coli), and then 5 mL precipitation reactions were performed in 50 mL culture tubes for at least 15 min. The yield of struvite crystals …

Liposomes For The Treatment Of Brain Cancer—A Review, Richu Raju, Waad H. Abuwatfa, William G. Pitt, Ghaleb A. Husseini

Faculty Publications

Due to their biocompatibility, non-toxicity, and surface-conjugation capabilities, liposomes are effective nanocarriers that can encapsulate chemotherapeutic drugs and facilitate targeted delivery across the blood–brain barrier (BBB). Additionally, strategies have been explored to synthesize liposomes that respond to internal and/or external stimuli to release their payload controllably. Although research into liposomes for brain cancer treatment is still in its infancy, these systems have great potential to fundamentally change the drug delivery landscape. This review paper attempts to consolidate relevant literature regarding the delivery to the brain using nanocarriers, particularly liposomes. The paper first briefly explains conventional treatment modalities for cancer, followed …

A Natural Organic Artificial Synaptic Device Made From A Honey And Carbon Nanotube Admixture For Neuromorphic Computing, Md Mehedi Hasan Tanim, Zoe Templin, Kaleb Hood, Jun Jiao, Feng Zhao

Electrical and Computer Engineering Faculty Research & Creative Works

Artificial synaptic devices are the essential hardware component in emerging neuromorphic computing systems by mimicking biological synapse and brain functions. When made from natural organic materials such as protein and carbohydrate, they have potential to improve sustainability and reduce electronic waste by enabling environmentally friendly disposal. In this paper, a new natural organic memristor based artificial synaptic device is reported with the memristive film processed by a honey and carbon nanotube (CNT) admixture, that is, honey-CNT memristor. Optical microscopy, scanning electron microscopy, and micro-Raman spectroscopy are employed to analyze the morphology and chemical structure of the honey-CNT film. The device …

A Review On Membrane Fouling Prediction Using Artificial Neural Networks (Anns), Waad H. Abuwatfa, Nour Al Sawaftah, Naif Darwish, William G. Pitt, Ghaleb A. Husseini

Faculty Publications

Membrane fouling is a major hurdle to effective pressure-driven membrane processes, such as microfiltration (MF), ultrafiltration (UF), nanofiltration (NF), and reverse osmosis (RO). Fouling refers to the accumulation of particles, organic and inorganic matter, and microbial cells on the membrane’s external and internal surface, which reduces the permeate flux and increases the needed transmembrane pressure. Various factors affect membrane fouling, including feed water quality, membrane characteristics, operating conditions, and cleaning protocols. Several models have been developed to predict membrane fouling in pressure-driven processes. These models can be divided into traditional empirical, mechanistic, and artificial intelligence (AI)-based models. Artificial neural networks …

Physiologically Relevant Fluid Shear Stress Induced Receptor Conversion In Hormone Receptor-Positive (Hr+) Breast Cancer, Jonathan James Cuccia

LSU Doctoral Dissertations

Breast cancer is the most common type of cancer among all people in the United States as of 2023 and often has devastating impacts on afflicted patients. Although some treatments show great efficacy against primary breast tumors, none have been able to significantly reduce the mortality rate of breast cancer once it has metastasized to distant sites. In primary, hormone receptor-positive (HR+) breast cancers, endocrine therapies are often used as first-line treatments and are generally well-tolerated. However, as the disease progresses, these previously sensitive cancers can become resistant to endocrine therapies and continue proliferating despite them. Therefore, there is a …

Plant Stem Undergraduate Symposium, David Britt

Biological Engineering Faculty Publications

No abstract provided.

Coastal Environments: Mine Discharges And Infringements On Indigenous Peoples’ Rights, Charles Kerfoot, Gary Swain, Luis M. Verissimo, Erin Johnston, Carol Maclennan, Daniel Schneider, Noel Urban

Michigan Tech Publications

Over a century ago, copper mills on the Keweenaw Peninsula of Lake Superior sluiced 64 million metric tonnes (MMT) of tailings into coastal waters, creating a metal-rich “halo”. Here we show that relatively small discharges can spread widely in time and space. Mass Mill (2.9 MMT) dumping into Lake Superior also illustrates the complexity of interactions with Indigenous Peoples. A combination of aerial photos, LiDAR, and a microscope technique for distinguishing end-member particles traces the migration of tailings. The clay fraction spread rapidly across Keweenaw Bay and curled into terminal L’Anse Bay, within tribal Reservation boundaries. The coarse stamp sand …

Estudio Termoquímico Asistido Por Computadora De Los Polifenoles Presentes En La Fresa [Thermochemical Computer Assisted Study Of Polyphenols Presented In Strawberry], Federico Lopez, Jeimmy Rocio Bonilla Méndez, Luis Ricárdez Sandoval, Hiram Moya, Daniela Mainardi, Arturo González Quiroga, Jeffrey Leon-Pulido

Manufacturing & Industrial Engineering Faculty Publications

Las fresas son un alimento importante en Latinoamérica debido a sus componentes químicos, puesto que son una considerable fuente de calorías y polifenoles. Estos elementos son útiles por su capacidad antioxidante y otras propiedades beneficiosas para la salud. Sin embargo, la presión y la temperatura pueden llegar a afectar la integridad molecular de estos componentes, por lo tanto, en el proceso de producción de diferentes productos basados en fresas, se requiere estudiar las propiedades termoquímicas de los diferentes polifenoles presentes en esta fruta. Para ello, se extrajeron datos de las principales familias de polifenoles, antocianinas, flavanoles, flavonoles, ácidos hidroxibenzoicos y …

From Waste To Energy: The Electrochemical Reduction Of Co2 Using Recycled Nanostructured Catalysts, Ibrahim Badawy

Theses and Dissertations

The reduction of carbon dioxide (CO₂RR) using electrochemistry is a promising solution for the burgeoning global energy crisis. The overall vision of its implementation relies on renewable energy sources to power the reaction creating carbon neutral products and effectively closing the carbon cycle. Research in this field has come a long way since its inception in the mid-1900s. However, there remain significant hurdles and important considerations to overcome in order to reach full commercialization. Most electrocatalysts tested for CO₂RR have been designed solely for maximum performance while ignoring the environmental consequences if such a material were …

Who Is (Communicatively More) Responsible Behind The Wheel? Applying The Theory Of Communicative Responsibility To Tam In The Context Of Using Navigation Technology, Sungbin Youk, Hee Sun Park

Human-Machine Communication

By examining how perceived usefulness and ease of use relate to the user’s perception (i.e., communicative responsibility), the communicative behavior of the navigation system (i.e., the landmarks used to give directions), and the context of driving (i.e., familiarity of the driving location), this study applies the theory of communicative responsibility to the technology acceptance model to better understand why users are more likely to adopt certain navigation technologies while driving. We hypothesized that users’ perceived symmetry in communicative responsibility independently and interactively (with communicative behavior of the navigation system and the driving situation) affects perceived ease of use and usefulness …

Sovia: Sonification Of Visual Interactive Art, Lauryn Gayhardt

Computer Science and Engineering Master's Theses

Therapeutic Computational Creativity is an emerging domain that challenges us to explore applications of Computational Creativity systems to mental health and wellness. This work presents SOVIA, an interactive system that endows Claude Monet’s art with responsive auditory experiences. SOVIA uses computer vision trained on Monet’s artwork to take the user “into the painting.'' When the user interacts with a digital version of Monet's landscapes, their mouse positions are mapped to sounds that artistically represent the objects that the user is currently exploring in the art. These interactive musical journeys have the potential to make classical art more captivating for modern …

Research Progress On Properties Of Fiber Modified Asphalt Mixture, Liang Bo, Zhang Haitao, Liu Zheng, Liao Wei

Journal of China & Foreign Highway

As a kind of asphalt mixture additive and stabilizer, fiber can effectively improve the performance index of asphalt pavement and extend the service life of asphalt pavement. Based on the analysis of relevant literature in China and abroad, this paper summarized the action mechanism of fiber modified asphalt and asphalt mixture, the effect of fiber content on properties, and the characteristics of different types of fiber modified asphalt. Fiber can effectively improve the high temperature property, low temperature property, and fatigue property of asphalt mixture, especially the resistance to low temperature and fatigue cracking of asphalt mixture. The modification effect …

Effect Of Temperature And Light On Characteristics Of Asphalt Emissions, Zhu Xuwei, Tian Bo

Journal of China & Foreign Highway

In order to study the effects of temperature and light on the characteristics of asphalt emissions, atmospheric pressure chemical ionization–time-of-flight mass spectrometer (APCI‑TOF MS) and electron impact ionization mass spectrometry (EI‑MS) were used to quantitatively characterize the composition information of PG 62-22 asphalt emissions at different temperatures (40–200 °C). The effects of different temperatures and light on total emission factor, SOA conversion factor, intermediate volatile organic compound (IVOC)/semi-volatile organic compound (SVOC) volume fraction, and aromatics volume fraction of asphalt emissions were studied. The results show that the components of asphalt emissions change with temperature, and the components are complex and …

Wave Attenuation Through Mangrove Forest Using Lidar Representation, Elizabeth Bogan

LSU Master's Theses

Mangrove forests can be found along the world’s intertidal tropical and sub-tropical coastlines. These forested wetlands provide many ecosystem services, including supporting coastal food chains, trapping sediment, and shoreline stabilization. Mangroves are also known for flood damage mitigation by dissipating waves and surge during flooding events. Thus, coastal communities declare a vested interest in the performance of the forest to mitigate flood damage. Physical models using artificial mangrove structures have shown that red mangrove-dominated fringe forests can protect built infrastructure by reducing wave height due to increased drag. One way to estimate the contribution of red mangrove (Rhizophora mangle) prop …

Multiple Ways To Implement And Infer Sentience, Nicolas Rouleau, Michael Levin

Animal Sentience

Segundo-Ortin & Calvo’s (S&C’s) thorough review of “plant neurobiology” presents evidence supporting the possibility of plant sentience. They make a compelling case that plants anticipate, assess risk, cooperate, mimic, and pursue goals, as do their animal counterparts. S&C point out that there is a double standard: behavioural patterns associated with subjective experiences in humans are considered valid for inferring cognition in non-human animals but not in diverse other systems including plants. We argue that cognitive functions, including sentience, can potentially be achieved by very different systems and their disparate substrates. We offer some context from the basal cognition literature and …

Ecg Recordings As Predictors Of Very Early Autism Likelihood: A Machine Learning Approach, Deepa Tilwani, Jessica Bradshaw, Amit Sheth, Christian O'Reilly

Publications

In recent years, there has been a rise in the prevalence of autism spectrum disorder (ASD). The diagnosis of ASD requires behavioral observation and standardized testing completed by highly trained experts. Early intervention for ASD can begin as early as 1–2 years of age, but ASD diagnoses are not typically made until ages 2–5 years, thus delaying the start of intervention. There is an urgent need for non-invasive biomarkers to detect ASD in infancy. While previous research using physiological recordings has focused on brain-based biomarkers of ASD, this study investigated the potential of electrocardiogram (ECG) recordings as an ASD biomarker …

Local Chlorhexidine Delivery For Periodontal Infection Therapy: A Short Review, Muhammad Guruh Najmudin, Azizah Intan Pangesty, Rini Riastuti, Sunarso Sunarso, Abdul Halim Abdullah

Journal of Materials Exploration and Findings

Oral diseases affected more than half of the world’s population. Periodontitis is the second biggest threat to oral health after dental caries. Periodontitis is an inflammation inside periodontal pockets caused by pathogenic microbial colonies which lead to destruction of bone tissue and soft tissue. Chlorhexidine gluconate is an antimicrobial agent that effective to destroy pathogenic microbial and cure periodontitis. Chlorhexidine gluconate is given locally using a carrier material to the infected area. There are several materials that can be used to deliver Chlorhexidine gluconate to the infected periodontal tissue such as gel, liquid (mouthwash), and chip. This short review aims …