Digital Commons Network^™

Direct Electrochemistry Of Chloroperoxidase At Gc Electrode Modified With Swnts, Hong-Xia Zhang, Xia-Qin Wu, Wen-Jing Hou, Wen Xie, Zhong-Qing Lu, Rong Wang, He-Xing Li

Journal of Electrochemistry

The chloroperoxidase(CPO) was immobilized onto the surface of SWNTs modified electrodes.The electrochemical behaviors of modified electrode have been investigated by cyclic voltammetry.The appearance of a pair of well-defined redox peaks in the CV curve indicated that SWNTs can promote the electron transfer reaction of CPO.The results of cyclic voltammetry in PBS of different pH,from 3~9,showed that the reaction of CPO on the modified electrode was with equal numbers of electron and protein.This readily prepared SWNTs modified electrode showed excellent stability and good catalysis to O₂.

Design And Testing Of A Pumpless Microelectromechanical System Nanoinjector, Quentin Theodore Aten

Theses and Dissertations

A deeper understanding of human development and disease is made possible partly through the study of genetically modified model organisms, such as the common mouse (Mus musculus). By genetically modifying such model organisms, scientists can activate, deactivate, or highlight particular characteristics. A genetically modified animal is generated by adding exogenous (foreign) genetic material to one or more embryonic cells at their earliest stages of development. Frequently, this exogenous genetic material consists of specially engineered DNA, which is introduced into a fertilized egg cell (zygote). When successfully introduced into the zygote, the exogenous DNA will be incorporated into the …

Synthesis And Characterization Of Novel Temperature-Responsive Dendritic Peg-Pdlla Star Polymers For Drug Delivery, Arunvel Kailasan

Theses and Dissertations

This study describes a novel thermoresponsive dendritic polyethylene glycol-poly(D, L-lactide) (PEG-PDLLA) core-shell nanoparticle with potential for drug delivery and controlled release. A series of dendritic PEG-PDLLA nanoparticles were synthesized through conjugation of PEG to Starburst™ polyamidoamine (PAMAM) dendrimer G3.0 and subsequent ring-opening polymerization of DLLA, in which PEG chain length (i.e., MW=1500, 6000 or 12000 Dalton) was varied; however, the feeding molar ratio of DLLA monomers to the overall PEG repeat units on the dendrimer surface was kept at 1:1. Linear PEG-PDLLA copolymers were also syntheiszed under the same condition and used as control. According to our results, dendritic PEG-PDLLA …

Accelerometer Based Measurement Of Body Movement For Communication, Play, And Creative Expression, Mark Nolan, Edward Burke, Frank Duignan

Conference Papers

This paper presents a newly designed wireless accelerometer-based movement measurement device. The device is capable of measuring activity ranging from gross body movements to more subtle vibrations emanating from the body, including laryngeal vibration and the mechanomyogram (mechanical vibrations from working muscles). The main body of the device, which is less than 20cm3 in volume and weighs less than 50g, contains a microcontroller, wireless transceiver, battery, and one accelerometer. A supplementary accelerometer module is connected to the main device by thin wires. This module is very light weight and can therefore be directly attached to the skin to measure laryngeal …

Corrosion Damage Studies Through Microscopy And Stress Analysis, Ronak Patel

Theses and Dissertations

Corrosion is the destructive result of chemical reaction between a metal or metal alloy and its environment. Airplanes, power generating plants, chemical process and manufacturing plants, concrete structure, and many others which widely uses aluminum alloy and stainless steel alloys are subjected to corrosion. The estimated cost of corrosion damage is in order of 3 to 5 percent of gross national product (GNP). Out of all forms of corrosion, pitting corrosion is most commonly observed in aluminum alloy 2024 and stainless steel type 316. There is a need to study the stress environment around the pits in order to predict …

Hardware Architectures And Implementations For Associative Memories : The Building Blocks Of Hierarchically Distributed Memories, Changjian Gao

Dissertations and Theses

During the past several decades, the semiconductor industry has grown into a global industry with revenues around $300 billion. Intel no longer relies on only transistor scaling for higher CPU performance, but instead, focuses more on multiple cores on a single die. It has been projected that in 2016 most CMOS circuits will be manufactured with 22 nm process. The CMOS circuits will have a large number of defects. Especially when the transistor goes below sub-micron, the original deterministic circuits will start having probabilistic characteristics. Hence, it would be challenging to map traditional computational models onto probabilistic circuits, suggesting a …

Transcriptome Analysis Identifies Novel Responses And Potential Regulatory Genes Involved In Seasonal Dormancy Transitions Of Leafy Spurge (Euphorbia Esula L.), David P. Horvath, Wun S. Chao, Jeffrey C. Suttle, Jyothi Thimmapuram, James V. Anderson

Cyber Center Publications

Dormancy of buds is a critical developmental process that allows perennial plants to survive extreme seasonal variations in climate. Dormancy transitions in underground crown buds of the model herbaceous perennial weed leafy spurge were investigated using a 23 K element cDNA microarray. These data represent the first large-scale transcriptome analysis of dormancy in underground buds of an herbaceous perennial species. Crown buds collected monthly from August through December, over a five year period, were used to monitor the changes in the transcriptome during dormancy transitions.

Hydrophobic Silver Nanoparticles Trapped In Lipid Bilayers: Size Distribution, Bilayer Phase Behavior, And Optical Properties, Geoffrey D. Bothun

Chemical, Biomolecular, and Materials Engineering Faculty Publications

Background: Lipid-based dispersion of nanoparticles provides a biologically inspired route to designing therapeutic agents and a means of reducing nanoparticle toxicity. Little is currently known on how the presence of nanoparticles influences lipid vesicle stability and bilayer phase behavior. In this work, the formation of aqueous lipid/nanoparticle assemblies (LNAs) consisting of hydrophobic silver-decanethiol particles (5.7 ± 1.8 nm) embedded within 1,2-dipalmitoyl-sn-glycero-3- phosphocholine (DPPC) bilayers is demonstrated as a function of the DPPC/Ag nanoparticle (AgNP) ratio. The effect of nanoparticle loading on the size distribution, bilayer phase behavior, and bilayer fluidity is determined. Concomitantly, the effect of bilayer incorporation on …

N,N’-Bis(3,5-Di-T-Butylsalicylideneimine) Propanediamine And Its Some Tetradentate Schiff Base Complexes Synthesis, Characterization And Thermal Study, Fatih Dogan, M. Ulusoy, O. F. Ozturk, I. Kaya, B. Salih

Materials Science and Engineering Faculty Research & Creative Works

Several mononuclear Co (II), Ni (II), Cu (II) and Fe (II) complexes of tetradentate salpren-type diamine, obtained from 3,5-di-tert–butyl-2-hydroxybenzaldehyde and 1,3-diaminopropane have been prepared and characterized by analytical, spectroscopic (FTIR, UV-Vis) techniques, magnetic susceptibility measurements and thermogravimetric analyses (TG). The thermodynamic and thermal properties of complexes have been investigated. For further characterization direct insertion probe-mass spectrometry (DIP-MS) was used and the fragmentation pattern and also stability of the ions were evaluated. The characterization of the end products of the decomposition was achieved by X-ray diffraction. The thermal stabilities of metal complexes of N,N’-bis(3,5-di-t-butylsalicylideneimine) propane diamine ligand (L) were found as …

Angiogenic Potential Of Human Macrophages On Electrospun Bioresorbable Vascular Grafts, Koyal Garg

Theses and Dissertations

The aim of this study was to investigate macrophage interactions with electrospun scaffolds and quantify the expression of vital angiogenic growth factors in vitro. This study will further help in evaluating the potential of these electrospun constructs as vascular grafts for tissue repair and regeneration in situ. Human peripheral blood macrophages were seeded in serum free media on electrospun (10 mm) discs of polydioxanone (PDO), elastin and PDO:elastin blends (50:50, 70:30 and 90:10). The growth factor secretion was analyzed by ELISA. Macrophages produced high levels of vascular endothelial growth factor (VEGF) and acidic fibroblast growth factor (aFGF). Transforming growth factor …

Multi-Break Rearrangements And Breakpoint Re-Uses: From Circular To Linear Genomes, Max A. Alekseyev

Faculty Publications

Multi-break rearrangements break a genome into multiple fragments and further glue them together in a new order. While 2-break rearrangements represent standard reversals, fusions, fissions, and translocations, 3-break rearrangements represent a natural generalization of transpositions. Alekseyev and Pevzner (2007a, 2008a) studied multi-break rearrangements in circular genomes and further applied them to the analysis of chromosomal evolution in mammalian genomes. In this paper, we extend these results to the more difficult case of linear genomes. In particular, we give lower bounds for the rearrangement distance between linear genomes and for the breakpoint re-use rate as functions of the number and proportion …

Improving Reversal Median Computation Using Commuting Reversals And Cycle Information, William Arndt, Jijun Tang

Faculty Publications

In the past decade, genome rearrangements have attracted increasing attention from both biologists and computer scientists as a new type of data for phylogenetic analysis. Methods for reconstructing phylogeny from genome rearrangements include distance-based methods, MCMC methods, and direct optimization methods. The latter, pioneered by Sankoff and extended with the software suites GRAPPA and MGR, is the most accurate approach, but is very limited due to the difficulty of its scoring procedure—it must solve multiple instances of the reversal median problem to compute the score of a given tree. The reversal median problem is known to be NP-hard and all …

The Peer-Reviewing Game, Marius C. Silaghi, Makoto Yokoo

Electrical Engineering and Computer Science Faculty Publications

We model a family of peer-reviewing processes as game-theoretic problems. The model helps to understand elements of existing peer-reviewing procedures, and to predict the impact of new mechanisms. The peer-reviewing for evaluation of scientific results submitted to conferences involves complex decision processes of independent participants. Significant tax-payer money is spent by governments for the advancement of science, and such governmental decisions are often based on outcomes of peer-reviewing in scientific conferences. Here we propose to analyze and design improved mechanisms for conference peer-reviewing, based on game-theoretic approaches. Real world conference peer-reviewing processes are overly complex and here we define and …

Ceas E-News 11.04.2008, College Of Engineering And Applied Sciences

College of Engineering and Applied Sciences News

CEAS student presents cell culture research at MSGC Conference

A Systematic Approach Towards Developing A Philosophy Of Engineering: Engineers Dancing With Philosophers, Mike Murphy

Presentations

No abstract provided.

Progress Toward Meeting The Challenges Of Our Coastal Urban Future, Juile Pullen, Jason Ching, David J. Sailor, William Thompson, Bob Bornstein, Darko Koracin

Mechanical and Materials Engineering Faculty Publications and Presentations

The article provides information on the Seventh Conference on Coastal Atmospheric and Oceanic Prediction and Processes, and the Seventh Symposium on the Urban Environment in San Diego, California on September 9-13, 2008. Topics include the heterogeneity of urban areas, coastal vulnerabilities, urban planning, and emergency response modeling. The conference featured several speakers including Walter Dabberdt and James Voogt.

Image Analyses Of Two Crustacean Exoskeletons And Implications Of The Exoskeletal Microstructure On The Mechanical Behavior, Liang Cheng, Liyun Wang, Anette M. Karlsson

Mechanical Engineering Faculty Publications

The microstructures of exoskeletons from Homarus americanus (American lobster) and Callinectes sapidus (Atlantic blue crab) were investigated to elucidate the mechanical behavior of such biological composites. Image analyses of the cross-sectioned exoskeletons showed that the two species each have three well-defined regions across the cuticle thickness where the two innermost regions (exocuticle and endocuticle) are load bearing. These regions consist of mineralized chitin fibers aligned in layers, where a gradual rotation of the fiber orientation of the layers results in repeating stacks. The exocuticle and endocuticle of the two species have similar morphology, but different thicknesses, number of layers, and …

Andrews University Engineering Program Achieves Abet Accreditation, Keri Suarez

Lake Union Herald

No abstract provided.

Extracellular Matrix Protein Orientation By Adsorption On Self-Assembled Monolayers Controls Nonviral Gene Delivery, Beth A. Duensing, Angela K. Pannier

Department of Agricultural and Biological Systems Engineering: Presentations and White Papers

To date, most efforts to understand and improve the efficiency of nonviral gene delivery have focused on altering the physicochemical properties of delivery systems and developing new delivery strategies. The importance of the cellular microenvironment in achieving successful nonviral gene transfer has not been thoroughly examined, though proteins of the extracellular matrix (ECM) mediate cell adhesion and serve to regulate cellular behavior that may, in turn, dictate the cellular responsiveness to nonviral gene delivery. Self-assembled monolayers (SAMs) of alkanethiols on gold were used to control adsorption of ECM molecules and thus control the architecture of the extracellular environment presented to …

Design And Optimization Of A Blood Vessel Mimic Bioreactor System For The Evaluation Of Intravascular Devices In Simple And Complex Vessel Geometries, Sara M. Leifer

Master's Theses

Coronary artery disease affects millions of people and the ability to detect and treat the disease is advancing at a rapid rate. As a result, the development of intravascular technologies is the focus of many medical device manufacturers. Specifically, coronary stent implantation is being performed in an increasing number of patients and a number of new stent designs have been introduced to the market, resulting in the need for improved preclinical testing methods. An in vitro tissue engineered “blood vessel mimic” (BVM) system has previously been established and its feasibility for the initial testing of newly emerging intravascular technology has …

2008 Scholars And Artists Bibliography, Rajshehkar G. Javalgi Dr., Michael Schwartz Library, Cleveland State University, Friends Of The Michael Schwartz Library

Scholars and Artists Bibliographies

This bibliography was created for the annual Friends of the Michael Schwartz Library Scholars and Artists Reception, recognizing scholarly and creative achievements of Cleveland State University faculty, staff and emeriti. Dr. Rajshekhar Javalgi was the guest speaker.

Cmol/Cmos Hardware Architectures And Performance/Price For Bayesian Memory - The Building Block Of Intelligent Systems, Mazad Shaheriar Zaveri

Dissertations and Theses

The semiconductor/computer industry has been following Moore's law for several decades and has reaped the benefits in speed and density of the resultant scaling. Transistor density has reached almost one billion per chip, and transistor delays are in picoseconds. However, scaling has slowed down, and the semiconductor industry is now facing several challenges. Hybrid CMOS/nano technologies, such as CMOL, are considered as an interim solution to some of the challenges. Another potential architectural solution includes specialized architectures for applications/models in the intelligent computing domain, one aspect of which includes abstract computational models inspired from the neuro/cognitive sciences.

Consequently in this …

Methodology For Developing A Functional Multiscale Architecture Model System Towards Future Integrated Circuits, Yamini Yadov

Dissertations and Theses

Detection of the biochemical species in the environmental pollution, industrial emission monitoring, medical diagnosis, public security, agriculture and a variety of industries has resulted in the emerging need for a generation of high density nanostructured sensor arrays. The fundamental two terminal and three terminal device components because of their potential for specificity eventually have to be integrated into miniaturized and portable nanoarray sensors. One of the key components in these nanosensors is the development of building functional building blocks that improve device performance capabilities. This research is focused on methodology for developing fundamental, functional, multiscale architecture model system for generating …

Development And Annotation Of Perennial Triticeae Ests And Ssr Markers., B.S. Bushman, S R Larson, I W Mott, P F Cliften, R R Wang, N J Chatterton, A G Hernandez, S Ali, R W Kim, Jyothi Thimmapuram, G Gong, L Liu, M A Mikel

Cyber Center Publications

Triticeae contains hundreds of species of both annual and perennial types. Although substantial genomic tools are available for annual Triticeae cereals such as wheat and barley, the perennial Triticeae lack sufficient genomic resources for genetic mapping or diversity research. To increase the amount of sequence information available in the perennial Triticeae, three expressed sequence tag (EST) libraries were developed and annotated for Pseudoroegneria spicata, a mixture of both Elymus wawawaiensis and E. lanceolatus, and a Leymus cinereus x L. triticoides interspecific hybrid. The ESTs were combined into unigene sets of 8 780 unigenes for P. spicata, 11 281 unigenes for …

Newsletters For The Larsen Tractor Museum, Tractor Museum

Lester F. Larsen Tractor Museum: Planning and Development Documents

No abstract provided.

Imaging Of Buried Utilities By Ultra Wideband Sensory Systems, Arun Prakash Jaganathan

Doctoral Dissertations

Third-party damage to the buried infrastructure like natural gas pipelines, water distribution pipelines and fiber optic cables are estimated at $10 billion annually across the US. Also, the needed investment in upgrading our water and wastewater infrastructure over the next 20 years is estimated by Environmental Protection Agency (EPA) at $400 billion, however, non-destructive condition assessment technologies capable of providing quantifiable data regarding the structural integrity of our buried assets in a cost-effective manner are lacking. Both of these areas were recently identified several U.S. federal agencies as 'critical national need'. In this research ultra wideband (UWB) time-domain radar technology …

Engineering@Nebraska - Fall 2008

Engineering@Nebraska (Alumni Magazine)

Table of Contents:

Front & Center
A Welcome Home: Zero Net Energy Test House unites university and industry as students' learning is caught green-handed
Making their mark on mars: Huskers at Honeybee, a New York City robotics firm, work on Mars missions
Epigenetics: A dialogue between biologists and engineers: Joe Turner, professor and chair of the Department of Engineering Mechanics, collaborates with UNL plant scientist Sally McKenzie on nanoscale work with huge potential
Energy monitoring on the home front: Together with OPPD, Nebraska Engineering studies devices to promote efficiency
Wave of the future: Biological Systems Engineering professor Greg Bashford creates …

Stochastic Event Reconstruction Of Atmospheric Contaminant Dispersion Using Bayesian Inference, Inanc Senocak, Nicolas W. Hengartner, Margaret B. Short, W. Brent Daniel

Mechanical and Biomedical Engineering Faculty Publications and Presentations

Environmental sensors have been deployed in various cities for early detection of contaminant releases into the atmosphere. Event reconstruction and improved dispersion modeling capabilities are needed to estimate the extent of contamination, which is required to implement effective strategies in emergency management. To this end, a stochastic event reconstruction capability that can process information from an environmental sensor network is developed. A probability model is proposed to take into account both zero and non-zero concentration measurements that can be available from a sensor network because of a sensor’s specified limit of detection. The inference is based on the Bayesian paradigm …

Hardware Implementation Of An Ais-Based Optimal Excitation Controller For An Electric Ship, Chuan Yan, Ganesh K. Venayagamoorthy, Keith Corzine

Electrical and Computer Engineering Faculty Research & Creative Works

The operation of high energy loads on Navy's future electric ships, such as directed energy weapons, will cause disturbances in the main bus voltage and impact the operation of the rest of the power system when the pulsed loads are directly powered from the main dc bus. This paper describes an online design and laboratory hardware implementation of an optimal excitation controller using an artificial immune system (AIS) based algorithm. The AIS algorithm, a clonal selection algorithm (CSA), is used to minimize the effects of pulsed loads by improved excitation control and thus, reduce the requirement on energy storage device …

Decision Theory On Dynamic Domains Nabla Derivatives And The Hamilton-Jacobi-Bellman Equation, John E. Seiffertt Iv, Donald C. Wunsch, Suman Sanyal

Electrical and Computer Engineering Faculty Research & Creative Works

The time scales calculus, which includes the study of the nabla derivatives, is an emerging key topic due to many multidisciplinary applications. We extend this calculus to Approximate Dynamic Programming. In particular, we investigate application of the nabla derivative, one of the fundamental dynamic derivatives of time scales. We present a nabla-derivative based derivation and proof of the Hamilton-Jacobi-Bellman equation, the solution of which is the fundamental problem in the field of dynamic programming. By drawing together the calculus of time scales and the applied area of stochastic control via Approximate Dynamic Programming, we connect two major fields of research.